Crosstalk of the EphA2 receptor with a serine/threonine phosphatase suppresses the Akt-mTORC1 pathway in cancer cells

Cellular Signalling

Volumn 23, Issue 1, 2011, Pages 201-212

  Yang, Nai Ying ^a   Fernandez, Carlos ^a   Richter, Melanie ^a,d   Xiao, Zhan ^b   Valencia, Fatima ^a   Tice, David A ^b   Pasquale, Elena B ^a,c  

^a BURNHAM INSTITUTE   (United States)

^b MEDIMMUNE   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

Author keywords

Cell growth; Ephrin; Prostate cancer; Tumor suppression

Indexed keywords

EPHRIN RECEPTOR A1; EPHRIN RECEPTOR A2; GUANOSINE TRIPHOSPHATASE; INTEGRIN; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; PROTEIN SERINE THREONINE KINASE; RAS PROTEIN;

ARTICLE; CANCER CELL; CELL GROWTH; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INACTIVATION; ENZYME INHIBITION; ENZYME REGULATION; HUMAN; HUMAN CELL; LIGAND BINDING; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

CELL LINE, TUMOR; EPHRIN-A1; HUMANS; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHOPROTEIN PHOSPHATASES; PHOSPHORYLATION; PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; RAS GTPASE-ACTIVATING PROTEINS; RECEPTOR, EPHA2; SIGNAL TRANSDUCTION;

EID: 77957783252     PISSN: 08986568     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cellsig.2010.09.004     Document Type: Article

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