-
1
-
-
0033579358
-
Gene therapy death prompts review of adenovirus vector
-
Marshell E. Gene therapy death prompts review of adenovirus vector. Science 1999; 26:2244-2245.
-
(1999)
Science
, vol.26
, pp. 2244-2245
-
-
Marshell, E.1
-
2
-
-
0033957264
-
P53 Gene status modulates the chemosensitivity of non-small cell lung cancer cells
-
Lai SL, Perng RP, Hwang J. p53 Gene status modulates the chemosensitivity of non-small cell lung cancer cells. J Biomed Sci 2000; 7:64-70.
-
(2000)
J Biomed Sci
, vol.7
, pp. 64-70
-
-
Lai, S.L.1
Perng, R.P.2
Hwang, J.3
-
3
-
-
0034616629
-
Immunomodulatory gene Therapy with interleukin 12 and 4-1BB ligand: Long-term remission of liver metastates in a mouse model
-
Martinet O, Ermekova V, Qiao JQ, Sauter B, Mandeli J, Chen L, Chen SH. Immunomodulatory gene Therapy with interleukin 12 and 4-1BB ligand: long-term remission of liver metastates in a mouse model. J Natl Cancer Inst 2000; 92:931-936.
-
(2000)
J Natl Cancer Inst
, vol.92
, pp. 931-936
-
-
Martinet, O.1
Ermekova, V.2
Qiao, J.Q.3
Sauter, B.4
Mandeli, J.5
Chen, L.6
Chen, S.H.7
-
4
-
-
0033975328
-
Sensible use of antisense: How to use oligonucleotides as research tools
-
Myers KJ, Dean NM. Sensible use of antisense: how to use oligonucleotides as research tools. Trends Pharmacol Sci 2000; 21:19-23.
-
(2000)
Trends Pharmacol Sci
, vol.21
, pp. 19-23
-
-
Myers, K.J.1
Dean, N.M.2
-
5
-
-
0034176085
-
Elucidating cell signaling mechanisms using antisense technology
-
Koller E, Gaarde WA, Monia BP. Elucidating cell signaling mechanisms using antisense technology. Trends Pharmacol Sci 2000; 21:142-148.
-
(2000)
Trends Pharmacol Sci
, vol.21
, pp. 142-148
-
-
Koller, E.1
Gaarde, W.A.2
Monia, B.P.3
-
6
-
-
0031770195
-
Potentiation of E7 antisense RNA-induced antitumor immunity by co-delivery of IL-12 gene in HPV16 DNA-positive mouse tumor
-
He YK, Lui VW, Baar J, Wang L, Shurin M, Almonte C, Watkins SC, Huang L. Potentiation of E7 antisense RNA-induced antitumor immunity by co-delivery of IL-12 gene in HPV16 DNA-positive mouse tumor. Gene Ther 1998; 5:1462-1471.
-
(1998)
Gene Ther
, vol.5
, pp. 1462-1471
-
-
He, Y.K.1
Lui, V.W.2
Baar, J.3
Wang, L.4
Shurin, M.5
Almonte, C.6
Watkins, S.C.7
Huang, L.8
-
7
-
-
0033975496
-
The potential of gene therapy in the treatment of hepatocellular carcinoma
-
Qian C, Drozdzik M, Caselmann WH, Prieto J. The potential of gene therapy in the treatment of hepatocellular carcinoma. J Hepatol 2000; 32:344-351.
-
(2000)
J Hepatol
, vol.32
, pp. 344-351
-
-
Qian, C.1
Drozdzik, M.2
Caselmann, W.H.3
Prieto, J.4
-
8
-
-
0031453248
-
The JUN kinase/stress-activated protein kinase pathway is required for epidermal growth factor stimulation of growth of human A549 lung carcinoma cells
-
Bost F, McKay R, Dean N, Mercola D. The JUN kinase/stress-activated protein kinase pathway is required for epidermal growth factor stimulation of growth of human A549 lung carcinoma cells. J Biol Chem 1997; 272:33422-33429.
-
(1997)
J Biol Chem
, vol.272
, pp. 33422-33429
-
-
Bost, F.1
McKay, R.2
Dean, N.3
Mercola, D.4
-
9
-
-
0033952237
-
Down-regulation of the insulin-like growth factor I receptor by antisense RNA can reverse the transformed phenotype of human cervical cancer cell lines
-
Nakamura K, Hongo A, Kodama J, Miyagi Y, Yoshinouchi M, Kudo T. Down-regulation of the insulin-like growth factor I receptor by antisense RNA can reverse the transformed phenotype of human cervical cancer cell lines. Cancer Res 2000; 60:760-765.
-
(2000)
Cancer Res
, vol.60
, pp. 760-765
-
-
Nakamura, K.1
Hongo, A.2
Kodama, J.3
Miyagi, Y.4
Yoshinouchi, M.5
Kudo, T.6
-
10
-
-
0031435653
-
Reversal of tumor-induced immunosuppression: A new approach to cancer therapy
-
Wojtowicz-Praga S. Reversal of tumor-induced immunosuppression: a new approach to cancer therapy. J Immunother 1997; 20:165-177.
-
(1997)
J Immunother
, vol.20
, pp. 165-177
-
-
Wojtowicz-Praga, S.1
-
12
-
-
0030902471
-
Selecting effective antisense reagents on combinatorial oligonucleotide arrays
-
Milner N, Mir KU, Southern EM. Selecting effective antisense reagents on combinatorial oligonucleotide arrays. Nat Biotechnol 1997; 15:537-541.
-
(1997)
Nat Biotechnol
, vol.15
, pp. 537-541
-
-
Milner, N.1
Mir, K.U.2
Southern, E.M.3
-
13
-
-
0003038882
-
Mapping of RNA accessible sites for antisense experiments with oligonucleotide libraries
-
Ho SP, Bao Y, Lesher T, Malhotra R, Ma LY, Fluharty SJ, Sakai RR. Mapping of RNA accessible sites for antisense experiments with oligonucleotide libraries. Nat Biotechnol 1998; 16:59-63.
-
(1998)
Nat Biotechnol
, vol.16
, pp. 59-63
-
-
Ho, S.P.1
Bao, Y.2
Lesher, T.3
Malhotra, R.4
Ma, L.Y.5
Fluharty, S.J.6
Sakai, R.R.7
-
14
-
-
0034986068
-
Specific down-regulation of HER-2/neu mediated by a chimeric U6 hammerhead ribozyme results in growth inhibition of human ovarian carcinoma
-
Lui VW, He Y, Huang L. Specific down-regulation of HER-2/neu mediated by a chimeric U6 hammerhead ribozyme results in growth inhibition of human ovarian carcinoma. Mol Ther 2001; 3(2):169-177.
-
(2001)
Mol Ther
, vol.3
, Issue.2
, pp. 169-177
-
-
Lui, V.W.1
He, Y.2
Huang, L.3
-
15
-
-
0034017475
-
ERbB-2 expression is, rate-limiting for epidermal growth factor-mediated stimulation of ovarian cancer cell proliferation
-
Hsieh SS, Malerczyk C, Aigner A, Czubayko F. ERbB-2 expression is, rate-limiting for epidermal growth factor-mediated stimulation of ovarian cancer cell proliferation. Int J Cancer 2000; 86:644-651.
-
(2000)
Int J Cancer
, vol.86
, pp. 644-651
-
-
Hsieh, S.S.1
Malerczyk, C.2
Aigner, A.3
Czubayko, F.4
-
16
-
-
0032718015
-
Ribo-zyme-mediated down-regulation of ErbB-4 in estrogen receptor- positive breast cancer cells inhibits proliferation both in vitro and in vivo
-
Tang CK, Concepcion XZ, Milan M, Gong X, Montgomery E, Lippman ME. Ribo-zyme-mediated down-regulation of ErbB-4 in estrogen receptor- positive breast cancer cells inhibits proliferation both in vitro and in vivo. Cancer Res 1999; 59: 5315-5322.
