Hepatitis C virus core and E2 protein expression in transgenic mice

Hepatology

Volumn 25, Issue 3, 1997, Pages 719-727

  Pasquinelli, Claudio ^a   Shoenberger, Jan M ^a   Chung, Josan ^a   Chang, Kyong M I ^a   Guidotti, Luca G ^a   Selby, Mark ^b   Berger, Kim ^b   Lesniewski, Richard ^c   Houghton, Michael ^b   Chisari, Francis V ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b NOVARTIS PHARMA AG   (Switzerland)

^c ABBOTT LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN; CORE PROTEIN; VIRUS ENVELOPE PROTEIN;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL STRAIN 3T3; CELL TRANSFORMATION; CONTROLLED STUDY; CYTOPLASM; HEPATITIS C VIRUS; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOPATHOLOGY; LIVER BIOPSY; LIVER CELL DAMAGE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; RAT; TRANSCRIPTION REGULATION; TRANSGENIC MOUSE;

ANIMALS; BLOTTING, NORTHERN; GENE EXPRESSION REGULATION, VIRAL; HUMANS; LIVER; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; POLYMERASE CHAIN REACTION; RNA, VIRAL; TRANSCRIPTION, GENETIC; VIRAL CORE PROTEINS; VIRAL ENVELOPE PROTEINS; VIRUS REPLICATION;

EID: 0031057659     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1002/hep.510250338     Document Type: Article

References (11)

1. Choo Q-L, Kuo G, Weiner AJ, Overby LR, Bradley DW, Houghton M. Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome. Science 1989;244:359-362.
2. Alter MJ, Margolis HS, Krawczynski K, Judson FN, Mares A, Alexander WJ, Hu PY, et al. The natural history of community-acquired hepatitis C in the United States. N Engl J Med 1992;327:1899-1905.
3. Weiner AJ, Kuo G, Bradley DW, Bonino F, Saracco G, Lee C, Rosenblatt J, et al. Detection of hepatitis C virus sequences in non-A, non-B hepatitis. Lancet 1990;335:1-3.
4. Seeff LB, Buskell-Bales Z, Wright EC, Durako SJ, Alter HJ, Iber FL, Hollinger FB, et al. Long-term mortality after transfusion-associated non-A, non-B hepatitis. N Engl J Med 1992;327:1906-1911.
5. Choo Q-L, Richman KH, Han JH, Berger K, Lee C, Dong C, Gallegos C, et al. Genetic organization and diversity of the hepatitis C virus. Proc Natl Acad Sci U S A 1991;88:2451-2455.
6. Ogata N, Alter HJ, Miller RH, Purcell RH. Nucleotide sequence and mutation rate of the H strain of hepatitis C virus. Proc Natl Acad Sci USA 1991;88:3392-3396.
7. Takamizawa A, Mori C, Fuke I, Manabe S, Murakami S, Fujita J, Onishi E, et al. Structure and organization of the hepatitis C virus genome isolated from human carriers. J Virol 1991;65:1105-1113.
8. Kato N, Hijikata M, Ootsuyama Y, Nakagawa M, Ohkoshi S, Sugimura T, Shimotohno K. Molecular cloning of the human hepatitis C virus genome from Japanese patients with non-A, non-B hepatitis. Proc Natl Acad Sci USA 1990;87:9524-9528.
9. Grakoui A, McCourt DW, Wychowski C, Feinstone SM, Rice CM. Characterization of the hepatitis C virus-encoded serine proteinase: determination of proteinase-dependent polyprotein cleavage sites. J Virol 1993;67: 2832-2843.
10. Grakoui A, Wychowski C, Lin C, Feinstone SM, Rice CM. Expression and identification of hepatitis C virus polyprotein cleavage products. J Virol 1993;67:1385-1395.
11. Hijikata M, Kato N, Ootsuyama Y, Nakagawa M, Shimotohno K. Gene mapping of the putative structural region of the hepatitis C virus genome by in vitro processing analysis. Proc Natl Acad Sci U S A 1991;88:5547-5551.