Paviosides A-H, eight new oleane type saponins from Aesculus pavia with cytotoxic activity

Bioorganic and Medicinal Chemistry

Volumn 20, Issue 10, 2012, Pages 3280-3286

  Lanzotti, Virginia ^a   Termolino, Pasquale ^a   Dolci, Marcello ^b   Curir, Paolo ^c  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^b UNIVERSITY OF TURIN   (Italy)

^c CRA FSO   (Italy)

Author keywords

Aesculus pavia; Cytotoxic activity; Murine fibrosarcoma; Murine monocyte macrophage; NMR spectroscopy; Paviosides; Triterpenoid saponins

Indexed keywords

3 O [BETA DEXTRO XYLOPYRANOSYL(1-2)][ BETA DEXTRO GALACTOPYRANOSYL(1-4)] BETA DEXTRO GLUCOPYRANOSIDURONIC ACID 21 ANGELOYL 22 ACETYLBARRINGTOGENOL C; 3 O [BETA DEXTRO XYLOPYRANOSYL(1-2)][ BETA DEXTRO GALACTOPYRANOSYL(1-4)] BETA DEXTRO GLUCOPYRANOSIDURONIC ACID 21 TIGLOYL 22 ACETYLBARRINGTOGENOL C; 3 O [BETA DEXTRO XYLOPYRANOSYL(1-2)][ BETA DEXTRO GLUCOPYRANOSYL(1-4)] BETA DEXTRO GLUCOPYRANOSIDURONIC ACID 21 ANGELOYL 22 ACETYLBARRINGTOGENOL C; 3 O [BETA DEXTRO XYLOPYRANOSYL(1-2)][ BETA DEXTRO GLUCOPYRANOSYL(1-4)] BETA DEXTRO GLUCOPYRANOSIDURONIC ACID 21 TIGLOYL 22 ACETYLBARRINGTOGENOL C; 3 O [BETA DEXTRO XYLOPYRANOSYL(1-2)][ BETA DEXTRO XYLOPYRANOSYL(1-4)] BETA DEXTRO GLUCOPYRANOSIDURONIC ACID 21 ANGELOYL 22 ACETYLBARRINGTOGENOL C; 3 O [BETA DEXTRO XYLOPYRANOSYL(1-2)][ BETA DEXTRO XYLOPYRANOSYL(1-4)] BETA DEXTRO GLUCOPYRANOSIDURONIC ACID 21 ANGELOYL 22 ACETYLPROTOAESCIGENIN; 3 O [BETA DEXTRO XYLOPYRANOSYL(1-2)][ BETA DEXTRO XYLOPYRANOSYL(1-4)] BETA DEXTRO GLUCOPYRANOSIDURONIC ACID 21 TIGLOYL 22 ACETYLBARRINGTOGENOL C; 3 O [BETA DEXTRO XYLOPYRANOSYL(1-2)][ BETA DEXTRO XYLOPYRANOSYL(1-4)] BETA DEXTRO GLUCOPYRANOSIDURONIC ACID 21 TIGLOYL 22 ACETYLPROTOAESCIGENIN; AESCULUS PAVIA EXTRACT; AGLYCONE; CYTOTOXIC AGENT; GALACTOSE; GLUCOSE; PLANT EXTRACT; SAPONIN DERIVATIVE; UNCLASSIFIED DRUG; XYLOSE;

AESCULUS; AESCULUS PAVIA; ANIMAL CELL; ARTICLE; DRUG CYTOTOXICITY; DRUG SCREENING; DRUG STRUCTURE; FIBROSARCOMA; MACROPHAGE; MONOCYTE; NONHUMAN; PHYTOCHEMISTRY; STRUCTURE ACTIVITY RELATION;

AESCULUS; ANIMALS; CARBOHYDRATE SEQUENCE; CELL LINE, TUMOR; CELL SURVIVAL; FIBROSARCOMA; MACROPHAGES; MAGNETIC RESONANCE SPECTROSCOPY; MICE; MOLECULAR SEQUENCE DATA; OLEANOLIC ACID; PLANT COMPONENTS, AERIAL; PLANT EXTRACTS; SAPONINS;

AESCULUS PAVIA; MURINAE;

EID: 84860491625     PISSN: 09680896     EISSN: 14643391     Source Type: Journal    
DOI: 10.1016/j.bmc.2012.03.048     Document Type: Article

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