-
1
-
-
58249088751
-
MicroRNAs: target recognition and regulatory functions
-
Bartel D.P. MicroRNAs: target recognition and regulatory functions. Cell 2009, 136:215-233.
-
(2009)
Cell
, vol.136
, pp. 215-233
-
-
Bartel, D.P.1
-
2
-
-
84858590826
-
Accessories to the crime: functions of cells recruited to the tumor microenvironment
-
Hanahan D., Coussens L.M. Accessories to the crime: functions of cells recruited to the tumor microenvironment. Cancer Cell 2012, 21:309-322.
-
(2012)
Cancer Cell
, vol.21
, pp. 309-322
-
-
Hanahan, D.1
Coussens, L.M.2
-
3
-
-
45549103746
-
MicroRNAs and the immune response
-
Lindsay M.A. microRNAs and the immune response. Trends Immunol. 2008, 29:343-351.
-
(2008)
Trends Immunol.
, vol.29
, pp. 343-351
-
-
Lindsay, M.A.1
-
4
-
-
84871528926
-
MicroRNAs reprogram normal fibroblasts into cancer-associated fibroblasts in ovarian cancer
-
Mitra A.K., et al. MicroRNAs reprogram normal fibroblasts into cancer-associated fibroblasts in ovarian cancer. Cancer Discov. 2012, 2:1100-1108.
-
(2012)
Cancer Discov.
, vol.2
, pp. 1100-1108
-
-
Mitra, A.K.1
-
5
-
-
84859382730
-
MicroRNA regulation of inflammatory responses
-
O'Connell R.M., et al. microRNA regulation of inflammatory responses. Annu. Rev. Immunol. 2012, 30:295-312.
-
(2012)
Annu. Rev. Immunol.
, vol.30
, pp. 295-312
-
-
O'Connell, R.M.1
-
6
-
-
34248172324
-
Altered macrophage differentiation and immune dysfunction in tumor development
-
Sica A., Bronte V. Altered macrophage differentiation and immune dysfunction in tumor development. J. Clin. Invest. 2007, 117:1155-1166.
-
(2007)
J. Clin. Invest.
, vol.117
, pp. 1155-1166
-
-
Sica, A.1
Bronte, V.2
-
7
-
-
77950950894
-
Macrophage diversity enhances tumor progression and metastasis
-
Qian B.Z., Pollard J.W. Macrophage diversity enhances tumor progression and metastasis. Cell 2010, 141:39-51.
-
(2010)
Cell
, vol.141
, pp. 39-51
-
-
Qian, B.Z.1
Pollard, J.W.2
-
8
-
-
84857692141
-
Differential macrophage programming in the tumor microenvironment
-
Ruffell B., et al. Differential macrophage programming in the tumor microenvironment. Trends Immunol. 2012, 33:119-126.
-
(2012)
Trends Immunol.
, vol.33
, pp. 119-126
-
-
Ruffell, B.1
-
9
-
-
79957923609
-
Macrophage regulation of tumor angiogenesis: implications for cancer therapy
-
Squadrito M.L., De Palma M. Macrophage regulation of tumor angiogenesis: implications for cancer therapy. Mol. Aspects Med. 2011, 32:123-145.
-
(2011)
Mol. Aspects Med.
, vol.32
, pp. 123-145
-
-
Squadrito, M.L.1
De Palma, M.2
-
10
-
-
84863151366
-
Origins of tumor-associated macrophages and neutrophils
-
Cortez-Retamozo V., et al. Origins of tumor-associated macrophages and neutrophils. Proc. Natl. Acad. Sci. U.S.A. 2012, 109:2491-2496.
-
(2012)
Proc. Natl. Acad. Sci. U.S.A.
, vol.109
, pp. 2491-2496
-
-
Cortez-Retamozo, V.1
-
11
-
-
84866920497
-
Immune tolerance to tumor antigens occurs in a specialized environment of the spleen
-
Ugel S., et al. Immune tolerance to tumor antigens occurs in a specialized environment of the spleen. Cell Rep. 2012, 2:628-639.
-
(2012)
Cell Rep.
, vol.2
, pp. 628-639
-
-
Ugel, S.1
-
12
-
-
47049126742
-
Chemokine-mediated rapid turnover of myeloid-derived suppressor cells in tumor-bearing mice
-
Sawanobori Y., et al. Chemokine-mediated rapid turnover of myeloid-derived suppressor cells in tumor-bearing mice. Blood 2008, 111:5457-5466.
-
(2008)
Blood
, vol.111
, pp. 5457-5466
-
-
Sawanobori, Y.1
-
13
-
-
84866022720
-
Regulation of macrophage and dendritic cell responses by their lineage precursors
-
Cortez-Retamozo V., et al. Regulation of macrophage and dendritic cell responses by their lineage precursors. J. Innate Immun. 2012, 4:411-423.
-
(2012)
J. Innate Immun.
, vol.4
, pp. 411-423
-
-
Cortez-Retamozo, V.1
-
14
-
-
77956270732
-
MicroRNA miR-125a controls hematopoietic stem cell number
-
Guo S., et al. MicroRNA miR-125a controls hematopoietic stem cell number. Proc. Natl. Acad. Sci. U.S.A. 2010, 107:14229-14234.
