-
1
-
-
44949107514
-
Critical role of virion-associated cholesterol and sphingolipid in hepatitis C virus infection
-
Aizaki H, et al. 2008. Critical role of virion-associated cholesterol and sphingolipid in hepatitis C virus infection. J. Virol. 82:5715-5724.
-
(2008)
J. Virol.
, vol.82
, pp. 5715-5724
-
-
Aizaki, H.1
-
2
-
-
34248370961
-
CD81 expression is important for the permissive-ness of Huh7 cell clones for heterogeneous hepatitis C virus infection
-
Akazawa D, et al. 2007. CD81 expression is important for the permissive-ness of Huh7 cell clones for heterogeneous hepatitis C virus infection. J. Virol. 81:5036-5045.
-
(2007)
J. Virol.
, vol.81
, pp. 5036-5045
-
-
Akazawa, D.1
-
3
-
-
79960620599
-
Production and characterization of HCV particles from serum-free culture
-
Akazawa D, et al. 2011. Production and characterization of HCV particles from serum-free culture. Vaccine 29:4821-4828.
-
(2011)
Vaccine
, vol.29
, pp. 4821-4828
-
-
Akazawa, D.1
-
5
-
-
0037195180
-
Mutations that permit efficient replication of hepatitis C virus RNA in Huh-7 cells prevent productive replication in chimpan-zees
-
U. S. A.
-
Bukh J, et al. 2002. Mutations that permit efficient replication of hepatitis C virus RNA in Huh-7 cells prevent productive replication in chimpan-zees. Proc. Natl. Acad. Sci. U. S. A. 99:14416-14421.
-
(2002)
Proc. Natl. Acad. Sci.
, vol.99
, pp. 14416-14421
-
-
Bukh, J.1
-
6
-
-
0024509701
-
Isolation of a cDNA clone derived from a blood- borne non-A non-B viral hepatitis genome
-
Choo QL, et al. 1989. Isolation of a cDNA clone derived from a blood- borne non-A non-B viral hepatitis genome. Science 244:359-362.
-
(1989)
Science
, vol.244
, pp. 359-362
-
-
Choo, Q.L.1
-
8
-
-
0029161576
-
Sensitivity to interferon is conferred by amino acid substitutions in the NS5A region
-
Enomoto N, et al. 1995. Sensitivity to interferon is conferred by amino acid substitutions in the NS5A region. J. Clin. Invest. 96:224-230.
-
(1995)
J. Clin. Invest.
, vol.96
, pp. 224-230
-
-
Enomoto, N.1
-
9
-
-
80052022434
-
Impact of viral amino acid substitutions and host interleukin-28b polymorphism on replication and susceptibility to inter-feron of hepatitis C virus
-
Hiraga N, et al. 2011. Impact of viral amino acid substitutions and host interleukin-28b polymorphism on replication and susceptibility to inter-feron of hepatitis C virus. Hepatology 54:764-771.
-
(2011)
Hepatology
, vol.54
, pp. 764-771
-
-
Hiraga, N.1
-
10
-
-
51349088324
-
Hepatitis C virus JFH-1 strain infection in chimpan- zees is associated with low pathogenicity and emergence of an adaptive mutation
-
Kato T, et al. 2008. Hepatitis C virus JFH-1 strain infection in chimpan- zees is associated with low pathogenicity and emergence of an adaptive mutation. Hepatology 48:732-740.
-
(2008)
Hepatology
, vol.48
, pp. 732-740
-
-
Kato, T.1
-
11
-
-
0345223476
-
Efficient replication of the genotype 2a hepatitis C virus subgenomic replicon
-
Kato T, et al. 2003. Efficient replication of the genotype 2a hepatitis C virus subgenomic replicon. Gastroenterology 125:1808-1817.
-
(2003)
Gastroenterology
, vol.125
, pp. 1808-1817
-
-
Kato, T.1
-
12
-
-
27744537836
-
Detection of anti-hepatitis C virus effects of interferon and ribavirin by a sensitive replicon system
-
Kato T, et al. 2005. Detection of anti-hepatitis C virus effects of interferon and ribavirin by a sensitive replicon system. J. Clin. Microbiol. 43:5679-5684.
