메뉴 건너뛰기




Volumn 55, Issue 5, 2012, Pages 2427-2436

Novel targeted system to deliver chemotherapeutic drugs to EphA2-expressing cancer cells

Author keywords

[No Author keywords available]

Indexed keywords

EPHRIN RECEPTOR A2; PACLITAXEL;

EID: 84863291820     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm201743s     Document Type: Article
Times cited : (82)

References (51)
  • 3
    • 27144550160 scopus 로고    scopus 로고
    • Arming antibodies: Prospects and challenges for immunoconjugates
    • Wu, A. M.; Senter, P. D. Arming antibodies: prospects and challenges for immunoconjugates Nat. Biotechnol. 2005, 23 (9) 1137-1146
    • (2005) Nat. Biotechnol. , vol.23 , Issue.9 , pp. 1137-1146
    • Wu, A.M.1    Senter, P.D.2
  • 4
    • 22844436226 scopus 로고    scopus 로고
    • Recent advances in tumor-targeting anticancer drug conjugates
    • Jaracz, S.; Chen, J.; Kuznetsova, L. V.; Ojima, I. Recent advances in tumor-targeting anticancer drug conjugates Bioorg. Med. Chem. 2005, 13 (17) 5043-5054
    • (2005) Bioorg. Med. Chem. , vol.13 , Issue.17 , pp. 5043-5054
    • Jaracz, S.1    Chen, J.2    Kuznetsova, L.V.3    Ojima, I.4
  • 5
    • 0025047522 scopus 로고
    • New methods of drug delivery
    • Langer, R. New methods of drug delivery Science 1990, 249 (4976) 1527-1533
    • (1990) Science , vol.249 , Issue.4976 , pp. 1527-1533
    • Langer, R.1
  • 7
    • 33644781456 scopus 로고    scopus 로고
    • Multi-functional polymeric nanoparticles for tumour-targeted drug delivery
    • van Vlerken, L. E.; Amiji, M. M. Multi-functional polymeric nanoparticles for tumour-targeted drug delivery Expert Opin. Drug Delivery 2006, 3 (2) 205-216
    • (2006) Expert Opin. Drug Delivery , vol.3 , Issue.2 , pp. 205-216
    • Van Vlerken, L.E.1    Amiji, M.M.2
  • 8
    • 37749004225 scopus 로고    scopus 로고
    • Protein therapeutics: A summary and pharmacological classification
    • Leader, B.; Baca, Q. J.; Golan, D. E. Protein therapeutics: a summary and pharmacological classification Nat. Rev. Drug Discovery 2008, 7 (1) 21-39
    • (2008) Nat. Rev. Drug Discovery , vol.7 , Issue.1 , pp. 21-39
    • Leader, B.1    Baca, Q.J.2    Golan, D.E.3
  • 9
    • 0020053808 scopus 로고
    • Monoclonal antibodies in cancer
    • Marx, J. L. Monoclonal antibodies in cancer Science 1982, 216 (4543) 283-285
    • (1982) Science , vol.216 , Issue.4543 , pp. 283-285
    • Marx, J.L.1
  • 11
    • 0037033004 scopus 로고    scopus 로고
    • An ephrin mimetic peptide that selectively targets the EphA2 receptor
    • Koolpe, M.; Dail, M.; Pasquale, E. B. An ephrin mimetic peptide that selectively targets the EphA2 receptor J. Biol. Chem. 2002, 277 (49) 46974-46979
    • (2002) J. Biol. Chem. , vol.277 , Issue.49 , pp. 46974-46979
    • Koolpe, M.1    Dail, M.2    Pasquale, E.B.3
  • 13
    • 79961022478 scopus 로고    scopus 로고
    • Discovery of a linear peptide for improving tumor targeting of gene products and treatment of distal tumors by IL-12 gene therapy
    • Cutrera, J.; Dibra, D.; Xia, X.; Hasan, A.; Reed, S.; Li, S. Discovery of a linear peptide for improving tumor targeting of gene products and treatment of distal tumors by IL-12 gene therapy Mol. Ther. 2011, 19 (8) 1468-1477
    • (2011) Mol. Ther. , vol.19 , Issue.8 , pp. 1468-1477
