Infectious hepatitis C virus pseudo-particles containing functional E1-E2 envelope protein complexes

Journal of Experimental Medicine

Volumn 197, Issue 5, 2003, Pages 633-642

  Bartosch, Birke ^a   Dubuisson, Jean ^b   Cosset, François Loïc ^a  

^a UNIVERSITÉ DE LYON   (France)

^b INSTITUT PASTEUR DE LILLE   (France)

Author keywords

Glycoproteins; Hepatitis; Neutralization; Receptor; Viral assembly

Indexed keywords

CD81 ANTIGEN; E2 PROTEIN; ENVELOPE PROTEIN; GLYCOPROTEIN; GLYCOPROTEIN E1; GREEN FLUORESCENT PROTEIN; MONOCLONAL ANTIBODY; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ANIMAL CELL; ARTICLE; CELL LINE; CONTROLLED STUDY; DRUG TARGETING; HEPATITIS C; HUMAN; HUMAN CELL; LENTIVIRINAE; LIVER CELL; MARKER GENE; NONHUMAN; PRIORITY JOURNAL; RETROVIRUS; SERUM; VIRUS PARTICLE;

ANIMALS; ANTIGENS, CD; CELLS, CULTURED; GENES, REPORTER; HEPACIVIRUS; HEPATITIS C; HEPATITIS C ANTIGENS; HEPATOCYTES; HUMANS; MEMBRANE PROTEINS; NEUTRALIZATION TESTS; RECEPTORS, LDL; RECOMBINANT FUSION PROTEINS; TUMOR CELLS, CULTURED; VIRAL ENVELOPE PROTEINS; VIRAL STRUCTURAL PROTEINS; VIRION; VIRUS ASSEMBLY;

EID: 0037416146     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.20021756     Document Type: Article

References (48)

