메뉴 건너뛰기




Volumn 13, Issue 4, 2014, Pages 793-810

Oleanane triterpenoids in the prevention and therapy of breast cancer: current evidence and future perspectives

Author keywords

Chemoprevention; Mammary cancer; Oleanolic acid; Synthetic oleananes; Treatment

Indexed keywords

6 [1 (5,6,7,8 TETRAHYDRO 3,5,5,8,8 PENTAMETHYL 2 NAPHTHYL)CYCLOPROPYL]NICOTINIC ACID; ACHYRANTHES FAURIEL EXTRACT; ACHYRANTHOSIDE H; AMOORANIN; AMOORANIN METHYL; BARDOXOLONE; BARDOXOLONE METHYL; BETA AMYRIN; CALENDULA OFFICINALIS EXTRACT; CASPASE 3; CASPASE 9; ERYTHRODIOL; GLEDITSIA SINENSIS EXTRACT; GLOSSOGYNE TENUIFOLIA EXTRACT; HEDERA COLCHICA EXTRACT; HEDERACOLCHISID A; HIBISCUS SYRIACUS EXTRACT; MASLINIC ACID; OLDENLANDIA DIFFUSA EXTRACT; OLEANANE DERIVATIVE; OLEANOLIC ACID; OLEANOLIC ACID DERIVATIVE; PHYSENA MADAGASCARIENSIS EXTRACT; PLACEBO; PLANT EXTRACT; REMANGILONE A; REMANGILONE C; TRITERPENOID; UNCLASSIFIED DRUG; UNINDEXED DRUG; WRIGHTIA TOMENTOSA EXTRACT;

EID: 84912031698     PISSN: 15687767     EISSN: 1572980X     Source Type: Journal    
DOI: 10.1007/s11101-014-9337-5     Document Type: Review
Times cited : (107)

References (126)
  • 1
    • 42349104546 scopus 로고    scopus 로고
    • Triterpenoid CDDO-methyl ester inhibits the Janus-activated kinase-1 (JAK1) → signal transducer and activator of transcription-3 (STAT3) pathway by direct inhibition of JAK1 and STAT3
    • COI: 1:CAS:528:DC%2BD1cXks1Giu7k%3D, PID: 18413761
    • Ahmad R, Raina D, Meyer C, Kufe D (2008) Triterpenoid CDDO-methyl ester inhibits the Janus-activated kinase-1 (JAK1) → signal transducer and activator of transcription-3 (STAT3) pathway by direct inhibition of JAK1 and STAT3. Cancer Res 68:2920–2926
    • (2008) Cancer Res , vol.68 , pp. 2920-2926
    • Ahmad, R.1    Raina, D.2    Meyer, C.3    Kufe, D.4
  • 2
    • 84862167763 scopus 로고    scopus 로고
    • Influence of berry polyphenols on receptor signaling and cell-death pathways: implications for breast cancer prevention
    • COI: 1:CAS:528:DC%2BC38Xhs1Ontr0%3D, PID: 22300613
    • Aiyer HS, Warri AM, Woode DR, Hilakivi-Clarke L, Clarke R (2012) Influence of berry polyphenols on receptor signaling and cell-death pathways: implications for breast cancer prevention. J Agric Food Chem 60:5693–5708
    • (2012) J Agric Food Chem , vol.60 , pp. 5693-5708
    • Aiyer, H.S.1    Warri, A.M.2    Woode, D.R.3    Hilakivi-Clarke, L.4    Clarke, R.5
  • 3
    • 78651102365 scopus 로고    scopus 로고
    • Antioxidant, antiproliferative, and pro-apoptotic capacities of pentacyclic triterpenes found in the skin of olives on MCF-7 human breast cancer cells and their effects on DNA damage
    • COI: 1:CAS:528:DC%2BC3cXhsFClur3N, PID: 21142067
    • Allouche Y, Warleta F, Campos M, Sánchez-Quesada C, Uceda M, Beltrán G, Gaforio JJ (2011) Antioxidant, antiproliferative, and pro-apoptotic capacities of pentacyclic triterpenes found in the skin of olives on MCF-7 human breast cancer cells and their effects on DNA damage. J Agric Food Chem 59:121–130
    • (2011) J Agric Food Chem , vol.59 , pp. 121-130
    • Allouche, Y.1    Warleta, F.2    Campos, M.3    Sánchez-Quesada, C.4    Uceda, M.5    Beltrán, G.6    Gaforio, J.J.7
  • 4
    • 85081455078 scopus 로고    scopus 로고
    • American Cancer Society
    • American Cancer Society (2013) Retrieved from http://www.cancer.org/Cancer/BreastCancer/DetailedGuide/breast-cancer-key-statistics. Accessed 8 Oct 2013
  • 5
    • 34347404259 scopus 로고    scopus 로고
    • Paraliane and pepluane diterpenes as anti-inflammatory agents: first insights in structure-activity relationships
    • COI: 1:CAS:528:DC%2BD2sXnsVKntrY%3D, PID: 17561395
    • Barile E, Fattorusso E, Ialenti A, Ianaro A, Lanzotti V (2007) Paraliane and pepluane diterpenes as anti-inflammatory agents: first insights in structure-activity relationships. Bioorg Med Chem Lett 17:4196–4200
    • (2007) Bioorg Med Chem Lett , vol.17 , pp. 4196-4200
    • Barile, E.1    Fattorusso, E.2    Ialenti, A.3    Ianaro, A.4    Lanzotti, V.5
  • 6
    • 43049145841 scopus 로고    scopus 로고
    • Discovery of a new series of jatrophane and lathyrane diterpenes as potent and specific P-glycoprotein modulators
    • COI: 1:CAS:528:DC%2BD1cXltlSntr4%3D, PID: 18452010
    • Barile E, Borriello M, Di Pietro A, Doreau A, Fattorusso C, Fattorusso E, Lanzotti V (2008) Discovery of a new series of jatrophane and lathyrane diterpenes as potent and specific P-glycoprotein modulators. Org Biomol Chem 6:1756–1762
    • (2008) Org Biomol Chem , vol.6 , pp. 1756-1762
    • Barile, E.1    Borriello, M.2    Di Pietro, A.3    Doreau, A.4    Fattorusso, C.5    Fattorusso, E.6    Lanzotti, V.7
  • 7
    • 0036676754 scopus 로고    scopus 로고
    • In vitro activity of hederacolchisid A1 compared with other saponins from Hedera colchica against proliferation of human carcinoma and melanoma cells
    • COI: 1:CAS:528:DC%2BD38XntVSnsb8%3D, PID: 12221585
    • Barthomeuf C, Debiton E, Mshvildadze V, Kemertelidze E, Balansard G (2002) In vitro activity of hederacolchisid A1 compared with other saponins from Hedera colchica against proliferation of human carcinoma and melanoma cells. Planta Med 68:672–675
    • (2002) Planta Med , vol.68 , pp. 672-675
    • Barthomeuf, C.1    Debiton, E.2    Mshvildadze, V.3    Kemertelidze, E.4    Balansard, G.5
  • 8
    • 84873901776 scopus 로고    scopus 로고
    • Indole compounds against breast cancer: recent developments
    • COI: 1:CAS:528:DC%2BC3sXhslGjurY%3D, PID: 23140282
    • Biersack B, Schobert R (2012) Indole compounds against breast cancer: recent developments. Curr Drug Targets 13:1705–1719
    • (2012) Curr Drug Targets , vol.13 , pp. 1705-1719
    • Biersack, B.1    Schobert, R.2
  • 9
    • 67650297506 scopus 로고    scopus 로고
    • Cancer prevention and treatment with resveratrol: from rodent studies to clinical trials
    • COI: 1:CAS:528:DC%2BC3cXptFOisro%3D
    • Bishayee A (2009) Cancer prevention and treatment with resveratrol: from rodent studies to clinical trials. Cancer Prev Res 2:409–418
    • (2009) Cancer Prev Res , vol.2 , pp. 409-418
    • Bishayee, A.1
  • 10
    • 79955034094 scopus 로고    scopus 로고
    • Triterpenoids as potential agents for the chemoprevention and therapy of breast cancer
    • COI: 1:CAS:528:DC%2BC3MXisVGnurg%3D
    • Bishayee A, Ahmed S, Brankov N, Perloff M (2011) Triterpenoids as potential agents for the chemoprevention and therapy of breast cancer. Front Biosci 16:980–996
    • (2011) Front Biosci , vol.16 , pp. 980-996
    • Bishayee, A.1    Ahmed, S.2    Brankov, N.3    Perloff, M.4
  • 11
    • 84872578889 scopus 로고    scopus 로고
    • Dietary phytochemicals in the chemoprevention and treatment of hepatocellular carcinoma: in vivo evidence, molecular targets, and clinical relevance
    • COI: 1:CAS:528:DC%2BC38XhslaqsrbI, PID: 22873222
