-
1
-
-
0035902180
-
Oncogenic kinase signalling
-
Blume-Jensen P., Hunter T. Oncogenic kinase signalling. Nature 2001, 411(6835):355-365.
-
(2001)
Nature
, vol.411
, Issue.6835
, pp. 355-365
-
-
Blume-Jensen, P.1
Hunter, T.2
-
2
-
-
63749113783
-
Tyrosine phosphorylation: thirty years and counting
-
Hunter T. Tyrosine phosphorylation: thirty years and counting. Curr Opin Cell Biol 2009, 21(2):140-146.
-
(2009)
Curr Opin Cell Biol
, vol.21
, Issue.2
, pp. 140-146
-
-
Hunter, T.1
-
3
-
-
77953896432
-
Cell signaling by receptor tyrosine kinases
-
Lemmon M.A., Schlessinger J. Cell signaling by receptor tyrosine kinases. Cell 2010, 141(7):1117-1134.
-
(2010)
Cell
, vol.141
, Issue.7
, pp. 1117-1134
-
-
Lemmon, M.A.1
Schlessinger, J.2
-
4
-
-
0036303033
-
Mechanisms and functions of Eph and ephrin signalling
-
Kullander K., Klein R. Mechanisms and functions of Eph and ephrin signalling. Nat Rev Mol Cell Biol 2002, 3(7):475-486.
-
(2002)
Nat Rev Mol Cell Biol
, vol.3
, Issue.7
, pp. 475-486
-
-
Kullander, K.1
Klein, R.2
-
5
-
-
11244299992
-
Ephrin signaling in vivo: look both ways
-
Davy A., Soriano P. Ephrin signaling in vivo: look both ways. Dev Dyn 2005, 232(1):1-10.
-
(2005)
Dev Dyn
, vol.232
, Issue.1
, pp. 1-10
-
-
Davy, A.1
Soriano, P.2
-
6
-
-
41149084179
-
Eph-ephrin bidirectional signaling in physiology and disease
-
Pasquale E.B. Eph-ephrin bidirectional signaling in physiology and disease. Cell 2008, 133(1):38-52.
-
(2008)
Cell
, vol.133
, Issue.1
, pp. 38-52
-
-
Pasquale, E.B.1
-
7
-
-
5044240692
-
Diverse roles of Eph receptors and ephrins in the regulation of cell migration and tissue assembly
-
Poliakov A., Cotrina M., Wilkinson D.G. Diverse roles of Eph receptors and ephrins in the regulation of cell migration and tissue assembly. Dev Cell 2004, 7(4):465-480.
-
(2004)
Dev Cell
, vol.7
, Issue.4
, pp. 465-480
-
-
Poliakov, A.1
Cotrina, M.2
Wilkinson, D.G.3
-
8
-
-
48849108415
-
Eph, a protein family coming of age: more confusion, insight, or complexity?
-
Lackmann M., Boyd A.W. Eph, a protein family coming of age: more confusion, insight, or complexity?. Sci Signal 2008, 1(15):re2.
-
(2008)
Sci Signal
, vol.1
, Issue.15
-
-
Lackmann, M.1
Boyd, A.W.2
-
9
-
-
51349144056
-
Eph/ephrin signalling and function in oncogenesis: lessons from embryonic development
-
Janes P.W., Adikari S., Lackmann M. Eph/ephrin signalling and function in oncogenesis: lessons from embryonic development. Curr Cancer Drug Targets 2008, 8(6):473-479.
-
(2008)
Curr Cancer Drug Targets
, vol.8
, Issue.6
, pp. 473-479
-
-
Janes, P.W.1
Adikari, S.2
Lackmann, M.3
-
10
-
-
77649114060
-
Eph receptors and ephrins in cancer: bidirectional signalling and beyond
-
Pasquale E.B. Eph receptors and ephrins in cancer: bidirectional signalling and beyond. Nat Rev Cancer 2010, 10(3):165-180.
-
(2010)
Nat Rev Cancer
, vol.10
, Issue.3
, pp. 165-180
-
-
Pasquale, E.B.1
-
11
-
-
0036568740
-
Ephrins are not only unattractive
-
Holmberg J., Frisen J. Ephrins are not only unattractive. Trends Neurosci 2002, 25(5):239-243.
-
(2002)
Trends Neurosci
, vol.25
, Issue.5
, pp. 239-243
-
-
Holmberg, J.1
Frisen, J.2
-
12
-
-
33748302057
-
Repulsion or adhesion: receptors make the call
-
Halloran M.C., Wolman M.A. Repulsion or adhesion: receptors make the call. Curr Opin Cell Biol 2006, 18(5):533-540.
-
(2006)
Curr Opin Cell Biol
, vol.18
, Issue.5
, pp. 533-540
-
-
Halloran, M.C.1
Wolman, M.A.2
-
13
-
-
15744403216
-
Eph receptors: two ways to sharpen boundaries
-
Sela-Donenfeld D., Wilkinson D.G. Eph receptors: two ways to sharpen boundaries. Curr Biol 2005, 15(6):R210-R212.
-
(2005)
Curr Biol
, vol.15
, Issue.6
-
-
Sela-Donenfeld, D.1
Wilkinson, D.G.2
-
14
-
-
33847718707
-
Dynamic control of signaling by modular adaptor proteins
-
Pawson T. Dynamic control of signaling by modular adaptor proteins. Curr Opin Cell Biol 2007, 19(2):112-116.
-
(2007)
Curr Opin Cell Biol
, vol.19
, Issue.2
, pp. 112-116
-
-
Pawson, T.1
-
15
-
-
25144472138
-
Eph receptor signalling; dimerisation just isn't enough
-
Vearing C.J., Lackmann M. Eph receptor signalling; dimerisation just isn't enough. Growth Factors 2005, 23(1):67-76.
-
(2005)
Growth Factors
, vol.23
, Issue.1
, pp. 67-76
-
-
Vearing, C.J.1
Lackmann, M.2
-
16
-
-
0031559401
-
Unified nomenclature for Eph family receptors and their ligands, the ephrins
-
Eph Nomenclature Committee
-
Unified nomenclature for Eph family receptors and their ligands, the ephrins. Cell 1997, 90:403-404. Eph Nomenclature Committee.
-
(1997)
Cell
, vol.90
, pp. 403-404
-
-
-
17
-
-
15844429889
-
Eph receptors and ligands comprise two major specificity subclasses and are reciprocally compartmentalized during embryogenesis
-
Gale N.W., Holland S.J., Valenzuela D.M., Flenniken A., Pan L., Ryan T.E., et al. Eph receptors and ligands comprise two major specificity subclasses and are reciprocally compartmentalized during embryogenesis. Neuron 1996, 17(1):9-19.
-
(1996)
Neuron
, vol.17
, Issue.1
, pp. 9-19
-
-
Gale, N.W.1
Holland, S.J.2
Valenzuela, D.M.3
Flenniken, A.4
Pan, L.5
Ryan, T.E.6
-
18
-
-
0037459382
-
Role of EphA4 and EphrinB3 in local neuronal circuits that control walking
-
Kullander K., Butt S.J., Lebret J.M., Lundfald L., Restrepo C.E., Rydström A., et al. Role of EphA4 and EphrinB3 in local neuronal circuits that control walking. Science 2003, 299(5614):1889-1892.
-
(2003)
Science
, vol.299
, Issue.5614
, pp. 1889-1892
-
-
Kullander, K.1
Butt, S.J.2
Lebret, J.M.3
Lundfald, L.4
Restrepo, C.E.5
Rydström, A.6
-
19
-
-
0035312946
-
Ephrin-B3 is the midline barrier that prevents corticospinal tract axons from recrossing: allowing for unilateral motor control
-
Kullander K., Croll S.D., Zimmer M., Pan L., McClain J., Hughes V., et al. Ephrin-B3 is the midline barrier that prevents corticospinal tract axons from recrossing: allowing for unilateral motor control. Genes Dev 2001, 15(7):877-888.
-
(2001)
Genes Dev
, vol.15
, Issue.7
, pp. 877-888
-
-
Kullander, K.1
Croll, S.D.2
Zimmer, M.3
Pan, L.4
McClain, J.5
Hughes, V.6
-
20
-
-
11144354644
-
Repelling class discrimination: ephrin-A5 binds to and activates EphB2 receptor signaling
-
Himanen J.P., Chumley M.J., Lackmann M., Li C., Barton W.A., Jeffrey P.D., et al. Repelling class discrimination: ephrin-A5 binds to and activates EphB2 receptor signaling. Nat Neurosci 2004, 7(5):501-509.
