-
1
-
-
0024593072
-
Characterization of human microsomal cytochrome P-450 enzymes
-
F. P. Guengerich: Characterization of human microsomal cytochrome P-450 enzymes. Ann. Rev. Pharmacol. Toxicol. 29, 241-264 (1989).
-
(1989)
Ann. Rev. Pharmacol. Toxicol.
, vol.29
, pp. 241-264
-
-
Guengerich, F.P.1
-
2
-
-
0026290294
-
Human cytochrome P450: Evolution, catalytic activities and interindividual variations in expression
-
F. J. Gonzalez and H. V. Gelboin: Human cytochrome P450: evolution, catalytic activities and interindividual variations in expression. Prog. Clin. Biol. Res. 372, 11-20 (1991).
-
(1991)
Prog. Clin. Biol. Res.
, vol.372
, pp. 11-20
-
-
Gonzalez, F.J.1
Gelboin, H.V.2
-
3
-
-
0025992864
-
Oxidation of toxic and carcinogenic chemicals by human cytochrome P-450 enzymes
-
F. P. Guengerich and T. Shimada: Oxidation of toxic and carcinogenic chemicals by human cytochrome P-450 enzymes. Chem. Res. Toxicol. 4, 391-407 (1991).
-
(1991)
Chem. Res. Toxicol.
, vol.4
, pp. 391-407
-
-
Guengerich, F.P.1
Shimada, T.2
-
4
-
-
0028237729
-
Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: Studies with liver microsomes of 30 Japanese and 30 Caucasians
-
T. Shimada, H. Yamazaki, M. Mimura, Y. Inui, and F. P. Guengerich: Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians. J. Pharmacol. Exp. Ther. 270, 414-423 (1994).
-
(1994)
J. Pharmacol. Exp. Ther.
, vol.270
, pp. 414-423
-
-
Shimada, T.1
Yamazaki, H.2
Mimura, M.3
Inui, Y.4
Guengerich, F.P.5
-
5
-
-
0026082836
-
cDNA-expressed human cytochrome P450s: A new age of molecular toxicology and human risk assessment
-
F. J. Gonzalez, C. L. Crespi, and H. V. Gelboin: cDNA-expressed human cytochrome P450s: a new age of molecular toxicology and human risk assessment. Mutat. Res. 247, 113-127 (1991).
-
(1991)
Mutat. Res.
, vol.247
, pp. 113-127
-
-
Gonzalez, F.J.1
Crespi, C.L.2
Gelboin, H.V.3
-
6
-
-
0028270821
-
Cytochrome P450 in human fetal liver significance and fetal-specific expression
-
M. Kitada and T. Kamataki: Cytochrome P450 in human fetal liver significance and fetal-specific expression. Drug. Metab. Rev. 26, 305-323 (1994).
-
(1994)
Drug. Metab. Rev.
, vol.26
, pp. 305-323
-
-
Kitada, M.1
Kamataki, T.2
-
7
-
-
0025278978
-
Fetus-specific expression of a form of cytochrome P-450 in human livers
-
M. Komori, K. Nishio, M. Kitada, K. Shiramatsu, K. Muroya, M. Soma, K. Nagashima, and T. Kamataki: Fetus-specific expression of a form of cytochrome P-450 in human livers. Biochemistry 29, 4430-4433 (1990).
-
(1990)
Biochemistry
, vol.29
, pp. 4430-4433
-
-
Komori, M.1
Nishio, K.2
Kitada, M.3
Shiramatsu, K.4
Muroya, K.5
Soma, M.6
Nagashima, K.7
Kamataki, T.8
-
8
-
-
0022255668
-
Purification and properties of cytochrome P-450 from homogenates of human fetal livers
-
M. Kitada, T. Kamataki, K. Itahashi, T. Rikihisa, R. Kato, and Y. Kanakubo: Purification and properties of cytochrome P-450 from homogenates of human fetal livers. Arch. Biochem. Biophys. 241, 275-280 (1985).
-
(1985)
Arch. Biochem. Biophys.
, vol.241
, pp. 275-280
-
-
Kitada, M.1
Kamataki, T.2
Itahashi, K.3
Rikihisa, T.4
Kato, R.5
Kanakubo, Y.6
-
9
-
-
0025317427
-
1 and 2-amino-3-methylimidazo[4,5-f]-quinoline by human adult and fetal livers
-
1 and 2-amino-3-methylimidazo[4,5-f]-quinoline by human adult and fetal livers. Cancer Res. 50, 2641-2645 (1990).
-
(1990)
Cancer Res.
