Involvement of the γ-secretase-mediated EphA4 signaling pathway in synaptic pathogenesis of Alzheimer's disease

Brain Pathology

Volumn 22, Issue 6, 2012, Pages 776-787

  Matsui, Chiyuki ^a   Inoue, Eiji ^a   Kakita, Akiyoshi ^b   Arita, Kohei ^a   Deguchi Tawarada, Maki ^a   Togawa, Aki ^a   Yamada, Akio ^a   Takai, Yoshimi ^c   Takahashi, Hitoshi ^b  

^a KAN Research Institute ^*  (Japan)

^b NIIGATA UNIVERSITY   (Japan)

^c KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

secretase; Alzheimer's disease; dendritic spine; EphA4; Rac

Indexed keywords

EPHRIN RECEPTOR A4; GAMMA SECRETASE; POSTSYNAPTIC DENSITY PROTEIN 95; RAC1 PROTEIN; TAU PROTEIN;

AGED; ALZHEIMER DISEASE; ARTICLE; CHEMICAL ANALYSIS; CONTROLLED STUDY; CORRELATIONAL STUDY; FEMALE; FRONTAL LOBE; HUMAN; HUMAN TISSUE; MALE; NERVE CELL MEMBRANE; NEUROFIBRILLARY TANGLE; PATHOGENESIS; PROTEIN BLOOD LEVEL; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; SYNAPSE;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; BLOTTING, WESTERN; BRAIN; HUMANS; RATS; RECEPTOR, EPHA4; SIGNAL TRANSDUCTION; SYNAPSES;

EID: 84867573082     PISSN: 10156305     EISSN: 17503639     Source Type: Journal    
DOI: 10.1111/j.1750-3639.2012.00587.x     Document Type: Article

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