1. Lavanchy, D., R. Purcell, F.B. Hollinger, C. Howard, A. Alberti, M. Kew, G. Dusheiko, M. Alter, E. Ayoola, P. Beutels, et al. 1999. Global surveillance and control of hepatitis C. J. Viral Hepat. 6:35-47.
2. Dieterich, D.T. 2002. Treatment of hepatitis C and anemia in human immunodeficiency virus-infected patients. J. Infect. Dis. 185:S128-137.
3. Lindenbach, B.D., and C.M. Rice. 2001. Flaviviridae: the viruses and their replication. In Fields Virology, 4th ed. D.M. Knipe and P.M. Howley, editors. Lippincott Williams & Wilkins, Philadelphia. 991-1042.
4. Blight, K.J., A.A. Kolykhalov, and C.M. Rice. 2000. Efficient initiation of HCV RNA replication in cell culture. Science. 290:1972-1974.
5. Lohmann, V., F. Korner, J. Koch, U. Herian, L. Theilmann, and R. Bartenschlager. 1999. Replication of subgenomic hepatitis C virus RNAs in a hepatoma cell line. Science. 285:110-113.
6. Pietschmann, T., V. Lohmann, A. Kaul, N. Krieger, G. Rinck, G. Rutter, D. Strand, and R. Bartenschlager. 2002. Persistent and transient replication of full-length hepatitis C virus genomes in cell culture. J. Virol. 76:4008-4021.
7. Baumert, T.F., S. Ito, D.T. Wong, and T.J. Liang. 1998. Hepatitis C virus structural proteins assemble into viruslike particles in insect cells. J. Virol. 72:3827-3836.
8. Buonocore, L., K.J. Blight, C.M. Rice, and J.K. Rose. 2002. Characterization of vesicular stomatitis virus recombinants that express and incorporate high levels of hepatitis C virus glycoproteins. J. Virol. 76:6865-6872.
9. Flint, M., J.M. Thomas, C.M. Maidens, C. Shotton, S. Levy, W.S. Barclay, and J.A. McKeating. 1999. Functional analysis of cell surface-expressed hepatitis C virus E2 glycoprotein. J. Virol. 73:6782-6790.
10. Lagging, L.M., K. Meyer, R.J. Owens, and R. Ray. 1998. Functional role of hepatitis C virus chimeric glycoproteins in the infectivity of pseudotyped virus. J. Virol. 72:3539-3546.
11. Nègre, D., P. Mangeot, G. Duisit, S. Blanchard, P. Vidalain, P. Leissner, A. Winter, C. Rabourdin-Combe, M. Mehtali, P. Moullier, et al. 2000. Characterization of novel safe lentiviral vectors derived from simian immunodeficiency virus (SIVmac251) that efficiently transduce mature human dendritic cells. Gene Ther. 7:1613-1623.
12. Op De Beeck, A., R. Montserret, S. Duvet, L. Cocquerel, R. Cacan, B. Barberot, M. Le Maire, F. Penin, and J. Dubuisson. 2000. The transmembrane domains of hepatitis C virus envelope glycoproteins E1 and E2 play a major role in heterodimerization. J. Biol. Chem. 275:31428-31437.
13. Naldini, L., U. Blömer, P. Gallay, D. Ory, R. Mulligan, F.H. Gage, I.M. Verma, and D. Trono. 1996. In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector. Science. 272:263-267.
14. Maurice, M., E. Verhoeyen, P. Salmon, D. Trono, S.J. Russell, and F.-L. Cosset. 2002. Efficient gene transfer into human primary blood lymphocytes by surface-engineered lentiviral vectors that display a T cell-activating polypeptide. Blood. 99:2342-2350.
15. Sandrin, V., B. Boson, P. Salmon, W. Gay, D. Nègre, R.L. Grand, D. Trono, and F.-L. Cosset. 2002. Lentiviral vectors pseudotyped with a modified RD114 envelope glycoprotein show increased stability in sera and augmented transduction of primary lymphocytes and CD34+ cells derived from human and non-human primates. Blood. 100:823-832.
16. Nakabayashi, H., K. Taketa, K. Miyano, T. Yamane, and J. Sato. 1982. Growth of human hepatoma cells lines with differentiated functions in chemically defined medium. Cancer Res. 42:3858-3863.
17. Bartenschlager, R., and V. Lohmann. 2000. Replication of hepatitis C virus. J. Gen. Virol. 81:1631-1648.
18. Dubuisson, J. 2000. Folding, assembly and subcellular localization of hepatitis C virus glycoproteins. Curr. Top. Microbiol. Immunol. 242:135-148.
19. Op De Beeck, A., L. Cocquerel, and J. Dubuisson. 2001. Biogenesis of hepatitis C virus envelope glycoproteins. J. Gen. Virol. 82:2589-2595.
20. Zein, N.N. 2000. Clinical significance of hepatitis C virus genotypes. Clin. Microbiol. Rev. 13:223-235.
21. Ott, D.E. 1997. Cellular proteins in HIV virions. Rev. Med. Virol. 7:167-180.
22. Sung, V.M., and M.M. Lai. 2002. Murine retroviral pseudo-type virus containing hepatitis B virus large and small surface antigens confers specific tropism for primary human hepatocytes: a potential liver-specific targeting system. J. Virol. 76:912-917.
23. Nègre, D., G. Duisit, P.-E. Mangeot, P. Moullier, J.-L. Darlix, and F.-L. Cosset. 2002. Lentiviral vectors derived from simian immunodeficiency virus (SIV). Curr. Top. Microbiol. Immunol. 261:53-74.
24. Swanstrom, R., and J.W. Wills. 1997. Synthesis, assembly, and processing of viral proteins. In Retroviruses. J.M. Coffin, S.H. Hughes, and H.E. Varmus, editors. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York. 263-334.
25. Kizhatil, K., A. Gromley, and L.M. Albritton. 2001. Two point mutations produce infectious retrovirus bearing a green fluorescent protein-SU fusion protein. J. Virol. 75:11881-11885.
26. Lavillette, D., A. Ruggieri, B. Boson, M. Maurice, and F.-L. Cosset. 2002. Relationship between SU subdomains that regulate the receptor-mediated transition from the native (fusion-inhibited) and fusion-active conformations of the murine leukemia virus glycoprotein. J. Virol. 76:9685-2002.