-
(1999)
Cancer Res
, vol.59
, pp. 5315-5322
-
-
Tang, C.K.1
Concepcion, X.Z.2
Milan, M.3
Gong, X.4
Montgomery, E.5
Lippman, M.E.6
-
17
-
-
0034128434
-
Anti-K-ras ribozyme induces growth inhibition and increased chemosensitivity in human colon cancer cells
-
Funato T, Ishii T, Kambe M, Scanlon KJ, Sasaki T. Anti-K-ras ribozyme induces growth inhibition and increased chemosensitivity in human colon cancer cells. Cancer Gene Ther 2000; 7:495-500.
-
(2000)
Cancer Gene Ther
, vol.7
, pp. 495-500
-
-
Funato, T.1
Ishii, T.2
Kambe, M.3
Scanlon, K.J.4
Sasaki, T.5
-
18
-
-
0033964013
-
Marked inhibition of glioblastoma target cell tumorigenicity in vitro by retrovirus-mediated transfer of a hairpin ribozyme against deletion-mutant epidermal growth factor receptor messenger RNA
-
Halatsch ME, Schmidt U, Botefur IC, Holland JF, Ohnuma T. Marked inhibition of glioblastoma target cell tumorigenicity in vitro by retrovirus-mediated transfer of a hairpin ribozyme against deletion-mutant epidermal growth factor receptor messenger RNA. J Neurosurg 2000; 92:297-305.
-
(2000)
J Neurosurg
, vol.92
, pp. 297-305
-
-
Halatsch, M.E.1
Schmidt, U.2
Botefur, I.C.3
Holland, J.F.4
Ohnuma, T.5
-
19
-
-
0032990503
-
Ribozyme inhibition of the protein kinase C alpha triggers apoptosis in glioma cells
-
Leirdal M, Sioud M. Ribozyme inhibition of the protein kinase C alpha triggers apoptosis in glioma cells. Br J Cancer 1999; 80:1558-1564.
-
(1999)
Br J Cancer
, vol.80
, pp. 1558-1564
-
-
Leirdal, M.1
Sioud, M.2
-
20
-
-
0031821068
-
Ribozymes to the rescue: Repairing genetically defective mRNAs
-
Rossi JJ. Ribozymes to the rescue: repairing genetically defective mRNAs. Trends Genet 1998; 14:295-295.
-
(1998)
Trends Genet
, vol.14
, pp. 295
-
-
Rossi, J.J.1
-
21
-
-
0001787236
-
An introduciton to PNA
-
Nielsen PE, Egholm M, eds., Wymondhan, UK: Horizon Scientific Press
-
Nielsen PE, Egholm M. An introduciton to PNA. In: Nielsen PE, Egholm M, eds. Peptide Nucleic Acids: Protocols and Applications. Wymondhan, UK: Horizon Scientific Press, 1999, p 1-19.
-
(1999)
Peptide Nucleic Acids: Protocols and Applications
, pp. 1-19
-
-
Nielsen, P.E.1
Egholm, M.2
-
22
-
-
0342352059
-
Interactions of peptide nucleic acids with DNA processing enzymes
-
Nielsen PE, Egholm M, eds., Wyomondham, UK: Horizon Scientific Press
-
Raney KD, Hamilton SE, Corey DR. Interactions of peptide nucleic acids with DNA processing enzymes. In: Nielsen PE, Egholm M, eds. Peptide Nucleic Acids: Protocols and Applications. Wyomondham, UK: Horizon Scientific Press, 1999; pp 241-251.
-
(1999)
Peptide Nucleic Acids: Protocols and Applications
, pp. 241-251
-
-
Raney, K.D.1
Hamilton, S.E.2
Corey, D.R.3
-
23
-
-
0342786947
-
Antisense effects in Escherichia coli
-
Nielsen PE, Egholm M, eds, Wymondham, UK: Horizon Scientific Press
-
Good L, Nielsen PE. Antisense effects in Escherichia coli. In: Nielsen PE, Egholm M, eds. Peptide Nucleic Acids: Protocols and Applications. Wymondham, UK: Horizon Scientific Press, 1999, pp 213-220.
-
(1999)
Peptide Nucleic Acids: Protocols and Applications
, pp. 213-220
-
-
Good, L.1
Nielsen, P.E.2
-
24
-
-
0033524004
-
Telomerase inhibition by peptide nucleic acids reverses ‘immortality’ of transformed human cells
-
Shammas MA, Simmons CG, Corey DR, Reis RJ. Telomerase inhibition by peptide nucleic acids reverses ‘immortality’ of transformed human cells. Oncogene 1999; 18:6191-6200.
-
(1999)
Oncogene
, vol.18
, pp. 6191-6200
-
-
Shammas, M.A.1
Simmons, C.G.2
Corey, D.R.3
Reis, R.J.4
-
25
-
-
0030059301
-
Mutagenesis in mammalian cells induced by triple helix formation and transcription-coupled repair
-
Wang G, Seidman MM, Glazer PM. Mutagenesis in mammalian cells induced by triple helix formation and transcription-coupled repair. Science 1996; 271:802-805.
-
(1996)
Science
, vol.271
, pp. 802-805
-
-
Wang, G.1
Seidman, M.M.2
Glazer, P.M.3
-
26
-
-
0033557144
-
Chromosomal mutations induced by triplex-forming oligonucleotides in mammalian cells
-
Vasquez KM, Wang G, Havre PA, Glazer PM. Chromosomal mutations induced by triplex-forming oligonucleotides in mammalian cells. Nucleic Acids Res 1999; 27:1176-1181.
-
(1999)
Nucleic Acids Res
, vol.27
, pp. 1176-1181
-
-
Vasquez, K.M.1
Wang, G.2
Havre, P.A.3
Glazer, P.M.4
-
27
-
-
0025744428
-
Evidence that a triplex-forming oligo-deoxyribonucleotide binds to the c- myc promoter in HeLa cells, thereby reducing c-myc mRNA levels
-
Postel EH, Flint SJ, Kessler DJ, Hogan ME. Evidence that a triplex-forming oligo-deoxyribonucleotide binds to the c- myc promoter in HeLa cells, thereby reducing c-myc mRNA levels. Proc Natl Acad Sci USA 1991; 88:8227-8231.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 8227-8231
-
-
Postel, E.H.1
Flint, S.J.2
Kessler, D.J.3
Hogan, M.E.4
-
28
-
-
0034724438
-
Unambiguous demonstration of triple-helix-directed gene modification
-
Barre FX, Ait-Si-Ali S, Giovannangeli C, Luis R, Robin P, Pritchard LL, Helene C, Harel-Bellan A. Unambiguous demonstration of triple-helix-directed gene modification. Proc Natl Acad Sci USA 2000; 97:3084-3088.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 3084-3088
-
-
Barre, F.X.1
Ait-Si-Ali, S.2
Giovannangeli, C.3
Luis, R.4
Robin, P.5
Pritchard, L.L.6
Helene, C.7
Harel-Bellan, A.8
-
29
-
-
0029797724
-
Specific inhibition of in vitro transcription elongation by triplex- forming oligonucleotide-intercalator conjugates targeted to HIV proviral DNA
-
Giovannangeli C, Perrouault L, Escude C, Nguyen T, Helene C. Specific inhibition of in vitro transcription elongation by triplex- forming oligonucleotide-intercalator conjugates targeted to HIV proviral DNA. Biochemistry 1996; 35:10539-10548.
-
(1996)
Biochemistry
, vol.35
, pp. 10539-10548
-
-
Giovannangeli, C.1
Perrouault, L.2
Escude, C.3
Nguyen, T.4
Helene, C.5
-
30
-
-
0031149794
-
A 15-base acridine conjugatedoligodeoxynucleotide forms triplex DNA with its IL-2R alpha promoter target withgreatly improved avidity
-
Klysik J, Kinsey BM, Hua P, Glass GA, Orson FM. A 15-base acridine conjugated oligodeoxynucleotide forms triplex DNA with its IL-2R alpha promoter target with greatly improved avidity. Bioconjug Chem 1997; 8:318-326.