    • Bishayee A, Thoppil RJ, Waghray A, Kruse JA, Novotny NA, Darvesh AS (2012) Dietary phytochemicals in the chemoprevention and treatment of hepatocellular carcinoma: in vivo evidence, molecular targets, and clinical relevance. Curr Cancer Drug Targets 12:1191–1232
    • (2012) Curr Cancer Drug Targets , vol.12 , pp. 1191-1232
    • Bishayee, A.1    Thoppil, R.J.2    Waghray, A.3    Kruse, J.A.4    Novotny, N.A.5    Darvesh, A.S.6
  • 12
    • 84879247591 scopus 로고    scopus 로고
    • Chemopreventive effect of a novel oleanane triterpenoid in a chemically induced rodent model of breast cancer
    • COI: 1:CAS:528:DC%2BC3sXkslWrt78%3D, PID: 23404339
    • Bishayee A, Mandal A, Thoppil RJ, Darvesh AS, Bhatia D (2013) Chemopreventive effect of a novel oleanane triterpenoid in a chemically induced rodent model of breast cancer. Int J Cancer 133:1054–1064
    • (2013) Int J Cancer , vol.133 , pp. 1054-1064
    • Bishayee, A.1    Mandal, A.2    Thoppil, R.J.3    Darvesh, A.S.4    Bhatia, D.5
  • 13
    • 68949194441 scopus 로고    scopus 로고
    • Epigallocatechin 3-gallate and green tea catechins: united they work, divided they fail
    • COI: 1:CAS:528:DC%2BC3cXptVSqurc%3D
    • Bode AM, Dong Z (2009) Epigallocatechin 3-gallate and green tea catechins: united they work, divided they fail. Cancer Prev Res 2:514–517
    • (2009) Cancer Prev Res , vol.2 , pp. 514-517
    • Bode, A.M.1    Dong, Z.2
  • 15
    • 46949098149 scopus 로고    scopus 로고
    • Hereditary breast cancer: new genetic developments, new therapeutic avenues
    • COI: 1:CAS:528:DC%2BD1cXot1Wht78%3D, PID: 18575892
    • Campeau PM, Foulkes WD, Tischkowitz MD (2008) Hereditary breast cancer: new genetic developments, new therapeutic avenues. Hum Genet 124:31–42
    • (2008) Hum Genet , vol.124 , pp. 31-42
    • Campeau, P.M.1    Foulkes, W.D.2    Tischkowitz, M.D.3
  • 16
    • 84864941592 scopus 로고    scopus 로고
    • Breast cancer chemoprevention: old and new approaches
    • PID: 22851887
    • Cazzaniga M, Bonanni B (2012) Breast cancer chemoprevention: old and new approaches. J Biomed Biotechnol 2012:985620
    • (2012) J Biomed Biotechnol , vol.2012 , pp. 985620
    • Cazzaniga, M.1    Bonanni, B.2
  • 17
    • 84861986754 scopus 로고    scopus 로고
    • In vitro anti-breast cancer activity of ethanolic extract of Wrightia tomentosa: role of pro-apoptotic effects of oleanolic acid and urosolic acid
    • COI: 1:CAS:528:DC%2BC38XntVWhtL0%3D, PID: 22855944
    • Chakravarti B, Maurya R, Siddiqui JA, Bid HK, Rajendran SM, Yadav PP, Konwar R (2012) In vitro anti-breast cancer activity of ethanolic extract of Wrightia tomentosa: role of pro-apoptotic effects of oleanolic acid and urosolic acid. J Ethnopharmacol 142:72–79
    • (2012) J Ethnopharmacol , vol.142 , pp. 72-79
    • Chakravarti, B.1    Maurya, R.2    Siddiqui, J.A.3    Bid, H.K.4    Rajendran, S.M.5    Yadav, P.P.6    Konwar, R.7
  • 18
    • 77955488394 scopus 로고    scopus 로고
    • Selective concomitant inhibition of mTORC1 and mTORC2 activity in estrogen receptor negative breast cancer cells by BN107 and oleanolic acid
    • COI: 1:CAS:528:DC%2BC3cXosVWhtL0%3D, PID: 20027631
    • Chu R, Zhao X, Griffin C, Staub RE, Shoemaker M, Climent J, Leitman D, Cohen I, Shtivelman E, Fong S (2010) Selective concomitant inhibition of mTORC1 and mTORC2 activity in estrogen receptor negative breast cancer cells by BN107 and oleanolic acid. Int J Cancer 127:1209–1219
    • (2010) Int J Cancer , vol.127 , pp. 1209-1219
    • Chu, R.1    Zhao, X.2    Griffin, C.3    Staub, R.E.4    Shoemaker, M.5    Climent, J.6    Leitman, D.7    Cohen, I.8    Shtivelman, E.9    Fong, S.10
  • 19
    • 27444435484 scopus 로고    scopus 로고
    • Discovery and biological evaluation of the novel naturally occurring diterpene pepluanone as antiinflammatory agent
    • COI: 1:CAS:528:DC%2BD2MXhtVyqsr3I, PID: 16250665
    • Corea G, Fattorusso E, Lanzotti V, Di Meglio P, Maffia P, Grassia G, Ialenti A, Ianaro A (2005) Discovery and biological evaluation of the novel naturally occurring diterpene pepluanone as antiinflammatory agent. J Med Chem 48:7055–7062
    • (2005) J Med Chem , vol.48 , pp. 7055-7062
    • Corea, G.1    Fattorusso, E.2    Lanzotti, V.3    Di Meglio, P.4    Maffia, P.5    Grassia, G.6    Ialenti, A.7    Ianaro, A.8
  • 20
    • 67651177448 scopus 로고    scopus 로고
    • Jatrophane diterpenes from Euphorbia spp. as modulators of multidrug resistance in cancer therapy
    • COI: 1:CAS:528:DC%2BD1MXmtlKntbY%3D
    • Corea G, Di Pietro A, Dumontet C, Fattorusso E, Lanzotti V (2009) Jatrophane diterpenes from Euphorbia spp. as modulators of multidrug resistance in cancer therapy. Phytochem Rev 8:431–447
    • (2009) Phytochem Rev , vol.8 , pp. 431-447
    • Corea, G.1    Di Pietro, A.2    Dumontet, C.3    Fattorusso, E.4    Lanzotti, V.5
  • 21
    • 0036673935 scopus 로고    scopus 로고
    • Histopathological characterization of mammary neoplastic lesions induced with 7,12-dimethylbenz(a)anthracene in the rat: a comparative analysis with human breast tumors
    • PID: 12171489
    • Costa I, Solanas M, Escrich E (2002) Histopathological characterization of mammary neoplastic lesions induced with 7,12-dimethylbenz(a)anthracene in the rat: a comparative analysis with human breast tumors. Arch Pathol Lab Med 126:915–927
    • (2002) Arch Pathol Lab Med , vol.126 , pp. 915-927
    • Costa, I.1    Solanas, M.2    Escrich, E.3
  • 23
    • 0031446103 scopus 로고    scopus 로고
    • Monoterpenes in breast cancer chemoprevention
    • COI: 1:CAS:528:DyaK1cXhtFWmt7Y%3D, PID: 9478274
    • Crowell PL (1997) Monoterpenes in breast cancer chemoprevention. Breast Cancer Res Treat 46:191–197
    • (1997) Breast Cancer Res Treat , vol.46 , pp. 191-197
    • Crowell, P.L.1
  • 24
    • 84875348902 scopus 로고    scopus 로고
    • Oxidative stress associated to dysfunctional adipose tissue: a potential link between obesity, type 2 diabetes mellitus and breast cancer
    • COI: 1:CAS:528:DC%2BC3sXjslWgur0%3D, PID: 23409968
    • Crujeiras AB, Díaz-Lagares A, Carreira MC, Amil M, Casanueva FF (2013) Oxidative stress associated to dysfunctional adipose tissue: a potential link between obesity, type 2 diabetes mellitus and breast cancer. Free Radic Res 47:243–256
    • (2013) Free Radic Res , vol.47 , pp. 243-256
    • Crujeiras, A.B.1    Díaz-Lagares, A.2    Carreira, M.C.3    Amil, M.4    Casanueva, F.F.5
  • 25
    • 84855169753 scopus 로고    scopus 로고
    • The triple-negative subtype: new ideas for the poorest prognosis breast cancer
    • COI: 1:CAS:528:DC%2BC3MXhs1Kisr7N
    • Curigliano G, Goldhirsch A (2011) The triple-negative subtype: new ideas for the poorest prognosis breast cancer. J Natl Cancer Inst 43:108–110
    • (2011) J Natl Cancer Inst , vol.43 , pp. 108-110
