메뉴 건너뛰기




Volumn 117, Issue 5, 2005, Pages 701-708

Macrophage migration and gene expression in response to tumor hypoxia

Author keywords

Angiogenesis; Hypoxia; Macrophage; Tumor; Tumor associated macrophages (TAMs)

Indexed keywords

CYTOKINE; ENZYME; MACROPHAGE INFLAMMATORY PROTEIN 1; MONOCYTE CHEMOTACTIC PROTEIN 1; MONOCYTE CHEMOTACTIC PROTEIN 2; RANTES;

EID: 27744472334     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/ijc.21422     Document Type: Short Survey
Times cited : (164)

References (97)
  • 1
    • 0037180757 scopus 로고    scopus 로고
    • Inflammation and cancer
    • Coussens LM, Werb Z. Inflammation and cancer. Nature 2002;420:860-7.
    • (2002) Nature , vol.420 , pp. 860-867
    • Coussens, L.M.1    Werb, Z.2
  • 2
    • 4143050218 scopus 로고    scopus 로고
    • The potential role of neutrophils in promoting the metastatic phenotype of tumors releasing interleukin-8
    • De Larco JE, Wuertz BRK, Furcht LT. The potential role of neutrophils in promoting the metastatic phenotype of tumors releasing interleukin-8. Clin Cancer Res 2004;10:4895-900.
    • (2004) Clin Cancer Res , vol.10 , pp. 4895-4900
    • De Larco, J.E.1    Wuertz, B.R.K.2    Furcht, L.T.3
  • 4
    • 0023836831 scopus 로고
    • Macrophages in human breast disease: A quantitative immunohistochemical study
    • Kelly PM, Davison RS, Bliss E, McGee JO. Macrophages in human breast disease: a quantitative immunohistochemical study. Br J Cancer 1988;57:174-7.
    • (1988) Br J Cancer , vol.57 , pp. 174-177
    • Kelly, P.M.1    Davison, R.S.2    Bliss, E.3    McGee, J.O.4
  • 5
    • 0034787977 scopus 로고    scopus 로고
    • Microenvironmental influence on macrophage regulation of angiogenesis in wounds and malignant tumors
    • Crowther M, Brown NJ, Bishop ET, Lewis CE. Microenvironmental influence on macrophage regulation of angiogenesis in wounds and malignant tumors. J Leukoc Biol 2001;70:478-90.
    • (2001) J Leukoc Biol , vol.70 , pp. 478-490
    • Crowther, M.1    Brown, N.J.2    Bishop, E.T.3    Lewis, C.E.4
  • 6
    • 0018080307 scopus 로고
    • Repopulation of γ-irradiated Lewis lung carcinoma by malignant cells and host macrophage progenitors
    • Stephens TC, Currie GA, Peacock JH. Repopulation of γ-irradiated Lewis lung carcinoma by malignant cells and host macrophage progenitors. Br J Cancer 1978;38:573-82.
    • (1978) Br J Cancer , vol.38 , pp. 573-582
    • Stephens, T.C.1    Currie, G.A.2    Peacock, J.H.3
  • 7
    • 4944244259 scopus 로고    scopus 로고
    • Mechanisms regulating the recruitment of macrophages into hypoxic areas of tumors and other ischemic tissues
    • Murdoch C, Giannoudis A, Lewis CE. Mechanisms regulating the recruitment of macrophages into hypoxic areas of tumors and other ischemic tissues. Blood 2004;104:2224-34.
    • (2004) Blood , vol.104 , pp. 2224-2234
    • Murdoch, C.1    Giannoudis, A.2    Lewis, C.E.3
  • 8
    • 0030944928 scopus 로고    scopus 로고
    • Quantitative assessment of the leukocyte infiltrate in ovarian cancer and its relationship to the expression of C-C chemokines
    • Negus RP, Stamp GW, Hadley J, Balkwill FR. Quantitative assessment of the leukocyte infiltrate in ovarian cancer and its relationship to the expression of C-C chemokines. Am J Pathol 1997;150:1723-34.
    • (1997) Am J Pathol , vol.150 , pp. 1723-1734
    • Negus, R.P.1    Stamp, G.W.2    Hadley, J.3    Balkwill, F.R.4
  • 9
  • 10
    • 0036554735 scopus 로고    scopus 로고
    • Analysis of chemokines and chemokine receptor expression in ovarian cancer ascites
    • Milliken D, Scotton C, Raju S, Balkwill F, Wilson J. Analysis of chemokines and chemokine receptor expression in ovarian cancer ascites. Clin Cancer Res 2002;8:1108-14.
    • (2002) Clin Cancer Res , vol.8 , pp. 1108-1114
    • Milliken, D.1    Scotton, C.2    Raju, S.3    Balkwill, F.4    Wilson, J.5
  • 11
    • 0038230415 scopus 로고    scopus 로고
    • The macrophage growth factor CSF-1 in mammary gland development and tumor progression
    • Lin EY, Gouon E, Nguyen AV, Pollard JW. The macrophage growth factor CSF-1 in mammary gland development and tumor progression. J Mammary Gland Biol Neoplasia 2002;7:147-62.
