Dual targeting of EphA2 and ER restores Tamoxifen sensitivity in ER/EphA2-positive breast cancer

Breast Cancer Research and Treatment

Volumn 127, Issue 2, 2011, Pages 375-384

  Gökmen Polar, Yesim ^a   Toroni, Rachel A ^a   Hocevar, Barbara A ^a,b   Badve, Sunil ^a,b   Zhao, Qianqian ^a   Shen, Changyu ^a   Bruckheimer, Elizabeth ^c   Kinch, Michael S ^c   Miller, Kathy D ^a,b  

^a INDIANA UNIVERSITY   (United States)

^b INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c MEDIMMUNE   (United States)

Author keywords

Breast cancer; EphA2; Estrogen receptor; Tamoxifen sensitivity

Indexed keywords

EPHRIN RECEPTOR A2; ESTROGEN RECEPTOR; FOCAL ADHESION KINASE 1; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY EA5; TAMOXIFEN; TYROSINE; UNCLASSIFIED DRUG; WNT PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CANCER INHIBITION; CELL STRAIN MCF 7; CONTROLLED STUDY; DRUG SENSITIVITY; GENE OVEREXPRESSION; GENETIC TRANSFECTION; GROWTH INHIBITION; HORMONAL REGULATION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTINEOPLASTIC AGENTS, HORMONAL; BETA CATENIN; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; DISEASE MODELS, ANIMAL; DRUG RESISTANCE, NEOPLASM; ESTROGENS; FEMALE; FOCAL ADHESION KINASE 1; GENE EXPRESSION; GENE EXPRESSION PROFILING; HUMANS; MICE; MICE, NUDE; PHOSPHORYLATION; RECEPTOR, EPHA2; RECEPTORS, ESTROGEN; SIGNAL TRANSDUCTION; TAMOXIFEN; TCF TRANSCRIPTION FACTORS; WNT PROTEINS;

EID: 79958240217     PISSN: 01676806     EISSN: 15737217     Source Type: Journal    
DOI: 10.1007/s10549-010-1004-y     Document Type: Article

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