    • Curigliano, G.1    Goldhirsch, A.2
  • 27
    • 43149091484 scopus 로고    scopus 로고
    • Mechanisms of combined action of different chemopreventive dietary compounds: a review
    • PID: 18458834
    • de Kok TM, van Breda SG, Manson MM (2008) Mechanisms of combined action of different chemopreventive dietary compounds: a review. Eur J Nutr 47:51–59
    • (2008) Eur J Nutr , vol.47 , pp. 51-59
    • de Kok, T.M.1    van Breda, S.G.2    Manson, M.M.3
  • 29
    • 0032941920 scopus 로고    scopus 로고
    • Remangilones A–C, new cytotoxic triterpenes from Physena madagascariensis
    • COI: 1:CAS:528:DyaK1MXhtlOltb8%3D, PID: 10096861
    • Deng Y, Jiang TY, Sheng S, Tianasoa-Ramamonjy M, Snyder JK (1999) Remangilones A–C, new cytotoxic triterpenes from Physena madagascariensis. J Nat Prod 62:471–476
    • (1999) J Nat Prod , vol.62 , pp. 471-476
    • Deng, Y.1    Jiang, T.Y.2    Sheng, S.3    Tianasoa-Ramamonjy, M.4    Snyder, J.K.5
  • 30
    • 58849152837 scopus 로고    scopus 로고
    • CDDO-Me, a synthetic triterpenoid, inhibits expression of IL-6 and Stat3 phosphorylation in multi-drug resistant ovarian cancer cells
    • COI: 1:CAS:528:DC%2BD1MXhtVegsLs%3D, PID: 18587580
    • Duan Z, Ames RY, Ryan M, Hornicek FJ, Mankin H, Seiden MV (2009) CDDO-Me, a synthetic triterpenoid, inhibits expression of IL-6 and Stat3 phosphorylation in multi-drug resistant ovarian cancer cells. Cancer Chemother Pharmacol 63:681–689
    • (2009) Cancer Chemother Pharmacol , vol.63 , pp. 681-689
    • Duan, Z.1    Ames, R.Y.2    Ryan, M.3    Hornicek, F.J.4    Mankin, H.5    Seiden, M.V.6
  • 32
    • 84887563411 scopus 로고    scopus 로고
    • Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer
    • PID: 24286369
    • Eccles SA, Aboagye EO, Ali S, Anderson AS, Armes J et al (2013) Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer. Breast Cancer Res 15:R92
    • (2013) Breast Cancer Res , vol.15 , pp. R92
    • Eccles, S.A.1    Aboagye, E.O.2    Ali, S.3    Anderson, A.S.4    Armes, J.5
  • 33
    • 78650912735 scopus 로고    scopus 로고
    • Complex interactions between phytochemicals. The multi-target therapeutic concept of phytotherapy
    • COI: 1:CAS:528:DC%2BC3MXkslajurg%3D
    • Efferth T, Koch E (2011) Complex interactions between phytochemicals. The multi-target therapeutic concept of phytotherapy. Curr Drug Target 12:122–132
    • (2011) Curr Drug Target , vol.12 , pp. 122-132
    • Efferth, T.1    Koch, E.2
  • 34
    • 79956065682 scopus 로고    scopus 로고
    • Isolation of biologically active constituents from Moringa peregrina (Forssk.) Fiori. (family: Moringaceae) growing in Egypt
    • COI: 1:CAS:528:DC%2BC3MXhsFGqsrrF, PID: 21716619
    • El-Alfy TS, Ezzat SM, Hegazy AK, Amer AM, Kamel GM (2011) Isolation of biologically active constituents from Moringa peregrina (Forssk.) Fiori. (family: Moringaceae) growing in Egypt. Pharmacogn Mag 7:109–115
    • (2011) Pharmacogn Mag , vol.7 , pp. 109-115
    • El-Alfy, T.S.1    Ezzat, S.M.2    Hegazy, A.K.3    Amer, A.M.4    Kamel, G.M.5
  • 36
    • 60849110549 scopus 로고    scopus 로고
    • Achyranthoside H methyl ester, a novel oleanolic acid saponin derivative from Achyranthes fauriei roots, induces apoptosis in human breast cancer MCF-7 and MDA-MB-453 cells via a caspase activation pathway
    • COI: 1:CAS:528:DC%2BD1MXit1eqtL8%3D, PID: 19132288
    • Fukumura M, Ando H, Hirai Y, Toriizuka K, Ida Y, Kuchino Y (2009) Achyranthoside H methyl ester, a novel oleanolic acid saponin derivative from Achyranthes fauriei roots, induces apoptosis in human breast cancer MCF-7 and MDA-MB-453 cells via a caspase activation pathway. J Nat Med 63:181–188
    • (2009) J Nat Med , vol.63 , pp. 181-188
    • Fukumura, M.1    Ando, H.2    Hirai, Y.3    Toriizuka, K.4    Ida, Y.5    Kuchino, Y.6
  • 37
    • 84883449953 scopus 로고    scopus 로고
    • Dietary phytochemicals in cancer prevention and therapy: a complementary approach with promising perspectives
    • PID: 24032363
    • González-Vallinas M, González-Castejón M, Rodríguez-Casado A, Ramírez de Molina A (2013) Dietary phytochemicals in cancer prevention and therapy: a complementary approach with promising perspectives. Nutr Rev 71:585–599
    • (2013) Nutr Rev , vol.71 , pp. 585-599
    • González-Vallinas, M.1    González-Castejón, M.2    Rodríguez-Casado, A.3    Ramírez de Molina, A.4
  • 38
    • 0030867207 scopus 로고    scopus 로고
    • Cancer chemoprevention and therapy by monoterpenes
    • COI: 1:CAS:528:DyaK2sXls1elsLs%3D, PID: 9255590
    • Gould MN (1997) Cancer chemoprevention and therapy by monoterpenes. Environ Health Perspect 105:977–979
    • (1997) Environ Health Perspect , vol.105 , pp. 977-979
    • Gould, M.N.1
  • 39
    • 84862661308 scopus 로고    scopus 로고
    • Oldenlandia diffusa extracts exert antiproliferative and apoptotic effects on human breast cancer cells through ERα/Sp1-mediated p53 activation
    • COI: 1:CAS:528:DC%2BC38XovVGmu7Y%3D, PID: 22213398
    • Gu G, Barone I, Gelsomino L, Giordano C, Bonofiglio D, Statti G, Menichini F, Catalano S, Andò S (2012) Oldenlandia diffusa extracts exert antiproliferative and apoptotic effects on human breast cancer cells through ERα/Sp1-mediated p53 activation. J Cell Physiol 227:3363–3372
    • (2012) J Cell Physiol , vol.227 , pp. 3363-3372
    • Gu, G.1    Barone, I.2    Gelsomino, L.3    Giordano, C.4    Bonofiglio, D.5    Statti, G.6    Menichini, F.7    Catalano, S.8    Andò, S.9
  • 41
    • 84875225510 scopus 로고    scopus 로고
    • Synthesis and cytotoxicity evaluation of oleanolic acid derivatives
    • COI: 1:CAS:528:DC%2BC3sXjtFGmtLs%3D, PID: 23434227
    • Hao J, Liu J, Wen X, Sun H (2013) Synthesis and cytotoxicity evaluation of oleanolic acid derivatives. Bioorg Med Chem Lett 23:2074–2077
    • (2013) Bioorg Med Chem Lett , vol.23 , pp. 2074-2077
    • Hao, J.1    Liu, J.2    Wen, X.3    Sun, H.4
  • 42
    • 84879215754 scopus 로고    scopus 로고
    • Cancer preventive and curative attributes of plants of the Cactaceae family: a review
    • COI: 1:CAS:528:DC%2BC3sXht1Wlsb%2FM, PID: 23702905
    • Harlev E, Nevo E, Solowey E, Bishayee A (2013) Cancer preventive and curative attributes of plants of the Cactaceae family: a review. Planta Med 79:713–722
    • (2013) Planta Med , vol.79 , pp. 713-722
    • Harlev, E.1    Nevo, E.2    Solowey, E.3    Bishayee, A.4
  • 43
    • 34250659001 scopus 로고    scopus 로고
    • Triterpenoids isolated from apple peels have potent antiproliferative activity and may be partially responsible for apple’s anticancer activity
    • COI: 1:CAS:528:DC%2BD2sXkvFKmuro%3D, PID: 17488026
    • He X, Liu RH (2007) Triterpenoids isolated from apple peels have potent antiproliferative activity and may be partially responsible for apple’s anticancer activity. J Agric Food Chem 55:4366–4370
