Human aldo-keto reductases and the metabolic activation of polycyclic aromatic hydrocarbons

Chemical Research in Toxicology

Volumn 27, Issue 11, 2014, Pages 1901-1917

  Penning, Trevor M ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALDO KETO REDUCTASE; ALDO KETO REDUCTASE 1B ENZYME; ALDO KETO REDUCTASE 1C ENZYME; BENZO[A]PYRENE; CATECHOL DERIVATIVE; CIGARETTE SMOKE; CYTOCHROME P450 1A1; CYTOCHROME P450 1B1; DEOXYGUANOSINE DERIVATIVE; DNA DIRECTED DNA POLYMERASE ALPHA; DNA POLYMERASE; HYDROGEN PEROXIDE; OXIDOREDUCTASE; POLYCYCLIC AROMATIC HYDROCARBON; PROTEIN P53; QUINONE DERIVATIVE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SUPEROXIDE; UNCLASSIFIED DRUG; ALDEHYDE REDUCTASE; CARBONYL REDUCTASE; DNA ADDUCT; POLLUTANT;

AMES TEST; ANTIOXIDANT RESPONSIVE ELEMENT; CARCINOGENICITY; CATALYSIS; CELL LINE; DIASTEREOISOMER; DNA ADDUCT; DNA DAMAGE; DNA STRAND BREAKAGE; EXCISION REPAIR; GENE FREQUENCY; GENE OVEREXPRESSION; GENETIC VARIABILITY; HUMAN; HUMAN CELL; HYDROLYSIS; IMMUNOBLOTTING; LIMIT OF DETECTION; LIPID PEROXIDATION; LIQUID CHROMATOGRAPHY; LUNG ALVEOLUS CELL; LUNG CANCER CELL LINE; METABOLIC ACTIVATION; MICHAEL ADDITION; MISSENSE MUTATION; MUTAGENICITY; NON SMALL CELL LUNG CANCER; NONHUMAN; NONSENSE MUTATION; OXIDATION; OXIDATION REDUCTION REACTION; POINT MUTATION; REVIEW; SINGLE NUCLEOTIDE POLYMORPHISM; STABLE ISOTOPE DILUTION LIQUID CHROMATOGRAPHY; TANDEM MASS SPECTROMETRY; TRANSCRIPTOMICS; ANIMAL; BIOCATALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; LUNG TUMOR; METABOLISM; POLLUTANT; SIGNAL TRANSDUCTION; TOXICITY;

ALDEHYDE REDUCTASE; ANIMALS; BIOCATALYSIS; CELL LINE; DNA ADDUCTS; ENVIRONMENTAL POLLUTANTS; HUMANS; LUNG NEOPLASMS; MOLECULAR STRUCTURE; OXIDATION-REDUCTION; POLYCYCLIC HYDROCARBONS, AROMATIC; SIGNAL TRANSDUCTION;

EID: 84910624218     PISSN: 0893228X     EISSN: 15205010     Source Type: Journal    
DOI: 10.1021/tx500298n     Document Type: Review

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