-
1
-
-
77956976681
-
Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm
-
Biswas SK, Mantovani A. Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm. Nat Immunol (2010) 11(10):889-96. doi: 10.1038/ni.1937
-
(2010)
Nat Immunol
, vol.11
, Issue.10
, pp. 889-896
-
-
Biswas, S.K.1
Mantovani, A.2
-
2
-
-
0036839143
-
Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes
-
Mantovani A, Sozzani S, Locati M, Allavena P, Sica A. Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes. Trends Immunol (2002) 23(11):549-55. doi:10.1016/S1471-4906(02)02302-5
-
(2002)
Trends Immunol
, vol.23
, Issue.11
, pp. 549-555
-
-
Mantovani, A.1
Sozzani, S.2
Locati, M.3
Allavena, P.4
Sica, A.5
-
3
-
-
56749174940
-
Exploring the full spectrum of macrophage activation
-
Mosser DM, Edwards JP. Exploring the full spectrum of macrophage activation. Nat Rev Immunol (2008) 8(12):958-69. doi:10.1038/nri2448
-
(2008)
Nat Rev Immunol
, vol.8
, Issue.12
, pp. 958-969
-
-
Mosser, D.M.1
Edwards, J.P.2
-
4
-
-
77649220954
-
Mechanisms underlying lineage commitment and plasticity of helper CD4+ T cells
-
O'Shea JJ, Paul WE. Mechanisms underlying lineage commitment and plasticity of helper CD4+ T cells. Science (2010) 327(5969):1098-102. doi:10.1126/science.1178334
-
(2010)
Science
, vol.327
, Issue.5969
, pp. 1098-1102
-
-
O'Shea, J.J.1
Paul, W.E.2
-
5
-
-
12144288237
-
Human IL-23-producing type 1 macrophages promote but IL-10-producing type 2 macrophages subvert immunity to (myco)bacteria
-
Verreck FA, de Boer T, Langenberg DM, Hoeve MA, Kramer M, Vaisberg E, et al. Human IL-23-producing type 1 macrophages promote but IL-10-producing type 2 macrophages subvert immunity to (myco)bacteria. Proc Natl Acad Sci U S A (2004) 101(13):4560-5. doi:10.1073/pnas.0400983101
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, Issue.13
, pp. 4560-4565
-
-
Verreck, F.A.1
de Boer, T.2
Langenberg, D.M.3
Hoeve, M.A.4
Kramer, M.5
Vaisberg, E.6
-
6
-
-
67650485985
-
Alternative activation of macrophages: an immunologic functional perspective
-
Martinez FO, Helming L, Gordon S. Alternative activation of macrophages: an immunologic functional perspective. Annu Rev Immunol (2009) 27:451-83. doi:10.1146/annurev.immunol.021908.132532
-
(2009)
Annu Rev Immunol
, vol.27
, pp. 451-483
-
-
Martinez, F.O.1
Helming, L.2
Gordon, S.3
-
7
-
-
77953268611
-
Alternative activation of macrophages: mechanism and functions
-
Gordon S, Martinez FO. Alternative activation of macrophages: mechanism and functions. Immunity (2010) 32(5):593-604. doi:10.1016/j.immuni.2010.05.007
-
(2010)
Immunity
, vol.32
, Issue.5
, pp. 593-604
-
-
Gordon, S.1
Martinez, F.O.2
-
8
-
-
84873743410
-
M1 and M2 macrophages: oracles of health and disease
-
Mills CD. M1 and M2 macrophages: oracles of health and disease. Crit Rev Immunol (2012) 32(6):463-88. doi:10.1615/CritRevImmunol.v32.i6.10
-
(2012)
Crit Rev Immunol
, vol.32
, Issue.6
, pp. 463-488
-
-
Mills, C.D.1
-
9
-
-
84857883847
-
Macrophage plasticity and polarization: in vivo veritas
-
Sica A, Mantovani A. Macrophage plasticity and polarization: in vivo veritas. J Clin Invest (2012) 122(3):787-95. doi:10.1172/JCI59643
-
(2012)
J Clin Invest
, vol.122
, Issue.3
, pp. 787-795
-
-
Sica, A.1
Mantovani, A.2
-
10
-
-
0037310024
-
The many faces of macrophage activation
-
Mosser DM. The many faces of macrophage activation. J Leukoc Biol (2003) 73(2):209-12. doi:10.1189/jlb.0602325
-
(2003)
J Leukoc Biol
, vol.73
, Issue.2
, pp. 209-212
-
-
Mosser, D.M.1
-
11
-
-
18944375453
-
Arginase-1 and Ym1 are markers for murine, but not human, alternatively activated myeloid cells
-
Raes G, Van den Bergh R, De Baetselier P, Ghassabeh GH, Scotton C, Locati M, et al. Arginase-1 and Ym1 are markers for murine, but not human, alternatively activated myeloid cells. J Immunol (2005) 174(11):6561. doi:10.4049/jimmunol.174.11.6561
-
(2005)
J Immunol
, vol.174
, Issue.11
, pp. 6561
-
-
Raes, G.1
Van den Bergh, R.2
De Baetselier, P.3
Ghassabeh, G.H.4
Scotton, C.5
Locati, M.6
-
12
-
-
28544446111
-
Monocyte and macrophage heterogeneity
-
Gordon S, Taylor PR. Monocyte and macrophage heterogeneity. Nat Rev Immunol (2005) 5(12):953-64. doi:10.1038/nri1733
-
(2005)
Nat Rev Immunol
, vol.5
, Issue.12
, pp. 953-964
-
-
Gordon, S.1
Taylor, P.R.2
-
13
-
-
80052138920
-
Cancer-promoting tumor-associated macrophages: new vistas and open questions
-
Mantovani A, Germano G, Marchesi F, Locatelli M, Biswas SK. Cancer-promoting tumor-associated macrophages: new vistas and open questions. Eur J Immunol (2011) 41(9):2522-5. doi:10.1002/eji.201141894
-
(2011)
Eur J Immunol
, vol.41
, Issue.9
, pp. 2522-2525
-
-
Mantovani, A.1
Germano, G.2
Marchesi, F.3
Locatelli, M.4
Biswas, S.K.5
-
14
-
-
84859464555
-
Orchestration of metabolism by macrophages
-
Biswas SK, Mantovani A. Orchestration of metabolism by macrophages. Cell Metab (2012) 15(4):432-7. doi:10.1016/j.cmet.2011.11.013
-
(2012)
Cell Metab
, vol.15
, Issue.4
, pp. 432-437
-
-
Biswas, S.K.1
Mantovani, A.2
-
15
-
-
84866736117
-
Macrophage polarization and plasticity in health and disease
-
Biswas SK, Chittezhath M, Shalova IN, Lim JY. Macrophage polarization and plasticity in health and disease. Immunol Res (2012) 53(1-3):11-24. doi:10.1007/s12026-012-8291-9
-
(2012)
Immunol Res
, vol.53
, Issue.1-3
, pp. 11-24
-
-
Biswas, S.K.1
Chittezhath, M.2
Shalova, I.N.3
Lim, J.Y.4
-
16
-
-
84901393470
-
The role of macrophage polarization in infectious and inflammatory diseases
-
Labonte AC, Tosello-Trampont AC, Hahn YS. The role of macrophage polarization in infectious and inflammatory diseases. Mol Cells (2014) 37(4):275-85. doi:10.14348/molcells.2014.2374
-
(2014)
Mol Cells
, vol.37
, Issue.4
, pp. 275-285
-
-
Labonte, A.C.1
Tosello-Trampont, A.C.2
Hahn, Y.S.3
-
17
-
-
0034659784
-
M-1/M-2 macrophages and the Th1/Th2 paradigm
-
Mills CD, Kincaid K, Alt JM, Heilman MJ, Hill AM. M-1/M-2 macrophages and the Th1/Th2 paradigm. J Immunol (2000) 164(12):6166-73. doi:10.4049/jimmunol.164.12.6166
-
(2000)
J Immunol
, vol.164
, Issue.12
, pp. 6166-6173
-
-
Mills, C.D.1
Kincaid, K.2
Alt, J.M.3
Heilman, M.J.4
Hill, A.M.5
-
18
-
-
84869097760
-
Influence of low oxygen tensions on macrophage polarization
-
Escribese MM, Casas M, Corbi AL. Influence of low oxygen tensions on macrophage polarization. Immunobiology (2012) 217(12):1233-40. doi:10.1016/j.imbio.2012.07.002
-
(2012)
Immunobiology
, vol.217
, Issue.12
, pp. 1233-1240
-
-
Escribese, M.M.1
Casas, M.2
Corbi, A.L.3
-
19
-
-
33845752914
-
p50 nuclear factor-kappaB overexpression in tumor-associated macrophages inhibits M1 inflammatory responses and antitumor resistance
-
Saccani A, Schioppa T, Porta C, Biswas SK, Nebuloni M, Vago L, et al. p50 nuclear factor-kappaB overexpression in tumor-associated macrophages inhibits M1 inflammatory responses and antitumor resistance. Cancer Res (2006) 66(23):11432-40. doi:10.1158/0008-5472.CAN-06-1867
-
(2006)
Cancer Res
, vol.66
, Issue.23
, pp. 11432-11440
-
-
Saccani, A.1
Schioppa, T.2
Porta, C.3
Biswas, S.K.4
Nebuloni, M.5
Vago, L.6
-
20
-
-
17144398046
-
Redirecting in vivo elicited tumor infiltrating macrophages and dendritic cells towards tumor rejection
-
Guiducci C, Vicari AP, Sangaletti S, Trinchieri G, Colombo MP. Redirecting in vivo elicited tumor infiltrating macrophages and dendritic cells towards tumor rejection. Cancer Res (2005) 65(8):3437-46.
