-
1
-
-
28544446111
-
Monocyte and macrophage heterogeneity
-
Gordon S, Taylor PR. Monocyte and macrophage heterogeneity. Nat Rev Immunol. 2005;5:953-964.
-
(2005)
Nat Rev Immunol
, vol.5
, pp. 953-964
-
-
Gordon, S.1
Taylor, P.R.2
-
2
-
-
61449195530
-
Resolution-phase macrophages possess a unique inflammatory phenotype that is controlled by cAMP
-
Bystrom J, Evans I, Newson J, Stables M, Toor I, Van RN, Crawford M, Colville-Nash P, Farrow S, Gilroy DW. Resolution-phase macrophages possess a unique inflammatory phenotype that is controlled by cAMP. Blood. 2008;15:4117-4127.
-
(2008)
Blood
, vol.15
, pp. 4117-4127
-
-
Bystrom, J.1
Evans, I.2
Newson, J.3
Stables, M.4
Toor, I.5
Van Rn Crawford, M.6
Colville-Nash, P.7
Farrow, S.8
Gilroy, D.W.9
-
3
-
-
67650485985
-
Alternative Activation of Macro-phages: An Immunologic Functional Perspective
-
Martinez FO, Helming L, Gordon S. Alternative Activation of Macro-phages: An Immunologic Functional Perspective. Annu Rev Immunol. 2009;27:451-483.
-
(2009)
Annu Rev Immunol
, vol.27
, pp. 451-483
-
-
Martinez, F.O.1
Helming, L.2
Gordon, S.3
-
4
-
-
7644231561
-
The chemokine system in diverse forms of macrophage activation and polarization
-
Mantovani A, Sica A, Sozzani S, Allavena P, Vecchi A, Locati M. The chemokine system in diverse forms of macrophage activation and polarization. Trends Immunol. 2004;25:677-686.
-
(2004)
Trends Immunol
, vol.25
, pp. 677-686
-
-
Mantovani, A.1
Sica, A.2
Sozzani, S.3
Allavena, P.4
Vecchi, A.5
Locati, M.6
-
5
-
-
0035218631
-
Macrophage control of inflammation: Negative pathways of regulation of inflammatory cytokines
-
Mantovani A, Muzio M, Garlanda C, Sozzani S, Allavena P. Macrophage control of inflammation: negative pathways of regulation of inflammatory cytokines. Novartis Found Symp. 2001;234:120-131.
-
(2001)
Novartis Found Symp
, vol.234
, pp. 120-131
-
-
Mantovani, A.1
Muzio, M.2
Garlanda, C.3
Sozzani, S.4
Allavena, P.5
-
6
-
-
18944375453
-
Arginase-1 and Ym1 are markers for murine, but not human, alternatively activated myeloid cells
-
Raes G, Van den BR, De BP, Ghassabeh GH, Scotton C, Locati M, Mantovani A, Sozzani S. Arginase-1 and Ym1 are markers for murine, but not human, alternatively activated myeloid cells. J Immunol. 2005; 174:6561-6562.
-
(2005)
J Immunol
, vol.174
, pp. 6561-6562
-
-
Raes, G.1
Bp De Br V.Den2
Ghassabeh, G.H.3
Scotton, C.4
Locati, M.5
Mantovani, A.6
Sozzani, S.7
-
7
-
-
33751011025
-
Tumor macrophage redox and effector mechanisms associated with hypoxia
-
Espey MG. Tumor macrophage redox and effector mechanisms associated with hypoxia. Free Radic Biol Med. 2006;41:1621-1628.
-
(2006)
Free Radic Biol Med
, vol.41
, pp. 1621-1628
-
-
Espey, M.G.1
-
8
-
-
42049098600
-
Heterogeneity of human macrophages in culture and in atherosclerotic plaques
-
Waldo SW, Li Y, Buono C, Zhao B, Billings EM, Chang J, Kruth HS. Heterogeneity of human macrophages in culture and in atherosclerotic plaques. Am J Pathol. 2008;172:1112-1126.
-
(2008)
Am J Pathol
, vol.172
, pp. 1112-1126
-
-
Waldo, S.W.1
Li, Y.2
Buono, C.3
Zhao, B.4
Billings, E.M.5
Chang, J.6
Kruth, H.S.7
-
9
-
-
34547492488
-
PPARgamma activation primes human monocytes into alternative M2 macrophages with anti-inflammatory properties
-
Bouhlel MA, Derudas B, Rigamonti E, Dievart R, Brozek J, Haulon S, Zawadzki C, Jude B, Torpier G, Marx N, Staels B, Chinetti-Gbaguidi G. PPARgamma activation primes human monocytes into alternative M2 macrophages with anti-inflammatory properties. Cell Metab. 2007;6: 137-143.
-
(2007)
Cell Metab
, vol.6
, pp. 137-143
-
-
Bouhlel, M.A.1
Derudas, B.2
Rigamonti, E.3
Dievart, R.4
Brozek, J.5
Haulon, S.6
Zawadzki, C.7
Jude, B.8
Torpier, G.9
Marx, N.10
Staels, B.11
Chinetti-Gbaguidi, G.12
-
10
-
-
70349581878
-
Macrophage diversity and polarization in atherosclerosis: A question of balance
-
Mantovani A, Garlanda C, Locati M. Macrophage diversity and polarization in atherosclerosis: a question of balance. Arterioscler Thromb Vasc Biol. 2009;29:1419-1423.
