메뉴 건너뛰기




Volumn 27, Issue 5, 2013, Pages 491-503

The Smurf ubiquitin ligases regulate tissue separation via antagonistic interactions with ephrinB1

Author keywords

Cell adhesion; EphrinB1; Smurf; Tissue boundaries

Indexed keywords

EPHRIN B1; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; SMAD UBIQUITIN REGULATORY FACTOR 1; SMAD UBIQUITIN REGULATORY FACTOR 2; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

EID: 84874895637     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.208355.112     Document Type: Article
Times cited : (21)

References (56)
  • 1
    • 33750286555 scopus 로고    scopus 로고
    • Smurf1 regulates neural patterning and folding in Xenopus embryos by antagonizing the BMP/Smad1 pathway
    • Alexandrova EM, Thomsen GH. (2006). Smurf1 regulates neural patterning and folding in Xenopus embryos by antagonizing the BMP/Smad1 pathway. Dev Biol 299: 398-410.
    • (2006) Dev Biol , vol.299 , pp. 398-410
    • Alexandrova, E.M.1    Thomsen, G.H.2
  • 3
    • 77949558617 scopus 로고    scopus 로고
    • Nominal-ordinal measures of association: A comparison of two measures
    • Berry KJ, Johnston JE, Mielke PW Jr. (2009). Nominal-ordinal measures of association: A comparison of two measures. Percept Mot Skills 109: 285-294.
    • (2009) Percept Mot Skills , vol.109 , pp. 285-294
    • Berry, K.J.1    Johnston, J.E.2    Mielke Jr., P.W.3
  • 4
  • 5
    • 84857443558 scopus 로고    scopus 로고
    • Eph/ephrin signaling: Genetic, phosphoproteomic, and transcriptomic approaches
    • Bush JO, Soriano P. (2012). Eph/ephrin signaling: Genetic, phosphoproteomic, and transcriptomic approaches. Semin Cell Dev Biol 23: 26-34.
    • (2012) Semin Cell Dev Biol , vol.23 , pp. 26-34
    • Bush, J.O.1    Soriano, P.2
  • 6
    • 84879072668 scopus 로고    scopus 로고
    • A Smurf1 tale: Function and regulation of an ubiquitin ligase in multiple cellular networks
    • doi: 10.1007/s00018-012-1170-7
    • Cao Y, Zhang L. (2012). A Smurf1 tale: Function and regulation of an ubiquitin ligase in multiple cellular networks. Cell Mol Life Sci doi: 10.1007/s00018-012-1170-7.
    • (2012) Cell Mol Life Sci
    • Cao, Y.1    Zhang, L.2
  • 7
    • 78751697205 scopus 로고    scopus 로고
    • Phosphorylation of E3 ligase Smurf1 switches its substrate preference in support of axon development
    • Cheng PL, Lu H, Shelly M, Gao H, Poo MM. (2011). Phosphorylation of E3 ligase Smurf1 switches its substrate preference in support of axon development. Neuron 69: 231-243.
    • (2011) Neuron , vol.69 , pp. 231-243
    • Cheng, P.L.1    Lu, H.2    Shelly, M.3    Gao, H.4    Poo, M.M.5
  • 8
    • 0033961810 scopus 로고    scopus 로고
    • Fibroblast growth factor receptor-mediated rescue of x-ephrin B1-induced cell dissociation in Xenopus embryos
    • Chong LD, Park EK, Latimer E, Friesel R, Daar IO. (2000). Fibroblast growth factor receptor-mediated rescue of x-ephrin B1-induced cell dissociation in Xenopus embryos. Mol Cell Biol 20: 724-734.
    • (2000) Mol Cell Biol , vol.20 , pp. 724-734
    • Chong, L.D.1    Park, E.K.2    Latimer, E.3    Friesel, R.4    Daar, I.O.5
  • 9
    • 78649875435 scopus 로고    scopus 로고
    • Coupling of tandem Smad ubiquitination regulatory factor (Smurf) WW domains modulates target specificity
    • Chong PA, Lin H, Wrana JL, Forman-Kay JD. (2010). Coupling of tandem Smad ubiquitination regulatory factor (Smurf) WW domains modulates target specificity. Proc Natl Acad Sci 107: 18404-18409.