-
(2005)
Cancer Res
, vol.65
, Issue.8
, pp. 3437-3446
-
-
Guiducci, C.1
Vicari, A.P.2
Sangaletti, S.3
Trinchieri, G.4
Colombo, M.P.5
-
21
-
-
79951671510
-
IRF5 promotes inflammatory macrophage polarization and TH1-TH17 responses
-
Krausgruber T, Blazek K, Smallie T, Alzabin S, Lockstone H, Sahgal N, et al. IRF5 promotes inflammatory macrophage polarization and TH1-TH17 responses. Nat Immunol (2011) 12(3):231-8. doi:10.1038/ni.1990
-
(2011)
Nat Immunol
, vol.12
, Issue.3
, pp. 231-238
-
-
Krausgruber, T.1
Blazek, K.2
Smallie, T.3
Alzabin, S.4
Lockstone, H.5
Sahgal, N.6
-
22
-
-
69449085100
-
GM-CSF- and M-CSF-dependent macrophage phenotypes display differential dependence on type I interferon signaling
-
Fleetwood AJ, Dinh H, Cook AD, Hertzog PJ, Hamilton JA. GM-CSF- and M-CSF-dependent macrophage phenotypes display differential dependence on type I interferon signaling. J Leukoc Biol (2009) 86(2):411-21. doi:10.1189/jlb.1108702
-
(2009)
J Leukoc Biol
, vol.86
, Issue.2
, pp. 411-421
-
-
Fleetwood, A.J.1
Dinh, H.2
Cook, A.D.3
Hertzog, P.J.4
Hamilton, J.A.5
-
23
-
-
84907029444
-
Modulation of TNF-Induced Macrophage Polarization by Synovial Fibroblasts
-
Donlin LT, Jayatilleke A, Giannopoulou EG, Kalliolias GD, Ivashkiv LB. Modulation of TNF-Induced Macrophage Polarization by Synovial Fibroblasts. J Immunol (2014) 193(5):2373-83. doi:10.4049/jimmunol.1400486
-
(2014)
J Immunol
, vol.193
, Issue.5
, pp. 2373-2383
-
-
Donlin, L.T.1
Jayatilleke, A.2
Giannopoulou, E.G.3
Kalliolias, G.D.4
Ivashkiv, L.B.5
-
24
-
-
84896708107
-
Toll like receptor (TLR)-4 as a regulator of peripheral endogenous opioid-mediated analgesia in inflammation
-
Sauer RS, Hackel D, Morschel L, Sahlbach H, Wang Y, Mousa SA, et al. Toll like receptor (TLR)-4 as a regulator of peripheral endogenous opioid-mediated analgesia in inflammation. Mol Pain (2014) 10(1):10. doi:10.1186/1744-8069-10-10
-
(2014)
Mol Pain
, vol.10
, Issue.1
, pp. 10
-
-
Sauer, R.S.1
Hackel, D.2
Morschel, L.3
Sahlbach, H.4
Wang, Y.5
Mousa, S.A.6
-
25
-
-
84868026167
-
Toll-like receptor 4 deficiency promotes the alternative activation of adipose tissue macrophages
-
Orr JS, Puglisi MJ, Ellacott KL, Lumeng CN, Wasserman DH, Hasty AH. Toll-like receptor 4 deficiency promotes the alternative activation of adipose tissue macrophages. Diabetes (2012) 61(11):2718-27. doi:10.2337/db11-1595
-
(2012)
Diabetes
, vol.61
, Issue.11
, pp. 2718-2727
-
-
Orr, J.S.1
Puglisi, M.J.2
Ellacott, K.L.3
Lumeng, C.N.4
Wasserman, D.H.5
Hasty, A.H.6
-
26
-
-
36849033963
-
TAM receptors are pleiotropic inhibitors of the innate immune response
-
Rothlin CV, Ghosh S, Zuniga EI, Oldstone MB, Lemke G. TAM receptors are pleiotropic inhibitors of the innate immune response. Cell (2007) 131(6):1124-36. doi:10.1016/j.cell.2007.10.034
-
(2007)
Cell
, vol.131
, Issue.6
, pp. 1124-1136
-
-
Rothlin, C.V.1
Ghosh, S.2
Zuniga, E.I.3
Oldstone, M.B.4
Lemke, G.5
-
27
-
-
0037178785
-
IRAK-M is a negative regulator of Toll-like receptor signaling
-
Kobayashi K, Hernandez LD, Galan JE, Janeway CA Jr., Medzhitov R, Flavell RA. IRAK-M is a negative regulator of Toll-like receptor signaling. Cell (2002) 110(2):191-202. doi:10.1016/S0092-8674(02)00827-9
-
(2002)
Cell
, vol.110
, Issue.2
, pp. 191-202
-
-
Kobayashi, K.1
Hernandez, L.D.2
Galan, J.E.3
Janeway Jr., C.A.4
Medzhitov, R.5
Flavell, R.A.6
-
28
-
-
20644450804
-
Negative regulation of toll-like receptor-mediated immune responses
-
Liew FY, Xu D, Brint EK, O'Neill LA. Negative regulation of toll-like receptor-mediated immune responses. Nat Rev Immunol (2005) 5(6):446-58. doi:10.1038/nri1630
-
(2005)
Nat Rev Immunol
, vol.5
, Issue.6
, pp. 446-458
-
-
Liew, F.Y.1
Xu, D.2
Brint, E.K.3
O'Neill, L.A.4
-
29
-
-
26644437199
-
SHIP represses the generation of alternatively activated macrophages
-
Rauh MJ, Ho V, Pereira C, Sham A, Sly LM, Lam V, et al. SHIP represses the generation of alternatively activated macrophages. Immunity (2005) 23(4):361-74. doi:10.1016/j.immuni.2005.09.003
-
(2005)
Immunity
, vol.23
, Issue.4
, pp. 361-374
-
-
Rauh, M.J.1
Ho, V.2
Pereira, C.3
Sham, A.4
Sly, L.M.5
Lam, V.6
-
30
-
-
70349559403
-
Endotoxin tolerance: new mechanisms, molecules and clinical significance
-
Biswas SK, Lopez-Collazo E. Endotoxin tolerance: new mechanisms, molecules and clinical significance. Trends Immunol (2009) 30(10):475-87. doi:10.1016/j.it.2009.07.009
-
(2009)
Trends Immunol
, vol.30
, Issue.10
, pp. 475-487
-
-
Biswas, S.K.1
Lopez-Collazo, E.2
-
31
-
-
80055096913
-
Suppressor of cytokine signaling (SOCS)1 is a key determinant of differential macrophage activation and function
-
Whyte CS, Bishop ET, Ruckerl D, Gaspar-Pereira S, Barker RN, Allen JE, et al. Suppressor of cytokine signaling (SOCS)1 is a key determinant of differential macrophage activation and function. J Leukoc Biol (2011) 90(5):845-54. doi:10.1189/jlb.1110644
-
(2011)
J Leukoc Biol
, vol.90
, Issue.5
, pp. 845-854
-
-
Whyte, C.S.1
Bishop, E.T.2
Ruckerl, D.3
Gaspar-Pereira, S.4
Barker, R.N.5
Allen, J.E.6
-
32
-
-
44449140105
-
Unique expression of suppressor of cytokine signaling 3 is essential for classical macrophage activation in rodents in vitro and in vivo
-
Liu Y, Stewart KN, Bishop E, Marek CJ, Kluth DC, Rees AJ, et al. Unique expression of suppressor of cytokine signaling 3 is essential for classical macrophage activation in rodents in vitro and in vivo. J Immunol (2008) 180(9):6270-8. doi:10.4049/jimmunol.180.9.6270
-
(2008)
J Immunol
, vol.180
, Issue.9
, pp. 6270-6278
-
-
Liu, Y.1
Stewart, K.N.2
Bishop, E.3
Marek, C.J.4
Kluth, D.C.5
Rees, A.J.6
-
33
-
-
45549109101
-
NOTCH1 up-regulation and signaling involved in Mycobacterium bovis BCG-induced SOCS3 expression in macrophages
-
Narayana Y, Balaji KN. NOTCH1 up-regulation and signaling involved in Mycobacterium bovis BCG-induced SOCS3 expression in macrophages. J Biol Chem (2008) 283(18):12501-11. doi:10.1074/jbc.M709960200
-
(2008)
J Biol Chem
, vol.283
, Issue.18
, pp. 12501-12511
-
-
Narayana, Y.1
Balaji, K.N.2
-
34
-
-
77953752609
-
Notch signaling determines the M1 versus M2 polarization of macrophages in antitumor immune responses