, vol.50
, pp. 2641-2645
-
-
Kitada, M.1
Taneda, M.2
Ohta, K.3
Nagashima, K.4
Itahashi, K.5
Kamataki, T.6
-
10
-
-
0026759778
-
Immunochemical characterization and toxicological significance of P-450HFLb purified from human fetal livers
-
M. Kitada, T. Kato, S. Ohmori, T. Kamataki, K. Itahashi, F. P. Guengerich, T. Rikihisa, and Y. Kanakubo: Immunochemical characterization and toxicological significance of P-450HFLb purified from human fetal livers. Biochim. Biophys. Acta 1117, 301-305 (1992).
-
(1992)
Biochim. Biophys. Acta
, vol.1117
, pp. 301-305
-
-
Kitada, M.1
Kato, T.2
Ohmori, S.3
Kamataki, T.4
Itahashi, K.5
Guengerich, F.P.6
Rikihisa, T.7
Kanakubo, Y.8
-
11
-
-
0025903396
-
Four forms of cytochrome P-450 in human fetal liver: Purification and their capacity to activate promutagens
-
M. Kitada, M. Taneda, K. Itahashi, and T. Kamataki: Four forms of cytochrome P-450 in human fetal liver: purification and their capacity to activate promutagens. Jpn. J. Cancer Res. 82, 426-432 (1991).
-
(1991)
Jpn. J. Cancer Res.
, vol.82
, pp. 426-432
-
-
Kitada, M.1
Taneda, M.2
Itahashi, K.3
Kamataki, T.4
-
12
-
-
0026216276
-
Cytochrome P-450-dependent metabolism of xenobiotics in human lung
-
C. W. Wheeler and T. M. Guenthner: Cytochrome P-450-dependent metabolism of xenobiotics in human lung. J. Biochem. Toxicol. 6, 163-169 (1991).
-
(1991)
J. Biochem. Toxicol.
, vol.6
, pp. 163-169
-
-
Wheeler, C.W.1
Guenthner, T.M.2
-
13
-
-
0001594033
-
Extrahepatic microsomal forms: Lung microsomal cytochrome P-450 isozymes
-
(J. B. Schenkman, H. Greim, eds.), Springer-Verlag, Berlin
-
E. Arinç: Extrahepatic microsomal forms: Lung microsomal cytochrome P-450 isozymes. In "Handbook of Experimental Pharmacology, Cytochrome P450" (J. B. Schenkman, H. Greim, eds.), vol. 105, pp. 373-386, Springer-Verlag, Berlin, 1993.
-
(1993)
Handbook of Experimental Pharmacology, Cytochrome P450
, vol.105
, pp. 373-386
-
-
Arinç, E.1
-
14
-
-
0027077438
-
Characterization of human lung microsomal cytochrome P-450 1A1 and its role in the oxidation of chemical carcinogens
-
T. Shimada, C. H. Yun, H. Yamazaki, J. C. Gautier, P. H. Beaune, and F. P. Guengerich: Characterization of human lung microsomal cytochrome P-450 1A1 and its role in the oxidation of chemical carcinogens. Mol. Pharmacol. 41, 856-864 (1992).
-
(1992)
Mol. Pharmacol.
, vol.41
, pp. 856-864
-
-
Shimada, T.1
Yun, C.H.2
Yamazaki, H.3
Gautier, J.C.4
Beaune, P.H.5
Guengerich, F.P.6
-
15
-
-
0023868471
-
Metabolic activation of environmental carcinogens and mutagens by human liver microsomes: Role of cytochrome P-450 homologous to a 3-methylcholanthrene-inducible isozyme in rat liver
-
T. Shimada and Y. Okuda: Metabolic activation of environmental carcinogens and mutagens by human liver microsomes: role of cytochrome P-450 homologous to a 3-methylcholanthrene-inducible isozyme in rat liver. Biochem. Pharmacol. 37, 459-465 (1988).
-
(1988)
Biochem. Pharmacol.
, vol.37
, pp. 459-465
-
-
Shimada, T.1
Okuda, Y.2
-
16
-
-
0027519429
-
Characterization of cytochrome P450 2B6 in human liver microsomes
-
M. Mimura, T. Baba, H. Yamazaki, S. Ohmori, Y. Inui, F. J. Gonzalez, F. P. Guengerich, and T. Shimada: Characterization of cytochrome P450 2B6 in human liver microsomes. Drug. Metab. Dispos. 21, 1048-1056 (1993)
-
(1993)
Drug. Metab. Dispos.
