-
1
-
-
0024509701
-
Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome
-
Q.L. Choo, G. Kuo, A.J. Weiner, L.R. Overby, D.W. Bradley, and M. Houghton Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome Science 244 1989 359 362
-
(1989)
Science
, vol.244
, pp. 359-362
-
-
Choo, Q.L.1
Kuo, G.2
Weiner, A.J.3
Overby, L.R.4
Bradley, D.W.5
Houghton, M.6
-
2
-
-
0030864915
-
Transmission of hepatitis C by intrahepatic inoculation with transcribed RNA
-
A.A. Kolykhalov, E.V. Agapov, K.J. Blight, K. Mihalik, S.M. Feinstone, and C.M. Rice Transmission of hepatitis C by intrahepatic inoculation with transcribed RNA Science 277 1997 570 574
-
(1997)
Science
, vol.277
, pp. 570-574
-
-
Kolykhalov, A.A.1
Agapov, E.V.2
Blight, K.J.3
Mihalik, K.4
Feinstone, S.M.5
Rice, C.M.6
-
3
-
-
2542530063
-
A critical role for the chimpanzee model in the study of hepatitis C
-
J. Bukh A critical role for the chimpanzee model in the study of hepatitis C Hepatology 39 2004 1469 1475
-
(2004)
Hepatology
, vol.39
, pp. 1469-1475
-
-
Bukh, J.1
-
4
-
-
79953314182
-
HCV animal models: A journey of more than 30 years
-
P. Meuleman, and G. Leroux-Roels HCV animal models: a journey of more than 30 years Viruses 1 2009 222 240
-
(2009)
Viruses
, vol.1
, pp. 222-240
-
-
Meuleman, P.1
Leroux-Roels, G.2
-
5
-
-
84860287115
-
Animal models for the study of hepatitis C virus infection and related liver disease
-
J. Bukh Animal models for the study of hepatitis C virus infection and related liver disease Gastroenterology 142 2012 e1273
-
(2012)
Gastroenterology
, vol.142
, pp. 1273
-
-
Bukh, J.1
-
6
-
-
0345188811
-
Replication of subgenomic hepatitis C virus RNAs in a hepatoma cell line
-
V. Lohmann, F. Korner, J. Koch, U. Herian, L. Theilmann, and R. Bartenschlager Replication of subgenomic hepatitis C virus RNAs in a hepatoma cell line Science 285 1999 110 113
-
(1999)
Science
, vol.285
, pp. 110-113
-
-
Lohmann, V.1
Korner, F.2
Koch, J.3
Herian, U.4
Theilmann, L.5
Bartenschlager, R.6
-
7
-
-
0034623816
-
Efficient initiation of HCV RNA replication in cell culture
-
K.J. Blight, A.A. Kolykhalov, and C.M. Rice Efficient initiation of HCV RNA replication in cell culture Science 290 2000 1972 1974
-
(2000)
Science
, vol.290
, pp. 1972-1974
-
-
Blight, K.J.1
Kolykhalov, A.A.2
Rice, C.M.3
-
8
-
-
0037687422
-
Regulation of interferon regulatory factor-3 by the hepatitis C virus serine protease
-
E. Foy, K. Li, C. Wang, R. Sumpter Jr., M. Ikeda, and S.M. Lemon Regulation of interferon regulatory factor-3 by the hepatitis C virus serine protease Science 300 2003 1145 1148
-
(2003)
Science
, vol.300
, pp. 1145-1148
-
-
Foy, E.1
Li, K.2
Wang, C.3
Sumpter, R.4
Ikeda, M.5
Lemon, S.M.6
-
9
-
-
27144440476
-
Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus
-
E. Meylan, J. Curran, K. Hofmann, D. Moradpour, M. Binder, and R. Bartenschlager Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus Nature 437 2005 1167 1172
-
(2005)
Nature
, vol.437
, pp. 1167-1172
-
-
Meylan, E.1
Curran, J.2
Hofmann, K.3
Moradpour, D.4
Binder, M.5
Bartenschlager, R.6
-
10
-
-
68949105585
-
Nonstructural 3/4A protease of hepatitis C virus activates epithelial growth factor-induced signal transduction by cleavage of the T-cell protein tyrosine phosphatase
-
E.D. Brenndorfer, J. Karthe, L. Frelin, P. Cebula, A. Erhardt, and J. Schulte am Esch Nonstructural 3/4A protease of hepatitis C virus activates epithelial growth factor-induced signal transduction by cleavage of the T-cell protein tyrosine phosphatase Hepatology 49 2009 1810 1820
-
(2009)
Hepatology
, vol.49
, pp. 1810-1820
-
-
Brenndorfer, E.D.1
Karthe, J.2
Frelin, L.3
Cebula, P.4
Erhardt, A.5
Schulte Am Esch, J.6
-
11
-
-
0032737567
-
Hepatitis C virus-like particles synthesized in insect cells as a potential vaccine candidate
-
T.F. Baumert, J. Vergalla, J. Satoi, M. Thomson, M. Lechmann, and D. Herion Hepatitis C virus-like particles synthesized in insect cells as a potential vaccine candidate Gastroenterology 117 1999 1397 1407
-
(1999)
Gastroenterology
, vol.117
, pp. 1397-1407
-
-
Baumert, T.F.1
Vergalla, J.2
Satoi, J.3
Thomson, M.4
Lechmann, M.5
Herion, D.6
-
12
-
-
0037416146
-
Infectious hepatitis C virus pseudo-particles containing functional E1-E2 envelope protein complexes
-
B. Bartosch, J. Dubuisson, and F.L. Cosset Infectious hepatitis C virus pseudo-particles containing functional E1-E2 envelope protein complexes J Exp Med 197 2003 633 642
-
(2003)
J Exp Med
, vol.197
, pp. 633-642
-
-
Bartosch, B.1
Dubuisson, J.2
Cosset, F.L.3
-
13
-
-
0038471344
-
Hepatitis C virus glycoproteins mediate pH-dependent cell entry of pseudotyped retroviral particles
-
M. Hsu, J. Zhang, M. Flint, C. Logvinoff, C. Cheng-Mayer, and C.M. Rice Hepatitis C virus glycoproteins mediate pH-dependent cell entry of pseudotyped retroviral particles Proc Natl Acad Sci U S A 100 2003 7271 7276
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 7271-7276
-
-
Hsu, M.1
Zhang, J.2
Flint, M.3
Logvinoff, C.4
Cheng-Mayer, C.5
Rice, C.M.6
-
14
-
-
22544470874
-
Production of infectious hepatitis C virus in tissue culture from a cloned viral genome
-
T. Wakita, T. Pietschmann, T. Kato, T. Date, M. Miyamoto, and Z. Zhao Production of infectious hepatitis C virus in tissue culture from a cloned viral genome Nat Med 11 2005 791 796
-
(2005)
Nat Med
, vol.11
, pp. 791-796
-
-
Wakita, T.1
Pietschmann, T.2
Kato, T.3
Date, T.4
Miyamoto, M.5
Zhao, Z.6
-
15
-
-
21544440397
-
Robust hepatitis C virus infection in vitro
-
J. Zhong, P. Gastaminza, G. Cheng, S. Kapadia, T. Kato, and D.R. Burton Robust hepatitis C virus infection in vitro Proc Natl Acad Sci U S A 102 2005 9294 9299
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 9294-9299
-
-
Zhong, J.1
Gastaminza, P.2
Cheng, G.3
Kapadia, S.4
Kato, T.5
Burton, D.R.6
-
16
-
-
23044437222
-
Complete replication of hepatitis C virus in cell culture
-
B.D. Lindenbach, M.J. Evans, A.J. Syder, B. Wolk, T.L. Tellinghuisen, and C.C. Liu Complete replication of hepatitis C virus in cell culture Science 309 2005 623 626
-
(2005)
Science
, vol.309
, pp. 623-626
-
-
Lindenbach, B.D.1
Evans, M.J.2
Syder, A.J.3
Wolk, B.4
Tellinghuisen, T.L.5
Liu, C.C.6
-
17
-
-
84879420038
-
The molecular and structural basis of advanced antiviral therapy for hepatitis C virus infection
-
R. Bartenschlager, V. Lohmann, and F. Penin The molecular and structural basis of advanced antiviral therapy for hepatitis C virus infection Nat Rev Microbiol 11 2013 482 496
-
(2013)
Nat Rev Microbiol
, vol.11
, pp. 482-496
-
-
Bartenschlager, R.1
Lohmann, V.2
Penin, F.3
-
18
-
-
79251561245
-
Protease inhibitor-resistant hepatitis C virus mutants with reduced fitness from impaired production of infectious virus
-
T. Shimakami, C. Welsch, D. Yamane, D.R. McGivern, M. Yi, and S. Zeuzem Protease inhibitor-resistant hepatitis C virus mutants with reduced fitness from impaired production of infectious virus Gastroenterology 140 2011 667 675
-
(2011)
Gastroenterology
, vol.140
, pp. 667-675
-
-
Shimakami, T.1
Welsch, C.2
Yamane, D.3
McGivern, D.R.4
Yi, M.5
Zeuzem, S.6
-
19
-
-
84860817692
-
Robust full-length hepatitis C virus genotype 2a and 2b infectious cultures using mutations identified by a systematic approach applicable to patient strains
