Novel triterpenoid 25-hydroxy-3-oxoolean-12-en-28-oic acid induces growth arrest and apoptosis in breast cancer cells

Breast Cancer Research and Treatment

Volumn 101, Issue 1, 2007, Pages 27-36

  Rabi, Thangaiyan ^a   Wang, Liming ^a   Banerjee, Sipra ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

Author keywords

Amooranin; Apoptosis; Breast cancer; Caspase 3; p53 status

Indexed keywords

25 HYDROXY 3 OXOOLEAN 12 EN 28 OIC ACID; DNA FRAGMENT; POLY(ADENOSINE DIPHOSPHATE RIBOSE); TRITERPENE DERIVATIVE; UNCLASSIFIED DRUG; AMOORANIN; CASPASE 3; CASPASE 7; CASPASE 9; CYSTEINE PROTEINASE INHIBITOR; CYTOCHROME C; PROTEIN P53; SMALL INTERFERING RNA; TRITERPENE;

APHANAMIXIS POLYSTACHYA; APOPTOSIS; ARTICLE; BREAST CANCER; BREAST CARCINOMA; CANCER CELL CULTURE; CELL GROWTH; CELL STRAIN MCF 7; CONTROLLED STUDY; DRUG EFFICACY; DRUG INHIBITION; DRUG STRUCTURE; GROWTH INHIBITION; HUMAN; HUMAN CELL; IN VITRO STUDY; INDIA; MITOCHONDRION; PRIORITY JOURNAL; PROTEIN DEGRADATION; TREE; UPREGULATION; BREAST TUMOR; CELL CYCLE; CELL PROLIFERATION; CELL SURVIVAL; CHEMICAL STRUCTURE; CHEMISTRY; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; ENDOPLASMIC RETICULUM; FEMALE; FLOW CYTOMETRY; GENETICS; METABOLISM; PATHOLOGY; SIGNAL TRANSDUCTION; TIME; TUMOR CELL LINE; WESTERN BLOTTING;

APOPTOSIS; BLOTTING, WESTERN; BREAST NEOPLASMS; CASPASE 3; CASPASE 7; CASPASE 9; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; CYSTEINE PROTEINASE INHIBITORS; CYTOCHROMES C; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOPLASMIC RETICULUM; FEMALE; FLOW CYTOMETRY; HUMANS; MOLECULAR STRUCTURE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TIME FACTORS; TRITERPENES; TUMOR SUPPRESSOR PROTEIN P53;

EID: 34250900940     PISSN: 01676806     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10549-006-9275-z     Document Type: Article

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