메뉴 건너뛰기




Volumn 956, Issue 2, 2002, Pages 202-210

IMPY: An improved thioflavin-T derivative for in vivo labeling of β-amyloid plaques

Author keywords

Alzheimer's disease imaging agent; Amyloid plaque; Autoradiography; Radioiodinated probe; SPECT imaging

Indexed keywords

6 IODO 2 (4' DIMETHYLAMINO)PHENYLIMIDAZO[1,2 A]PYRIDINE I 123; 6 IODO 2 (4' DIMETHYLAMINO)PHENYLIMIDAZO[1,2 A]PYRIDINE I 125; AMYLOID BETA PROTEIN; FLUORESCENT DYE; HYDROGEN PEROXIDE; PYRIDINE DERIVATIVE; THIOFLAVINE; UNCLASSIFIED DRUG;

EID: 0037195577     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(02)03436-4     Document Type: Article
Times cited : (202)

References (36)
  • 1
    • 0035893245 scopus 로고    scopus 로고
    • Binding characteristics of radiofluorinated 6-dialkylamino-2-naphthylethylidene derivatives as positron emission tomography imaging probes for beta-amyloid plaques in Alzheimer's disease
    • Agdeppa E.D., Kepe V., Liu J., Flores-Torres S., Satyamurthy N., Petric A., Cole G.M., Small G.W., Huang S.C., Barrio J.R. Binding characteristics of radiofluorinated 6-dialkylamino-2-naphthylethylidene derivatives as positron emission tomography imaging probes for beta-amyloid plaques in Alzheimer's disease. J. Neurosci. 21:2001;189.
    • (2001) J. Neurosci. , vol.21 , pp. 189
    • Agdeppa, E.D.1    Kepe, V.2    Liu, J.3    Flores-Torres, S.4    Satyamurthy, N.5    Petric, A.6    Cole, G.M.7    Small, G.W.8    Huang, S.C.9    Barrio, J.R.10
  • 6
    • 0032417251 scopus 로고    scopus 로고
    • Transgenic mice expressing Alzheimer amyloid precursor proteins
    • Hsiao K. Transgenic mice expressing Alzheimer amyloid precursor proteins. Exp. Gerontol. 33:1998;883-889.
    • (1998) Exp. Gerontol. , vol.33 , pp. 883-889
    • Hsiao, K.1
  • 7
    • 0001387952 scopus 로고
    • Small-molecule beta-amyloid probes which distinguish homogenates of Alzheimer's and control brains
    • Klunk W.E., Debnath M.L., Pettegrew J.W. Small-molecule beta-amyloid probes which distinguish homogenates of Alzheimer's and control brains. Biol. Psychiatry. 35:1994;627.
    • (1994) Biol. Psychiatry , vol.35 , pp. 627
    • Klunk, W.E.1    Debnath, M.L.2    Pettegrew, J.W.3
  • 8
    • 0029083059 scopus 로고
    • Chrysamine-G binding to Alzheimer's and control brain: Autopsy study of a new amyloid probe
    • Klunk W.E., Debnath M.L., Pettegrew J.W. Chrysamine-G binding to Alzheimer's and control brain: autopsy study of a new amyloid probe. Neurobiol. Aging. 16:1995;541-548.
    • (1995) Neurobiol. Aging , vol.16 , pp. 541-548
    • Klunk, W.E.1    Debnath, M.L.2    Pettegrew, J.W.3
  • 9
    • 0035902875 scopus 로고    scopus 로고
    • Uncharged thioflavin-T derivatives bind to amyloid-beta protein with high affinity and readily enter the brain
    • Klunk W.E., Wang Y., Huang G.-F., Debnath M.L., Holt D.P., Mathis C.A. Uncharged thioflavin-T derivatives bind to amyloid-beta protein with high affinity and readily enter the brain. Life Sci. 69:2001;1471-1484.
    • (2001) Life Sci. , vol.69 , pp. 1471-1484
    • Klunk, W.E.1    Wang, Y.2    Huang, G.-F.3    Debnath, M.L.4    Holt, D.P.5    Mathis, C.A.6
  • 13
    • 0033625647 scopus 로고    scopus 로고
    • 111In] chelation, conjugation to poly(ethylene glycol)-biotin linkers, and autoradiography with Alzheimer's disease brain sections
    • 111In] chelation, conjugation to poly(ethylene glycol)-biotin linkers, and autoradiography with Alzheimer's disease brain sections. Bioconj. Chem. 11:2000;380-386.
    • (2000) Bioconj. Chem. , vol.11 , pp. 380-386
    • Kurihara, A.1    Pardridge, W.M.2
  • 14
    • 0036173189 scopus 로고    scopus 로고
    • Imaging brain amyloid of Alzheimer disease in vivo in transgenic mice with an Aβ peptide radiopharmaceutical
