메뉴 건너뛰기




Volumn 312, Issue 4, 2003, Pages 922-929

Divergent roles of GSK3 and CDK5 in APP processing

Author keywords

Alzheimer's disease; Antisense; APP; A ; CDK5; GSK3

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; CELL ENZYME; CYCLIN DEPENDENT KINASE 5; GLYCOGEN SYNTHASE KINASE 3BETA; LITHIUM; LY 379196; ROSCOVITINE;

EID: 0344926464     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2003.11.014     Document Type: Article
Times cited : (117)

References (32)
  • 1
    • 0029892175 scopus 로고    scopus 로고
    • Cerebral amyloid deposition and diffuse plaques in 'normal' aging: Evidence for presymptomatic and very mild Alzheimer's disease
    • Morris J.C., Storandt M., McKeel D.W. Jr., Rubin E.H., Price J.L., Grant E.A., Berg L. Cerebral amyloid deposition and diffuse plaques in 'normal' aging: evidence for presymptomatic and very mild Alzheimer's disease. Neurology. 46:1996;707-719.
    • (1996) Neurology , vol.46 , pp. 707-719
    • Morris, J.C.1    Storandt, M.2    McKeel, D.W.Jr.3    Rubin, E.H.4    Price, J.L.5    Grant, E.A.6    Berg, L.7
  • 2
    • 0034518216 scopus 로고    scopus 로고
    • The genetics and molecular pathology of Alzheimer's disease: Roles of amyloid and the presenilins
    • Selkoe D.J. The genetics and molecular pathology of Alzheimer's disease: roles of amyloid and the presenilins. Neurol. Clin. 18:2000;903-922.
    • (2000) Neurol. Clin. , vol.18 , pp. 903-922
    • Selkoe, D.J.1
  • 3
    • 0031045216 scopus 로고    scopus 로고
    • Physiology and pathology of tau protein kinases in relation to Alzheimer's disease
    • Imahori K., Uchida T. Physiology and pathology of tau protein kinases in relation to Alzheimer's disease. J. Biochem. (Tokyo). 121:1997;179-188.
    • (1997) J. Biochem. (Tokyo) , vol.121 , pp. 179-188
    • Imahori, K.1    Uchida, T.2
  • 7
    • 0033535553 scopus 로고    scopus 로고
    • Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity
    • Wolfe M.S., Xia W., Ostaszewski B.L., Diehl T.S., Kimberly W.T., Selkoe D.J. Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity. Nature. 398:1999;513-517.
    • (1999) Nature , vol.398 , pp. 513-517
    • Wolfe, M.S.1    Xia, W.2    Ostaszewski, B.L.3    Diehl, T.S.4    Kimberly, W.T.5    Selkoe, D.J.6
  • 8
    • 0034534014 scopus 로고    scopus 로고
    • GSK3 beta forms a tetrameric complex with endogenous PS1-CTF/NTF and beta-catenin. Effects of the D257/D385A and FAD-linked mutations
    • Tesco G., Tanzi R.E. GSK3 beta forms a tetrameric complex with endogenous PS1-CTF/NTF and beta-catenin. Effects of the D257/D385A and FAD-linked mutations. Ann. N. Y. Acad. Sci. 920:2000;227-232.
    • (2000) Ann. N. Y. Acad. Sci. , vol.920 , pp. 227-232
    • Tesco, G.1    Tanzi, R.E.2
  • 9
    • 0030035749 scopus 로고    scopus 로고
    • In vitro phosphorylation of the cytoplasmic domain of the amyloid precursor protein by glycogen synthase kinase-3beta
    • Aplin A.E., Gibb G.M., Jacobsen J.S., Gallo J.M., Anderton B.H. In vitro phosphorylation of the cytoplasmic domain of the amyloid precursor protein by glycogen synthase kinase-3beta. J. Neurochem. 67:1996;699-707.
    • (1996) J. Neurochem. , vol.67 , pp. 699-707
    • Aplin, A.E.1    Gibb, G.M.2    Jacobsen, J.S.3    Gallo, J.M.4    Anderton, B.H.5
  • 11
    • 0028295848 scopus 로고
    • Cell cycle-dependent regulation of the phosphorylation and metabolism of the Alzheimer amyloid precursor protein
    • Suzuki T., Oishi M., Marshak D.R., Czernik A.J., Nairn A.C., Greengard P. Cell cycle-dependent regulation of the phosphorylation and metabolism of the Alzheimer amyloid precursor protein. EMBO J. 13:1994;1114-1122.