-
(2009)
Arterioscler Thromb Vasc Biol
, vol.29
, pp. 1419-1423
-
-
Mantovani, A.1
Garlanda, C.2
Locati, M.3
-
11
-
-
0037071843
-
Subendothelial retention of atherogenic lipoproteins in early atherosclerosis
-
Skalen K, Gustafsson M, Rydberg EK, Hulten LM, Wiklund O, Innerarity TL, Boren J. Subendothelial retention of atherogenic lipoproteins in early atherosclerosis. Nature. 2002;417:750-754.
-
(2002)
Nature
, vol.417
, pp. 750-754
-
-
Skalen, K.1
Gustafsson, M.2
Rydberg, E.K.3
Hulten, L.M.4
Wiklund, O.5
Innerarity, T.L.6
Boren, J.7
-
12
-
-
0034648768
-
Atherosclerosis
-
Lusis AJ. Atherosclerosis. Nature. 2000;407:233-241.
-
(2000)
Nature
, vol.407
, pp. 233-241
-
-
Lusis, A.J.1
-
13
-
-
0033789652
-
Determinants of bioactivity of oxidized phospholipids. Specific oxidized fatty acyl groups at the sn-2 position
-
Subbanagounder G, Leitinger N, Schwenke DC, Wong JW, Lee H, Rizza C, Watson AD, Faull KF, Fogelman AM, Berliner JA. Determinants of bioactivity of oxidized phospholipids. Specific oxidized fatty acyl groups at the sn-2 position. Arterioscler Thromb Vasc Biol. 2000;20:2248-2254.
-
(2000)
Arterioscler Thromb Vasc Biol
, vol.20
, pp. 2248-2254
-
-
Subbanagounder, G.1
Leitinger, N.2
Schwenke, D.C.3
Wong, J.W.4
Lee, H.5
Rizza, C.6
Watson, A.D.7
Faull, K.F.8
Fogelman, A.M.9
Berliner, J.A.10
-
14
-
-
17944387960
-
Structural identification by mass spec-trometry of oxidized phospholipids in minimally oxidized low density lipoprotein that induce monocyte/endothelial interactions and evidence for their presence in vivo
-
Watson AD, Leitinger N, Navab M, Faull KF, Horkko S, Witztum JL, Palinski W, Schwenke D, Salomon RG, Sha W, Subbanagounder G, Fogelman AM, Berliner JA. Structural identification by mass spec-trometry of oxidized phospholipids in minimally oxidized low density lipoprotein that induce monocyte/endothelial interactions and evidence for their presence in vivo. J Biol Chem. 1997;272: 13597-13607.
-
(1997)
J Biol Chem
, vol.272
, pp. 13597-13607
-
-
Watson, A.D.1
Leitinger, N.2
Navab, M.3
Faull, K.F.4
Horkko, S.5
Witztum, J.L.6
Palinski, W.7
Schwenke, D.8
Salomon, R.G.9
Sha, W.10
Subbanagounder, G.11
Fogelman, A.M.12
Berliner, J.A.13
-
15
-
-
0033609897
-
Structural identification of a novel pro-inflammatory epoxyisoprostane phospholipid in mildly oxidized low density lipoprotein
-
Watson AD, Subbanagounder G, Welsbie DS, Faull KF, Navab M, Jung ME, Fogelman AM, Berliner JA. Structural identification of a novel pro-inflammatory epoxyisoprostane phospholipid in mildly oxidized low density lipoprotein. J Biol Chem. 1999;274:24787-24798.
-
(1999)
J Biol Chem
, vol.274
, pp. 24787-24798
-
-
Watson, A.D.1
Subbanagounder, G.2
Welsbie, D.S.3
Faull, K.F.4
Navab, M.5
Jung, M.E.6
Fogelman, A.M.7
Berliner, J.A.8
-
16
-
-
77949618571
-
Generation and biological activities of oxidized phospholipids
-
Bochkov VN, Oskolkova OV, Birukov KG, Levonen AL, Binder CJ, Stockl J. Generation and biological activities of oxidized phospholipids. Antioxid Redox Signal. 2010;12:1009-1059.
-
(2010)
Antioxid Redox Signal
, vol.12
, pp. 1009-1059
-
-
Bochkov, V.N.1
Oskolkova, O.V.2
Birukov, K.G.3
Levonen, A.L.4
Binder, C.J.5
Stockl, J.6
-
17
-
-
66049157165
-
Induction of CCR2-dependent macro-phage accumulation by oxidized phospholipids in the air-pouch model of inflammation
-
Kadl A, Galkina E, Leitinger N. Induction of CCR2-dependent macro-phage accumulation by oxidized phospholipids in the air-pouch model of inflammation. Arthritis Rheum. 2009;60:1362-1371.
-
(2009)
Arthritis Rheum
, vol.60
, pp. 1362-1371
-
-
Kadl, A.1
Galkina, E.2
Leitinger, N.3
-
18
-
-
67649402187
-
The Nrf2-antioxidant response element signaling pathway and its activation by oxidative stress
-
Nguyen T, Nioi P, Pickett CB. The Nrf2-antioxidant response element signaling pathway and its activation by oxidative stress. J Biol Chem. 2009;284:13291-13295.
