Detoxication of benzo[a]pyrene-7,8-dione by sulfotransferases (SULTS) in human lung cells

Journal of Biological Chemistry

Volumn 287, Issue 35, 2012, Pages 29909-29920

  Zhang, Li ^a   Huang, Meng ^a   Blair, Ian A ^a   Penning, Trevor M ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALDO-KETO REDUCTASE; ANAEROBIC CONDITIONS; CATALYTIC EFFICIENCIES; DITHIOTHREITOL; EXPRESSION LEVELS; HUMAN LUNG CELLS; ISOFORMS; ISOMERIC PRODUCTS; KINETIC PROFILES; LUNG CELLS; METABOLIC ACTIVATION; REDOX-ACTIVE; REGIOISOMERS; REVERSED PHASE HPLC; SUBSTRATE INHIBITION; SUBSTRATE SPECIFICITY; SULFONATE GROUPS;

CELL CULTURE; ISOMERS; POLYCYCLIC AROMATIC HYDROCARBONS; RESPIRATORY SYSTEM; SULFONATION;

PHENOLS;

7 HYDROXY BENZO[A]PYRENE 8 O SULFATE; 8 HYDROXY BENZO[A]PYRENE 7 O SULFATE; ADENOSINE 3' PHOSPHATE 5' PHOSPHOSULFATE; BENZO[A]PYRENE 7,8 CATECHOL; BENZO[A]PYRENE 7,8 CATECHOL MONOSULFATE; BENZO[A]PYRENE 7,8 DIONE; BENZO[A]PYRENE DERIVATIVE; CATECHOL; DITHIOTHREITOL; RECOMBINANT ENZYME; RECOMBINANT SULFOTRANSFERASE 1A1; SULFOTRANSFERASE; SULFOTRANSFERASE 1A1; SULFOTRANSFERASE 1A3; SULFOTRANSFERASE 1E1; UNCLASSIFIED DRUG;

ARTICLE; CANCER SUSCEPTIBILITY; CATALYSIS; CELL PROTECTION; DETOXIFICATION; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME INHIBITION; ENZYME POLYMORPHISM; ENZYME SPECIFICITY; GENOTOXICITY; HUMAN; HUMAN CELL; LUNG ALVEOLUS CELL; LUNG CANCER; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SULFONATION;

ARYLSULFOTRANSFERASE; BENZOPYRENES; CELL LINE, TUMOR; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; ISOENZYMES; LUNG NEOPLASMS; NEOPLASM PROTEINS;

NICOTIANA TABACUM;

EID: 84865500021     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.386052     Document Type: Article

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