    • (2010) Proc Natl Acad Sci , vol.107 , pp. 18404-18409
    • Chong, P.A.1    Lin, H.2    Wrana, J.L.3    Forman-Kay, J.D.4
  • 10
    • 84857442761 scopus 로고    scopus 로고
    • Non-SH2/PDZ reverse signaling by ephrins
    • Daar IO. (2012). Non-SH2/PDZ reverse signaling by ephrins. Semin Cell Dev Biol 23: 65-74.
    • (2012) Semin Cell Dev Biol , vol.23 , pp. 65-74
    • Daar, I.O.1
  • 11
    • 84863999039 scopus 로고    scopus 로고
    • Regulation of early Xenopus embryogenesis by Smad ubiquitination regulatory factor 2
    • Das S, Chang C. (2012). Regulation of early Xenopus embryogenesis by Smad ubiquitination regulatory factor 2. Dev Dyn 241: 1260-1273.
    • (2012) Dev Dyn , vol.241 , pp. 1260-1273
    • Das, S.1    Chang, C.2
  • 12
    • 0035918274 scopus 로고    scopus 로고
    • Smurf1 interacts with transforming growth factor-b type I receptor through Smad7 and induces receptor degradation
    • Ebisawa T, Fukuchi M, Murakami G, Chiba T, Tanaka K, Imamura T, Miyazono K. (2001). Smurf1 interacts with transforming growth factor-b type I receptor through Smad7 and induces receptor degradation. J Biol Chem276: 12477-12480.
    • (2001) J Biol Chem , vol.276 , pp. 12477-12480
    • Ebisawa, T.1    Fukuchi, M.2    Murakami, G.3    Chiba, T.4    Tanaka, K.5    Imamura, T.6    Miyazono, K.7
  • 14
    • 84874912811 scopus 로고    scopus 로고
    • Brachet's cleft: A model for the analysis of tissue separation in Xenopus
    • Gorny A-K, Steinbeisser H. (2012). Brachet's cleft: A model for the analysis of tissue separation in Xenopus. Wiley Interdiscip Rev Dev Biol 1: 294-300.
    • (2012) Wiley Interdiscip Rev Dev Biol , vol.1 , pp. 294-300
    • Gorny, A.-K.1    Steinbeisser, H.2
  • 16
    • 77449137856 scopus 로고    scopus 로고
    • Roles of E3 ubiquitin ligases in cell adhesion and migration
    • Huang C. (2010). Roles of E3 ubiquitin ligases in cell adhesion and migration. Cell Adhes Migr 4: 10-18.
    • (2010) Cell Adhes Migr , vol.4 , pp. 10-18
    • Huang, C.1
  • 17
    • 65449148205 scopus 로고    scopus 로고
    • Talin phosphorylation by Cdk5 regulates Smurf1-mediated talin head ubiquitylation and cell migration
    • Huang C, Rajfur Z, Yousefi N, Chen Z, Jacobson K, Ginsberg MH. (2009). Talin phosphorylation by Cdk5 regulates Smurf1-mediated talin head ubiquitylation and cell migration. Nat Cell Biol 11: 624-630.
    • (2009) Nat Cell Biol , vol.11 , pp. 624-630
    • Huang, C.1    Rajfur, Z.2    Yousefi, N.3    Chen, Z.4    Jacobson, K.5    Ginsberg, M.H.6
  • 18
    • 1942534004 scopus 로고    scopus 로고
    • Regulation of the TGFb signalling pathway by ubiquitin-mediated degradation
    • Izzi L, Attisano L. (2004). Regulation of the TGFb signalling pathway by ubiquitin-mediated degradation. Oncogene 23: 2071-2078.
    • (2004) Oncogene , vol.23 , pp. 2071-2078
    • Izzi, L.1    Attisano, L.2
  • 19
    • 59149091922 scopus 로고    scopus 로고
    • Smad ubiquitination regulatory factor 2 promotes metastasis of breast cancer cells by enhancing migration and invasiveness
    • Jin C, Yang YA, Anver MR, Morris N, Wang X, Zhang YE. (2009). Smad ubiquitination regulatory factor 2 promotes metastasis of breast cancer cells by enhancing migration and invasiveness. Cancer Res 69: 735-740.