-
(2004)
Nat Neurosci
, vol.7
, Issue.5
, pp. 501-509
-
-
Himanen, J.P.1
Chumley, M.J.2
Lackmann, M.3
Li, C.4
Barton, W.A.5
Jeffrey, P.D.6
-
21
-
-
84857444444
-
Ectodomain structures of Eph receptors
-
(1096-3634) [Epub ahead of print Oct 24, 2011]
-
Himanen J.P. Ectodomain structures of Eph receptors. Semin Cell Dev Biol 2011, (1096-3634) [Epub ahead of print Oct 24, 2011].
-
(2011)
Semin Cell Dev Biol
-
-
Himanen, J.P.1
-
22
-
-
77954627688
-
Architecture of Eph receptor clusters
-
Himanen J.P., Yermekbayeva L., Janes P.W., Walker J.R., Xu K., Atapattu L., et al. Architecture of Eph receptor clusters. Proc Natl Acad Sci USA 2010, 107(24):10860-10865.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, Issue.24
, pp. 10860-10865
-
-
Himanen, J.P.1
Yermekbayeva, L.2
Janes, P.W.3
Walker, J.R.4
Xu, K.5
Atapattu, L.6
-
23
-
-
77950516909
-
An extracellular steric seeding mechanism for Eph-ephrin signaling platform assembly
-
Seiradake E., Harlos K., Sutton G., Aricescu A.R., Jones E.Y. An extracellular steric seeding mechanism for Eph-ephrin signaling platform assembly. Nat Struct Mol Biol 2010, 17(4):398-402.
-
(2010)
Nat Struct Mol Biol
, vol.17
, Issue.4
, pp. 398-402
-
-
Seiradake, E.1
Harlos, K.2
Sutton, G.3
Aricescu, A.R.4
Jones, E.Y.5
-
24
-
-
0028110068
-
Ligands for EPH-related receptor tyrosine kinases that require membrane attachment or clustering for activity
-
Davis S., Gale N.W., Aldrich T.H., Maisonpierre P.C., Lhotak V., Pawson T., et al. Ligands for EPH-related receptor tyrosine kinases that require membrane attachment or clustering for activity. Science 1994, 266(5186):816-819.
-
(1994)
Science
, vol.266
, Issue.5186
, pp. 816-819
-
-
Davis, S.1
Gale, N.W.2
Aldrich, T.H.3
Maisonpierre, P.C.4
Lhotak, V.5
Pawson, T.6
-
25
-
-
0036045804
-
EphrinA1-induced cytoskeletal re-organization requires FAK and p130(cas)
-
Carter N., Nakamoto T., Hirai H., Hunter T. EphrinA1-induced cytoskeletal re-organization requires FAK and p130(cas). Nat Cell Biol 2002, 4(8):565-573.
-
(2002)
Nat Cell Biol
, vol.4
, Issue.8
, pp. 565-573
-
-
Carter, N.1
Nakamoto, T.2
Hirai, H.3
Hunter, T.4
-
26
-
-
0842282623
-
Antiangiogenic and antitumor efficacy of EphA2 receptor antagonist
-
Dobrzanski P., Hunter K., Jones-Bolin S., Chang H., Robinson C., Pritchard S., et al. Antiangiogenic and antitumor efficacy of EphA2 receptor antagonist. Cancer Res 2004, 64(3):910-919.
-
(2004)
Cancer Res
, vol.64
, Issue.3
, pp. 910-919
-
-
Dobrzanski, P.1
Hunter, K.2
Jones-Bolin, S.3
Chang, H.4
Robinson, C.5
Pritchard, S.6
-
27
-
-
0032493828
-
Distinct subdomains of the EphA3 receptor mediate ligand binding and receptor dimerization
-
Lackmann M., Oates A.C., Dottori M., Smith F.M., Do C., Power M., et al. Distinct subdomains of the EphA3 receptor mediate ligand binding and receptor dimerization. J Biol Chem 1998, 273(32):20228-20237.
-
(1998)
J Biol Chem
, vol.273
, Issue.32
, pp. 20228-20237
-
-
Lackmann, M.1
Oates, A.C.2
Dottori, M.3
Smith, F.M.4
Do, C.5
Power, M.6
-
28
-
-
0036500192
-
Ephrin-A5 induces rounding, blebbing and de-adhesion of EphA3-expressing 293T and melanoma cells by CrkII and Rho-mediated signalling
-
Lawrenson I.D., Wimmer-Kleikamp S.H., Lock P., Schoenwaelder S.M., Down M., Boyd A.W., et al. Ephrin-A5 induces rounding, blebbing and de-adhesion of EphA3-expressing 293T and melanoma cells by CrkII and Rho-mediated signalling. J Cell Sci 2002, 115(Pt 5):1059-1072.
-
(2002)
J Cell Sci
, vol.115
, Issue.PART 5
, pp. 1059-1072
-
-
Lawrenson, I.D.1
Wimmer-Kleikamp, S.H.2
Lock, P.3
Schoenwaelder, S.M.4
Down, M.5
Boyd, A.W.6
-
29
-
-
17044377138
-
Coexpressed EphA receptors and ephrin-A ligands mediate opposing actions on growth cone navigation from distinct membrane domains
-
Marquardt T., Shirasaki R., Ghosh S., Andrews S.E., Carter N., Hunter T., et al. Coexpressed EphA receptors and ephrin-A ligands mediate opposing actions on growth cone navigation from distinct membrane domains. Cell 2005, 121(1):127-139.
-
(2005)
Cell
, vol.121
, Issue.1
, pp. 127-139
-
-
Marquardt, T.1
Shirasaki, R.2
Ghosh, S.3
Andrews, S.E.4
Carter, N.5
Hunter, T.6
-
30
-
-
0242352659
-
Ephrin signaling: one raft to rule them all? One raft to sort them? One raft to spread their call and in signaling bind them?
-
Gauthier L.R., Robbins S.M. Ephrin signaling: one raft to rule them all? One raft to sort them? One raft to spread their call and in signaling bind them?. Life Sci 2003, 74(2-3):207-216.
-
(2003)
Life Sci
, vol.74
, Issue.2-3
, pp. 207-216
-
-
Gauthier, L.R.1
Robbins, S.M.2
-
31
-
-
0032031705
-
Eph receptors discriminate specific ligand oligomers to determine alternative signaling complexes: attachment, and assembly responses
-
Stein E., Lane A.A., Cerretti D.P., Schoecklmann H.O., Schroff A.D., Van Etten R.L., et al. Eph receptors discriminate specific ligand oligomers to determine alternative signaling complexes: attachment, and assembly responses. Genes Dev 1998, 12(5):667-678.
-
(1998)
Genes Dev
, vol.12
, Issue.5
, pp. 667-678
-
-
Stein, E.1
Lane, A.A.2
Cerretti, D.P.3
Schoecklmann, H.O.4
Schroff, A.D.5
Van Etten, R.L.6
-
32
-
-
0035924322
-
Crystal structure of an Eph receptor-ephrin complex
-
Himanen J.P., Rajashankar K.R., Lackmann M., Cowan C.A., Henkemeyer M., Nikolov D.B., et al. Crystal structure of an Eph receptor-ephrin complex. Nature 2001, 414(6866):933-938.
-
(2001)
Nature
, vol.414
, Issue.6866
, pp. 933-938
-
-
Himanen, J.P.1
Rajashankar, K.R.2
Lackmann, M.3
Cowan, C.A.4
Henkemeyer, M.5
Nikolov, D.B.6
-
33
-
-
0035846705
-
Signals from Eph and ephrin proteins: a developmental tool kit
-
Boyd A.W., Lackmann M. Signals from Eph and ephrin proteins: a developmental tool kit. Sci STKE 2001, 2001(112):RE20.
-
(2001)
Sci STKE
, vol.2001
, Issue.112
-
-
Boyd, A.W.1
Lackmann, M.2
-
34
-
-
7244245371
-
A relative signalling model for the formation of a topographic neural map
-
Reber M., Burrola P., Lemke G. A relative signalling model for the formation of a topographic neural map. Nature 2004, 431(7010):847-853.
-
(2004)
Nature
, vol.431
, Issue.7010
, pp. 847-853
-
-
Reber, M.1
Burrola, P.2
Lemke, G.3
-
35
-
-
28444498874
-
Retinotectal mapping: new insights from molecular genetics
-
Lemke G., Reber M. Retinotectal mapping: new insights from molecular genetics. Annu Rev Cell Dev Biol 2005, 21:551-580.
-
(2005)
Annu Rev Cell Dev Biol
, vol.21
, pp. 551-580
-
-
Lemke, G.1
Reber, M.2
-
37
-
-
70249086591
-
Ephrin-independent regulation of cell substrate adhesion by the EphB4 receptor
-
Noren N.K., Yang N.Y., Silldorff M., Mutyala R., Pasquale E.B. Ephrin-independent regulation of cell substrate adhesion by the EphB4 receptor. Biochem J 2009, 422(3):433-442.