    • (2007) J Agric Food Chem , vol.55 , pp. 4366-4370
    • He, X.1    Liu, R.H.2
  • 44
    • 4544277618 scopus 로고    scopus 로고
    • Design, synthesis and biological evaluation of biotin conjugates of 2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid for the isolation of the protein targets
    • COI: 1:CAS:528:DC%2BD2cXmslSqt70%3D, PID: 15369396
    • Honda T, Janosik T, Honda Y, Han J, Liby KT, Williams CR, Couch RD, Anderson AC, Sporn MB, Gribble GW (2004) Design, synthesis and biological evaluation of biotin conjugates of 2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid for the isolation of the protein targets. J Med Chem 47:4923–4932
    • (2004) J Med Chem , vol.47 , pp. 4923-4932
    • Honda, T.1    Janosik, T.2    Honda, Y.3    Han, J.4    Liby, K.T.5    Williams, C.R.6    Couch, R.D.7    Anderson, A.C.8    Sporn, M.B.9    Gribble, G.W.10
  • 47
    • 21144438719 scopus 로고    scopus 로고
    • Synthetic triterpenoids co-operate with tumor necrosis factor-related apoptosis-inducing ligand to induce apoptosis of breast cancer cells
    • COI: 1:CAS:528:DC%2BD2MXks1Ohurg%3D, PID: 15930300
    • Hyer ML, Croxton R, Krajewska M, Krajewski S, Kress CL, Lu M, Suh N, Sporn MB, Cryns VL, Zapata JM, Reed JC (2005) Synthetic triterpenoids co-operate with tumor necrosis factor-related apoptosis-inducing ligand to induce apoptosis of breast cancer cells. Cancer Res 65:4799–4808
    • (2005) Cancer Res , vol.65 , pp. 4799-4808
    • Hyer, M.L.1    Croxton, R.2    Krajewska, M.3    Krajewski, S.4    Kress, C.L.5    Lu, M.6    Suh, N.7    Sporn, M.B.8    Cryns, V.L.9    Zapata, J.M.10    Reed, J.C.11
  • 48
  • 49
    • 84876329009 scopus 로고    scopus 로고
    • Does night work increase the risk of breast cancer? A systematic review and meta-analysis of epidemiological studies
    • PID: 23403128
    • Jia Y, Lu Y, Wu K, Lin Q, Shen W, Zhu M, Huang S, Chen J (2013) Does night work increase the risk of breast cancer? A systematic review and meta-analysis of epidemiological studies. Cancer Epidemiol 37:197–206
    • (2013) Cancer Epidemiol , vol.37 , pp. 197-206
    • Jia, Y.1    Lu, Y.2    Wu, K.3    Lin, Q.4    Shen, W.5    Zhu, M.6    Huang, S.7    Chen, J.8
  • 50
    • 33845904405 scopus 로고    scopus 로고
    • Chemoprevention of breast cancer with selective oestrogen-receptor modulators
    • COI: 1:CAS:528:DC%2BD28XhtlCht7bM, PID: 17186017
    • Jordan VC (2007) Chemoprevention of breast cancer with selective oestrogen-receptor modulators. Nat Rev Cancer 7:46–53
    • (2007) Nat Rev Cancer , vol.7 , pp. 46-53
    • Jordan, V.C.1
  • 51
    • 84860128688 scopus 로고    scopus 로고
    • Dietary supplements and natural products in breast cancer trials
    • Kado K, Forsyth A, Patel PR, Schwartz JA (2012) Dietary supplements and natural products in breast cancer trials. Front Biosci 4:546–567
    • (2012) Front Biosci , vol.4 , pp. 546-567
    • Kado, K.1    Forsyth, A.2    Patel, P.R.3    Schwartz, J.A.4
  • 52
    • 84867027899 scopus 로고    scopus 로고
    • Synthesis, anti-proliferative and proapoptotic activity of novel oleanolic acid azaheterocyclic derivatives
    • COI: 1:CAS:528:DC%2BC38XhsVWns73F
    • Kang X, Hu J, Gao Z, Ju Y, Xu C (2012) Synthesis, anti-proliferative and proapoptotic activity of novel oleanolic acid azaheterocyclic derivatives. Med Chem Commun 3:1245–1249
    • (2012) Med Chem Commun , vol.3 , pp. 1245-1249
    • Kang, X.1    Hu, J.2    Gao, Z.3    Ju, Y.4    Xu, C.5
  • 53
    • 79959189104 scopus 로고    scopus 로고
    • Potential utility of natural products as regulators of breast cancer-associated aromatase promoters
    • COI: 1:CAS:528:DC%2BC3MXotVKktb4%3D, PID: 21693041
    • Khan SI, Zhao J, Khan IA, Walker LA, Dasmahapatra AK (2011) Potential utility of natural products as regulators of breast cancer-associated aromatase promoters. Reprod Biol Endocrinol 9:91
    • (2011) Reprod Biol Endocrinol , vol.9 , pp. 91
    • Khan, S.I.1    Zhao, J.2    Khan, I.A.3    Walker, L.A.4    Dasmahapatra, A.K.5
  • 54
    • 79955829428 scopus 로고    scopus 로고
    • CDDO-imidazolide induces DNA damage, G2/M arrest and apoptosis in BRCA1-mutated breast cancer cells
    • COI: 1:CAS:528:DC%2BC3MXktl2lur4%3D
    • Kim EH, Deng CX, Sporn MB, Liby KT (2011) CDDO-imidazolide induces DNA damage, G2/M arrest and apoptosis in BRCA1-mutated breast cancer cells. Cancer Prev Res 4:425–434
    • (2011) Cancer Prev Res , vol.4 , pp. 425-434
    • Kim, E.H.1    Deng, C.X.2    Sporn, M.B.3    Liby, K.T.4
  • 58
    • 80053088605 scopus 로고    scopus 로고
    • Inhibition of tumor progression by naturally occurring terpenoids
    • COI: 1:CAS:528:DC%2BC3MXht1WqtLbI, PID: 21936626
    • Kuttan G, Pratheeshkumar P, Manu KA, Kuttan R (2011) Inhibition of tumor progression by naturally occurring terpenoids. Pharm Biol 49:995–1007
    • (2011) Pharm Biol , vol.49 , pp. 995-1007
    • Kuttan, G.1    Pratheeshkumar, P.2    Manu, K.A.3    Kuttan, R.4
  • 59
    • 84860491625 scopus 로고    scopus 로고
    • Paviosides A–H, eight new oleane type saponins from Aesculus pavia with cytotoxic activity
    • COI: 1:CAS:528:DC%2BC38XlsFCrtLg%3D, PID: 22507208
    • Lanzotti V, Termolino P, Dolci M, Curir P (2012) Paviosides A–H, eight new oleane type saponins from Aesculus pavia with cytotoxic activity. Bioorg Med Chem 20:3280–3286
    • (2012) Bioorg Med Chem , vol.20 , pp. 3280-3286
    • Lanzotti, V.1    Termolino, P.2    Dolci, M.3    Curir, P.4
  • 60
    • 0141507973 scopus 로고    scopus 로고
    • Activation of peroxisome proliferators-activated receptor gamma by a novel synthetic triterpenoid 2-cyano-3,12-dioxoleana-1,9-dien-28oic acid induces growth arrest and apoptosis in breast cancer cells
    • COI: 1:CAS:528:DC%2BD3sXnvVSis7Y%3D, PID: 14522919
    • Lapillonne H, Konopleva M, Tsao T, Gold D, McQueen T, Sutherland RL, Madden T, Andreeff M (2003) Activation of peroxisome proliferators-activated receptor gamma by a novel synthetic triterpenoid 2-cyano-3,12-dioxoleana-1,9-dien-28oic acid induces growth arrest and apoptosis in breast cancer cells. Cancer Res 63:5926–5939
    • (2003) Cancer Res , vol.63 , pp. 5926-5939
    • Lapillonne, H.1    Konopleva, M.2    Tsao, T.3    Gold, D.4    McQueen, T.5    Sutherland, R.L.6    Madden, T.7    Andreeff, M.8
  • 61
    • 74049157757 scopus 로고    scopus 로고
    • Pentacyclic triterpenes of the lupane, oleanane and ursane group as tools in cancer therapy
    • COI: 1:CAS:528:DC%2BC3cXit1agsQ%3D%3D, PID: 19742422
    • Laszczyk MN (2009) Pentacyclic triterpenes of the lupane, oleanane and ursane group as tools in cancer therapy. Planta Med 75:1549–1560
    • (2009) Planta Med , vol.75 , pp. 1549-1560
    • Laszczyk, M.N.1
  • 62
    • 84867055462 scopus 로고    scopus 로고