    • Cutrera, J.1    Dibra, D.2    Xia, X.3    Hasan, A.4    Reed, S.5    Li, S.6
  • 14
    • 79951822182 scopus 로고    scopus 로고
    • Tumor vasculature targeting through NGR peptide-based drug delivery systems
    • Corti, A.; Curnis, F. Tumor vasculature targeting through NGR peptide-based drug delivery systems Curr. Pharm. Biotechnol. 2011, 12 (8) 1128-1134
    • (2011) Curr. Pharm. Biotechnol. , vol.12 , Issue.8 , pp. 1128-1134
    • Corti, A.1    Curnis, F.2
  • 15
    • 77952506765 scopus 로고    scopus 로고
    • Peptide-mediated liposomal drug delivery system targeting tumor blood vessels in anticancer therapy
    • Wu, H. C.; Chang, D. K. Peptide-mediated liposomal drug delivery system targeting tumor blood vessels in anticancer therapy J. Oncol. 2010, 2010, 723798
    • (2010) J. Oncol. , vol.2010 , pp. 723798
    • Wu, H.C.1    Chang, D.K.2
  • 16
    • 77950205585 scopus 로고    scopus 로고
    • Peptidic tumor targeting agents: The road from phage display peptide selections to clinical applications
    • Brown, K. C. Peptidic tumor targeting agents: the road from phage display peptide selections to clinical applications Curr. Pharm. Des. 2010, 16 (9) 1040-1054
    • (2010) Curr. Pharm. Des. , vol.16 , Issue.9 , pp. 1040-1054
    • Brown, K.C.1
  • 17
    • 62449200520 scopus 로고    scopus 로고
    • In vivo bacteriophage display for the discovery of novel peptide-based tumor-targeting agents
    • Newton, J. R.; Deutscher, S. L. In vivo bacteriophage display for the discovery of novel peptide-based tumor-targeting agents Methods Mol. Biol. 2009, 504, 275-290
    • (2009) Methods Mol. Biol. , vol.504 , pp. 275-290
    • Newton, J.R.1    Deutscher, S.L.2
  • 19
    • 0036063778 scopus 로고    scopus 로고
    • A tumor-homing peptide with a targeting specificity related to lymphatic vessels
    • Laakkonen, P.; Porkka, K.; Hoffman, J. A.; Ruoslahti, E. A tumor-homing peptide with a targeting specificity related to lymphatic vessels Nat. Med. 2002, 8 (7) 751-755
    • (2002) Nat. Med. , vol.8 , Issue.7 , pp. 751-755
    • Laakkonen, P.1    Porkka, K.2    Hoffman, J.A.3    Ruoslahti, E.4
  • 20
    • 0034470931 scopus 로고    scopus 로고
    • Targeting tumor vasculature with homing peptides from phage display
    • Ruoslahti, E. Targeting tumor vasculature with homing peptides from phage display Semin. Cancer Biol. 2000, 10 (6) 435-442
    • (2000) Semin. Cancer Biol. , vol.10 , Issue.6 , pp. 435-442
    • Ruoslahti, E.1
  • 23
    • 77649114060 scopus 로고    scopus 로고
    • Eph receptors and ephrins in cancer: Bidirectional signalling and beyond
    • Pasquale, E. B. Eph receptors and ephrins in cancer: bidirectional signalling and beyond Nat. Rev. Cancer 2010, 10 (3) 165-180
    • (2010) Nat. Rev. Cancer , vol.10 , Issue.3 , pp. 165-180
    • Pasquale, E.B.1
  • 24
    • 84857442694 scopus 로고    scopus 로고
    • Targeting Eph receptors with peptides and small molecules: Progress and challenges
    • [Online early access]. DOI: 10.1016/j.semcdb.2011.10.023. Published Online: Oct 25.
    • Noberini, R.; Lamberto, I.; Pasquale, E. B. Targeting Eph receptors with peptides and small molecules: progress and challenges. Semin. Cell Dev. Biol. [Online early access]. DOI: 10.1016/j.semcdb.2011.10.023. Published Online: Oct 25, 2011.
    • (2011) Semin. Cell Dev. Biol.