-
(2009)
Biochem J
, vol.422
, Issue.3
, pp. 433-442
-
-
Noren, N.K.1
Yang, N.Y.2
Silldorff, M.3
Mutyala, R.4
Pasquale, E.B.5
-
38
-
-
0037450709
-
Association of Dishevelled with Eph tyrosine kinase receptor and ephrin mediates cell repulsion
-
Tanaka M., Kamo T., Ota S., Sugimura H. Association of Dishevelled with Eph tyrosine kinase receptor and ephrin mediates cell repulsion. EMBO J 2003, 22(4):847-858.
-
(2003)
EMBO J
, vol.22
, Issue.4
, pp. 847-858
-
-
Tanaka, M.1
Kamo, T.2
Ota, S.3
Sugimura, H.4
-
39
-
-
0028170817
-
Receptor protein-tyrosine kinases and their signal transduction pathways
-
van der Geer P., Hunter T., Lindberg R.A. Receptor protein-tyrosine kinases and their signal transduction pathways. Annu Rev Cell Biol 1994, 10:251-337.
-
(1994)
Annu Rev Cell Biol
, vol.10
, pp. 251-337
-
-
van der Geer, P.1
Hunter, T.2
Lindberg, R.A.3
-
40
-
-
0030923341
-
Ligand for EPH-related kinase (LERK) 7 is the preferred high affinity ligand for the HEK receptor
-
Lackmann M., Mann R.J., Kravets L., Smith F.M., Bucci T.A., Maxwell K.F., et al. Ligand for EPH-related kinase (LERK) 7 is the preferred high affinity ligand for the HEK receptor. J Biol Chem 1997, 272(26):16521-16530.
-
(1997)
J Biol Chem
, vol.272
, Issue.26
, pp. 16521-16530
-
-
Lackmann, M.1
Mann, R.J.2
Kravets, L.3
Smith, F.M.4
Bucci, T.A.5
Maxwell, K.F.6
-
41
-
-
1442358805
-
Recruitment of Eph receptors into signaling clusters does not require ephrin contact
-
Wimmer-Kleikamp S.H., Janes P.W., Squire A., Bastiaens P.I., Lackmann M. Recruitment of Eph receptors into signaling clusters does not require ephrin contact. J Cell Biol 2004, 164(5):661-666.
-
(2004)
J Cell Biol
, vol.164
, Issue.5
, pp. 661-666
-
-
Wimmer-Kleikamp, S.H.1
Janes, P.W.2
Squire, A.3
Bastiaens, P.I.4
Lackmann, M.5
-
42
-
-
22544434364
-
Three distinct molecular surfaces in ephrin-A5 are essential for a functional interaction with EphA3
-
Day B., To C., Himanen J.P., Smith F.M., Nikolov D.B., Boyd A.W., et al. Three distinct molecular surfaces in ephrin-A5 are essential for a functional interaction with EphA3. J Biol Chem 2005, 280(28):26526-26532.
-
(2005)
J Biol Chem
, vol.280
, Issue.28
, pp. 26526-26532
-
-
Day, B.1
To, C.2
Himanen, J.P.3
Smith, F.M.4
Nikolov, D.B.5
Boyd, A.W.6
-
43
-
-
1542364449
-
Dissecting the EphA3/Ephrin-A5 interactions using a novel functional mutagenesis screen
-
Smith F.M., Vearing C., Lackmann M., Treutlein H., Himanen J., Chen K., et al. Dissecting the EphA3/Ephrin-A5 interactions using a novel functional mutagenesis screen. J Biol Chem 2004, 279(10):9522-9531.
-
(2004)
J Biol Chem
, vol.279
, Issue.10
, pp. 9522-9531
-
-
Smith, F.M.1
Vearing, C.2
Lackmann, M.3
Treutlein, H.4
Himanen, J.5
Chen, K.6
-
44
-
-
59749092842
-
Structure of the ligand-binding domain of the EphB2 receptor at 2 A resolution
-
Goldgur Y., Paavilainen S., Nikolov D., Himanen J.P. Structure of the ligand-binding domain of the EphB2 receptor at 2 A resolution. Acta Crystallogr Sect F Struct Biol Cryst Commun 2009, 65(Pt 2):71-74.
-
(2009)
Acta Crystallogr Sect F Struct Biol Cryst Commun
, vol.65
, Issue.PART 2
, pp. 71-74
-
-
Goldgur, Y.1
Paavilainen, S.2
Nikolov, D.3
Himanen, J.P.4
-
45
-
-
77956262547
-
Crystal structure of the ligand-binding domain of the promiscuous EphA4 receptor reveals two distinct conformations
-
Singla N., Goldgur Y., Xu K., Paavilainen S., Nikolov D.B., Himanen J.P. Crystal structure of the ligand-binding domain of the promiscuous EphA4 receptor reveals two distinct conformations. Biochem Biophys Res Commun 2010, 399(4):555-559.
-
(2010)
Biochem Biophys Res Commun
, vol.399
, Issue.4
, pp. 555-559
-
-
Singla, N.1
Goldgur, Y.2
Xu, K.3
Paavilainen, S.4
Nikolov, D.B.5
Himanen, J.P.6
-
46
-
-
0032968502
-
An early developmental role for Eph-ephrin interaction during vertebrate gastrulation
-
Oates A.C., Lackmann M., Power M.A., Brennan C., Down L.M., Do C., et al. An early developmental role for Eph-ephrin interaction during vertebrate gastrulation. Mech Dev 1999, 83(1-2):77-94.
-
(1999)
Mech Dev
, vol.83
, Issue.1-2
, pp. 77-94
-
-
Oates, A.C.1
Lackmann, M.2
Power, M.A.3
Brennan, C.4
Down, L.M.5
Do, C.6
-
47
-
-
33344477193
-
Silencing of EphA3 through a cis interaction with ephrinA5
-
Carvalho R.F., Beutler M., Marler K.J., Knöll B., Becker-Barroso E., Heintzmann R., et al. Silencing of EphA3 through a cis interaction with ephrinA5. Nat Neurosci 2006, 9(3):322-330.
-
(2006)
Nat Neurosci
, vol.9
, Issue.3
, pp. 322-330
-
-
Carvalho, R.F.1
Beutler, M.2
Marler, K.J.3
Knöll, B.4
Becker-Barroso, E.5
Heintzmann, R.6
-
48
-
-
79960153609
-
Ephrin-mediated cis-attenuation of Eph receptor signaling is essential for spinal motor axon guidance
-
Kao T.J., Kania A. Ephrin-mediated cis-attenuation of Eph receptor signaling is essential for spinal motor axon guidance. Neuron 2011, 71(1):76-91.
-
(2011)
Neuron
, vol.71
, Issue.1
, pp. 76-91
-
-
Kao, T.J.1
Kania, A.2
-
49
-
-
73349087177
-
The single transmembrane domains of human receptor tyrosine kinases encode self-interactions
-
Finger C., Escher C., Schneider D. The single transmembrane domains of human receptor tyrosine kinases encode self-interactions. Sci Signal 2009, 2(89):ra56.
-
(2009)
Sci Signal
, vol.2
, Issue.89
-
-
Finger, C.1
Escher, C.2
Schneider, D.3
-
50
-
-
18744378545
-
A putative molecular-activation switch in the transmembrane domain of erbB2
-
Fleishman S.J., Schlessinger J., Ben-Tal N. A putative molecular-activation switch in the transmembrane domain of erbB2. Proc Natl Acad Sci USA 2002, 99(25):15937-15940.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, Issue.25
, pp. 15937-15940
-
-
Fleishman, S.J.1
Schlessinger, J.2
Ben-Tal, N.3
-
51
-
-
0035979763
-
Activation of preformed EGF receptor dimers by ligand-induced rotation of the transmembrane domain
-
Moriki T., Maruyama H., Maruyama I.N. Activation of preformed EGF receptor dimers by ligand-induced rotation of the transmembrane domain. J Mol Biol 2001, 311(5):1011-1026.
-
(2001)
J Mol Biol
, vol.311
, Issue.5
, pp. 1011-1026
-
-
Moriki, T.1
Maruyama, H.2
Maruyama, I.N.3
-
52
-
-
57649221018
-
Spatial structure and pH-dependent conformational diversity of dimeric transmembrane domain of the receptor tyrosine kinase EphA1
-
Bocharov E.V., Mayzel M.L., Volynsky P.E., Goncharuk M.V., Ermolyuk Y.S., Schulga A.A., et al. Spatial structure and pH-dependent conformational diversity of dimeric transmembrane domain of the receptor tyrosine kinase EphA1. J Biol Chem 2008, 283(43):29385-29395.
-
(2008)
J Biol Chem
, vol.283
, Issue.43
, pp. 29385-29395
-
-
Bocharov, E.V.1
Mayzel, M.L.2
Volynsky, P.E.3
Goncharuk, M.V.4
Ermolyuk, Y.S.5
Schulga, A.A.6
-
53
-
-
77749318504
-
Left-handed dimer of EphA2 transmembrane domain: helix packing diversity among receptor tyrosine kinases
-
Bocharov E.V., Mayzel M.L., Volynsky P.E., Mineev K.S., Tkach E.N., Ermolyuk Y.S., et al. Left-handed dimer of EphA2 transmembrane domain: helix packing diversity among receptor tyrosine kinases. Biophys J 2010, 98(5):881-889.