, vol.21
, pp. 1048-1056
-
-
Mimura, M.1
Baba, T.2
Yamazaki, H.3
Ohmori, S.4
Inui, Y.5
Gonzalez, F.J.6
Guengerich, F.P.7
Shimada, T.8
-
17
-
-
0027990736
-
Bufuralol hydroxylation by cytochrome P450 2D6 and 1A2 enzymes in human liver microsomes
-
H. Yamazaki, Z. Guo, M. Persmark, M. Mimura, K. Inoue, F. P. Guengerich, and T. Shimada: Bufuralol hydroxylation by cytochrome P450 2D6 and 1A2 enzymes in human liver microsomes. Mol. Pharmacol. 46, 568-577 (1994).
-
(1994)
Mol. Pharmacol.
, vol.46
, pp. 568-577
-
-
Yamazaki, H.1
Guo, Z.2
Persmark, M.3
Mimura, M.4
Inoue, K.5
Guengerich, F.P.6
Shimada, T.7
-
18
-
-
0002254766
-
Analysis and characterization of enzymes
-
(A. W. Hayes, ed.), 3rd ed., Raven Press, New York
-
F. P. Guengerich: Analysis and characterization of enzymes. In "Principles and Methods of Toxicology" (A. W. Hayes, ed.), 3rd ed., pp. 1259-1313. Raven Press, New York, 1994.
-
(1994)
Principles and Methods of Toxicology
, pp. 1259-1313
-
-
Guengerich, F.P.1
-
19
-
-
0020434524
-
Purification and characterization of rat liver microsomal cytochrome P-450: Electrophoretic, spectral, catalytic, and immunochemical properties and inducibility of eight isozymes isolated from rats treated with phenobarbital or β-naphthoflavone
-
F. P. Guengerich, G. A. Dannan, S. T. Wright, M. V. Martin, and L. S. Kaminsky: Purification and characterization of rat liver microsomal cytochrome P-450: electrophoretic, spectral, catalytic, and immunochemical properties and inducibility of eight isozymes isolated from rats treated with phenobarbital or β-naphthoflavone. Biochemistry 21, 6019-6030 (1982).
-
(1982)
Biochemistry
, vol.21
, pp. 6019-6030
-
-
Guengerich, F.P.1
Dannan, G.A.2
Wright, S.T.3
Martin, M.V.4
Kaminsky, L.S.5
-
20
-
-
0022263133
-
Purification and characterization of the human liver cytochromes P-450 involved in debrisoquine 4-hydroxylation and phenacetin O-deethylation, two prototypes for genetic polymorphism in oxidative drug metabolism
-
L. M. Distlerath, P. Reilly, M. V. Martin, G. G. Davis, G. R. Wilkinson, and F. P. Guengerich: Purification and characterization of the human liver cytochromes P-450 involved in debrisoquine 4-hydroxylation and phenacetin O-deethylation, two prototypes for genetic polymorphism in oxidative drug metabolism. J. Biol Chem. 260, 9057-9067 (1985).
-
(1985)
J. Biol Chem.
, vol.260
, pp. 9057-9067
-
-
Distlerath, L.M.1
Reilly, P.2
Martin, M.V.3
Davis, G.G.4
Wilkinson, G.R.5
Guengerich, F.P.6
-
21
-
-
0025841777
-
Purification and characterization of human liver microsomal cytochrome P-450 2A6
-
C. H. Yun, T. Shimada, and F. P. Guengerich: Purification and characterization of human liver microsomal cytochrome P-450 2A6. Mol. Pharmacol. 40, 679-685 (1991).
-
(1991)
Mol. Pharmacol.
, vol.40
, pp. 679-685
-
-
Yun, C.H.1
Shimada, T.2
Guengerich, F.P.3
-
22
-
-
0022574425
-
Human liver microsomal cytochrome P-450 mephenytoin 4-hydroxylase, a prototype of genetic polymorphism in oxidative drug metabolism. Purification and characterization of two similar forms involved in the reaction
-
T. Shimada, K. S. Misono, and F. P. Guengerich: Human liver microsomal cytochrome P-450 mephenytoin 4-hydroxylase, a prototype of genetic polymorphism in oxidative drug metabolism. Purification and characterization of two similar forms involved in the reaction. J. Biol. Chem. 261, 909-921 (1986).
-
(1986)
J. Biol. Chem.
, vol.261
, pp. 909-921
-
-
Shimada, T.1
Misono, K.S.2
Guengerich, F.P.3
-
23
-
-
0026035519
-
Role of human cytochrome P-450 IIE1 in the oxidation of many low molecular weight cancer suspects
-
F. P. Guengerich, D. H. Kim, and M. Iwasaki: Role of human cytochrome P-450 IIE1 in the oxidation of many low molecular weight cancer suspects. Chem. Res. Toxicol. 4, 168-179 (1991).
-
(1991)
Chem. Res. Toxicol.