-
(2010)
Proc. Natl. Acad. Sci. U.S.A.
, vol.107
, pp. 14229-14234
-
-
Guo, S.1
-
15
-
-
84870894496
-
Attenuation of miR-126 activity expands HSC in vivo without exhaustion
-
Lechman E.R., et al. Attenuation of miR-126 activity expands HSC in vivo without exhaustion. Cell Stem Cell 2012, 11:799-811.
-
(2012)
Cell Stem Cell
, vol.11
, pp. 799-811
-
-
Lechman, E.R.1
-
16
-
-
80052149793
-
Macrophage development from HSCs requires PU.1-coordinated microRNA expression
-
Ghani S., et al. Macrophage development from HSCs requires PU.1-coordinated microRNA expression. Blood 2011, 118:2275-2284.
-
(2011)
Blood
, vol.118
, pp. 2275-2284
-
-
Ghani, S.1
-
17
-
-
77954488963
-
MiR-146a is differentially expressed by myeloid dendritic cell subsets and desensitizes cells to TLR2-dependent activation
-
Jurkin J., et al. miR-146a is differentially expressed by myeloid dendritic cell subsets and desensitizes cells to TLR2-dependent activation. J. Immunol. 2010, 184:4955-4965.
-
(2010)
J. Immunol.
, vol.184
, pp. 4955-4965
-
-
Jurkin, J.1
-
18
-
-
66549105485
-
Gfi1 regulates miR-21 and miR-196b to control myelopoiesis
-
Velu C.S., et al. Gfi1 regulates miR-21 and miR-196b to control myelopoiesis. Blood 2009, 113:4720-4728.
-
(2009)
Blood
, vol.113
, pp. 4720-4728
-
-
Velu, C.S.1
-
19
-
-
35748979703
-
Epigenetic silencing of the myelopoiesis regulator microRNA-223 by the AML1/ETO oncoprotein
-
Fazi F., et al. Epigenetic silencing of the myelopoiesis regulator microRNA-223 by the AML1/ETO oncoprotein. Cancer Cell 2007, 12:457-466.
-
(2007)
Cancer Cell
, vol.12
, pp. 457-466
-
-
Fazi, F.1
-
20
-
-
70349242211
-
NFI-A directs the fate of hematopoietic progenitors to the erythroid or granulocytic lineage and controls beta-globin and G-CSF receptor expression
-
Starnes L.M., et al. NFI-A directs the fate of hematopoietic progenitors to the erythroid or granulocytic lineage and controls beta-globin and G-CSF receptor expression. Blood 2009, 114:1753-1763.
-
(2009)
Blood
, vol.114
, pp. 1753-1763
-
-
Starnes, L.M.1
-
21
-
-
47149093377
-
The MADS transcription factor Mef2c is a pivotal modulator of myeloid cell fate
-
Schuler A., et al. The MADS transcription factor Mef2c is a pivotal modulator of myeloid cell fate. Blood 2008, 111:4532-4541.
-
(2008)
Blood
, vol.111
, pp. 4532-4541
-
-
Schuler, A.1
-
22
-
-
34347383305
-
MicroRNAs 17-5p-20a-106a control monocytopoiesis through AML1 targeting and M-CSF receptor upregulation
-
Fontana L., et al. MicroRNAs 17-5p-20a-106a control monocytopoiesis through AML1 targeting and M-CSF receptor upregulation. Nat. Cell Biol. 2007, 9:775-787.
-
(2007)
Nat. Cell Biol.
, vol.9
, pp. 775-787
-
-
Fontana, L.1
-
23
-
-
80455164567
-
Epigenetic silencing of the oncogenic miR-17-92 cluster during PU.1-directed macrophage differentiation
-
Pospisil V., et al. Epigenetic silencing of the oncogenic miR-17-92 cluster during PU.1-directed macrophage differentiation. EMBO J. 2011, 30:4450-4464.
-
(2011)
EMBO J.
, vol.30
, pp. 4450-4464
-
-
Pospisil, V.1
-
24
-
-
38049146022
-
The interplay between the master transcription factor PU.1 and miR-424 regulates human monocyte/macrophage differentiation
-
Rosa A., et al. The interplay between the master transcription factor PU.1 and miR-424 regulates human monocyte/macrophage differentiation. Proc. Natl. Acad. Sci. U.S.A. 2007, 104:19849-19854.
-
(2007)
Proc. Natl. Acad. Sci. U.S.A.
, vol.104
, pp. 19849-19854
-
-
Rosa, A.1
-
25
-
-
36549033197
-
The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions
-
Nahrendorf M., et al. The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions. J. Exp. Med. 2007, 204:3037-3047.
-
(2007)
J. Exp. Med.
, vol.204
, pp. 3037-3047
-
-
Nahrendorf, M.1
-
26
-
-
84861148197
-
Regulation of monocyte functional heterogeneity by miR-146a and Relb
-
Etzrodt M., et al. Regulation of monocyte functional heterogeneity by miR-146a and Relb. Cell Rep. 2012, 1:317-324.
-
(2012)
Cell Rep.
