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Volumn 90, Issue 5, 2011, Pages 845-854

Suppressor of cytokine signaling (SOCS)1 is a key determinant of differential macrophage activation and function

Author keywords

Arginase I; Brugia malayi; Inducible nitric oxide synthase; Inflammation; M1 activation; M2 activation

Indexed keywords

ARGINASE; ARGINASE 1; GAMMA INTERFERON; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 4; INTERLEUKIN 6; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; NITRIC OXIDE; PHOSPHATIDYLINOSITOL 3 KINASE; SMALL INTERFERING RNA; SUPPRESSOR OF CYTOKINE SIGNALING 1;

EID: 80055096913     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1189/jlb.1110644     Document Type: Article
Times cited : (167)

References (50)
  • 1
    • 26644452073 scopus 로고    scopus 로고
    • Macrophage polarization comes of age
    • Mantovani, A., Sica, A., Locati, M. (2005) Macrophage polarization comes of age. Immunity 23, 344-346.
    • (2005) Immunity , vol.23 , pp. 344-346
    • Mantovani, A.1    Sica, A.2    Locati, M.3
  • 3
    • 77957108119 scopus 로고    scopus 로고
    • Macrophages heterogeneity in atherosclerosis-implications for therapy
    • Wilson, H. M. (2010) Macrophages heterogeneity in atherosclerosis-implications for therapy. J. Cell. Mol. Med. 14, 2055-2065.
    • (2010) J. Cell. Mol. Med , vol.14 , pp. 2055-2065
    • Wilson, H.M.1
  • 5
    • 77953268611 scopus 로고    scopus 로고
    • Alternative activation of macrophages: Mechanism and function
    • Gordon, S., Martinez, F. O. (2010) Alternative activation of macrophages: mechanism and function. Immunity 32, 593-604.
    • (2010) Immunity , vol.32 , pp. 593-604
    • Gordon, S.1    Martinez, F.O.2
  • 6
    • 56749174940 scopus 로고    scopus 로고
    • Exploring the full spectrum of macrophage activation
    • Mosser, D. M., Edwards, J. P. (2008) Exploring the full spectrum of macrophage activation. Nat. Rev. Immunol. 8, 958-969.
    • (2008) Nat. Rev. Immunol , vol.8 , pp. 958-969
    • Mosser, D.M.1    Edwards, J.P.2
  • 7
    • 70350529527 scopus 로고    scopus 로고
    • Functional plasticity of macrophages: In situ reprogramming of tumor-associated macrophages
    • Stout, R. D., Watkins, S. K., Suttles, J. (2009) Functional plasticity of macrophages: in situ reprogramming of tumor-associated macrophages. J. Leukoc. Biol. 86, 1105-1109.
    • (2009) J. Leukoc. Biol , vol.86 , pp. 1105-1109
    • Stout, R.D.1    Watkins, S.K.2    Suttles, J.3
  • 8
    • 64849097221 scopus 로고    scopus 로고
    • Alternatively activated macrophages elicited by helminth infection can be reprogrammed to enable microbial killing
    • Mylonas, K. J., Nair, M. G., Prieto-Lafuente, L., Paape, D., Allen, J. E. (2009) Alternatively activated macrophages elicited by helminth infection can be reprogrammed to enable microbial killing. J. Immunol. 182, 3084-3094.
    • (2009) J. Immunol , vol.182 , pp. 3084-3094
    • Mylonas, K.J.1    Nair, M.G.2    Prieto-Lafuente, L.3    Paape, D.4    Allen, J.E.5
  • 9
    • 0033884751 scopus 로고    scopus 로고
    • Macrophages from inflamed but not normal glomeruli are unresponsive to anti-inflammatory cytokines
    • Erwig, L. P., Stewart, K. N., Rees, A. J. (2000) Macrophages from inflamed but not normal glomeruli are unresponsive to anti-inflammatory cytokines. Am. J. Pathol. 156, 295-301.