-
(2009)
J Biol Chem
, vol.284
, pp. 13291-13295
-
-
Nguyen, T.1
Nioi, P.2
Pickett, C.B.3
-
19
-
-
0037026527
-
Protective role of phospholipid oxidation products in endotoxin-induced tissue damage
-
Bochkov VN, Kadl A, Huber J, Gruber F, Binder BR, Leitinger N. Protective role of phospholipid oxidation products in endotoxin-induced tissue damage. Nature. 2002;419:77-81.
-
(2002)
Nature
, vol.419
, pp. 77-81
-
-
Bochkov, V.N.1
Kadl, A.2
Huber, J.3
Gruber, F.4
Binder, B.R.5
Leitinger, N.6
-
20
-
-
0033543566
-
Nrf2, a Cap'n'Collar transcription factor, regulates induction of the heme ox-ygenase-1 gene
-
Alam J, Stewart D, Touchard C, Boinapally S, Choi AM, Cook JL. Nrf2, a Cap'n'Collar transcription factor, regulates induction of the heme ox-ygenase-1 gene. J Biol Chem. 1999;274:26071-26078.
-
(1999)
J Biol Chem
, vol.274
, pp. 26071-26078
-
-
Alam, J.1
Stewart, D.2
Touchard, C.3
Boinapally, S.4
Choi, A.M.5
Cook, J.L.6
-
21
-
-
18344387893
-
Redox-sensitive interaction between KIAA0132 and Nrf2 mediates indomethacin-induced expression of gamma-glutamylcysteine synthetase
-
Sekhar KR, Spitz DR, Harris S, Nguyen TT, Meredith MJ, Holt JT, Gius D, Marnett LJ, Summar ML, Freeman ML. Redox-sensitive interaction between KIAA0132 and Nrf2 mediates indomethacin-induced expression of gamma-glutamylcysteine synthetase. Free Radic Biol Med. 2002;32: 650-662.
-
(2002)
Free Radic Biol Med
, vol.32
, pp. 650-662
-
-
Sekhar, K.R.1
Spitz, D.R.2
Harris, S.3
Nguyen, T.T.4
Meredith, M.J.5
Holt, J.T.6
Gius, D.7
Marnett, L.J.8
Summar, M.L.9
Freeman, M.L.10
-
22
-
-
33645893202
-
Induction of AKR1C2 by phase II inducers: Identification of a distal consensus antioxidant response element (ARE) regulated by NRF2
-
Lou H, Du S, Ji Q, Stolz A. Induction of AKR1C2 by phase II inducers: identification of a distal consensus antioxidant response element (ARE) regulated by NRF2. Mol Pharmacol. 2006;69:1662-1672.
-
(2006)
Mol Pharmacol
, vol.69
, pp. 1662-1672
-
-
Lou, H.1
Du, S.2
Ji, Q.3
Stolz, A.4
-
24
-
-
0034963058
-
Regulation of LPS induced IL-12 production by IFN-gamma and IL-4 through intracellular glutathione status in human alveolar macrophages
-
Dobashi K, Aihara M, Araki T, Shimizu Y, Utsugi M, Iizuka K, Murata Y, Hamuro J, Nakazawa T, Mori M. Regulation of LPS induced IL-12 production by IFN-gamma and IL-4 through intracellular glutathione status in human alveolar macrophages. Clin Exp Immunol. 2001;124: 290-296.
-
(2001)
Clin Exp Immunol
, vol.124
, pp. 290-296
-
-
Dobashi, K.1
Aihara, M.2
Araki, T.3
Shimizu, Y.4
Utsugi, M.5
Iizuka, K.6
Murata, Y.7
Hamuro, J.8
Nakazawa, T.9
Mori, M.10
-
25
-
-
33646692002
-
Lymphocyte recruitment into the aortic wall before and during development of atherosclerosis is partially L-selectin dependent
-
Galkina E, Kadl A, Sanders J, Varughese D, Sarembock IJ, Ley K. Lymphocyte recruitment into the aortic wall before and during development of atherosclerosis is partially L-selectin dependent. J Exp Med. 2006;203:1273-1282.
-
(2006)
J Exp Med
, vol.203
, pp. 1273-1282
-
-
Galkina, E.1
Kadl, A.2
Sanders, J.3
Varughese, D.4
Sarembock, I.J.5
Ley, K.6
-
26
-
-
0042926424
-
The role of interleukin-4 and interleukin-12 in the progression of atherosclerosis in apolipoprotein E-deficient mice
-
Davenport P, Tipping PG. The role of interleukin-4 and interleukin-12 in the progression of atherosclerosis in apolipoprotein E-deficient mice. Am J Pathol. 2003;163:1117-1125.
-
(2003)
Am J Pathol
, vol.163
, pp. 1117-1125
-
-
Davenport, P.1
Tipping, P.G.2
-
27
-
-
65349166757
-
Macrophage apoptosis exerts divergent effects on atherogenesis as a function of lesion stage
-
Gautier EL, Huby T, Witztum JL, Ouzilleau B, Miller ER, Saint-Charles F, Aucouturier P, Chapman MJ, Lesnik P. Macrophage apoptosis exerts divergent effects on atherogenesis as a function of lesion stage. Circulation. 2009;119:1795-1804.