, vol.1
, pp. 317-324
-
-
Etzrodt, M.1
-
27
-
-
79959362128
-
NF-kappaB dysregulation in microRNA-146a-deficient mice drives the development of myeloid malignancies
-
Zhao J.L., et al. NF-kappaB dysregulation in microRNA-146a-deficient mice drives the development of myeloid malignancies. Proc. Natl. Acad. Sci. U.S.A. 2011, 108:9184-9189.
-
(2011)
Proc. Natl. Acad. Sci. U.S.A.
, vol.108
, pp. 9184-9189
-
-
Zhao, J.L.1
-
28
-
-
84874227016
-
Angiotensin II drives the production of tumor-promoting macrophages
-
Cortez-Retamozo V., et al. Angiotensin II drives the production of tumor-promoting macrophages. Immunity 2013, 38:296-308.
-
(2013)
Immunity
, vol.38
, pp. 296-308
-
-
Cortez-Retamozo, V.1
-
29
-
-
60849084449
-
Polymorphic mature microRNAs from passenger strand of pre-miR-146a contribute to thyroid cancer
-
Jazdzewski K., et al. Polymorphic mature microRNAs from passenger strand of pre-miR-146a contribute to thyroid cancer. Proc. Natl. Acad. Sci. U.S.A. 2009, 106:1502-1505.
-
(2009)
Proc. Natl. Acad. Sci. U.S.A.
, vol.106
, pp. 1502-1505
-
-
Jazdzewski, K.1
-
30
-
-
77953268611
-
Alternative activation of macrophages: mechanism and functions
-
Gordon S., Martinez F.O. Alternative activation of macrophages: mechanism and functions. Immunity 2010, 32:593-604.
-
(2010)
Immunity
, vol.32
, pp. 593-604
-
-
Gordon, S.1
Martinez, F.O.2
-
31
-
-
84871076444
-
Macrophage plasticity and polarization in tissue repair and remodelling
-
Mantovani A., et al. Macrophage plasticity and polarization in tissue repair and remodelling. J. Pathol. 2013, 229:176-185.
-
(2013)
J. Pathol.
, vol.229
, pp. 176-185
-
-
Mantovani, A.1
-
32
-
-
84857883847
-
Macrophage plasticity and polarization: in vivo veritas
-
Sica A., Mantovani A. Macrophage plasticity and polarization: in vivo veritas. J. Clin. Invest. 2012, 122:787-795.
-
(2012)
J. Clin. Invest.
, vol.122
, pp. 787-795
-
-
Sica, A.1
Mantovani, A.2
-
33
-
-
33847234988
-
A microRNA signature of hypoxia
-
Kulshreshtha R., et al. A microRNA signature of hypoxia. Mol. Cell. Biol. 2007, 27:1859-1867.
-
(2007)
Mol. Cell. Biol.
, vol.27
, pp. 1859-1867
-
-
Kulshreshtha, R.1
-
34
-
-
33846845071
-
MicroRNA-155 is induced during the macrophage inflammatory response
-
O'Connell R.M., et al. MicroRNA-155 is induced during the macrophage inflammatory response. Proc. Natl. Acad. Sci. U.S.A. 2007, 104:1604-1609.
-
(2007)
Proc. Natl. Acad. Sci. U.S.A.
, vol.104
, pp. 1604-1609
-
-
O'Connell, R.M.1
-
35
-
-
78651399501
-
Up-regulation of microRNA-155 in macrophages contributes to increased tumor necrosis factor {alpha} (TNF{alpha}) production via increased mRNA half-life in alcoholic liver disease
-
Bala S., et al. Up-regulation of microRNA-155 in macrophages contributes to increased tumor necrosis factor {alpha} (TNF{alpha}) production via increased mRNA half-life in alcoholic liver disease. J. Biol. Chem. 2011, 286:1436-1444.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 1436-1444
-
-
Bala, S.1
-
36
-
-
73349136775
-
MiR-155: on the crosstalk between inflammation and cancer
-
Tili E., et al. miR-155: on the crosstalk between inflammation and cancer. Int. Rev. Immunol. 2009, 28:264-284.
-
(2009)
Int. Rev. Immunol.
, vol.28
, pp. 264-284
-
-
Tili, E.1
-
37
-
-
68649091506
-
The kinase Akt1 controls macrophage response to lipopolysaccharide by regulating microRNAs
-
Androulidaki A., et al. The kinase Akt1 controls macrophage response to lipopolysaccharide by regulating microRNAs. Immunity 2009, 31:220-231.
-
(2009)
Immunity
, vol.31
, pp. 220-231
-
-
Androulidaki, A.1
-
38
-
-
78650658467
-
Inducible microRNA-155 feedback promotes type I IFN signaling in antiviral innate immunity by targeting suppressor of cytokine signaling 1
-
Wang P., et al. Inducible microRNA-155 feedback promotes type I IFN signaling in antiviral innate immunity by targeting suppressor of cytokine signaling 1. J. Immunol. 2010, 185:6226-6233.
-
(2010)
J. Immunol.
, vol.185
, pp. 6226-6233
-
-
Wang, P.1
-
39
-
-
84868629301
-
MicroRNA-155 promotes atherosclerosis by repressing Bcl6 in macrophages
-
Nazari-Jahantigh M., et al. MicroRNA-155 promotes atherosclerosis by repressing Bcl6 in macrophages. J. Clin. Invest. 2012, 122:4190-4202.