    • Lee H.J., Zhang Y., Zhu C., Duff K., Pardridge W.M. Imaging brain amyloid of Alzheimer disease in vivo in transgenic mice with an Aβ peptide radiopharmaceutical. J. Cereb. Blood Flow Metab. 22:2002;223-231.
    • (2002) J. Cereb. Blood Flow Metab. , vol.22 , pp. 223-231
    • Lee, H.J.1    Zhang, Y.2    Zhu, C.3    Duff, K.4    Pardridge, W.M.5
  • 15
    • 0029917884 scopus 로고    scopus 로고
    • Regulation of tau phosphorylation in Alzheimer's disease
    • Lee V.M. Regulation of tau phosphorylation in Alzheimer's disease. Ann. NY Acad. Sci. 777:1996;107-113.
    • (1996) Ann. NY Acad. Sci. , vol.777 , pp. 107-113
    • Lee, V.M.1
  • 17
    • 0001732855 scopus 로고    scopus 로고
    • In vivo evaluation and imaging of a lipophilic derivative of Congo Red for amyloid assessment [abstract]
    • Mathis C.A., Holt D.P., Wang Y., Debnath M.L., Bacskai B.J., Hyman B.T., Klunk W.E. In vivo evaluation and imaging of a lipophilic derivative of Congo Red for amyloid assessment [abstract]. J. Nucl. Med. 42:2001;252.
    • (2001) J. Nucl. Med. , vol.42 , pp. 252
    • Mathis, C.A.1    Holt, D.P.2    Wang, Y.3    Debnath, M.L.4    Bacskai, B.J.5    Hyman, B.T.6    Klunk, W.E.7
  • 18
    • 0019061918 scopus 로고
    • LIGAND: A versatile computerized approach for characterization of ligand binding system
    • Munson P.J., Rodbard D. LIGAND: a versatile computerized approach for characterization of ligand binding system. Anal. Biochem. 107:1980;220-239.
    • (1980) Anal. Biochem. , vol.107 , pp. 220-239
    • Munson, P.J.1    Rodbard, D.2
  • 19
    • 0028971069 scopus 로고
    • 125I] labeled beta-amyloid peptide A beta 1-40 through the blood-brain barrier and binding to Alzheimer's disease amyloid of the A beta 1-40/vector complex
    • 125I] labeled beta-amyloid peptide A beta 1-40 through the blood-brain barrier and binding to Alzheimer's disease amyloid of the A beta 1-40/vector complex. Proc. Natl. Acad. Sci. USA. 92:1995;10227-10231.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 10227-10231
    • Saito, Y.1    Buciak, J.2    Yang, J.3    Pardridge, W.M.4
  • 21
    • 0034858025 scopus 로고    scopus 로고
    • The fluorescent Congo Red derivative (trans, trans)-1-bromo-2,5-bis-(3-hydroxycarbony-4-hydroxy)styrylbenzene (BSB) labels diverse β-pleated sheet structures in postmortem human neurodegenerative disease brains
    • Schmidt M.L., Schuck T., Sheridan S., Kung M.-P., Kung H.F., Zhuang Z.-P., Bergeron C., Lamarche J.S., Skovronsky D., Giasson B.I., Lee V.M.-Y., Trojanowski J.Q. The fluorescent Congo Red derivative ( trans, trans )-1-bromo-2,5-bis-(3-hydroxycarbony-4-hydroxy)styrylbenzene (BSB) labels diverse β-pleated sheet structures in postmortem human neurodegenerative disease brains. Am. J. Pathol. 159:2001;937-943.
    • (2001) Am. J. Pathol. , vol.159 , pp. 937-943
    • Schmidt, M.L.1    Schuck, T.2    Sheridan, S.3    Kung, M.-P.4    Kung, H.F.5    Zhuang, Z.-P.6    Bergeron, C.7    Lamarche, J.S.8    Skovronsky, D.9    Giasson, B.I.10    Lee, V.M.-Y.11    Trojanowski, J.Q.12
  • 22
    • 0032211830 scopus 로고    scopus 로고
    • The cell biology of beta-amyloid precursor protein and presenilin in Alzheimer's disease
    • Selkoe D.J. The cell biology of beta-amyloid precursor protein and presenilin in Alzheimer's disease. Trends Cell Biol. 8:1998;447-453.
    • (1998) Trends Cell Biol. , vol.8 , pp. 447-453
    • Selkoe, D.J.1
  • 23
    • 0002680504 scopus 로고    scopus 로고
    • Biology of β-amyloid precursor protein and the mechanism of Alzheimer's disease
    • R.D. Terry, R. Katzman, K.L. Bick, & S.S. Sisodia. Philadelphia: Lippincot/Williams & Wilkins
    • Selkoe D.J. Biology of β-amyloid precursor protein and the mechanism of Alzheimer's disease. Terry R.D., Katzman R., Bick K.L., Sisodia S.S., Alzheimer's Disease. 1999;293-310 Lippincot/Williams & Wilkins, Philadelphia.
    • (1999) Alzheimer's Disease , pp. 293-310