-
(2005)
J. Clin. Microbiol.
, vol.43
, pp. 5679-5684
-
-
Kato, T.1
-
13
-
-
34548828780
-
Cell culture and infection system for hepatitis C virus
-
Kato T, et al. 2006. Cell culture and infection system for hepatitis C virus. Nat. Protoc. 1:2334-2339.
-
(2006)
Nat. Protoc.
, vol.1
, pp. 2334-2339
-
-
Kato, T.1
-
14
-
-
0034972539
-
Sequence analysis of hepatitis C virus isolated from a fulminant hepatitis patient
-
Kato T, et al. 2001. Sequence analysis of hepatitis C virus isolated from a fulminant hepatitis patient. J. Med. Virol. 64:334-339.
-
(2001)
J. Med. Virol.
, vol.64
, pp. 334-339
-
-
Kato, T.1
-
15
-
-
0037359844
-
Processing of hepatitis C virus core protein is regu- lated by its C-terminal sequence
-
Kato T, et al. 2003. Processing of hepatitis C virus core protein is regu- lated by its C-terminal sequence. J. Med. Virol. 69:357-366.
-
(2003)
J. Med. Virol.
, vol.69
, pp. 357-366
-
-
Kato, T.1
-
16
-
-
0025037547
-
Interrelationship of blood transfusion, non-A, non-B hepatitis and hepatocellular carcinoma: analysis by detection of antibody to hepatitis C virus
-
Kiyosawa K, et al. 1990. Interrelationship of blood transfusion, non-A, non-B hepatitis and hepatocellular carcinoma: analysis by detection of antibody to hepatitis C virus. Hepatology 12:671-675.
-
(1990)
Hepatology
, vol.12
, pp. 671-675
-
-
Kiyosawa, K.1
-
17
-
-
33747178354
-
Site-specific mutation of the interferon sensitivity-determining region (ISDR) modulates hepatitis C virus replication
-
Kohashi T, et al. 2006. Site-specific mutation of the interferon sensitivity-determining region (ISDR) modulates hepatitis C virus replication. J. Vi-ral Hepat. 13:582-590.
-
(2006)
J. Vi-ral Hepat.
, vol.13
, pp. 582-590
-
-
Kohashi, T.1
-
18
-
-
0030864915
-
Transmission of hepatitis C by intrahepatic inoculation with transcribed RNA
-
Kolykhalov AA, et al. 1997. Transmission of hepatitis C by intrahepatic inoculation with transcribed RNA. Science 277:570-574.
-
(1997)
Science
, vol.277
, pp. 570-574
-
-
Kolykhalov, A.A.1
-
19
-
-
0024511734
-
An assay for circulating antibodies to a major etiologic virus of human non-A non-B hepatitis
-
Kuo G, et al. 1989. An assay for circulating antibodies to a major etiologic virus of human non-A non-B hepatitis. Science 244:362-364.
-
(1989)
Science
, vol.244
, pp. 362-364
-
-
Kuo, G.1
-
20
-
-
23044437222
-
Complete replication of hepatitis C virus in cell culture
-
Lindenbach BD, et al. 2005. Complete replication of hepatitis C virus in cell culture. Science 309:623-626.
-
(2005)
Science
, vol.309
, pp. 623-626
-
-
Lindenbach, B.D.1
-
21
-
-
33644862356
-
Cell culture-grown hepatitis C virus is infec-tious in vivo and can be recultured in vitro
-
Lindenbach BD, et al. 2006. Cell culture-grown hepatitis C virus is infec-tious in vivo and can be recultured in vitro. Proc. Natl. Acad. Sci. U. S. A. 103:3805-3809.
-
(2006)
Proc. Natl. Acad. Sci. U. S. A.
, vol.103
, pp. 3805-3809
-
-
Lindenbach, B.D.1
-
22
-
-
0345188811
-
Replication of subgenomic hepatitis C virus RNAs in a hepatoma cell line
-
Lohmann V, et al. 1999. Replication of subgenomic hepatitis C virus RNAs in a hepatoma cell line. Science 285:110-113.