-
Wang YC, He F, Feng F, Liu XW, Dong GY, Qin HY, et al. Notch signaling determines the M1 versus M2 polarization of macrophages in antitumor immune responses. Cancer Res (2010) 70(12):4840-9. doi:10.1158/0008-5472.CAN-10-0269
-
(2010)
Cancer Res
, vol.70
, Issue.12
, pp. 4840-4849
-
-
Wang, Y.C.1
He, F.2
Feng, F.3
Liu, X.W.4
Dong, G.Y.5
Qin, H.Y.6
-
35
-
-
84866528687
-
SOCS3 deficiency promotes M1 macrophage polarization and inflammation
-
Qin H, Holdbrooks AT, Liu Y, Reynolds SL, Yanagisawa LL, Benveniste EN. SOCS3 deficiency promotes M1 macrophage polarization and inflammation. J Immunol (2012) 189(7):3439-48. doi:10.4049/jimmunol.1201168
-
(2012)
J Immunol
, vol.189
, Issue.7
, pp. 3439-3448
-
-
Qin, H.1
Holdbrooks, A.T.2
Liu, Y.3
Reynolds, S.L.4
Yanagisawa, L.L.5
Benveniste, E.N.6
-
36
-
-
0032481383
-
IL-10 inhibits macrophage activation and proliferation by distinct signaling mechanisms: evidence for Stat3-dependent and -independent pathways
-
O'Farrell AM, Liu Y, Moore KW, Mui AL. IL-10 inhibits macrophage activation and proliferation by distinct signaling mechanisms: evidence for Stat3-dependent and -independent pathways. EMBO J (1998) 17(4):1006-18. doi:10.1093/emboj/17.4.1006
-
(1998)
EMBO J
, vol.17
, Issue.4
, pp. 1006-1018
-
-
O'Farrell, A.M.1
Liu, Y.2
Moore, K.W.3
Mui, A.L.4
-
37
-
-
0036721716
-
Shaping gene expression in activated and resting primary macrophages by IL-10
-
Lang R, Patel D, Morris JJ, Rutschman RL, Murray PJ. Shaping gene expression in activated and resting primary macrophages by IL-10. J Immunol (2002) 169(5):2253-63. doi:10.4049/jimmunol.169.5.2253
-
(2002)
J Immunol
, vol.169
, Issue.5
, pp. 2253-2263
-
-
Lang, R.1
Patel, D.2
Morris, J.J.3
Rutschman, R.L.4
Murray, P.J.5
-
38
-
-
0033010373
-
The IL-4 receptor: signaling mechanisms and biologic functions
-
Nelms K, Keegan AD, Zamorano J, Ryan JJ, Paul WE. The IL-4 receptor: signaling mechanisms and biologic functions. Annu Rev Immunol (1999) 17:701-38. doi:10.1146/annurev.immunol.17.1.701
-
(1999)
Annu Rev Immunol
, vol.17
, pp. 701-738
-
-
Nelms, K.1
Keegan, A.D.2
Zamorano, J.3
Ryan, J.J.4
Paul, W.E.5
-
39
-
-
77952997178
-
Control of macrophage activation and function by PPARs
-
Chawla A. Control of macrophage activation and function by PPARs. Circ Res (2010) 106(10):1559-69. doi:10.1161/CIRCRESAHA.110.216523
-
(2010)
Circ Res
, vol.106
, Issue.10
, pp. 1559-1569
-
-
Chawla, A.1
-
40
-
-
34547492488
-
PPARgamma activation primes human monocytes into alternative M2 macrophages with anti-inflammatory properties
-
Bouhlel MA, Derudas B, Rigamonti E, Dievart R, Brozek J, Haulon S, et al. PPARgamma activation primes human monocytes into alternative M2 macrophages with anti-inflammatory properties. Cell Metab (2007) 6(2):137-43. doi:10.1016/j.cmet.2007.06.010
-
(2007)
Cell Metab
, vol.6
, Issue.2
, pp. 137-143
-
-
Bouhlel, M.A.1
Derudas, B.2
Rigamonti, E.3
Dievart, R.4
Brozek, J.5
Haulon, S.6
-
41
-
-
79960021457
-
Kruppel-like factor 4 regulates macrophage polarization
-
Liao X, Sharma N, Kapadia F, Zhou G, Lu Y, Hong H, et al. Kruppel-like factor 4 regulates macrophage polarization. J Clin Invest (2011) 121(7):2736-49. doi:10.1172/JCI45444
-
(2011)
J Clin Invest
, vol.121
, Issue.7
, pp. 2736-2749
-
-
Liao, X.1
Sharma, N.2
Kapadia, F.3
Zhou, G.4
Lu, Y.5
Hong, H.6
-
42
-
-
84870059127
-
Myeloid Kruppel-like factor 4 deficiency augments atherogenesis in ApoE-/- mice - brief report
-
Sharma N, Lu Y, Zhou G, Liao X, Kapil P, Anand P, et al. Myeloid Kruppel-like factor 4 deficiency augments atherogenesis in ApoE-/- mice - brief report. Arterioscler Thromb Vasc Biol (2012) 32(12):2836-8. doi:10.1161/ATVBAHA.112.300471
-
(2012)
Arterioscler Thromb Vasc Biol
, vol.32
, Issue.12
, pp. 2836-2838
-
-
Sharma, N.1
Lu, Y.2
Zhou, G.3
Liao, X.4
Kapil, P.5
Anand, P.6
-
43
-
-
23244451031
-
Conditional knockout of macrophage PPARgamma increases atherosclerosis in C57BL/6 and low-density lipoprotein receptor-deficient mice
-
Babaev VR, Yancey PG, Ryzhov SV, Kon V, Breyer MD, Magnuson MA, et al. Conditional knockout of macrophage PPARgamma increases atherosclerosis in C57BL/6 and low-density lipoprotein receptor-deficient mice. Arterioscler Thromb Vasc Biol (2005) 25(8):1647-53. doi:10.1161/01.ATV.0000173413.31789.1a
-
(2005)
Arterioscler Thromb Vasc Biol
, vol.25
, Issue.8
, pp. 1647-1653
-
-
Babaev, V.R.1
Yancey, P.G.2
Ryzhov, S.V.3
Kon, V.4
Breyer, M.D.5
Magnuson, M.A.6
-
44
-
-
84875658660
-
Genetic programs expressed in resting and IL-4 alternatively activated mouse and human macrophages: similarities and differences
-
Martinez FO, Helming L, Milde R, Varin A, Melgert BN, Draijer C, et al. Genetic programs expressed in resting and IL-4 alternatively activated mouse and human macrophages: similarities and differences. Blood (2013) 121(9):e57-69. doi:10.1182/blood-2012-06-436212
-
(2013)
Blood
, vol.121
, Issue.9
-
-
Martinez, F.O.1
Helming, L.2
Milde, R.3
Varin, A.4
Melgert, B.N.5
Draijer, C.6
-
45
-
-
77951447568
-
Control of RSV-induced lung injury by alternatively activated macrophages is IL-4R alpha-, TLR4-, and IFN-beta-dependent
-
Shirey KA, Pletneva LM, Puche AC, Keegan AD, Prince GA, Blanco JC, et al. Control of RSV-induced lung injury by alternatively activated macrophages is IL-4R alpha-, TLR4-, and IFN-beta-dependent. Mucosal Immunol (2010) 3(3):291-300. doi:10.1038/mi.2010.6
-
(2010)
Mucosal Immunol
, vol.3
, Issue.3
, pp. 291-300
-
-
Shirey, K.A.1
Pletneva, L.M.2
Puche, A.C.3
Keegan, A.D.4
Prince, G.A.5
Blanco, J.C.6
-
46
-
-
84867908227
-
Regulation of inflammation by interleukin-4: a review of "alternatives
-
Luzina IG, Keegan AD, Heller NM, Rook GA, Shea-Donohue T, Atamas SP. Regulation of inflammation by interleukin-4: a review of "alternatives." J Leukoc Biol (2012) 92(4):753-64. doi:10.1189/jlb.0412214
-
(2012)
" J Leukoc Biol
, vol.92
, Issue.4
, pp. 753-764
-
-
Luzina, I.G.1
Keegan, A.D.2
Heller, N.M.3
Rook, G.A.4
Shea-Donohue, T.5
Atamas, S.P.6
-
47
-
-
34347354309
-
Macrophage-specific PPARgamma controls alternative activation and improves insulin resistance
-