, vol.4
, pp. 168-179
-
-
Guengerich, F.P.1
Kim, D.H.2
Iwasaki, M.3
-
24
-
-
0022998708
-
Characterization of rat and human liver microsomal cytochrome P-450 forms involved in nifedipine oxidation, a prototype for genetic polymorphism in oxidative drug metabolism
-
F. P. Guengerich, M. V. Martin, P. H. Beaune, P. Kremers, T. Wolff, and D. J. Waxman: Characterization of rat and human liver microsomal cytochrome P-450 forms involved in nifedipine oxidation, a prototype for genetic polymorphism in oxidative drug metabolism. J. Biol. Chem. 261, 5051-5060 (1986).
-
(1986)
J. Biol. Chem.
, vol.261
, pp. 5051-5060
-
-
Guengerich, F.P.1
Martin, M.V.2
Beaune, P.H.3
Kremers, P.4
Wolff, T.5
Waxman, D.J.6
-
25
-
-
0028071497
-
Expression of modified human cytochrome P450 1A1 in Escherichia coli: Effects of 5′ substitution, stabilization, purification, spectral characterization, and catalytic properties
-
Z. Guo, E. Gillam, S. Ohmori, R. H. Tukey, and F. P. Guengerich: Expression of modified human cytochrome P450 1A1 in Escherichia coli: effects of 5′ substitution, stabilization, purification, spectral characterization, and catalytic properties. Arch. Biochem. Biophys. 312, 436-446 (1994).
-
(1994)
Arch. Biochem. Biophys.
, vol.312
, pp. 436-446
-
-
Guo, Z.1
Gillam, E.2
Ohmori, S.3
Tukey, R.H.4
Guengerich, F.P.5
-
26
-
-
0028358220
-
Expression of modified human cytochrome P450 1A2 in Escherichia coli. Stabilization, purification, spectral characterization, and catalytic activities of the enzymes
-
P. Sandhu, Z. Guo, T. Baba, M. V. Martin, R. H. Tukey, and F. P. Guengerich: Expression of modified human cytochrome P450 1A2 in Escherichia coli. Stabilization, purification, spectral characterization, and catalytic activities of the enzymes. Arch. Biochem. Biophys. 309, 168-177 (1994).
-
(1994)
Arch. Biochem. Biophys.
, vol.309
, pp. 168-177
-
-
Sandhu, P.1
Guo, Z.2
Baba, T.3
Martin, M.V.4
Tukey, R.H.5
Guengerich, F.P.6
-
27
-
-
0019741894
-
Production and application of antibodies to rat liver cytochrome P-450
-
L. S. Kaminsky, M. J. Fasco, and F. P. Guengerich: Production and application of antibodies to rat liver cytochrome P-450. Methods Enzymol. 74, 262-272 (1981).
-
(1981)
Methods Enzymol.
, vol.74
, pp. 262-272
-
-
Kaminsky, L.S.1
Fasco, M.J.2
Guengerich, F.P.3
-
28
-
-
0001477412
-
SOS function tests for studies of chemical carcinogenesis using Salmonella typhimurium TA1535/pSK1002, NM2009, and NM3009
-
T. Shimada, Y. Oda, H. Yamazaki, M. Mimura, and F. P. Guengerich: SOS function tests for studies of chemical carcinogenesis using Salmonella typhimurium TA1535/pSK1002, NM2009, and NM3009. Methods Mol. Genetics. 5, 342-355 (1994).
-
(1994)
Methods Mol. Genetics.
, vol.5
, pp. 342-355
-
-
Shimada, T.1
Oda, Y.2
Yamazaki, H.3
Mimura, M.4
Guengerich, F.P.5
-
29
-
-
0024365294
-
Human liver microsomal cytochrome P-450 enzymes involved in the bioactivation of procarcinogens detected by umu gene response in Salmonella typhimurium TA1535/pSK1002
-
T. Shimada, M. Iwasaki, M. V. Martin, and F. P. Guengerich: Human liver microsomal cytochrome P-450 enzymes involved in the bioactivation of procarcinogens detected by umu gene response in Salmonella typhimurium TA1535/pSK1002. Cancer Res. 49, 3218-3228 (1989).
-
(1989)
Cancer Res.
, vol.49
, pp. 3218-3228
-
-
Shimada, T.1
Iwasaki, M.2
Martin, M.V.3
Guengerich, F.P.4
-
30
-
-
0026712358
-
Use of a newly developed tester strain Salmonella Typhimurium. NM2009 for the study of metabolic activation of carcinogenic aromatic amines by rat liver microsomal cytochrome P-450 enzymes
-
H. Yamazaki, Y. Oda, and T. Shimada: Use of a newly developed tester strain Salmonella Typhimurium. NM2009 for the study of metabolic activation of carcinogenic aromatic amines by rat liver microsomal cytochrome P-450 enzymes. Mutat. Res. 272, 183-192 (1992).
