Expression and characterization of four recombinant human dihydrodiol dehydrogenase isoforms: Oxidation of trans-7,8-dihydroxy-7,8- dihydrobenzo[a]pyrene to the activated o-quinone metabolite benzo[a]pyrene- 7,8-dione

Biochemistry

Volumn 37, Issue 19, 1998, Pages 6781-6790

  Burczynski, Michael E ^a   Harvey, Ronald G ^b   Penning, Trevor M ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,4 BENZOQUINONE; 7,8 DIHYDRO 7,8 DIHYDROXYBENZO[A]PYRENE; BENZO[A]PYRENE 7,8 DIHYDRODIOL 9,10 OXIDE; DIHYDRODIOL DEHYDROGENASE; ISOENZYME;

ARTICLE; CARCINOGENICITY; CONFORMATIONAL TRANSITION; DRUG CONFORMATION; DRUG OXIDATION; ENZYME ACTIVITY; ENZYME CONFORMATION; ENZYME INDUCTION; ESCHERICHIA COLI; HUMAN; MICHAELIS CONSTANT; NONHUMAN; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL;

BENZOPYRENES; BIOTRANSFORMATION; CARCINOMA, HEPATOCELLULAR; CATALYSIS; DIHYDROXYDIHYDROBENZOPYRENES; DNA, COMPLEMENTARY; ESCHERICHIA COLI; GENETIC VECTORS; GLYCINE; HUMANS; ISOENZYMES; KINETICS; LIVER; OXIDATION-REDUCTION; OXIDOREDUCTASES; PHOSPHOLIPID ETHERS; RECOMBINANT PROTEINS; STEREOISOMERISM; TUMOR CELLS, CULTURED;

ESCHERICHIA COLI; FELIS CATUS;

EID: 0032510704     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi972725u     Document Type: Article

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