Odegaard JI, Ricardo-Gonzalez RR, Goforth MH, Morel CR, Subramanian V, Mukundan L, et al. Macrophage-specific PPARgamma controls alternative activation and improves insulin resistance. Nature (2007) 447(7148):1116-20. doi:10.1038/nature05894
-
(2007)
Nature
, vol.447
, Issue.7148
, pp. 1116-1120
-
-
Odegaard, J.I.1
Ricardo-Gonzalez, R.R.2
Goforth, M.H.3
Morel, C.R.4
Subramanian, V.5
Mukundan, L.6
-
48
-
-
70449094641
-
PPAR-delta senses and orchestrates clearance of apoptotic cells to promote tolerance
-
Mukundan L, Odegaard JI, Morel CR, Heredia JE, Mwangi JW, Ricardo-Gonzalez RR, et al. PPAR-delta senses and orchestrates clearance of apoptotic cells to promote tolerance. Nat Med (2009) 15(11):1266-72. doi:10.1038/nm.2048
-
(2009)
Nat Med
, vol.15
, Issue.11
, pp. 1266-1272
-
-
Mukundan, L.1
Odegaard, J.I.2
Morel, C.R.3
Heredia, J.E.4
Mwangi, J.W.5
Ricardo-Gonzalez, R.R.6
-
49
-
-
79952155359
-
Transcriptional control of adipose lipid handling by IRF4
-
Eguchi J, Wang X, Yu S, Kershaw EE, Chiu PC, Dushay J, et al. Transcriptional control of adipose lipid handling by IRF4. Cell Metab (2011) 13(3):249-59. doi:10.1016/j.cmet.2011.02.005
-
(2011)
Cell Metab
, vol.13
, Issue.3
, pp. 249-259
-
-
Eguchi, J.1
Wang, X.2
Yu, S.3
Kershaw, E.E.4
Chiu, P.C.5
Dushay, J.6
-
50
-
-
22644441976
-
Regulation of macrophage phenotype by long-term exposure to IL-10
-
Park-Min KH, Antoniv TT, Ivashkiv LB. Regulation of macrophage phenotype by long-term exposure to IL-10. Immunobiology (2005) 210(2-4):77-86. doi:10.1016/j.imbio.2005.05.002
-
(2005)
Immunobiology
, vol.210
, Issue.2-4
, pp. 77-86
-
-
Park-Min, K.H.1
Antoniv, T.T.2
Ivashkiv, L.B.3
-
51
-
-
78149409458
-
Hypoxia-inducible factors as essential regulators of inflammation
-
Imtiyaz HZ, Simon MC. Hypoxia-inducible factors as essential regulators of inflammation. Curr Top Microbiol Immunol (2010) 345:105-20. doi:10.1007/82_2010_74
-
(2010)
Curr Top Microbiol Immunol
, vol.345
, pp. 105-120
-
-
Imtiyaz, H.Z.1
Simon, M.C.2
-
52
-
-
77955295091
-
Hypoxia-inducible factor 2alpha regulates macrophage function in mouse models of acute and tumor inflammation
-
Imtiyaz HZ, Williams EP, Hickey MM, Patel SA, Durham AC, Yuan LJ, et al. Hypoxia-inducible factor 2alpha regulates macrophage function in mouse models of acute and tumor inflammation. J Clin Invest (2010) 120(8):2699-714. doi:10.1172/JCI39506
-
(2010)
J Clin Invest
, vol.120
, Issue.8
, pp. 2699-2714
-
-
Imtiyaz, H.Z.1
Williams, E.P.2
Hickey, M.M.3
Patel, S.A.4
Durham, A.C.5
Yuan, L.J.6
-
53
-
-
33746215136
-
Hypoxia modifies the transcriptome of primary human monocytes: modulation of novel immune-related genes and identification of CC-chemokine ligand 20 as a new hypoxia-inducible gene
-
Bosco MC, Puppo M, Santangelo C, Anfosso L, Pfeffer U, Fardin P, et al. Hypoxia modifies the transcriptome of primary human monocytes: modulation of novel immune-related genes and identification of CC-chemokine ligand 20 as a new hypoxia-inducible gene. J Immunol (2006) 177(3):1941-55. doi:10.4049/jimmunol.177.3.1941
-
(2006)
J Immunol
, vol.177
, Issue.3
, pp. 1941-1955
-
-
Bosco, M.C.1
Puppo, M.2
Santangelo, C.3
Anfosso, L.4
Pfeffer, U.5
Fardin, P.6
-
54
-
-
68249140395
-
Hypoxia-inducible factors 1 and 2 are important transcriptional effectors in primary macrophages experiencing hypoxia
-
Fang HY, Hughes R, Murdoch C, Coffelt SB, Biswas SK, Harris AL, et al. Hypoxia-inducible factors 1 and 2 are important transcriptional effectors in primary macrophages experiencing hypoxia. Blood (2009) 114(4):844-59. doi:10.1182/blood-2008-12-195941
-
(2009)
Blood
, vol.114
, Issue.4
, pp. 844-859
-
-
Fang, H.Y.1
Hughes, R.2
Murdoch, C.3
Coffelt, S.B.4
Biswas, S.K.5
Harris, A.L.6
-
55
-
-
27744472334
-
Macrophage migration and gene expression in response to tumor hypoxia
-
Murdoch C, Lewis CE. Macrophage migration and gene expression in response to tumor hypoxia. Int J Cancer (2005) 117(5):701-8. doi:10.1002/ijc.21422
-
(2005)
Int J Cancer
, vol.117
, Issue.5
, pp. 701-708
-
-
Murdoch, C.1
Lewis, C.E.2
-
56
-
-
0037423948
-
HIF-1alpha is essential for myeloid cell-mediated inflammation
-
Cramer T, Yamanishi Y, Clausen BE, Forster I, Pawlinski R, Mackman N, et al. HIF-1alpha is essential for myeloid cell-mediated inflammation. Cell (2003) 112(5):645-57. doi:10.1016/S0092-8674(03)00154-5
-
(2003)
Cell
, vol.112
, Issue.5
, pp. 645-657
-
-
Cramer, T.1
Yamanishi, Y.2
Clausen, B.E.3
Forster, I.4
Pawlinski, R.5
Mackman, N.6
-
57
-
-
44849100198
-
NF-kappaB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1alpha
-
Rius J, Guma M, Schachtrup C, Akassoglou K, Zinkernagel AS, Nizet V, et al. NF-kappaB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1alpha. Nature (2008) 453(7196):807-11. doi:10.1038/nature06905
-
(2008)
Nature
, vol.453
, Issue.7196
, pp. 807-811
-
-
Rius, J.1
Guma, M.2
Schachtrup, C.3
Akassoglou, K.4
Zinkernagel, A.S.5
Nizet, V.6
-
58
-
-
70249099576
-
Interdependence of hypoxic and innate immune responses
-
Nizet V, Johnson RS. Interdependence of hypoxic and innate immune responses. Nat Rev Immunol (2009) 9(9):609-17. doi:10.1038/nri2607
-
(2009)
Nat Rev Immunol
, vol.9
, Issue.9
, pp. 609-617
-
-
Nizet, V.1
Johnson, R.S.2
-
59
-
-
84907223092
-
Functional polarization of tumour-associated macrophages by tumour-derived lactic acid
-
Colegio OR, Chu NQ, Szabo AL, Chu T, Rhebergen AM, Jairam V, et al. Functional polarization of tumour-associated macrophages by tumour-derived lactic acid. Nature (2014) 513(7519):559-63. doi:10.1038/nature13490
-
(2014)
Nature
, vol.513
, Issue.7519
, pp. 559-563
-
-
Colegio, O.R.1
Chu, N.Q.2
Szabo, A.L.3
Chu, T.4
Rhebergen, A.M.5
Jairam, V.6
-
60
-
-
84906280651
-
Macrophages are recruited to hypoxic tumor areas and acquire a pro-angiogenic M2-Polarized phenotype via hypoxic cancer cell derived cytokines Oncostatin M and Eotaxin
-
Tripathi C, Tewari BN, Kanchan RK, Baghel KS, Nautiyal N, Shrivastava R, et al. Macrophages are recruited to hypoxic tumor areas and acquire a pro-angiogenic M2-Polarized phenotype via hypoxic cancer cell derived cytokines Oncostatin M and Eotaxin. Oncotarget (2014) 5(14):5350-68.