    • (2000) Am. J. Pathol , vol.156 , pp. 295-301
    • Erwig, L.P.1    Stewart, K.N.2    Rees, A.J.3
  • 10
    • 3543107212 scopus 로고    scopus 로고
    • Fibrotic disease and the T(H)1/T(H)2 paradigm
    • Wynn, T. A. (2004) Fibrotic disease and the T(H)1/T(H)2 paradigm. Nat. Rev. Immunol. 4, 583-594.
    • (2004) Nat. Rev. Immunol , vol.4 , pp. 583-594
    • Wynn, T.A.1
  • 11
    • 34249660614 scopus 로고    scopus 로고
    • SOCS proteins, cytokine signaling and immune regulation
    • Yoshimura, A., Naka, T., Kubo, M. (2007) SOCS proteins, cytokine signaling and immune regulation. Nat. Rev. Immunol. 7, 454-465.
    • (2007) Nat. Rev. Immunol , vol.7 , pp. 454-465
    • Yoshimura, A.1    Naka, T.2    Kubo, M.3
  • 12
    • 41649103890 scopus 로고    scopus 로고
    • Regulation of innate immunity by suppressor of cytokine signaling (SOCS) proteins
    • Dalpke, A., Heeg, K., Bartz, H., Baetz, A. (2008) Regulation of innate immunity by suppressor of cytokine signaling (SOCS) proteins. Immunobiology 213, 225-235.
    • (2008) Immunobiology , vol.213 , pp. 225-235
    • Dalpke, A.1    Heeg, K.2    Bartz, H.3    Baetz, A.4
  • 13
    • 24044434247 scopus 로고    scopus 로고
    • The absence of platelet-derived growth factor-B in circulating cells promotes immune and inflammatory responses in atherosclerosis-prone ApoE-/-mice
    • Tang, J., Kozaki, K., Farr, A. G., Martin, P. J., Lindahl, P., Betsholtz, C., Raines, E. W. (2005) The absence of platelet-derived growth factor-B in circulating cells promotes immune and inflammatory responses in atherosclerosis-prone ApoE-/-mice. Am. J. Pathol. 167, 901-912.
    • (2005) Am. J. Pathol , vol.167 , pp. 901-912
    • Tang, J.1    Kozaki, K.2    Farr, A.G.3    Martin, P.J.4    Lindahl, P.5    Betsholtz, C.6    Raines, E.W.7
  • 15
    • 44449140105 scopus 로고    scopus 로고
    • Unique expression of suppressor of cytokine signaling 3 is essential for classical macrophage activation in rodents in vitro and in vivo
    • Liu, Y., Stewart, K. N., Bishop, E. T., Marek, C. M., Kluth, D. C., Rees, A. J., Wilson, H. M. (2008) Unique expression of suppressor of cytokine signaling 3 is essential for classical macrophage activation in rodents in vitro and in vivo. J. Immunol. 180, 6270-6278.
    • (2008) J. Immunol , vol.180 , pp. 6270-6278
    • Liu, Y.1    Stewart, K.N.2    Bishop, E.T.3    Marek, C.M.4    Kluth, D.C.5    Rees, A.J.6    Wilson, H.M.7
  • 22
    • 34249823656 scopus 로고    scopus 로고
    • Type 2 diabetes impairs insulin receptor substrate-2-mediated phosphatidylinositol 3-kinase activity in primary macrophages to induce a state of cytokine resistance to IL-4 in association with overexpression of suppressor of cytokine signaling-3
    • O'Connor, J. C., Sherry, C. L., Guest, C. B., Freund, G. G. (2007) Type 2 diabetes impairs insulin receptor substrate-2-mediated phosphatidylinositol 3-kinase activity in primary macrophages to induce a state of cytokine resistance to IL-4 in association with overexpression of suppressor of cytokine signaling-3. J. Immunol. 178, 6886-6893.