    • Synthetic oleanane triterpenoids: multifunctional drugs with a broad range of applications for prevention and treatment of chronic disease
    • COI: 1:CAS:528:DC%2BC3sXhslaltQ%3D%3D, PID: 22966038
    • Liby KT, Sporn MB (2012) Synthetic oleanane triterpenoids: multifunctional drugs with a broad range of applications for prevention and treatment of chronic disease. Pharmacol Rev 64:972–1003
    • (2012) Pharmacol Rev , vol.64 , pp. 972-1003
    • Liby, K.T.1    Sporn, M.B.2
  • 63
    • 34247526984 scopus 로고    scopus 로고
    • Triterpenoids and rexinoids as multifunctional agents for the prevention and treatment of cancer
    • COI: 1:CAS:528:DC%2BD2sXksFSiu7g%3D, PID: 17446857
    • Liby KT, Yore MM, Sporn MB (2007) Triterpenoids and rexinoids as multifunctional agents for the prevention and treatment of cancer. Nat Rev Cancer 7:357–369
    • (2007) Nat Rev Cancer , vol.7 , pp. 357-369
    • Liby, K.T.1    Yore, M.M.2    Sporn, M.B.3
  • 64
    • 51649111044 scopus 로고    scopus 로고
    • Prevention and treatment of experimental estrogen receptor-negative mammary carcinogenesis by the synthetic triterpenoid CDDO-methyl ester and the rexinoid LG100268
    • COI: 1:CAS:528:DC%2BD1cXosFGitb8%3D, PID: 18628471
    • Liby K, Risingsong R, Royce DB, Williams CR, Yore MM, Honda T, Gribble GW, Lamph WW, Vannini N, Sogno I, Albini A, Sporn MB (2008) Prevention and treatment of experimental estrogen receptor-negative mammary carcinogenesis by the synthetic triterpenoid CDDO-methyl ester and the rexinoid LG100268. Clin Cancer Res 14:4556–4563
    • (2008) Clin Cancer Res , vol.14 , pp. 4556-4563
    • Liby, K.1    Risingsong, R.2    Royce, D.B.3    Williams, C.R.4    Yore, M.M.5    Honda, T.6    Gribble, G.W.7    Lamph, W.W.8    Vannini, N.9    Sogno, I.10    Albini, A.11    Sporn, M.B.12
  • 66
    • 34249337388 scopus 로고    scopus 로고
    • The novel triterpenoid C-28 methyl ester of 2-cyano-3,12-dioxolen-1,9-dien-28-oic acid inhibits metastatic murine breast tumor growth through inactivation of STAT3 signaling
    • COI: 1:CAS:528:DC%2BD2sXltVyrs70%3D, PID: 17483332
    • Ling X, Konopleva M, Zeng Z, Ruvolo V, Stephens LC, Schober W, McQueen T, Dietrich M, Madden TL, Andreeff M (2007) The novel triterpenoid C-28 methyl ester of 2-cyano-3,12-dioxolen-1,9-dien-28-oic acid inhibits metastatic murine breast tumor growth through inactivation of STAT3 signaling. Cancer Res 67:4210–4218
    • (2007) Cancer Res , vol.67 , pp. 4210-4218
    • Ling, X.1    Konopleva, M.2    Zeng, Z.3    Ruvolo, V.4    Stephens, L.C.5    Schober, W.6    McQueen, T.7    Dietrich, M.8    Madden, T.L.9    Andreeff, M.10
  • 67
    • 9744222928 scopus 로고    scopus 로고
    • Potential synergy of phytochemicals in cancer prevention: mechanism of action
    • COI: 1:CAS:528:DC%2BD2cXhtVOmtLjP, PID: 15570057
    • Liu RH (2004) Potential synergy of phytochemicals in cancer prevention: mechanism of action. J Nutr 134:3479S–3485S
    • (2004) J Nutr , vol.134 , pp. 3479S-3485S
    • Liu, R.H.1
  • 68
    • 23044440041 scopus 로고    scopus 로고
    • Oleanolic acid and ursolic acid: research perspectives
    • COI: 1:CAS:528:DC%2BD2MXmvVKnsbw%3D, PID: 15994040
    • Liu J (2005) Oleanolic acid and ursolic acid: research perspectives. J Ethnopharmacol 100:92–94
    • (2005) J Ethnopharmacol , vol.100 , pp. 92-94
    • Liu, J.1
  • 69
    • 0034727787 scopus 로고    scopus 로고
    • Post-initiation treatment of rats with indole-3-carbinol or beta-naphthoflavone does not suppress 7,12-dimethylbenz[a]anthracene-induced mammary gland carcinogenesis
    • COI: 1:CAS:528:DC%2BD3cXoslWrsbk%3D, PID: 11053651
    • Malejka-Giganti D, Niehans GA, Reichert MA, Bliss RL (2000) Post-initiation treatment of rats with indole-3-carbinol or beta-naphthoflavone does not suppress 7,12-dimethylbenz[a]anthracene-induced mammary gland carcinogenesis. Cancer Lett 160:209–218
    • (2000) Cancer Lett , vol.160 , pp. 209-218
    • Malejka-Giganti, D.1    Niehans, G.A.2    Reichert, M.A.3    Bliss, R.L.4
  • 70
    • 84889062695 scopus 로고    scopus 로고
    • Simultaneous disruption of estrogen receptor and Wnt/β-catenin signaling is involved in methyl amooranin-mediated chemoprevention of mammary gland tumorigenesis in rats
    • COI: 1:CAS:528:DC%2BC3sXhsFeqtLfP, PID: 24078029
    • Mandal A, Bhatia D, Bishayee A (2013a) Simultaneous disruption of estrogen receptor and Wnt/β-catenin signaling is involved in methyl amooranin-mediated chemoprevention of mammary gland tumorigenesis in rats. Mol Cell Biochem 384:239–250
    • (2013) Mol Cell Biochem , vol.384 , pp. 239-250
    • Mandal, A.1    Bhatia, D.2    Bishayee, A.3
  • 71
    • 84911433519 scopus 로고    scopus 로고
    • Suppression of inflammatory cascade is implicated in methyl amooranin-mediated inhibition of experimental mammary carcinogenesis
    • Mol Carcinog (in press)
    • Mandal A, Bhatia D, Bishayee A (2013b) Suppression of inflammatory cascade is implicated in methyl amooranin-mediated inhibition of experimental mammary carcinogenesis. Mol Carcinog (in press)
    • Mol Carcinog (in press)
    • Mandal, A.1    Bhatia, D.2    Bishayee, A.3
  • 72
    • 19544384604 scopus 로고    scopus 로고
    • The influence of Calendulae officinalis flos extracts on cell cultures, and the chromatographic analysis of extracts
    • COI: 1:CAS:528:DC%2BD2MXltVegsbw%3D, PID: 15925220
    • Matysik G, Wójciak-Kosior M, Paduch R (2005) The influence of Calendulae officinalis flos extracts on cell cultures, and the chromatographic analysis of extracts. J Pharm Biomed Anal 38:285–292
    • (2005) J Pharm Biomed Anal , vol.38 , pp. 285-292
    • Matysik, G.1    Wójciak-Kosior, M.2    Paduch, R.3
  • 73
    • 80055082073 scopus 로고    scopus 로고
    • Triterpenoid constituents from the roots of Paeonia rockii ssp. rockii
    • COI: 1:CAS:528:DC%2BC3MXht1ClsLfP, PID: 21954959
    • Mencherini T, Picerno P, Festa M, Russo P, Capasso A, Aquino R (2011) Triterpenoid constituents from the roots of Paeonia rockii ssp. rockii. J Nat Prod 74:2116–2121
    • (2011) J Nat Prod , vol.74 , pp. 2116-2121
    • Mencherini, T.1    Picerno, P.2    Festa, M.3    Russo, P.4    Capasso, A.5    Aquino, R.6
  • 74
    • 79954575341 scopus 로고    scopus 로고
    • d-Limonene: a bioactive food component from citrus and evidence for a potential role in breast cancer prevention and treatment
    • Miller JA, Thompson PA, Hakim IA, Sherry Chow HH, Thompson CA (2011) d-Limonene: a bioactive food component from citrus and evidence for a potential role in breast cancer prevention and treatment. Oncol Rev 5:31–42
    • (2011) Oncol Rev , vol.5 , pp. 31-42
    • Miller, J.A.1    Thompson, P.A.2    Hakim, I.A.3    Sherry Chow, H.H.4    Thompson, C.A.5
  • 75
    • 8444253806 scopus 로고    scopus 로고
    • Pentacyclic triterpenoic acids: new chemoprotective compounds. Minireview