-
Y.P. Li, S. Ramirez, J.M. Gottwein, T.K. Scheel, L. Mikkelsen, and R.H. Purcell Robust full-length hepatitis C virus genotype 2a and 2b infectious cultures using mutations identified by a systematic approach applicable to patient strains Proc Natl Acad Sci U S A 109 2012 E1101 E1110
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 1101-E1110
-
-
Li, Y.P.1
Ramirez, S.2
Gottwein, J.M.3
Scheel, T.K.4
Mikkelsen, L.5
Purcell, R.H.6
-
20
-
-
84870372937
-
Highly efficient full-length hepatitis C virus genotype 1 (strain TN) infectious culture system
-
Y.P. Li, S. Ramirez, S.B. Jensen, R.H. Purcell, J.M. Gottwein, and J. Bukh Highly efficient full-length hepatitis C virus genotype 1 (strain TN) infectious culture system Proc Natl Acad Sci U S A 109 2012 19757 19762
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 19757-19762
-
-
Li, Y.P.1
Ramirez, S.2
Jensen, S.B.3
Purcell, R.H.4
Gottwein, J.M.5
Bukh, J.6
-
21
-
-
84867398704
-
Novel cell culture-adapted genotype 2a hepatitis C virus infectious clone
-
T. Date, T. Kato, J. Kato, H. Takahashi, K. Morikawa, and D. Akazawa Novel cell culture-adapted genotype 2a hepatitis C virus infectious clone J Virol 86 2012 10805 10820
-
(2012)
J Virol
, vol.86
, pp. 10805-10820
-
-
Date, T.1
Kato, T.2
Kato, J.3
Takahashi, H.4
Morikawa, K.5
Akazawa, D.6
-
22
-
-
84893053264
-
Highly efficient infectious cell culture of three hepatitis C virus genotype 2b strains and sensitivity to lead protease, nonstructural protein 5A, and polymerase inhibitors
-
S. Ramirez, Y.P. Li, S.B. Jensen, J. Pedersen, J.M. Gottwein, and J. Bukh Highly efficient infectious cell culture of three hepatitis C virus genotype 2b strains and sensitivity to lead protease, nonstructural protein 5A, and polymerase inhibitors Hepatology 59 2014 395 407
-
(2014)
Hepatology
, vol.59
, pp. 395-407
-
-
Ramirez, S.1
Li, Y.P.2
Jensen, S.B.3
Pedersen, J.4
Gottwein, J.M.5
Bukh, J.6
-
24
-
-
45749124737
-
Cutting the gordian knot-development and biological relevance of hepatitis C virus cell culture systems
-
J.M. Gottwein, and J. Bukh Cutting the gordian knot-development and biological relevance of hepatitis C virus cell culture systems Adv Virus Res 71 2008 51 133
-
(2008)
Adv Virus Res
, vol.71
, pp. 51-133
-
-
Gottwein, J.M.1
Bukh, J.2
-
25
-
-
34250699025
-
Gene expression profiling and differentiation assessment in primary human hepatocyte cultures, established hepatoma cell lines, and human liver tissues
-
K.M. Olsavsky, J.L. Page, M.C. Johnson, H. Zarbl, S.C. Strom, and C.J. Omiecinski Gene expression profiling and differentiation assessment in primary human hepatocyte cultures, established hepatoma cell lines, and human liver tissues Toxicol Appl Pharmacol 222 2007 42 56
-
(2007)
Toxicol Appl Pharmacol
, vol.222
, pp. 42-56
-
-
Olsavsky, K.M.1
Page, J.L.2
Johnson, M.C.3
Zarbl, H.4
Strom, S.C.5
Omiecinski, C.J.6
-
26
-
-
1842427904
-
The maintenance and generation of membrane polarity in hepatocytes
-
L. Wang, and J.L. Boyer The maintenance and generation of membrane polarity in hepatocytes Hepatology 39 2004 892 899
-
(2004)
Hepatology
, vol.39
, pp. 892-899
-
-
Wang, L.1
Boyer, J.L.2
-
27
-
-
77958051586
-
Advances and challenges in studying hepatitis C virus in its native environment
-
T. Sheahan, C.T. Jones, and A. Ploss Advances and challenges in studying hepatitis C virus in its native environment Expert Rev Gastroenterol Hepatol 4 2010 541 550
-
(2010)
Expert Rev Gastroenterol Hepatol
, vol.4
, pp. 541-550
-
-
Sheahan, T.1
Jones, C.T.2
Ploss, A.3
-
28
-
-
77957341223
-
Production of infectious hepatitis C virus in primary cultures of human adult hepatocytes
-
P. Podevin, A. Carpentier, V. Pene, L. Aoudjehane, M. Carriere, and S. Zaidi Production of infectious hepatitis C virus in primary cultures of human adult hepatocytes Gastroenterology 139 2010 1355 1364
-
(2010)
Gastroenterology
, vol.139
, pp. 1355-1364
-
-
Podevin, P.1
Carpentier, A.2
Pene, V.3
Aoudjehane, L.4
Carriere, M.5
Zaidi, S.6
-
29
-
-
77649262300
-
Persistent hepatitis C virus infection in microscale primary human hepatocyte cultures
-
A. Ploss, S.R. Khetani, C.T. Jones, A.J. Syder, K. Trehan, and V.A. Gaysinskaya Persistent hepatitis C virus infection in microscale primary human hepatocyte cultures Proc Natl Acad Sci U S A 107 2010 3141 3145
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 3141-3145
-
-
Ploss, A.1
Khetani, S.R.2
Jones, C.T.3
Syder, A.J.4
Trehan, K.5
Gaysinskaya, V.A.6
-
30
-
-
82455175215
-
Expression of paramyxovirus v proteins promotes replication and spread of hepatitis C virus in cultures of primary human fetal liver cells
-
L. Andrus, S. Marukian, C.T. Jones, M.T. Catanese, T.P. Sheahan, and J.W. Schoggins Expression of paramyxovirus V proteins promotes replication and spread of hepatitis C virus in cultures of primary human fetal liver cells Hepatology 54 2011 1901 1912
-
(2011)
Hepatology
, vol.54
, pp. 1901-1912
-
-
Andrus, L.1
Marukian, S.2
Jones, C.T.3
Catanese, M.T.4
Sheahan, T.P.5
Schoggins, J.W.6
-
31
-
-
82455188188
-
Hepatitis C virus induces interferon-lambda and interferon-stimulated genes in primary liver cultures
-
S. Marukian, L. Andrus, T.P. Sheahan, C.T. Jones, E.D. Charles, and A. Ploss Hepatitis C virus induces interferon-lambda and interferon-stimulated genes in primary liver cultures Hepatology 54 2011 1913 1923
-
(2011)
Hepatology
, vol.54
, pp. 1913-1923
-
-
Marukian, S.1
Andrus, L.2
Sheahan, T.P.3
Jones, C.T.4
Charles, E.D.5
Ploss, A.6
-
32
-
-
84865572917
-
Efficient replication of primary or culture hepatitis C virus isolates in human liver slices: A relevant ex vivo model of liver infection
-
S. Lagaye, H. Shen, B. Saunier, M. Nascimbeni, J. Gaston, and P. Bourdoncle Efficient replication of primary or culture hepatitis C virus isolates in human liver slices: a relevant ex vivo model of liver infection Hepatology 56 2012 861 872
-
(2012)
Hepatology
, vol.56
, pp. 861-872
-
-
Lagaye, S.1
Shen, H.2
Saunier, B.3
Nascimbeni, M.4
Gaston, J.5
Bourdoncle, P.6
-
33
-
-
84861206498
-
Productive hepatitis C virus infection of stem cell-derived hepatocytes reveals a critical transition to viral permissiveness during differentiation
-
X. Wu, J.M. Robotham, E. Lee, S. Dalton, N.M. Kneteman, and D.M. Gilbert Productive hepatitis C virus infection of stem cell-derived hepatocytes reveals a critical transition to viral permissiveness during differentiation PLoS Pathog 8 2012 e1002617
-
(2012)
PLoS Pathog
, vol.8
, pp. 1002617
-
-
Wu, X.1
Robotham, J.M.2
Lee, E.3
Dalton, S.4
Kneteman, N.M.5
Gilbert, D.M.6
-
34
-
-
84863982020
-
Human pluripotent stem cell-derived hepatocytes support complete replication of hepatitis C virus
-
P. Roelandt, S. Obeid, J. Paeshuyse, J. Vanhove, A. Van Lommel, and Y. Nahmias Human pluripotent stem cell-derived hepatocytes support complete replication of hepatitis C virus J Hepatol 57 2012 246 251
-
(2012)
J Hepatol
, vol.57
, pp. 246-251
-
-
Roelandt, P.1
Obeid, S.2
Paeshuyse, J.3
Vanhove, J.4
Van Lommel, A.5
Nahmias, Y.6
-
36
-
-
84922233514
-
Successful anti-SR-BI mAb therapy in humanized mice after challenge with HCV variants with in vitro resistance to SR-BI-targeting agents
-
[Epub ahead of print].