-
(2014)
Oncotarget
, vol.5
, Issue.14
, pp. 5350-5368
-
-
Tripathi, C.1
Tewari, B.N.2
Kanchan, R.K.3
Baghel, K.S.4
Nautiyal, N.5
Shrivastava, R.6
-
61
-
-
77649177217
-
Differential activation and antagonistic function of HIF-{alpha} isoforms in macrophages are essential for NO homeostasis
-
Takeda N, O'Dea EL, Doedens A, Kim JW, Weidemann A, Stockmann C, et al. Differential activation and antagonistic function of HIF-{alpha} isoforms in macrophages are essential for NO homeostasis. Genes Dev (2010) 24(5):491-501. doi:10.1101/gad.1881410
-
(2010)
Genes Dev
, vol.24
, Issue.5
, pp. 491-501
-
-
Takeda, N.1
O'Dea, E.L.2
Doedens, A.3
Kim, J.W.4
Weidemann, A.5
Stockmann, C.6
-
62
-
-
79959526029
-
Microglia: key innate immune cells of the brain
-
Kofler J, Wiley CA. Microglia: key innate immune cells of the brain. Toxicol Pathol (2011) 39(1):103-14. doi:10.1177/0192623310387619
-
(2011)
Toxicol Pathol
, vol.39
, Issue.1
, pp. 103-114
-
-
Kofler, J.1
Wiley, C.A.2
-
63
-
-
79751512463
-
The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance
-
Vandanmagsar B, Youm YH, Ravussin A, Galgani JE, Stadler K, Mynatt RL, et al. The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance. Nat Med (2011) 17(2):179-88. doi:10.1038/nm.2279
-
(2011)
Nat Med
, vol.17
, Issue.2
, pp. 179-188
-
-
Vandanmagsar, B.1
Youm, Y.H.2
Ravussin, A.3
Galgani, J.E.4
Stadler, K.5
Mynatt, R.L.6
-
64
-
-
0037312509
-
NALPs: a novel protein family involved in inflammation
-
Tschopp J, Martinon F, Burns K. NALPs: a novel protein family involved in inflammation. Nat Rev Mol Cell Biol (2003) 4(2):95-104. doi:10.1038/nrm1019
-
(2003)
Nat Rev Mol Cell Biol
, vol.4
, Issue.2
, pp. 95-104
-
-
Tschopp, J.1
Martinon, F.2
Burns, K.3
-
65
-
-
0036671894
-
The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta
-
Martinon F, Burns K, Tschopp J. The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta. Mol Cell (2002) 10(2):417-26. doi:10.1016/S1097-2765(02)00599-3
-
(2002)
Mol Cell
, vol.10
, Issue.2
, pp. 417-426
-
-
Martinon, F.1
Burns, K.2
Tschopp, J.3
-
66
-
-
17644366913
-
NOD-LRR proteins: role in host-microbial interactions and inflammatory disease
-
Inohara N, Chamaillard M, McDonald C, Nuñez G. NOD-LRR proteins: role in host-microbial interactions and inflammatory disease. Ann Rev Biochem (2005) 74:355-83. doi:10.1146/annurev.biochem.74.082803.133347
-
(2005)
Ann Rev Biochem
, vol.74
, pp. 355-383
-
-
Inohara, N.1
Chamaillard, M.2
McDonald, C.3
Nuñez, G.4
-
67
-
-
48549102504
-
NOD-like receptors (NLRs): bona fide intracellular microbial sensors
-
Shaw MH, Reimer T, Kim YG, Nunez G. NOD-like receptors (NLRs): bona fide intracellular microbial sensors. Curr Opin Immunol (2008) 20(4):377-82. doi:10.1016/j.coi.2008.06.001
-
(2008)
Curr Opin Immunol
, vol.20
, Issue.4
, pp. 377-382
-
-
Shaw, M.H.1
Reimer, T.2
Kim, Y.G.3
Nunez, G.4
-
68
-
-
0038824980
-
An essential role for NOD1 in host recognition of bacterial peptidoglycan containing diaminopimelic acid
-
Chamaillard M, Hashimoto M, Horie Y, Masumoto J, Qiu S, Saab L, et al. An essential role for NOD1 in host recognition of bacterial peptidoglycan containing diaminopimelic acid. Nat Immunol (2003) 4(7):702-7. doi:10.1038/ni945
-
(2003)
Nat Immunol
, vol.4
, Issue.7
, pp. 702-707
-
-
Chamaillard, M.1
Hashimoto, M.2
Horie, Y.3
Masumoto, J.4
Qiu, S.5
Saab, L.6
-
69
-
-
0012722659
-
Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection
-
Girardin SE, Boneca IG, Viala J, Chamaillard M, Labigne A, Thomas G, et al. Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection. J Biol Chem (2003) 278(11):8869-72. doi:10.1074/jbc.C200651200
-
(2003)
J Biol Chem
, vol.278
, Issue.11
, pp. 8869-8872
-
-
Girardin, S.E.1
Boneca, I.G.2
Viala, J.3
Chamaillard, M.4
Labigne, A.5
Thomas, G.6
-
70
-
-
38549084725
-
A critical role of RICK/RIP2 polyubiquitination in Nod-induced NF-kappaB activation
-
Hasegawa M, Fujimoto Y, Lucas PC, Nakano H, Fukase K, Nunez G, et al. A critical role of RICK/RIP2 polyubiquitination in Nod-induced NF-kappaB activation. EMBO J (2008) 27(2):373-83. doi:10.1038/sj.emboj.7601962
-
(2008)
EMBO J
, vol.27
, Issue.2
, pp. 373-383
-
-
Hasegawa, M.1
Fujimoto, Y.2
Lucas, P.C.3
Nakano, H.4
Fukase, K.5
Nunez, G.6
-
71
-
-
40449136493
-
The ubiquitin-editing enzyme A20 restricts nucleotide-binding oligomerization domain containing 2-triggered signals
-
Hitotsumatsu O, Ahmad RC, Tavares R, Wang M, Philpott D, Turer EE, et al. The ubiquitin-editing enzyme A20 restricts nucleotide-binding oligomerization domain containing 2-triggered signals. Immunity (2008) 28(3):381-90. doi:10.1016/j.immuni.2008.02.002
-
(2008)
Immunity
, vol.28
, Issue.3
, pp. 381-390
-
-
Hitotsumatsu, O.1
Ahmad, R.C.2
Tavares, R.3
Wang, M.4
Philpott, D.5
Turer, E.E.6
-
72
-
-
84876282419
-
Manipulation of small Rho GTPases is a pathogen-induced process detected by NOD1
-
Keestra AM, Winter MG, Auburger JJ, Frassle SP, Xavier MN, Winter SE, et al. Manipulation of small Rho GTPases is a pathogen-induced process detected by NOD1. Nature (2013) 496(7444):233-7. doi:10.1038/nature12025
-
(2013)
Nature
, vol.496
, Issue.7444
, pp. 233-237
-
-
Keestra, A.M.1
Winter, M.G.2
Auburger, J.J.3
Frassle, S.P.4
Xavier, M.N.5
Winter, S.E.6
-
73
-
-
48449102092
-
The structure of the GM-CSF receptor complex reveals a distinct mode of cytokine receptor activation
-
Hansen G, Hercus TR, McClure BJ, Stomski FC, Dottore M, Powell J, et al. The structure of the GM-CSF receptor complex reveals a distinct mode of cytokine receptor activation. Cell (2008) 134(3):496-507. doi:10.1016/j.cell.2008.05.053
-
(2008)
Cell
, vol.134
, Issue.3
, pp. 496-507
-
-
Hansen, G.1
Hercus, T.R.2
McClure, B.J.3
Stomski, F.C.4
Dottore, M.5
Powell, J.6
-
74
-
-
34548448100
-
Gene expression profiling during differentiation of human monocytes to macrophages or dendritic cells
-
Lehtonen A, Ahlfors H, Veckman V, Miettinen M, Lahesmaa R, Julkunen I. Gene expression profiling during differentiation of human monocytes to macrophages or dendritic cells. J Leukoc Biol (2007) 82(3):710-20. doi:10.1189/jlb.0307194
-
(2007)
J Leukoc Biol
, vol.82
, Issue.3
, pp. 710-720
-
-
Lehtonen, A.1
Ahlfors, H.2
Veckman, V.3
Miettinen, M.4
Lahesmaa, R.5
Julkunen, I.6
-
75
-
-
84866662452
-
High-resolution transcriptome of human macrophages
-
Beyer M, Mallmann MR, Xue J, Staratschek-Jox A, Vorholt D, Krebs W, et al. High-resolution transcriptome of human macrophages. PLoS One (2012) 7(9):e45466. doi:10.1371/journal.pone.0045466
-
(2012)
PLoS One
, vol.7
, Issue.9
-
-
Beyer, M.1
Mallmann, M.R.2
Xue, J.3
Staratschek-Jox, A.4
Vorholt, D.5
Krebs, W.6
-
76
-
-
0027538181
-
Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity
-
Dranoff G, Jaffee E, Lazenby A, Golumbek P, Levitsky H, Brose K, et al. Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity. Proc Natl Acad Sci U S A (1993) 90(8):3539-43. doi:10.1073/pnas.90.8.3539
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, Issue.8
, pp. 3539-3543
-
-
Dranoff, G.1
Jaffee, E.2
Lazenby, A.3
Golumbek, P.4
Levitsky, H.5
Brose, K.6
-
77
-
-
0030711559
-
Human pulmonary alveolar proteinosis associated with a defect in GM-CSF/IL-3/IL-5 receptor common beta chain expression
-
Dirksen U, Nishinakamura R, Groneck P, Hattenhorst U, Nogee L, Murray R, et al. Human pulmonary alveolar proteinosis associated with a defect in GM-CSF/IL-3/IL-5 receptor common beta chain expression. J Clin Invest (1997) 100(9):2211-7. doi:10.1172/JCI119758
-
(1997)
J Clin Invest
, vol.100
, Issue.9
, pp. 2211-2217
-
-
Dirksen, U.1
Nishinakamura, R.2
Groneck, P.3
Hattenhorst, U.4
Nogee, L.5
Murray, R.6
-
78
-
-
0032529495
-
Defective expression of granulocyte-macrophage colony-stimulating factor/interleukin-3/interleukin-5 receptor common beta chain in children with acute myeloid leukemia associated with respiratory failure
-
Dirksen U, Hattenhorst U, Schneider P, Schroten H, Gobel U, Bocking A, et al. Defective expression of granulocyte-macrophage colony-stimulating factor/interleukin-3/interleukin-5 receptor common beta chain in children with acute myeloid leukemia associated with respiratory failure. Blood (1998) 92(4):1097-103.
