Lack of contribution of covalent benzo[a]pyrene-7,8-quinone-DNA adducts in benzo[a]pyrene-induced mouse lung tumorigenesis

Chemico-Biological Interactions

Volumn 186, Issue 2, 2010, Pages 157-165

  Nesnow, Stephen ^a   Nelson, Garret ^a   Padgett, William T ^a   George, Michael H ^a   Moore, Tanya ^a   King, Leon C ^a   Adams, Linda D ^a   Ross, Jeffrey A ^a  

^a U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

Author keywords

Benzo a pyrene; Benzo a pyrene 7,8 quinone; Diol epoxide; DNA adducts

Indexed keywords

7,8 DIHYDRO 7,8 DIHYDROXYBENZO[A]PYRENE; BENZO[A]PYRENE; BENZO[A]PYRENE 7,8 QUINONE; QUINONE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; COVALENT BOND; DNA ADDUCT; LIVER; LUNG CARCINOGENESIS; LUNG PARENCHYMA; LUNG TOXICITY; MALE; MOUSE; NONHUMAN; WEIGHT REDUCTION;

7,8-DIHYDRO-7,8-DIHYDROXYBENZO(A)PYRENE 9,10-OXIDE; ACETYLCYSTEINE; ANIMALS; BENZO(A)PYRENE; CARCINOGENS; DNA ADDUCTS; FREE RADICAL SCAVENGERS; HUMANS; LUNG NEOPLASMS; MALE; MICE; MICE, INBRED A; MODELS, BIOLOGICAL; PHOSPHORUS RADIOISOTOPES; POLYCYCLIC HYDROCARBONS, AROMATIC;

MUS; RODENTIA;

EID: 77953538596     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbi.2010.03.037     Document Type: Article

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