-
(2012)
J. Clin. Invest.
, vol.122
, pp. 4190-4202
-
-
Nazari-Jahantigh, M.1
-
40
-
-
78751483763
-
The interleukin 13 (IL-13) pathway in human macrophages is modulated by microRNA-155 via direct targeting of interleukin 13 receptor alpha1 (IL13Ralpha1)
-
Martinez-Nunez R.T., et al. The interleukin 13 (IL-13) pathway in human macrophages is modulated by microRNA-155 via direct targeting of interleukin 13 receptor alpha1 (IL13Ralpha1). J. Biol. Chem. 2011, 286:1786-1794.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 1786-1794
-
-
Martinez-Nunez, R.T.1
-
41
-
-
84867420120
-
Re-polarization of tumor-associated macrophages to pro-inflammatory M1 macrophages by microRNA-155
-
Cai X., et al. Re-polarization of tumor-associated macrophages to pro-inflammatory M1 macrophages by microRNA-155. J. Mol. Cell Biol. 2012, 4:341-343.
-
(2012)
J. Mol. Cell Biol.
, vol.4
, pp. 341-343
-
-
Cai, X.1
-
42
-
-
70350759666
-
MicroRNA-155 regulates inflammatory cytokine production in tumor-associated macrophages via targeting C/EBPbeta
-
He M., et al. MicroRNA-155 regulates inflammatory cytokine production in tumor-associated macrophages via targeting C/EBPbeta. Cell. Mol. Immunol. 2009, 6:343-352.
-
(2009)
Cell. Mol. Immunol.
, vol.6
, pp. 343-352
-
-
He, M.1
-
43
-
-
84871694595
-
Epistasis between microRNAs 155 and 146a during T cell-mediated antitumor immunity
-
Huffaker T.B., et al. Epistasis between microRNAs 155 and 146a during T cell-mediated antitumor immunity. Cell Rep. 2012, 2:1697-1709.
-
(2012)
Cell Rep.
, vol.2
, pp. 1697-1709
-
-
Huffaker, T.B.1
-
44
-
-
62449173209
-
MicroRNA-155 modulates the interleukin-1 signaling pathway in activated human monocyte-derived dendritic cells
-
Ceppi M., et al. MicroRNA-155 modulates the interleukin-1 signaling pathway in activated human monocyte-derived dendritic cells. Proc. Natl. Acad. Sci. U.S.A. 2009, 106:2735-2740.
-
(2009)
Proc. Natl. Acad. Sci. U.S.A.
, vol.106
, pp. 2735-2740
-
-
Ceppi, M.1
-
45
-
-
77951294330
-
Identification of MyD88 as a novel target of miR-155, involved in negative regulation of Helicobacter pylori-induced inflammation
-
Tang B., et al. Identification of MyD88 as a novel target of miR-155, involved in negative regulation of Helicobacter pylori-induced inflammation. FEBS Lett. 2010, 584:1481-1486.
-
(2010)
FEBS Lett.
, vol.584
, pp. 1481-1486
-
-
Tang, B.1
-
46
-
-
78650668809
-
MiR-155 and its star-form partner miR-155* cooperatively regulate type I interferon production by human plasmacytoid dendritic cells
-
Zhou H., et al. miR-155 and its star-form partner miR-155* cooperatively regulate type I interferon production by human plasmacytoid dendritic cells. Blood 2010, 116:5885-5894.
-
(2010)
Blood
, vol.116
, pp. 5885-5894
-
-
Zhou, H.1
-
47
-
-
66349137358
-
Inositol phosphatase SHIP1 is a primary target of miR-155
-
O'Connell R.M., et al. Inositol phosphatase SHIP1 is a primary target of miR-155. Proc. Natl. Acad. Sci. U.S.A. 2009, 106:7113-7118.
-
(2009)
Proc. Natl. Acad. Sci. U.S.A.
, vol.106
, pp. 7113-7118
-
-
O'Connell, R.M.1
-
48
-
-
84862697885
-
Identifying functional microRNAs in macrophages with polarized phenotypes
-
Graff J.W., et al. Identifying functional microRNAs in macrophages with polarized phenotypes. J. Biol. Chem. 2012, 287:21816-21825.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 21816-21825
-
-
Graff, J.W.1
-
49
-
-
38049030287
-
Modulation of miR-155 and miR-125b levels following lipopolysaccharide/TNF-alpha stimulation and their possible roles in regulating the response to endotoxin shock
-
Tili E., et al. Modulation of miR-155 and miR-125b levels following lipopolysaccharide/TNF-alpha stimulation and their possible roles in regulating the response to endotoxin shock. J. Immunol. 2007, 179:5082-5089.
-
(2007)
J. Immunol.
, vol.179
, pp. 5082-5089
-
-
Tili, E.1
-
50
-
-
84861206450
-
MicroRNAs miR-125a and miR-125b constitutively activate the NF-kappaB pathway by targeting the tumor necrosis factor alpha-induced protein 3 (TNFAIP3, A20)
-
Kim S.W., et al. MicroRNAs miR-125a and miR-125b constitutively activate the NF-kappaB pathway by targeting the tumor necrosis factor alpha-induced protein 3 (TNFAIP3, A20). Proc. Natl. Acad. Sci. U.S.A. 2012, 109:7865-7870.