-
(1992)
Mutat. Res.
, vol.272
, pp. 183-192
-
-
Yamazaki, H.1
Oda, Y.2
Shimada, T.3
-
31
-
-
0023276802
-
Cytochrome P-450-mediated activation of procarcinogens and promutagens to DNA-damaging products by measuring expression of umu gene in Salmonella typhimurium TA1535/ pSK1002
-
T. Shimada and S. Nakamura: Cytochrome P-450-mediated activation of procarcinogens and promutagens to DNA-damaging products by measuring expression of umu gene in Salmonella typhimurium TA1535/ pSK1002. Biochem. Pharmacol. 36, 1979-1987 (1987).
-
(1987)
Biochem. Pharmacol.
, vol.36
, pp. 1979-1987
-
-
Shimada, T.1
Nakamura, S.2
-
33
-
-
0027203704
-
Roles of different forms of cytochrome P450 in the activation of the promutagen 6-aminochrysene to genotoxic metabolites in human liver microsomes
-
H. Yamazaki, M. Mimura, Y. Oda, Y. Inui, T. Shiraga, K. Iwasaki, F. P. Guengerich, and T. Shimada: Roles of different forms of cytochrome P450 in the activation of the promutagen 6-aminochrysene to genotoxic metabolites in human liver microsomes. Carcinogenesis 14, 1271-1278 (1993).
-
(1993)
Carcinogenesis
, vol.14
, pp. 1271-1278
-
-
Yamazaki, H.1
Mimura, M.2
Oda, Y.3
Inui, Y.4
Shiraga, T.5
Iwasaki, K.6
Guengerich, F.P.7
Shimada, T.8
-
34
-
-
78651165715
-
The carbon monoxide-binding pigment of liver microsomes. I. Evidence for its hemoprotein nature
-
T. Omura and R. Sato: The carbon monoxide-binding pigment of liver microsomes. I. Evidence for its hemoprotein nature. J. Biol. Chem. 239, 2370-2378 (1964).
-
(1964)
J. Biol. Chem.
, vol.239
, pp. 2370-2378
-
-
Omura, T.1
Sato, R.2
-
35
-
-
0020028678
-
Estimation of isozymes of microsomal cytochrome P-450 in rats, rabbits, and humans using immu-nochemical staining coupled with sodium dodecyl sulfate-polyacrylamide gel electrophoresis
-
F. P. Guengerich, P. Wang, and N. K. Davidson: Estimation of isozymes of microsomal cytochrome P-450 in rats, rabbits, and humans using immu-nochemical staining coupled with sodium dodecyl sulfate-polyacrylamide gel electrophoresis. Biochemistry 21, 1698-1706 (1982).
-
(1982)
Biochemistry
, vol.21
, pp. 1698-1706
-
-
Guengerich, F.P.1
Wang, P.2
Davidson, N.K.3
-
36
-
-
71849104860
-
Protein measurement with the Folin phenol reagent
-
O. H. Lowry, N. J. Rosebrough, A. L. Farr, and R. L. Randall: Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193, 265-275 (1951).
-
(1951)
J. Biol. Chem.
, vol.193
, pp. 265-275
-
-
Lowry, O.H.1
Rosebrough, N.J.2
Farr, A.L.3
Randall, R.L.4
-
37
-
-
0025646757
-
Catalytic activities of human liver cytochrome P-450IIIA4 expressed in Saccharomyces cerevisiae
-
W. R. Brian, M. A. Sari, M. Iwasaki, T. Shimada, L. S. Kaminsky, and F. P. Guengerich: Catalytic activities of human liver cytochrome P-450IIIA4 expressed in Saccharomyces cerevisiae. Biochemistry 29, 11280-11292 (1990).
-
(1990)
Biochemistry
, vol.29
, pp. 11280-11292
-
-
Brian, W.R.1
Sari, M.A.2
Iwasaki, M.3
Shimada, T.4
Kaminsky, L.S.5
Guengerich, F.P.6
-
38
-
-
0028075688
-
Catalytic roles of rat and human cytochrome P450 2A enzymes in testosterone 7α-and coumarin 7-hydroxylations
-
H. Yamazaki, M. Mimura, C. Sugahara, and T. Shimada: Catalytic roles of rat and human cytochrome P450 2A enzymes in testosterone 7α-and coumarin 7-hydroxylations. Biochem. Pharmacol. 48, 1524-1527 (1994).
-
(1994)
Biochem. Pharmacol.