    • Noberini, R.1    Lamberto, I.2    Pasquale, E.B.3
  • 25
    • 18844392603 scopus 로고    scopus 로고
    • EphA2 receptor tyrosine kinase as a promising target for cancer therapeutics
    • Ireton, R. C.; Chen, J. EphA2 receptor tyrosine kinase as a promising target for cancer therapeutics Curr. Cancer Drug Targets 2005, 5 (3) 149-157
    • (2005) Curr. Cancer Drug Targets , vol.5 , Issue.3 , pp. 149-157
    • Ireton, R.C.1    Chen, J.2
  • 26
    • 57749121465 scopus 로고    scopus 로고
    • The EphA2 receptor and ephrinA1 ligand in solid tumors: Function and therapeutic targeting
    • Wykosky, J.; Debinski, W. The EphA2 receptor and ephrinA1 ligand in solid tumors: function and therapeutic targeting Mol. Cancer Res. 2008, 6 (12) 1795-1806
    • (2008) Mol. Cancer Res. , vol.6 , Issue.12 , pp. 1795-1806
    • Wykosky, J.1    Debinski, W.2
  • 28
    • 78650193841 scopus 로고    scopus 로고
    • Emerging strategies for EphA2 receptor targeting for cancer therapeutics
    • Tandon, M.; Vemula, S. V.; Mittal, S. K. Emerging strategies for EphA2 receptor targeting for cancer therapeutics Expert Opin. Ther. Targets 2011, 15 (1) 31-51
    • (2011) Expert Opin. Ther. Targets , vol.15 , Issue.1 , pp. 31-51
    • Tandon, M.1    Vemula, S.V.2    Mittal, S.K.3
  • 30
    • 37549047649 scopus 로고    scopus 로고
    • A novel, potent, and specific ephrinA1-based cytotoxin against EphA2 receptor expressing tumor cells
    • Wykosky, J.; Gibo, D. M.; Debinski, W. A novel, potent, and specific ephrinA1-based cytotoxin against EphA2 receptor expressing tumor cells Mol. Cancer Ther. 2007, 6 (12, Part 1) 3208-3218
    • (2007) Mol. Cancer Ther. , vol.6 , Issue.12 PART 1 , pp. 3208-3218
    • Wykosky, J.1    Gibo, D.M.2    Debinski, W.3
  • 31
    • 80053976962 scopus 로고    scopus 로고
    • Molecular targeting of malignant glioma cells with an EphA2-specific immunotoxin delivered by human bone marrow-derived mesenchymal stem cells
    • Sun, X. L.; Xu, Z. M.; Ke, Y. Q.; Hu, C. C.; Wang, S. Y.; Ling, G. Q.; Yan, Z. J.; Liu, Y. J.; Song, Z. H.; Jiang, X. D.; Xu, R. X. Molecular targeting of malignant glioma cells with an EphA2-specific immunotoxin delivered by human bone marrow-derived mesenchymal stem cells Cancer Lett. 2011, 312 (2) 168-177
    • (2011) Cancer Lett. , vol.312 , Issue.2 , pp. 168-177
    • Sun, X.L.1    Xu, Z.M.2    Ke, Y.Q.3    Hu, C.C.4    Wang, S.Y.5    Ling, G.Q.6    Yan, Z.J.7    Liu, Y.J.8    Song, Z.H.9    Jiang, X.D.10    Xu, R.X.11
  • 33
    • 48749085964 scopus 로고    scopus 로고
    • Magnetic nanoparticle-peptide conjugates for in vitro and in vivo targeting and extraction of cancer cells
    • Scarberry, K. E.; Dickerson, E. B.; McDonald, J. F.; Zhang, Z. J. Magnetic nanoparticle-peptide conjugates for in vitro and in vivo targeting and extraction of cancer cells J. Am. Chem. Soc. 2008, 130 (31) 10258-10262
    • (2008) J. Am. Chem. Soc. , vol.130 , Issue.31 , pp. 10258-10262
    • Scarberry, K.E.1    Dickerson, E.B.2    McDonald, J.F.3    Zhang, Z.J.4
  • 34
    • 77955252631 scopus 로고    scopus 로고
    • Structure-activity relationship analysis of peptides targeting the EphA2 receptor
