Immunization with a Recombinant Vaccinia Virus That Encodes Nonstructural Proteins of the Hepatitis C Virus Suppresses Viral Protein Levels in Mouse Liver

PLoS ONE

Volumn 7, Issue 12, 2012, Pages

  Sekiguchi, Satoshi ^a   Kimura, Kiminori ^b   Chiyo, Tomoko ^a   Ohtsuki, Takahiro ^a   Tobita, Yoshimi ^a   Tokunaga, Yuko ^a   Yasui, Fumihiko ^a   Tsukiyama Kohara, Kyoko ^c   Wakita, Takaji ^d   Tanaka, Toshiyuki ^e   Miyasaka, Masayuki ^f   Mizuno, Kyosuke ^g   Hayashi, Yukiko ^b   Hishima, Tsunekazu ^b   Matsushima, Kouji ^h   Kohara, Michinori ^a  

^a TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

^b TOKYO METROPOLITAN KOMAGOME HOSPITAL   (Japan)

^c KAGOSHIMA UNIVERSITY   (Japan)

^d NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

^e HYOGO COLLEGE OF MEDICINE   (Japan)

^f OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^g Kaketsuken   (Japan)

^h UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CORE PROTEIN; GLYCOGEN; INTERLEUKIN 6; POLYINOSINIC POLYCYTIDYLIC ACID; TUMOR NECROSIS FACTOR ALPHA; VACCINIA VACCINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ANTIVIRAL ACTIVITY; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; DRUG EFFICACY; FATTY LIVER; GLYCOGEN METABOLISM; HEPATITIS C; HEPATITIS C VIRUS; IMMUNIZATION; LIVER CELL CARCINOMA; LIVER FIBROSIS; LIVER LEVEL; MOUSE; NONHUMAN; ONSET AGE; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; VACCINIA VIRUS; VIRUS RECOMBINANT; VIRUS STRAIN;

ANIMALS; CARCINOMA, HEPATOCELLULAR; CYTOKINES; END STAGE LIVER DISEASE; FEMALE; GENE EXPRESSION REGULATION, VIRAL; HEPACIVIRUS; HEPATITIS C, CHRONIC; HUMANS; IMMUNIZATION; IMMUNOENZYME TECHNIQUES; LIVER NEOPLASMS, EXPERIMENTAL; MICE; MICE, TRANSGENIC; RECOMBINANT PROTEINS; T-LYMPHOCYTES, CYTOTOXIC; VACCINIA VIRUS; VIRAL CORE PROTEINS; VIRAL HEPATITIS VACCINES; VIRAL NONSTRUCTURAL PROTEINS;

HEPATITIS C VIRUS; MUS; VACCINIA VIRUS;

EID: 84871333031     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0051656     Document Type: Article

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