27. Nguyen, T.H., J. Oberholzer, J. Birraux, P. Majno, P. Morel, and D. Trono. 2002. Highly efficient lentiviral vector-mediated transduction of nondividing, fully reimplantable primary hepatocytes. Mol. Ther. 6:199-209.
28. Dubuisson, J., H.H. Hsu, R.C. Cheung, H.B. Greenberg, D.G. Russell, and C.M. Rice. 1994. Formation and intracellular localization of hepatitis C virus envelope glycoprotein complexes expressed by recombinant vaccinia and Sindbis viruses. J. Virol. 68:6147-6160.
29. Flint, M., C. Maidens, L.D. Loomis-Price, C. Shotton, J. Dubuisson, P. Monk, A. Higginbottom, S. Levy, and J.A. McKeating. 1999. Characterization of hepatitis C virus E2 glycoprotein interaction with a putative cellular receptor, CD81. J. Virol. 73:6235-6244.
30. Flint, M., J. Dubuisson, C. Maidens, R. Harrop, G.R. Guile, P. Borrow, and J.A. McKeating. 2000. Functional characterization of intracellular and secreted forms of a truncated hepatitis C virus E2 glycoprotein. J. Virol. 74:702-709.
31. Patel, A.H., J. Wood, F. Penin, J. Dubuisson, and J.A. Mc-Keating. 2000. Construction and characterization of chimeric hepatitis C virus E2 glycoproteins: analysis of regions critical for glycoprotein aggregation and CD81 binding. J. Gen. Virol. 81:2873-2883.
32. Agnello, V., G. Abel, M. Elfahal, G.B. Knight, and Q.X. Zhang. 1999. Hepatitis C virus and other flaviviridae viruses enter cells via low density lipoprotein receptor. Proc. Natl. Acad. Sci. USA. 96:12766-12771.
33. Monazahian, M., I. Bohme, S. Bonk, A. Koch, C. Scholz, S. Grethe, and R. Thomssen. 1999. Low density lipoprotein receptor as a candidate receptor for hepatitis C virus. J. Med. Virol. 57:223-229.
34. Pileri, P., Y. Uematsu, S. Campagnoli, G. Galli, F. Falugi, R. Petracca, A.J. Weiner, M. Houghton, D. Rosa, G. Grandi, and S. Abrignani. 1998. Binding of hepatitis C virus to CD81. Science. 282:938-941.
35. Allander, T., X. Forns, S.U. Emerson, R.H. Purcell, and J. Bukh. 2000. Hepatitis C virus envelope protein E2 binds to CD81 of tamarins. Virology. 277:358-367.
36. Andre, P., F. Komurian-Pradel, S. Deforges, M. Perret, J.L. Berland, M. Sodoyer, S. Pol, C. Brechot, G. Paranhos-Baccala, and V. Lotteau. 2002. Characterization of low- and very-low-density hepatitis C virus RNA-containing particles. J. Virol. 76:6919-6928.
37. Meola, A., A. Sbardellati, B. Bruni Ercole, M. Cerretani, M. Pezzanera, A. Ceccacci, A. Vitelli, S. Levy, A. Nicosia, C. Traboni, et al. 2000. Binding of hepatitis C virus E2 glycoprotein to CD81 does not correlate with species permissiveness to infection. J. Virol. 74:5933-5938.
38. Scarselli, E., H. Ansuini, R. Cerino, R. Roccasecca, S. Acali, G. Filocamo, C. Traboni, A. Nicosia, R. Cortese, and A. Vitelli. 2002. The human scavenger receptor class B type I is a novel candidate receptor for the hepatitis C virus. EMBO J. 21:5017-5025.
39. Wellnitz, S., B. Klumpp, H. Barth, S. Ito, E. Depla, J. Dubuisson, H.E. Blum, and T.F. Baumert. 2002. Binding of hepatitis C virus-like particles derived from infectious clone H77C to defined human cell lines. J. Virol. 76:1181-1193.
40. Triyatni, M., B. Saunier, P. Maruvada, A.R. Davis, L. Ulianich, T. Heller, A. Patel, L.D. Kohn, and T.J. Liang. 2002. Interaction of hepatitis C virus-like particles and cells: a model system for studying viral binding and entry. J. Virol. 76:9335-9344.
41. Owsianka, A., R.F. Clayton, L.D. Loomis-Price, J.A. Mc-Keating, and A.H. Patel. 2001. Functional analysis of hepatitis C virus E2 glycoproteins and virus-like particles reveals structural dissimilarities between different forms of E2. J. Gen. Virol. 82:1877-1883.
42. Matsuura, Y., H. Tani, K. Suzuki, T. Kimura-Someya, R. Suzuki, H. Aizaki, K. Ishii, K. Moriishi, C.S. Robison, M.A. Whitt, and T. Miyamura. 2001. Characterization of pseudo-type VSV possessing HCV envelope proteins. Virology. 286:263-275.
43. Rose, N.F., P.A. Marx, A. Luckay, D.F. Nixon, W.J. Moretto, S.M. Donahoe, D. Montefiori, A. Roberts, L. Buonocore, and J.K. Rose. 2001. An effective AIDS vaccine based on live attenuated vesicular stomatitis virus recombinants. Cell. 106:539-549.
44. Haywood, A. 1994. Virus receptors: binding, adhesion strengthening, and changes in viral structure. J. Virol. 68:1-5.
45. Klasse, P.J., R. Bron, and M. Marsh. 1998. Mechanisms of enveloped virus entry into animal cells. Adv. Drug Deliv. Rev. 34:65-91.
46. Cocquerel, L., A, Op de Beeck, M. Lambot, J. Roussel, D. Delgrange, A. Pillez, C. Wychowski, F. Penin, and J. Dubuisson. 2002. Topologic changes in the transmembrane domains of hepatitis C virus envelope glycoproteins. EMBO J. 21:2893-2902.
47. Cocquerel, L., J.-C. Meunier, A. Pillez, C. Wychowski, and J. Dubuisson. 1998. A retention signal necessary and sufficient for endoplasmic reticulum localization maps to the transmembrane domain of hepatitis C virus glycoprotein E2. J. Virol. 72:2183-2191.
48. Abe, A., S.T. Chen, A. Miyanohara, and T. Friedmann. 1998. In vitro cell-free conversion of noninfectious Moloney retrovirus particles to an infectious form by the addition of the vesicular stomatitis virus surrogate envelope G protein. J. Virol. 72:6356-6361.