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Volumn 61, Issue 11, 2012, Pages 2718-2727

Toll-like receptor 4 deficiency promotes the alternative activation of adipose tissue macrophages

Author keywords

[No Author keywords available]

Indexed keywords

ACYL COENZYME A OXIDASE; ADIPONECTIN; CARNITINE PALMITOYLTRANSFERASE I; CD163 ANTIGEN; CD68 ANTIGEN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; STEAROYL COENZYME A; STEROL REGULATORY ELEMENT BINDING PROTEIN; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA;

EID: 84868026167     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db11-1595     Document Type: Article
Times cited : (134)

References (33)
  • 1
    • 0027459878 scopus 로고
    • Adipose expression of tumor necrosis factor-alpha: Direct role in obesity-linked insulin resistance
    • Hotamisligil GS, Shargill NS, Spiegelman BM. Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance. Science 1993;259:87-91
    • (1993) Science , vol.259 , pp. 87-91
    • Hotamisligil, G.S.1    Shargill, N.S.2    Spiegelman, B.M.3
  • 3
    • 0030831210 scopus 로고    scopus 로고
    • A human homologue of the drosophila toll protein signals activation of adaptive immunity
    • Medzhitov R, Preston-Hurlburt P, Janeway CA Jr. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. Nature 1997;388:394-397
    • (1997) Nature , vol.388 , pp. 394-397
    • Medzhitov, R.1    Preston-Hurlburt, P.2    Janeway Jr., C.A.3
  • 4
    • 0035907302 scopus 로고    scopus 로고
    • Saturated fatty acids, but not unsaturated fatty acids, induce the expression of cyclooxygenase-2 mediated through toll-like receptor 4
    • Lee JY, Sohn KH, Rhee SH, Hwang D. Saturated fatty acids, but not unsaturated fatty acids, induce the expression of cyclooxygenase-2 mediated through Toll-like receptor 4. J Biol Chem 2001;276:16683-16689
    • (2001) J Biol Chem , vol.276 , pp. 16683-16689
    • Lee, J.Y.1    Sohn, K.H.2    Rhee, S.H.3    Hwang, D.4
  • 5
    • 37549013749 scopus 로고    scopus 로고
    • Inhibition or deletion of the lipopolysaccharide receptor toll-like receptor-4 confers partial protection against lipid-induced insulin resistance in rodent skeletal muscle
    • Radin MS, Sinha S, Bhatt BA, Dedousis N, O'Doherty RM. Inhibition or deletion of the lipopolysaccharide receptor Toll-like receptor-4 confers partial protection against lipid-induced insulin resistance in rodent skeletal muscle. Diabetologia 2008;51:336-346
    • (2008) Diabetologia , vol.51 , pp. 336-346
    • Radin, M.S.1    Sinha, S.2    Bhatt, B.A.3    Dedousis, N.4    O'Doherty, R.M.5
  • 6
    • 34247884376 scopus 로고    scopus 로고
    • C3H/HeJ mice carrying a toll-like receptor 4 mutation are protected against the development of insulin resistance in white adipose tissue in response to a high-fat diet
    • Poggi M, Bastelica D, Gual P, et al. C3H/HeJ mice carrying a toll-like receptor 4 mutation are protected against the development of insulin resistance in white adipose tissue in response to a high-fat diet. Diabetologia 2007;50:1267-1276
    • (2007) Diabetologia , vol.50 , pp. 1267-1276
    • Poggi, M.1    Bastelica, D.2    Gual, P.3
  • 7
    • 34547602916 scopus 로고    scopus 로고
    • Loss-of-function mutation in toll-like receptor 4 prevents diet-induced obesity and insulin resistance
    • Tsukumo DML, Carvalho-Filho MA, Carvalheira JBC, et al. Loss-of-function mutation in Toll-like receptor 4 prevents diet-induced obesity and insulin resistance. Diabetes 2007;56:1986-1998
    • (2007) Diabetes , vol.56 , pp. 1986-1998
    • Tsukumo, D.M.L.1    Carvalho-Filho, M.A.2    Carvalheira, J.B.C.3
  • 8
    • 77951918926 scopus 로고    scopus 로고
    • Macrophages, inflammation, and insulin resistance
    • Olefsky JM, Glass CK. Macrophages, inflammation, and insulin resistance. Annu Rev Physiol 2010;72:219-246