-
(1997)
Bioconjug Chem
, vol.8
, pp. 318-326
-
-
Klysik, J.1
Kinsey, B.M.2
Hua, P.3
Glass, G.A.4
Orson, F.M.5
-
31
-
-
0027999873
-
Triplex formation at the rat neu oncogene promoter
-
Gee JE, Yen RL, Hung M-C, Hogan ME. Triplex formation at the rat neu oncogene promoter. Gene 1994; 149:109-114.
-
(1994)
Gene
, vol.149
, pp. 109-114
-
-
Gee, J.E.1
Yen, R.L.2
Hung, M.-C.3
Hogan, M.E.4
-
33
-
-
0032774070
-
A role for intracellular immunization in chemosensitization of tumor cells?
-
Piche A, Rancourt C. A role for intracellular immunization in chemosensitization of tumor cells? Gene Ther 1999; 6:1202-1209.
-
(1999)
Gene Ther
, vol.6
, pp. 1202-1209
-
-
Piche, A.1
Rancourt, C.2
-
34
-
-
0000035666
-
Targeting HER-2/neu-overexpressing cancer cells with transcriptional repressor genes delivered by cationic liposome
-
Huang L, Hung MC, Wagner E, eds., San Diego Academic Press
-
Hung MC, Wang SC, Hortobagyi G. Targeting HER-2/neu-overexpressing cancer cells with transcriptional repressor genes delivered by cationic liposome. In: Huang L, Hung MC, Wagner E, eds. Nonviral Vectors for Gene Therapy. San Diego Academic Press, 1999, pp 357-377.
-
(1999)
Nonviral Vectors for Gene Therapy
, pp. 357-377
-
-
Hung, M.C.1
Wang, S.C.2
Hortobagyi, G.3
-
35
-
-
0031816634
-
The erbB2 gene as a cancer therapeutic target and the tumor-and metastasis-supressing function of E1A
-
Yu D, Hung M-C. The erbB2 gene as a cancer therapeutic target and the tumor-and metastasis-supressing function of E1A. Cancer Metastasis Rev 1998; 17:195-202.
-
(1998)
Cancer Metastasis Rev
, vol.17
, pp. 195-202
-
-
Yu, D.1
Hung, M.-C.2
-
36
-
-
0027944206
-
Jacks T. P53 status and the efficacy of cancer therapy in vivo
-
Lowe SW, Bodis S, McClatchey A, Remington L, Ruley HE, Fisher DE, Housman DE, Jacks T. p53 status and the efficacy of cancer therapy in vivo. Science 1994; 266:807-810.
-
(1994)
Science
, vol.266
, pp. 807-810
-
-
Lowe, S.W.1
Bodis, S.2
McClatchey, A.3
Remington, L.4
Ruley, H.E.5
Fisher, D.E.6
Housman, D.E.7
-
37
-
-
0032851758
-
Progress in cancer gene therapy
-
Kouraklis G. Progress in cancer gene therapy. Acta Oncol 1999; 38:675-683.
-
(1999)
Acta Oncol
, vol.38
, pp. 675-683
-
-
Kouraklis, G.1
-
38
-
-
0031750168
-
Adenovirus-mediated p53 gene transfer in patients with advanced recurrent head and neck squamous cell carcinoma
-
Clayman GL, el-Naggar AK, Lippman SM, Henderson YC, Frederick M, Merritt JA, Zumstein LA, Timmons TM, Liu TJ, Ginsberg L, Roth JA, Hong WK, Bruso P, Goepfert H. Adenovirus-mediated p53 gene transfer in patients with advanced recurrent head and neck squamous cell carcinoma. J Clin Oncol 1998; 16:2221-2232.
-
(1998)
J Clin Oncol
, vol.16
, pp. 2221-2232
-
-
Clayman, G.L.1
El-Naggar, A.K.2
Lippman, S.M.3
Henderson, Y.C.4
Frederick, M.5
Merritt, J.A.6
Zumstein, L.A.7
Timmons, T.M.8
Liu, T.J.9
Ginsberg, L.10
Roth, J.A.11
Hong, W.K.12
Bruso, P.13
Goepfert, H.14
-
39
-
-
0031828108
-
Gene therapy for nonsmall cell lung cancer: A preliminary report of a phase I trial of adenoviral p53 gene replacement
-
Roth JA, Swisher SG, Merritt JA, Lawrence DD, Kemp BL, Carrasco CH, El-Naggar AK, Fossella FV, Glisson BS, Hong WK, Khurl FR, Kurie JM, Nesbitt JC, Pisters K, Putnam JB, Schrump DS, Shin DM, Walsh GL. Gene therapy for nonsmall cell lung cancer: a preliminary report of a phase I trial of adenoviral p53 gene replacement. Semin Oncol 1998; 25:33-37.
-
(1998)
Semin Oncol
, vol.25
, pp. 33-37
-
-
Roth, J.A.1
Swisher, S.G.2
Merritt, J.A.3
Lawrence, D.D.4
Kemp, B.L.5
Carrasco, C.H.6
El-Naggar, A.K.7
Fossella, F.V.8
Glisson, B.S.9
Hong, W.K.10
Khurl, F.R.11
Kurie, J.M.12
Nesbitt, J.C.13
Pisters, K.14
Putnam, J.B.15
Schrump, D.S.16
Shin, D.M.17
Walsh, G.L.18
-
40
-
-
0032779935
-
Molecular regulation of cell death and therapeutic strategies for cell death induction in prostate carcinoma
-
Gjertsen BT, Logothetis CL, McDonnell TJ. Molecular regulation of cell death and therapeutic strategies for cell death induction in prostate carcinoma. Cancer Metastasis Rev 1999; 17:345-351.
-
(1999)
Cancer Metastasis Rev
, vol.17
, pp. 345-351
-
-
Gjertsen, B.T.1
Logothetis, C.L.2
McDonnell, T.J.3
-
41
-
-
0034113017
-
Exogenous mutant p53 DNA enhanced cisplatin-induced apoptosis in TSGH- 8301 human bladder cancer cells
-
Chang FL, Ling YF, Lai MD. Exogenous mutant p53 DNA enhanced cisplatin-induced apoptosis in TSGH- 8301 human bladder cancer cells. Anticancer Res 2000; 20:329-336.
-
(2000)
Anticancer Res
, vol.20
, pp. 329-336
-
-
Chang, F.L.1
Ling, Y.F.2
Lai, M.D.3
-
42
-
-
0030614944
-
Adenovirally transferred p161NK4/CDKN2 and p53 genes cooperate to induce apoptotic tumor cell death
-
Sandig V, Brand K, Herwig S, Lukas J, Bartek J, Strauss M. Adenovirally transferred p161NK4/CDKN2 and p53 genes cooperate to induce apoptotic tumor cell death. Nat Med 1997; 3:313-319.
-
(1997)
Nat Med
, vol.3
, pp. 313-319
-
-
Sandig, V.1
Brand, K.2
Herwig, S.3
Lukas, J.4
Bartek, J.5
Strauss, M.6
-
43
-
-
0033393502
-
Cancer gene therapy using a pro-apoptosic gene, caspase-3
-
Yamabe K, Shimizu S, Ito T, Yoshioka Y, Nomura M, Narita M, Saito I, Kanegae Y, Matsuda H. Cancer gene therapy using a pro-apoptosic gene, caspase-3. Gene Ther 1999; 6:1952-1959.