-
K. Vercauteren, N. Van Den Eede, A.A. Mesalam, S. Belouzard, M.T. Catanese, and D. Bankwitz Successful anti-SR-BI mAb therapy in humanized mice after challenge with HCV variants with in vitro resistance to SR-BI-targeting agents Hepatology 2014 [Epub ahead of print]. http://dx.doi.org/10.1002/hep.27196
-
(2014)
Hepatology
-
-
Vercauteren, K.1
Van Den Eede, N.2
Mesalam, A.A.3
Belouzard, S.4
Catanese, M.T.5
Bankwitz, D.6
-
37
-
-
17944379233
-
Hepatitis C virus replication in mice with chimeric human livers
-
D.F. Mercer, D.E. Schiller, J.F. Elliott, D.N. Douglas, C. Hao, and A. Rinfret Hepatitis C virus replication in mice with chimeric human livers Nat Med 7 2001 927 933
-
(2001)
Nat Med
, vol.7
, pp. 927-933
-
-
Mercer, D.F.1
Schiller, D.E.2
Elliott, J.F.3
Douglas, D.N.4
Hao, C.5
Rinfret, A.6
-
38
-
-
0037195180
-
Mutations that permit efficient replication of hepatitis C virus RNA in Huh-7 cells prevent productive replication in chimpanzees
-
J. Bukh, T. Pietschmann, V. Lohmann, N. Krieger, K. Faulk, and R.E. Engle Mutations that permit efficient replication of hepatitis C virus RNA in Huh-7 cells prevent productive replication in chimpanzees Proc Natl Acad Sci U S A 99 2002 14416 14421
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 14416-14421
-
-
Bukh, J.1
Pietschmann, T.2
Lohmann, V.3
Krieger, N.4
Faulk, K.5
Engle, R.E.6
-
39
-
-
84886772600
-
Hepatic cells derived from induced pluripotent stem cells of pigtail macaques support hepatitis C virus infection
-
M. Sourisseau, O. Goldman, W. He, J.L. Gori, H.P. Kiem, and V. Gouon-Evans Hepatic cells derived from induced pluripotent stem cells of pigtail macaques support hepatitis C virus infection Gastroenterology 145 2013 e967
-
(2013)
Gastroenterology
, vol.145
, pp. 967
-
-
Sourisseau, M.1
Goldman, O.2
He, W.3
Gori, J.L.4
Kiem, H.P.5
Gouon-Evans, V.6
-
40
-
-
0027662272
-
Lack of susceptibility of various primates and woodchucks to hepatitis C virus
-
K. Abe, T. Kurata, Y. Teramoto, J. Shiga, and T. Shikata Lack of susceptibility of various primates and woodchucks to hepatitis C virus J Med Primatol 22 1993 433 434
-
(1993)
J Med Primatol
, vol.22
, pp. 433-434
-
-
Abe, K.1
Kurata, T.2
Teramoto, Y.3
Shiga, J.4
Shikata, T.5
-
41
-
-
72849109817
-
Pathogenesis of hepatitis C virus infection in Tupaia belangeri
-
Y. Amako, K. Tsukiyama-Kohara, A. Katsume, Y. Hirata, S. Sekiguchi, and Y. Tobita Pathogenesis of hepatitis C virus infection in Tupaia belangeri J Virol 84 2010 303 311
-
(2010)
J Virol
, vol.84
, pp. 303-311
-
-
Amako, Y.1
Tsukiyama-Kohara, K.2
Katsume, A.3
Hirata, Y.4
Sekiguchi, S.5
Tobita, Y.6
-
42
-
-
84885335829
-
Hepatitis C virus infection and related liver disease: The quest for the best animal model
-
L. Mailly, E. Robinet, P. Meuleman, T.F. Baumert, and M.B. Zeisel Hepatitis C virus infection and related liver disease: the quest for the best animal model Front Microbiol 4 2013 213
-
(2013)
Front Microbiol
, vol.4
, pp. 213
-
-
Mailly, L.1
Robinet, E.2
Meuleman, P.3
Baumert, T.F.4
Zeisel, M.B.5
-
43
-
-
77957660356
-
Adaptation of hepatitis C virus to mouse CD81 permits infection of mouse cells in the absence of human entry factors
-
J. Bitzegeio, D. Bankwitz, K. Hueging, S. Haid, C. Brohm, and M.B. Zeisel Adaptation of hepatitis C virus to mouse CD81 permits infection of mouse cells in the absence of human entry factors PLoS Pathog 6 2010 e1000978
-
(2010)
PLoS Pathog
, vol.6
, pp. 1000978
-
-
Bitzegeio, J.1
Bankwitz, D.2
Hueging, K.3
Haid, S.4
Brohm, C.5
Zeisel, M.B.6
-
44
-
-
60149090028
-
Human occludin is a hepatitis C virus entry factor required for infection of mouse cells
-
A. Ploss, M.J. Evans, V.A. Gaysinskaya, M. Panis, H.N. You, and Y.P. de Jong Human occludin is a hepatitis C virus entry factor required for infection of mouse cells Nature 457 2009 882 886
-
(2009)
Nature
, vol.457
, pp. 882-886
-
-
Ploss, A.1
Evans, M.J.2
Gaysinskaya, V.A.3
Panis, M.4
You, H.N.5
De Jong, Y.P.6
-
45
-
-
84894132965
-
Cell entry, efficient RNA replication, and production of infectious hepatitis C virus progeny in mouse liver-derived cells
-
A. Frentzen, Anggakusuma, E. Gurlevik, K. Hueging, S. Knocke, and C. Ginkel Cell entry, efficient RNA replication, and production of infectious hepatitis C virus progeny in mouse liver-derived cells Hepatology 59 2014 78 88
-
(2014)
Hepatology
, vol.59
, pp. 78-88
-
-
Frentzen, A.1
Anggakusuma2
Gurlevik, E.3
Hueging, K.4
Knocke, S.5
Ginkel, C.6
-
46
-
-
33749177118
-
The hepatitis C virus and immune evasion: Non-structural 3/4A transgenic mice are resistant to lethal tumour necrosis factor alpha mediated liver disease
-
L. Frelin, E.D. Brenndorfer, G. Ahlen, M. Weiland, C. Hultgren, and M. Alheim The hepatitis C virus and immune evasion: non-structural 3/4A transgenic mice are resistant to lethal tumour necrosis factor alpha mediated liver disease Gut 55 2006 1475 1483
-
(2006)
Gut
, vol.55
, pp. 1475-1483
-
-
Frelin, L.1
Brenndorfer, E.D.2
Ahlen, G.3
Weiland, M.4
Hultgren, C.5
Alheim, M.6
-
47
-
-
0029585099
-
Expression of hepatitis C virus envelope proteins in transgenic mice
-
K. Koike, K. Moriya, K. Ishibashi, Y. Matsuura, T. Suzuki, and I. Saito Expression of hepatitis C virus envelope proteins in transgenic mice J Gen Virol 76 1995 3031 3038
-
(1995)
J Gen Virol
, vol.76
, pp. 3031-3038
-
-
Koike, K.1
Moriya, K.2
Ishibashi, K.3
Matsuura, Y.4
Suzuki, T.5
Saito, I.6
-
48
-
-
0030940874
-
Transgenic expression of hepatitis C virus structural proteins in the mouse
-
T. Kawamura, A. Furusaka, M.J. Koziel, R.T. Chung, T.C. Wang, and E.V. Schmidt Transgenic expression of hepatitis C virus structural proteins in the mouse Hepatology 25 1997 1014 1021
-
(1997)
Hepatology
, vol.25
, pp. 1014-1021
-
-
Kawamura, T.1
Furusaka, A.2
Koziel, M.J.3
Chung, R.T.4
Wang, T.C.5
Schmidt, E.V.6
-
49
-
-
0031057659
-
Hepatitis C virus core and E2 protein expression in transgenic mice
-
C. Pasquinelli, J.M. Shoenberger, J. Chung, K.M. Chang, L.G. Guidotti, and M. Selby Hepatitis C virus core and E2 protein expression in transgenic mice Hepatology 25 1997 719 727
-
(1997)
Hepatology
, vol.25
, pp. 719-727
-
-
Pasquinelli, C.1
Shoenberger, J.M.2
Chung, J.3
Chang, K.M.4
Guidotti, L.G.5
Selby, M.6
-
50
-
-
0030859121
-
Hepatitis C virus core protein induces hepatic steatosis in transgenic mice
-
K. Moriya, H. Yotsuyanagi, Y. Shintani, H. Fujie, K. Ishibashi, and Y. Matsuura Hepatitis C virus core protein induces hepatic steatosis in transgenic mice J Gen Virol 78 1997 1527 1531
-
(1997)
J Gen Virol
, vol.78
, pp. 1527-1531
-
-
Moriya, K.1
Yotsuyanagi, H.2
Shintani, Y.3
Fujie, H.4
Ishibashi, K.5
Matsuura, Y.6
-
51
-
-
0031712813
-
The core protein of hepatitis C virus induces hepatocellular carcinoma in transgenic mice
-
K. Moriya, H. Fujie, Y. Shintani, H. Yotsuyanagi, T. Tsutsumi, and K. Ishibashi The core protein of hepatitis C virus induces hepatocellular carcinoma in transgenic mice Nat Med 4 1998 1065 1067
-
(1998)
Nat Med
, vol.4
, pp. 1065-1067
-
-
Moriya, K.1
Fujie, H.2
Shintani, Y.3
Yotsuyanagi, H.4
Tsutsumi, T.5
Ishibashi, K.6
-
52
-
-
14244261930
-
Hepatitis C virus acts as a tumor accelerator by blocking apoptosis in a mouse model of hepatocarcinogenesis
-
Y. Kamegaya, Y. Hiasa, L. Zukerberg, N. Fowler, J.T. Blackard, and W. Lin Hepatitis C virus acts as a tumor accelerator by blocking apoptosis in a mouse model of hepatocarcinogenesis Hepatology 41 2005 660 667
-
(2005)
Hepatology
, vol.41
, pp. 660-667
-
-
Kamegaya, Y.1
Hiasa, Y.2
Zukerberg, L.3
Fowler, N.4
Blackard, J.T.5
Lin, W.6
-
53
-
-
0036063623
-
Hepatitis C virus NS5A protein impairs TNF-mediated hepatic apoptosis, but not by an anti-FAS antibody, in transgenic mice
-
M. Majumder, A.K. Ghosh, R. Steele, X.Y. Zhou, N.J. Phillips, and R. Ray Hepatitis C virus NS5A protein impairs TNF-mediated hepatic apoptosis, but not by an anti-FAS antibody, in transgenic mice Virology 294 2002 94 105
-
(2002)
Virology
, vol.294
, pp. 94-105
-
-
Majumder, M.1
Ghosh, A.K.2
Steele, R.3
Zhou, X.Y.4
Phillips, N.J.5
Ray, R.6
-
54
-
-
84871333031
-
Immunization with a recombinant vaccinia virus that encodes nonstructural proteins of the hepatitis C virus suppresses viral protein levels in mouse liver
-
S. Sekiguchi, K. Kimura, T. Chiyo, T. Ohtsuki, Y. Tobita, and Y. Tokunaga Immunization with a recombinant vaccinia virus that encodes nonstructural proteins of the hepatitis C virus suppresses viral protein levels in mouse liver PLoS One 7 2012 e51656
-
(2012)
PLoS One
, vol.7
, pp. 51656
-
-
Sekiguchi, S.1
Kimura, K.2
Chiyo, T.3
Ohtsuki, T.4
Tobita, Y.5
Tokunaga, Y.6
-
55
-
-
28844440938
-
In vivo clearance of hepatitis C virus nonstructural 3/4A-expressing hepatocytes by DNA vaccine-primed cytotoxic T lymphocytes
-
G. Ahlen, J. Nystrom, I. Pult, L. Frelin, C. Hultgren, and M. Sallberg In vivo clearance of hepatitis C virus nonstructural 3/4A-expressing hepatocytes by DNA vaccine-primed cytotoxic T lymphocytes J Infect Dis 192 2005 2112 2116