-
(2009)
Circulation
, vol.119
, pp. 1795-1804
-
-
Gautier, E.L.1
Huby, T.2
Witztum, J.L.3
Ouzilleau, B.4
Miller, E.R.5
Saint-Charles, F.6
Aucouturier, P.7
Chapman, M.J.8
Lesnik, P.9
-
28
-
-
0033595261
-
Interleukin-4-dependent production of PPAR-gamma ligands in macrophages by 12/15-lipoxygen-ase
-
Huang JT, Welch JS, Ricote M, Binder CJ, Willson TM, Kelly C, Witztum JL, Funk CD, Conrad D, Glass CK. Interleukin-4-dependent production of PPAR-gamma ligands in macrophages by 12/15-lipoxygen-ase. Nature. 1999;400:378-382.
-
(1999)
Nature
, vol.400
, pp. 378-382
-
-
Huang, J.T.1
Welch, J.S.2
Ricote, M.3
Binder, C.J.4
Willson, T.M.5
Kelly, C.6
Witztum, J.L.7
Funk, C.D.8
Conrad, D.9
Glass, C.K.10
-
29
-
-
61849091325
-
Impaired apoptotic cell clearance in CGD due to altered macrophage programming is reversed by phosphatidylserine-dependent production of IL-4
-
Fernandez-Boyanapalli RF, Frasch SC, McPhillips K, Vandivier RW, Harry BL, Riches DW, Henson PM, Bratton DL. Impaired apoptotic cell clearance in CGD due to altered macrophage programming is reversed by phosphatidylserine- dependent production of IL-4. Blood. 2009;113: 2047-2055.
-
(2009)
Blood
, vol.113
, pp. 2047-2055
-
-
Fernandez-Boyanapalli, R.F.1
Frasch, S.C.2
McPhillips, K.3
Vandivier, R.W.4
Harry, B.L.5
Riches, D.W.6
Henson, P.M.7
Bratton, D.L.8
-
30
-
-
33846263059
-
Van der PT. Oxidized phospholipids inhibit phagocytosis and impair outcome in gram-negative sepsis in vivo
-
Knapp S, Matt U, Leitinger N, van der PT. Oxidized phospholipids inhibit phagocytosis and impair outcome in gram-negative sepsis in vivo. J Immunol. 2007;178:993-1001.
-
(2007)
J Immunol
, vol.178
, pp. 993-1001
-
-
Knapp, S.1
Matt, U.2
Leitinger, N.3
-
31
-
-
66349092815
-
Tabas i Mechanisms and consequences of macrophage apo-ptosis in atherosclerosis
-
Seimon T, Tabas I Mechanisms and consequences of macrophage apo-ptosis in atherosclerosis. J Lipid Res. 2009;50(Suppl):S382-S387.
-
(2009)
J Lipid Res
, vol.50
, Issue.SUPPL.
-
-
Seimon, T.1
-
32
-
-
0035132330
-
PPAR-gamma dependent and independent effects on macrophage-gene expression in lipid metabolism and inflammation
-
Chawla A, Barak Y, Nagy L, Liao D, Tontonoz P, Evans RM. PPAR-gamma dependent and independent effects on macrophage-gene expression in lipid metabolism and inflammation. Nat Med. 2001;7: 48-52.
-
(2001)
Nat Med
, vol.7
, pp. 48-52
-
-
Chawla, A.1
Barak, Y.2
Nagy, L.3
Liao, D.4
Tontonoz, P.5
Evans, R.M.6
-
33
-
-
34347354309
-
Macrophage-specific PPARgamma controls alternative activation and improves insulin resistance
-
Odegaard JI, Ricardo-Gonzalez RR, Goforth MH, Morel CR, Subra-manian V, Mukundan L, Eagle AR, Vats D, Brombacher F, Ferrante AW, Chawla A. Macrophage-specific PPARgamma controls alternative activation and improves insulin resistance. Nature. 2007;447: 1116-1120.
-
(2007)
Nature
, vol.447
, pp. 1116-1120
-
-
Odegaard, J.I.1
Ricardo-Gonzalez, R.R.2
Goforth, M.H.3
Morel, C.R.4
Subra-Manian, V.5
Mukundan, L.6
Eagle, A.R.7
Vats, D.8
Brombacher, F.9
Ferrante, A.W.10
Chawla, A.11
-
34
-
-
23244451031
-
Conditional knockout of macrophage PPARgamma increases atherosclerosis in C57BL/6 and low-density lipoprotein receptor-deficient mice
-
Babaev VR, Yancey PG, Ryzhov SV, Kon V, Breyer MD, Magnuson MA, Fazio S, Linton MF. Conditional knockout of macrophage PPARgamma increases atherosclerosis in C57BL/6 and low-density lipoprotein receptor-deficient mice. Arterioscler Thromb Vasc Biol. 2005; 25:1647-1653.
-
(2005)
Arterioscler Thromb Vasc Biol
, vol.25
, pp. 1647-1653
-
-
Babaev, V.R.1
Yancey, P.G.2
Ryzhov, S.V.3
Kon, V.4
Breyer, M.D.5
Magnuson, M.A.6
Fazio, S.7
Linton, M.F.8
-
35
-
-
55949120110
-
Activation of Nrf2-antioxidant signaling attenuates NFkappaB-inflammatory response and elicits apoptosis
-
Li W, Khor TO, Xu C, Shen G, Jeong WS, Yu S, Kong AN. Activation of Nrf2-antioxidant signaling attenuates NFkappaB-inflammatory response and elicits apoptosis. Biochem Pharmacol. 2008;76:1485-1489.
