Interception of benzo[a]pyrene-7,8-dione by UDP glucuronosyltransferases (UGTs) in human lung cells

Chemical Research in Toxicology

Volumn 26, Issue 10, 2013, Pages 1570-1578

  Zhang, Li ^a   Huang, Meng ^a   Blair, Ian A ^a   Penning, Trevor M ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BENZO[A]PYRENE 7,8 CATECHOL; BENZO[A]PYRENE 7,8 DIONE; BENZO[A]PYRENE DERIVATIVE; CATECHOL; DITHIOTHREITOL; ELECTROPHILE; GLUCURONOSYLTRANSFERASE; GLUCURONOSYLTRANSFERASE 1A1; GLUCURONOSYLTRANSFERASE 1A3; GLUCURONOSYLTRANSFERASE 2B7; POLYCYCLIC AROMATIC HYDROCARBON; QUINONE DERIVATIVE; REACTIVE OXYGEN METABOLITE; RECOMBINANT ENZYME; UNCLASSIFIED DRUG; URIDINE DIPHOSPHATE GLUCURONIC ACID;

ANAEROBIC CAPACITY; ARTICLE; CONTROLLED STUDY; ENZYME KINETICS; ENZYME MECHANISM; GLUCURONIDATION; HUMAN; HUMAN CELL; ISOMER; LIQUID CHROMATOGRAPHY; LUNG ALVEOLUS CELL; MICHAELIS MENTEN KINETICS; NUCLEOTIDE SEQUENCE; OXIDATION REDUCTION REACTION; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; TANDEM MASS SPECTROMETRY;

NICOTIANA TABACUM;

BENZOPYRENES; CATECHOLS; CELL LINE, TUMOR; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DITHIOTHREITOL; GLUCURONIDES; GLUCURONOSYLTRANSFERASE; HUMANS; KINETICS; LUNG; MASS SPECTROMETRY; OXIDATION-REDUCTION; PROTEIN ISOFORMS; RECOMBINANT PROTEINS;

EID: 84886694640     PISSN: 0893228X     EISSN: 15205010     Source Type: Journal    
DOI: 10.1021/tx400268q     Document Type: Article

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