    • PID: 15640935
    • Ovesná Z, Vachálková A, Horváthová K, Tóthová D (2004) Pentacyclic triterpenoic acids: new chemoprotective compounds. Minireview. Neoplasma 51:327–333
    • (2004) Neoplasma , vol.51 , pp. 327-333
    • Ovesná, Z.1    Vachálková, A.2    Horváthová, K.3    Tóthová, D.4
  • 76
    • 84891830724 scopus 로고    scopus 로고
    • Alcohol consumption and breast cancer risk among women from five ethnic groups with light to moderate intakes: the multiethnic cohort study
    • Park SY, Kolonel LN, Lim U, White KK, Henderson BE, Wilkens LR (2013) Alcohol consumption and breast cancer risk among women from five ethnic groups with light to moderate intakes: the multiethnic cohort study. Int J Cancer 134:1504–1510
    • (2013) Int J Cancer , vol.134 , pp. 1504-1510
    • Park, S.Y.1    Kolonel, L.N.2    Lim, U.3    White, K.K.4    Henderson, B.E.5    Wilkens, L.R.6
  • 77
    • 84855856535 scopus 로고    scopus 로고
    • Triterpenoids for cancer prevention and treatment: current status and future prospects
    • COI: 1:CAS:528:DC%2BC38XitVehtbo%3D, PID: 21466427
    • Patlolla JM, Rao CV (2012) Triterpenoids for cancer prevention and treatment: current status and future prospects. Curr Pharm Biotechnol 13:147–155
    • (2012) Curr Pharm Biotechnol , vol.13 , pp. 147-155
    • Patlolla, J.M.1    Rao, C.V.2
  • 79
    • 79954582442 scopus 로고    scopus 로고
    • Effect of bardoxolone methyl on kidney function in patients with T2D and Stage 3b-4 CKD
    • COI: 1:CAS:528:DC%2BC3MXmtFyls7w%3D, PID: 21508635
    • Pergola PE, Krauth M, Huff JW, Ferguson DA, Ruiz S, Meyer CJ, Warnock DG (2011b) Effect of bardoxolone methyl on kidney function in patients with T2D and Stage 3b-4 CKD. Am J Nephrol 33:469–476
    • (2011) Am J Nephrol , vol.33 , pp. 469-476
    • Pergola, P.E.1    Krauth, M.2    Huff, J.W.3    Ferguson, D.A.4    Ruiz, S.5    Meyer, C.J.6    Warnock, D.G.7
  • 80
    • 73349109760 scopus 로고    scopus 로고
    • Triterpenoids as new promising anticancer drugs
    • COI: 1:CAS:528:DC%2BD1MXht1GitrvP, PID: 19745720
    • Petronelli A, Pannitteri G, Testa U (2009) Triterpenoids as new promising anticancer drugs. Anticancer Drugs 20:880–892
    • (2009) Anticancer Drugs , vol.20 , pp. 880-892
    • Petronelli, A.1    Pannitteri, G.2    Testa, U.3
  • 81
    • 84871783047 scopus 로고    scopus 로고
    • Obesity as a risk factor for triple-negative breast cancers: a systematic review and meta-analysis
    • PID: 23179600
    • Pierobon M, Frankenfeld CL (2013) Obesity as a risk factor for triple-negative breast cancers: a systematic review and meta-analysis. Breast Cancer Res Treat 137:307–314
    • (2013) Breast Cancer Res Treat , vol.137 , pp. 307-314
    • Pierobon, M.1    Frankenfeld, C.L.2
  • 83
    • 84859156298 scopus 로고    scopus 로고
    • Oleanolic acid
    • COI: 1:CAS:528:DC%2BC38XkvV2qu70%3D, PID: 22377690
    • Pollier J, Goossens A (2012) Oleanolic acid. Phytochemistry 77:10–15
    • (2012) Phytochemistry , vol.77 , pp. 10-15
    • Pollier, J.1    Goossens, A.2
  • 84
    • 81355135430 scopus 로고    scopus 로고
    • Combinatorial biosynthesis in plants: a (p)review on its potential and future exploitation
    • COI: 1:CAS:528:DC%2BC3MXhsVOjt7vO, PID: 21952724
    • Pollier J, Moses T, Goossens A (2011) Combinatorial biosynthesis in plants: a (p)review on its potential and future exploitation. Nat Prod Rep 28:1897–1916
    • (2011) Nat Prod Rep , vol.28 , pp. 1897-1916
    • Pollier, J.1    Moses, T.2    Goossens, A.3
  • 85
    • 0008761101 scopus 로고
    • Studies on cancer in Ayurveda and its management
    • Prasad GC (1987) Studies on cancer in Ayurveda and its management. J Res Ayurveda Siddha 8:147–167
    • (1987) J Res Ayurveda Siddha , vol.8 , pp. 147-167
    • Prasad, G.C.1
  • 86
    • 0008784744 scopus 로고    scopus 로고
    • Antitumor activity of amooranin from Amoora rohituka stem bark
    • COI: 1:CAS:528:DyaK28Xht1GgtL8%3D
    • Rabi T (1996) Antitumor activity of amooranin from Amoora rohituka stem bark. Curr Sci 70:80–81
    • (1996) Curr Sci , vol.70 , pp. 80-81
    • Rabi, T.1
  • 87
    • 44949129094 scopus 로고    scopus 로고
    • Novel synthetic triterpenoid methyl 25-hydroxy-3-oxoolean-12-en-28-oate induces apoptosis through JNK and p38 MAPK pathways in human breast adenocarcinoma MCF-7 cells
    • COI: 1:CAS:528:DC%2BD1cXntlWlur0%3D, PID: 18058803
    • Rabi T, Banerjee S (2008) Novel synthetic triterpenoid methyl 25-hydroxy-3-oxoolean-12-en-28-oate induces apoptosis through JNK and p38 MAPK pathways in human breast adenocarcinoma MCF-7 cells. Mol Carcinog 47:415–423
    • (2008) Mol Carcinog , vol.47 , pp. 415-423
    • Rabi, T.1    Banerjee, S.2
  • 88
    • 67349264062 scopus 로고    scopus 로고
    • Terpenoids and breast cancer chemoprevention
    • COI: 1:CAS:528:DC%2BD1MXmsVGjsrc%3D, PID: 18636327
    • Rabi T, Bishayee A (2009) Terpenoids and breast cancer chemoprevention. Breast Cancer Res Treat 115:223–239
    • (2009) Breast Cancer Res Treat , vol.115 , pp. 223-239
    • Rabi, T.1    Bishayee, A.2
  • 89
    • 42949176994 scopus 로고    scopus 로고
    • Dietary terpenoids and prostate cancer chemoprevention
    • COI: 1:CAS:528:DC%2BD1cXnsVKqtro%3D, PID: 18508447
    • Rabi T, Gupta S (2008) Dietary terpenoids and prostate cancer chemoprevention. Front Biosci 13:3457–3469
    • (2008) Front Biosci , vol.13 , pp. 3457-3469
    • Rabi, T.1    Gupta, S.2
  • 90
    • 0036215180 scopus 로고    scopus 로고
    • Cytotoxic activity of amooranin and its derivatives
    • COI: 1:CAS:528:DC%2BD38Xjt1Wrtrs%3D, PID: 11933149
    • Rabi T, Karunagaram D, Nair MK, Bhattathiri VN (2002) Cytotoxic activity of amooranin and its derivatives. Phytother Res 16:S84–S86
    • (2002) Phytother Res , vol.16 , pp. S84-S86
    • Rabi, T.1    Karunagaram, D.2    Nair, M.K.3    Bhattathiri, V.N.4
  • 91
    • 0041823453 scopus 로고    scopus 로고
    • Novel drug amooranin induces apoptosis through caspase activity in human breast carcinoma cell lines
    • COI: 1:CAS:528:DC%2BD3sXlslOnsb0%3D, PID: 14503804
    • Rabi T, Ramachandran C, Fonseca HB, Nair RP, Alamo A, Melnick SJ, Escalon E (2003) Novel drug amooranin induces apoptosis through caspase activity in human breast carcinoma cell lines. Breast Cancer Res Treat 80:321–330
    • (2003) Breast Cancer Res Treat , vol.80 , pp. 321-330
    • Rabi, T.1    Ramachandran, C.2    Fonseca, H.B.3    Nair, R.P.4    Alamo, A.5    Melnick, S.J.6    Escalon, E.7
  • 92
    • 34250900940 scopus 로고    scopus 로고
    • Novel triterpenoid 25-hydroxy-3-oxoolean-12-en-28-oic acid induces growth arrest and apoptosis in breast cancer cells
    • COI: 1:CAS:528:DC%2BD2sXisVymtQ%3D%3D, PID: 17028990
    • Rabi T, Wang L, Banerjee S (2007) Novel triterpenoid 25-hydroxy-3-oxoolean-12-en-28-oic acid induces growth arrest and apoptosis in breast cancer cells. Breast Cancer Res Treat 101:27–36
