Formation of 8-oxo-7,8-dihydro-2′-deoxyguanosine (8-oxo-dGuo) by PAH o-quinones: Involvement of reactive oxygen species and copper(II)/copper(I) redox cycling

Chemical Research in Toxicology

Volumn 18, Issue 6, 2005, Pages 1026-1037

  Park, Jong Heum ^a   Gopishetty, Sridhar ^a   Szewczuk, Lawrence M ^a   Troxel, Andrea B ^a   Harvey, Ronald G ^b   Penning, Trevor M ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

7,12 DIMETHYLBENZ[A]ANTHRACENE; 8 HYDROXYDEOXYGUANOSINE; BATHOCUPROINE; BENZOIC ACID; CATALASE; CHELATING AGENT; COPPER; DNA; FORMIC ACID; HYDROGEN PEROXIDE; KETONE DERIVATIVE; MANNITOL; POLYCYCLIC AROMATIC HYDROCARBON; QUINONE DERIVATIVE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SODIUM AZIDE; TIRON; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; COMPLEX FORMATION; ELECTROCHEMISTRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROLYSIS; OXIDATION REDUCTION REACTION; SALMON;

ANIMALS; COPPER; DEOXYGUANOSINE; DNA ADDUCTS; DNA DAMAGE; MALE; OXIDATION-REDUCTION; POLYCYCLIC HYDROCARBONS, AROMATIC; QUINONES; REACTIVE OXYGEN SPECIES; SALMON;

EID: 21144438119     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx050001a     Document Type: Article

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