, vol.48
, pp. 1524-1527
-
-
Yamazaki, H.1
Mimura, M.2
Sugahara, C.3
Shimada, T.4
-
39
-
-
0028030038
-
Activation of procarcinogens by human cytochrome P450 enzymes expressed in Escherichia coli. Simplified bacterial systems for genotoxicity assays
-
T. Shimada, E. M. J. Gillam, P. Sandhu, R. H. Tukey, and F. P. Guengerich: Activation of procarcinogens by human cytochrome P450 enzymes expressed in Escherichia coli. Simplified bacterial systems for genotoxicity assays. Carcinogenesis 15, 2523-2529 (1994).
-
(1994)
Carcinogenesis
, vol.15
, pp. 2523-2529
-
-
Shimada, T.1
Gillam, E.M.J.2
Sandhu, P.3
Tukey, R.H.4
Guengerich, F.P.5
-
40
-
-
0018385578
-
Partial purification and properties of cytochrome P450 from homogenates of human fetal livers
-
M. Kitada and T. Kamataki: Partial purification and properties of cytochrome P450 from homogenates of human fetal livers. Biochem. Pharmacol. 28, 793-797 (1979).
-
(1979)
Biochem. Pharmacol.
, vol.28
, pp. 793-797
-
-
Kitada, M.1
Kamataki, T.2
-
41
-
-
0019139741
-
Differential induction by 2,3,7,8-tetrachlorodibenzo-p-dioxin of multiple forms of rabbit microsomal cytochrome P-450: Evidence for tissue specificity
-
H. H. Liem, U. Muller-Eberhard, and E. F. Johnson: Differential induction by 2,3,7,8-tetrachlorodibenzo-p-dioxin of multiple forms of rabbit microsomal cytochrome P-450: evidence for tissue specificity. Mol. Pharmacol. 18, 565-570 (1980).
-
(1980)
Mol. Pharmacol.
, vol.18
, pp. 565-570
-
-
Liem, H.H.1
Muller-Eberhard, U.2
Johnson, E.F.3
-
42
-
-
0023200455
-
P-450 HFLa, a form of cytochrome P-450 purified from human fetal livers, is the 16α-hydroxylase of dehydroepiandrosterone 3-sulfate
-
M. Kitada, T. Kamataki, K. Itahashi, T. Rikihisa, and Y. Kanakubo: P-450 HFLa, a form of cytochrome P-450 purified from human fetal livers, is the 16α-hydroxylase of dehydroepiandrosterone 3-sulfate. J. Biol. Chem. 262, 13534-13537 (1987).
-
(1987)
J. Biol. Chem.
, vol.262
, pp. 13534-13537
-
-
Kitada, M.1
Kamataki, T.2
Itahashi, K.3
Rikihisa, T.4
Kanakubo, Y.5
-
43
-
-
0024429907
-
1 by P-450 HFLa in human fetal livers
-
1 by P-450 HFLa in human fetal livers. Mutat. Res. 227, 53-58 (1989).
-
(1989)
Mutat. Res.
, vol.227
, pp. 53-58
-
-
Kitada, M.1
Taneda, M.2
Ohi, H.3
Komori, M.4
Itahashi, K.5
Nagao, M.6
Kamataki, T.7
-
44
-
-
0027180023
-
Identification of the fetal liver cytochrome CYP3A7 in human endometrium and placenta
-
J. D. Schuetz, S. Kauma, and P. S. Guzelian: Identification of the fetal liver cytochrome CYP3A7 in human endometrium and placenta. J. Clin. Invest. 92, 1018-1024 (1993).
-
(1993)
J. Clin. Invest.
, vol.92
, pp. 1018-1024
-
-
Schuetz, J.D.1
Kauma, S.2
Guzelian, P.S.3
-
45
-
-
0023118517
-
Significance of cytochrome P-450 (P-450 HFLa) of human fetal livers in the steroid and drug oxidations
-
M. Kitada, T. Kamataki, K. Itahashi, T. Rikihisa, and Y. Kanakubo: Significance of cytochrome P-450 (P-450 HFLa) of human fetal livers in the steroid and drug oxidations. Biochem. Pharmacol. 36, 453-456 (1987).
-
(1987)
Biochem. Pharmacol.
, vol.36
, pp. 453-456
-
-
Kitada, M.1
Kamataki, T.2
Itahashi, K.3
Rikihisa, T.4
Kanakubo, Y.5
-
46
-
-
0026547829
-
A new form of cytochrome P-450 responsible for mutagenic activation of 2-amino-3-methylimidazo[4,5-f]quinoline in human livers
-
K. Ubukata, H. Ohi, M. Kitada, and T. Kamataki: A new form of cytochrome P-450 responsible for mutagenic activation of 2-amino-3-methylimidazo[4,5-f]quinoline in human livers. Cancer Res. 52, 758-763 (1992).