-
(2012)
Proc. Natl. Acad. Sci. U.S.A.
, vol.109
, pp. 7865-7870
-
-
Kim, S.W.1
-
51
-
-
81455141958
-
MicroRNA-125b potentiates macrophage activation
-
Chaudhuri A.A., et al. MicroRNA-125b potentiates macrophage activation. J. Immunol. 2011, 187:5062-5068.
-
(2011)
J. Immunol.
, vol.187
, pp. 5062-5068
-
-
Chaudhuri, A.A.1
-
52
-
-
33747608638
-
NF-kappaB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses
-
Taganov K.D., et al. NF-kappaB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses. Proc. Natl. Acad. Sci. U.S.A. 2006, 103:12481-12486.
-
(2006)
Proc. Natl. Acad. Sci. U.S.A.
, vol.103
, pp. 12481-12486
-
-
Taganov, K.D.1
-
53
-
-
79958257077
-
MiR-146a is a significant brake on autoimmunity, myeloproliferation, and cancer in mice
-
Boldin M.P., et al. miR-146a is a significant brake on autoimmunity, myeloproliferation, and cancer in mice. J. Exp. Med. 2011, 208:1189-1201.
-
(2011)
J. Exp. Med.
, vol.208
, pp. 1189-1201
-
-
Boldin, M.P.1
-
54
-
-
65249131826
-
Induction and regulatory function of miR-9 in human monocytes and neutrophils exposed to proinflammatory signals
-
Bazzoni F., et al. Induction and regulatory function of miR-9 in human monocytes and neutrophils exposed to proinflammatory signals. Proc. Natl. Acad. Sci. U.S.A. 2009, 106:5282-5287.
-
(2009)
Proc. Natl. Acad. Sci. U.S.A.
, vol.106
, pp. 5282-5287
-
-
Bazzoni, F.1
-
55
-
-
75649113377
-
Negative regulation of TLR4 via targeting of the proinflammatory tumor suppressor PDCD4 by the microRNA miR-21
-
Sheedy F.J., et al. Negative regulation of TLR4 via targeting of the proinflammatory tumor suppressor PDCD4 by the microRNA miR-21. Nat. Immunol. 2010, 11:141-147.
-
(2010)
Nat. Immunol.
, vol.11
, pp. 141-147
-
-
Sheedy, F.J.1
-
56
-
-
70349439320
-
MiR-147, a microRNA that is induced upon Toll-like receptor stimulation, regulates murine macrophage inflammatory responses
-
Liu G., et al. miR-147, a microRNA that is induced upon Toll-like receptor stimulation, regulates murine macrophage inflammatory responses. Proc. Natl. Acad. Sci. U.S.A. 2009, 106:15819-15824.
-
(2009)
Proc. Natl. Acad. Sci. U.S.A.
, vol.106
, pp. 15819-15824
-
-
Liu, G.1
-
57
-
-
33845752914
-
P50 nuclear factor-kappaB overexpression in tumor-associated macrophages inhibits M1 inflammatory responses and antitumor resistance
-
Saccani A., et al. p50 nuclear factor-kappaB overexpression in tumor-associated macrophages inhibits M1 inflammatory responses and antitumor resistance. Cancer Res. 2006, 66:11432-11440.
-
(2006)
Cancer Res.
, vol.66
, pp. 11432-11440
-
-
Saccani, A.1
-
58
-
-
41749113108
-
MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer
-
Asangani I.A., et al. MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer. Oncogene 2008, 27:2128-2136.
-
(2008)
Oncogene
, vol.27
, pp. 2128-2136
-
-
Asangani, I.A.1
-
59
-
-
77956976681
-
Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm
-
Biswas S.K., Mantovani A. Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm. Nat. Immunol. 2010, 11:889-896.
-
(2010)
Nat. Immunol.
, vol.11
, pp. 889-896
-
-
Biswas, S.K.1
Mantovani, A.2
-
60
-
-
84862150859
-
A novel regulator of macrophage activation: miR-223 in obesity-associated adipose tissue inflammation
-
Zhuang G., et al. A novel regulator of macrophage activation: miR-223 in obesity-associated adipose tissue inflammation. Circulation 2012, 125:2892-2903.
-
(2012)
Circulation
, vol.125
, pp. 2892-2903
-
-
Zhuang, G.1
-
61
-
-
84868568561
-
IL-10-induced microRNA-187 negatively regulates TNF-alpha, IL-6, and IL-12p40 production in TLR4-stimulated monocytes
-
Rossato M., et al. IL-10-induced microRNA-187 negatively regulates TNF-alpha, IL-6, and IL-12p40 production in TLR4-stimulated monocytes. Proc. Natl. Acad. Sci. U.S.A. 2012, 109:E3101-E3110.
-
(2012)
Proc. Natl. Acad. Sci. U.S.A.