-
(2010)
Biophys J
, vol.98
, Issue.5
, pp. 881-889
-
-
Bocharov, E.V.1
Mayzel, M.L.2
Volynsky, P.E.3
Mineev, K.S.4
Tkach, E.N.5
Ermolyuk, Y.S.6
-
54
-
-
30344442873
-
The many faces of SAM
-
Qiao F., Bowie J.U. The many faces of SAM. Sci STKE 2005, 2005(286):re7.
-
(2005)
Sci STKE
, vol.2005
, Issue.286
-
-
Qiao, F.1
Bowie, J.U.2
-
55
-
-
0032881609
-
Solution structure of the receptor tyrosine kinase EphB2 SAM domain and identification of two distinct homotypic interaction sites
-
Smalla M., Schmieder P., Kelly M., Ter Laak A., Krause G., Ball L., et al. Solution structure of the receptor tyrosine kinase EphB2 SAM domain and identification of two distinct homotypic interaction sites. Protein Sci 1999, 8(10):1954-1961.
-
(1999)
Protein Sci
, vol.8
, Issue.10
, pp. 1954-1961
-
-
Smalla, M.1
Schmieder, P.2
Kelly, M.3
Ter Laak, A.4
Krause, G.5
Ball, L.6
-
56
-
-
0033601216
-
Monomeric structure of the human EphB2 sterile alpha motif domain
-
Thanos C.D., Faham S., Goodwill K.E., Cascio D., Phillips M., Bowie J.U. Monomeric structure of the human EphB2 sterile alpha motif domain. J Biol Chem 1999, 274(52):37301-37306.
-
(1999)
J Biol Chem
, vol.274
, Issue.52
, pp. 37301-37306
-
-
Thanos, C.D.1
Faham, S.2
Goodwill, K.E.3
Cascio, D.4
Phillips, M.5
Bowie, J.U.6
-
57
-
-
0032948019
-
The crystal structure of an Eph receptor SAM domain reveals a mechanism for modular dimerization
-
Stapleton D., Balan I., Pawson T., Sicheri F. The crystal structure of an Eph receptor SAM domain reveals a mechanism for modular dimerization. Nat Struct Biol 1999, 6(1):44-49.
-
(1999)
Nat Struct Biol
, vol.6
, Issue.1
, pp. 44-49
-
-
Stapleton, D.1
Balan, I.2
Pawson, T.3
Sicheri, F.4
-
58
-
-
34047268925
-
Regulation of EphA2 receptor endocytosis by SHIP2 lipid phosphatase via phosphatidyl inositol 3-kinase-dependent Rac1 activation
-
Zhuang G., Hunter S., Hwang Y., Chen J. Regulation of EphA2 receptor endocytosis by SHIP2 lipid phosphatase via phosphatidyl inositol 3-kinase-dependent Rac1 activation. J Biol Chem 2007, 282(4):2683-2694.
-
(2007)
J Biol Chem
, vol.282
, Issue.4
, pp. 2683-2694
-
-
Zhuang, G.1
Hunter, S.2
Hwang, Y.3
Chen, J.4
-
59
-
-
61949271115
-
EphA1 interacts with integrin-linked kinase and regulates cell morphology and motility
-
Yamazaki T., Masuda J., Omori T., Usui R., Akiyama H., Maru Y. EphA1 interacts with integrin-linked kinase and regulates cell morphology and motility. J Cell Sci 2009, 122(2):243-255.
-
(2009)
J Cell Sci
, vol.122
, Issue.2
, pp. 243-255
-
-
Yamazaki, T.1
Masuda, J.2
Omori, T.3
Usui, R.4
Akiyama, H.5
Maru, Y.6
-
60
-
-
0029813872
-
Ligand activation of ELK receptor tyrosine kinase promotes its association with Grb10 and Grb2 in vascular endothelial cells
-
Stein E., Cerretti D.P., Daniel T.O. Ligand activation of ELK receptor tyrosine kinase promotes its association with Grb10 and Grb2 in vascular endothelial cells. J Biol Chem 1996, 271(38):23588-23593.
-
(1996)
J Biol Chem
, vol.271
, Issue.38
, pp. 23588-23593
-
-
Stein, E.1
Cerretti, D.P.2
Daniel, T.O.3
-
61
-
-
47049106661
-
Identification and functional analysis of phosphorylated tyrosine residues within EphA2 receptor tyrosine kinase
-
Fang W.B., Brantley-Sieders D.M., Hwang Y., Ham A.J., Chen J. Identification and functional analysis of phosphorylated tyrosine residues within EphA2 receptor tyrosine kinase. J Biol Chem 2008, 283(23):16017-16026.
-
(2008)
J Biol Chem
, vol.283
, Issue.23
, pp. 16017-16026
-
-
Fang, W.B.1
Brantley-Sieders, D.M.2
Hwang, Y.3
Ham, A.J.4
Chen, J.5
-
62
-
-
1842828975
-
Eph receptor-ephrin bidirectional signals that target Ras and Rho proteins
-
Noren N.K., Pasquale E.B. Eph receptor-ephrin bidirectional signals that target Ras and Rho proteins. Cell Signal 2004, 16(6):655-666.
-
(2004)
Cell Signal
, vol.16
, Issue.6
, pp. 655-666
-
-
Noren, N.K.1
Pasquale, E.B.2
-
63
-
-
0033966557
-
Nck-interacting Ste20 kinase couples Eph receptors to c-Jun N-terminal kinase and integrin activation
-
Becker E., Huynh-Do U., Holland S., Pawson T., Daniel T.O., Skolnik E.Y. Nck-interacting Ste20 kinase couples Eph receptors to c-Jun N-terminal kinase and integrin activation. Mol Cell Biol 2000, 20(5):1537-1545.
-
(2000)
Mol Cell Biol
, vol.20
, Issue.5
, pp. 1537-1545
-
-
Becker, E.1
Huynh-Do, U.2
Holland, S.3
Pawson, T.4
Daniel, T.O.5
Skolnik, E.Y.6
-
64
-
-
33746646032
-
The EphB4 receptor suppresses breast cancer cell tumorigenicity through an Abl-Crk pathway
-
Noren N.K., Foos G., Hauser C.A., Pasquale E.B. The EphB4 receptor suppresses breast cancer cell tumorigenicity through an Abl-Crk pathway. Nat Cell Biol 2006, 8(8):815-825.
-
(2006)
Nat Cell Biol
, vol.8
, Issue.8
, pp. 815-825
-
-
Noren, N.K.1
Foos, G.2
Hauser, C.A.3
Pasquale, E.B.4
-
65
-
-
67650080520
-
Regulation of process retraction and cell migration by EphA3 is mediated by the adaptor protein Nck1
-
Hu T., Shi G., Larose L., Rivera G.M., Mayer B.J., Zhou R. Regulation of process retraction and cell migration by EphA3 is mediated by the adaptor protein Nck1. Biochemistry 2009, 48(27):6369-6378.
-
(2009)
Biochemistry
, vol.48
, Issue.27
, pp. 6369-6378
-
-
Hu, T.1
Shi, G.2
Larose, L.3
Rivera, G.M.4
Mayer, B.J.5
Zhou, R.6
-
66
-
-
84862834373
-
Eph-dependent cell-cell adhesion and segregation in development and cancer
-
[Epub ahead of print Dec 2011]
-
Nievergall E., Lackmann M., Janes P.W. Eph-dependent cell-cell adhesion and segregation in development and cancer. Cell Mol Life Sci 2011, [Epub ahead of print Dec 2011].
-
(2011)
Cell Mol Life Sci
-
-
Nievergall, E.1
Lackmann, M.2
Janes, P.W.3
-
67
-
-
77949412667
-
Restriction of receptor movement alters cellular response: physical force sensing by EphA2
-
Salaita K., Nair P.M., Petit R.S., Neve R.M., Das D., Gray J.W., et al. Restriction of receptor movement alters cellular response: physical force sensing by EphA2. Science 2010, 327(5971):1380-1385.
-
(2010)
Science
, vol.327
, Issue.5971
, pp. 1380-1385
-
-
Salaita, K.1
Nair, P.M.2
Petit, R.S.3
Neve, R.M.4
Das, D.5
Gray, J.W.6
-
69
-
-
76249132650
-
The EphB6 receptor cooperates with c-Cbl to regulate the behavior of breast cancer cells
-
Truitt L., Freywald T., DeCoteau J., Sharfe N., Freywald A. The EphB6 receptor cooperates with c-Cbl to regulate the behavior of breast cancer cells. Cancer Res 2010, 70(3):1141-1153.