    • (2010) Annu Rev Physiol , vol.72 , pp. 219-246
    • Olefsky, J.M.1    Glass, C.K.2
  • 9
    • 77954672503 scopus 로고    scopus 로고
    • Adipose tissue macrophages: Their role in adipose tissue remodeling
    • Suganami T, Ogawa Y. Adipose tissue macrophages: their role in adipose tissue remodeling. J Leukoc Biol 2010;88:33-39
    • (2010) J Leukoc Biol , vol.88 , pp. 33-39
    • Suganami, T.1    Ogawa, Y.2
  • 11
    • 33846302361 scopus 로고    scopus 로고
    • Attenuation of obesity-induced adipose tissue inflammation in C3H/HeJ mice carrying a tolllike receptor 4 mutation
    • Suganami T, Mieda T, Itoh M, Shimoda Y, Kamei Y, Ogawa Y. Attenuation of obesity-induced adipose tissue inflammation in C3H/HeJ mice carrying a Tolllike receptor 4 mutation. Biochem Biophys Res Commun 2007;354:45-49
    • (2007) Biochem Biophys Res Commun , vol.354 , pp. 45-49
    • Suganami, T.1    Mieda, T.2    Itoh, M.3    Shimoda, Y.4    Kamei, Y.5    Ogawa, Y.6
  • 12
    • 67949091182 scopus 로고    scopus 로고
    • Activating transcription factor 3 constitutes a negative feedback mechanism that attenuates saturated fatty acid/toll-like receptor 4 signaling and macrophage activation in obese adipose tissue
    • Suganami T, Yuan X, Shimoda Y, et al. Activating transcription factor 3 constitutes a negative feedback mechanism that attenuates saturated fatty acid/Toll-like receptor 4 signaling and macrophage activation in obese adipose tissue. Circ Res 2009;105:25-32
    • (2009) Circ Res , vol.105 , pp. 25-32
    • Suganami, T.1    Yuan, X.2    Shimoda, Y.3
  • 13
    • 58149476609 scopus 로고    scopus 로고
    • Impact of macrophage toll-like receptor 4 deficiency on macrophage infiltration into adipose tissue and the artery wall in mice
    • Coenen KR, Gruen ML, Lee-Young RS, Puglisi MJ, Wasserman DH, Hasty AH. Impact of macrophage Toll-like receptor 4 deficiency on macrophage infiltration into adipose tissue and the artery wall in mice. Diabetologia 2009;52: 318-328
    • (2009) Diabetologia , vol.52 , pp. 318-328
    • Coenen, K.R.1    Gruen, M.L.2    Lee-Young, R.S.3    Puglisi, M.J.4    Wasserman, D.H.5    Hasty, A.H.6
  • 14
    • 79959216069 scopus 로고    scopus 로고
    • Adipose tissue macrophages: Phenotypic plasticity and diversity in lean and obese states
    • Morris DL, Singer K, Lumeng CN. Adipose tissue macrophages: phenotypic plasticity and diversity in lean and obese states. Curr Opin Clin Nutr Metab Care 2011;14:341-346
    • (2011) Curr Opin Clin Nutr Metab Care , vol.14 , pp. 341-346
    • Morris, D.L.1    Singer, K.2    Lumeng, C.N.3
  • 15
    • 73949125691 scopus 로고    scopus 로고
    • MGL1 promotes adipose tissue inflammation and insulin resistance by regulating 7/4hi monocytes in obesity
    • Westcott DJ, Delproposto JB, Geletka LM, et al. MGL1 promotes adipose tissue inflammation and insulin resistance by regulating 7/4hi monocytes in obesity. J Exp Med 2009;206:3143-3156
    • (2009) J Exp Med , vol.206 , pp. 3143-3156
    • Westcott, D.J.1    Delproposto, J.B.2    Geletka, L.M.3
  • 16
    • 33847393688 scopus 로고    scopus 로고
    • Diet-induced increases in adiposity, but not plasma lipids, promote macrophage infiltration into white adipose tissue
    • Coenen KR, Gruen ML, Chait A, Hasty AH. Diet-induced increases in adiposity, but not plasma lipids, promote macrophage infiltration into white adipose tissue. Diabetes 2007;56:564-573
    • (2007) Diabetes , vol.56 , pp. 564-573
    • Coenen, K.R.1    Gruen, M.L.2    Chait, A.3    Hasty, A.H.4
  • 17
    • 73949094213 scopus 로고    scopus 로고
    • Inhibition of long-chain acyl coenzyme A synthetases during fatty acid loading induces lipotoxicity in macrophages