    • (1994) EMBO J. , vol.13 , pp. 1114-1122
    • Suzuki, T.1    Oishi, M.2    Marshak, D.R.3    Czernik, A.J.4    Nairn, A.C.5    Greengard, P.6
  • 12
    • 0037966577 scopus 로고    scopus 로고
    • Regulation of amyloid precursor protein (APP) phosphorylation and processing by p35/Cdk5 and p25/Cdk5
    • Liu F., Su Y., Li B., Zhou Y., Ryder J., Gonzalez-DeWhitt P., May P.C., Ni B. Regulation of amyloid precursor protein (APP) phosphorylation and processing by p35/Cdk5 and p25/Cdk5. FEBS Lett. 547:2003;193-196.
    • (2003) FEBS Lett. , vol.547 , pp. 193-196
    • Liu, F.1    Su, Y.2    Li, B.3    Zhou, Y.4    Ryder, J.5    Gonzalez-Dewhitt, P.6    May, P.C.7    Ni, B.8
  • 13
    • 0019026208 scopus 로고
    • Glycogen synthase kinase-3 from rabbit skeletal muscle. Separation from cyclic-AMP-dependent protein kinase and phosphorylase kinase
    • Embi N., Rylatt D.B., Cohen P. Glycogen synthase kinase-3 from rabbit skeletal muscle. Separation from cyclic-AMP-dependent protein kinase and phosphorylase kinase. Eur. J. Biochem. 107:1980;519-527.
    • (1980) Eur. J. Biochem. , vol.107 , pp. 519-527
    • Embi, N.1    Rylatt, D.B.2    Cohen, P.3
  • 14
    • 0035477020 scopus 로고    scopus 로고
    • GSK3 takes centre stage more than 20 years after its discovery
    • Frame S., Cohen P. GSK3 takes centre stage more than 20 years after its discovery. Biochem. J. 359:2001;1-16.
    • (2001) Biochem. J. , vol.359 , pp. 1-16
    • Frame, S.1    Cohen, P.2
  • 15
    • 0034817624 scopus 로고    scopus 로고
    • The role of the Cdk5-p35 kinase in neuronal development
    • Paglini G., Caceres A. The role of the Cdk5-p35 kinase in neuronal development. Eur. J. Biochem. 268:2001;1528-1533.
    • (2001) Eur. J. Biochem. , vol.268 , pp. 1528-1533
    • Paglini, G.1    Caceres, A.2
  • 16
    • 0034832115 scopus 로고    scopus 로고
    • Cyclin-dependent protein kinase 5 (Cdk5) and the regulation of neurofilament metabolism
    • Grant P., Sharma P., Pant H.C. Cyclin-dependent protein kinase 5 (Cdk5) and the regulation of neurofilament metabolism. Eur. J. Biochem. 268:2001;1534-1546.
    • (2001) Eur. J. Biochem. , vol.268 , pp. 1534-1546
    • Grant, P.1    Sharma, P.2    Pant, H.C.3
  • 17
    • 0034829801 scopus 로고    scopus 로고
    • The molecular bases of Alzheimer's disease and other neurodegenerative disorders
    • Maccioni R.B., Munoz J.P., Barbeito L. The molecular bases of Alzheimer's disease and other neurodegenerative disorders. Arch. Med. Res. 32:2001;367-381.
    • (2001) Arch. Med. Res. , vol.32 , pp. 367-381
    • MacCioni, R.B.1    Munoz, J.P.2    Barbeito, L.3
  • 18
    • 0034329543 scopus 로고    scopus 로고
    • Phosphorylation of human tau protein by microtubule-associated kinases: GSK3beta and cdk5 are key participants
    • Flaherty D.B., Soria J.P., Tomasiewicz H.G., Wood J.G. Phosphorylation of human tau protein by microtubule-associated kinases: GSK3beta and cdk5 are key participants. J. Neurosci. Res. 62:2000;463-472.
    • (2000) J. Neurosci. Res. , vol.62 , pp. 463-472
    • Flaherty, D.B.1    Soria, J.P.2    Tomasiewicz, H.G.3    Wood, J.G.4
  • 19
    • 0031052339 scopus 로고    scopus 로고
    • Potentiation of GSK-3-catalyzed Alzheimer-like phosphorylation of human tau by cdk5
    • Sengupta A., Wu Q., Grundke-Iqbal I., Iqbal K., Singh T.J. Potentiation of GSK-3-catalyzed Alzheimer-like phosphorylation of human tau by cdk5. Mol. Cell. Biochem. 167:1997;99-105.
    • (1997) Mol. Cell. Biochem. , vol.167 , pp. 99-105