-
(2010)
Cancer Res
, vol.70
, Issue.3
, pp. 1141-1153
-
-
Truitt, L.1
Freywald, T.2
DeCoteau, J.3
Sharfe, N.4
Freywald, A.5
-
70
-
-
77956849819
-
Ephrin-B1 forward signaling regulates craniofacial morphogenesis by controlling cell proliferation across Eph-ephrin boundaries
-
Bush J.O., Soriano P. Ephrin-B1 forward signaling regulates craniofacial morphogenesis by controlling cell proliferation across Eph-ephrin boundaries. Genes Dev 2010, 24(18):2068-2080.
-
(2010)
Genes Dev
, vol.24
, Issue.18
, pp. 2068-2080
-
-
Bush, J.O.1
Soriano, P.2
-
71
-
-
72149101924
-
Cell-specific information processing in segregating populations of Eph receptor ephrin-expressing cells
-
Jorgensen C., Sherman A., Chen G.I., Pasculescu A., Poliakov A., Hsiung M., et al. Cell-specific information processing in segregating populations of Eph receptor ephrin-expressing cells. Science 2009, 326(5959):1502-1509.
-
(2009)
Science
, vol.326
, Issue.5959
, pp. 1502-1509
-
-
Jorgensen, C.1
Sherman, A.2
Chen, G.I.3
Pasculescu, A.4
Poliakov, A.5
Hsiung, M.6
-
72
-
-
80155148301
-
The eph-receptor a7 is a soluble tumor suppressor for follicular lymphoma
-
Oricchio E., Nanjangud G., Wolfe A.L., Schatz J.H., Mavrakis K.J., Jiang M., et al. The eph-receptor a7 is a soluble tumor suppressor for follicular lymphoma. Cell 2011, 147(3):554-564.
-
(2011)
Cell
, vol.147
, Issue.3
, pp. 554-564
-
-
Oricchio, E.1
Nanjangud, G.2
Wolfe, A.L.3
Schatz, J.H.4
Mavrakis, K.J.5
Jiang, M.6
-
73
-
-
84855494260
-
Eph receptor function is modulated by heterooligomerization of A and B type Eph receptors
-
Janes P.W., Griesshaber B., Atapattu L., Nievergall E., Hii L.L., Mensinga A., et al. Eph receptor function is modulated by heterooligomerization of A and B type Eph receptors. J Cell Biol 2011, 195(6):1033-1045.
-
(2011)
J Cell Biol
, vol.195
, Issue.6
, pp. 1033-1045
-
-
Janes, P.W.1
Griesshaber, B.2
Atapattu, L.3
Nievergall, E.4
Hii, L.L.5
Mensinga, A.6
-
74
-
-
23044497596
-
Concurrent binding of anti-EphA3 antibody and ephrin-A5 amplifies EphA3 signaling and downstream responses: potential as EphA3-specific tumor-targeting reagents
-
Vearing C., Lee F.T., Wimmer-Kleikamp S., Spirkoska V., To C., Stylianou C., et al. Concurrent binding of anti-EphA3 antibody and ephrin-A5 amplifies EphA3 signaling and downstream responses: potential as EphA3-specific tumor-targeting reagents. Cancer Res 2005, 65(15):6745-6754.
-
(2005)
Cancer Res
, vol.65
, Issue.15
, pp. 6745-6754
-
-
Vearing, C.1
Lee, F.T.2
Wimmer-Kleikamp, S.3
Spirkoska, V.4
To, C.5
Stylianou, C.6
-
75
-
-
78649883292
-
Competition amongst Eph receptors regulates contact inhibition of locomotion and invasiveness in prostate cancer cells
-
Astin J.W., Batson J., Kadir S., Charlet J., Persad R.A., Gillatt D., et al. Competition amongst Eph receptors regulates contact inhibition of locomotion and invasiveness in prostate cancer cells. Nat Cell Biol 2010, 12(12):1194-1204.
-
(2010)
Nat Cell Biol
, vol.12
, Issue.12
, pp. 1194-1204
-
-
Astin, J.W.1
Batson, J.2
Kadir, S.3
Charlet, J.4
Persad, R.A.5
Gillatt, D.6
-
76
-
-
24744453982
-
Somatic mutations of the protein kinase gene family in human lung cancer
-
Davies H., Hunter C., Smith R., Stephens P., Greenman C., Bignell G., et al. Somatic mutations of the protein kinase gene family in human lung cancer. Cancer Res 2005, 65(17):7591-7595.
-
(2005)
Cancer Res
, vol.65
, Issue.17
, pp. 7591-7595
-
-
Davies, H.1
Hunter, C.2
Smith, R.3
Stephens, P.4
Greenman, C.5
Bignell, G.6
-
77
-
-
33749993417
-
The consensus coding sequences of human breast and colorectal cancers
-
Sjoblom T., Jones S., Wood L.D., Parsons D.W., Lin J., Barber T.D., et al. The consensus coding sequences of human breast and colorectal cancers. Science 2006, 314(5797):268-274.
-
(2006)
Science
, vol.314
, Issue.5797
, pp. 268-274
-
-
Sjoblom, T.1
Jones, S.2
Wood, L.D.3
Parsons, D.W.4
Lin, J.5
Barber, T.D.6
-
78
-
-
33749151698
-
Somatic mutations of GUCY2F: EPHA3, and NTRK3 in human cancers
-
Wood L.D., Calhoun E.S., Silliman N., Ptak J., Szabo S., Powell S.M., et al. Somatic mutations of GUCY2F: EPHA3, and NTRK3 in human cancers. Hum Mutat 2006, 27(10):1060-1061.
-
(2006)
Hum Mutat
, vol.27
, Issue.10
, pp. 1060-1061
-
-
Wood, L.D.1
Calhoun, E.S.2
Silliman, N.3
Ptak, J.4
Szabo, S.5
Powell, S.M.6
-
79
-
-
54549094903
-
Somatic mutations affect key pathways in lung adenocarcinoma
-
Ding L., Getz G., Wheeler D.A., Mardis E.R., McLellan M.D., Cibulskis K., et al. Somatic mutations affect key pathways in lung adenocarcinoma. Nature 2008, 455(7216):1069-1075.
-
(2008)
Nature
, vol.455
, Issue.7216
, pp. 1069-1075
-
-
Ding, L.1
Getz, G.2
Wheeler, D.A.3
Mardis, E.R.4
McLellan, M.D.5
Cibulskis, K.6
-
80
-
-
0034714357
-
Regulated cleavage of a contact-mediated axon repellent
-
Hattori M., Osterfield M., Flanagan J.G. Regulated cleavage of a contact-mediated axon repellent. Science 2000, 289(5483):1360-1365.
-
(2000)
Science
, vol.289
, Issue.5483
, pp. 1360-1365
-
-
Hattori, M.1
Osterfield, M.2
Flanagan, J.G.3
-
81
-
-
26844448800
-
Adam meets Eph: an ADAM substrate recognition module acts as a molecular switch for ephrin cleavage in trans
-
Janes P.W., Saha N., Barton W.A., Kolev M.V., Wimmer-Kleikamp S.H., Nievergall E., et al. Adam meets Eph: an ADAM substrate recognition module acts as a molecular switch for ephrin cleavage in trans. Cell 2005, 123(2):291-304.
-
(2005)
Cell
, vol.123
, Issue.2
, pp. 291-304
-
-
Janes, P.W.1
Saha, N.2
Barton, W.A.3
Kolev, M.V.4
Wimmer-Kleikamp, S.H.5
Nievergall, E.6
-
82
-
-
0035929146
-
Structural basis for autoinhibition of the Ephb2 receptor tyrosine kinase by the unphosphorylated juxtamembrane region
-
Wybenga-Groot L.E., Baskin B., Ong S.H., Tong J., Pawson T., Sicheri F. Structural basis for autoinhibition of the Ephb2 receptor tyrosine kinase by the unphosphorylated juxtamembrane region. Cell 2001, 106(6):745-757.
-
(2001)
Cell
, vol.106
, Issue.6
, pp. 745-757
-
-
Wybenga-Groot, L.E.1
Baskin, B.2
Ong, S.H.3
Tong, J.4
Pawson, T.5
Sicheri, F.6
-
83
-
-
70350503425
-
Cytoplasmic relaxation of active Eph controls ephrin shedding by ADAM10
-
Janes P.W., Wimmer-Kleikamp S.H., Frangakis A.S., Treble K., Griesshaber B., Sabet O., et al. Cytoplasmic relaxation of active Eph controls ephrin shedding by ADAM10. PLoS Biol 2009, 7(10):e1000215.
