A novel synthetic oleanane triterpenoid, 2-cyano-3,12-dioxoolean-1,9- dien-28-oic acid, with potent differentiating, antiproliferative, and anti- inflammatory activity

Cancer Research

Volumn 59, Issue 2, 1999, Pages 336-341

  Suh, Nanjoo ^a,b   Wang, Yongping ^a,b   Honda, Tadashi ^c   Gribble, Gordon W ^c   Dmitrovsky, Ethan ^a,b   Hickey, William F ^b   Maue, Robert A ^b   Place, Andrew E ^a,b   Porter, Donna M ^b   Spinella, Michael J ^a,b   Williams, Charlotte R ^a,b   Wu, Gengfei ^a,b   Dannenberg, Andrew J ^f,g   Flanders, Kathleen C ^d   Letterio, John J ^d   Mangelsdorf, David J ^e   Nathan, Carl F ^f   Nguyen, Lananh ^d   Porter, Weston W ^e   Ren, Renee F ^d   Roberts, Anita B ^d   Roche, Nanette S ^d   Subbaramaiah, Kotha ^f,g   Sporn, Michael B ^a,b,h   more..

^a NORRIS COTTON CANCER CENTER   (United States)

^b Department of Pharmacology ^*  (United States)

^c Dartmouth College   (United States)

^d NATIONAL CANCER INSTITUTE   (United States)

^e UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^f WEILL CORNELL MEDICAL COLLEGE   (United States)

^g STRANG CANCER PREVENTION CENTER   (United States)

^h DARTMOUTH MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 CYANO 3,12 DIOXOOLEAN 1,9 DIENE 28 OIC ACID; TRITERPENOID; UNCLASSIFIED DRUG;

ANTIINFLAMMATORY ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL; CANCER INHIBITION; CELL CULTURE; CELL DIFFERENTIATION; DRUG MECHANISM; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

3T3 CELLS; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTINEOPLASTIC AGENTS; CELL DIFFERENTIATION; CYCLOOXYGENASE 2; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; ISOENZYMES; MEMBRANE PROTEINS; MICE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; OLEANOLIC ACID; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; RATS;

EID: 0033555614     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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