    • Mitra, S.; Duggineni, S.; Koolpe, M.; Zhu, X.; Huang, Z.; Pasquale, E. B. Structure-activity relationship analysis of peptides targeting the EphA2 receptor Biochemistry 2010, 49 (31) 6687-6695
    • (2010) Biochemistry , vol.49 , Issue.31 , pp. 6687-6695
    • Mitra, S.1    Duggineni, S.2    Koolpe, M.3    Zhu, X.4    Huang, Z.5    Pasquale, E.B.6
  • 36
    • 0000096835 scopus 로고    scopus 로고
    • Click chemistry: Diverse chemical function from a few good reactions
    • Kolb, H. C.; Finn, M. G.; Sharpless, K. B. Click chemistry: diverse chemical function from a few good reactions Angew. Chem. 2001, 40 (11) 2004-2021
    • (2001) Angew. Chem. , vol.40 , Issue.11 , pp. 2004-2021
    • Kolb, H.C.1    Finn, M.G.2    Sharpless, K.B.3
  • 38
    • 33847751474 scopus 로고    scopus 로고
    • Synthesis of DOTA-conjugated multivalent cyclic-RGD peptide dendrimers via 1,3-dipolar cycloaddition and their biological evaluation: Implications for tumor targeting and tumor imaging purposes
    • Dijkgraaf, I.; Rijnders, A. Y.; Soede, A.; Dechesne, A. C.; van Esse, G. W.; Brouwer, A. J.; Corstens, F. H.; Boerman, O. C.; Rijkers, D. T.; Liskamp, R. M. Synthesis of DOTA-conjugated multivalent cyclic-RGD peptide dendrimers via 1,3-dipolar cycloaddition and their biological evaluation: implications for tumor targeting and tumor imaging purposes Org. Biomol. Chem. 2007, 5 (6) 935-944
    • (2007) Org. Biomol. Chem. , vol.5 , Issue.6 , pp. 935-944
    • Dijkgraaf, I.1    Rijnders, A.Y.2    Soede, A.3    Dechesne, A.C.4    Van Esse, G.W.5    Brouwer, A.J.6    Corstens, F.H.7    Boerman, O.C.8    Rijkers, D.T.9    Liskamp, R.M.10
  • 42
    • 33644902092 scopus 로고    scopus 로고
    • Potential clinical relevance of Eph receptors and ephrin ligands expressed in prostate carcinoma cell lines
    • Fox, B. P.; Tabone, C. J.; Kandpal, R. P. Potential clinical relevance of Eph receptors and ephrin ligands expressed in prostate carcinoma cell lines Biochem. Biophys. Res. Commun. 2006, 342 (4) 1263-1272
    • (2006) Biochem. Biophys. Res. Commun. , vol.342 , Issue.4 , pp. 1263-1272
    • Fox, B.P.1    Tabone, C.J.2    Kandpal, R.P.3
  • 43
    • 26444553595 scopus 로고    scopus 로고
    • Hypoxia up-regulates expression of Eph receptors and ephrins in mouse skin
    • Vihanto, M. M.; Plock, J.; Erni, D.; Frey, B. M.; Frey, F. J.; Huynh-Do, U. Hypoxia up-regulates expression of Eph receptors and ephrins in mouse skin FASEB J. 2005, 19 (12) 1689-1691
    • (2005) FASEB J. , vol.19 , Issue.12 , pp. 1689-1691
    • Vihanto, M.M.1    Plock, J.2    Erni, D.3    Frey, B.M.4    Frey, F.J.5    Huynh-Do, U.6
  • 44
    • 79960805268 scopus 로고    scopus 로고
    • Enabling anticancer therapeutics by nanoparticle carriers: The delivery of paclitaxel
    • Liu, Y.; Zhang, B.; Yan, B. Enabling anticancer therapeutics by nanoparticle carriers: the delivery of paclitaxel Int. J. Mol. Sci. 2011, 12 (7) 4395-4413
    • (2011) Int. J. Mol. Sci. , vol.12 , Issue.7 , pp. 4395-4413
    • Liu, Y.1    Zhang, B.2    Yan, B.3
  • 45
    • 72449143090 scopus 로고    scopus 로고
    • Paclitaxel in cancer treatment: Perspectives and prospects of its delivery challenges