-
(1999)
Gene Ther
, vol.6
, pp. 1952-1959
-
-
Yamabe, K.1
Shimizu, S.2
Ito, T.3
Yoshioka, Y.4
Nomura, M.5
Narita, M.6
Saito, I.7
Kanegae, Y.8
Matsuda, H.9
-
44
-
-
0033034218
-
Adenovirus-mediated p21((WAF1/SDII/CIP1)) gene transfer induces apoptosis of human cervical cancer cell lines
-
Tsao YP, Huang SJ, Chang JL, Hsieh JT, Pong RC, Chen SL. Adenovirus-mediated p21((WAF1/SDII/CIP1)) gene transfer induces apoptosis of human cervical cancer cell lines. J Virol 1999; 73:4983-4890.
-
(1999)
J Virol
, vol.73
, pp. 4983
-
-
Tsao, Y.P.1
Huang, S.J.2
Chang, J.L.3
Hsieh, J.T.4
Pong, R.C.5
Chen, S.L.6
-
45
-
-
0030888664
-
BCL-2 antisense therapy in patients with non-Hodgkin lymphoma
-
Webb A, Cunningham D, Cotter F, Clarke PA, di Stefano F, Ross P, Corbo M, Dziewanowska Z. BCL-2 antisense therapy in patients with non-Hodgkin lymphoma. Lancet 1997; 349:1137-1141.
-
(1997)
Lancet
, vol.349
, pp. 1137-1141
-
-
Webb, A.1
Cunningham, D.2
Cotter, F.3
Clarke, P.A.4
Di Stefano, F.5
Ross, P.6
Corbo, M.7
Dziewanowska, Z.8
-
46
-
-
0030822629
-
Development of a hammerhead ribozyme against bcl-2. I. Preliminary evaluation of a potential gene therapeutic agent for hormone refractory human prostate cancer
-
Dorai T, Olsson CA, Katz AE, Buttyan R. Development of a hammerhead ribozyme against bcl-2. I. Preliminary evaluation of a potential gene therapeutic agent for hormone refractory human prostate cancer. Prostate 1997; 32:246-258.
-
(1997)
Prostate
, vol.32
, pp. 246-258
-
-
Dorai, T.1
Olsson, C.A.2
Katz, A.E.3
Buttyan, R.4
-
47
-
-
0032523945
-
Modulation of Bcl-2 protein levels by an intracellular anti-Bcl-2 single-chain antibody increases drug-induced cytotoxicity in the breast cancer cell line MCF-7
-
Piche A, Grim J, Rancourt C, Gomez-Navarro J, Reed JC, Curiel DT. Modulation of Bcl-2 protein levels by an intracellular anti-Bcl-2 single-chain antibody increases drug-induced cytotoxicity in the breast cancer cell line MCF-7. Cancer Res 1998; 58:2134-2140.
-
(1998)
Cancer Res
, vol.58
, pp. 2134-2140
-
-
Piche, A.1
Grim, J.2
Rancourt, C.3
Gomez-Navarro, J.4
Reed, J.C.5
Curiel, D.T.6
-
48
-
-
0017100861
-
Relation of vascular proliferation to tumor growth
-
Folkman J, Cotran R. Relation of vascular proliferation to tumor growth. Int Rev Exp Pathol 1976; 16:207-248.
-
(1976)
Int Rev Exp Pathol
, vol.16
, pp. 207-248
-
-
Folkman, J.1
Cotran, R.2
-
49
-
-
0031667546
-
Targeting angiogenesis: Genetic intervention which strikes at the weak link of tumorigenesis [editorial]
-
Taniguchi T, Rigg A, Lemoine NR. Targeting angiogenesis: genetic intervention which strikes at the weak link of tumorigenesis [editorial]. Gene Ther 1998; 5: 1011-1013.
-
(1998)
Gene Ther
, vol.5
, pp. 1011-1013
-
-
Taniguchi, T.1
Rigg, A.2
Lemoine, N.R.3
-
50
-
-
0032530218
-
Tumor growth modulation by sense and antisense vascular endothelial growth factor gene expression: Effects on angiogenesis, vascular permeability, blood volume, blood flow, fluorodeoxyglucose uptake, proliferation of human melanoma intracerebral xenografts
-
Oku T, Tjuvajev JG, Miyagawa T, Sasajima T, Joshi A, Joshi R, Finn R, Claffey KP, Blasberg RG. Tumor growth modulation by sense and antisense vascular endothelial growth factor gene expression: effects on angiogenesis, vascular permeability, blood volume, blood flow, fluorodeoxyglucose uptake, proliferation of human melanoma intracerebral xenografts. Cancer Res 1998; 58:4185-4192.
-
(1998)
Cancer Res
, vol.58
, pp. 4185-4192
-
-
Oku, T.1
Tjuvajev, J.G.2
Miyagawa, T.3
Sasajima, T.4
Joshi, A.5
Joshi, R.6
Finn, R.7
Claffey, K.P.8
Blasberg, R.G.9
-
51
-
-
0034069028
-
Antitumor and antimetastatic activity of ribozymes targeting the messenger RNA of vascular endothelial growth factor receptors
-
Pavco PA, Bouhana KS, Gallegos AM, Agrawal A, Blanchard KS, Grimm SL, Jensen KL, Andrews LE, Wincott FE, Pitot PA, Tressler RJ, Cushman C, Reynolds MA, Parry TJ. Antitumor and antimetastatic activity of ribozymes targeting the messenger RNA of vascular endothelial growth factor receptors. Clin Cancer Res 2000; 6:2094-2103.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 2094-2103
-
-
Pavco, P.A.1
Bouhana, K.S.2
Gallegos, A.M.3
Agrawal, A.4
Blanchard, K.S.5
Grimm, S.L.6
Jensen, K.L.7
Rews, L.E.8
Wincott, F.E.9
Pitot, P.A.10
Tressler, R.J.11
Cushman, C.12
Reynolds, M.A.13
Parry, T.J.14
-
52
-
-
0034657404
-
Liposome-delivered angiostatin strongly inhibits tumor growth and metastatization in a transgenic model of spontaneous breast cancer
-
Sacco MG, Caniatti M, Cato EM, Frattini A, Chiesa G, Ceruti R, Adorni F, Zecca L, Scanziani E, Vezzoni P. Liposome-delivered angiostatin strongly inhibits tumor growth and metastatization in a transgenic model of spontaneous breast cancer. Cancer Res 2000; 60:2660-2665.
-
(2000)
Cancer Res
, vol.60
, pp. 2660-2665
-
-
Sacco, M.G.1
Caniatti, M.2
Cato, E.M.3
Frattini, A.4
Chiesa, G.5
Ceruti, R.6
Adorni, F.7
Zecca, L.8
Scanziani, E.9
Vezzoni, P.10
-
53
-
-
0032031748
-
Expression of angiostatin cDNA in a murine fibrosarcoma suppresses primary tumor growth and produces long-term dormancy of metastases [published erratum appears
-
1998 Dec 1; 102(11):2031]. J Clin Invest 1998
-
Cao Y, O’Reilly MS, Marshall B, Flynn E, Ji RW, Folkman J. Expression of angiostatin cDNA in a murine fibrosarcoma suppresses primary tumor growth and produces long-term dormancy of metastases [published erratum appears J Clin Invest 1998 Dec 1; 102(11):2031]. J Clin Invest 1998; 101:1055-1063.
-
J Clin Invest
, vol.101
, pp. 1055-1063
-
-
Cao, Y.1
O’Reilly, M.S.2
Marshall, B.3
Flynn, E.4
Ji, R.W.5
Folkman, J.6
-
54
-
-
0030887423
-
Expression of the nm23 metastasis-suppressor gene product in skin tumors
-
Kanitakis J, Euvrard S, Bourchany D, Faure M, Claudy A. Expression of the nm23 metastasis-suppressor gene product in skin tumors. J Cutan Pathol 1997; 24:151-156.
-
(1997)
J Cutan Pathol
, vol.24
, pp. 151-156
-
-
Kanitakis, J.1
Euvrard, S.2
Bourchany, D.3
Faure, M.4
Claudy, A.5
-
55
-
-
0343294335
-
AAC-11 overexpression induces invasion and protects cervical cancer cells from apoptosis
-
Kim JW, Cho HS, Kim JH, Hur SY, Kim TE, Lee JM, Kim IK, Namkoong SE. AAC-11 overexpression induces invasion and protects cervical cancer cells from apoptosis. Lab Invest 2000; 80:587-594.