-
(2005)
J Infect Dis
, vol.192
, pp. 2112-2116
-
-
Ahlen, G.1
Nystrom, J.2
Pult, I.3
Frelin, L.4
Hultgren, C.5
Sallberg, M.6
-
56
-
-
79955527858
-
Heterologous T cells can help restore function in dysfunctional hepatitis C virus nonstructural 3/4A-specific T cells during therapeutic vaccination
-
A. Chen, G. Ahlen, E.D. Brenndorfer, A. Brass, F. Holmstrom, and M. Chen Heterologous T cells can help restore function in dysfunctional hepatitis C virus nonstructural 3/4A-specific T cells during therapeutic vaccination J Immunol 186 2011 5107 5118
-
(2011)
J Immunol
, vol.186
, pp. 5107-5118
-
-
Chen, A.1
Ahlen, G.2
Brenndorfer, E.D.3
Brass, A.4
Holmstrom, F.5
Chen, M.6
-
57
-
-
0036158719
-
Steatosis and liver cancer in transgenic mice expressing the structural and nonstructural proteins of hepatitis C virus
-
H. Lerat, M. Honda, M.R. Beard, K. Loesch, J. Sun, and Y. Yang Steatosis and liver cancer in transgenic mice expressing the structural and nonstructural proteins of hepatitis C virus Gastroenterology 122 2002 352 365
-
(2002)
Gastroenterology
, vol.122
, pp. 352-365
-
-
Lerat, H.1
Honda, M.2
Beard, M.R.3
Loesch, K.4
Sun, J.5
Yang, Y.6
-
58
-
-
70450245165
-
Hepatitis C virus proteins induce lipogenesis and defective triglyceride secretion in transgenic mice
-
H. Lerat, H.L. Kammoun, I. Hainault, E. Merour, M.R. Higgs, and C. Callens Hepatitis C virus proteins induce lipogenesis and defective triglyceride secretion in transgenic mice J Biol Chem 284 2009 33466 33474
-
(2009)
J Biol Chem
, vol.284
, pp. 33466-33474
-
-
Lerat, H.1
Kammoun, H.L.2
Hainault, I.3
Merour, E.4
Higgs, M.R.5
Callens, C.6
-
59
-
-
84865146104
-
Hepatitis C virus (HCV) protein expression enhances hepatic fibrosis in HCV transgenic mice exposed to a fibrogenic agent
-
P. Chouteau, N. Defer, A. Florimond, J. Calderaro, M. Higgs, and A. Gaudin Hepatitis C virus (HCV) protein expression enhances hepatic fibrosis in HCV transgenic mice exposed to a fibrogenic agent J Hepatol 57 2012 499 507
-
(2012)
J Hepatol
, vol.57
, pp. 499-507
-
-
Chouteau, P.1
Defer, N.2
Florimond, A.3
Calderaro, J.4
Higgs, M.5
Gaudin, A.6
-
60
-
-
79958291149
-
A genetically humanized mouse model for hepatitis C virus infection
-
M. Dorner, J.A. Horwitz, J.B. Robbins, W.T. Barry, Q. Feng, and K. Mu A genetically humanized mouse model for hepatitis C virus infection Nature 474 2011 208 211
-
(2011)
Nature
, vol.474
, pp. 208-211
-
-
Dorner, M.1
Horwitz, J.A.2
Robbins, J.B.3
Barry, W.T.4
Feng, Q.5
Mu, K.6
-
61
-
-
84859965965
-
Human broadly neutralizing antibodies to the envelope glycoprotein complex of hepatitis C virus
-
E. Giang, M. Dorner, J.C. Prentoe, M. Dreux, M.J. Evans, and J. Bukh Human broadly neutralizing antibodies to the envelope glycoprotein complex of hepatitis C virus Proc Natl Acad Sci U S A 109 2012 6205 6210
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 6205-6210
-
-
Giang, E.1
Dorner, M.2
Prentoe, J.C.3
Dreux, M.4
Evans, M.J.5
Bukh, J.6
-
62
-
-
84902272542
-
Turmeric curcumin inhibits entry of all hepatitis C virus genotypes into human liver cells
-
Anggakusuma, C.C. Colpitts, L.M. Schang, H. Rachmawati, A. Frentzen, and S. Pfaender Turmeric curcumin inhibits entry of all hepatitis C virus genotypes into human liver cells Gut 63 7 2013 1137 1149
-
(2013)
Gut
, vol.63
, Issue.7
, pp. 1137-1149
-
-
Anggakusuma1
Colpitts, C.C.2
Schang, L.M.3
Rachmawati, H.4
Frentzen, A.5
Pfaender, S.6
-
63
-
-
79955752803
-
Completion of hepatitis C virus replication cycle in heterokaryons excludes dominant restrictions in human non-liver and mouse liver cell lines
-
A. Frentzen, K. Huging, J. Bitzegeio, M. Friesland, S. Haid, and J. Gentzsch Completion of hepatitis C virus replication cycle in heterokaryons excludes dominant restrictions in human non-liver and mouse liver cell lines PLoS Pathog 7 2011 e1002029
-
(2011)
PLoS Pathog
, vol.7
, pp. 1002029
-
-
Frentzen, A.1
Huging, K.2
Bitzegeio, J.3
Friesland, M.4
Haid, S.5
Gentzsch, J.6
-
64
-
-
0041888351
-
Replication of hepatitis C virus subgenomes in nonhepatic epithelial and mouse hepatoma cells
-
Q. Zhu, J.T. Guo, and C. Seeger Replication of hepatitis C virus subgenomes in nonhepatic epithelial and mouse hepatoma cells J Virol 77 2003 9204 9210
-
(2003)
J Virol
, vol.77
, pp. 9204-9210
-
-
Zhu, Q.1
Guo, J.T.2
Seeger, C.3
-
65
-
-
33750804220
-
Replication of a hepatitis C virus replicon clone in mouse cells
-
S.L. Uprichard, J. Chung, F.V. Chisari, and T. Wakita Replication of a hepatitis C virus replicon clone in mouse cells Virol J 3 2006 89
-
(2006)
Virol J
, vol.3
, pp. 89
-
-
Uprichard, S.L.1
Chung, J.2
Chisari, F.V.3
Wakita, T.4
-
66
-
-
80052131312
-
Mouse hepatic cells support assembly of infectious hepatitis C virus particles
-
G. Long, M.S. Hiet, M.P. Windisch, J.Y. Lee, V. Lohmann, and R. Bartenschlager Mouse hepatic cells support assembly of infectious hepatitis C virus particles Gastroenterology 141 2011 1057 1066
-
(2011)
Gastroenterology
, vol.141
, pp. 1057-1066
-
-
Long, G.1
Hiet, M.S.2
Windisch, M.P.3
Lee, J.Y.4
Lohmann, V.5
Bartenschlager, R.6
-
67
-
-
84884150486
-
Completion of the entire hepatitis C virus life cycle in genetically humanized mice
-
M. Dorner, J.A. Horwitz, B.M. Donovan, R.N. Labitt, W.C. Budell, and T. Friling Completion of the entire hepatitis C virus life cycle in genetically humanized mice Nature 501 2013 237 241
-
(2013)
Nature
, vol.501
, pp. 237-241
-
-
Dorner, M.1
Horwitz, J.A.2
Donovan, B.M.3
Labitt, R.N.4
Budell, W.C.5
Friling, T.6
-
68
-
-
17744378552
-
Repopulation of mouse liver with human hepatocytes and in vivo infection with hepatitis B virus
-
M. Dandri, M.R. Burda, E. Torok, J.M. Pollok, A. Iwanska, and G. Sommer Repopulation of mouse liver with human hepatocytes and in vivo infection with hepatitis B virus Hepatology 33 2001 981 988
-
(2001)
Hepatology
, vol.33
, pp. 981-988
-
-
Dandri, M.1
Burda, M.R.2
Torok, E.3
Pollok, J.M.4
Iwanska, A.5
Sommer, G.6
-
69
-
-
16244415868
-
Morphological and biochemical characterization of a human liver in a uPA-SCID mouse chimera
-
P. Meuleman, L. Libbrecht, R. De Vos, B. de Hemptinne, K. Gevaert, and J. Vandekerckhove Morphological and biochemical characterization of a human liver in a uPA-SCID mouse chimera Hepatology 41 2005 847 856
-
(2005)
Hepatology
, vol.41
, pp. 847-856
-
-
Meuleman, P.1
Libbrecht, L.2
De Vos, R.3
De Hemptinne, B.4
Gevaert, K.5
Vandekerckhove, J.6
-
70
-
-
34547730702
-
Robust expansion of human hepatocytes in Fah-/-/Rag2-/-/Il2rg-/- mice
-
H. Azuma, N. Paulk, A. Ranade, C. Dorrell, M. Al-Dhalimy, and E. Ellis Robust expansion of human hepatocytes in Fah-/-/Rag2-/-/Il2rg-/- mice Nat Biotechnol 25 2007 903 910
-
(2007)
Nat Biotechnol
, vol.25
, pp. 903-910
-
-
Azuma, H.1
Paulk, N.2
Ranade, A.3
Dorrell, C.4
Al-Dhalimy, M.5
Ellis, E.6
-
71
-
-
38049164210
-
Repopulation of adult and neonatal mice with human hepatocytes: A chimeric animal model
-
K.D. Bissig, T.T. Le, N.B. Woods, and I.M. Verma Repopulation of adult and neonatal mice with human hepatocytes: a chimeric animal model Proc Natl Acad Sci U S A 104 2007 20507 20511
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 20507-20511
-
-
Bissig, K.D.1
Le, T.T.2
Woods, N.B.3
Verma, I.M.4
-
72
-
-
77949725830
-
Human liver chimeric mice provide a model for hepatitis B and C virus infection and treatment
-
K.D. Bissig, S.F. Wieland, P. Tran, M. Isogawa, T.T. Le, and F.V. Chisari Human liver chimeric mice provide a model for hepatitis B and C virus infection and treatment J Clin Invest 120 2010 924 930
-
(2010)
J Clin Invest
, vol.120
, pp. 924-930
-
-
Bissig, K.D.1
Wieland, S.F.2
Tran, P.3
Isogawa, M.4
Le, T.T.5
Chisari, F.V.6
-
73
-
-
0025781894
-
Complete hepatic regeneration after somatic deletion of an albumin-plasminogen activator transgene
-
E.P. Sandgren, R.D. Palmiter, J.L. Heckel, C.C. Daugherty, R.L. Brinster, and J.L. Degen Complete hepatic regeneration after somatic deletion of an albumin-plasminogen activator transgene Cell 66 1991 245 256
-
(1991)
Cell
, vol.66
, pp. 245-256
-
-
Sandgren, E.P.1
Palmiter, R.D.2
Heckel, J.L.3
Daugherty, C.C.4
Brinster, R.L.5
Degen, J.L.6
-
74
-
-
0029875835
-
Hepatocytes corrected by gene therapy are selected in vivo in a murine model of hereditary tyrosinemia type i
-
K. Overturf, M. Al-Dhalimy, R. Tanguay, M. Brantly, C.N. Ou, and M. Finegold Hepatocytes corrected by gene therapy are selected in vivo in a murine model of hereditary tyrosinemia type I Nat Genet 12 1996 266 273
-
(1996)
Nat Genet
, vol.12
, pp. 266-273
-
-
Overturf, K.1
Al-Dhalimy, M.2
Tanguay, R.3
Brantly, M.4
Ou, C.N.5
Finegold, M.6
-
75
-
-
0031279135
-
Hepatocytes break the rules of senescence in serial transplantation studies. is there a limit to their replicative capacity?