    • (2009) Cancer Res , vol.69 , pp. 735-740
    • Jin, C.1    Yang, Y.A.2    Anver, M.R.3    Morris, N.4    Wang, X.5    Zhang, Y.E.6
  • 20
    • 84865838325 scopus 로고    scopus 로고
    • The E3 ligase Cdh1-anaphase promoting complex operates upstream of the E3 ligase Smurf1 in the control of axon growth
    • Kannan M, Lee SJ, Schwedhelm-Domeyer N, Stegmuller J. (2012). The E3 ligase Cdh1-anaphase promoting complex operates upstream of the E3 ligase Smurf1 in the control of axon growth. Development 139: 3600-3612.
    • (2012) Development , vol.139 , pp. 3600-3612
    • Kannan, M.1    Lee, S.J.2    Schwedhelm-Domeyer, N.3    Stegmuller, J.4
  • 21
    • 0034517389 scopus 로고    scopus 로고
    • Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF b receptor for degradation
    • Kavsak P, Rasmussen RK, Causing CG, Bonni S, Zhu H, Thomsen GH, Wrana JL. (2000). Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF b receptor for degradation. Mol Cell 6: 1365-1375.
    • (2000) Mol Cell , vol.6 , pp. 1365-1375
    • Kavsak, P.1    Rasmussen, R.K.2    Causing, C.G.3    Bonni, S.4    Zhu, H.5    Thomsen, G.H.6    Wrana, J.L.7
  • 22
    • 38349050937 scopus 로고    scopus 로고
    • Developmental regulation of central spindle assembly and cytokinesis during vertebrate embryogenesis
    • Kieserman EK, Glotzer M, Wallingford JB. (2008). Developmental regulation of central spindle assembly and cytokinesis during vertebrate embryogenesis. Curr Biol 18: 116-123.
    • (2008) Curr Biol , vol.18 , pp. 116-123
    • Kieserman, E.K.1    Glotzer, M.2    Wallingford, J.B.3
  • 23
    • 77955057680 scopus 로고    scopus 로고
    • xGit2 and xRhoGAP 11A regulate convergent extension and tissue separation in Xenopus gastrulation
    • Koster I, JungwirthMS, Steinbeisser H. (2010). xGit2 and xRhoGAP 11A regulate convergent extension and tissue separation in Xenopus gastrulation. Dev Biol 344: 26-35.
    • (2010) Dev Biol , vol.344 , pp. 26-35
    • Koster, I.1    Jungwirth, M.S.2    Steinbeisser, H.3
  • 24
    • 30344474298 scopus 로고    scopus 로고
    • Dishevelled mediates ephrinB1 signalling in the eye field through the planar cell polarity pathway
    • Lee HS, Bong YS, Moore KB, Soria K, Moody SA, Daar IO. (2006). Dishevelled mediates ephrinB1 signalling in the eye field through the planar cell polarity pathway. Nat Cell Biol 8: 55-63.
    • (2006) Nat Cell Biol , vol.8 , pp. 55-63
    • Lee, H.S.1    Bong, Y.S.2    Moore, K.B.3    Soria, K.4    Moody, S.A.5    Daar, I.O.6
  • 25
    • 48649107982 scopus 로고    scopus 로고
    • EphrinB1 controls cell-cell junctions through the Par polarity complex
    • Lee HS, Nishanian TG, Mood K, Bong YS, Daar IO. (2008). EphrinB1 controls cell-cell junctions through the Par polarity complex. Nat Cell Biol 10: 979-986.
    • (2008) Nat Cell Biol , vol.10 , pp. 979-986
    • Lee, H.S.1    Nishanian, T.G.2    Mood, K.3    Bong, Y.S.4    Daar, I.O.5
  • 26
    • 63049103728 scopus 로고    scopus 로고
    • Fibroblast growth factor receptor-induced phosphorylation of ephrinB1 modulates its interaction with Dishevelled
    • Lee HS, Mood K, Battu G, Ji YJ, Singh A, Daar IO. (2009). Fibroblast growth factor receptor-induced phosphorylation of ephrinB1 modulates its interaction with Dishevelled. Mol Biol Cell 20: 124-133.
    • (2009) Mol Biol Cell , vol.20 , pp. 124-133
    • Lee, H.S.1    Mood, K.2    Battu, G.3    Ji, Y.J.4    Singh, A.5    Daar, I.O.6
  • 27
    • 80052620165 scopus 로고    scopus 로고
    • Smad6-specific recruitment of Smurf E3 ligases mediates TGF-b1-induced degradation of MyD88 in TLR4 signalling
    • Lee YS, Park JS, Kim JH, Jung SM, Lee JY, Kim SJ, Park SH. (2011). Smad6-specific recruitment of Smurf E3 ligases mediates TGF-b1-induced degradation of MyD88 in TLR4 signalling. Nat Commun 2: 460.