    • Saraswathi V, Hasty AH. Inhibition of long-chain acyl coenzyme A synthetases during fatty acid loading induces lipotoxicity in macrophages. Arterioscler Thromb Vasc Biol 2009;29:1937-1943
    • (2009) Arterioscler Thromb Vasc Biol , vol.29 , pp. 1937-1943
    • Saraswathi, V.1    Hasty, A.H.2
  • 18
    • 77956836852 scopus 로고    scopus 로고
    • Absence of macrophage inflammatory protein-1a does not impact macrophage accumulation in adipose tissue of diet-induced obese mice
    • Surmi BK, Webb CD, Ristau AC, Hasty AH. Absence of macrophage inflammatory protein-1a does not impact macrophage accumulation in adipose tissue of diet-induced obese mice. Am J Physiol Endocrinol Metab 2010;299:E437-E445.
    • (2010) Am J Physiol Endocrinol Metab , vol.299
    • Surmi, B.K.1    Webb, C.D.2    Ristau, A.C.3    Hasty, A.H.4
  • 19
    • 33746098574 scopus 로고    scopus 로고
    • The role of lipolysis in mediating the proinflammatory effects of very low density lipoproteins in mouse peritoneal macrophages
    • Saraswathi V, Hasty AH. The role of lipolysis in mediating the proinflammatory effects of very low density lipoproteins in mouse peritoneal macrophages. J Lipid Res 2006;47:1406-1415
    • (2006) J Lipid Res , vol.47 , pp. 1406-1415
    • Saraswathi, V.1    Hasty, A.H.2
  • 20
    • 72249092930 scopus 로고    scopus 로고
    • Dietary fish oil exerts hypolipidemic effects in lean and insulin sensitizing effects in obese LDLR-/-mice
    • Saraswathi V, Morrow JD, Hasty AH. Dietary fish oil exerts hypolipidemic effects in lean and insulin sensitizing effects in obese LDLR-/-mice. J Nutr 2009;139:2380-2386
    • (2009) J Nutr , vol.139 , pp. 2380-2386
    • Saraswathi, V.1    Morrow, J.D.2    Hasty, A.H.3
  • 21
    • 33644778829 scopus 로고    scopus 로고
    • Considerations in the design of hyperinsulinemic-euglycemic clamps in the conscious mouse
    • Ayala JE, Bracy DP, McGuinness OP, Wasserman DH. Considerations in the design of hyperinsulinemic-euglycemic clamps in the conscious mouse. Diabetes 2006;55:390-397
    • (2006) Diabetes , vol.55 , pp. 390-397
    • Ayala, J.E.1    Bracy, D.P.2    McGuinness, O.P.3    Wasserman, D.H.4
  • 22
    • 34047094881 scopus 로고    scopus 로고
    • Chronic treatment with sildenafil improves energy balance and insulin action in high fat-fed conscious mice
    • Ayala JE, Bracy DP, Julien BM, Rottman JN, Fueger PT, Wasserman DH. Chronic treatment with sildenafil improves energy balance and insulin action in high fat-fed conscious mice. Diabetes 2007;56:1025-1033
    • (2007) Diabetes , vol.56 , pp. 1025-1033
    • Ayala, J.E.1    Bracy, D.P.2    Julien, B.M.3    Rottman, J.N.4    Fueger, P.T.5    Wasserman, D.H.6
  • 24
    • 0141844653 scopus 로고    scopus 로고
    • Reciprocal modulation of toll-like receptor-4 signaling pathways involving MyD88 and phosphatidylinositol 3-kinase/AKT by saturated and polyunsaturated fatty acids
    • Lee JY, Ye J, Gao Z, et al. Reciprocal modulation of Toll-like receptor-4 signaling pathways involving MyD88 and phosphatidylinositol 3-kinase/AKT by saturated and polyunsaturated fatty acids. J Biol Chem 2003;278: 37041-37051
    • (2003) J Biol Chem , vol.278 , pp. 37041-37051
    • Lee, J.Y.1    Ye, J.2    Gao, Z.3
  • 25
    • 0035204665 scopus 로고    scopus 로고
    • Modulation of the expression of cyclooxygenase-2 by fatty acids mediated through toll-like receptor 4-derived signaling pathways
    • Hwang D. Modulation of the expression of cyclooxygenase-2 by fatty acids mediated through toll-like receptor 4-derived signaling pathways. FASEB J 2001;15:2556-2564
    • (2001) FASEB J , vol.15 , pp. 2556-2564
    • Hwang, D.1
  • 26
    • 58849149821 scopus 로고    scopus 로고
    • Saturated fatty acids produce an inflammatory response predominantly through the activation of TLR4 signaling in hypothalamus: Implications for the pathogenesis of obesity