    • (2002) J Mammary Gland Biol Neoplasia , vol.7 , pp. 147-162
    • Lin, E.Y.1    Gouon, E.2    Nguyen, A.V.3    Pollard, J.W.4
  • 12
    • 0025688912 scopus 로고
    • Vascular permeability factor: A tumor-derived polypeptide that induces endothelial cell and monocyte procoagulant activity, and promotes monocyte migration
    • Clauss M, Gerlach M, Gerlach H, Brett J, Wang F, Familletti PC, Pan YC, Olander JV, Connolly DT, Stern D. Vascular permeability factor: a tumor-derived polypeptide that induces endothelial cell and monocyte procoagulant activity, and promotes monocyte migration. J Exp Med 1990;172:1535-45.
    • (1990) J Exp Med , vol.172 , pp. 1535-1545
    • Clauss, M.1    Gerlach, M.2    Gerlach, H.3    Brett, J.4    Wang, F.5    Familletti, P.C.6    Pan, Y.C.7    Olander, J.V.8    Connolly, D.T.9    Stern, D.10
  • 13
    • 0034021278 scopus 로고    scopus 로고
    • Macrophage infiltration is associated with VEGF and EGFR expression in breast cancer
    • Leek RD, Hunt NC, Landers RJ, Lewis CE, Royds JA, Harris AL. Macrophage infiltration is associated with VEGF and EGFR expression in breast cancer. J Pathol 2000;190:430-6.
    • (2000) J Pathol , vol.190 , pp. 430-436
    • Leek, R.D.1    Hunt, N.C.2    Landers, R.J.3    Lewis, C.E.4    Royds, J.A.5    Harris, A.L.6
  • 15
    • 0037467569 scopus 로고    scopus 로고
    • Endothelin-1: A multifunctional molecule in cancer
    • Grant K, Loizidou M, Taylor I. Endothelin-1: a multifunctional molecule in cancer. Br J Cancer 2003;88:163-6.
    • (2003) Br J Cancer , vol.88 , pp. 163-166
    • Grant, K.1    Loizidou, M.2    Taylor, I.3
  • 16
    • 2142662869 scopus 로고    scopus 로고
    • Infiltration of tumours by macrophages and dendritic cells: Tumour-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes
    • Mantovani A, Sozzani S, Locati M, Schioppa T, Saccani A, Allavena P, Sica A. Infiltration of tumours by macrophages and dendritic cells: tumour-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes. Novartis Found Symp 2004;256:137-45.
    • (2004) Novartis Found Symp , vol.256 , pp. 137-145
    • Mantovani, A.1    Sozzani, S.2    Locati, M.3    Schioppa, T.4    Saccani, A.5    Allavena, P.6    Sica, A.7
  • 17
    • 0033405294 scopus 로고    scopus 로고
    • The hypoxic cell: A target for selective cancer therapy-eighteenth Bruce F. Cain Memorial Award lecture
    • Brown JM. The hypoxic cell: a target for selective cancer therapy-eighteenth Bruce F. Cain Memorial Award lecture. Cancer Res 1999;59:5863-70.
    • (1999) Cancer Res , vol.59 , pp. 5863-5870
    • Brown, J.M.1
  • 18
    • 0034743861 scopus 로고    scopus 로고
    • Oxygen status of malignant tumors: Pathogenesis of hypoxia and significance for tumor therapy
    • Vaupel P, Kelleher DK, Hockel M. Oxygen status of malignant tumors: pathogenesis of hypoxia and significance for tumor therapy. Semin Oncol 2001;28:29-35.
    • (2001) Semin Oncol , vol.28 , pp. 29-35
    • Vaupel, P.1    Kelleher, D.K.2    Hockel, M.3
  • 19
    • 0029816609 scopus 로고    scopus 로고
    • Association of macrophage infiltration with angiogenesis and prognosis in invasive breast carcinoma
    • Leek RD, Lewis CE, Whitehouse R, Greenall M, Clarke J, Harris AL. Association of macrophage infiltration with angiogenesis and prognosis in invasive breast carcinoma. Cancer Res 1996;56:4625-9.
    • (1996) Cancer Res , vol.56 , pp. 4625-4629
    • Leek, R.D.1    Lewis, C.E.2    Whitehouse, R.3    Greenall, M.4    Clarke, J.5    Harris, A.L.6
  • 20
    • 0032867830 scopus 로고    scopus 로고
    • Tumor-associated macrophage infiltration in pulmonary adenocarcinoma: Association with angiogenesis and poor prognosis
    • Takanami I, Takeuchi K, Kodaira S. Tumor-associated macrophage infiltration in pulmonary adenocarcinoma: association with angiogenesis and poor prognosis. Oncology 1999;57:138-42.
    • (1999) Oncology , vol.57 , pp. 138-142
    • Takanami, I.1    Takeuchi, K.2    Kodaira, S.3
  • 21
    • 0034266661 scopus 로고    scopus 로고
    • Tumor associated macrophages in human prostate cancer: Relation to clinicopathological variables and survival
    • Lissbrant IF, Stattin P, Wikstrom P, Damber JE, Egevad L, Bergh A. Tumor associated macrophages in human prostate cancer: relation to clinicopathological variables and survival. Int J Oncol 2000;17:445-51.