    • (2007) Breast Cancer Res Treat , vol.101 , pp. 27-36
    • Rabi, T.1    Wang, L.2    Banerjee, S.3
  • 93
    • 84902547196 scopus 로고    scopus 로고
    • AMR-Me inhibits PI3K/Akt signaling in hormone-dependent MCF-7 breast cancer cells and inactivates NF-κB in hormone-independent MDA-MB-231 cells
    • Rabi T, Huwiler A, Zangemeister-Wittke U (2013) AMR-Me inhibits PI3K/Akt signaling in hormone-dependent MCF-7 breast cancer cells and inactivates NF-κB in hormone-independent MDA-MB-231 cells. Mol Carcinog (in press)
    • (2013) Mol Carcinog (in press)
    • Rabi, T.1    Huwiler, A.2
  • 94
    • 84855317068 scopus 로고    scopus 로고
    • Modulation of angiogenesis by dietary phytoconstituents in the prevention and intervention of breast cancer
    • COI: 1:CAS:528:DC%2BC3MXhsFaru7rE, PID: 22125182
    • Reuben SC, Gopalan A, Petit DM, Bishayee A (2012) Modulation of angiogenesis by dietary phytoconstituents in the prevention and intervention of breast cancer. Mol Nutr Food Res 56:14–29
    • (2012) Mol Nutr Food Res , vol.56 , pp. 14-29
    • Reuben, S.C.1    Gopalan, A.2    Petit, D.M.3    Bishayee, A.4
  • 95
    • 84870201236 scopus 로고    scopus 로고
    • Unifying mechanisms of action of the anticancer activities of triterpenoids and synthetic analogs
    • COI: 1:CAS:528:DC%2BC3sXlvFSlsg%3D%3D, PID: 22583404
    • Safe SH, Prather PL, Brents LK, Chadalapaka G, Jutooru I (2012) Unifying mechanisms of action of the anticancer activities of triterpenoids and synthetic analogs. Anticancer Agents Med Chem 12:1211–1220
    • (2012) Anticancer Agents Med Chem , vol.12 , pp. 1211-1220
    • Safe, S.H.1    Prather, P.L.2    Brents, L.K.3    Chadalapaka, G.4    Jutooru, I.5
  • 96
    • 0642368436 scopus 로고    scopus 로고
    • Plant-derived triterpenoids as potential antineoplastic agents
    • COI: 1:CAS:528:DC%2BD3sXms1WgsLs%3D, PID: 12871157
    • Setzer WN, Setzer MC (2003) Plant-derived triterpenoids as potential antineoplastic agents. Mini Rev Med Chem 3:540–556
    • (2003) Mini Rev Med Chem , vol.3 , pp. 540-556
    • Setzer, W.N.1    Setzer, M.C.2
  • 97
    • 84855172051 scopus 로고    scopus 로고
    • Proliferation-inhibiting and apoptosis-inducing effects of ursolic acid and oleanolic acid on multi-drug resistance cancer cells in vitro
    • COI: 1:CAS:528:DC%2BC3MXhtVSlu7nK, PID: 21826595
    • Shan JZ, Xuan YY, Ruan SQ, Sun M (2011) Proliferation-inhibiting and apoptosis-inducing effects of ursolic acid and oleanolic acid on multi-drug resistance cancer cells in vitro. Chin J Integr Med 17:607–611
    • (2011) Chin J Integr Med , vol.17 , pp. 607-611
    • Shan, J.Z.1    Xuan, Y.Y.2    Ruan, S.Q.3    Sun, M.4
  • 98
    • 84862779635 scopus 로고    scopus 로고
    • Targeted inhibition of tumor proliferation, survival, and metastasis by pentacyclic triterpenoids: potential role in prevention and therapy of cancer
    • COI: 1:CAS:528:DC%2BC38Xkslaqs7g%3D, PID: 22406826
    • Shanmugam MK, Nguyen AH, Kumar AP, Tan BK, Sethi G (2012) Targeted inhibition of tumor proliferation, survival, and metastasis by pentacyclic triterpenoids: potential role in prevention and therapy of cancer. Cancer Lett 320:158–170
    • (2012) Cancer Lett , vol.320 , pp. 158-170
    • Shanmugam, M.K.1    Nguyen, A.H.2    Kumar, A.P.3    Tan, B.K.4    Sethi, G.5
  • 99
    • 84877594282 scopus 로고    scopus 로고
    • Ursolic acid in cancer prevention and treatment: molecular targets, pharmacokinetics and clinical studies
    • COI: 1:CAS:528:DC%2BC3sXmt1CntL8%3D, PID: 23499879
    • Shanmugam MK, Dai X, Kumar AP, Tan BK, Sethi G, Bishayee A (2013) Ursolic acid in cancer prevention and treatment: molecular targets, pharmacokinetics and clinical studies. Biochem Pharmacol 85:1579–1587
    • (2013) Biochem Pharmacol , vol.85 , pp. 1579-1587
    • Shanmugam, M.K.1    Dai, X.2    Kumar, A.P.3    Tan, B.K.4    Sethi, G.5    Bishayee, A.6
  • 101
    • 84879297257 scopus 로고    scopus 로고
    • Chemopreventive and chemotherapeutic potential of curcumin in breast cancer
    • COI: 1:CAS:528:DC%2BC3sXhslGju7g%3D, PID: 23140290
    • Sinha D, Biswas J, Sung B, Aggarwal BB, Bishayee A (2012) Chemopreventive and chemotherapeutic potential of curcumin in breast cancer. Curr Drug Targets 13:1799–1819
    • (2012) Curr Drug Targets , vol.13 , pp. 1799-1819
    • Sinha, D.1    Biswas, J.2    Sung, B.3    Aggarwal, B.B.4    Bishayee, A.5
  • 103
    • 0037359363 scopus 로고    scopus 로고
    • Cardiovascular, antihyperlipidemic and antioxidant effects of oleanolic and ursolic acids in experimental hypertension
    • COI: 1:CAS:528:DC%2BD3sXksFGkt7Y%3D, PID: 12725563
    • Somova LO, Nadar A, Rammanan P, Shode FO (2003) Cardiovascular, antihyperlipidemic and antioxidant effects of oleanolic and ursolic acids in experimental hypertension. Phytomedicine 10:115–121
    • (2003) Phytomedicine , vol.10 , pp. 115-121
    • Somova, L.O.1    Nadar, A.2    Rammanan, P.3    Shode, F.O.4
  • 104
    • 30344458801 scopus 로고    scopus 로고
    • Determination of oleanolic acid in human plasma and study of its pharmacokinetics in Chinese healthy male volunteers by HPLC tandem mass spectrometry
    • COI: 1:CAS:528:DC%2BD28XksFChsw%3D%3D, PID: 16126358
    • Song M, Hang TJ, Wang Y, Jiang L, Wu XL, Zhang Z, Shen J, Zhang Y (2006) Determination of oleanolic acid in human plasma and study of its pharmacokinetics in Chinese healthy male volunteers by HPLC tandem mass spectrometry. J Pharm Biomed Anal 40:190–196
    • (2006) J Pharm Biomed Anal , vol.40 , pp. 190-196
    • Song, M.1    Hang, T.J.2    Wang, Y.3    Jiang, L.4    Wu, X.L.5    Zhang, Z.6    Shen, J.7    Zhang, Y.8
  • 106
    • 79953242026 scopus 로고    scopus 로고
    • New synthetic triterpenoids: potent agents for prevention and treatment of tissue injury caused by inflammatory and oxidative stress
    • COI: 1:CAS:528:DC%2BC3MXhvVWisrg%3D, PID: 21309592
    • Sporn MB, Liby KT, Yore MM, Fu L, Lopchuk JM, Gribble GW (2011) New synthetic triterpenoids: potent agents for prevention and treatment of tissue injury caused by inflammatory and oxidative stress. J Nat Prod 74:537–545
    • (2011) J Nat Prod , vol.74 , pp. 537-545
    • Sporn, M.B.1    Liby, K.T.2    Yore, M.M.3    Fu, L.4    Lopchuk, J.M.5    Gribble, G.W.6
  • 108
    • 56449128037 scopus 로고    scopus 로고
    • Oleanolic acid and related derivatives as medicinally important compounds
    • COI: 1:CAS:528:DC%2BD1cXhtlOksLfN, PID: 18618318
    • Sultana N, Ata A (2008) Oleanolic acid and related derivatives as medicinally important compounds. J Enzyme Inhib Med Chem 23:739–756
    • (2008) J Enzyme Inhib Med Chem , vol.23 , pp. 739-756
    • Sultana, N.1    Ata, A.2
  • 109
    • 28644444774 scopus 로고    scopus 로고
