Reduction of β-amyloid pathology by celastrol in a transgenic mouse model of Alzheimer's disease

Journal of Neuroinflammation

Volumn 7, Issue , 2010, Pages

  Paris, Daniel ^a   Ganey, Nowell J ^a   Laporte, Vincent ^a   Patel, Nikunj S ^a   Beaulieu Abdelahad, David ^a   Bachmeier, Corbin ^a   March, Amelia ^a   Ait Ghezala, Ghania ^a   Mullan, Michael J ^a  

^a ROSKAMP INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; AMYLOID PRECURSOR PROTEIN; BETA SECRETASE; CELASTROL; I KAPPA B KINASE ALPHA; I KAPPA B KINASE GAMMA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 3; PRESENILIN 1; RAF PROTEIN; ASPARTIC PROTEINASE; BACE1 PROTEIN, HUMAN; CARCINOGEN; CDC37 PROTEIN, MOUSE; CELL CYCLE PROTEIN; CHAPERONE; HEAT SHOCK PROTEIN 90; PHORBOL ESTER; PSEN1 PROTEIN, HUMAN; SECRETASE; TRIPTERINE; TRITERPENE;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL LINE; CONTROLLED STUDY; DOSE RESPONSE; DRUG STRUCTURE; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE MUTATION; IC 50; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; MICROGLIA; MOUSE; NONHUMAN; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; TRANSGENIC MOUSE; WESTERN BLOTTING; ANALYSIS OF VARIANCE; ANIMAL; BRAIN; CHEMISTRY; CRICETULUS; DISEASE MODEL; DRUG EFFECT; GENETIC TRANSFECTION; GENETICS; HAMSTER; HUMAN; METABOLISM; METHODOLOGY; PATHOLOGY; SIGNAL TRANSDUCTION;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ANALYSIS OF VARIANCE; ANIMALS; ASPARTIC ACID ENDOPEPTIDASES; BRAIN; CARCINOGENS; CELL CYCLE PROTEINS; CELL LINE, TRANSFORMED; CRICETINAE; CRICETULUS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME-LINKED IMMUNOSORBENT ASSAY; HSP90 HEAT-SHOCK PROTEINS; HUMANS; MICE; MICE, TRANSGENIC; MOLECULAR CHAPERONES; PHORBOL ESTERS; PRESENILIN-1; SIGNAL TRANSDUCTION; TRANSFECTION; TRITERPENES;

EID: 77950377674     PISSN: None     EISSN: 17422094     Source Type: Journal    
DOI: 10.1186/1742-2094-7-17     Document Type: Article

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