    • (2000) Int J Oncol , vol.17 , pp. 445-451
    • Lissbrant, I.F.1    Stattin, P.2    Wikstrom, P.3    Damber, J.E.4    Egevad, L.5    Bergh, A.6
  • 22
    • 0033595619 scopus 로고    scopus 로고
    • Significance of tumour-associated macrophages, vascular endothelial growth factor and thrombospondin-1 expression for tumour angiogenesis and prognosis in endometrial carcinomas
    • Salvesen HB, Akslen LA. Significance of tumour-associated macrophages, vascular endothelial growth factor and thrombospondin-1 expression for tumour angiogenesis and prognosis in endometrial carcinomas. Int J Cancer 1999;84:538-43.
    • (1999) Int J Cancer , vol.84 , pp. 538-543
    • Salvesen, H.B.1    Akslen, L.A.2
  • 23
    • 0033067163 scopus 로고    scopus 로고
    • Necrosis correlates with high vascular density and focal macrophage infiltration in invasive carcinoma of the breast
    • Leek RD, Landers RJ, Harris AL, Lewis CE. Necrosis correlates with high vascular density and focal macrophage infiltration in invasive carcinoma of the breast. Br J Cancer 1999;79:991-5.
    • (1999) Br J Cancer , vol.79 , pp. 991-995
    • Leek, R.D.1    Landers, R.J.2    Harris, A.L.3    Lewis, C.E.4
  • 24
    • 0036190869 scopus 로고    scopus 로고
    • Hypoxia-induced, perinecrotic expression of endothelial Per-ARNT-Sim domain protein-1/hypoxia-inducible factor-2α correlates with tumor progression, vascularization, and focal macrophage infiltration in bladder cancer
    • Onita T, Ji PG, Xuan JW, Sakai H, Kanetake H, Maxwell PH, Fong GH, Gabril MY, Moussa M, Chin JL. Hypoxia-induced, perinecrotic expression of endothelial Per-ARNT-Sim domain protein-1/hypoxia-inducible factor-2α correlates with tumor progression, vascularization, and focal macrophage infiltration in bladder cancer. Clin Cancer Res 2002;8:471-80.
    • (2002) Clin Cancer Res , vol.8 , pp. 471-480
    • Onita, T.1    Ji, P.G.2    Xuan, J.W.3    Sakai, H.4    Kanetake, H.5    Maxwell, P.H.6    Fong, G.H.7    Gabril, M.Y.8    Moussa, M.9    Chin, J.L.10
  • 25
    • 0033780453 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor by macrophages is up-regulated in poorly vascularized areas of breast carcinomas
    • Lewis JS, Landers RJ, Underwood JC, Harris AL, Lewis CE. Expression of vascular endothelial growth factor by macrophages is up-regulated in poorly vascularized areas of breast carcinomas. J Pathol 2000;192:150-8.
    • (2000) J Pathol , vol.192 , pp. 150-158
    • Lewis, J.S.1    Landers, R.J.2    Underwood, J.C.3    Harris, A.L.4    Lewis, C.E.5
  • 26
    • 0036740130 scopus 로고    scopus 로고
    • Endothelin-2 is a macrophage chemoattractant: Implications for macrophage distribution in tumors
    • Grimshaw MJ, Wilson JL, Balkwill FR. Endothelin-2 is a macrophage chemoattractant: implications for macrophage distribution in tumors. Eur J Immunol 2002;32:2393-400.
    • (2002) Eur J Immunol , vol.32 , pp. 2393-2400
    • Grimshaw, M.J.1    Wilson, J.L.2    Balkwill, F.R.3
  • 28
    • 0028127621 scopus 로고
    • Activation of alveolar macrophages by native and synthetic collagen-like polypeptides
    • Laskin DL, Soltys RA, Berg RA, Riley DJ. Activation of alveolar macrophages by native and synthetic collagen-like polypeptides. Am J Respir Cell Mol Biol 1994;10:58-64.
    • (1994) Am J Respir Cell Mol Biol , vol.10 , pp. 58-64
    • Laskin, D.L.1    Soltys, R.A.2    Berg, R.A.3    Riley, D.J.4
  • 29
    • 0035101398 scopus 로고    scopus 로고
    • Inhibition of monocyte and macrophage chemotaxis by hypoxia and inflammation - A potential mechanism
    • Grimshaw MJ, Balkwill FR. Inhibition of monocyte and macrophage chemotaxis by hypoxia and inflammation-a potential mechanism. Eur J Immunol 2001;31:480-9.
    • (2001) Eur J Immunol , vol.31 , pp. 480-489
    • Grimshaw, M.J.1    Balkwill, F.R.2
  • 30
    • 0027358722 scopus 로고
    • MKP-1 (3CH134), an immediate early gene product, is a dual specificity phosphatase that dephosphorylates MAP kinase in vivo
    • Sun H, Charles CH, Lau LF, Tonks NK. MKP-1 (3CH134), an immediate early gene product, is a dual specificity phosphatase that dephosphorylates MAP kinase in vivo. Cell 1993;75:487-93.
    • (1993) Cell , vol.75 , pp. 487-493
    • Sun, H.1    Charles, C.H.2    Lau, L.F.3    Tonks, N.K.4
  • 31
    • 0030794511 scopus 로고    scopus 로고
    • Conditional expression of the mitogen-activated protein kinase (MAPK) phosphatase MKP-1 preferentially inhibits p38 MAPK and stress-activated protein kinase in U937 cells
    • Franklin CC, Kraft AS. Conditional expression of the mitogen-activated protein kinase (MAPK) phosphatase MKP-1 preferentially inhibits p38 MAPK and stress-activated protein kinase in U937 cells. J Biol Chem 1997;272:16917-23.