, vol.109
-
-
Rossato, M.1
-
62
-
-
84866392767
-
Induction of IL-4Ralpha-dependent microRNAs identifies PI3K/Akt signaling as essential for IL-4-driven murine macrophage proliferation in vivo
-
Ruckerl D., et al. Induction of IL-4Ralpha-dependent microRNAs identifies PI3K/Akt signaling as essential for IL-4-driven murine macrophage proliferation in vivo. Blood 2012, 120:2307-2316.
-
(2012)
Blood
, vol.120
, pp. 2307-2316
-
-
Ruckerl, D.1
-
63
-
-
84861152312
-
MiR-511-3p modulates genetic programs of tumor-associated macrophages
-
Squadrito M.L., et al. miR-511-3p modulates genetic programs of tumor-associated macrophages. Cell Rep. 2012, 1:141-154.
-
(2012)
Cell Rep.
, vol.1
, pp. 141-154
-
-
Squadrito, M.L.1
-
65
-
-
79960691435
-
MicroRNA expression profiles of human blood monocyte-derived dendritic cells and macrophages reveal miR-511 as putative positive regulator of Toll-like receptor 4
-
Tserel L., et al. MicroRNA expression profiles of human blood monocyte-derived dendritic cells and macrophages reveal miR-511 as putative positive regulator of Toll-like receptor 4. J. Biol. Chem. 2011, 286:26487-26495.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 26487-26495
-
-
Tserel, L.1
-
66
-
-
84878802380
-
Comprehensive analysis of microRNAs in breast cancer
-
Chang H.T., et al. Comprehensive analysis of microRNAs in breast cancer. BMC Genomics 2012, 13:S18.
-
(2012)
BMC Genomics
, vol.13
-
-
Chang, H.T.1
-
67
-
-
84862908547
-
Mechanism of transfer of functional microRNAs between mouse dendritic cells via exosomes
-
Montecalvo A., et al. Mechanism of transfer of functional microRNAs between mouse dendritic cells via exosomes. Blood 2012, 119:756-766.
-
(2012)
Blood
, vol.119
, pp. 756-766
-
-
Montecalvo, A.1
-
68
-
-
80053175966
-
Microvesicles secreted by macrophages shuttle invasion-potentiating microRNAs into breast cancer cells
-
Yang M., et al. Microvesicles secreted by macrophages shuttle invasion-potentiating microRNAs into breast cancer cells. Mol. Cancer 2011, 10:117.
-
(2011)
Mol. Cancer
, vol.10
, pp. 117
-
-
Yang, M.1
-
69
-
-
84864503916
-
MicroRNAs bind to Toll-like receptors to induce prometastatic inflammatory response
-
Fabbri M., et al. MicroRNAs bind to Toll-like receptors to induce prometastatic inflammatory response. Proc. Natl. Acad. Sci. U.S.A. 2012, 109:E2110-E2116.
-
(2012)
Proc. Natl. Acad. Sci. U.S.A.
, vol.109
-
-
Fabbri, M.1
-
70
-
-
84878023280
-
Molecular pathways: tumor-derived microvesicles and their interactions with immune cells in vivo
-
Pucci F., Pittet M.J. Molecular pathways: tumor-derived microvesicles and their interactions with immune cells in vivo. Clin. Cancer Res 2013, 10.1158/1078-0432.CCR-12-0962.
-
(2013)
Clin. Cancer Res
-
-
Pucci, F.1
Pittet, M.J.2
-
71
-
-
34247593034
-
Impaired microRNA processing enhances cellular transformation and tumorigenesis
-
Kumar M.S., et al. Impaired microRNA processing enhances cellular transformation and tumorigenesis. Nat. Genet. 2007, 39:673-677.
-
(2007)
Nat. Genet.
, vol.39
, pp. 673-677
-
-
Kumar, M.S.1
-
72
-
-
67651087321
-
Exploiting and antagonizing microRNA regulation for therapeutic and experimental applications
-
Brown B.D., Naldini L. Exploiting and antagonizing microRNA regulation for therapeutic and experimental applications. Nat. Rev. Genet. 2009, 10:578-585.
-
(2009)
Nat. Rev. Genet.
, vol.10
, pp. 578-585
-
-
Brown, B.D.1
Naldini, L.2
-
73
-
-
84859386994
-
Reprogramming tumor-associated dendritic cells in vivo using miRNA mimetics triggers protective immunity against ovarian cancer
-
Cubillos-Ruiz J.R., et al. Reprogramming tumor-associated dendritic cells in vivo using miRNA mimetics triggers protective immunity against ovarian cancer. Cancer Res. 2012, 72:1683-1693.
-
(2012)
Cancer Res.
, vol.72
, pp. 1683-1693
-
-
Cubillos-Ruiz, J.R.1
-
74
-
-
77956901498
-
The promise of microRNA replacement therapy
-
Bader A.G., et al. The promise of microRNA replacement therapy. Cancer Res. 2010, 70:7027-7030.
-
(2010)
Cancer Res.
, vol.70
, pp. 7027-7030
-
-
Bader, A.G.1
-
75
-
-
42249093319
-
LNA-mediated microRNA silencing in non-human primates
-
Elmen J., et al. LNA-mediated microRNA silencing in non-human primates. Nature 2008, 452:896-899.
