Cancer somatic mutations disrupt functions of the EphA3 receptor tyrosine kinase through multiple mechanisms

Biochemistry

Volumn 51, Issue 7, 2012, Pages 1464-1475

  Lisabeth, Erika M ^a   Fernandez, Carlos ^a   Pasquale, Elena B ^a,b  

^a BURNHAM INSTITUTE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CANCER PATIENTS; CANCER PROGRESSION; CELL SHAPES; CELLULAR PROCESS; EPHRIN LIGANDS; GENETIC SCREENS; GLIOBLASTOMAS; HEPATOCELLULAR; KINASE ACTIVITY; RECEPTOR CELLS; RECEPTOR TYROSINE KINASE; SOMATIC MUTATION;

AMINO ACIDS; CELL ADHESION; CELL MEMBRANES; ENZYMES; SIGNAL TRANSDUCTION; TUMORS;

DISEASES;

EPHRIN; EPHRIN RECEPTOR A3; PROTEIN TYROSINE KINASE;

ARTICLE; COLORECTAL CANCER; ENZYME PHOSPHORYLATION; GENETIC SCREENING; GLIOBLASTOMA; HUMAN; HUMAN CELL; LIVER CELL CARCINOMA; LUNG CANCER; MELANOMA; NEOPLASM; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; SOMATIC MUTATION;

CELL MEMBRANE; DISEASE PROGRESSION; EPHRIN-A3; FIBRONECTINS; GENE EXPRESSION REGULATION, NEOPLASTIC; HEK293 CELLS; HUMANS; IMMUNOBLOTTING; MODELS, BIOLOGICAL; MODELS, GENETIC; MUTATION; NEOPLASMS; PROTEIN CONFORMATION; PROTEIN KINASES; PROTEIN STRUCTURE, TERTIARY; RECEPTOR PROTEIN-TYROSINE KINASES; SIGNAL TRANSDUCTION;

EID: 84857384965     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi2014079     Document Type: Article

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