-
(2008)
Biochem Pharmacol
, vol.76
, pp. 1485-1489
-
-
Li, W.1
Khor, T.O.2
Xu, C.3
Shen, G.4
Jeong, W.S.5
Yu, S.6
Kong, A.N.7
-
36
-
-
3042794972
-
Unique function of the Nrf2-Keap1 pathway in the inducible expression of antioxidant and detoxifying enzymes
-
Kobayashi A, Ohta T, Yamamoto M. Unique function of the Nrf2-Keap1 pathway in the inducible expression of antioxidant and detoxifying enzymes. Methods Enzymol. 2004;378:273-286.
-
(2004)
Methods Enzymol
, vol.378
, pp. 273-286
-
-
Kobayashi, A.1
Ohta, T.2
Yamamoto, M.3
-
37
-
-
0032953192
-
Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain
-
Itoh K, Wakabayashi N, Katoh Y, Ishii T, Igarashi K, Engel JD, Yamamoto M. Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain. Genes Dev. 1999;13:76-86.
-
(1999)
Genes Dev
, vol.13
, pp. 76-86
-
-
Itoh, K.1
Wakabayashi, N.2
Katoh, Y.3
Ishii, T.4
Igarashi, K.5
Engel, J.D.6
Yamamoto, M.7
-
38
-
-
33845442925
-
Mechanistic studies of the Nrf2-Keap1 signaling pathway
-
Zhang DD. Mechanistic studies of the Nrf2-Keap1 signaling pathway. Drug Metab Rev. 2006;38:769-789.
-
(2006)
Drug Metab Rev
, vol.38
, pp. 769-789
-
-
Zhang, D.D.1
-
39
-
-
75149178692
-
NF-E2-related factor 2 regulates the stress response to UVA-1-oxidized phospholipids in skin cells
-
Gruber F, Mayer H, Lengauer B, Mlitz V, Sanders JM, Kadl A, Bilban M, de MR, Wagner O, Kensler TW, Yamamoto M, Leitinger N, Tschachler E. NF-E2-related factor 2 regulates the stress response to UVA-1-oxidized phospholipids in skin cells. FASEB J. 2010;24:39-48.
-
(2010)
FASEB J.
, vol.24
, pp. 39-48
-
-
Gruber, F.1
Mayer, H.2
Lengauer, B.3
Mlitz, V.4
Sanders, J.M.5
Kadl, A.6
Bilban, M.7
De Mr Wagner, O.8
Kensler, T.W.9
Yamamoto, M.10
Leitinger, N.11
Tschachler, E.12
-
40
-
-
48049102141
-
Nrf2 regulates antioxidant gene expression evoked by oxidized phospholipids in endothelial cells and murine arteries in vivo
-
Jyrkkanen HK, Kansanen E, Inkala M, Kivela AM, Hurttila H, Heinonen SE, Goldsteins G, Jauhiainen S, Tiainen S, Makkonen H, Oskolkova O, Afonyushkin T, Koistinaho J, Yamamoto M, Bochkov VN, Yla-Herttuala S, Levonen AL. Nrf2 regulates antioxidant gene expression evoked by oxidized phospholipids in endothelial cells and murine arteries in vivo. Circ Res. 2008;103:e1-e9.
-
(2008)
Circ Res
, vol.103
-
-
Jyrkkanen, H.K.1
Kansanen, E.2
Inkala, M.3
Kivela, A.M.4
Hurttila, H.5
Heinonen, S.E.6
Goldsteins, G.7
Jauhiainen, S.8
Tiainen, S.9
Makkonen, H.10
Oskolkova, O.11
Afonyushkin, T.12
Koistinaho, J.13
Yamamoto, M.14
Bochkov, V.N.15
Yla-Herttuala, S.16
Levonen, A.L.17
-
41
-
-
42449119839
-
Accumulation of 15-deoxy-delta(12,14)-prostaglandin J2 adduct formation with Keap1 over time: Effects on potency for intracellular antioxidant defence induction
-
Oh JY, Giles N, Landar A, rley-Usmar V. Accumulation of 15-deoxy-delta(12,14)-prostaglandin J2 adduct formation with Keap1 over time: effects on potency for intracellular antioxidant defence induction. Biochem J. 2008;411:297-306.
-
(2008)
Biochem J
, vol.411
, pp. 297-306
-
-
Oh, J.Y.1
Giles, N.2
Landar, A.3
Rley-Usmar, V.4
-
42
-
-
0347359124
-
Signal transduction pathways activated in human pulmonary endothelial cells by OxPAPC, a bioactive component of oxidized lipoproteins
-
Birukov KG, Leitinger N, Bochkov VN, Garcia JG. Signal transduction pathways activated in human pulmonary endothelial cells by OxPAPC, a bioactive component of oxidized lipoproteins. Microvasc Res. 2004;67: 18-28.