    • (2007) J. Immunol , vol.178 , pp. 6886-6893
    • O'Connor, J.C.1    Sherry, C.L.2    Guest, C.B.3    Freund, G.G.4
  • 25
    • 11144233242 scopus 로고    scopus 로고
    • Suppressor of cytokine signaling (SOCS) proteins indirectly regulate Toll-like receptor signaling in innate immune cells
    • Baetz, A., Frey, M., Heeg, K., Dalpke, A. H. (2004) Suppressor of cytokine signaling (SOCS) proteins indirectly regulate Toll-like receptor signaling in innate immune cells. J. Biol. Chem. 279, 54708-54715.
    • (2004) J. Biol. Chem , vol.279 , pp. 54708-54715
    • Baetz, A.1    Frey, M.2    Heeg, K.3    Dalpke, A.H.4
  • 26
    • 0034106507 scopus 로고    scopus 로고
    • Interleukin-4 receptor α-deficient BALB/c mice show an unimpaired T helper 2 polarization in response to Leishmania major infection
    • Mohrs, M., Holscher, C., Brombacher, F. (2000) Interleukin-4 receptor α-deficient BALB/c mice show an unimpaired T helper 2 polarization in response to Leishmania major infection. Infect. Immun. 68, 1773-1780.
    • (2000) Infect. Immun , vol.68 , pp. 1773-1780
    • Mohrs, M.1    Holscher, C.2    Brombacher, F.3
  • 27
    • 0033825617 scopus 로고    scopus 로고
    • Alternatively activated macrophages induced by nematode infection inhibit proliferation via cell-to-cell contact
    • Loke, P., MacDonald, A. S., Robb, A., Maizels, R. M., Allen, J. E. (2000) Alternatively activated macrophages induced by nematode infection inhibit proliferation via cell-to-cell contact. Eur. J. Immunol. 30, 2669-2678.
    • (2000) Eur. J. Immunol , vol.30 , pp. 2669-2678
    • Loke, P.1    McDonald, A.S.2    Robb, A.3    Maizels, R.M.4    Allen, J.E.5
  • 28
    • 0036941189 scopus 로고    scopus 로고
    • Bone marrow derived macrophages genetically modified to produce IL-10 reduce injury in experimental glomerulonephritis
    • Wilson, H. M., Stewart, K. N., Brown, P. A. J., Anegon, I., Chettibi, S., Rees, A. J., Kluth, D. C. (2002) Bone marrow derived macrophages genetically modified to produce IL-10 reduce injury in experimental glomerulonephritis. Mol. Ther. 6, 710-717.
    • (2002) Mol. Ther , vol.6 , pp. 710-717
    • Wilson, H.M.1    Stewart, K.N.2    Brown, P.A.J.3    Anegon, I.4    Chettibi, S.5    Rees, A.J.6    Kluth, D.C.7
  • 29
    • 11144286421 scopus 로고    scopus 로고
    • Chitinase and Fizz family members are a generalized feature of nematode infection with selective upregulation of Yml and Fizzl by antigen-presenting cells
    • Nair, M. G., Gallagher, I. J., Taylor, M. D., Loke, P., Coulson, P. S., Wilson, R. A., Maizels, R. M., Allen, J. E. (2005) Chitinase and Fizz family members are a generalized feature of nematode infection with selective upregulation of Yml and Fizzl by antigen-presenting cells. Infect. Immun. 73, 385-394.
    • (2005) Infect. Immun , vol.73 , pp. 385-394
    • Nair, M.G.1    Gallagher, I.J.2    Taylor, M.D.3    Loke, P.4    Coulson, P.S.5    Wilson, R.A.6    Maizels, R.M.7    Allen, J.E.8
  • 30
    • 3142694849 scopus 로고    scopus 로고
    • Cell proliferation and STAT6 pathway are negatively regulated in T cells by STAT1 and suppressors of cytokine signaling
    • Yu, C. R., Mahdi, R. M., Ebong, S., Vistica, B. P., Chen, J., Guo, Y., Gery, I., Egwuagu, C. E. (2004) Cell proliferation and STAT6 pathway are negatively regulated in T cells by STAT1 and suppressors of cytokine signaling. J. Immunol. 173, 737-746.