-
(1998)
Blood
, vol.92
, Issue.4
, pp. 1097-1103
-
-
Dirksen, U.1
Hattenhorst, U.2
Schneider, P.3
Schroten, H.4
Gobel, U.5
Bocking, A.6
-
79
-
-
47849125676
-
MicroRNAs: new regulators of immune cell development and function
-
Baltimore D, Boldin MP, O'Connell RM, Rao DS, Taganov KD. MicroRNAs: new regulators of immune cell development and function. Nat Immunol (2008) 9(8):839-45. doi:10.1038/ni.f.209
-
(2008)
Nat Immunol
, vol.9
, Issue.8
, pp. 839-845
-
-
Baltimore, D.1
Boldin, M.P.2
O'Connell, R.M.3
Rao, D.S.4
Taganov, K.D.5
-
80
-
-
84880772300
-
MicroRNA-mediated control of macrophages and its implications for cancer
-
Squadrito ML, Etzrodt M, De Palma M, Pittet MJ. MicroRNA-mediated control of macrophages and its implications for cancer. Trends Immunol (2013) 34(7):350-9. doi:10.1016/j.it.2013.02.003
-
(2013)
Trends Immunol
, vol.34
, Issue.7
, pp. 350-359
-
-
Squadrito, M.L.1
Etzrodt, M.2
De Palma, M.3
Pittet, M.J.4
-
81
-
-
84862697885
-
Identifying functional microRNAs in macrophages with polarized phenotypes
-
Graff JW, Dickson AM, Clay G, McCaffrey AP, Wilson ME. Identifying functional microRNAs in macrophages with polarized phenotypes. J Biol Chem (2012) 287(26):21816-25. doi:10.1074/jbc.M111.327031
-
(2012)
J Biol Chem
, vol.287
, Issue.26
, pp. 21816-21825
-
-
Graff, J.W.1
Dickson, A.M.2
Clay, G.3
McCaffrey, A.P.4
Wilson, M.E.5
-
82
-
-
41149130219
-
Sustained expression of microRNA-155 in hematopoietic stem cells causes a myeloproliferative disorder
-
O'Connell RM, Rao DS, Chaudhuri AA, Boldin MP, Taganov KD, Nicoll J, et al. Sustained expression of microRNA-155 in hematopoietic stem cells causes a myeloproliferative disorder. J Exp Med (2008) 205(3):585-94. doi:10.1084/jem.20072108
-
(2008)
J Exp Med
, vol.205
, Issue.3
, pp. 585-594
-
-
O'Connell, R.M.1
Rao, D.S.2
Chaudhuri, A.A.3
Boldin, M.P.4
Taganov, K.D.5
Nicoll, J.6
-
83
-
-
33747608638
-
NF-kappaB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses
-
Taganov KD, Boldin MP, Chang KJ, Baltimore D. NF-kappaB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses. Proc Natl Acad Sci U S A (2006) 103(33):12481-6. doi:10.1073/pnas.0605298103
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, Issue.33
, pp. 12481-12486
-
-
Taganov, K.D.1
Boldin, M.P.2
Chang, K.J.3
Baltimore, D.4
-
84
-
-
78650210727
-
Bcl-6 and NF-kappaB cistromes mediate opposing regulation of the innate immune response
-
Barish GD, Yu RT, Karunasiri M, Ocampo CB, Dixon J, Benner C, et al. Bcl-6 and NF-kappaB cistromes mediate opposing regulation of the innate immune response. Genes Dev (2010) 24(24):2760-5. doi:10.1101/gad.1998010
-
(2010)
Genes Dev
, vol.24
, Issue.24
, pp. 2760-2765
-
-
Barish, G.D.1
Yu, R.T.2
Karunasiri, M.3
Ocampo, C.B.4
Dixon, J.5
Benner, C.6
-
85
-
-
38049030287
-
Modulation of miR-155 and miR-125b levels following lipopolysaccharide/TNF-alpha stimulation and their possible roles in regulating the response to endotoxin shock
-
Tili E, Michaille JJ, Cimino A, Costinean S, Dumitru CD, Adair B, et al. Modulation of miR-155 and miR-125b levels following lipopolysaccharide/TNF-alpha stimulation and their possible roles in regulating the response to endotoxin shock. J Immunol (2007) 179(8):5082-9. doi:10.4049/jimmunol.179.8.5082
-
(2007)
J Immunol
, vol.179
, Issue.8
, pp. 5082-5089
-
-
Tili, E.1
Michaille, J.J.2
Cimino, A.3
Costinean, S.4
Dumitru, C.D.5
Adair, B.6
-
86
-
-
65249131826
-
Induction and regulatory function of miR-9 in human monocytes and neutrophils exposed to proinflammatory signals
-
Bazzoni F, Rossato M, Fabbri M, Gaudiosi D, Mirolo M, Mori L, et al. Induction and regulatory function of miR-9 in human monocytes and neutrophils exposed to proinflammatory signals. Proc Natl Acad Sci U S A (2009) 106(13):5282-7. doi:10.1073/pnas.0810909106
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, Issue.13
, pp. 5282-5287
-
-
Bazzoni, F.1
Rossato, M.2
Fabbri, M.3
Gaudiosi, D.4
Mirolo, M.5
Mori, L.6
-
87
-
-
84881164436
-
MicroRNA-17/20a/106a modulate macrophage inflammatory responses through targeting signal-regulatory protein alpha
-
Zhu D, Pan C, Li L, Bian Z, Lv Z, Shi L, et al. MicroRNA-17/20a/106a modulate macrophage inflammatory responses through targeting signal-regulatory protein alpha. J Allergy Clin Immunol (2013) 132(2):426e-36e. doi:10.1016/j.jaci.2013.02.005
-
(2013)
J Allergy Clin Immunol
, vol.132
, Issue.2
, pp. 426e-e436
-
-
Zhu, D.1
Pan, C.2
Li, L.3
Bian, Z.4
Lv, Z.5
Shi, L.6
-
88
-
-
79958099199
-
MicroRNA-98 negatively regulates IL-10 production and endotoxin tolerance in macrophages after LPS stimulation
-
Liu Y, Chen Q, Song Y, Lai L, Wang J, Yu H, et al. MicroRNA-98 negatively regulates IL-10 production and endotoxin tolerance in macrophages after LPS stimulation. FEBS Lett (2011) 585(12):1963-8. doi:10.1016/j.febslet.2011.05.029
-
(2011)
FEBS Lett
, vol.585
, Issue.12
, pp. 1963-1968
-
-
Liu, Y.1
Chen, Q.2
Song, Y.3
Lai, L.4
Wang, J.5
Yu, H.6
-
89
-
-
75649113377
-
Negative regulation of TLR4 via targeting of the proinflammatory tumor suppressor PDCD4 by the microRNA miR-21
-
Sheedy FJ, Palsson-McDermott E, Hennessy EJ, Martin C, O'Leary JJ, Ruan Q, et al. Negative regulation of TLR4 via targeting of the proinflammatory tumor suppressor PDCD4 by the microRNA miR-21. Nat Immunol (2010) 11(2):141-7. doi:10.1038/ni.1828
-
(2010)
Nat Immunol
, vol.11
, Issue.2
, pp. 141-147
-
-
Sheedy, F.J.1
Palsson-McDermott, E.2
Hennessy, E.J.3
Martin, C.4
O'Leary, J.J.5
Ruan, Q.6
-
90
-
-
79251592866
-
Mechanistic role of microRNA-146a in endotoxin-induced differential cross-regulation of TLR signaling
-
Nahid MA, Satoh M, Chan EK. Mechanistic role of microRNA-146a in endotoxin-induced differential cross-regulation of TLR signaling. J Immunol (2011) 186(3):1723-34. doi:10.4049/jimmunol.1002311
-
(2011)
J Immunol
, vol.186
, Issue.3
, pp. 1723-1734
-
-
Nahid, M.A.1
Satoh, M.2
Chan, E.K.3
-
91
-
-
78651247933
-
MicroRNA-124 promotes microglia quiescence and suppresses EAE by deactivating macrophages via the C/EBP-alpha-PU.1 pathway
-
Ponomarev ED, Veremeyko T, Barteneva N, Krichevsky AM, Weiner HL. MicroRNA-124 promotes microglia quiescence and suppresses EAE by deactivating macrophages via the C/EBP-alpha-PU.1 pathway. Nat Med (2011) 17(1):64-70. doi:10.1038/nm.2266
-
(2011)
Nat Med
, vol.17
, Issue.1
, pp. 64-70