-
(2004)
Microvasc Res
, vol.67
, pp. 18-28
-
-
Birukov, K.G.1
Leitinger, N.2
Bochkov, V.N.3
Garcia, J.G.4
-
43
-
-
34547676833
-
15d-PGJ2 stimulates HO-1 expression through p38 MAP kinase and Nrf-2 pathway in rat vascular smooth muscle cells
-
Lim HJ, Lee KS, Lee S, Park JH, Choi HE, Go SH, Kwak HJ, Park HY. 15d-PGJ2 stimulates HO-1 expression through p38 MAP kinase and Nrf-2 pathway in rat vascular smooth muscle cells. Toxicol Appl Pharmacol. 2007;223:20-27.
-
(2007)
Toxicol Appl Pharmacol
, vol.223
, pp. 20-27
-
-
Lim, H.J.1
Lee, K.S.2
Lee, S.3
Park, J.H.4
Choi, H.E.5
Go, S.H.6
Kwak, H.J.7
Park, H.Y.8
-
44
-
-
34948853738
-
Tumor cell apoptosis polarizes macrophages role of sphingosine-1- phosphate
-
Weigert A, Tzieply N, von KA, Johann AM, Schmidt H, Geisslinger G, Brune B. Tumor cell apoptosis polarizes macrophages role of sphingosine-1-phosphate. Mol Biol Cell. 2007;18:3810-3819.
-
(2007)
Mol Biol Cell
, vol.18
, pp. 3810-3819
-
-
Weigert, A.1
Tzieply, N.2
Von Ka Johann, A.M.3
Schmidt, H.4
Geisslinger, G.5
Brune, B.6
-
45
-
-
33748178875
-
Apoptotic cells promote macrophage survival by releasing the antiapoptotic mediator sphingosine-1-phosphate
-
Weigert A, Johann AM, von Knethen A, Schmidt H, Geisslinger G, Brune B. Apoptotic cells promote macrophage survival by releasing the antiapoptotic mediator sphingosine-1-phosphate. Blood. 2006;108: 1635-1642.
-
(2006)
Blood
, vol.108
, pp. 1635-1642
-
-
Weigert, A.1
Johann, A.M.2
Von Knethen, A.3
Schmidt, H.4
Geisslinger, G.5
Brune, B.6
-
46
-
-
65249113865
-
Heme oxygenase-1 contributes to an alternative macrophage activation profile induced by apoptotic cell supernatants
-
Weis N, Weigert A, von KA, Brune B. Heme oxygenase-1 contributes to an alternative macrophage activation profile induced by apoptotic cell supernatants. Mol Biol Cell. 2009;20:1280-1288.
-
(2009)
Mol Biol Cell
, vol.20
, pp. 1280-1288
-
-
Weis, N.1
Weigert, A.2
Von Ka Brune, B.3
-
47
-
-
42549148380
-
Sphingosine-1-phosphate induces an antiinflammatory phenotype in mac-rophages
-
Hughes JE, Srinivasan S, Lynch KR, Proia RL, Ferdek P, Hedrick CC. Sphingosine-1-phosphate induces an antiinflammatory phenotype in mac-rophages. Circ Res. 2008;102:950-958.
-
(2008)
Circ Res
, vol.102
, pp. 950-958
-
-
Hughes, J.E.1
Srinivasan, S.2
Lynch, K.R.3
Proia, R.L.4
Ferdek, P.5
Hedrick, C.C.6
-
48
-
-
33847670874
-
Microarray analysis reveals overexpression of CD163 and HO-1 in symptomatic carotid plaques
-
Ijas P, Nuotio K, Saksi J, Soinne L, Saimanen E, Karjalainen-Lindsberg ML, Salonen O, Sarna S, Tuimala J, Kovanen PT, Kaste M, Lindsberg PJ. Microarray analysis reveals overexpression of CD163 and HO-1 in symptomatic carotid plaques. Arterioscler Thromb Vasc Biol. 2007;27: 154-160.
-
(2007)
Arterioscler Thromb Vasc Biol
, vol.27
, pp. 154-160
-
-
Ijas, P.1
Nuotio, K.2
Saksi, J.3
Soinne, L.4
Saimanen, E.5
Karjalainen-Lindsberg, M.L.6
Salonen, O.7
Sarna, S.8
Tuimala, J.9
Kovanen, P.T.10
Kaste, M.11
Lindsberg, P.J.12
-
49
-
-
63849091619
-
Macro-phage antioxidant protection within atherosclerotic plaques
-
Gieseg SP, Leake DS, Flavall EM, Amit Z, Reid L, Yang YT. Macro-phage antioxidant protection within atherosclerotic plaques. Front Biosci. 2009;14:1230-1246.
-
(2009)
Front Biosci
, vol.14
, pp. 1230-1246
-
-
Gieseg, S.P.1
Leake, D.S.2
Flavall, E.M.3
Amit, Z.4
Reid, L.5
Yang, Y.T.6
-
50
-
-
34250359779
-
Emerging role of Nrf2 in protecting against hepatic and gastrointestinal disease
-
Aleksunes LM, Manautou JE. Emerging role of Nrf2 in protecting against hepatic and gastrointestinal disease. Toxicol Pathol. 2007;35:459-473.