-
(2009)
PLoS Biol
, vol.7
, Issue.10
-
-
Janes, P.W.1
Wimmer-Kleikamp, S.H.2
Frangakis, A.S.3
Treble, K.4
Griesshaber, B.5
Sabet, O.6
-
84
-
-
54149090244
-
Meltrin beta/ADAM19 interacting with EphA4 in developing neural cells participates in formation of the neuromuscular junction
-
Yumoto N., Wakatsuki S., Kurisaki T., Hara Y., Osumi N., Frisén J., et al. Meltrin beta/ADAM19 interacting with EphA4 in developing neural cells participates in formation of the neuromuscular junction. PLoS One 2008, 3(10):e3322.
-
(2008)
PLoS One
, vol.3
, Issue.10
-
-
Yumoto, N.1
Wakatsuki, S.2
Kurisaki, T.3
Hara, Y.4
Osumi, N.5
Frisén, J.6
-
85
-
-
75149147806
-
Regulation of epidermal growth factor receptor trafficking by lysine deacetylase HDAC6
-
Deribe Y.L., Wild P., Chandrashaker A., Curak J., Schmidt M.H., Kalaidzidis Y., et al. Regulation of epidermal growth factor receptor trafficking by lysine deacetylase HDAC6. Sci Signal 2009, 2(102):ra84.
-
(2009)
Sci Signal
, vol.2
, Issue.102
-
-
Deribe, Y.L.1
Wild, P.2
Chandrashaker, A.3
Curak, J.4
Schmidt, M.H.5
Kalaidzidis, Y.6
-
86
-
-
17844406391
-
Phosphotyrosine signaling networks in epidermal growth factor receptor overexpressing squamous carcinoma cells
-
Thelemann A., Petti F., Griffin G., Iwata K., Hunt T., Settinari T., et al. Phosphotyrosine signaling networks in epidermal growth factor receptor overexpressing squamous carcinoma cells. Mol Cell Proteomics 2005, 4(4):356-376.
-
(2005)
Mol Cell Proteomics
, vol.4
, Issue.4
, pp. 356-376
-
-
Thelemann, A.1
Petti, F.2
Griffin, G.3
Iwata, K.4
Hunt, T.5
Settinari, T.6
-
87
-
-
77954222255
-
Comprehensive mapping of the human kinome to epidermal growth factor receptor signaling
-
Komurov K., Padron D., Cheng T., Roth M., Rosenblatt K.P., White M.A. Comprehensive mapping of the human kinome to epidermal growth factor receptor signaling. J Biol Chem 2010, 285(27):21134-21142.
-
(2010)
J Biol Chem
, vol.285
, Issue.27
, pp. 21134-21142
-
-
Komurov, K.1
Padron, D.2
Cheng, T.3
Roth, M.4
Rosenblatt, K.P.5
White, M.A.6
-
88
-
-
34147120088
-
Activation of the EGFR gene target EphA2 inhibits epidermal growth factor-induced cancer cell motility
-
Larsen A.B., Pedersen M.W., Stockhausen M.T., Grandal M.V., van Deurs B., Poulsen H.S. Activation of the EGFR gene target EphA2 inhibits epidermal growth factor-induced cancer cell motility. Mol Cancer Res 2007, 5(3):283-293.
-
(2007)
Mol Cancer Res
, vol.5
, Issue.3
, pp. 283-293
-
-
Larsen, A.B.1
Pedersen, M.W.2
Stockhausen, M.T.3
Grandal, M.V.4
van Deurs, B.5
Poulsen, H.S.6
-
89
-
-
74449091169
-
Cell adhesion and EGFR activation regulate EphA2 expression in cancer
-
Larsen A.B., Stockhausen M.T., Poulsen H.S. Cell adhesion and EGFR activation regulate EphA2 expression in cancer. Cell Signal 2010, 22(4):636-644.
-
(2010)
Cell Signal
, vol.22
, Issue.4
, pp. 636-644
-
-
Larsen, A.B.1
Stockhausen, M.T.2
Poulsen, H.S.3
-
90
-
-
38149137411
-
The receptor tyrosine kinase EphA2 promotes mammary adenocarcinoma tumorigenesis and metastatic progression in mice by amplifying ErbB2 signaling
-
Brantley-Sieders D.M., Zhuang G., Hicks D., Fang W.B., Hwang Y., Cates J.M., et al. The receptor tyrosine kinase EphA2 promotes mammary adenocarcinoma tumorigenesis and metastatic progression in mice by amplifying ErbB2 signaling. J Clin Invest 2008, 118(1):64-78.
-
(2008)
J Clin Invest
, vol.118
, Issue.1
, pp. 64-78
-
-
Brantley-Sieders, D.M.1
Zhuang, G.2
Hicks, D.3
Fang, W.B.4
Hwang, Y.5
Cates, J.M.6
-
91
-
-
54049153684
-
EphA4 promotes cell proliferation and migration through a novel EphA4-FGFR1 signaling pathway in the human glioma U251 cell line
-
Fukai J., Yokote H., Yamanaka R., Arao T., Nishio K., Itakura T. EphA4 promotes cell proliferation and migration through a novel EphA4-FGFR1 signaling pathway in the human glioma U251 cell line. Mol Cancer Ther 2008, 7(9):2768-2778.
-
(2008)
Mol Cancer Ther
, vol.7
, Issue.9
, pp. 2768-2778
-
-
Fukai, J.1
Yokote, H.2
Yamanaka, R.3
Arao, T.4
Nishio, K.5
Itakura, T.6
-
92
-
-
1642423563
-
Ectopic EphA4 receptor induces posterior protrusions via FGF signaling in Xenopus embryos
-
Park E.K., Warner N., Bong Y.S., Stapleton D., Maeda R., Pawson T., et al. Ectopic EphA4 receptor induces posterior protrusions via FGF signaling in Xenopus embryos. Mol Biol Cell 2004, 15(4):1647-1655.
-
(2004)
Mol Biol Cell
, vol.15
, Issue.4
, pp. 1647-1655
-
-
Park, E.K.1
Warner, N.2
Bong, Y.S.3
Stapleton, D.4
Maeda, R.5
Pawson, T.6
-
93
-
-
30044439558
-
Trans-activation of EphA4 and FGF receptors mediated by direct interactions between their cytoplasmic domains
-
Yokote H., Fujita K., Jing X., Sawada T., Liang S., Yao L., et al. Trans-activation of EphA4 and FGF receptors mediated by direct interactions between their cytoplasmic domains. Proc Natl Acad Sci USA 2005, 102(52):18866-18871.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, Issue.52
, pp. 18866-18871
-
-
Yokote, H.1
Fujita, K.2
Jing, X.3
Sawada, T.4
Liang, S.5
Yao, L.6
-
94
-
-
58149288204
-
Regulation of EphB2 activation and cell repulsion by feedback control of the MAPK pathway
-
Poliakov A., Cotrina M.L., Pasini A., Wilkinson D.G. Regulation of EphB2 activation and cell repulsion by feedback control of the MAPK pathway. J Cell Biol 2008, 183(5):933-947.
-
(2008)
J Cell Biol
, vol.183
, Issue.5
, pp. 933-947
-
-
Poliakov, A.1
Cotrina, M.L.2
Pasini, A.3
Wilkinson, D.G.4
-
95
-
-
84857444503
-
EphB ligand, ephrinB2, suppresses the VEGF- and angiopoietin-1-induced Ras/mitogen-activated protein kinase pathway in venous endothelial cells
-
Kim I., Ryu Y.S., Kwak H.J., Ahn S.Y., Oh J.-L., Yancopoulos G.D., et al. EphB ligand, ephrinB2, suppresses the VEGF- and angiopoietin-1-induced Ras/mitogen-activated protein kinase pathway in venous endothelial cells. FASEB J 2002, 1-805.
-
(2002)
FASEB J
, pp. 1-805
-
-
Kim, I.1
Ryu, Y.S.2
Kwak, H.J.3
Ahn, S.Y.4
Oh, J.-L.5
Yancopoulos, G.D.6
-
96
-
-
30344452563
-
EphrinA1 inhibits vascular endothelial growth factor-induced intracellular signaling and suppresses retinal neovascularization and blood-retinal barrier breakdown
-
Ojima T., Takagi H., Suzuma K., Oh H., Suzuma I., Ohashi H., et al. EphrinA1 inhibits vascular endothelial growth factor-induced intracellular signaling and suppresses retinal neovascularization and blood-retinal barrier breakdown. Am J Pathol 2006, 168(1):331-339.
-
(2006)
Am J Pathol
, vol.168
, Issue.1
, pp. 331-339
-
-
Ojima, T.1
Takagi, H.2
Suzuma, K.3
Oh, H.4
Suzuma, I.5
Ohashi, H.6
-
97
-
-
0034426014
-
Ryk-deficient mice exhibit craniofacial defects associated with perturbed Eph receptor crosstalk
-
Halford M.M., Armes J., Buchert M., Meskenaite V., Grail D., Hibbs M.L., et al. Ryk-deficient mice exhibit craniofacial defects associated with perturbed Eph receptor crosstalk. Nat Genet 2000, 25(4):414-418.