-
(2000)
Lab Invest
, vol.80
, pp. 587-594
-
-
Kim, J.W.1
Cho, H.S.2
Kim, J.H.3
Hur, S.Y.4
Kim, T.E.5
Lee, J.M.6
Kim, I.K.7
Namkoong, S.E.8
-
56
-
-
0027517321
-
Direct gene transfer with DNA-liposome complexes in melanoma: Expression, biologic activity, and lack of toxicity in humans
-
Nabel GJ, Nabel EG, Yang ZY, Fox BA, Plautz GE, Gao X, Huang L, Shu S, Gordon D, Chang AE. Direct gene transfer with DNA-liposome complexes in melanoma: expression, biologic activity, and lack of toxicity in humans. Proc Natl Acad Sci USA 1993; 90:11307-11311.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 11307-11311
-
-
Nabel, G.J.1
Nabel, E.G.2
Yang, Z.Y.3
Fox, B.A.4
Plautz, G.E.5
Gao, X.6
Huang, L.7
Shu, S.8
Gordon, D.9
Chang, A.E.10
-
57
-
-
0034068643
-
TAP expression provides a general method for improving the recognition of malignant cells in vivo
-
Alimonti J, Zhang QJ, Gabathuler R, Reid G, Chen SS, Jefferies WA. TAP expression provides a general method for improving the recognition of malignant cells in vivo. Nat Biotechnol 2000; 18:515-520.
-
(2000)
Nat Biotechnol
, vol.18
, pp. 515-520
-
-
Alimonti, J.1
Zhang, Q.J.2
Gabathuler, R.3
Reid, G.4
Chen, S.S.5
Jefferies, W.A.6
-
58
-
-
0027310605
-
Functional and molecular characterization of tumor-infiltrating lymphocytes transduced with tumor necrosis factor-alpha cDNA for the gene therapy of cancer in humans
-
Hwu P, Yannelli J, Kriegler M, Anderson WF, Perez C, Chiang Y, Schwarz S, Cowherd R, Delgado C, Mule J, et al. Functional and molecular characterization of tumor-infiltrating lymphocytes transduced with tumor necrosis factor-alpha cDNA for the gene therapy of cancer in humans. J Immunol 1993; 150:4104-4115.
-
(1993)
J Immunol
, vol.150
, pp. 4104-4115
-
-
Hwu, P.1
Yannelli, J.2
Kriegler, M.3
Erson, W.F.4
Perez, C.5
Chiang, Y.6
Schwarz, S.7
Cowherd, R.8
Delgado, C.9
Mule, J.10
-
59
-
-
0034111112
-
Macrophage inflammatory protein 3alpha transgene attracts dendritic cells to established murine tumors and suppresses tumor growth
-
Fushimi T, Kojima A, Moore MA, Crystal RG. Macrophage inflammatory protein 3alpha transgene attracts dendritic cells to established murine tumors and suppresses tumor growth. J Clin Invest 2000; 105:1383-1393.
-
(2000)
J Clin Invest
, vol.105
, pp. 1383-1393
-
-
Fushimi, T.1
Kojima, A.2
Moore, M.A.3
Crystal, R.G.4
-
60
-
-
0034192391
-
Cytokine gene therapy gliomas: Induction of reactive CD4+ T cells by interleukin-4- transferred 9L gliosarcoma is essential for protective immunity
-
Giezeman-Smits KM, Okada H, Brissette-Storkus CS, Villa LA, Attanucci J, Lotze MT, Pollack IF, Bozik ME, Chambers WH. Cytokine gene therapy gliomas: induction of reactive CD4+ T cells by interleukin-4- transferred 9L gliosarcoma is essential for protective immunity. Cancer Res 2000; 60:2449-2457.
-
(2000)
Cancer Res
, vol.60
, pp. 2449-2457
-
-
Giezeman-Smits, K.M.1
Okada, H.2
Brissette-Storkus, C.S.3
Villa, L.A.4
Attanucci, J.5
Lotze, M.T.6
Pollack, I.F.7
Bozik, M.E.8
Chambers, W.H.9
-
61
-
-
0025095664
-
Interleukin-2 production by tumor cells bypasses T helper function in the generation of an antitumor response
-
Fearon ER, Pardoll DM, Itaya T, Golumbek P, Levitsky HI, Simons JW, Karasuyama H, Vogelstein B, Frost P. Interleukin-2 production by tumor cells bypasses T helper function in the generation of an antitumor response. Cell 1990; 60:397-403.
-
(1990)
Cell
, vol.60
, pp. 397-403
-
-
Fearon, E.R.1
Pardoll, D.M.2
Itaya, T.3
Golumbek, P.4
Levitsky, H.I.5
Simons, J.W.6
Karasuyama, H.7
Vogelstein, B.8
Frost, P.9
-
62
-
-
0025604195
-
Retroviral vector-mediated gamma-interferon gene transfer into tumor cells generates potent and long lasting antitumor immunity
-
Gansbacher B, Bannerji R, Daniels B, Zier K, Cronin K, Gilboa E. Retroviral vector-mediated gamma-interferon gene transfer into tumor cells generates potent and long lasting antitumor immunity. Cancer Res 1990; 50:7820-7825.
-
(1990)
Cancer Res
, vol.50
, pp. 7820-7825
-
-
Gansbacher, B.1
Bannerji, R.2
Daniels, B.3
Zier, K.4
Cronin, K.5
Gilboa, E.6
-
63
-
-
0027298471
-
Antimetastatic vaccination of tumor-bearing mice with two types of IFN-gamma geneinserted tumor cells
-
Porgador A, Bannerji R, Watanabe Y, Feldman M, Gilboa E, Eisenbach L. Antimetastatic vaccination of tumor-bearing mice with two types of IFN-gamma geneinserted tumor cells. J Immunol 1993; 150:1458-1470.
-
(1993)
J Immunol
, vol.150
, pp. 1458-1470
-
-
Porgador, A.1
Bannerji, R.2
Watanabe, Y.3
Feldman, M.4
Gilboa, E.5
Eisenbach, L.6
-
64
-
-
0034024202
-
Tumor cells expressing membrane-bound form of IL-4 induce antitumor immunity
-
Kim YS, Sonn CH, Bothwell ALM. Tumor cells expressing membrane-bound form of IL-4 induce antitumor immunity. Gene Therapy 2000; 7:837-843.
-
(2000)
Gene Therapy
, vol.7
, pp. 837-843
-
-
Kim, Y.S.1
Sonn, C.H.2
Bothwell, A.L.M.3
-
65
-
-
0033218093
-
Regional treatment of hepatic micrometastasis by adenovirus vector-mediated delivery of interleukin-2 and interleukin-12 cDNAs to the hepatic parenchyma
-
Hirschowitz EA, Naama HA, Evoy D, Lieberman MD, Daly J, Crystal RG. Regional treatment of hepatic micrometastasis by adenovirus vector-mediated delivery of interleukin-2 and interleukin-12 cDNAs to the hepatic parenchyma. Cancer Gene Ther 1999; 6:491-498.
-
(1999)
Cancer Gene Ther
, vol.6
, pp. 491-498
-
-
Hirschowitz, E.A.1
Naama, H.A.2
Evoy, D.3
Lieberman, M.D.4
Daly, J.5
Crystal, R.G.6
-
66
-
-
0032589101
-
Efficient inducation of local and systemic antitumor immune response by liposome-mediated intratumoral co-transfer of interleukin-2 gene and interleukin-6 gene
-
Cao X, Wang Q, Ju DW, Tao Q, Wang J. Efficient inducation of local and systemic antitumor immune response by liposome-mediated intratumoral co-transfer of interleukin-2 gene and interleukin-6 gene. J Exp Clin Cancer Res 1999; 18:191-200.