-
N. Fausto Hepatocytes break the rules of senescence in serial transplantation studies. Is there a limit to their replicative capacity? Am J Pathol 151 1997 1187 1189
-
(1997)
Am J Pathol
, vol.151
, pp. 1187-1189
-
-
Fausto, N.1
-
76
-
-
0034007745
-
Liver regeneration
-
N. Fausto Liver regeneration J Hepatol 32 2000 19 31
-
(2000)
J Hepatol
, vol.32
, pp. 19-31
-
-
Fausto, N.1
-
79
-
-
0034802517
-
Woodchuck hepatocytes remain permissive for hepadnavirus infection and mouse liver repopulation after cryopreservation
-
M. Dandri, M.R. Burda, A. Gocht, E. Torok, J.M. Pollok, and C.E. Rogler Woodchuck hepatocytes remain permissive for hepadnavirus infection and mouse liver repopulation after cryopreservation Hepatology 34 2001 824 833
-
(2001)
Hepatology
, vol.34
, pp. 824-833
-
-
Dandri, M.1
Burda, M.R.2
Gocht, A.3
Torok, E.4
Pollok, J.M.5
Rogler, C.E.6
-
80
-
-
0041592517
-
A simple and rapid method to determine the zygosity of uPA-transgenic SCID mice
-
P. Meuleman, P. Vanlandschoot, and G. Leroux-Roels A simple and rapid method to determine the zygosity of uPA-transgenic SCID mice Biochem Biophys Res Commun 308 2003 375 378
-
(2003)
Biochem Biophys Res Commun
, vol.308
, pp. 375-378
-
-
Meuleman, P.1
Vanlandschoot, P.2
Leroux-Roels, G.3
-
81
-
-
77955853940
-
Factors determining successful engraftment of hepatocytes and susceptibility to hepatitis B and C virus infection in uPA-SCID mice
-
T. Vanwolleghem, L. Libbrecht, B.E. Hansen, I. Desombere, T. Roskams, and P. Meuleman Factors determining successful engraftment of hepatocytes and susceptibility to hepatitis B and C virus infection in uPA-SCID mice J Hepatol 53 2010 468 476
-
(2010)
J Hepatol
, vol.53
, pp. 468-476
-
-
Vanwolleghem, T.1
Libbrecht, L.2
Hansen, B.E.3
Desombere, I.4
Roskams, T.5
Meuleman, P.6
-
82
-
-
77955852811
-
Host and viral determinants for engraftment of virus permissive human hepatocytes into chimeric immunodeficient mice
-
E. Robinet, and T.F. Baumert Host and viral determinants for engraftment of virus permissive human hepatocytes into chimeric immunodeficient mice J Hepatol 53 2010 421 423
-
(2010)
J Hepatol
, vol.53
, pp. 421-423
-
-
Robinet, E.1
Baumert, T.F.2
-
83
-
-
33644862356
-
Cell culture-grown hepatitis C virus is infectious in vivo and can be recultured in vitro
-
B.D. Lindenbach, P. Meuleman, A. Ploss, T. Vanwolleghem, A.J. Syder, and J.A. McKeating Cell culture-grown hepatitis C virus is infectious in vivo and can be recultured in vitro Proc Natl Acad Sci U S A 103 2006 3805 3809
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 3805-3809
-
-
Lindenbach, B.D.1
Meuleman, P.2
Ploss, A.3
Vanwolleghem, T.4
Syder, A.J.5
McKeating, J.A.6
-
84
-
-
77950960661
-
Challenge pools of hepatitis C virus genotypes 1-6 prototype strains: Replication fitness and pathogenicity in chimpanzees and human liver-chimeric mouse models
-
J. Bukh, P. Meuleman, R. Tellier, R.E. Engle, S.M. Feinstone, and G. Eder Challenge pools of hepatitis C virus genotypes 1-6 prototype strains: replication fitness and pathogenicity in chimpanzees and human liver-chimeric mouse models J Infect Dis 201 2010 1381 1389
-
(2010)
J Infect Dis
, vol.201
, pp. 1381-1389
-
-
Bukh, J.1
Meuleman, P.2
Tellier, R.3
Engle, R.E.4
Feinstone, S.M.5
Eder, G.6
-
85
-
-
79952205644
-
In vivo evaluation of the cross-genotype neutralizing activity of polyclonal antibodies against hepatitis C virus
-
P. Meuleman, J. Bukh, L. Verhoye, A. Farhoudi, T. Vanwolleghem, and R.Y. Wang In vivo evaluation of the cross-genotype neutralizing activity of polyclonal antibodies against hepatitis C virus Hepatology 53 2011 755 762
-
(2011)
Hepatology
, vol.53
, pp. 755-762
-
-
Meuleman, P.1
Bukh, J.2
Verhoye, L.3
Farhoudi, A.4
Vanwolleghem, T.5
Wang, R.Y.6
-
86
-
-
36348950345
-
Cell culture adaptation of hepatitis C virus and in vivo viability of an adapted variant
-
A. Kaul, I. Woerz, P. Meuleman, G. Leroux-Roels, and R. Bartenschlager Cell culture adaptation of hepatitis C virus and in vivo viability of an adapted variant J Virol 81 2007 13168 13179
-
(2007)
J Virol
, vol.81
, pp. 13168-13179
-
-
Kaul, A.1
Woerz, I.2
Meuleman, P.3
Leroux-Roels, G.4
Bartenschlager, R.5
-
87
-
-
56449110274
-
Role of the hepatitis C virus core+1 open reading frame and core cis-acting RNA elements in viral RNA translation and replication
-
N. Vassilaki, P. Friebe, P. Meuleman, S. Kallis, A. Kaul, and G. Paranhos-Baccala Role of the hepatitis C virus core+1 open reading frame and core cis-acting RNA elements in viral RNA translation and replication J Virol 82 2008 11503 11515
-
(2008)
J Virol
, vol.82
, pp. 11503-11515
-
-
Vassilaki, N.1
Friebe, P.2
Meuleman, P.3
Kallis, S.4
Kaul, A.5
Paranhos-Baccala, G.6
-
88
-
-
61449181271
-
HCV induces oxidative and ER stress, and sensitizes infected cells to apoptosis in SCID/Alb-uPA mice
-
M.A. Joyce, K.A. Walters, S.E. Lamb, M.M. Yeh, L.F. Zhu, and N. Kneteman HCV induces oxidative and ER stress, and sensitizes infected cells to apoptosis in SCID/Alb-uPA mice PLoS Pathog 5 2009 e1000291
-
(2009)
PLoS Pathog
, vol.5
, pp. 1000291
-
-
Joyce, M.A.1
Walters, K.A.2
Lamb, S.E.3
Yeh, M.M.4
Zhu, L.F.5
Kneteman, N.6
-
89
-
-
59249089462
-
Genomic analysis reveals a potential role for cell cycle perturbation in HCV-mediated apoptosis of cultured hepatocytes
-
K.A. Walters, A.J. Syder, S.L. Lederer, D.L. Diamond, B. Paeper, and C.M. Rice Genomic analysis reveals a potential role for cell cycle perturbation in HCV-mediated apoptosis of cultured hepatocytes PLoS Pathog 5 2009 e1000269
-
(2009)
PLoS Pathog
, vol.5
, pp. 1000269
-
-
Walters, K.A.1
Syder, A.J.2
Lederer, S.L.3
Diamond, D.L.4
Paeper, B.5
Rice, C.M.6
-
90
-
-
67650882702
-
Production of infectious genotype 1b virus particles in cell culture and impairment by replication enhancing mutations
-
T. Pietschmann, M. Zayas, P. Meuleman, G. Long, N. Appel, and G. Koutsoudakis Production of infectious genotype 1b virus particles in cell culture and impairment by replication enhancing mutations PLoS Pathog 5 2009 e1000475
-
(2009)
PLoS Pathog
, vol.5
, pp. 1000475
-
-
Pietschmann, T.1
Zayas, M.2
Meuleman, P.3
Long, G.4
Appel, N.5
Koutsoudakis, G.6
-
91
-
-
77956147218
-
Viral entry and escape from antibody-mediated neutralization influence hepatitis C virus reinfection in liver transplantation
-
S. Fafi-Kremer, I. Fofana, E. Soulier, P. Carolla, P. Meuleman, and G. Leroux-Roels Viral entry and escape from antibody-mediated neutralization influence hepatitis C virus reinfection in liver transplantation J Exp Med 207 2010 2019 2031
-
(2010)
J Exp Med
, vol.207
, pp. 2019-2031
-
-
Fafi-Kremer, S.1
Fofana, I.2
Soulier, E.3
Carolla, P.4
Meuleman, P.5
Leroux-Roels, G.6
-
92
-
-
80052283930
-
Development and application of hepatitis C reporter viruses with genotype 1 to 7 core-nonstructural protein 2 (NS2) expressing fluorescent proteins or luciferase in modified JFH1 NS5A
-
J.M. Gottwein, T.B. Jensen, C.K. Mathiesen, P. Meuleman, S.B. Serre, and J.B. Lademann Development and application of hepatitis C reporter viruses with genotype 1 to 7 core-nonstructural protein 2 (NS2) expressing fluorescent proteins or luciferase in modified JFH1 NS5A J Virol 85 2011 8913 8928
-
(2011)
J Virol
, vol.85
, pp. 8913-8928
-
-
Gottwein, J.M.1
Jensen, T.B.2
Mathiesen, C.K.3
Meuleman, P.4
Serre, S.B.5
Lademann, J.B.6
-
93
-
-
84869143643
-