-
(2000)
Nat Genet
, vol.25
, Issue.4
, pp. 414-418
-
-
Halford, M.M.1
Armes, J.2
Buchert, M.3
Meskenaite, V.4
Grail, D.5
Hibbs, M.L.6
-
99
-
-
15744377388
-
Receptor related to tyrosine kinase RYK regulates cell migration during cortical development
-
Kamitori K., Tanaka M., Okuno-Hirasawa T., Kohsaka S. Receptor related to tyrosine kinase RYK regulates cell migration during cortical development. Biochem Biophys Res Commun 2005, 330(2):446-453.
-
(2005)
Biochem Biophys Res Commun
, vol.330
, Issue.2
, pp. 446-453
-
-
Kamitori, K.1
Tanaka, M.2
Okuno-Hirasawa, T.3
Kohsaka, S.4
-
100
-
-
0037151113
-
RYK, a catalytically inactive receptor tyrosine kinase: associates with EphB2 and EphB3 but does not interact with AF-6
-
Trivier E., Ganesan T.S. RYK, a catalytically inactive receptor tyrosine kinase: associates with EphB2 and EphB3 but does not interact with AF-6. J Biol Chem 2002, 277(25):23037-23043.
-
(2002)
J Biol Chem
, vol.277
, Issue.25
, pp. 23037-23043
-
-
Trivier, E.1
Ganesan, T.S.2
-
101
-
-
33751168256
-
EphB2 and EphB4 receptors forward signaling promotes SDF-1-induced endothelial cell chemotaxis and branching remodeling
-
Salvucci O., de la Luz S.M., Martina J.A., McCormick P.J., Tosato G. EphB2 and EphB4 receptors forward signaling promotes SDF-1-induced endothelial cell chemotaxis and branching remodeling. Blood 2006, 108(9):2914-2922.
-
(2006)
Blood
, vol.108
, Issue.9
, pp. 2914-2922
-
-
Salvucci, O.1
de la Luz, S.M.2
Martina, J.A.3
McCormick, P.J.4
Tosato, G.5
-
102
-
-
0036918644
-
Ephrin stimulation modulates T cell chemotaxis
-
Sharfe N., Freywald A., Toro A., Dadi H., Roifman C. Ephrin stimulation modulates T cell chemotaxis. Eur J Immunol 2002, 32(12):3745-3755.
-
(2002)
Eur J Immunol
, vol.32
, Issue.12
, pp. 3745-3755
-
-
Sharfe, N.1
Freywald, A.2
Toro, A.3
Dadi, H.4
Roifman, C.5
-
103
-
-
0035924602
-
The receptor tyrosine kinase EphB2 regulates NMDA-dependent synaptic function
-
Henderson J.T., Georgiou J., Jia Z., Robertson J., Elowe S., Roder J.C., et al. The receptor tyrosine kinase EphB2 regulates NMDA-dependent synaptic function. Neuron 2001, 32(6):1041-1056.
-
(2001)
Neuron
, vol.32
, Issue.6
, pp. 1041-1056
-
-
Henderson, J.T.1
Georgiou, J.2
Jia, Z.3
Robertson, J.4
Elowe, S.5
Roder, J.C.6
-
104
-
-
0033635736
-
EphB receptors interact with NMDA receptors and regulate excitatory synapse formation
-
Dalva M.B., Takasu M.A., Lin M.Z., Shamah S.M., Hu L., Gale N.W., et al. EphB receptors interact with NMDA receptors and regulate excitatory synapse formation. Cell 2000, 103(6):945-956.
-
(2000)
Cell
, vol.103
, Issue.6
, pp. 945-956
-
-
Dalva, M.B.1
Takasu, M.A.2
Lin, M.Z.3
Shamah, S.M.4
Hu, L.5
Gale, N.W.6
-
105
-
-
0037127073
-
Modulation of NMDA receptor-dependent calcium influx and gene expression through EphB receptors
-
Takasu M.A., Dalva M.B., Zigmond R.E., Greenberg M.E. Modulation of NMDA receptor-dependent calcium influx and gene expression through EphB receptors. Science 2002, 295(5554):491-495.
-
(2002)
Science
, vol.295
, Issue.5554
, pp. 491-495
-
-
Takasu, M.A.1
Dalva, M.B.2
Zigmond, R.E.3
Greenberg, M.E.4
-
106
-
-
0037047122
-
Interactions between Eph kinases and ephrins provide a mechanism to support platelet aggregation once cell-to-cell contact has occurred
-
Prevost N., Woulfe D., Tanaka T., Brass L.F. Interactions between Eph kinases and ephrins provide a mechanism to support platelet aggregation once cell-to-cell contact has occurred. Proc Natl Acad Sci USA 2002, 99(14):9219-9224.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, Issue.14
, pp. 9219-9224
-
-
Prevost, N.1
Woulfe, D.2
Tanaka, T.3
Brass, L.F.4
-
107
-
-
77957237289
-
EphB signaling directs peripheral nerve regeneration through Sox2-dependent Schwann cell sorting
-
Parrinello S., Napoli I., Ribeiro S., Digby P.W., Fedorova M., Parkinson D.B., et al. EphB signaling directs peripheral nerve regeneration through Sox2-dependent Schwann cell sorting. Cell 2010, 143(1):145-155.
-
(2010)
Cell
, vol.143
, Issue.1
, pp. 145-155
-
-
Parrinello, S.1
Napoli, I.2
Ribeiro, S.3
Digby, P.W.4
Fedorova, M.5
Parkinson, D.B.6
-
108
-
-
33644645280
-
VE-cadherin regulates EphA2 in aggressive melanoma cells through a novel signaling pathway: implications for vasculogenic mimicry
-
Hess A.R., Seftor E.A., Gruman L.M., Kinch M.S., Seftor R.E., Hendrix M.J. VE-cadherin regulates EphA2 in aggressive melanoma cells through a novel signaling pathway: implications for vasculogenic mimicry. Cancer Biol Ther 2006, 5(2):228-233.
-
(2006)
Cancer Biol Ther
, vol.5
, Issue.2
, pp. 228-233
-
-
Hess, A.R.1
Seftor, E.A.2
Gruman, L.M.3
Kinch, M.S.4
Seftor, R.E.5
Hendrix, M.J.6
-
109
-
-
0034072748
-
Expression of Eph receptors and ephrins is differentially regulated by E-cadherin
-
Orsulic S., Kemler R. Expression of Eph receptors and ephrins is differentially regulated by E-cadherin. J Cell Sci 2000, 113(Pt 10):1793-1802.
-
(2000)
J Cell Sci
, vol.113
, Issue.PART 10
, pp. 1793-1802
-
-
Orsulic, S.1
Kemler, R.2
-
110
-
-
0032834125
-
E-cadherin regulates the function of the EphA2 receptor tyrosine kinase
-
Zantek N.D., Azimi M., Fedor-Chaiken M., Wang B., Brackenbury R., Kinch M.S. E-cadherin regulates the function of the EphA2 receptor tyrosine kinase. Cell Growth Differ 1999, 10(9):629-638.
-
(1999)
Cell Growth Differ
, vol.10
, Issue.9
, pp. 629-638
-
-
Zantek, N.D.1
Azimi, M.2
Fedor-Chaiken, M.3
Wang, B.4
Brackenbury, R.5
Kinch, M.S.6
-
111
-
-
35548976379
-
EphB-ephrin-B interactions suppress colorectal cancer progression by compartmentalizing tumor cells
-
Cortina C., Palomo-Ponce S., Iglesias M., Fernandez-Masip J.L., Vivancos A., Whissell G., et al. EphB-ephrin-B interactions suppress colorectal cancer progression by compartmentalizing tumor cells. Nat Genet 2007, 39(11):1376-1383.
-
(2007)
Nat Genet
, vol.39
, Issue.11
, pp. 1376-1383
-
-
Cortina, C.1
Palomo-Ponce, S.2
Iglesias, M.3
Fernandez-Masip, J.L.4
Vivancos, A.5
Whissell, G.6
-
112
-
-
80052499952
-
Cleavage of E-cadherin by ADAM10 mediates epithelial cell sorting downstream of EphB signalling
-
Solanas G., Cortina C., Sevillano M., Batlle E. Cleavage of E-cadherin by ADAM10 mediates epithelial cell sorting downstream of EphB signalling. Nat Cell Biol 2011, 13(9):1100-1107.
-
(2011)
Nat Cell Biol
, vol.13
, Issue.9
, pp. 1100-1107
-
-
Solanas, G.1
Cortina, C.2
Sevillano, M.3
Batlle, E.4
-
113
-
-
0141839882
-
Rac-dependent trans-endocytosis of ephrinBs regulates Eph-ephrin contact repulsion
-
Marston D.J., Dickinson S., Nobes C.D. Rac-dependent trans-endocytosis of ephrinBs regulates Eph-ephrin contact repulsion. Nat Cell Biol 2003, 5(10):879-888.