    • (1997) J Biol Chem , vol.272 , pp. 16917-16923
    • Franklin, C.C.1    Kraft, A.S.2
  • 32
    • 0035686902 scopus 로고    scopus 로고
    • Differential signaling for MCP-1-dependent integrin activation and chemotaxis
    • Ashida N, Arai H, Yamasaki M, Kita T. Differential signaling for MCP-1-dependent integrin activation and chemotaxis. Ann NY Acad Sci 2001;947:387-9.
    • (2001) Ann NY Acad Sci , vol.947 , pp. 387-389
    • Ashida, N.1    Arai, H.2    Yamasaki, M.3    Kita, T.4
  • 33
    • 0036232894 scopus 로고    scopus 로고
    • Leucocyte chemotaxis: Examination of mitogen-activated protein kinase and phosphoinositide 3-kinase activation by monocyte chemoattractant proteins-1, -2, -3 and -4
    • Wain JH, Kirby JA, Ali S. Leucocyte chemotaxis: examination of mitogen-activated protein kinase and phosphoinositide 3-kinase activation by monocyte chemoattractant proteins-1, -2, -3 and -4. Clin Exp Immunol 2002;127:436-44.
    • (2002) Clin Exp Immunol , vol.127 , pp. 436-444
    • Wain, J.H.1    Kirby, J.A.2    Ali, S.3
  • 35
    • 0141425768 scopus 로고    scopus 로고
    • Hypoxia-induced gene expression in human macrophages: Implications for ischemic tissues and hypoxia-regulated gene therapy
    • Burke B, Giannoudis A, Corke KP, Gill D, Wells M, Ziegler-Heitbrock L, Lewis CE. Hypoxia-induced gene expression in human macrophages: implications for ischemic tissues and hypoxia-regulated gene therapy. Am J Pathol 2003;163:1233-43.
    • (2003) Am J Pathol , vol.163 , pp. 1233-1243
    • Burke, B.1    Giannoudis, A.2    Corke, K.P.3    Gill, D.4    Wells, M.5    Ziegler-Heitbrock, L.6    Lewis, C.E.7
  • 37
    • 2942620525 scopus 로고    scopus 로고
    • Hypoxia inhibits the expression of the CCR5 chemokine receptor in macrophages
    • Bosco MC, Reffo G, Puppo M, Varesio L. Hypoxia inhibits the expression of the CCR5 chemokine receptor in macrophages. Cell Immunol 2004;228:1-7.
    • (2004) Cell Immunol , vol.228 , pp. 1-7
    • Bosco, M.C.1    Reffo, G.2    Puppo, M.3    Varesio, L.4
  • 38
    • 0031801052 scopus 로고    scopus 로고
    • Hypoxia down-regulates MCP-1 expression: Implications for macrophage distribution in tumors
    • Negus RP, Turner L, Burke F, Balkwill FR. Hypoxia down-regulates MCP-1 expression: implications for macrophage distribution in tumors. J Leukoc Biol 1998;63:758-65.
    • (1998) J Leukoc Biol , vol.63 , pp. 758-765
    • Negus, R.P.1    Turner, L.2    Burke, F.3    Balkwill, F.R.4
  • 40
    • 0035721955 scopus 로고    scopus 로고
    • Role of the matrix metalloproteinase and plasminogen activator-plasm in systems in angiogenesis
    • Pepper MS. Role of the matrix metalloproteinase and plasminogen activator-plasm in systems in angiogenesis. Arterioscler Thromb Vasc Biol 2001;21:1104-17.
    • (2001) Arterioscler Thromb Vasc Biol , vol.21 , pp. 1104-1117
    • Pepper, M.S.1
  • 44
    • 0033437175 scopus 로고    scopus 로고
    • Suppression of the reactive oxygen intermediates production of human macrophages by colorectal adenocarcinoma cell lines
    • Siegert A, Denkert C, Leclere A, Hauptmann S. Suppression of the reactive oxygen intermediates production of human macrophages by colorectal adenocarcinoma cell lines. Immunology 1999;98:551-6.
    • (1999) Immunology , vol.98 , pp. 551-556
    • Siegert, A.1    Denkert, C.2    Leclere, A.3    Hauptmann, S.4
  • 45
    • 0031709864 scopus 로고    scopus 로고
    • Tumor-induced immune dysfunction: The macrophage connection
    • Elgert KD, Alleva DG, Mullins DW. Tumor-induced immune dysfunction: the macrophage connection. J Leukoc Biol 1998;64:275-90.
    • (1998) J Leukoc Biol , vol.64 , pp. 275-290
    • Elgert, K.D.1    Alleva, D.G.2    Mullins, D.W.3
  • 46
    • 0035993208 scopus 로고    scopus 로고
    • Tumor-associated macrophages: A molecular perspective
    • Sica A, Saccani A, Mantovani A. Tumor-associated macrophages: a molecular perspective. Int Immunopharmacol 2002;2:1045-54.