    • (2011) Nat Commun , vol.2 , pp. 460
    • Lee, Y.S.1    Park, J.S.2    Kim, J.H.3    Jung, S.M.4    Lee, J.Y.5    Kim, S.J.6    Park, S.H.7
  • 28
    • 0034711290 scopus 로고    scopus 로고
    • Smurf2 is a ubiquitin E3 ligase mediating proteasome-dependent degradation of Smad2 in transforming growth factor-b signaling
    • Lin X, Liang M, Feng XH. (2000). Smurf2 is a ubiquitin E3 ligase mediating proteasome-dependent degradation of Smad2 in transforming growth factor-b signaling. J Biol Chem 275: 36818-36822.
    • (2000) J Biol Chem , vol.275 , pp. 36818-36822
    • Lin, X.1    Liang, M.2    Feng, X.H.3
  • 30
    • 4444276500 scopus 로고    scopus 로고
    • Xenopus paraxial protocadherin has signaling functions and is involved in tissue separation
    • Medina A, Swain RK, Kuerner KM, Steinbeisser H. (2004). Xenopus paraxial protocadherin has signaling functions and is involved in tissue separation. EMBO J 23: 3249-3258.
    • (2004) EMBO J , vol.23 , pp. 3249-3258
    • Medina, A.1    Swain, R.K.2    Kuerner, K.M.3    Steinbeisser, H.4
  • 31
    • 0346503239 scopus 로고    scopus 로고
    • Morphogenetic movements underlying eye field formation require interactions between the FGF and ephrinB1 signaling pathways
    • Moore KB, Mood K, Daar IO, Moody SA. (2004). Morphogenetic movements underlying eye field formation require interactions between the FGF and ephrinB1 signaling pathways. Dev Cell 6: 55-67.
    • (2004) Dev Cell , vol.6 , pp. 55-67
    • Moore, K.B.1    Mood, K.2    Daar, I.O.3    Moody, S.A.4
  • 33
    • 77954956275 scopus 로고    scopus 로고
    • Cellular dynamics in the early mouse embryo: From axis formation to gastrulation
    • Nowotschin S, Hadjantonakis AK. (2010). Cellular dynamics in the early mouse embryo: From axis formation to gastrulation. Curr Opin Genet Dev 20: 420-427.
    • (2010) Curr Opin Genet Dev , vol.20 , pp. 420-427
    • Nowotschin, S.1    Hadjantonakis, A.K.2
  • 34
    • 77949888615 scopus 로고    scopus 로고
    • The ubiquitin binding region of the Smurf HECT domain facilitates polyubiquitylation and binding of ubiquitylated substrates
    • Ogunjimi AA, Wiesner S, Briant DJ, Varelas X, Sicheri F, Forman-Kay J, Wrana JL. (2010). The ubiquitin binding region of the Smurf HECT domain facilitates polyubiquitylation and binding of ubiquitylated substrates. J Biol Chem 285: 6308-6315.
    • (2010) J Biol Chem , vol.285 , pp. 6308-6315
    • Ogunjimi, A.A.1    Wiesner, S.2    Briant, D.J.3    Varelas, X.4    Sicheri, F.5    Forman-Kay, J.6    Wrana, J.L.7
  • 35
    • 55949109059 scopus 로고    scopus 로고
    • The HECT E3 ligase Smurf2 is required for Mad2-dependent spindle assembly checkpoint
    • Osmundson EC, Ray D, Moore FE, Gao Q, Thomsen GH, Kiyokawa H. (2008). The HECT E3 ligase Smurf2 is required for Mad2-dependent spindle assembly checkpoint. J Cell Biol 183: 267-277.
    • (2008) J Cell Biol , vol.183 , pp. 267-277
    • Osmundson, E.C.1    Ray, D.2    Moore, F.E.3    Gao, Q.4    Thomsen, G.H.5    Kiyokawa, H.6
  • 36
    • 14844364701 scopus 로고    scopus 로고
    • Regulation of the polarity protein Par6 by TGFb receptors controls epithelial cell plasticity
    • Ozdamar B, Bose R, Barrios-Rodiles M, Wang HR, Zhang Y, Wrana JL. (2005). Regulation of the polarity protein Par6 by TGFb receptors controls epithelial cell plasticity. Science 307: 1603-1609.