-
(1999)
Science
, vol.285
, pp. 110-113
-
-
Lohmann, V.1
-
23
-
-
5044222992
-
Introduction of NS5A mutations enables sub-genomic HCV replicon derived from chimpanzee-infectious HC-J4 iso-late to replicate efficiently in Huh-7 cells
-
Maekawa S, et al. 2004. Introduction of NS5A mutations enables sub-genomic HCV replicon derived from chimpanzee-infectious HC-J4 iso-late to replicate efficiently in Huh-7 cells. J. Viral Hepat. 11:394-403.
-
(2004)
J. Viral Hepat.
, vol.11
, pp. 394-403
-
-
Maekawa, S.1
-
24
-
-
0032547938
-
Interferon alfa-2b alone or in combination with ribavirin as initial treatment for chronic hepatitis C
-
McHutchison JG, et al. 1998. Interferon alfa-2b alone or in combination with ribavirin as initial treatment for chronic hepatitis C. N. Engl. J. Med. 339:1485-1492.
-
(1998)
N. Engl. J. Med.
, vol.339
, pp. 1485-1492
-
-
Mchutchison, J.G.1
-
25
-
-
84885297194
-
-
Co., Merck & Co., Whitehouse Station, NJ
-
Merck & Co. 2011. Victrelis (boceprevir) prescribing information. Merck & Co., Whitehouse Station, NJ. http://www.accessdata.fda.gov/drugsatfda_docs/label/2011/202258lbl.pdf.
-
(2011)
Victrelis (boceprevir) prescribing information
-
-
Merck, M.1
-
26
-
-
34547119906
-
The NS3 helicase and NS5B-to-3=X regions are important for efficient hepatitis C virus strain JFH-1 replication in Huh7 cells
-
Murayama A, et al. 2007. The NS3 helicase and NS5B-to-3=X regions are important for efficient hepatitis C virus strain JFH-1 replication in Huh7 cells. J. Virol. 81:8030-8040.
-
(2007)
J. Virol.
, vol.81
, pp. 8030-8040
-
-
Murayama, A.1
-
27
-
-
77954053980
-
RNA polymerase activity and specific RNA structure are required for efficient HCV replication in cultured cells
-
doi:10.1371/journal.ppat.1000885
-
Murayama A, et al. 2010. RNA polymerase activity and specific RNA structure are required for efficient HCV replication in cultured cells. PLoS Pathog. 6:e1000885. doi:10.1371/journal.ppat.1000885.
-
(2010)
PLoS Pathog.
, vol.6
-
-
Murayama, A.1
-
28
-
-
0036196022
-
Persistent and transient replication of full- length hepatitis C virus genomes in cell culture
-
Pietschmann T, et al. 2002. Persistent and transient replication of full- length hepatitis C virus genomes in cell culture. J. Virol. 76:4008-4021.
-
(2002)
J. Virol.
, vol.76
, pp. 4008-4021
-
-
Pietschmann, T.1
-
29
-
-
67650882702
-
Production of infectious genotype 1b virus particles in cell culture and impairment by replication enhancing muta-tions
-
doi:10.1371/journal.ppat.1000475
-
Pietschmann T, et al. 2009. Production of infectious genotype 1b virus particles in cell culture and impairment by replication enhancing muta-tions. PLoS Pathog. 5:e1000475. doi:10.1371/journal.ppat.1000475.
-
(2009)
PLoS Pathog.
, vol.5
-
-
Pietschmann, T.1
-
30
-
-
0032585237
-
Randomised trial of interferon Universal-GreekwithMathPi.-1.H92512b plus ribavirin for 48 weeks or for 24 weeks versus interferon Universal-GreekwithMathPi.-1.H92512b plus placebo for 48 weeks for treatment of chronic infection with hepatitis C virus
-
Poynard T, et al. 1998. Randomised trial of interferon Universal-GreekwithMathPi.-1.H92512b plus ribavirin for 48 weeks or for 24 weeks versus interferon Universal-GreekwithMathPi.-1.H92512b plus placebo for 48 weeks for treatment of chronic infection with hepatitis C virus. Lancet 352:1426-1432.
-
(1998)
Lancet.