    • Singh, S.; Dash, A. K. Paclitaxel in cancer treatment: perspectives and prospects of its delivery challenges Crit. Rev. Ther. Drug Carrier Syst. 2009, 26 (4) 333-372
    • (2009) Crit. Rev. Ther. Drug Carrier Syst. , vol.26 , Issue.4 , pp. 333-372
    • Singh, S.1    Dash, A.K.2
  • 47
    • 83755171604 scopus 로고    scopus 로고
    • EphrinA1-EphA2 signal induces compaction and polarization of Madin-Darby canine kidney cells by inactivating ezrin through negative regulation of RhoA
    • Wakayama, Y.; Miura, K.; Sabe, H.; Mochizuki, N. EphrinA1-EphA2 signal induces compaction and polarization of Madin-Darby canine kidney cells by inactivating ezrin through negative regulation of RhoA J. Biol. Chem. 2011, 286, 44243-44253
    • (2011) J. Biol. Chem. , vol.286 , pp. 44243-44253
    • Wakayama, Y.1    Miura, K.2    Sabe, H.3    Mochizuki, N.4
  • 48
    • 65249147216 scopus 로고    scopus 로고
    • EphA2 engages Git1 to suppress Arf6 activity modulating epithelial cell-cell contacts
    • Miura, K.; Nam, J. M.; Kojima, C.; Mochizuki, N.; Sabe, H. EphA2 engages Git1 to suppress Arf6 activity modulating epithelial cell-cell contacts Mol. Biol. Cell 2009, 20 (7) 1949-1959
    • (2009) Mol. Biol. Cell , vol.20 , Issue.7 , pp. 1949-1959
    • Miura, K.1    Nam, J.M.2    Kojima, C.3    Mochizuki, N.4    Sabe, H.5
  • 49
    • 0034581176 scopus 로고    scopus 로고
    • Alkaline phosphatase fusions of ligands or receptors as in situ probes for staining of cells, tissues, and embryos
    • Flanagan, J. G.; Cheng, H. J.; Feldheim, D. A.; Hattori, M.; Lu, Q.; Vanderhaeghen, P. Alkaline phosphatase fusions of ligands or receptors as in situ probes for staining of cells, tissues, and embryos Methods Enzymol. 2000, 327, 19-35
    • (2000) Methods Enzymol. , vol.327 , pp. 19-35
    • Flanagan, J.G.1    Cheng, H.J.2    Feldheim, D.A.3    Hattori, M.4    Lu, Q.5    Vanderhaeghen, P.6
  • 50
    • 0024245391 scopus 로고
    • Isolation and characterization of human lysosomal membrane glycoproteins, h-lamp-1 and h-lamp-2. Major sialoglycoproteins carrying polylactosaminoglycan
    • Carlsson, S. R.; Roth, J.; Piller, F.; Fukuda, M. Isolation and characterization of human lysosomal membrane glycoproteins, h-lamp-1 and h-lamp-2. Major sialoglycoproteins carrying polylactosaminoglycan J. Biol. Chem. 1988, 263 (35) 18911-18919
    • (1988) J. Biol. Chem. , vol.263 , Issue.35 , pp. 18911-18919
    • Carlsson, S.R.1    Roth, J.2    Piller, F.3    Fukuda, M.4
  • 51
    • 79953719297 scopus 로고    scopus 로고
    • A survey of the anti-apoptotic Bcl-2 subfamily expression in cancer types provides a platform to predict the efficacy of Bcl-2 antagonists in cancer therapy
    • Placzek, W. J.; Wei, J.; Kitada, S.; Zhai, D.; Reed, J. C.; Pellecchia, M. A survey of the anti-apoptotic Bcl-2 subfamily expression in cancer types provides a platform to predict the efficacy of Bcl-2 antagonists in cancer therapy Cell Death Dis. 2010, 1, e40
    • (2010) Cell Death Dis. , vol.1 , pp. 40
    • Placzek, W.J.1    Wei, J.2    Kitada, S.3    Zhai, D.4    Reed, J.C.5    Pellecchia, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.