-
-
Ponomarev, E.D.1
Veremeyko, T.2
Barteneva, N.3
Krichevsky, A.M.4
Weiner, H.L.5
-
92
-
-
84862150859
-
A novel regulator of macrophage activation: miR-223 in obesity-associated adipose tissue inflammation
-
Zhuang G, Meng C, Guo X, Cheruku PS, Shi L, Xu H, et al. A novel regulator of macrophage activation: miR-223 in obesity-associated adipose tissue inflammation. Circulation (2012) 125(23):2892-903. doi:10.1161/CIRCULATIONAHA.111.087817
-
(2012)
Circulation
, vol.125
, Issue.23
, pp. 2892-2903
-
-
Zhuang, G.1
Meng, C.2
Guo, X.3
Cheruku, P.S.4
Shi, L.5
Xu, H.6
-
93
-
-
84879118942
-
MicroRNA let-7c regulates macrophage polarization
-
Banerjee S, Xie N, Cui H, Tan Z, Yang S, Icyuz M, et al. MicroRNA let-7c regulates macrophage polarization. J Immunol (2013) 190(12):6542-9. doi:10.4049/jimmunol.1202496
-
(2013)
J Immunol
, vol.190
, Issue.12
, pp. 6542-6549
-
-
Banerjee, S.1
Xie, N.2
Cui, H.3
Tan, Z.4
Yang, S.5
Icyuz, M.6
-
94
-
-
67449126809
-
Differential role for c-Rel and C/EBPbeta/delta in TLR-mediated induction of proinflammatory cytokines
-
Lu YC, Kim I, Lye E, Shen F, Suzuki N, Suzuki S, et al. Differential role for c-Rel and C/EBPbeta/delta in TLR-mediated induction of proinflammatory cytokines. J Immunol (2009) 182(11):7212-21. doi:10.4049/jimmunol.0802971
-
(2009)
J Immunol
, vol.182
, Issue.11
, pp. 7212-7221
-
-
Lu, Y.C.1
Kim, I.2
Lye, E.3
Shen, F.4
Suzuki, N.5
Suzuki, S.6
-
95
-
-
62849092708
-
Function of C/EBPdelta in a regulatory circuit that discriminates between transient and persistent TLR4-induced signals
-
Litvak V, Ramsey SA, Rust AG, Zak DE, Kennedy KA, Lampano AE, et al. Function of C/EBPdelta in a regulatory circuit that discriminates between transient and persistent TLR4-induced signals. Nat Immunol (2009) 10(4):437-43. doi:10.1038/ni.1721
-
(2009)
Nat Immunol
, vol.10
, Issue.4
, pp. 437-443
-
-
Litvak, V.1
Ramsey, S.A.2
Rust, A.G.3
Zak, D.E.4
Kennedy, K.A.5
Lampano, A.E.6
-
96
-
-
78751483763
-
The interleukin 13 (IL-13) pathway in human macrophages is modulated by microRNA-155 via direct targeting of interleukin 13 receptor alpha1 (IL13Ralpha1)
-
Martinez-Nunez RT, Louafi F, Sanchez-Elsner T. The interleukin 13 (IL-13) pathway in human macrophages is modulated by microRNA-155 via direct targeting of interleukin 13 receptor alpha1 (IL13Ralpha1). J Biol Chem (2011) 286(3):1786-94. doi:10.1074/jbc.M110.169367
-
(2011)
J Biol Chem
, vol.286
, Issue.3
, pp. 1786-1794
-
-
Martinez-Nunez, R.T.1
Louafi, F.2
Sanchez-Elsner, T.3
-
97
-
-
84867420120
-
Re-polarization of tumor-associated macrophages to pro-inflammatory M1 macrophages by microRNA-155
-
Cai X, Yin Y, Li N, Zhu D, Zhang J, Zhang CY, et al. Re-polarization of tumor-associated macrophages to pro-inflammatory M1 macrophages by microRNA-155. J Mol Cell Biol (2012) 4(5):341-3. doi:10.1093/jmcb/mjs044
-
(2012)
J Mol Cell Biol
, vol.4
, Issue.5
, pp. 341-343
-
-
Cai, X.1
Yin, Y.2
Li, N.3
Zhu, D.4
Zhang, J.5
Zhang, C.Y.6
-
98
-
-
77449128568
-
Onco-miR-155 targets SHIP1 to promote TNFalpha-dependent growth of B cell lymphomas
-
Pedersen IM, Otero D, Kao E, Miletic AV, Hother C, Ralfkiaer E, et al. Onco-miR-155 targets SHIP1 to promote TNFalpha-dependent growth of B cell lymphomas. EMBO Mol Med. (2009) 1(5):288-95. doi:10.1002/emmm.200900028
-
(2009)
EMBO Mol Med
, vol.1
, Issue.5
, pp. 288-295
-
-
Pedersen, I.M.1
Otero, D.2
Kao, E.3
Miletic, A.V.4
Hother, C.5
Ralfkiaer, E.6
-
99
-
-
21244503601
-
Bruton's tyrosine kinase is involved in p65-mediated transactivation and phosphorylation of p65 on serine 536 during NFkappaB activation by lipopolysaccharide
-
Doyle SL, Jefferies CA, O'Neill LA. Bruton's tyrosine kinase is involved in p65-mediated transactivation and phosphorylation of p65 on serine 536 during NFkappaB activation by lipopolysaccharide. J Biol Chem (2005) 280(25):23496-501. doi:10.1074/jbc.C500053200
-
(2005)
J Biol Chem
, vol.280
, Issue.25
, pp. 23496-23501
-
-
Doyle, S.L.1
Jefferies, C.A.2
O'Neill, L.A.3
-
100
-
-
37549021148
-
Signaling by Toll-like receptors 8 and 9 requires Bruton's tyrosine kinase
-
Doyle SL, Jefferies CA, Feighery C, O'Neill LA. Signaling by Toll-like receptors 8 and 9 requires Bruton's tyrosine kinase. J Biol Chem (2007) 282(51):36953-60. doi:10.1074/jbc.M707682200
-
(2007)
J Biol Chem
, vol.282
, Issue.51
, pp. 36953-36960
-
-
Doyle, S.L.1
Jefferies, C.A.2
Feighery, C.3
O'Neill, L.A.4
-
101
-
-
0038544296
-
Bruton's tyrosine kinase is required for lipopolysaccharide-induced tumor necrosis factor alpha production
-
Horwood NJ, Mahon T, McDaid JP, Campbell J, Mano H, Brennan FM, et al. Bruton's tyrosine kinase is required for lipopolysaccharide-induced tumor necrosis factor alpha production. J Exp Med (2003) 197(12):1603-11. doi:10.1084/jem.20021845
-
(2003)
J Exp Med
, vol.197
, Issue.12
, pp. 1603-1611
-
-
Horwood, N.J.1
Mahon, T.2
McDaid, J.P.3
Campbell, J.4
Mano, H.5
Brennan, F.M.6
-
102
-
-
33644844972
-
Bruton's tyrosine kinase is required for TLR2 and TLR4-induced TNF, but not IL-6, production
-
Horwood NJ, Page TH, McDaid JP, Palmer CD, Campbell J, Mahon T, et al. Bruton's tyrosine kinase is required for TLR2 and TLR4-induced TNF, but not IL-6, production. J Immunol (2006) 176(6):3635-41. doi:10.4049/jimmunol.176.6.3635
-
(2006)
J Immunol
, vol.176
, Issue.6
, pp. 3635-3641
-
-
Horwood, N.J.1
Page, T.H.2
McDaid, J.P.3
Palmer, C.D.4
Campbell, J.5
Mahon, T.6
-
103
-
-
84908193590
-
Btk regulates macrophage polarization in response to lipopolysaccharide
-
Ni Gabhann J, Hams E, Smith S, Wynne C, Byrne JC, Brennan K, et al. Btk regulates macrophage polarization in response to lipopolysaccharide. PLoS One (2014) 9(1):e85834. doi:10.1371/journal.pone.0085834
-
(2014)
PLoS One
, vol.9
, Issue.1
-
-
Ni Gabhann, J.1
Hams, E.2
Smith, S.3
Wynne, C.4
Byrne, J.C.5
Brennan, K.6
-
104
-
-
84859564599
-
Bruton's tyrosine kinase phosphorylates Toll-like receptor 3 to initiate antiviral response
-
Lee KG, Xu S, Kang ZH, Huo J, Huang M, Liu D, et al. Bruton's tyrosine kinase phosphorylates Toll-like receptor 3 to initiate antiviral response. Proc Natl Acad Sci U S A (2012) 109(15):5791-6. doi:10.1073/pnas.1119238109
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, Issue.15
, pp. 5791-5796
-
-
Lee, K.G.1
Xu, S.2
Kang, Z.H.3
Huo, J.4
Huang, M.5
Liu, D.6
-
105
-
-
84919429177
-
