Hesperidin Alleviates Cognitive Impairment, Mitochondrial Dysfunction and Oxidative Stress in a Mouse Model of Alzheimer’s Disease

Cellular and Molecular Neurobiology

Volumn 34, Issue 8, 2014, Pages 1209-1221

  Wang, Dongmei ^a   Liu, Ling ^a   Zhu, Xiaoying ^a   Wu, Wenlan ^a   Wang, Yong ^a  

^a HENAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

APPswe PS1dE9 mice; Cognitive ability; Hesperidin; Oxidative stress

Indexed keywords

AMYLOID BETA PROTEIN; CYTOCHROME C OXIDASE; DONEPEZIL; GLYCOGEN SYNTHASE KINASE 3BETA; HESPERIDIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); SUCCINATE DEHYDROGENASE (UBIQUINONE); UBIQUINOL CYTOCHROME C REDUCTASE; AMYLOID PRECURSOR PROTEIN; ANTIOXIDANT; GLUTATHIONE; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3 BETA; HYDROGEN PEROXIDE; MALONALDEHYDE; PRESENILIN 1;

ALZHEIMER DISEASE; AMNESIA; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BRAIN HOMOGENATE; COGNITION; COGNITIVE DEFECT; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DRUG EFFICACY; DRUG MEGADOSE; ENZYME ACTIVITY; ENZYME INHIBITION; LEARNING DISORDER; LOCOMOTION; LOW DRUG DOSE; MALE; MOUSE; NONHUMAN; NOVEL OBJECT RECOGNITION TEST; OXIDATIVE STRESS; PROTEIN PHOSPHORYLATION; TRANSGENIC MOUSE; TREATMENT DURATION; WILD TYPE; ANIMAL; ANIMAL BEHAVIOR; ANTAGONISTS AND INHIBITORS; BRAIN; C57BL MOUSE; COGNITION DISORDERS; COMPLICATION; DISEASE MODEL; DRUG EFFECTS; ENZYMOLOGY; EXPLORATORY BEHAVIOR; MEMORY; METABOLISM; MITOCHONDRION; PATHOLOGY; PATHOPHYSIOLOGY;

MUS;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; ANTIOXIDANTS; BEHAVIOR, ANIMAL; BRAIN; COGNITION DISORDERS; DISEASE MODELS, ANIMAL; EXPLORATORY BEHAVIOR; GLUTATHIONE; GLYCOGEN SYNTHASE KINASE 3; HESPERIDIN; HYDROGEN PEROXIDE; MALONDIALDEHYDE; MEMORY; MICE, INBRED C57BL; MICE, TRANSGENIC; MITOCHONDRIA; OXIDATIVE STRESS; PRESENILIN-1;

EID: 84912051590     PISSN: 02724340     EISSN: 15736830     Source Type: Journal    
DOI: 10.1007/s10571-014-0098-x     Document Type: Article

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