    • Saponins in Calendula officinalis L.—structure, biosynthesis, transport and biological activity
    • COI: 1:CAS:528:DC%2BD28Xht1Wjsrs%3D
    • Szakiel A, Ruszkowski D, Janiszowska W (2005) Saponins in Calendula officinalis L.—structure, biosynthesis, transport and biological activity. Phytochem Rev 4:151–158
    • (2005) Phytochem Rev , vol.4 , pp. 151-158
    • Szakiel, A.1    Ruszkowski, D.2    Janiszowska, W.3
  • 111
    • 84861024238 scopus 로고    scopus 로고
    • Terpenoids as potential chemopreventive and therapeutic agents in liver cancer
    • PID: 21969877
    • Thoppil RJ, Bishayee A (2011) Terpenoids as potential chemopreventive and therapeutic agents in liver cancer. World J Hepatol 3:228–249
    • (2011) World J Hepatol , vol.3 , pp. 228-249
    • Thoppil, R.J.1    Bishayee, A.2
  • 112
    • 84866182600 scopus 로고    scopus 로고
    • The synthetic triterpenoid CDDO-methyl ester delays estrogen receptor-negative mammary carcinogenesis in polyoma middle T mice
    • COI: 1:CAS:528:DC%2BC38Xptl2iur0%3D
    • Tran K, Risingsong R, Royce D, Williams CR, Sporn MB, Liby K (2012) The synthetic triterpenoid CDDO-methyl ester delays estrogen receptor-negative mammary carcinogenesis in polyoma middle T mice. Cancer Prev Res 5:726–734
    • (2012) Cancer Prev Res , vol.5 , pp. 726-734
    • Tran, K.1    Risingsong, R.2    Royce, D.3    Williams, C.R.4    Sporn, M.B.5    Liby, K.6
  • 113
    • 84872151878 scopus 로고    scopus 로고
    • The combination of the histone deacetylase inhibitor vorinostat and synthetic triterpenoids reduces tumorigenesis in mouse models of cancer
    • COI: 1:CAS:528:DC%2BC3sXktFSltA%3D%3D, PID: 23042302
    • Tran K, Risingsong R, Royce DB, Williams CR, Sporn MB, Pioli PA, Gediya LK, Njar VC, Liby KT (2013) The combination of the histone deacetylase inhibitor vorinostat and synthetic triterpenoids reduces tumorigenesis in mouse models of cancer. Carcinogenesis 34:199–210
    • (2013) Carcinogenesis , vol.34 , pp. 199-210
    • Tran, K.1    Risingsong, R.2    Royce, D.B.3    Williams, C.R.4    Sporn, M.B.5    Pioli, P.A.6    Gediya, L.K.7    Njar, V.C.8    Liby, K.T.9
  • 115
    • 58149392842 scopus 로고    scopus 로고
    • Synergy research: vitamins and secondary plant components in the maintenance of the redox-homeostasis and in cell signaling
    • COI: 1:CAS:528:DC%2BD1MXjslars7k%3D, PID: 19118991
    • Ulrich-Merzenich G, Zeitler H, Vetter H, Kraft K (2009) Synergy research: vitamins and secondary plant components in the maintenance of the redox-homeostasis and in cell signaling. Phytomedicine 16:2–16
    • (2009) Phytomedicine , vol.16 , pp. 2-16
    • Ulrich-Merzenich, G.1    Zeitler, H.2    Vetter, H.3    Kraft, K.4
  • 117
    • 85068965367 scopus 로고    scopus 로고
    • Phytochemicals in diets for breast cancer prevention: the importance of resveratrol and ursolic acid
    • Venugopal R, Liu RH (2012) Phytochemicals in diets for breast cancer prevention: the importance of resveratrol and ursolic acid. Food Sci Hum Wellness 1:1–13
    • (2012) Food Sci Hum Wellness , vol.1 , pp. 1-13
    • Venugopal, R.1    Liu, R.H.2
  • 119
    • 33845736982 scopus 로고    scopus 로고
    • Biosynthesis and engineering of isoprenoid small molecules
    • COI: 1:CAS:528:DC%2BD28XhtlaqsLjE, PID: 17115212
    • Withers ST, Keasling JD (2007) Biosynthesis and engineering of isoprenoid small molecules. Appl Microbiol Biotechnol 73:980–990
    • (2007) Appl Microbiol Biotechnol , vol.73 , pp. 980-990
    • Withers, S.T.1    Keasling, J.D.2
  • 120
    • 79952084572 scopus 로고    scopus 로고
    • Targeting inflammatory pathways by triterpenoids for prevention and treatment of cancer
    • COI: 1:CAS:528:DC%2BC3cXhsVSht7vO, PID: 22069560
    • Yadav VR, Prasad S, Sung B, Kannappan R, Aggarwal BB (2010) Targeting inflammatory pathways by triterpenoids for prevention and treatment of cancer. Toxins 2:2428–2466
    • (2010) Toxins , vol.2 , pp. 2428-2466
    • Yadav, V.R.1    Prasad, S.2    Sung, B.3    Kannappan, R.4    Aggarwal, B.B.5
  • 121
    • 77953533803 scopus 로고    scopus 로고
    • Targeting apoptosis pathway with natural terpenoids: implications for treatment of breast and prostate cancer
    • COI: 1:CAS:528:DC%2BC3cXmsF2qt7Y%3D, PID: 20298150
    • Yang H, Dou QP (2010) Targeting apoptosis pathway with natural terpenoids: implications for treatment of breast and prostate cancer. Curr Drug Targets 11:733–744
    • (2010) Curr Drug Targets , vol.11 , pp. 733-744
    • Yang, H.1    Dou, Q.P.2
  • 122
    • 84893758276 scopus 로고    scopus 로고
    • Effect of green tea catechins on breast carcinogenesis: a systematic review of in vitro and in vivo experimental studies
    • Yiannakopoulou EC (2014) Effect of green tea catechins on breast carcinogenesis: a systematic review of in vitro and in vivo experimental studies. Eur J Cancer Prev 23:84–89
    • (2014) Eur J Cancer Prev , vol.23 , pp. 84-89
    • Yiannakopoulou, E.C.1
  • 123
    • 84864687685 scopus 로고    scopus 로고
    • Bioavailability, distribution, and antioxidative effects of selected triterpenes in mice
    • COI: 1:CAS:528:DC%2BC38XhtVGntrrI, PID: 22816768
    • Yin MC, Lin MC, Mong MC, Lin CY (2012) Bioavailability, distribution, and antioxidative effects of selected triterpenes in mice. J Agric Food Chem 60:7697–7701
    • (2012) J Agric Food Chem , vol.60 , pp. 7697-7701
    • Yin, M.C.1    Lin, M.C.2    Mong, M.C.3    Lin, C.Y.4
  • 124
    • 0033000335 scopus 로고    scopus 로고
    • Two bioactive pentacyclic triterpene esters from the root bark of Hibiscus syriacus
    • COI: 1:CAS:528:DyaK1MXitFehu7k%3D, PID: 10346965
    • Yun BS, Ryoo IJ, Lee IK, Park KH, Choung DH, Han KH, Yoo ID (1999) Two bioactive pentacyclic triterpene esters from the root bark of Hibiscus syriacus. J Nat Prod 62:764–766
    • (1999) J Nat Prod , vol.62 , pp. 764-766
    • Yun, B.S.1    Ryoo, I.J.2    Lee, I.K.3    Park, K.H.4    Choung, D.H.5    Han, K.H.6    Yoo, I.D.7
  • 125
    • 69549089743 scopus 로고    scopus 로고
    • Chemical and biological characterization of oleanane triterpenoids from soy
    • COI: 1:CAS:528:DC%2BD1MXhtVWmtr7F, PID: 19701138
    • Zhang W, Popovich DG (2009) Chemical and biological characterization of oleanane triterpenoids from soy. Molecules 14:2959–2975
    • (2009) Molecules , vol.14 , pp. 2959-2975
    • Zhang, W.1    Popovich, D.G.2
  • 126
    • 78649391538 scopus 로고    scopus 로고
    • Methods and options for the heterologous production of complex natural products
    • PID: 21060956
    • Zhang H, Boghigian BA, Armando J, Pfeifer BA (2011) Methods and options for the heterologous production of complex natural products. Nat Prod Rep 28:125–151
    • (2011) Nat Prod Rep , vol.28 , pp. 125-151
    • Zhang, H.1    Boghigian, B.A.2    Armando, J.3    Pfeifer, B.A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.