HTS by NMR of combinatorial libraries: A fragment-based approach to ligand discovery

Chemistry and Biology

Volumn 20, Issue 1, 2013, Pages 19-33

  Wu, Bainan ^a   Zhang, Ziming ^a   Noberini, Roberta ^a   Barile, Elisa ^a   Giulianotti, Marc ^b   Pinilla, Clemencia ^b   Houghten, Richard A ^b   Pasquale, Elena B ^a   Pellecchia, Maurizio ^a  

^a BURNHAM INSTITUTE   (United States)

^b TORREY PINES INSTITUTE FOR MOLECULAR STUDIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIR3 PROTEIN; PROTEIN; UNCLASSIFIED DRUG; X LINKED INHIBITOR OF APOPTOSIS;

ARTICLE; COMBINATORIAL CHEMISTRY; CONTROLLED STUDY; HIGH THROUGHPUT SCREENING; IC 50; NUCLEAR MAGNETIC RESONANCE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN PROTEIN INTERACTION; STRUCTURE ACTIVITY RELATION;

COMBINATORIAL CHEMISTRY TECHNIQUES; DRUG DESIGN; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; LIGANDS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; PROTEIN STRUCTURE, TERTIARY; RECEPTOR, EPHA4; SMALL MOLECULE LIBRARIES; STRUCTURE-ACTIVITY RELATIONSHIP; X-LINKED INHIBITOR OF APOPTOSIS PROTEIN;

EID: 84872928524     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chembiol.2012.10.015     Document Type: Article

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