-
(1999)
J Exp Clin Cancer Res
, vol.18
, pp. 191-200
-
-
Cao, X.1
Wang, Q.2
Ju, D.W.3
Tao, Q.4
Wang, J.5
-
67
-
-
0034105411
-
Antitumor effects on mouse melanoma elicited by local secretion of interleukin-12 and their enhancement by treatment with interleukin-18
-
Nagai H, Hara I, Horikawa T, Fujii M, Kurimoto M, Kamidono S, Ichihashi M. Antitumor effects on mouse melanoma elicited by local secretion of interleukin-12 and their enhancement by treatment with interleukin-18. Cancer Invest 2000; 18:206-213.
-
(2000)
Cancer Invest
, vol.18
, pp. 206-213
-
-
Nagai, H.1
Hara, I.2
Horikawa, T.3
Fujii, M.4
Kurimoto, M.5
Kamidono, S.6
Ichihashi, M.7
-
68
-
-
0027134873
-
Regulation of adhesion and adhesion molecules in endothelium by transforming growth factor-beta
-
Khew-Goodall Y, Gamble JR, Vadas MA. Regulation of adhesion and adhesion molecules in endothelium by transforming growth factor-beta. Currt Top Microbiol Immunol 1993; 184:187-199.
-
(1993)
Currt Top Microbiol Immunol
, vol.184
, pp. 187-199
-
-
Khew-Goodall, Y.1
Gamble, J.R.2
Vadas, M.A.3
-
69
-
-
0027569092
-
Transforming growth factor beta 1 can induce estrogen-independent tumorigenicity of human breast cancer cells in athymic mice
-
Arteaga CL, Carty-Dugger T, Moses HL, Hurd SD, Pietenpol JA. Transforming growth factor beta 1 can induce estrogen-independent tumorigenicity of human breast cancer cells in athymic mice. Cell Growth Differ 1993; 4:193-201.
-
(1993)
Cell Growth Differ
, vol.4
, pp. 193-201
-
-
Arteaga, C.L.1
Carty-Dugger, T.2
Moses, H.L.3
Hurd, S.D.4
Pietenpol, J.A.5
-
70
-
-
0027137485
-
Antitransforming growth factor (TGF)-beta antibodies inhibit breast cancer cell tumori-genicity and increase mouse spleen natural killer cell activity. Implications for a possible role of tumor cell/host TGF- beta interactions in human breast cancer progression
-
Arteaga CL, Hurd SD, Winnier AR, Johnson MD, Fendly BM, Forbes JT, Antitransforming growth factor (TGF)-beta antibodies inhibit breast cancer cell tumori-genicity and increase mouse spleen natural killer cell activity. Implications for a possible role of tumor cell/host TGF- beta interactions in human breast cancer progression. J Clin Invest 1993; 92:2569-2576.
-
(1993)
J Clin Invest
, vol.92
, pp. 2569-2576
-
-
Arteaga, C.L.1
Hurd, S.D.2
Winnier, A.R.3
Johnson, M.D.4
Fendly, B.M.5
Forbes, J.T.6
-
71
-
-
0029865486
-
Eradication of established intracranial rat gliomas by transforming growth factor beta antisense gene therapy
-
Fakhrai H, Dorigo O, Shawler DL, Lin H, Mercola D, Black KL, Royston I, Sobol RE. Eradication of established intracranial rat gliomas by transforming growth factor beta antisense gene therapy. Proc Natl Acad Sci USA 1996; 93:2909-2914.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 2909-2914
-
-
Fakhrai, H.1
Dorigo, O.2
Shawler, D.L.3
Lin, H.4
Mercola, D.5
Black, K.L.6
Royston, I.7
Sobol, R.E.8
-
72
-
-
0005021349
-
Particle-mediated gene delivery applications to canine and other larger animial systems
-
Huang L, Hung MC, Wagner E, eds., San Diego: Academic Press
-
Yang NS, Hogge GS, MacEwen EG. Particle-mediated gene delivery applications to canine and other larger animial systems. In: Huang L, Hung MC, Wagner E, eds. Nonviral Vectors for Gene Therapy. San Diego: Academic Press, 1999, pp 171-190.
-
(1999)
Nonviral Vectors for Gene Therapy
, pp. 171-190
-
-
Yang, N.S.1
Hogge, G.S.2
Macewen, E.G.3
-
73
-
-
0034155243
-
Induction of anti-tumor immunity by intrasplenic administration of a carcinoembry-onic antigen DNA vaccine
-
White SA, LoBuglio AF, Arani RB, Pike MJ, Moore SE, Barlow DL, Conry RM. Induction of anti-tumor immunity by intrasplenic administration of a carcinoembry-onic antigen DNA vaccine. J Gene Med 2000; 2:135-140.
-
(2000)
J Gene Med
, vol.2
, pp. 135-140
-
-
White, S.A.1
Lobuglio, A.F.2
Arani, R.B.3
Pike, M.J.4
Moore, S.E.5
Barlow, D.L.6
Conry, R.M.7
-
74
-
-
0033380078
-
Gene gun-mediated DNA vaccination induces antitumor immunity against human papillomavirus type 16 E7-expressing murine tumor metastases in the liver and lungs
-
Chen CH, Ji H, Suh KW, Choti MA, Pardoll DM, Wu TC. Gene gun-mediated DNA vaccination induces antitumor immunity against human papillomavirus type 16 E7-expressing murine tumor metastases in the liver and lungs. Gene Ther 1999; 6:1972-1981.
-
(1999)
Gene Ther
, vol.6
, pp. 1972-1981
-
-
Chen, C.H.1
Ji, H.2
Suh, K.W.3
Choti, M.A.4
Pardoll, D.M.5
Wu, T.C.6
-
76
-
-
2442770054
-
Coexpression of cytidine deaminase and mutant dihydrofolate reductase by a bicistronic retroviral vector confers resistance to cytosine arabinoside and methotrexate
-
Beausejour CM, Le NL, Letourneau S, Cournoyer D, Momparler RL. Coexpression of cytidine deaminase and mutant dihydrofolate reductase by a bicistronic retroviral vector confers resistance to cytosine arabinoside and methotrexate. Hum Gene Ther 1998; 9:2537-2544.
-
(1998)
Hum Gene Ther
, vol.9
, pp. 2537-2544
-
-
Beausejour, C.M.1
Le, N.L.2
Letourneau, S.3
Cournoyer, D.4
Momparler, R.L.5
-
77
-
-
0032873312
-
Folate-targeted enzyme prodrug cancer therapy utilizing penicillin-V amidase and a doxorubicin prodrug
-
Lu JY, Lowe DA, Kennedy MD, Low PS. Folate-targeted enzyme prodrug cancer therapy utilizing penicillin-V amidase and a doxorubicin prodrug. J Drug Target 1999; 7:43-53.
-
(1999)
J Drug Target
, vol.7
, pp. 43-53
-
-
Lu, J.Y.1
Lowe, D.A.2
Kennedy, M.D.3
Low, P.S.4
-
78
-
-
0034688260
-
Regressions of established breast carcinoma xenografts by carboxypeptidase G2 suicide gene therapy and the prodrug CMDA are due to a bystander effect
-
Stribbling SM, Friedlos F, Martin J, Davies L, Spooner RA, Marais R, Springer CJ. Regressions of established breast carcinoma xenografts by carboxypeptidase G2 suicide gene therapy and the prodrug CMDA are due to a bystander effect. Hum Gene Ther 2000; 11:285-292.