    • (2004) J. Immunol , vol.173 , pp. 737-746
    • Yu, C.R.1    Mahdi, R.M.2    Ebong, S.3    Vistica, B.P.4    Chen, J.5    Guo, Y.6    Gery, I.7    Egwuagu, C.E.8
  • 31
    • 0027934360 scopus 로고
    • Determination of arginase activity in macrophages: A micromethod
    • Corraliza, I. M., Campo, M. L., Soler, G., Modolell, M. (1994) Determination of arginase activity in macrophages: a micromethod. J. Immunol. Methods 174, 231-235.
    • (1994) J. Immunol. Methods , vol.174 , pp. 231-235
    • Corraliza, I.M.1    Campo, M.L.2    Soler, G.3    Modolell, M.4
  • 32
    • 49249132865 scopus 로고    scopus 로고
    • Putting out the fire: Coordinated suppression of the innate and adaptive immune systems by SOCS1 and SOCS3 proteins
    • Dimitriou, I. D., Clemenza, L., Scotter, A. J., Chen, G., Guerra, F. M., Rottapel, R. (2008) Putting out the fire: coordinated suppression of the innate and adaptive immune systems by SOCS1 and SOCS3 proteins. Immunol. Rev. 224, 265-283.
    • (2008) Immunol. Rev , vol.224 , pp. 265-283
    • Dimitriou, I.D.1    Clemenza, L.2    Scotter, A.J.3    Chen, G.4    Guerra, F.M.5    Rottapel, R.6
  • 33
    • 33846523494 scopus 로고    scopus 로고
    • Suppressor of cytokine signaling-1 is an IL-4-inducible gene in macrophages and feedback inhibits IL-4 signaling
    • Dickensheets, H., Vazquez, N., Sheikh, F., Gingras, S., Murray, P. J., Ryan, J. J., Donnelly, R. P. (2007) Suppressor of cytokine signaling-1 is an IL-4-inducible gene in macrophages and feedback inhibits IL-4 signaling. Genes Immun. 8, 21-27.
    • (2007) Genes Immun , vol.8 , pp. 21-27
    • Dickensheets, H.1    Vazquez, N.2    Sheikh, F.3    Gingras, S.4    Murray, P.J.5    Ryan, J.J.6    Donnelly, R.P.7
  • 34
    • 35748964164 scopus 로고    scopus 로고
    • Alternative activation is an innate response to injury that requires CD4+ T cells to be sustained during chronic infection
    • Loke, P., Gallagher, I., Nair, M. G., Zang, X., Brombacher, F., Mohrs, M., Allison, J. P., Allen, J. E. (2007) Alternative activation is an innate response to injury that requires CD4+ T cells to be sustained during chronic infection. J. Immunol. 179, 3926-3936.
    • (2007) J. Immunol , vol.179 , pp. 3926-3936
    • Loke, P.1    Gallagher, I.2    Nair, M.G.3    Zang, X.4    Brombacher, F.5    Mohrs, M.6    Allison, J.P.7    Allen, J.E.8
  • 42
    • 11144224785 scopus 로고    scopus 로고
    • Re-examination of the role of suppressor of cytokine signaling 1 (SOCS1) in the regulation of Toll-like receptor signaling
    • Gingras, S., Parganas, E., de Pauw, A., Ihle, J. N., Murray, P. J. (2004) Re-examination of the role of suppressor of cytokine signaling 1 (SOCS1) in the regulation of Toll-like receptor signaling. J. Biol. Chem. 279, 54702-54707.
    • (2004) J. Biol. Chem , vol.279 , pp. 54702-54707
    • Gingras, S.1    Parganas, E.2    de Pauw, A.3    Ihle, J.N.4    Murray, P.J.5
  • 43
    • 84920506276 scopus 로고    scopus 로고
    • SOCS1 regulates the IFN but not NFκB pathway in TLR-stimulated human monocytes and macrophages
    • Prêle, C. M., Woodward, E. A., Bisley, J., Keith-Magee, A., Nicholson, S. E., Hart, P. H. (2008) SOCS1 regulates the IFN but not NFκB pathway in TLR-stimulated human monocytes and macrophages. J. Immunol. 181, 8018-8026.
