Regulation of benzo[a]pyrene-mediated dna-and glutathione-adduct formation by 2,3,7,8-tetrachlorodibenzo-p -dioxin in human lung cells

Chemical Research in Toxicology

Volumn 24, Issue 1, 2011, Pages 89-98

  Gelhaus, Stacy L ^a,b   Harvey, Ronald G ^c   Penning, Trevor M ^b   Blair, Ian A ^a,b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; 7,8 DIHYDRO 7,8 DIHYDROXYBENZO[A]PYRENE; ANTI 7,8 DIHYDROXY 9,10 EPOXY 7,8,9,10 TETRAHYDRO BENZO[A]PYRENE; ANTI TRANS BENZO[A]PYRENE 7,8 DIHYDROXY 9,10 EPOXY 7,8,9,10 TETRAHYDRO N2 2' DEOXYGUANOSINE; AROMATIC HYDROCARBON RECEPTOR; BENZO[A]PYRENE; CARCINOGEN; CYTOCHROME P450 1A1; CYTOCHROME P450 1B1; DEOXYGUANOSINE; DIOXIN; DNA; EPOXIDE HYDROLASE; GLUTATHIONE; MESSENGER RNA; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DETOXIFICATION; DNA DAMAGE; DOWN REGULATION; ENANTIOMER; GENE EXPRESSION; HUMAN; HUMAN CELL; LIVER CELL; LUNG ALVEOLUS CELL; METABOLISM; UPREGULATION;

BENZO(A)PYRENE; CELL LINE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYTOCHROME P-450 ENZYME SYSTEM; DEOXYGUANOSINE; DNA ADDUCTS; EPOXIDE HYDROLASES; GLUTATHIONE; HUMANS; LUNG; RECEPTORS, ARYL HYDROCARBON; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TETRACHLORODIBENZODIOXIN;

EID: 78651471875     PISSN: 0893228X     EISSN: 15205010     Source Type: Journal    
DOI: 10.1021/tx100297z     Document Type: Article

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