-
(1992)
Cancer Res.
, vol.52
, pp. 758-763
-
-
Ubukata, K.1
Ohi, H.2
Kitada, M.3
Kamataki, T.4
-
47
-
-
0024326433
-
Roles of individual human cytochrome P-450 enzymes in the bioactivation of benzo(a)pyrene, 7,8-dihydroxy-7,8-dihydrobenzo(a)pyrene, and other dihydrodiol derivatives of polycyclic aromatic hydrocarbons
-
T. Shimada, M. V. Martin, D. Pruess-Schwartz, L. J. Marnett, and F. P. Guengerich: Roles of individual human cytochrome P-450 enzymes in the bioactivation of benzo(a)pyrene, 7,8-dihydroxy-7,8-dihydrobenzo(a)pyrene, and other dihydrodiol derivatives of polycyclic aromatic hydrocarbons. Cancer Res. 49, 6304-6312 (1989).
-
(1989)
Cancer Res.
, vol.49
, pp. 6304-6312
-
-
Shimada, T.1
Martin, M.V.2
Pruess-Schwartz, D.3
Marnett, L.J.4
Guengerich, F.P.5
-
48
-
-
0028797624
-
Oxidation of benzo[a]pyrene by recombinant human cytochrome P450 enzymes
-
E. Bauer, Z. Guo, Y. -F. Ueng, L. C. Bell, D. Zeldin, and F. P. Guengerich: Oxidation of benzo[a]pyrene by recombinant human cytochrome P450 enzymes. Chem. Res. Toxicol. 8, 136-142 (1995).
-
(1995)
Chem. Res. Toxicol.
, vol.8
, pp. 136-142
-
-
Bauer, E.1
Guo, Z.2
Ueng, Y.F.3
Bell, L.C.4
Zeldin, D.5
Guengerich, F.P.6
-
49
-
-
0026066337
-
Human embryonic cytochrome P450s: Phenoxazone ethers as probes for expression of functional isoforms during organogenesis
-
Q. P. Lee, A. G. Fantel, and M. R. Juchau: Human embryonic cytochrome P450s: phenoxazone ethers as probes for expression of functional isoforms during organogenesis. Biochem. Pharmacol. 42, 2377-2385 (1991).
-
(1991)
Biochem. Pharmacol.
, vol.42
, pp. 2377-2385
-
-
Lee, Q.P.1
Fantel, A.G.2
Juchau, M.R.3
-
50
-
-
0028223294
-
Cytochrome P-450-dependent biotransformation of 2-acetylaminofluorene in cell-free preparations of human embryonic hepatic, adrenal, pulmonary, and cardiac tissues
-
M. J. Namkung, H-Y. L. Yang, and M. R. Juchau: Cytochrome P-450-dependent biotransformation of 2-acetylaminofluorene in cell-free preparations of human embryonic hepatic, adrenal, pulmonary, and cardiac tissues. Drug. Metab. Dispos. 22, 331-337 (1994).
-
(1994)
Drug. Metab. Dispos.
, vol.22
, pp. 331-337
-
-
Namkung, M.J.1
Yang, H.-Y.L.2
Juchau, M.R.3
-
51
-
-
0028916165
-
Expression of functional cytochrome P4501Al in human embryonic hepatic tissues during organogenesis
-
H-Y. L. Yang, M. J. Namkung, and M. R. Juchau: Expression of functional cytochrome P4501Al in human embryonic hepatic tissues during organogenesis, Biochem. Pharmacol. 49, 717-726 (1995).
-
(1995)
Biochem. Pharmacol.
, vol.49
, pp. 717-726
-
-
Yang, H.-Y.L.1
Namkung, M.J.2
Juchau, M.R.3
-
52
-
-
0025277085
-
Induction and developmental expression of cytochrome P450IA1 messenger RNA in rat and human tissues: Detection by the polymerase chain reaction
-
C. J. Omiecinski, C. A. Redlich, and P. Costa: Induction and developmental expression of cytochrome P450IA1 messenger RNA in rat and human tissues: detection by the polymerase chain reaction. Cancer Res. 50, 4315-4321 (1990).
-
(1990)
Cancer Res.
, vol.50
, pp. 4315-4321
-
-
Omiecinski, C.J.1
Redlich, C.A.2
Costa, P.3
-
53
-
-
0026583913
-
Cytochrome P450IA expression in adult and fetal human liver
-
G. I. Murray, C. O. Foster, T. S. Barnes, R. J. Weaver, C. P. Snyder, S. Ewen, W. T. Melvin, and M. D. Burke: Cytochrome P450IA expression in adult and fetal human liver. Carcinogenesis 13, 165-169 (1992).