    • (2002) Int Immunopharmacol , vol.2 , pp. 1045-1054
    • Sica, A.1    Saccani, A.2    Mantovani, A.3
  • 47
    • 0036187615 scopus 로고    scopus 로고
    • The role of tumour-associated macrophages in tumour progression: Implications for new anticancer therapies
    • Bingle L, Brown NJ, Lewis CE. The role of tumour-associated macrophages in tumour progression: implications for new anticancer therapies. J Pathol 2002;196:254-65.
    • (2002) J Pathol , vol.196 , pp. 254-265
    • Bingle, L.1    Brown, N.J.2    Lewis, C.E.3
  • 48
    • 0347123433 scopus 로고    scopus 로고
    • Tumour-educated macrophages promote tumour progression and metastasis
    • Pollard JW. Tumour-educated macrophages promote tumour progression and metastasis. Nat Rev Cancer 2004;4:71-8.
    • (2004) Nat Rev Cancer , vol.4 , pp. 71-78
    • Pollard, J.W.1
  • 49
    • 0036007293 scopus 로고    scopus 로고
    • Expression of HIF-1α by human macrophages: Implications for the use of macrophages in hypoxia-regulated cancer gene therapy
    • Burke B, Tang N, Corke KP, Tazzyman D, Ameri K, Wells M, Lewis CE. Expression of HIF-1α by human macrophages: implications for the use of macrophages in hypoxia-regulated cancer gene therapy. J Pathol 2002;196:204-12.
    • (2002) J Pathol , vol.196 , pp. 204-212
    • Burke, B.1    Tang, N.2    Corke, K.P.3    Tazzyman, D.4    Ameri, K.5    Wells, M.6    Lewis, C.E.7
  • 50
    • 0033870281 scopus 로고    scopus 로고
    • The expression and distribution of the hypoxia-inducible factors HIF-1α and HIF-2α in normal human tissues, cancers, and tumor-associated macrophages
    • Talks KL, Turley H, Gatter KC, Maxwell PH, Pugh CW, Ratcliffe PJ, Harris AL. The expression and distribution of the hypoxia-inducible factors HIF-1α and HIF-2α in normal human tissues, cancers, and tumor-associated macrophages. Am J Pathol 2000;157:411-21.
    • (2000) Am J Pathol , vol.157 , pp. 411-421
    • Talks, K.L.1    Turley, H.2    Gatter, K.C.3    Maxwell, P.H.4    Pugh, C.W.5    Ratcliffe, P.J.6    Harris, A.L.7
  • 51
    • 0142166332 scopus 로고    scopus 로고
    • Targeting HIF-1 for cancer therapy
    • Semenza GL. Targeting HIF-1 for cancer therapy. Nat Rev Cancer 2003;3:721-32.
    • (2003) Nat Rev Cancer , vol.3 , pp. 721-732
    • Semenza, G.L.1
  • 52
    • 0036359548 scopus 로고    scopus 로고
    • Hypoxia - A key regulatory factor in tumour growth
    • Harris AL. Hypoxia - a key regulatory factor in tumour growth. Nat Rev Cancer 2002;2:38-47.
    • (2002) Nat Rev Cancer , vol.2 , pp. 38-47
    • Harris, A.L.1
  • 54
    • 0036493984 scopus 로고    scopus 로고
    • Relation of hypoxia-inducible factor-2α (HIF-2α) expression in tumor-infiltrative macrophages to tumor angiogenesis and the oxidative thymidine phosphorylase pathway in human breast cancer
    • Leek RD, Talks KL, Pezzella F, Turley H, Campo L, Brown NS, Bicknell R, Taylor M, Gatter KC, Harris AL. Relation of hypoxia-inducible factor-2α (HIF-2α) expression in tumor-infiltrative macrophages to tumor angiogenesis and the oxidative thymidine phosphorylase pathway in human breast cancer. Cancer Res 2002;62:1326-9.
    • (2002) Cancer Res , vol.62 , pp. 1326-1329
    • Leek, R.D.1    Talks, K.L.2    Pezzella, F.3    Turley, H.4    Campo, L.5    Brown, N.S.6    Bicknell, R.7    Taylor, M.8    Gatter, K.C.9    Harris, A.L.10
  • 55
    • 0038788826 scopus 로고    scopus 로고
    • Hypoxia-induced gene expression occurs solely through the action of hypoxia-inducible factor 1α (HIF-1α): Role of cytoplasmic trapping of HIF-2α
    • Park SK, Dadak AM, Haase VH, Fontana L, Giaccia AJ, Johnson RS. Hypoxia-induced gene expression occurs solely through the action of hypoxia-inducible factor 1α (HIF-1α): role of cytoplasmic trapping of HIF-2α. Mol Cell Biol 2003;23:4959-71.
    • (2003) Mol Cell Biol , vol.23 , pp. 4959-4971
    • Park, S.K.1    Dadak, A.M.2    Haase, V.H.3    Fontana, L.4    Giaccia, A.J.5    Johnson, R.S.6
  • 58
    • 0141988698 scopus 로고    scopus 로고
    • Predominant role of hypoxia-inducible transcription factor (Hif)-1α versus Hif-2α in regulation of the transcriptional response to hypoxia
    • Erratum, 63:6562
    • Sowter HM, Raval RR, Moore JW, Ratcliffe PJ, Harris AL. Predominant role of hypoxia-inducible transcription factor (Hif)-1α versus Hif-2α in regulation of the transcriptional response to hypoxia. Cancer Res 2003;63:6130-4. Erratum, 63:6562.