    • (2005) Science , vol.307 , pp. 1603-1609
    • Ozdamar, B.1    Bose, R.2    Barrios-Rodiles, M.3    Wang, H.R.4    Zhang, Y.5    Wrana, J.L.6
  • 37
    • 20344396123 scopus 로고    scopus 로고
    • Eph receptor signalling casts a wide net on cell behaviour
    • Pasquale EB. (2005). Eph receptor signalling casts a wide net on cell behaviour. Nat Rev Mol Cell Biol 6: 462-475.
    • (2005) Nat Rev Mol Cell Biol , vol.6 , pp. 462-475
    • Pasquale, E.B.1
  • 38
    • 41149084179 scopus 로고    scopus 로고
    • Eph-ephrin bidirectional signaling in physiology and disease
    • Pasquale EB. (2008). Eph-ephrin bidirectional signaling in physiology and disease. Cell 133: 38-52.
    • (2008) Cell , vol.133 , pp. 38-52
    • Pasquale, E.B.1
  • 39
    • 79953714884 scopus 로고    scopus 로고
    • EphrinB/EphB signaling controls embryonic germ layer separation by contact-induced cell detachment
    • Rohani N, Canty L, Luu O, Fagotto F, Winklbauer R. (2011). EphrinB/EphB signaling controls embryonic germ layer separation by contact-induced cell detachment. PLoS Biol 9: e1000597.
    • (2011) PLoS Biol , vol.9
    • Rohani, N.1    Canty, L.2    Luu, O.3    Fagotto, F.4    Winklbauer, R.5
  • 40
    • 67349132223 scopus 로고    scopus 로고
    • Physiological functions of the HECT family of ubiquitin ligases
    • Rotin D, Kumar S. (2009). Physiological functions of the HECT family of ubiquitin ligases. Nat Rev Mol Cell Biol 10: 398-409.
    • (2009) Nat Rev Mol Cell Biol , vol.10 , pp. 398-409
    • Rotin, D.1    Kumar, S.2
  • 41
    • 83555174793 scopus 로고    scopus 로고
    • TGFb and BMP-2 regulate epicardial cell invasion via TGFbR3 activation of the Par6/Smurf1/RhoA pathway
    • Sanchez NS, Barnett JV. (2012). TGFb and BMP-2 regulate epicardial cell invasion via TGFbR3 activation of the Par6/Smurf1/RhoA pathway. Cell Signal 24: 539-548.
    • (2012) Cell Signal , vol.24 , pp. 539-548
    • Sanchez, N.S.1    Barnett, J.V.2
  • 42
    • 33947116450 scopus 로고    scopus 로고
    • Ubiquitination of the GTPase Rap1B by the ubiquitin ligase Smurf2 is required for the establishment of neuronal polarity
    • Schwamborn JC, Muller M, Becker AH, Puschel AW. (2007). Ubiquitination of the GTPase Rap1B by the ubiquitin ligase Smurf2 is required for the establishment of neuronal polarity. EMBO J 26: 1410-1422.
    • (2007) EMBO J , vol.26 , pp. 1410-1422
    • Schwamborn, J.C.1    Muller, M.2    Becker, A.H.3    Puschel, A.W.4
  • 43
    • 0037450709 scopus 로고    scopus 로고
    • Association of Dishevelled with Eph tyrosine kinase receptor and ephrin mediates cell repulsion
    • Tanaka M, Kamo T, Ota S, Sugimura H. (2003). Association of Dishevelled with Eph tyrosine kinase receptor and ephrin mediates cell repulsion. EMBO J 22: 847-858.
    • (2003) EMBO J , vol.22 , pp. 847-858
    • Tanaka, M.1    Kamo, T.2    Ota, S.3    Sugimura, H.4
  • 44
  • 45
    • 79960359069 scopus 로고    scopus 로고
    • Binding of RhoA by the C2 domain of E3 ligase Smurf1 is essential for Smurf1-regulated RhoA ubiquitination and cell protrusive activity
    • Tian M, Bai C, Lin Q, Lin H, Liu M, Ding F, Wang HR. (2011). Binding of RhoA by the C2 domain of E3 ligase Smurf1 is essential for Smurf1-regulated RhoA ubiquitination and cell protrusive activity. FEBS Lett 585: 2199-2204.