    • (2008) J. Immunol , vol.181 , pp. 8018-8026
    • Prêle, C.M.1    Woodward, E.A.2    Bisley, J.3    Keith-Magee, A.4    Nicholson, S.E.5    Hart, P.H.6
  • 44
    • 67650491342 scopus 로고    scopus 로고
    • Alternatively activated and immunoregulatory monocytes in human filarial infections
    • Babu, S., Kumaraswami, V., Nutman, T. B. (2009) Alternatively activated and immunoregulatory monocytes in human filarial infections. J. Infect. Dis. 199, 1827-1837.
    • (2009) J. Infect. Dis , vol.199 , pp. 1827-1837
    • Babu, S.1    Kumaraswami, V.2    Nutman, T.B.3
  • 47
    • 0036533474 scopus 로고    scopus 로고
    • Suppressors of cytokine signaling proteins are differentially expressed in Th1 and Th2 cells: Implications for Th cell lineage commitment and maintenance
    • Egwuagu, C. E., Yu, C. R., Zhang, M., Mahdi, R. M., Kim, S. J., Gery, I. (2002) Suppressors of cytokine signaling proteins are differentially expressed in Th1 and Th2 cells: implications for Th cell lineage commitment and maintenance. J. Immunol. 168, 3181-3187.
    • (2002) J. Immunol , vol.168 , pp. 3181-3187
    • Egwuagu, C.E.1    Yu, C.R.2    Zhang, M.3    Mahdi, R.M.4    Kim, S.J.5    Gery, I.6
  • 48
    • 0035576207 scopus 로고    scopus 로고
    • Differential regulation of nitric oxide synthase-2 and arginase-1 by type 1/type 2 cytokines in vivo: Granulomatous pathology is shaped by the pattern of L-arginine metabolism
    • Hesse, M., Modolell, M., La Flamme, A. C., Schito, M., Fuentes, J. M., Cheever, A. W., Pearce, E. J., Wynn, T. A. (2001) Differential regulation of nitric oxide synthase-2 and arginase-1 by type 1/type 2 cytokines in vivo: granulomatous pathology is shaped by the pattern of L-arginine metabolism. J. Immunol. 167, 6533-6544.
    • (2001) J. Immunol , vol.167 , pp. 6533-6544
    • Hesse, M.1    Modolell, M.2    la Flamme, A.C.3    Schito, M.4    Fuentes, J.M.5    Cheever, A.W.6    Pearce, E.J.7    Wynn, T.A.8
  • 49
    • 21244475215 scopus 로고    scopus 로고
    • Inhibition of macrophage nuclear factor-κ B (NF-κB) leads to a dominant anti-inflammatory phenotype that attenuates glomerular inflammation in vivo
    • Wilson, H. M., Chettibi, S., Jobin, C., Walbaum, D., Rees, A. J., Kluth, D. C. (2005) Inhibition of macrophage nuclear factor-κ B (NF-κB) leads to a dominant anti-inflammatory phenotype that attenuates glomerular inflammation in vivo. Am. J. Pathol. 167, 27-37.
    • (2005) Am. J. Pathol , vol.167 , pp. 27-37
    • Wilson, H.M.1    Chettibi, S.2    Jobin, C.3    Walbaum, D.4    Rees, A.J.5    Kluth, D.C.6
  • 50
    • 11144254962 scopus 로고    scopus 로고
    • Silencing of SOCS1 enhances antigen presentation by dendritic cells and antigen-specific anti-tumor immunity
    • Shen, L., Evel-Kabler, K., Strube, R., Chen, S. Y. (2004) Silencing of SOCS1 enhances antigen presentation by dendritic cells and antigen-specific anti-tumor immunity. Nat. Biotechnol. 22, 1546-1553.
    • (2004) Nat. Biotechnol , vol.22 , pp. 1546-1553
    • Shen, L.1    Evel-Kabler, K.2    Strube, R.3    Chen, S.Y.4


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