    • (2003) Cancer Res , vol.63 , pp. 6130-6134
    • Sowter, H.M.1    Raval, R.R.2    Moore, J.W.3    Ratcliffe, P.J.4    Harris, A.L.5
  • 59
    • 0345491599 scopus 로고    scopus 로고
    • Differential roles of hypoxia-inducible factor 1α (HIF-1α) and HIF-2α in hypoxic gene regulation
    • Hu CJ, Wang LY, Chodosh LA, Keith B, Simon MC. Differential roles of hypoxia-inducible factor 1α (HIF-1α) and HIF-2α in hypoxic gene regulation. Mol Cell Biol 2003;23:9361-74.
    • (2003) Mol Cell Biol , vol.23 , pp. 9361-9374
    • Hu, C.J.1    Wang, L.Y.2    Chodosh, L.A.3    Keith, B.4    Simon, M.C.5
  • 60
    • 0034661990 scopus 로고    scopus 로고
    • Role of oxidants in NF-κB activation and TNF-α gene transcription induced by hypoxia and endotoxin
    • Chandel NS, Trzyna WC, McClintock DS, Schumacker PT. Role of oxidants in NF-κB activation and TNF-α gene transcription induced by hypoxia and endotoxin. J Immunol 2000;165:1013-21.
    • (2000) J Immunol , vol.165 , pp. 1013-1021
    • Chandel, N.S.1    Trzyna, W.C.2    McClintock, D.S.3    Schumacker, P.T.4
  • 61
    • 9444252869 scopus 로고    scopus 로고
    • Hypoxia induces macrophage inflammatory protein-2 (MIP-2) gene expression in murine macrophages via NF-κB: The prominent role of p42/p44 and PI3 kinase pathways
    • Zampetaki A, Mitsialis SA, Pfeilschifter J, Kourembanas S. Hypoxia induces macrophage inflammatory protein-2 (MIP-2) gene expression in murine macrophages via NF-κB: the prominent role of p42/p44 and PI3 kinase pathways. FASEB J 2004;18:U808-27.
    • (2004) FASEB J , vol.18
    • Zampetaki, A.1    Mitsialis, S.A.2    Pfeilschifter, J.3    Kourembanas, S.4
  • 62
    • 0034650833 scopus 로고    scopus 로고
    • Autocrine production of IL-10 mediates defective IL-12 production and NF-κB activation in tumor-associated macrophages
    • Sica A, Saccani A, Bottazzi B, Polentarutti N, Vecchi A, Van Damme J, Mantovani A. Autocrine production of IL-10 mediates defective IL-12 production and NF-κB activation in tumor-associated macrophages. J Immunol 2000;164:762-7.
    • (2000) J Immunol , vol.164 , pp. 762-767
    • Sica, A.1    Saccani, A.2    Bottazzi, B.3    Polentarutti, N.4    Vecchi, A.5    Van Damme, J.6    Mantovani, A.7
  • 63
    • 14644443546 scopus 로고    scopus 로고
    • Interleukin-10 (IL-10) mediated suppression of IL-12 production in RAW 264.7 cells also involves c-rel transcription factor
    • Rahim SS, Khan N, Boddupalli CS, Hasnain SE, Mukhopadhyay S. Interleukin-10 (IL-10) mediated suppression of IL-12 production in RAW 264.7 cells also involves c-rel transcription factor. Immunology 2005;114:313-21.
    • (2005) Immunology , vol.114 , pp. 313-321
    • Rahim, S.S.1    Khan, N.2    Boddupalli, C.S.3    Hasnain, S.E.4    Mukhopadhyay, S.5
  • 64
    • 0032801526 scopus 로고    scopus 로고
    • Comparisons among pimonidazole binding, oxygen electrode measurements, and radiation response in C3H mouse tumors
    • Raleigh JA, Chou SC, Arteel GE, Horsman MR. Comparisons among pimonidazole binding, oxygen electrode measurements, and radiation response in C3H mouse tumors. Radiat Res 1999;151:580-9.
    • (1999) Radiat Res , vol.151 , pp. 580-589
    • Raleigh, J.A.1    Chou, S.C.2    Arteel, G.E.3    Horsman, M.R.4
  • 65
    • 0028784382 scopus 로고
    • Identification of hypoxia in cells and tissues of epigastric 9L rat glioma using EF5 [2-(2-nitro-1H-imidazol-1-yl)-N-(2,2,3,3,3-pentafluoropropyl) acetamide]
    • Evans SM, Joiner B, Jenkins WT, Laughlin KM, Lord EM, Koch CJ. Identification of hypoxia in cells and tissues of epigastric 9L rat glioma using EF5 [2-(2-nitro-1H-imidazol-1-yl)-N-(2,2,3,3,3-pentafluoropropyl) acetamide]. Br J Cancer 1995;72:875-82.
    • (1995) Br J Cancer , vol.72 , pp. 875-882
    • Evans, S.M.1    Joiner, B.2    Jenkins, W.T.3    Laughlin, K.M.4    Lord, E.M.5    Koch, C.J.6
  • 66
    • 0031839355 scopus 로고    scopus 로고
    • Regulation of macrophage production of vascular endothelial growth factor (VEGF) by hypoxia and transforming growth factor β-1
    • Harmey JH, Dimitriadis E, Kay E, Redmond HP, Bouchier-Hayes D. Regulation of macrophage production of vascular endothelial growth factor (VEGF) by hypoxia and transforming growth factor β-1. Ann Surg Oncol 1998;5:271-8.