, vol.352
, pp. 1426-1432
-
-
Poynard, T.1
-
31
-
-
71549163465
-
Evaluation of hepatitis C virus core antigen assays in detecting recombinant viral antigens of various genotypes
-
Saeed M, et al. 2009. Evaluation of hepatitis C virus core antigen assays in detecting recombinant viral antigens of various genotypes. J. Clin. Micro-biol. 47:4141-4143.
-
(2009)
J. Clin. Micro-biol.
, vol.47
, pp. 4141-4143
-
-
Saeed, M.1
-
32
-
-
77952103879
-
Biological properties of purified recombinant HCV particles with an epitope-tagged envelope
-
Takahashi H, et al. 2010. Biological properties of purified recombinant HCV particles with an epitope-tagged envelope. Biochem. Biophys. Res. Commun. 395:565-571.
-
(2010)
Biochem. Biophys. Res. Commun.
, vol.395
, pp. 565-571
-
-
Takahashi, H.1
-
33
-
-
4344574035
-
Near completely humanized liver in mice shows human-type metabolic responses to drugs
-
Tateno C, et al. 2004. Near completely humanized liver in mice shows human-type metabolic responses to drugs. Am. J. Pathol. 165:901-912.
-
(2004)
Am. J. Pathol.
, vol.165
, pp. 901-912
-
-
Tateno, C.1
-
36
-
-
84870671204
-
Vertex Pharmaceuticals
-
Vertex Pharmaceuticals, Cambridge, MA
-
Vertex Pharmaceuticals. 2011. Incivek (telaprevir) prescribing informa-tion. Vertex Pharmaceuticals, Cambridge, MA. http://www.accessdata.fda.gov/drugsatfda_docs/label/2011/201917lbl.pdf.
-
(2011)
Incivek (telaprevir) prescribing informa-tion
-
-
-
37
-
-
61549088814
-
Isolation of JFH-1 strain and development of an HCV infection system
-
Wakita T. 2009. Isolation of JFH-1 strain and development of an HCV infection system. Methods Mol. Biol. 510:305-327.
-
(2009)
Methods Mol. Biol.
, vol.510
, pp. 305-327
-
-
Wakita, T.1
-
38
-
-
22544470874
-
Production of infectious hepatitis C virus in tissue culture from a cloned viral genome
-
Wakita T, et al. 2005. Production of infectious hepatitis C virus in tissue culture from a cloned viral genome. Nat. Med. 11:791-796.
-
(2005)
Nat. Med.
, vol.11
, pp. 791-796
-
-
Wakita, T.1
-
39
-
-
0030740520
-
Transcripts from a single full-length cDNA clone of hepatitis C virus are infectious when directly transfected into the liver of a chimpanzee
-
U. S. A.
-
Yanagi M, Purcell RH, Emerson SU, Bukh J. 1997. Transcripts from a single full-length cDNA clone of hepatitis C virus are infectious when directly transfected into the liver of a chimpanzee. Proc. Natl. Acad. Sci. U. S. A. 94:8738-8743.
-
(1997)
Proc. Natl. Acad. Sci.
, vol.94
, pp. 8738-8743
-
-
Yanagi, M.1
Purcell, R.H.2
Emerson, S.U.3
Bukh, J.4
-
40
-
-
0033568548
-
Hepatitis C virus: An infectious molecular clone of a second major genotype (2a) and lack of viability of intertypic 1a and 2a chimeras
-
Yanagi M, Purcell RH, Emerson SU, Bukh J. 1999. Hepatitis C virus: an infectious molecular clone of a second major genotype (2a) and lack of viability of intertypic 1a and 2a chimeras. Virology 262:250-263.
-
(1999)
Virology.
, vol.262
, pp. 250-263
-
-
Yanagi, M.1
Purcell, R.H.2
Emerson, S.U.3
Bukh, J.4
-
41
-
-
21544440397
-
Robust hepatitis C virus infection in vitro
-
U. S. A.
-
Zhong JP, et al. 2005. Robust hepatitis C virus infection in vitro. Proc. Natl. Acad. Sci. U. S. A. 102:9294-9299.
-
(2005)
Proc. Natl. Acad. Sci.
, vol.102
, pp. 9294-9299
-
-
Zhong, J.P.1
|