-
(1992)
Carcinogenesis
, vol.13
, pp. 165-169
-
-
Murray, G.I.1
Foster, C.O.2
Barnes, T.S.3
Weaver, R.J.4
Snyder, C.P.5
Ewen, S.6
Melvin, W.T.7
Burke, M.D.8
-
54
-
-
0027932864
-
Expression of xenobiotic-metabo-lizing cytochrome P450 forms in human adult and fetal liver
-
J. Hakkola, M. Pasanen, R. Purkunen, S. Saarikoski, O. Pelkonea, J. Maenpaa, A. Rane, and H. Raunio: Expression of xenobiotic-metabo-lizing cytochrome P450 forms in human adult and fetal liver. Biochem. Pharmacol. 48, 59-64 (1994).
-
(1994)
Biochem. Pharmacol.
, vol.48
, pp. 59-64
-
-
Hakkola, J.1
Pasanen, M.2
Purkunen, R.3
Saarikoski, S.4
Pelkonea, O.5
Maenpaa, J.6
Rane, A.7
Raunio, H.8
-
55
-
-
0028276386
-
Complete cDNA sequence of a human dioxin-inducible mRNA identifies a new gene subfamily of cytochrome P450 that maps to chromosome 2
-
T. R. Sutter, Y. M. Tang, C. L. Hayes, P. Wo Y-Y, W. Jabs, X. Li, H. Yia, C. W. Cody, and W. F. Greenlee: Complete cDNA sequence of a human dioxin-inducible mRNA identifies a new gene subfamily of cytochrome P450 that maps to chromosome 2. J. Biol. Chem. 269, 13092-13099 (1994).
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 13092-13099
-
-
Sutter, T.R.1
Tang, Y.M.2
Hayes, C.L.3
Wo, Y.-Y.P.4
Jabs, W.5
Li, X.6
Yia, H.7
Cody, C.W.8
Greenlee, W.F.9
-
56
-
-
0026485625
-
Polycyclic aromatic hydrocarbon metabolism in rat adrenal, ovary, and testis microsomes is catalyzed by the same novel cytochrome P450 (P450RAP)
-
S. Otto, K. K. Bhattacharyya, and C. R. Jefcoate: Polycyclic aromatic hydrocarbon metabolism in rat adrenal, ovary, and testis microsomes is catalyzed by the same novel cytochrome P450 (P450RAP). Endocrinology 131, 3067-3076 (1992).
-
(1992)
Endocrinology
, vol.131
, pp. 3067-3076
-
-
Otto, S.1
Bhattacharyya, K.K.2
Jefcoate, C.R.3
-
57
-
-
0026018303
-
A novel adrenocorticotropin-inducible cytochrome P450 from rat adrenal microsomes catalyzes polycylic aromatic hydrocarbon metabolism
-
S. Otto, C. Marcus, C. Pidgeon, and C. Jefcoate: A novel adrenocorticotropin-inducible cytochrome P450 from rat adrenal microsomes catalyzes polycylic aromatic hydrocarbon metabolism. Endocrinology 129, 970-982 (1991).
-
(1991)
Endocrinology
, vol.129
, pp. 970-982
-
-
Otto, S.1
Marcus, C.2
Pidgeon, C.3
Jefcoate, C.4
-
58
-
-
0026764146
-
Detection of human lung cytochromes P450 that are immunochemically related to cytochrome P450IIE1 and cytochrome P450IIIA
-
C. W. Wheeler, S. A. Wrighton, and T. M. Guenthner: Detection of human lung cytochromes P450 that are immunochemically related to cytochrome P450IIE1 and cytochrome P450IIIA. Biochem. Pharmacol. 44, 183-186 (1992).
-
(1992)
Biochem. Pharmacol.
, vol.44
, pp. 183-186
-
-
Wheeler, C.W.1
Wrighton, S.A.2
Guenthner, T.M.3
-
59
-
-
0026496023
-
Rat pulmonary microsomal cytochrome P-450 enzymes involved in the activation of procarcinogens
-
T. Shimada, H. Yamazaki, M. Mimura, and F. P. Guengerich: Rat pulmonary microsomal cytochrome P-450 enzymes involved in the activation of procarcinogens. Mutat. Res. 284, 233-241 (1992).
-
(1992)
Mutat. Res.
, vol.284
, pp. 233-241
-
-
Shimada, T.1
Yamazaki, H.2
Mimura, M.3
Guengerich, F.P.4
|