    • (1998) Ann Surg Oncol , vol.5 , pp. 271-278
    • Harmey, J.H.1    Dimitriadis, E.2    Kay, E.3    Redmond, H.P.4    Bouchier-Hayes, D.5
  • 67
    • 0031039243 scopus 로고    scopus 로고
    • The biology of vascular endothelial growth factor
    • Ferrara N, Davis S, The biology of vascular endothelial growth factor. Endocr Rev 1997;18:4-25.
    • (1997) Endocr Rev , vol.18 , pp. 4-25
    • Ferrara, N.1    Davis, S.2
  • 68
    • 0029070920 scopus 로고
    • Hypoxia-mediated induction of acidic/basic fibroblast growth factor and platelet-derived growth factor in mononuclear phagocytes stimulates growth of hypoxic endothelial cells
    • Kuwabara K, Ogawa S, Matsumoto M, Koga S, Clauss M, Pinsky DJ, Lyn P, Leavy J, Witte L, Joseph-Silverstein J. Hypoxia-mediated induction of acidic/basic fibroblast growth factor and platelet-derived growth factor in mononuclear phagocytes stimulates growth of hypoxic endothelial cells. Proc Natl Acad Sci USA 1995;92:4606-10.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 4606-4610
    • Kuwabara, K.1    Ogawa, S.2    Matsumoto, M.3    Koga, S.4    Clauss, M.5    Pinsky, D.J.6    Lyn, P.7    Leavy, J.8    Witte, L.9    Joseph-Silverstein, J.10
  • 69
    • 0028884216 scopus 로고
    • Growth factors in breast cancer
    • Dickson RB, Lippman ME. Growth factors in breast cancer. Endocr Rev 1995;16:559-89.
    • (1995) Endocr Rev , vol.16 , pp. 559-589
    • Dickson, R.B.1    Lippman, M.E.2
  • 71
    • 0030061278 scopus 로고    scopus 로고
    • Matrilysin: An epithelial matrix metalloproteinase with potentially novel functions
    • Wilson CL, Matrisian LM. Matrilysin: an epithelial matrix metalloproteinase with potentially novel functions. Int J Biochem Cell Biol 1996;28:123-36.
    • (1996) Int J Biochem Cell Biol , vol.28 , pp. 123-136
    • Wilson, C.L.1    Matrisian, L.M.2
  • 72
    • 0036014874 scopus 로고    scopus 로고
    • Matrix metalloproteinase inhibitors: Do they have a place in anticancer therapy?
    • Rudek MA, Venitz J, Figg WD. Matrix metalloproteinase inhibitors: do they have a place in anticancer therapy? Pharmacotherapy 2002;22:705-20.
    • (2002) Pharmacotherapy , vol.22 , pp. 705-720
    • Rudek, M.A.1    Venitz, J.2    Figg, W.D.3
  • 73
    • 0031983911 scopus 로고    scopus 로고
    • Influence of hypoxia and glucose deprivation on tumour necrosis factor-α and granulocyte-macrophage colony-stimulating factor expression in human cultured monocytes
    • Guida E, Stewart A. Influence of hypoxia and glucose deprivation on tumour necrosis factor-α and granulocyte-macrophage colony-stimulating factor expression in human cultured monocytes. Cell Physiol Biochem 1998;8:75-88.
    • (1998) Cell Physiol Biochem , vol.8 , pp. 75-88
    • Guida, E.1    Stewart, A.2
  • 74
    • 0027244544 scopus 로고
    • Hypoxia induces a human macrophage cell line to release tumor necrosis factor-α and its soluble receptors in vitro
    • Scannell G, Waxman K, Kami GJ, Ioli G, Gatanaga T, Yamamoto R, Granger GA. Hypoxia induces a human macrophage cell line to release tumor necrosis factor-α and its soluble receptors in vitro. J Surg Res 1993;54:281-5.
    • (1993) J Surg Res , vol.54 , pp. 281-285
    • Scannell, G.1    Waxman, K.2    Kami, G.J.3    Ioli, G.4    Gatanaga, T.5    Yamamoto, R.6    Granger, G.A.7
  • 75
    • 0030077687 scopus 로고    scopus 로고
    • Effect of hypoxia on release of IL-1 and TNF by human alveolar macrophages
    • Hempel SL, Monick MM, Hunninghake GW. Effect of hypoxia on release of IL-1 and TNF by human alveolar macrophages. Am J Respir Cell Mol Biol 1996;14:170-6.
    • (1996) Am J Respir Cell Mol Biol , vol.14 , pp. 170-176
    • Hempel, S.L.1    Monick, M.M.2    Hunninghake, G.W.3
  • 76
    • 0031009807 scopus 로고    scopus 로고
    • Involvement of interleukin-8, vascular endothelial growth factor, and basic fibroblast growth factor in tumor necrosis factor α-dependent angiogenesis
    • Yoshida S, Ono M, Shono T, Izumi H, Ishibashi T, Suzuki H, Kuwano M. Involvement of interleukin-8, vascular endothelial growth factor, and basic fibroblast growth factor in tumor necrosis factor α-dependent angiogenesis. Mol Cell Biol 1997;17:4015-23.