Triggering TLR2 5 and 8 reinforces the restrictive nature of M1- and M2-polarized macrophages to HIV
-
Schlaepfer E, Rochat MA, Duo L, Speck RF. Triggering TLR2, 3, 4, 5 and 8 reinforces the restrictive nature of M1- and M2-polarized macrophages to HIV. J Virol (2014) 88(17):9769-81. doi:10.1128/JVI.01053-14
-
(2014)
J Virol
, vol.88
, Issue.17
, pp. 9769-9781
-
-
Schlaepfer, E.1
Rochat, M.A.2
Duo, L.3
Speck, R.F.4
-
106
-
-
33344460032
-
A distinct and unique transcriptional program expressed by tumor-associated macrophages (defective NF-kappaB and enhanced IRF-3/STAT1 activation)
-
Biswas SK, Gangi L, Paul S, Schioppa T, Saccani A, Sironi M, et al. A distinct and unique transcriptional program expressed by tumor-associated macrophages (defective NF-kappaB and enhanced IRF-3/STAT1 activation). Blood (2006) 107(5):2112-22. doi:10.1182/blood-2005-01-0428
-
(2006)
Blood
, vol.107
, Issue.5
, pp. 2112-2122
-
-
Biswas, S.K.1
Gangi, L.2
Paul, S.3
Schioppa, T.4
Saccani, A.5
Sironi, M.6
-
107
-
-
70349275277
-
Tolerance and M2 (alternative) macrophage polarization are related processes orchestrated by p50 nuclear factor kappaB
-
Porta C, Rimoldi M, Raes G, Brys L, Ghezzi P, Di Liberto D, et al. Tolerance and M2 (alternative) macrophage polarization are related processes orchestrated by p50 nuclear factor kappaB. Proc Natl Acad Sci U S A (2009) 106(35):14978-83. doi:10.1073/pnas.0809784106
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, Issue.35
, pp. 14978-14983
-
-
Porta, C.1
Rimoldi, M.2
Raes, G.3
Brys, L.4
Ghezzi, P.5
Di Liberto, D.6
-
108
-
-
85047693348
-
Severe diabetes, age-dependent loss of adipose tissue, and mild growth deficiency in mice lacking Akt2/PKB beta
-
Garofalo RS, Orena SJ, Rafidi K, Torchia AJ, Stock JL, Hildebrandt AL, et al. Severe diabetes, age-dependent loss of adipose tissue, and mild growth deficiency in mice lacking Akt2/PKB beta. J Clin Invest (2003) 112(2):197-208. doi:10.1172/JCI16885
-
(2003)
J Clin Invest
, vol.112
, Issue.2
, pp. 197-208
-
-
Garofalo, R.S.1
Orena, S.J.2
Rafidi, K.3
Torchia, A.J.4
Stock, J.L.5
Hildebrandt, A.L.6
-
109
-
-
77957260181
-
Identification of a novel macrophage phenotype that develops in response to atherogenic phospholipids via Nrf2
-
Kadl A, Meher AK, Sharma PR, Lee MY, Doran AC, Johnstone SR, et al. Identification of a novel macrophage phenotype that develops in response to atherogenic phospholipids via Nrf2. Circ Res (2010) 107(6):737-46. doi:10.1161/CIRCRESAHA.109.215715
-
(2010)
Circ Res
, vol.107
, Issue.6
, pp. 737-746
-
-
Kadl, A.1
Meher, A.K.2
Sharma, P.R.3
Lee, M.Y.4
Doran, A.C.5
Johnstone, S.R.6
-
110
-
-
46949094641
-
Tumor-infiltrating myeloid-derived suppressor cells are pleiotropic-inflamed monocytes/macrophages that bear M1- and M2-type characteristics
-
Umemura N, Saio M, Suwa T, Kitoh Y, Bai J, Nonaka K, et al. Tumor-infiltrating myeloid-derived suppressor cells are pleiotropic-inflamed monocytes/macrophages that bear M1- and M2-type characteristics. J Leukoc Biol (2008) 83(5):1136-44. doi:10.1189/jlb.0907611
-
(2008)
J Leukoc Biol
, vol.83
, Issue.5
, pp. 1136-1144
-
-
Umemura, N.1
Saio, M.2
Suwa, T.3
Kitoh, Y.4
Bai, J.5
Nonaka, K.6
-
111
-
-
84881478367
-
A long noncoding RNA mediates both activation and repression of immune response genes
-
Carpenter S, Aiello D, Atianand MK, Ricci EP, Gandhi P, Hall LL, et al. A long noncoding RNA mediates both activation and repression of immune response genes. Science (2013) 341(6147):789-92. doi:10.1126/science.1240925
-
(2013)
Science
, vol.341
, Issue.6147
, pp. 789-792
-
-
Carpenter, S.1
Aiello, D.2
Atianand, M.K.3
Ricci, E.P.4
Gandhi, P.5
Hall, L.L.6
-
112
-
-
84892923750
-
The long noncoding RNA THRIL regulates TNFalpha expression through its interaction with hnRNPL
-
Li Z, Chao TC, Chang KY, Lin N, Patil VS, Shimizu C, et al. The long noncoding RNA THRIL regulates TNFalpha expression through its interaction with hnRNPL. Proc Natl Acad Sci U S A (2014) 111(3):1002-7. doi:10.1073/pnas.1313768111
-
(2014)
Proc Natl Acad Sci U S A
, vol.111
, Issue.3
, pp. 1002-1007
-
-
Li, Z.1
Chao, T.C.2
Chang, K.Y.3
Lin, N.4
Patil, V.S.5
Shimizu, C.6
-
113
-
-
64849097221
-
Alternatively activated macrophages elicited by helminth infection can be reprogrammed to enable microbial killing
-
Mylonas KJ, Nair MG, Prieto-Lafuente L, Paape D, Allen JE. Alternatively activated macrophages elicited by helminth infection can be reprogrammed to enable microbial killing. J Immunol (2009) 182(5):3084-94. doi:10.4049/jimmunol.0803463
-
(2009)
J Immunol
, vol.182
, Issue.5
, pp. 3084-3094
-
-
Mylonas, K.J.1
Nair, M.G.2
Prieto-Lafuente, L.3
Paape, D.4
Allen, J.E.5
-
114
-
-
21244443731
-
Macrophages sequentially change their functional phenotype in response to changes in microenvironmental influences
-
Stout RD, Jiang C, Matta B, Tietzel I, Watkins SK, Suttles J. Macrophages sequentially change their functional phenotype in response to changes in microenvironmental influences. J Immunol (2005) 175(1):342-9. doi:10.4049/jimmunol.175.1.342
-
(2005)
J Immunol
, vol.175
, Issue.1
, pp. 342-349
-
-
Stout, R.D.1
Jiang, C.2
Matta, B.3
Tietzel, I.4
Watkins, S.K.5
Suttles, J.6
-
115
-
-
84877814354
-
Arctigenin ameliorates inflammation in vitro and in vivo by inhibiting the PI3K/AKT pathway and polarizing M1 macrophages to M2-like macrophages
-
Hyam SR, Lee IA, Gu W, Kim KA, Jeong JJ, Jang SE, et al. Arctigenin ameliorates inflammation in vitro and in vivo by inhibiting the PI3K/AKT pathway and polarizing M1 macrophages to M2-like macrophages. Eur J Pharmacol (2013) 708(1-3):21-9. doi:10.1016/j.ejphar.2013.01.014
-
(2013)
Eur J Pharmacol
, vol.708
, Issue.1-3
, pp. 21-29
-
-
Hyam, S.R.1
Lee, I.A.2
Gu, W.3
Kim, K.A.4
Jeong, J.J.5
Jang, S.E.6
-
116
-
-
84881669795
-
Lactobacillus brevis G-101 ameliorates colitis in mice by inhibiting NF-kappaB, MAPK and AKT pathways and by polarizing M1 macrophages to M2-like macrophages
-
Jang SE, Hyam SR, Han MJ, Kim SY, Lee BG, Kim DH. Lactobacillus brevis G-101 ameliorates colitis in mice by inhibiting NF-kappaB, MAPK and AKT pathways and by polarizing M1 macrophages to M2-like macrophages. J Appl Microbiol (2013) 115(3):888-96. doi:10.1111/jam.12273
-
(2013)
J Appl Microbiol
, vol.115
, Issue.3
, pp. 888-896
-
-
Jang, S.E.1
Hyam, S.R.2
Han, M.J.3
Kim, S.Y.4
Lee, B.G.5
Kim, D.H.6
|