-
(2007)
Toxicol Pathol
, vol.35
, pp. 459-473
-
-
Aleksunes, L.M.1
Manautou, J.E.2
-
51
-
-
29244473882
-
Nrf2-deficient mice are highly susceptible to cigarette smoke-induced emphysema
-
Iizuka T, Ishii Y, Itoh K, Kiwamoto T, Kimura T, Matsuno Y, Morishima Y, Hegab AE, Homma S, Nomura A, Sakamoto T, Shimura M, Yoshida A, Yamamoto M, Sekizawa K. Nrf2-deficient mice are highly susceptible to cigarette smoke-induced emphysema. Genes Cells. 2005;10: 1113-1125.
-
(2005)
Genes Cells
, vol.10
, pp. 1113-1125
-
-
Iizuka, T.1
Ishii, Y.2
Itoh, K.3
Kiwamoto, T.4
Kimura, T.5
Matsuno, Y.6
Morishima, Y.7
Hegab, A.E.8
Homma, S.9
Nomura, A.10
Sakamoto, T.11
Shimura, M.12
Yoshida, A.13
Yamamoto, M.14
Sekizawa, K.15
-
52
-
-
47949083810
-
The transcription factor Nrf2 is a therapeutic target against brain inflammation
-
Innamorato NG, Rojo AI, Garcia-Yague AJ, Yamamoto M, de Ceballos ML, Cuadrado A. The transcription factor Nrf2 is a therapeutic target against brain inflammation. J Immunol. 2008;181:680-689.
-
(2008)
J Immunol
, vol.181
, pp. 680-689
-
-
Innamorato, N.G.1
Rojo, A.I.2
Garcia-Yague, A.J.3
Yamamoto, M.4
De Ceballos, M.L.5
Cuadrado, A.6
-
53
-
-
4844225631
-
Genetic dissection of systemic autoimmune disease in Nrf2-deficient mice
-
Li J, Stein TD, Johnson JA. Genetic dissection of systemic autoimmune disease in Nrf2-deficient mice. Physiol Genomics. 2004;18:261-272.
-
(2004)
Physiol Genomics
, vol.18
, pp. 261-272
-
-
Li, J.1
Stein, T.D.2
Johnson, J.A.3
-
54
-
-
49149126354
-
Disruption of Nrf2 enhances susceptibility to airway inflammatory responses induced by low-dose diesel exhaust particles in mice
-
Li YJ, Takizawa H, Azuma A, Kohyama T, Yamauchi Y, Takahashi S, Yamamoto M, Kawada T, Kudoh S, Sugawara I. Disruption of Nrf2 enhances susceptibility to airway inflammatory responses induced by low-dose diesel exhaust particles in mice. Clin Immunol. 2008;128: 366-373.
-
(2008)
Clin Immunol
, vol.128
, pp. 366-373
-
-
Li, Y.J.1
Takizawa, H.2
Azuma, A.3
Kohyama, T.4
Yamauchi, Y.5
Takahashi, S.6
Yamamoto, M.7
Kawada, T.8
Kudoh, S.9
Sugawara, I.10
-
55
-
-
21144456105
-
Role of 15-deoxy delta(12,14) prostaglandin J2 and Nrf2 pathways in protection against acute lung injury
-
Mochizuki M, Ishii Y, Itoh K, Iizuka T, Morishima Y, Kimura T, Kiwamoto T, Matsuno Y, Hegab AE, Nomura A, Sakamoto T, Uchida K, Yamamoto M, Sekizawa K. Role of 15-deoxy delta(12,14) prostaglandin J2 and Nrf2 pathways in protection against acute lung injury. Am J Respir Crit Care Med. 2005;171:1260-1266.
-
(2005)
Am J Respir Crit Care Med
, vol.171
, pp. 1260-1266
-
-
Mochizuki, M.1
Ishii, Y.2
Itoh, K.3
Iizuka, T.4
Morishima, Y.5
Kimura, T.6
Kiwamoto, T.7
Matsuno, Y.8
Hegab, A.E.9
Nomura, A.10
Sakamoto, T.11
Uchida, K.12
Yamamoto, M.13
Sekizawa, K.14
-
56
-
-
0035853157
-
Sensitivity to carcinogenesis is increased and chemopro-tective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice
-
Ramos-Gomez M, Kwak MK, Dolan PM, Itoh K, Yamamoto M, Talalay P, Kensler TW. Sensitivity to carcinogenesis is increased and chemopro-tective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice. Proc Natl Acad Sci\USA. 2001;98:3410-3415.
-
(2001)
Proc Natl Acad Sci\USA
, vol.98
, pp. 3410-3415
-
-
Ramos-Gomez, M.1
Kwak, M.K.2
Dolan, P.M.3
Itoh, K.4
Yamamoto, M.5
Talalay, P.6
Kensler, T.W.7
-
57
-
-
0034785941
-
Nrf2-deficient female mice develop lupus-like autoimmune nephritis
-
Yoh K, Itoh K, Enomoto A, Hirayama A, Yamaguchi N, Kobayashi M, Morito N, Koyama A, Yamamoto M, Takahashi S. Nrf2-deficient female mice develop lupus-like autoimmune nephritis. Kidney Int. 2001;60: 1343-1353.