    • (2011) FEBS Lett , vol.585 , pp. 2199-2204
    • Tian, M.1    Bai, C.2    Lin, Q.3    Lin, H.4    Liu, M.5    Ding, F.6    Wang, H.R.7
  • 46
    • 4444239003 scopus 로고    scopus 로고
    • Paraxial protocadherin coordinates cell polarity during convergent extension via RhoA and JNK
    • Unterseher F, Hefele JA, Giehl K, De Robertis EM, Wedlich D, Schambony A. (2004). Paraxial protocadherin coordinates cell polarity during convergent extension via RhoA and JNK. EMBO J 23: 3259-3269.
    • (2004) EMBO J , vol.23 , pp. 3259-3269
    • Unterseher, F.1    Hefele, J.A.2    Giehl, K.3    De Robertis, E.M.4    Wedlich, D.5    Schambony, A.6
  • 47
    • 0034663226 scopus 로고    scopus 로고
    • Development and control of tissue separation at gastrulation in Xenopus
    • Wacker S, Grimm K, Joos T, Winklbauer R. (2000). Development and control of tissue separation at gastrulation in Xenopus. Dev Biol 224: 428-439.
    • (2000) Dev Biol , vol.224 , pp. 428-439
    • Wacker, S.1    Grimm, K.2    Joos, T.3    Winklbauer, R.4
  • 49
    • 61849166252 scopus 로고    scopus 로고
    • PTPases: 'Eph' ective arbitrators of attraction
    • Wang BC. (2008). PTPases: 'Eph' ective arbitrators of attraction. Blood 112: 455-456.
    • (2008) Blood , vol.112 , pp. 455-456
    • Wang, B.C.1
  • 53
    • 0037527744 scopus 로고    scopus 로고
    • Involvement of the small GTPases XRhoA and XRnd1 in cell adhesion and head formation in early Xenopus development
    • Wunnenberg-Stapleton K, Blitz IL, Hashimoto C, Cho KW. (1999). Involvement of the small GTPases XRhoA and XRnd1 in cell adhesion and head formation in early Xenopus development. Development 126: 5339-5351.
    • (1999) Development , vol.126 , pp. 5339-5351
    • Wunnenberg-Stapleton, K.1    Blitz, I.L.2    Hashimoto, C.3    Cho, K.W.4
  • 54
    • 17044414102 scopus 로고    scopus 로고
    • Ubiquitin ligase Smurf1 controls osteoblast activity and bone homeostasis by targeting MEKK2 for degradation
    • Yamashita M, Ying SX, Zhang GM, Li C, Cheng SY, Deng CX, Zhang YE. (2005). Ubiquitin ligase Smurf1 controls osteoblast activity and bone homeostasis by targeting MEKK2 for degradation. Cell 121: 101-113.
    • (2005) Cell , vol.121 , pp. 101-113
    • Yamashita, M.1    Ying, S.X.2    Zhang, G.M.3    Li, C.4    Cheng, S.Y.5    Deng, C.X.6    Zhang, Y.E.7
  • 55
    • 67649210240 scopus 로고    scopus 로고
    • Smurf2 participates in human trophoblast cell invasion by inhibiting TGF-b type I receptor
    • Yang Q, Chen SP, Zhang XP, Wang H, Zhu C, Lin HY. (2009). Smurf2 participates in human trophoblast cell invasion by inhibiting TGF-b type I receptor. J Histochem Cytochem 57: 605-612.
    • (2009) J Histochem Cytochem , vol.57 , pp. 605-612
    • Yang, Q.1    Chen, S.P.2    Zhang, X.P.3    Wang, H.4    Zhu, C.5    Lin, H.Y.6
  • 56
    • 0033549789 scopus 로고    scopus 로고
    • A SMAD ubiquitin ligase targets the BMP pathway and affects embryonic pattern formation
    • Zhu H, Kavsak P, Abdollah S, Wrana JL, Thomsen GH. (1999). A SMAD ubiquitin ligase targets the BMP pathway and affects embryonic pattern formation. Nature 400: 687-693.
    • (1999) Nature , vol.400 , pp. 687-693
    • Zhu, H.1    Kavsak, P.2    Abdollah, S.3    Wrana, J.L.4    Thomsen, G.H.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.