    • Sengupta, A.1    Wu, Q.2    Grundke-Iqbal, I.3    Iqbal, K.4    Singh, T.J.5
  • 22
    • 0035863055 scopus 로고    scopus 로고
    • Age-dependent changes in brain, CSF, and plasma amyloid (beta) protein in the Tg2576 transgenic mouse model of Alzheimer's disease
    • Kawarabayashi T., Younkin L.H., Saido T.C., Shoji M., Ashe K.H., Younkin S.G. Age-dependent changes in brain, CSF, and plasma amyloid (beta) protein in the Tg2576 transgenic mouse model of Alzheimer's disease. J. Neurosci. 21:2001;372-381.
    • (2001) J. Neurosci. , vol.21 , pp. 372-381
    • Kawarabayashi, T.1    Younkin, L.H.2    Saido, T.C.3    Shoji, M.4    Ashe, K.H.5    Younkin, S.G.6
  • 23
    • 0037135111 scopus 로고    scopus 로고
    • The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics
    • Hardy J., Selkoe D.J. The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. Science. 297:2002;353-356.
    • (2002) Science , vol.297 , pp. 353-356
    • Hardy, J.1    Selkoe, D.J.2
  • 24
    • 0025264201 scopus 로고
    • The Alzheimer amyloid precursor protein. Identification of a stable intermediate in the biosynthetic/degradative pathway
    • Oltersdorf T., Ward P.J., Henriksson T., Beattie E.C., Neve R., Lieberburg I., Fritz L.C. The Alzheimer amyloid precursor protein. Identification of a stable intermediate in the biosynthetic/degradative pathway. J. Biol. Chem. 265:1990;4492-4497.
    • (1990) J. Biol. Chem. , vol.265 , pp. 4492-4497
    • Oltersdorf, T.1    Ward, P.J.2    Henriksson, T.3    Beattie, E.C.4    Neve, R.5    Lieberburg, I.6    Fritz, L.C.7
  • 25
    • 0032705583 scopus 로고    scopus 로고
    • The protein kinase C inhibitors bisindolylmaleimide I (GF 109203x) and IX (Ro 31-8220) are potent inhibitors of glycogen synthase kinase-3 activity
    • Hers I., Tavare J.M., Denton R.M. The protein kinase C inhibitors bisindolylmaleimide I (GF 109203x) and IX (Ro 31-8220) are potent inhibitors of glycogen synthase kinase-3 activity. FEBS Lett. 460:1999;433-436.
    • (1999) FEBS Lett. , vol.460 , pp. 433-436
    • Hers, I.1    Tavare, J.M.2    Denton, R.M.3
  • 27
  • 29
    • 0038187674 scopus 로고    scopus 로고
    • GSK-3alpha regulates production of Alzheimer's disease amyloid-beta peptides
    • Phiel C.J., Wilson C.A., Lee V.M., Klein P.S. GSK-3alpha regulates production of Alzheimer's disease amyloid-beta peptides. Nature. 423:2003;435-439.
    • (2003) Nature , vol.423 , pp. 435-439
    • Phiel, C.J.1    Wilson, C.A.2    Lee, V.M.3    Klein, P.S.4
  • 31
    • 0032527597 scopus 로고    scopus 로고
    • Selective deposition of amyloid-beta protein in the entorhinal-dentate projection of a transgenic mouse model of Alzheimer's disease
    • Su Y., Ni B. Selective deposition of amyloid-beta protein in the entorhinal-dentate projection of a transgenic mouse model of Alzheimer's disease. J. Neurosci. Res. 53:1998;177-186.
    • (1998) J. Neurosci. Res. , vol.53 , pp. 177-186
    • Su, Y.1    Ni, B.2
  • 32
    • 0042357237 scopus 로고    scopus 로고
    • Inhibitory phosphorylation of glycogen synthase kinase-3 (GSK-3) in response to lithium. Evidence for autoregulation of GSK-3
    • Zhang F., Phiel C.J., Spece L., Gurvich N., Klein P.S. Inhibitory phosphorylation of glycogen synthase kinase-3 (GSK-3) in response to lithium. Evidence for autoregulation of GSK-3. J. Biol. Chem. 278:2003;33067-33077.
    • (2003) J. Biol. Chem. , vol.278 , pp. 33067-33077
    • Zhang, F.1    Phiel, C.J.2    Spece, L.3    Gurvich, N.4    Klein, P.S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.