-
(2008)
Nature
, vol.452
, pp. 896-899
-
-
Elmen, J.1
-
76
-
-
74249112787
-
Therapeutic silencing of microRNA-122 in primates with chronic hepatitis C virus infection
-
Lanford R.E., et al. Therapeutic silencing of microRNA-122 in primates with chronic hepatitis C virus infection. Science 2010, 327:198-201.
-
(2010)
Science
, vol.327
, pp. 198-201
-
-
Lanford, R.E.1
-
77
-
-
49949116902
-
The impact of microRNAs on protein output
-
Baek D., et al. The impact of microRNAs on protein output. Nature 2008, 455:64-71.
-
(2008)
Nature
, vol.455
, pp. 64-71
-
-
Baek, D.1
-
78
-
-
77955644289
-
Mammalian microRNAs predominantly act to decrease target mRNA levels
-
Guo H., et al. Mammalian microRNAs predominantly act to decrease target mRNA levels. Nature 2010, 466:835-840.
-
(2010)
Nature
, vol.466
, pp. 835-840
-
-
Guo, H.1
-
79
-
-
37749036293
-
Most Caenorhabditis elegans microRNAs are individually not essential for development or viability
-
Miska E.A., et al. Most Caenorhabditis elegans microRNAs are individually not essential for development or viability. PLoS Genet. 2007, 3:e215.
-
(2007)
PLoS Genet.
, vol.3
-
-
Miska, E.A.1
-
80
-
-
84861116472
-
A resource for the conditional ablation of microRNAs in the mouse
-
Park C.Y., et al. A resource for the conditional ablation of microRNAs in the mouse. Cell Rep. 2012, 1:385-391.
-
(2012)
Cell Rep.
, vol.1
, pp. 385-391
-
-
Park, C.Y.1
-
81
-
-
84864448111
-
High-throughput assessment of microRNA activity and function using microRNA sensor and decoy libraries
-
Mullokandov G., et al. High-throughput assessment of microRNA activity and function using microRNA sensor and decoy libraries. Nat. Methods 2012, 9:840-846.
-
(2012)
Nat. Methods
, vol.9
, pp. 840-846
-
-
Mullokandov, G.1
-
82
-
-
34250805982
-
MicroRNA targeting specificity in mammals: determinants beyond seed pairing
-
Grimson A., et al. MicroRNA targeting specificity in mammals: determinants beyond seed pairing. Mol. Cell 2007, 27:91-105.
-
(2007)
Mol. Cell
, vol.27
, pp. 91-105
-
-
Grimson, A.1
-
83
-
-
84858446579
-
MicroRNAs and their targets: recognition, regulation and an emerging reciprocal relationship
-
Pasquinelli A.E. MicroRNAs and their targets: recognition, regulation and an emerging reciprocal relationship. Nat. Rev. Genet. 2012, 13:271-282.
-
(2012)
Nat. Rev. Genet.
, vol.13
, pp. 271-282
-
-
Pasquinelli, A.E.1
-
84
-
-
70349320158
-
Causes and consequences of microRNA dysregulation in cancer
-
Croce C.M. Causes and consequences of microRNA dysregulation in cancer. Nat. Rev. Genet. 2009, 10:704-714.
-
(2009)
Nat. Rev. Genet.
, vol.10
, pp. 704-714
-
-
Croce, C.M.1
-
85
-
-
81855224576
-
Epigenetics and genetics. MicroRNAs en route to the clinic: progress in validating and targeting microRNAs for cancer therapy
-
Kasinski A.L., Slack F.J. Epigenetics and genetics. MicroRNAs en route to the clinic: progress in validating and targeting microRNAs for cancer therapy. Nat. Rev. Cancer 2011, 11:849-864.
-
(2011)
Nat. Rev. Cancer
, vol.11
, pp. 849-864
-
-
Kasinski, A.L.1
Slack, F.J.2
-
86
-
-
18744396337
-
Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia
-
Calin G.A., et al. Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia. Proc. Natl. Acad. Sci. U.S.A. 2002, 99:15524-15529.
-
(2002)
Proc. Natl. Acad. Sci. U.S.A.
, vol.99
, pp. 15524-15529
-
-
Calin, G.A.1
-
87
-
-
77952918274
-
Genetic variation in microRNA networks: the implications for cancer research
-
Ryan B.M., et al. Genetic variation in microRNA networks: the implications for cancer research. Nat. Rev. Cancer 2010, 10:389-402.
-
(2010)
Nat. Rev. Cancer
, vol.10
, pp. 389-402
-
-
Ryan, B.M.1
-
88
-
-
7644231561
-
The chemokine system in diverse forms of macrophage activation and polarization
-
Mantovani A., et al. The chemokine system in diverse forms of macrophage activation and polarization. Trends Immunol. 2004, 25:677-686.
-
(2004)
Trends Immunol.
, vol.25
, pp. 677-686
-
-
Mantovani, A.1
-
89
-
-
84862187485
-
Akt1 and Akt2 protein kinases differentially contribute to macrophage polarization
-
Arranz A., et al. Akt1 and Akt2 protein kinases differentially contribute to macrophage polarization. Proc. Natl. Acad. Sci. U.S.A. 2012, 109:9517-9522.
-
(2012)
Proc. Natl. Acad. Sci. U.S.A.