    • Milanski M, Degasperi G, Coope A, et al. Saturated fatty acids produce an inflammatory response predominantly through the activation of TLR4 signaling in hypothalamus: implications for the pathogenesis of obesity. J Neurosci 2009;29:359-370
    • (2009) J Neurosci , vol.29 , pp. 359-370
    • Milanski, M.1    Degasperi, G.2    Coope, A.3
  • 27
    • 73949110679 scopus 로고    scopus 로고
    • Saturated fatty acids do not directly stimulate toll-like receptor signaling
    • Erridge C, Samani NJ. Saturated fatty acids do not directly stimulate Toll-like receptor signaling. Arterioscler Thromb Vasc Biol 2009;29: 1944-1949
    • (2009) Arterioscler Thromb Vasc Biol , vol.29 , pp. 1944-1949
    • Erridge, C.1    Samani, N.J.2
  • 28
    • 48249125862 scopus 로고    scopus 로고
    • Changes in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat diet-induced obesity and diabetes in mice
    • Cani PD, Bibiloni R, Knauf C, et al. Changes in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat diet-induced obesity and diabetes in mice. Diabetes 2008;57:1470-1481
    • (2008) Diabetes , vol.57 , pp. 1470-1481
    • Cani, P.D.1    Bibiloni, R.2    Knauf, C.3
  • 29
    • 44449110675 scopus 로고    scopus 로고
    • Tlr-4 deficiency selectively protects against obesity induced by diets high in saturated fat
    • Davis JE, Gabler NK, Walker-Daniels J, Spurlock ME. Tlr-4 deficiency selectively protects against obesity induced by diets high in saturated fat. Obesity (Silver Spring) 2008;16:1248-1255
    • (2008) Obesity (Silver Spring) , vol.16 , pp. 1248-1255
    • Davis, J.E.1    Gabler, N.K.2    Walker-Daniels, J.3    Spurlock, M.E.4
  • 30
    • 79751535591 scopus 로고    scopus 로고
    • Loss of function mutation in toll-like receptor-4 does not offer protection against obesity and insulin resistance induced by a diet high in trans fat in mice
    • Vijay-Kumar M, Aitken JD, Carvalho FA, Ziegler TR, Gewirtz AT, Ganji V. Loss of function mutation in Toll-like receptor-4 does not offer protection against obesity and insulin resistance induced by a diet high in trans fat in mice. J Inflamm (Lond) 2011;8:2
    • (2011) J Inflamm (Lond) , vol.8 , pp. 2
    • Vijay-Kumar, M.1    Aitken, J.D.2    Carvalho, F.A.3    Ziegler, T.R.4    Gewirtz, A.T.5    Ganji, V.6
  • 31
    • 34250169823 scopus 로고    scopus 로고
    • Toll-like receptor-4 mediates vascular inflammation and insulin resistance in diet-induced obesity
    • Kim F, Pham M, Luttrell I, et al. Toll-like receptor-4 mediates vascular inflammation and insulin resistance in diet-induced obesity. Circ Res 2007; 100:1589-1596
    • (2007) Circ Res , vol.100 , pp. 1589-1596
    • Kim, F.1    Pham, M.2    Luttrell, I.3
  • 32
    • 70350389389 scopus 로고    scopus 로고
    • Hematopoietic cell-specific deletion of toll-like receptor 4 ameliorates hepatic and adipose tissue insulin resistance in high-fat-fed mice
    • Saberi M, Woods N-B, de Luca C, et al. Hematopoietic cell-specific deletion of Toll-like receptor 4 ameliorates hepatic and adipose tissue insulin resistance in high-fat-fed mice. Cell Metab 2009;10:419-429
    • (2009) Cell Metab , vol.10 , pp. 419-429
    • Saberi, M.1    Woods, N.-B.2    De Luca, C.3
  • 33
    • 79955487247 scopus 로고    scopus 로고
    • Lipid-induced insulin resistance mediated by the proinflammatory receptor TLR4 requires saturated fatty acid-induced ceramide biosynthesis in mice
    • Holland WL, Bikman BT, Wang LP, et al. Lipid-induced insulin resistance mediated by the proinflammatory receptor TLR4 requires saturated fatty acid-induced ceramide biosynthesis in mice. J Clin Invest 2011;121:1858-1870
    • (2011) J Clin Invest , vol.121 , pp. 1858-1870
    • Holland, W.L.1    Bikman, B.T.2    Wang, L.P.3


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