Hepatitis C virus envelope glycoprotein fitness defines virus population composition following transmission to a new host
-
R.J. Brown, N. Hudson, G. Wilson, S.U. Rehman, S. Jabbari, and K. Hu Hepatitis C virus envelope glycoprotein fitness defines virus population composition following transmission to a new host J Virol 86 2012 11956 11966
-
(2012)
J Virol
, vol.86
, pp. 11956-11966
-
-
Brown, R.J.1
Hudson, N.2
Wilson, G.3
Rehman, S.U.4
Jabbari, S.5
Hu, K.6
-
94
-
-
84878610529
-
Thermostability of seven hepatitis C virus genotypes in vitro and in vivo
-
J. Doerrbecker, P. Meuleman, J. Kang, N. Riebesehl, C. Wilhelm, and M. Friesland Thermostability of seven hepatitis C virus genotypes in vitro and in vivo J Viral Hepat 20 2013 478 485
-
(2013)
J Viral Hepat
, vol.20
, pp. 478-485
-
-
Doerrbecker, J.1
Meuleman, P.2
Kang, J.3
Riebesehl, N.4
Wilhelm, C.5
Friesland, M.6
-
95
-
-
84894864720
-
Hepatitis C virus induced up-regulation of microRNA-27: A novel mechanism for hepatic steatosis
-
R. Singaravelu, R. Chen, R.K. Lyn, D.M. Jones, S. O'Hara, and Y. Rouleau Hepatitis C virus induced up-regulation of microRNA-27: a novel mechanism for hepatic steatosis Hepatology 59 2014 98 108
-
(2014)
Hepatology
, vol.59
, pp. 98-108
-
-
Singaravelu, R.1
Chen, R.2
Lyn, R.K.3
Jones, D.M.4
O'Hara, S.5
Rouleau, Y.6
-
96
-
-
46249125111
-
Polyclonal immunoglobulins from a chronic hepatitis C virus patient protect human liver-chimeric mice from infection with a homologous hepatitis C virus strain
-
T. Vanwolleghem, J. Bukh, P. Meuleman, I. Desombere, J.C. Meunier, and H. Alter Polyclonal immunoglobulins from a chronic hepatitis C virus patient protect human liver-chimeric mice from infection with a homologous hepatitis C virus strain Hepatology 47 2008 1846 1855
-
(2008)
Hepatology
, vol.47
, pp. 1846-1855
-
-
Vanwolleghem, T.1
Bukh, J.2
Meuleman, P.3
Desombere, I.4
Meunier, J.C.5
Alter, H.6
-
97
-
-
38049083122
-
Broadly neutralizing antibodies protect against hepatitis C virus quasispecies challenge
-
M. Law, T. Maruyama, J. Lewis, E. Giang, A.W. Tarr, and Z. Stamataki Broadly neutralizing antibodies protect against hepatitis C virus quasispecies challenge Nat Med 14 2008 25 27
-
(2008)
Nat Med
, vol.14
, pp. 25-27
-
-
Law, M.1
Maruyama, T.2
Lewis, J.3
Giang, E.4
Tarr, A.W.5
Stamataki, Z.6
-
98
-
-
84880575939
-
Neutralizing antibodies induced by cell culture-derived hepatitis C virus protect against infection in mice
-
D. Akazawa, M. Moriyama, H. Yokokawa, N. Omi, N. Watanabe, and T. Date Neutralizing antibodies induced by cell culture-derived hepatitis C virus protect against infection in mice Gastroenterology 145 2013 e441 e444
-
(2013)
Gastroenterology
, vol.145
, pp. 441-e444
-
-
Akazawa, D.1
Moriyama, M.2
Yokokawa, H.3
Omi, N.4
Watanabe, N.5
Date, T.6
-
99
-
-
34848881891
-
Ultra-rapid cardiotoxicity of the hepatitis C virus protease inhibitor BILN 2061 in the urokinase-type plasminogen activator mouse
-
T. Vanwolleghem, P. Meuleman, L. Libbrecht, T. Roskams, R. De Vos, and G. Leroux-Roels Ultra-rapid cardiotoxicity of the hepatitis C virus protease inhibitor BILN 2061 in the urokinase-type plasminogen activator mouse Gastroenterology 133 2007 1144 1155
-
(2007)
Gastroenterology
, vol.133
, pp. 1144-1155
-
-
Vanwolleghem, T.1
Meuleman, P.2
Libbrecht, L.3
Roskams, T.4
De Vos, R.5
Leroux-Roels, G.6
-
100
-
-
58149384511
-
Anti-CD81 antibodies can prevent a hepatitis C virus infection in vivo
-
P. Meuleman, J. Hesselgesser, M. Paulson, T. Vanwolleghem, I. Desombere, and H. Reiser Anti-CD81 antibodies can prevent a hepatitis C virus infection in vivo Hepatology 48 2008 1761 1768
-
(2008)
Hepatology
, vol.48
, pp. 1761-1768
-
-
Meuleman, P.1
Hesselgesser, J.2
Paulson, M.3
Vanwolleghem, T.4
Desombere, I.5
Reiser, H.6
-
101
-
-
63349109767
-
HCV796: A selective nonstructural protein 5B polymerase inhibitor with potent anti-hepatitis C virus activity in vitro, in mice with chimeric human livers, and in humans infected with hepatitis C virus
-
N.M. Kneteman, A.Y. Howe, T. Gao, J. Lewis, D. Pevear, and G. Lund HCV796: a selective nonstructural protein 5B polymerase inhibitor with potent anti-hepatitis C virus activity in vitro, in mice with chimeric human livers, and in humans infected with hepatitis C virus Hepatology 49 2009 745 752
-
(2009)
Hepatology
, vol.49
, pp. 745-752
-
-
Kneteman, N.M.1
Howe, A.Y.2
Gao, T.3
Lewis, J.4
Pevear, D.5
Lund, G.6
-
102
-
-
80054679007
-
Griffithsin has antiviral activity against hepatitis C virus
-
P. Meuleman, A. Albecka, S. Belouzard, K. Vercauteren, L. Verhoye, and C. Wychowski Griffithsin has antiviral activity against hepatitis C virus Antimicrob Agents Chemother 55 2011 5159 5167
-
(2011)
Antimicrob Agents Chemother
, vol.55
, pp. 5159-5167
-
-
Meuleman, P.1
Albecka, A.2
Belouzard, S.3
Vercauteren, K.4
Verhoye, L.5
Wychowski, C.6
-
103
-
-
78651071881
-
Discovery of (7R)-14-cyclohexyl-7-{[2-(dimethylamino)ethyl](methyl) amino}-7,8-dihydro-6H-indolo[1,2-e][1,5]benzoxazocine-11-carboxylic acid (MK-3281), a potent and orally bioavailable finger-loop inhibitor of the hepatitis C virus NS5B polymerase
-
F. Narjes, B. Crescenzi, M. Ferrara, J. Habermann, S. Colarusso, and R. Ferreira Mdel Discovery of (7R)-14-cyclohexyl-7-{[2-(dimethylamino)ethyl](methyl) amino}-7,8-dihydro-6H-indolo[1,2-e][1,5]benzoxazocine-11-carboxylic acid (MK-3281), a potent and orally bioavailable finger-loop inhibitor of the hepatitis C virus NS5B polymerase J Med Chem 54 2011 289 301
-
(2011)
J Med Chem
, vol.54
, pp. 289-301
-
-
Narjes, F.1
Crescenzi, B.2
Ferrara, M.3
Habermann, J.4
Colarusso, S.5
Ferreira Mdel, R.6
-
104
-
-
79954911259
-
Elimination of hepatitis C virus by short term NS3-4A and NS5B inhibitor combination therapy in human hepatocyte chimeric mice
-
E. Ohara, N. Hiraga, M. Imamura, E. Iwao, N. Kamiya, and I. Yamada Elimination of hepatitis C virus by short term NS3-4A and NS5B inhibitor combination therapy in human hepatocyte chimeric mice J Hepatol 54 2011 872 878
-
(2011)
J Hepatol
, vol.54
, pp. 872-878
-
-
Ohara, E.1
Hiraga, N.2
Imamura, M.3
Iwao, E.4
Kamiya, N.5
Yamada, I.6
-
105
-
-
80054713474
-
A human monoclonal antibody targeting scavenger receptor class B type i precludes hepatitis C virus infection and viral spread in vitro and in vivo
-
P. Meuleman, M.T. Catanese, L. Verhoye, I. Desombere, A. Farhoudi, and C.T. Jones A human monoclonal antibody targeting scavenger receptor class B type I precludes hepatitis C virus infection and viral spread in vitro and in vivo Hepatology 55 2012 364 372
-
(2012)
Hepatology
, vol.55
, pp. 364-372
-
-
Meuleman, P.1
Catanese, M.T.2
Verhoye, L.3
Desombere, I.4
Farhoudi, A.5
Jones, C.T.6
-
106
-
-
84862652238
-
Novel human SR-BI antibodies prevent infection and dissemination of HCV in vitro and in humanized mice
-
K. Lacek, K. Vercauteren, K. Grzyb, M. Naddeo, L. Verhoye, and M.P. Slowikowski Novel human SR-BI antibodies prevent infection and dissemination of HCV in vitro and in humanized mice J Hepatol 57 2012 17 23
-
(2012)
J Hepatol
, vol.57
, pp. 17-23
-
-
Lacek, K.1
Vercauteren, K.2
Grzyb, K.3
Naddeo, M.4
Verhoye, L.5
Slowikowski, M.P.6
-
107
-
-
12444253844
-
Modified apoptotic molecule (BID) reduces hepatitis C virus infection in mice with chimeric human livers
-
E.C. Hsu, B. Hsi, M. Hirota-Tsuchihara, J. Ruland, C. Iorio, and F. Sarangi Modified apoptotic molecule (BID) reduces hepatitis C virus infection in mice with chimeric human livers Nat Biotechnol 21 2003 519 525