-
(2000)
Hum Gene Ther
, vol.11
, pp. 285-292
-
-
Stribbling, S.M.1
Friedlos, F.2
Martin, J.3
Davies, L.4
Spooner, R.A.5
Marais, R.6
Springer, C.J.7
-
79
-
-
0034087221
-
Expression of Escherichia coli uracil phosphoribosyltransferase gene in murine colon carcinoma cells augments the antitumoral effect of 5- fluorouracil and induces protective immunity
-
Kawamura K, Tasaki K, Hamada H, Takenaga K, Sakiyama S, Tagawa M. Expression of Escherichia coli uracil phosphoribosyltransferase gene in murine colon carcinoma cells augments the antitumoral effect of 5- fluorouracil and induces protective immunity. Cancer Gene Ther 2000; 7:637-643.
-
(2000)
Cancer Gene Ther
, vol.7
, pp. 637-643
-
-
Kawamura, K.1
Tasaki, K.2
Hamada, H.3
Takenaga, K.4
Sakiyama, S.5
Tagawa, M.6
-
80
-
-
0034181382
-
Use of the ornithine decarboxylase promoter to ahieve N-MYC-mediated overexpression of a rabbit carboxylesterase to sensitize neuroblastoma cells to CPT-11
-
Pawlik CA, Iyengar RV, Krull EJ, Mason SE, Khanna R, Harris LC, Potter PM, Danks MK, Guichard SM. Use of the ornithine decarboxylase promoter to ahieve N-MYC-mediated overexpression of a rabbit carboxylesterase to sensitize neuroblastoma cells to CPT-11. Mol Ther 2000; 1:457-463.
-
(2000)
Mol Ther
, vol.1
, pp. 457-463
-
-
Pawlik, C.A.1
Iyengar, R.V.2
Krull, E.J.3
Mason, S.E.4
Khanna, R.5
Harris, L.C.6
Potter, P.M.7
Danks, M.K.8
Guichard, S.M.9
-
82
-
-
0030757097
-
The bystander effect exerted by tumor cells expressing the herpes simplex virus thymidine kinase (HSVtk) gene is dependent on connexin expression and cell communication via gap junctions
-
Vrionis FD, Wu JK, Qi P, Waltzman M, Cherington V, Spray DC. The bystander effect exerted by tumor cells expressing the herpes simplex virus thymidine kinase (HSVtk) gene is dependent on connexin expression and cell communication via gap junctions. Gene Ther 1997; 4:577-585.
-
(1997)
Gene Ther
, vol.4
, pp. 577-585
-
-
Vrionis, F.D.1
Wu, J.K.2
Qi, P.3
Waltzman, M.4
Cherington, V.5
Spray, D.C.6
-
83
-
-
0032440742
-
The bystander effect in the HSVtk/ganciclovir system and its relationship to gap junctional communication
-
Touraine RL, Ishii-Morita H, Ramsey WJ, Blaese RM. The bystander effect in the HSVtk/ganciclovir system and its relationship to gap junctional communication. Gene Ther 1998; 5:1705-1711.
-
(1998)
Gene Ther
, vol.5
, pp. 1705-1711
-
-
Touraine, R.L.1
Ishii-Morita, H.2
Ramsey, W.J.3
Blaese, R.M.4
-
84
-
-
0034035078
-
Selective inhibition of hepatoma cells using diphtheria toxin A under the control of the promoter/enhancer region of the human alpha- fetoprotein gene
-
Kunitomi M, Takayama E, Suzuki S, Yasuda T, Tsutsui K, Nagaike K, Hiroi S, Tadakuma T. Selective inhibition of hepatoma cells using diphtheria toxin A under the control of the promoter/enhancer region of the human alpha- fetoprotein gene. Jpn J Cancer Res 2000; 91:343-350.
-
(2000)
Jpn J Cancer Res
, vol.91
, pp. 343-350
-
-
Kunitomi, M.1
Takayama, E.2
Suzuki, S.3
Yasuda, T.4
Tsutsui, K.5
Nagaike, K.6
Hiroi, S.7
Tadakuma, T.8
-
85
-
-
0034186199
-
Gene delivery with optimized electroporation parameters shows potential for treatment of gliomas
-
Yoshizato K, Nishi T, Goto T, Dev SB, Takeshima H, Kino T, Tada K, Kimura T, Shiraishi S, Kochi M, Kuratsu JI, Hofmann GA, Ushio Y. Gene delivery with optimized electroporation parameters shows potential for treatment of gliomas. Int J Oncol 2000; 16:899-905.
-
(2000)
Int J Oncol
, vol.16
, pp. 899-905
-
-
Yoshizato, K.1
Nishi, T.2
Goto, T.3
Dev, S.B.4
Takeshima, H.5
Kino, T.6
Tada, K.7
Kimura, T.8
Shiraishi, S.9
Kochi, M.10
Kuratsu, J.I.11
Hofmann, G.A.12
Ushio, Y.13
-
86
-
-
0033050462
-
Cell-specific expression of the diphtheria toxin A-chain coding sequence under the control of the upstream region of the human alpha- fetoprotein gene
-
Murayama Y, Tadakuma T, Kunitomi M, Kumai K, Tsutsui K, Yasuda T, Kitajima M. Cell-specific expression of the diphtheria toxin A-chain coding sequence under the control of the upstream region of the human alpha- fetoprotein gene. J Surg Oncol 1999; 70:145-149.
-
(1999)
J Surg Oncol
, vol.70
, pp. 145-149
-
-
Murayama, Y.1
Tadakuma, T.2
Kunitomi, M.3
Kumai, K.4
Tsutsui, K.5
Yasuda, T.6
Kitajima, M.7
-
87
-
-
0032901285
-
Cytochrome P450-based cancer gene therapy: Recent advances and future prospects
-
Waxman DJ, Chen L, Hecht JE, Jounaidi Y. Cytochrome P450-based cancer gene therapy: recent advances and future prospects. Drug Metab Rev 1999; 31:503-522.
-
(1999)
Drug Metab Rev
, vol.31
, pp. 503-522
-
-
Waxman, D.J.1
Chen, L.2
Hecht, J.E.3
Jounaidi, Y.4
-
88
-
-
0034153542
-
Pro-apoptotic treatment with an adenovirus encoding Bax enhances the effect of chemotherapy in ovarian cancer
-
Xiang J, Gomez-Navarro J, Arafat W, Liu B, Barker SD, Alvarez RD, Siegal GP, Curiel DT. Pro-apoptotic treatment with an adenovirus encoding Bax enhances the effect of chemotherapy in ovarian cancer. J Gene Med 2000; 2:97-106.
-
(2000)
J Gene Med
, vol.2
, pp. 97-106
-
-
Xiang, J.1
Gomez-Navarro, J.2
Arafat, W.3
Liu, B.4
Barker, S.D.5
Alvarez, R.D.6
Siegal, G.P.7
Curiel, D.T.8
-
89
-
-
0032725925
-
Gene therapy of genetic diseases and cancer
-
Mclvor RS. Gene therapy of genetic diseases and cancer. Pediatric Transplantation 1999; 3:116-121.
-
(1999)
Pediatric Transplantation
, vol.3
, pp. 116-121
-
-
McLvor, R.S.1
-
90
-
-
0034152996
-
Hypothesis: Naked plasmid DNA is taken up by cells in vivo by a receptor-mediated process
-
Budker V, Budker T, Zhang G, Subbotin V, Loomis A, Wolff JA. Hypothesis: naked plasmid DNA is taken up by cells in vivo by a receptor-mediated process. J Gene Med 2000; 2:76-88.
-
(2000)
J Gene Med
, vol.2
, pp. 76-88
-
-
Budker, V.1
Budker, T.2
Zhang, G.3
Subbotin, V.4
Loomis, A.5
Wolff, J.A.6
-
91
-
-
0004052035
-
Immune pathways used in nucleic acid vaccination
-
Huang L, Hung MC, Wagner E, eds., San Diego: Academic Press
-
Rhodes GH. Immune pathways used in nucleic acid vaccination. In: Huang L, Hung MC, Wagner E, eds. Nonviral Vectors for Gene Therapy. San Diego: Academic Press, 1999, pp 379-408.