-
(2003)
Nat Cell Biol
, vol.5
, Issue.10
, pp. 879-888
-
-
Marston, D.J.1
Dickinson, S.2
Nobes, C.D.3
-
114
-
-
0141839883
-
EphB-ephrinB bi-directional endocytosis terminates adhesion allowing contact mediated repulsion
-
Zimmer M., Palmer A., Kohler J., Klein R. EphB-ephrinB bi-directional endocytosis terminates adhesion allowing contact mediated repulsion. Nat Cell Biol 2003, 5(10):869-878.
-
(2003)
Nat Cell Biol
, vol.5
, Issue.10
, pp. 869-878
-
-
Zimmer, M.1
Palmer, A.2
Kohler, J.3
Klein, R.4
-
115
-
-
75749096347
-
The endocytic matrix
-
Scita G., Di Fiore P.P. The endocytic matrix. Nature 2010, 463(7280):464-473.
-
(2010)
Nature
, vol.463
, Issue.7280
, pp. 464-473
-
-
Scita, G.1
Di Fiore, P.P.2
-
116
-
-
50949083485
-
Elevated protein tyrosine phosphatase activity provokes Eph/ephrin-facilitated adhesion of pre-B leukemia cells
-
Wimmer-Kleikamp S.H., Nievergall E., Gegenbauer K., Adikari S., Mansour M., Yeadon T., et al. Elevated protein tyrosine phosphatase activity provokes Eph/ephrin-facilitated adhesion of pre-B leukemia cells. Blood 2008, 112(3):721-732.
-
(2008)
Blood
, vol.112
, Issue.3
, pp. 721-732
-
-
Wimmer-Kleikamp, S.H.1
Nievergall, E.2
Gegenbauer, K.3
Adikari, S.4
Mansour, M.5
Yeadon, T.6
-
117
-
-
33745698914
-
Eph receptors are negatively controlled by protein tyrosine phosphatase receptor type O
-
Shintani T., Ihara M., Sakuta H., Takahashi H., Watakabe I., Noda M. Eph receptors are negatively controlled by protein tyrosine phosphatase receptor type O. Nat Neurosci 2006, 9(6):761-769.
-
(2006)
Nat Neurosci
, vol.9
, Issue.6
, pp. 761-769
-
-
Shintani, T.1
Ihara, M.2
Sakuta, H.3
Takahashi, H.4
Watakabe, I.5
Noda, M.6
-
118
-
-
78650141935
-
PTP1B regulates Eph receptor function and trafficking
-
Nievergall E., Janes P.W., Stegmayer C., Vail M.E., Haj F.G., Teng S.W., et al. PTP1B regulates Eph receptor function and trafficking. J Cell Biol 2010, 191(6):1189-1203.
-
(2010)
J Cell Biol
, vol.191
, Issue.6
, pp. 1189-1203
-
-
Nievergall, E.1
Janes, P.W.2
Stegmayer, C.3
Vail, M.E.4
Haj, F.G.5
Teng, S.W.6
-
119
-
-
21344460054
-
EphB receptor activity suppresses colorectal cancer progression
-
Batlle E., Bacani J., Begthel H., Jonkheer S., Gregorieff A., van de Born M., et al. EphB receptor activity suppresses colorectal cancer progression. Nature 2005, 435(7045):1126-1130.
-
(2005)
Nature
, vol.435
, Issue.7045
, pp. 1126-1130
-
-
Batlle, E.1
Bacani, J.2
Begthel, H.3
Jonkheer, S.4
Gregorieff, A.5
van de Born, M.6
-
120
-
-
34249329249
-
Paradoxes of the EphB4 receptor in cancer
-
Noren N.K., Pasquale E.B. Paradoxes of the EphB4 receptor in cancer. Cancer Res 2007, 67(9):3994-3997.
-
(2007)
Cancer Res
, vol.67
, Issue.9
, pp. 3994-3997
-
-
Noren, N.K.1
Pasquale, E.B.2
-
121
-
-
41549139097
-
Eph-ephrin signalling in adult tissues and cancer
-
Merlos-Suarez A., Battle E. Eph-ephrin signalling in adult tissues and cancer. Curr Opin Cell Biol 2008, 20:194-200.
-
(2008)
Curr Opin Cell Biol
, vol.20
, pp. 194-200
-
-
Merlos-Suarez, A.1
Battle, E.2
-
122
-
-
34248547564
-
Novel somatic and germline mutations in cancer candidate genes in glioblastoma: melanoma, and pancreatic carcinoma
-
Balakrishnan A., Bleeker F.E., Lamba S., Rodolfo M., Daniotti M., Scarpa A., et al. Novel somatic and germline mutations in cancer candidate genes in glioblastoma: melanoma, and pancreatic carcinoma. Cancer Res 2007, 67(8):3545-3550.
-
(2007)
Cancer Res
, vol.67
, Issue.8
, pp. 3545-3550
-
-
Balakrishnan, A.1
Bleeker, F.E.2
Lamba, S.3
Rodolfo, M.4
Daniotti, M.5
Scarpa, A.6
-
123
-
-
77958603990
-
Mutational profiling of kinases in human tumours of pancreatic origin identifies candidate cancer genes in ductal and ampulla of vater carcinomas
-
Corbo V., Ritelli R., Barbi S., Funel N., Campani D., Bardelli A., et al. Mutational profiling of kinases in human tumours of pancreatic origin identifies candidate cancer genes in ductal and ampulla of vater carcinomas. PLoS One 2010, 5(9):e12653.
-
(2010)
PLoS One
, vol.5
, Issue.9
-
-
Corbo, V.1
Ritelli, R.2
Barbi, S.3
Funel, N.4
Campani, D.5
Bardelli, A.6
-
124
-
-
77955660663
-
Diverse somatic mutation patterns and pathway alterations in human cancers
-
Kan Z., Jaiswal B.S., Stinson J., Janakiraman V., Bhatt D., Stern H.M., et al. Diverse somatic mutation patterns and pathway alterations in human cancers. Nature 2010, 466(7308):869-873.
-
(2010)
Nature
, vol.466
, Issue.7308
, pp. 869-873
-
-
Kan, Z.1
Jaiswal, B.S.2
Stinson, J.3
Janakiraman, V.4
Bhatt, D.5
Stern, H.M.6
-
125
-
-
51449099398
-
Germline EPHB2 receptor variants in familial colorectal cancer
-
Zogopoulos G., Jorgensen C., Bacani J., Montpetit A., Lepage P., Ferretti V., et al. Germline EPHB2 receptor variants in familial colorectal cancer. PLoS One 2008, 3(8):e2885.
-
(2008)
PLoS One
, vol.3
, Issue.8
-
-
Zogopoulos, G.1
Jorgensen, C.2
Bacani, J.3
Montpetit, A.4
Lepage, P.5
Ferretti, V.6
-
126
-
-
4444326581
-
Nonsense-mediated decay microarray analysis identifies mutations of EPHB2 in human prostate cancer
-
Huusko P., Ponciano-Jackson D., Wolf M., Kiefer J.A., Azorsa D.O., Tuzmen S., et al. Nonsense-mediated decay microarray analysis identifies mutations of EPHB2 in human prostate cancer. Nat Genet 2004, 36(9):979-983.
-
(2004)
Nat Genet
, vol.36
, Issue.9
, pp. 979-983
-
-
Huusko, P.1
Ponciano-Jackson, D.2
Wolf, M.3
Kiefer, J.A.4
Azorsa, D.O.5
Tuzmen, S.6
-
127
-
-
37049003993
-
Genetic alterations in the tyrosine kinase transcriptome of human cancer cell lines
-
Ruhe J.E., Streit S., Hart S., Wong C.H., Specht K., Knyazev P., et al. Genetic alterations in the tyrosine kinase transcriptome of human cancer cell lines. Cancer Res 2007, 67(23):11368-11376.
-
(2007)
Cancer Res
, vol.67
, Issue.23
, pp. 11368-11376
-
-
Ruhe, J.E.1
Streit, S.2
Hart, S.3
Wong, C.H.4
Specht, K.5
Knyazev, P.6
-
128
-
-
68149142724
-
Low frequency mutation of the Ephrin receptor A3 gene in hepatocellular carcinoma
-
Bae H.J., Song J.H., Noh J.H., Kim J.K., Jung K.H., Eun J.W., et al. Low frequency mutation of the Ephrin receptor A3 gene in hepatocellular carcinoma. Neoplasma 2009, 56(4):331-334.
-
(2009)
Neoplasma
, vol.56
, Issue.4
, pp. 331-334
-
-
Bae, H.J.1
Song, J.H.2
Noh, J.H.3
Kim, J.K.4
Jung, K.H.5
Eun, J.W.6
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