-
(2003)
Nat Biotechnol
, vol.21
, pp. 519-525
-
-
Hsu, E.C.1
Hsi, B.2
Hirota-Tsuchihara, M.3
Ruland, J.4
Iorio, C.5
Sarangi, F.6
-
108
-
-
0029082193
-
Pharmacological correction of neonatal lethal hepatic dysfunction in a murine model of hereditary tyrosinemia type i
-
M. Grompe, S. Lindstedt, M. Al-Dhalimy, N.G. Kennaway, J. Papaconstantinou, and C.A. Torres-Ramos Pharmacological correction of neonatal lethal hepatic dysfunction in a murine model of hereditary tyrosinemia type I Nat Genet 10 1995 453 460
-
(1995)
Nat Genet
, vol.10
, pp. 453-460
-
-
Grompe, M.1
Lindstedt, S.2
Al-Dhalimy, M.3
Kennaway, N.G.4
Papaconstantinou, J.5
Torres-Ramos, C.A.6
-
109
-
-
84885404327
-
Chimeric mouse model for the infection of hepatitis B and C viruses
-
A. Tesfaye, J. Stift, D. Maric, Q. Cui, H.P. Dienes, and S.M. Feinstone Chimeric mouse model for the infection of hepatitis B and C viruses PLoS One 8 2013 e77298
-
(2013)
PLoS One
, vol.8
, pp. 77298
-
-
Tesfaye, A.1
Stift, J.2
Maric, D.3
Cui, Q.4
Dienes, H.P.5
Feinstone, S.M.6
-
110
-
-
84887413159
-
A novel TK-NOG based humanized mouse model for the study of HBV and HCV infections
-
K. Kosaka, N. Hiraga, M. Imamura, S. Yoshimi, E. Murakami, and T. Nakahara A novel TK-NOG based humanized mouse model for the study of HBV and HCV infections Biochem Biophys Res Commun 441 2013 230 235
-
(2013)
Biochem Biophys Res Commun
, vol.441
, pp. 230-235
-
-
Kosaka, K.1
Hiraga, N.2
Imamura, M.3
Yoshimi, S.4
Murakami, E.5
Nakahara, T.6
-
111
-
-
33644777664
-
Immune suppression uncovers endogenous cytopathic effects of the hepatitis B virus
-
P. Meuleman, L. Libbrecht, S. Wieland, R. De Vos, N. Habib, and A. Kramvis Immune suppression uncovers endogenous cytopathic effects of the hepatitis B virus J Virol 80 2006 2797 2807
-
(2006)
J Virol
, vol.80
, pp. 2797-2807
-
-
Meuleman, P.1
Libbrecht, L.2
Wieland, S.3
De Vos, R.4
Habib, N.5
Kramvis, A.6
-
112
-
-
40449096921
-
Prevention of hepatitis B virus infection in vivo by entry inhibitors derived from the large envelope protein
-
J. Petersen, M. Dandri, W. Mier, M. Lutgehetmann, T. Volz, and F. von Weizsacker Prevention of hepatitis B virus infection in vivo by entry inhibitors derived from the large envelope protein Nat Biotechnol 26 2008 335 341
-
(2008)
Nat Biotechnol
, vol.26
, pp. 335-341
-
-
Petersen, J.1
Dandri, M.2
Mier, W.3
Lutgehetmann, M.4
Volz, T.5
Von Weizsacker, F.6
-
113
-
-
56349163205
-
The human liver-uPA-SCID mouse: A model for the evaluation of antiviral compounds against HBV and HCV
-
P. Meuleman, and G. Leroux-Roels The human liver-uPA-SCID mouse: a model for the evaluation of antiviral compounds against HBV and HCV Antiviral Res 80 2008 231 238
-
(2008)
Antiviral Res
, vol.80
, pp. 231-238
-
-
Meuleman, P.1
Leroux-Roels, G.2
-
114
-
-
77954226664
-
In vivo proliferation of hepadnavirus-infected hepatocytes induces loss of covalently closed circular DNA in mice
-
M. Lutgehetmann, T. Volz, A. Kopke, T. Broja, E. Tigges, and A.W. Lohse In vivo proliferation of hepadnavirus-infected hepatocytes induces loss of covalently closed circular DNA in mice Hepatology 52 2010 16 24
-
(2010)
Hepatology
, vol.52
, pp. 16-24
-
-
Lutgehetmann, M.1
Volz, T.2
Kopke, A.3
Broja, T.4
Tigges, E.5
Lohse, A.W.6
-
115
-
-
84856514985
-
IFN-alpha inhibits HBV transcription and replication in cell culture and in humanized mice by targeting the epigenetic regulation of the nuclear cccDNA minichromosome
-
L. Belloni, L. Allweiss, F. Guerrieri, N. Pediconi, T. Volz, and T. Pollicino IFN-alpha inhibits HBV transcription and replication in cell culture and in humanized mice by targeting the epigenetic regulation of the nuclear cccDNA minichromosome J Clin Invest 122 2012 529 537
-
(2012)
J Clin Invest
, vol.122
, pp. 529-537
-
-
Belloni, L.1
Allweiss, L.2
Guerrieri, F.3
Pediconi, N.4
Volz, T.5
Pollicino, T.6
-
116
-
-
84857442747
-
Humanized chimeric uPA mouse model for the study of hepatitis B and D virus interactions and preclinical drug evaluation
-
M. Lutgehetmann, L.V. Mancke, T. Volz, M. Helbig, L. Allweiss, and T. Bornscheuer Humanized chimeric uPA mouse model for the study of hepatitis B and D virus interactions and preclinical drug evaluation Hepatology 55 2012 685 694
-
(2012)
Hepatology
, vol.55
, pp. 685-694
-
-
Lutgehetmann, M.1
Mancke, L.V.2
Volz, T.3
Helbig, M.4
Allweiss, L.5
Bornscheuer, T.6
-
117
-
-
84861716805
-
Strong antiviral activity of the new l-hydroxycytidine derivative, l-Hyd4FC, in HBV-infected human chimeric uPA/SCID mice
-
T. Volz, M. Lutgehetmann, L. Allweiss, M. Warlich, J. Bierwolf, and J.M. Pollok Strong antiviral activity of the new l-hydroxycytidine derivative, l-Hyd4FC, in HBV-infected human chimeric uPA/SCID mice Antivir Ther 17 2012 623 631
-
(2012)
Antivir Ther
, vol.17
, pp. 623-631
-
-
Volz, T.1
Lutgehetmann, M.2
Allweiss, L.3
Warlich, M.4
Bierwolf, J.5
Pollok, J.M.6
-
118
-
-
33644856082
-
Plasmodium falciparum infection and exoerythrocytic development in mice with chimeric human livers
-
J.B. Sacci Jr., U. Alam, D. Douglas, J. Lewis, D.L. Tyrrell, and A.F. Azad Plasmodium falciparum infection and exoerythrocytic development in mice with chimeric human livers Int J Parasitol 36 2006 353 360
-
(2006)
Int J Parasitol
, vol.36
, pp. 353-360
-
-
Sacci, J.B.1
Alam, U.2
Douglas, D.3
Lewis, J.4
Tyrrell, D.L.5
Azad, A.F.6
-
119
-
-
84867154422
-
Complete Plasmodium falciparum liver-stage development in liver-chimeric mice
-
A.M. Vaughan, S.A. Mikolajczak, E.M. Wilson, M. Grompe, A. Kaushansky, and N. Camargo Complete Plasmodium falciparum liver-stage development in liver-chimeric mice J Clin Invest 122 2012 3618 3628
-
(2012)
J Clin Invest
, vol.122
, pp. 3618-3628
-
-
Vaughan, A.M.1
Mikolajczak, S.A.2
Wilson, E.M.3
Grompe, M.4
Kaushansky, A.5
Camargo, N.6
-
120
-
-
69149109035
-
Preerythrocytic, live-attenuated Plasmodium falciparum vaccine candidates by design
-
K.M. VanBuskirk, M.T. O'Neill, P. De La Vega, A.G. Maier, U. Krzych, and J. Williams Preerythrocytic, live-attenuated Plasmodium falciparum vaccine candidates by design Proc Natl Acad Sci U S A 106 2009 13004 13009
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 13004-13009
-
-
Vanbuskirk, K.M.1
O'Neill, M.T.2
De La Vega, P.3
Maier, A.G.4
Krzych, U.5
Williams, J.6
-
121
-
-
84899474267
-
Sporozoite immunization of human volunteers under chemoprophylaxis induces functional antibodies against pre-erythrocytic stages of Plasmodium falciparum
-
M.C. Behet, L. Foquet, G.J. van Gemert, E.M. Bijker, P. Meuleman, and G. Leroux-Roels Sporozoite immunization of human volunteers under chemoprophylaxis induces functional antibodies against pre-erythrocytic stages of Plasmodium falciparum Malar J 13 2014 136
-
(2014)
Malar J
, vol.13
, pp. 136
-
-
Behet, M.C.1
Foquet, L.2
Van Gemert, G.J.3
Bijker, E.M.4
Meuleman, P.5
Leroux-Roels, G.6
-
122
-
-
84892931367
-
Vaccine-induced monoclonal antibodies targeting circumsporozoite protein prevent Plasmodium falciparum infection
-
L. Foquet, C.C. Hermsen, G.J. van Gemert, E. Van Braeckel, K.E. Weening, and R. Sauerwein Vaccine-induced monoclonal antibodies targeting circumsporozoite protein prevent Plasmodium falciparum infection J Clin Invest 124 2014 140 144
-
(2014)
J Clin Invest
, vol.124
, pp. 140-144
-
-
Foquet, L.1
Hermsen, C.C.2
Van Gemert, G.J.3
Van Braeckel, E.4
Weening, K.E.5
Sauerwein, R.6
-
123