    • (1997) Mol Cell Biol , vol.17 , pp. 4015-4023
    • Yoshida, S.1    Ono, M.2    Shono, T.3    Izumi, H.4    Ishibashi, T.5    Suzuki, H.6    Kuwano, M.7
  • 77
    • 85061108779 scopus 로고    scopus 로고
    • Interleukin-1α (IL-1α) promotes angiogenesis in vivo via VEGFR-2 pathway by inducing inflammatory cell VEGF synthesis and secretion
    • Salven P, Hattori K, Heissig B, Rafii S. Interleukin-1α (IL-1α) promotes angiogenesis in vivo via VEGFR-2 pathway by inducing inflammatory cell VEGF synthesis and secretion. FASEB J 2002;16:U25-37.
    • (2002) FASEB J , vol.16
    • Salven, P.1    Hattori, K.2    Heissig, B.3    Rafii, S.4
  • 78
    • 0033756658 scopus 로고    scopus 로고
    • Tumor growth-promoting properties of macrophage migration inhibitory factor (MIF)
    • Mitchell RA, Bucala R. Tumor growth-promoting properties of macrophage migration inhibitory factor (MIF). Semin Cancer Biol 2000;10:359-66.
    • (2000) Semin Cancer Biol , vol.10 , pp. 359-366
    • Mitchell, R.A.1    Bucala, R.2
  • 80
    • 0035174962 scopus 로고    scopus 로고
    • The regulation of interleukin-8 by hypoxia in human macrophages - A potential role in the pathogenesis of the acute respiratory distress syndrome (ARDS)
    • Hirani N, Antonicelli F, Strieter RM, Wiesener MS, Haslett C, Donnelly SC. The regulation of interleukin-8 by hypoxia in human macrophages - a potential role in the pathogenesis of the acute respiratory distress syndrome (ARDS). Mol Med 2001;7:685-97.
    • (2001) Mol Med , vol.7 , pp. 685-697
    • Hirani, N.1    Antonicelli, F.2    Strieter, R.M.3    Wiesener, M.S.4    Haslett, C.5    Donnelly, S.C.6
  • 82
    • 0030967081 scopus 로고    scopus 로고
    • Chemokines induce migrational responses in human breast carcinoma cell lines
    • Youngs SJ, Ali SA, Taub DD, Rees RC. Chemokines induce migrational responses in human breast carcinoma cell lines. Int J Cancer 1997;71:257-66.
    • (1997) Int J Cancer , vol.71 , pp. 257-266
    • Youngs, S.J.1    Ali, S.A.2    Taub, D.D.3    Rees, R.C.4
  • 85
    • 0141828145 scopus 로고    scopus 로고
    • Chemokine receptor CXCR4 downregulated by von Hippel-Lindau tumour suppressor pVHL
    • Staller P, Sulitkova J, Lisztwan J, Moch H, Oakeley EJ, Krek W. Chemokine receptor CXCR4 downregulated by von Hippel-Lindau tumour suppressor pVHL. Nature 2003;425:307-11.
    • (2003) Nature , vol.425 , pp. 307-311
    • Staller, P.1    Sulitkova, J.2    Lisztwan, J.3    Moch, H.4    Oakeley, E.J.5    Krek, W.6
  • 87
    • 2342591450 scopus 로고    scopus 로고
    • The significance of cancer cell expression of the chemokine receptor CXCR4
    • Balkwill F. The significance of cancer cell expression of the chemokine receptor CXCR4. Semin Cancer Biol 2004;14:171-9.
    • (2004) Semin Cancer Biol , vol.14 , pp. 171-179
    • Balkwill, F.1
  • 91
    • 0037089405 scopus 로고    scopus 로고
    • Regulation of endothelial cell branching morphogenesis by endogenous chemokine stromal-derived factor-1
    • Salvucci O, Yao L, Villalba S, Sajewicz A, Pittaluga S, Tosato G. Regulation of endothelial cell branching morphogenesis by endogenous chemokine stromal-derived factor-1. Blood 2002;99:2703-11.
    • (2002) Blood , vol.99 , pp. 2703-2711
    • Salvucci, O.1    Yao, L.2    Villalba, S.3    Sajewicz, A.4    Pittaluga, S.5    Tosato, G.6
  • 93
    • 0036440486 scopus 로고    scopus 로고
    • Role of cyclooxygenase-2 in breast cancer
    • Singh B, Lucci A. Role of cyclooxygenase-2 in breast cancer. J Surg Res 2002;108:173-9.
    • (2002) J Surg Res , vol.108 , pp. 173-179
    • Singh, B.1    Lucci, A.2
  • 95
    • 0034936994 scopus 로고    scopus 로고
    • Expression of hypoxia-inducible factor 1α by macrophages in the rheumatoid synovium: Implications for targeting of therapeutic genes to the inflamed joint
    • Hollander AP, Corke KP, Freemont AJ, Lewis CE. Expression of hypoxia-inducible factor 1α by macrophages in the rheumatoid synovium: implications for targeting of therapeutic genes to the inflamed joint. Arthritis Rheum 2001;44:1540-4.
    • (2001) Arthritis Rheum , vol.44 , pp. 1540-1544
    • Hollander, A.P.1    Corke, K.P.2    Freemont, A.J.3    Lewis, C.E.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.