, vol.109
, pp. 9517-9522
-
-
Arranz, A.1
-
90
-
-
80355146399
-
Transcriptional regulation of macrophage polarization: enabling diversity with identity
-
Lawrence T., Natoli G. Transcriptional regulation of macrophage polarization: enabling diversity with identity. Nat. Rev. Immunol. 2011, 11:750-761.
-
(2011)
Nat. Rev. Immunol.
, vol.11
, pp. 750-761
-
-
Lawrence, T.1
Natoli, G.2
-
91
-
-
67650485985
-
Alternative activation of macrophages: an immunologic functional perspective
-
Martinez F.O., et al. Alternative activation of macrophages: an immunologic functional perspective. Annu. Rev. Immunol. 2009, 27:451-483.
-
(2009)
Annu. Rev. Immunol.
, vol.27
, pp. 451-483
-
-
Martinez, F.O.1
-
92
-
-
33344460032
-
A distinct and unique transcriptional program expressed by tumor-associated macrophages (defective NF-kappaB and enhanced IRF-3/STAT1 activation)
-
Biswas S.K., et al. A distinct and unique transcriptional program expressed by tumor-associated macrophages (defective NF-kappaB and enhanced IRF-3/STAT1 activation). Blood 2006, 107:2112-2122.
-
(2006)
Blood
, vol.107
, pp. 2112-2122
-
-
Biswas, S.K.1
-
93
-
-
67651111095
-
A distinguishing gene signature shared by tumor-infiltrating Tie2-expressing monocytes, blood "resident" monocytes, and embryonic macrophages suggests common functions and developmental relationships
-
Pucci F., et al. A distinguishing gene signature shared by tumor-infiltrating Tie2-expressing monocytes, blood "resident" monocytes, and embryonic macrophages suggests common functions and developmental relationships. Blood 2009, 114:901-914.
-
(2009)
Blood
, vol.114
, pp. 901-914
-
-
Pucci, F.1
-
94
-
-
0037199972
-
The phosphatidylinositol 3-kinase-Akt pathway limits lipopolysaccharide activation of signaling pathways and expression of inflammatory mediators in human monocytic cells
-
Guha M., Mackman N. The phosphatidylinositol 3-kinase-Akt pathway limits lipopolysaccharide activation of signaling pathways and expression of inflammatory mediators in human monocytic cells. J. Biol. Chem. 2002, 277:32124-32132.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 32124-32132
-
-
Guha, M.1
Mackman, N.2
-
95
-
-
45149134605
-
"Re-educating" tumor-associated macrophages by targeting NF-kappaB
-
Hagemann T., et al. "Re-educating" tumor-associated macrophages by targeting NF-kappaB. J. Exp. Med. 2008, 205:1261-1268.
-
(2008)
J. Exp. Med.
, vol.205
, pp. 1261-1268
-
-
Hagemann, T.1
-
96
-
-
67651160649
-
CD4(+) T cells regulate pulmonary metastasis of mammary carcinomas by enhancing protumor properties of macrophages
-
DeNardo D.G., et al. CD4(+) T cells regulate pulmonary metastasis of mammary carcinomas by enhancing protumor properties of macrophages. Cancer Cell 2009, 16:91-102.
-
(2009)
Cancer Cell
, vol.16
, pp. 91-102
-
-
DeNardo, D.G.1
-
97
-
-
84867749039
-
Endothelial cells provide an instructive niche for the differentiation and functional polarization of M2-like macrophages
-
He H., et al. Endothelial cells provide an instructive niche for the differentiation and functional polarization of M2-like macrophages. Blood 2012, 120:3152-3162.
-
(2012)
Blood
, vol.120
, pp. 3152-3162
-
-
He, H.1
-
98
-
-
24944587964
-
Tie2 identifies a hematopoietic lineage of proangiogenic monocytes required for tumor vessel formation and a mesenchymal population of pericyte progenitors
-
De Palma M., et al. Tie2 identifies a hematopoietic lineage of proangiogenic monocytes required for tumor vessel formation and a mesenchymal population of pericyte progenitors. Cancer Cell 2005, 8:211-226.
-
(2005)
Cancer Cell
, vol.8
, pp. 211-226
-
-
De Palma, M.1
-
99
-
-
79953750307
-
Targeting the ANG2/TIE2 axis inhibits tumor growth and metastasis by impairing angiogenesis and disabling rebounds of proangiogenic myeloid cells
-
Mazzieri R., et al. Targeting the ANG2/TIE2 axis inhibits tumor growth and metastasis by impairing angiogenesis and disabling rebounds of proangiogenic myeloid cells. Cancer Cell 2011, 19:512-526.
-
(2011)
Cancer Cell
, vol.19
, pp. 512-526
-
-
Mazzieri, R.1
-
100
-
-
77955038532
-
Different tumor microenvironments contain functionally distinct subsets of macrophages derived from Ly6C(high) monocytes
-
Movahedi K., et al. Different tumor microenvironments contain functionally distinct subsets of macrophages derived from Ly6C(high) monocytes. Cancer Res. 2010, 70:5728-5739.
-
(2010)
Cancer Res.
, vol.70
, pp. 5728-5739
-
-
Movahedi, K.1
|