-
-
84894103255
-
Persistent hepatitis D virus mono-infection in humanized mice is efficiently converted by hepatitis B virus to a productive co-infection
-
K. Giersch, M. Helbig, T. Volz, L. Allweiss, L.V. Mancke, and A.W. Lohse Persistent hepatitis D virus mono-infection in humanized mice is efficiently converted by hepatitis B virus to a productive co-infection J Hepatol 60 2014 538 544
-
(2014)
J Hepatol
, vol.60
, pp. 538-544
-
-
Giersch, K.1
Helbig, M.2
Volz, T.3
Allweiss, L.4
Mancke, L.V.5
Lohse, A.W.6
-
124
-
-
70349690193
-
UPA+/+-SCID mouse with humanized liver as a model for in vivo metabolism of exogenous steroids: Methandienone as a case study
-
L. Lootens, P. Meuleman, O.J. Pozo, P. Van Eenoo, G. Leroux-Roels, and F.T. Delbeke UPA+/+-SCID mouse with humanized liver as a model for in vivo metabolism of exogenous steroids: methandienone as a case study Clin Chem 55 2009 1783 1793
-
(2009)
Clin Chem
, vol.55
, pp. 1783-1793
-
-
Lootens, L.1
Meuleman, P.2
Pozo, O.J.3
Van Eenoo, P.4
Leroux-Roels, G.5
Delbeke, F.T.6
-
125
-
-
70350290234
-
Detection and characterization of a new metabolite of 17alpha-methyltestosterone
-
O.J. Pozo, P. Van Eenoo, K. Deventer, L. Lootens, W. Van Thuyne, and M.K. Parr Detection and characterization of a new metabolite of 17alpha-methyltestosterone Drug Metab Dispos 37 2009 2153 2162
-
(2009)
Drug Metab Dispos
, vol.37
, pp. 2153-2162
-
-
Pozo, O.J.1
Van Eenoo, P.2
Deventer, K.3
Lootens, L.4
Van Thuyne, W.5
Parr, M.K.6
-
126
-
-
78049374383
-
Chimeric mice with humanized liver: Tools for the study of drug metabolism, excretion, and toxicity
-
S.C. Strom, J. Davila, and M. Grompe Chimeric mice with humanized liver: tools for the study of drug metabolism, excretion, and toxicity Methods Mol Biol 640 2010 491 509
-
(2010)
Methods Mol Biol
, vol.640
, pp. 491-509
-
-
Strom, S.C.1
Davila, J.2
Grompe, M.3
-
127
-
-
84899484617
-
'Humanized' mouse detects deadly drug side effects
-
Cohen J. Toxicology 'Humanized' mouse detects deadly drug side effects Science 344 2014 244 245
-
(2014)
Science
, vol.344
, pp. 244-245
-
-
Toxicology, C.J.1
-
128
-
-
84901011638
-
Application of chimeric mice with humanized liver for study of human-specific drug metabolism
-
T.J. Bateman, V.G. Reddy, M. Kakuni, Y. Morikawa, and S. Kumar Application of chimeric mice with humanized liver for study of human-specific drug metabolism Drug Metab Dispos 42 2014 1055 1065
-
(2014)
Drug Metab Dispos
, vol.42
, pp. 1055-1065
-
-
Bateman, T.J.1
Reddy, V.G.2
Kakuni, M.3
Morikawa, Y.4
Kumar, S.5
-
129
-
-
84900460907
-
Fialuridine induces acute liver failure in chimeric TK-NOG mice: A model for detecting hepatic drug toxicity prior to human testing
-
D. Xu, T. Nishimura, S. Nishimura, H. Zhang, M. Zheng, and Y.Y. Guo Fialuridine induces acute liver failure in chimeric TK-NOG mice: a model for detecting hepatic drug toxicity prior to human testing PLoS Med 11 2014 e1001628
-
(2014)
PLoS Med
, vol.11
, pp. 1001628
-
-
Xu, D.1
Nishimura, T.2
Nishimura, S.3
Zhang, H.4
Zheng, M.5
Guo, Y.Y.6
-
130
-
-
0034954716
-
Transplantation of human hepatocytes into tolerized genetically immunocompetent rats
-
E.C. Ouyang, C.H. Wu, C. Walton, K. Promrat, and G.Y. Wu Transplantation of human hepatocytes into tolerized genetically immunocompetent rats World J Gastroenterol 7 2001 324 330
-
(2001)
World J Gastroenterol
, vol.7
, pp. 324-330
-
-
Ouyang, E.C.1
Wu, C.H.2
Walton, C.3
Promrat, K.4
Wu, G.Y.5
-
131
-
-
19044395632
-
A novel immunocompetent rat model of HCV infection and hepatitis
-
G.Y. Wu, M. Konishi, C.M. Walton, D. Olive, K. Hayashi, and C.H. Wu A novel immunocompetent rat model of HCV infection and hepatitis Gastroenterology 128 2005 1416 1423
-
(2005)
Gastroenterology
, vol.128
, pp. 1416-1423
-
-
Wu, G.Y.1
Konishi, M.2
Walton, C.M.3
Olive, D.4
Hayashi, K.5
Wu, C.H.6
-
132
-
-
84890386754
-
Human hepatocytes and hematolymphoid dual reconstitution in treosulfan-conditioned uPA-NOG mice
-
T.L. Gutti, J.S. Knibbe, E. Makarov, J. Zhang, G.R. Yannam, and S. Gorantla Human hepatocytes and hematolymphoid dual reconstitution in treosulfan-conditioned uPA-NOG mice Am J Pathol 184 2014 101 109
-
(2014)
Am J Pathol
, vol.184
, pp. 101-109
-
-
Gutti, T.L.1
Knibbe, J.S.2
Makarov, E.3
Zhang, J.4
Yannam, G.R.5
Gorantla, S.6
-
133
-
-
79953196869
-
A humanized mouse model to study hepatitis C virus infection, immune response, and liver disease
-
M.L. Washburn, M.T. Bility, L. Zhang, G.I. Kovalev, A. Buntzman, and J.A. Frelinger A humanized mouse model to study hepatitis C virus infection, immune response, and liver disease Gastroenterology 140 2011 1334 1344
-
(2011)
Gastroenterology
, vol.140
, pp. 1334-1344
-
-
Washburn, M.L.1
Bility, M.T.2
Zhang, L.3
Kovalev, G.I.4
Buntzman, A.5
Frelinger, J.A.6
-
134
-
-
77956265725
-
Induced pluripotent stem cells: A new era for hepatology
-
S. Asgari, B. Pournasr, G.H. Salekdeh, A. Ghodsizadeh, M. Ott, and H. Baharvand Induced pluripotent stem cells: a new era for hepatology J Hepatol 53 2010 738 751
-
(2010)
J Hepatol
, vol.53
, pp. 738-751
-
-
Asgari, S.1
Pournasr, B.2
Salekdeh, G.H.3
Ghodsizadeh, A.4
Ott, M.5
Baharvand, H.6
-
135
-
-
79955020052
-
In vitro generation of immune cells from pluripotent stem cells
-
B. Vandekerckhove, S. Vanhee, S. Van Coppernolle, S. Snauwaert, I. Velghe, and T. Taghon In vitro generation of immune cells from pluripotent stem cells Front Biosci 16 2011 1488 1504
-
(2011)
Front Biosci
, vol.16
, pp. 1488-1504
-
-
Vandekerckhove, B.1
Vanhee, S.2
Van Coppernolle, S.3
Snauwaert, S.4
Velghe, I.5
Taghon, T.6
-
136
-
-
0034885745
-
Studies of hepatitis C virus in chimpanzees and their importance for vaccine development
-
J. Bukh, X. Forns, S.U. Emerson, and R.H. Purcell Studies of hepatitis C virus in chimpanzees and their importance for vaccine development Intervirology 44 2001 132 142
-
(2001)
Intervirology
, vol.44
, pp. 132-142
-
-
Bukh, J.1
Forns, X.2
Emerson, S.U.3
Purcell, R.H.4
-
137
-
-
32244435842
-
A T-cell HCV vaccine eliciting effective immunity against heterologous virus challenge in chimpanzees
-
A. Folgori, S. Capone, L. Ruggeri, A. Meola, E. Sporeno, and B.B. Ercole A T-cell HCV vaccine eliciting effective immunity against heterologous virus challenge in chimpanzees Nat Med 12 2006 190 197
-
(2006)
Nat Med
, vol.12
, pp. 190-197
-
-
Folgori, A.1
Capone, S.2
Ruggeri, L.3
Meola, A.4
Sporeno, E.5
Ercole, B.B.6
-
138
-
-
74249112787
-
Therapeutic silencing of microRNA-122 in primates with chronic hepatitis C virus infection
-
R.E. Lanford, E.S. Hildebrandt-Eriksen, A. Petri, R. Persson, M. Lindow, and M.E. Munk Therapeutic silencing of microRNA-122 in primates with chronic hepatitis C virus infection Science 327 2010 198 201
-
(2010)
Science
, vol.327
, pp. 198-201
-
-
Lanford, R.E.1
Hildebrandt-Eriksen, E.S.2
Petri, A.3
Persson, R.4
Lindow, M.5
Munk, M.E.6
-
139
-
-
78751691624
-
Sustained viral response in a hepatitis C virus-infected chimpanzee via a combination of direct-acting antiviral agents
-
D.B. Olsen, M.E. Davies, L. Handt, K. Koeplinger, N.R. Zhang, and S.W. Ludmerer Sustained viral response in a hepatitis C virus-infected chimpanzee via a combination of direct-acting antiviral agents Antimicrob Agents Chemother 55 2011 937 939
-
(2011)
Antimicrob Agents Chemother
, vol.55
, pp. 937-939
-
-
Olsen, D.B.1
Davies, M.E.2
Handt, L.3
Koeplinger, K.4
Zhang, N.R.5
Ludmerer, S.W.6
|