    • Selkoe, D.J.1
  • 24
    • 0033869349 scopus 로고    scopus 로고
    • Imaging Alzheimer's amyloid
    • Selkoe D.J. Imaging Alzheimer's amyloid. Nature Biotechnol. 18:2000;823-824.
    • (2000) Nature Biotechnol. , vol.18 , pp. 823-824
    • Selkoe, D.J.1
  • 25
    • 0035066332 scopus 로고    scopus 로고
    • Alzheimer's disease: Genes, proteins, and therapy
    • Selkoe D.J. Alzheimer's disease: genes, proteins, and therapy. Physiol. Rev. 81:2001;741-766.
    • (2001) Physiol. Rev. , vol.81 , pp. 741-766
    • Selkoe, D.J.1
  • 26
    • 84903202261 scopus 로고    scopus 로고
    • Localization of neurofibrillary tangles and beta-amyloid plaques in the brains of living patients with Alzheimer disease: Binding characteristics of radiofluorinated 6-dialkylamino-2-naphthylethylidene derivatives as positron emission tomography imaging probes for beta-amyloid plaques in Alzheimer's disease
    • Shoghi-Jadid K., Small G.W., Agdeppa E.D., Kepe V., Ercoli L.M., Siddarth P., Read S., Satyamurthy N., Petric A., Huang S.C., Barrio J.R., Liu J., Flores-Torres S., Cole G.M. Localization of neurofibrillary tangles and beta-amyloid plaques in the brains of living patients with Alzheimer disease: Binding characteristics of radiofluorinated 6-dialkylamino-2-naphthylethylidene derivatives as positron emission tomography imaging probes for beta-amyloid plaques in Alzheimer's disease. Am. J. Geriatr. Psychiatry. 10:2002;24-35.
    • (2002) Am. J. Geriatr. Psychiatry , vol.10 , pp. 24-35
    • Shoghi-Jadid, K.1    Small, G.W.2    Agdeppa, E.D.3    Kepe, V.4    Ercoli, L.M.5    Siddarth, P.6    Read, S.7    Satyamurthy, N.8    Petric, A.9    Huang, S.C.10    Barrio, J.R.11    Liu, J.12    Flores-Torres, S.13    Cole, G.M.14
  • 27
    • 0033613129 scopus 로고    scopus 로고
    • Cellular mechanisms of beta-amyloid production and secretion
    • Sinha S., Lieberburg I. Cellular mechanisms of beta-amyloid production and secretion. Proc. Natl. Acad. Sci. USA. 96:1999;11049-11053.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 11049-11053
    • Sinha, S.1    Lieberburg, I.2
  • 29
    • 0033857342 scopus 로고    scopus 로고
    • X-34, a fluorescent derivative of Congo Red: A novel histochemical stain for Alzheimer's disease pathology
    • Styren S.D., Hamilton R.L., Styren G.C., Klunk W.E. X-34, a fluorescent derivative of Congo Red: a novel histochemical stain for Alzheimer's disease pathology. J. Histochem. Cytochem. 48:2000;1223-1232.
    • (2000) J. Histochem. Cytochem. , vol.48 , pp. 1223-1232
    • Styren, S.D.1    Hamilton, R.L.2    Styren, G.C.3    Klunk, W.E.4
  • 30
  • 33
    • 0030930364 scopus 로고    scopus 로고
    • Drug targeting of a peptide radiopharmaceutical through the primate blood-brain barrier in vivo with a monoclonal antibody to the human insulin receptor
    • Wu D., Yang J., Pardridge W.M. Drug targeting of a peptide radiopharmaceutical through the primate blood-brain barrier in vivo with a monoclonal antibody to the human insulin receptor. J. Clin. Invest. 100:1997;1804-1812.
    • (1997) J. Clin. Invest. , vol.100 , pp. 1804-1812
    • Wu, D.1    Yang, J.2    Pardridge, W.M.3
  • 34
    • 0033614955 scopus 로고    scopus 로고
    • Synthesis and amyloid binding properties of rhenium complexes: Preliminary progress toward a reagent for SPECT imaging of Alzheimer's disease brain
    • Zhen W., Han H., Anguiano M., Lemere C.A., Cho C.G., Lansbury P.T. Jr. Synthesis and amyloid binding properties of rhenium complexes: preliminary progress toward a reagent for SPECT imaging of Alzheimer's disease brain. J. Med. Chem. 42:1999;2805-2815.
    • (1999) J. Med. Chem. , vol.42 , pp. 2805-2815
    • Zhen, W.1    Han, H.2    Anguiano, M.3    Lemere, C.A.4    Cho, C.G.5    Lansbury P.T., Jr.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.