-
(2001)
Kidney Int
, vol.60
, pp. 1343-1353
-
-
Yoh, K.1
Itoh, K.2
Enomoto, A.3
Hirayama, A.4
Yamaguchi, N.5
Kobayashi, M.6
Morito, N.7
Koyama, A.8
Yamamoto, M.9
Takahashi, S.10
-
58
-
-
27844612530
-
Nrf2 as a target for cancer chemoprevention
-
Yu X, Kensler T. Nrf2 as a target for cancer chemoprevention. Mutat Res. 2005;591:93-102.
-
(2005)
Mutat Res
, vol.591
, pp. 93-102
-
-
Yu, X.1
Kensler, T.2
-
59
-
-
38149075947
-
The relationship between Helicobacter pylori infection and promoter polymorphism of the Nrf2 gene in chronic gastritis
-
Arisawa T, Tahara T, Shibata T, Nagasaka M, Nakamura M, Kamiya Y, Fujita H, Hasegawa S, Takagi T, Wang FY, Hirata I, Nakano H. The relationship between Helicobacter pylori infection and promoter polymorphism of the Nrf2 gene in chronic gastritis. Int J Mol Med. 2007;19: 143-148.
-
(2007)
Int J Mol Med
, vol.19
, pp. 143-148
-
-
Arisawa, T.1
Tahara, T.2
Shibata, T.3
Nagasaka, M.4
Nakamura, M.5
Kamiya, Y.6
Fujita, H.7
Hasegawa, S.8
Takagi, T.9
Wang, F.Y.10
Hirata, I.11
Nakano, H.12
-
60
-
-
34347392512
-
Functional polymorphisms in the transcription factor NRF2 in humans increase the risk of acute lung injury
-
Marzec JM, Christie JD, Reddy SP, Jedlicka AE, Vuong H, Lanken PN, Aplenc R, Yamamoto T, Yamamoto M, Cho HY, Kleeberger SR. Functional polymorphisms in the transcription factor NRF2 in humans increase the risk of acute lung injury. FASEB J. 2007;21:2237-2246.
-
(2007)
FASEB J
, vol.21
, pp. 2237-2246
-
-
Marzec, J.M.1
Christie, J.D.2
Reddy, S.P.3
Jedlicka, A.E.4
Vuong, H.5
Lanken, P.N.6
Aplenc, R.7
Yamamoto, T.8
Yamamoto, M.9
Cho, H.Y.10
Kleeberger, S.R.11
-
61
-
-
56849124834
-
Disruption of Nrf2, a key inducer of antioxidant defenses, attenuates ApoE-mediated atherosclerosis in mice
-
Sussan TE, Jun J, Thimmulappa R, Bedja D, Antero M, Gabrielson KL, Polotsky VY, Biswal S. Disruption of Nrf2, a key inducer of antioxidant defenses, attenuates ApoE-mediated atherosclerosis in mice. PLoS ONE. 2008;3:e3791.
-
(2008)
PLoS ONE
, vol.3
-
-
Sussan, T.E.1
Jun, J.2
Thimmulappa, R.3
Bedja, D.4
Antero, M.5
Gabrielson, K.L.6
Polotsky, V.Y.7
Biswal, S.8
-
62
-
-
14644388840
-
Oxidized phospholipids trigger atherogenic inflammation in murine arteries
-
Furnkranz A, Schober A, Bochkov VN, Bashtrykov P, Kronke G, Kadl A, Binder BR, Weber C, Leitinger N. Oxidized phospholipids trigger atherogenic inflammation in murine arteries. Arterioscler Thromb Vasc Biol. 2005;25:633-638.
-
(2005)
Arterioscler Thromb Vasc Biol
, vol.25
, pp. 633-638
-
-
Furnkranz, A.1
Schober, A.2
Bochkov, V.N.3
Bashtrykov, P.4
Kronke, G.5
Kadl, A.6
Binder, B.R.7
Weber, C.8
Leitinger, N.9
-
63
-
-
62549114844
-
Coronary intraplaque hemorrhage evokes a novel atheroprotective macrophage phenotype
-
Boyle JJ, Harrington HA, Piper E, Elderfield K, Stark J, Landis RC, Haskard DO. Coronary intraplaque hemorrhage evokes a novel atheroprotective macrophage phenotype. Am J Pathol. 2009;174: 1097-1108.
-
(2009)
Am J Pathol
, vol.174
, pp. 1097-1108
-
-
Boyle, J.J.1
Harrington, H.A.2
Piper, E.3
Elderfield, K.4
Stark, J.5
Landis, R.C.6
Haskard, D.O.7
-
64
-
-
0347951196
-
Hemoglobin scavenger receptor CD163 mediates interleukin-10 release and heme oxygenase-1 synthesis: Antiinflammatory monocyte-macrophage responses in vitro, in resolving skin blisters in vivo, and after cardiopulmonary bypass surgery
-
Philippidis P, Mason JC, Evans BJ, Nadra I, Taylor KM, Haskard DO, Landis RC. Hemoglobin scavenger receptor CD163 mediates interleukin-10 release and heme oxygenase-1 synthesis: antiinflammatory monocyte-macrophage responses in vitro, in resolving skin blisters in vivo, and after cardiopulmonary bypass surgery. Circ Res. 2004;94:119-126.
-
(2004)
Circ Res
, vol.94
, pp. 119-126
-
-
Philippidis, P.1
Mason, J.C.2
Evans, B.J.3
Nadra, I.4
Taylor, K.M.5
Haskard, D.O.6
Landis, R.C.7
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