-
(1999)
Nonviral Vectors for Gene Therapy
, pp. 379-408
-
-
Rhodes, G.H.1
-
92
-
-
0028060149
-
Intradermal gene immunization: The possible role of DNA uptake in the induction of cellular immunity to viruses
-
Raz E, Carson DA, Parker SE, Parr TB, Abai AM, Aichinger G, Gromkowski SH, Singh M, Lew D, Yankauckas MA, et al. Intradermal gene immunization: the possible role of DNA uptake in the induction of cellular immunity to viruses. Proc Natl Acad Sci USA 1994; 91:9519-9523.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 9519-9523
-
-
Raz, E.1
Carson, D.A.2
Parker, S.E.3
Parr, T.B.4
Abai, A.M.5
Aichinger, G.6
Gromkowski, S.H.7
Singh, M.8
Lew, D.9
Yankauckas, M.A.10
-
93
-
-
0032879349
-
Immunization via hair follicles by topical application of naked DNA to normal skin
-
Fan H, Lin Q, Morrissey GR, Khavari PA. Immunization via hair follicles by topical application of naked DNA to normal skin. Nat Biotechnol 1999; 17:870-872.
-
(1999)
Nat Biotechnol
, vol.17
, pp. 870-872
-
-
Fan, H.1
Lin, Q.2
Morrissey, G.R.3
Khavari, P.A.4
-
94
-
-
0032805251
-
Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA
-
Liu F, Song Y, Liu D. Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA. Gene Ther 1999; 6:1258-1266.
-
(1999)
Gene Ther
, vol.6
, pp. 1258-1266
-
-
Liu, F.1
Song, Y.2
Liu, D.3
-
95
-
-
0036173196
-
Systemic administration of naked DNA encoding interleukin 12 for the treatment of human papillomavirus DNA-positive tumor
-
Lui VW, He Y, Falo L, Huang L. Systemic administration of naked DNA encoding interleukin 12 for the treatment of human papillomavirus DNA-positive tumor. Hum Gene Ther 2002; 13(2):177-185.
-
(2002)
Hum Gene Ther
, vol.13
, Issue.2
, pp. 177-185
-
-
Lui, V.W.1
He, Y.2
Falo, L.3
Huang, L.4
-
96
-
-
0035407547
-
Systemic production of IL-12 by naked DNA mediated gene transfer-toxicity and attenuation of transgene expression in vivo
-
Lui VW, Falo LD Jr, Huang L. Systemic production of IL-12 by naked DNA mediated gene transfer-toxicity and attenuation of transgene expression in vivo. J Gene Med 2001; 3(4):384-393.
-
(2001)
J Gene Med
, vol.3
, Issue.4
, pp. 384-393
-
-
Lui, V.W.1
Falo, L.D.2
Huang, L.3
-
97
-
-
0035524128
-
Improving plasmid DNA-mediated liver gene transfer by prolonging its retention in the hepatic vasculature
-
Liu F, Huang L. Improving plasmid DNA-mediated liver gene transfer by prolonging its retention in the hepatic vasculature. J Gene Med 2001; 3(6):569-576.
-
(2001)
J Gene Med
, vol.3
, Issue.6
, pp. 569-576
-
-
Liu, F.1
Huang, L.2
-
98
-
-
0030709447
-
Expression of naked plasmid DNA injected into the afferent and efferent vessels of rodent and dog livers
-
Zhang G, Vargo D, Budker V, Armstrong N, Knechtle S, Wolff JA. Expression of naked plasmid DNA injected into the afferent and efferent vessels of rodent and dog livers. Hum Gene Ther 1997; 8:1763-1772.
-
(1997)
Hum Gene Ther
, vol.8
, pp. 1763-1772
-
-
Zhang, G.1
Vargo, D.2
Budker, V.3
Armstrong, N.4
Knechtle, S.5
Wolff, J.A.6
-
99
-
-
0031935395
-
The efficient expression of intravascularly delivered DNA in rat muscle
-
Budker V, Zhang G, Danko I, Williams P, Wolff J. The efficient expression of intravascularly delivered DNA in rat muscle. Gene Ther 1998; 5:272-276.
-
(1998)
Gene Ther
, vol.5
, pp. 272-276
-
-
Budker, V.1
Zhang, G.2
Danko, I.3
Williams, P.4
Wolff, J.5
-
100
-
-
17344364349
-
Antitumor activity of bax and p53 naked gene transfer in lung cancer: In vitro and in vivo analysis
-
Coll JL, Negoescu A, Louis N, Sachs L, Tenaud C, Girardot V, Demeinex B, Brambilla E, Brambilla C, Favrot M. Antitumor activity of bax and p53 naked gene transfer in lung cancer: in vitro and in vivo analysis. Hum Gene Ther 1998; 9: 2063-2074.
-
(1998)
Hum Gene Ther
, vol.9
, pp. 2063-2074
-
-
Coll, J.L.1
Negoescu, A.2
Louis, N.3
Sachs, L.4
Tenaud, C.5
Girardot, V.6
Demeinex, B.7
Brambilla, E.8
Brambilla, C.9
Favrot, M.10
-
101
-
-
0027142891
-
Electrochemotheraphy, a new antitumor treatment. First clinical phase I-II trial
-
Belehradek M, Domenge C, Luboinski B, Orlowski S, Belehradek J Jr, Mir LM. Electrochemotheraphy, a new antitumor treatment. First clinical phase I-II trial. Cancer 1993; 72:3694-3700.
-
(1993)
Cancer
, vol.72
, pp. 3694-3700
-
-
Belehradek, M.1
Domenge, C.2
Luboinski, B.3
Orlowski, S.4
Belehradek, J.5
Mir, L.M.6
-
102
-
-
12944273467
-
Highly efficient electro-gene therapy of solid tumor by using an expression plasmid for the herpes simplex virus thymidine kinase gene
-
Goto T, Nishi T, Tamura T, Dev SB, Takeshima H, Kochi M, Yoshizato K, Kuratsu J, Sakata T, Hofmann GA, Ushio Y. Highly efficient electro-gene therapy of solid tumor by using an expression plasmid for the herpes simplex virus thymidine kinase gene. Proc Natl Acad Sci USA 2000; 97:354-359.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 354-359
-
-
Goto, T.1
Nishi, T.2
Tamura, T.3
Dev, S.B.4
Takeshima, H.5
Kochi, M.6
Yoshizato, K.7
Kuratsu, J.8
Sakata, T.9
Hofmann, G.A.10
Ushio, Y.11
-
103
-
-
0025600919
-
In vivo and in vitro gene transfer to mammalian somatic cells by particel bombardment
-
Yang N-S, Burkholder J, Roberts B, Martinell B, McCabe D. In vivo and in vitro gene transfer to mammalian somatic cells by particel bombardment. PNAS 1990; 87:9568-9572.
-
(1990)
PNAS
, vol.87
, pp. 9568-9572
-
-
Yang, N.-S.1
Burkholder, J.2
Roberts, B.3
Martinell, B.4
McCabe, D.5
-
104
-
-
9844239373
-
Interferon-alpha gene therapy for cancer: Retroviral transduction of fibroblasts and particle-mediated transfection of tumor cells are both effective strategies for gene delivery in murine tumor models
-
Tuting T, Gambotto A, Baar J, Davis ID Storkus WJ, Zavodny PJ, Narula S, Tahara H, Robbins PD, Lotze MT. Interferon-alpha gene therapy for cancer: retroviral transduction of fibroblasts and particle-mediated transfection of tumor cells are both effective strategies for gene delivery in murine tumor models. Gene Ther 1997; 4: 1053-1060.
-
(1997)
Gene Ther
, vol.4
, pp. 1053-1060
-
-
Tuting, T.1
Gambotto, A.2
Baar, J.3
Davis Id Storkus, W.J.4
Zavodny, P.J.5
Narula, S.6
Tahara, H.7
Robbins, P.D.8
Lotze, M.T.9
-
105
-
-
0030138921
-
Dual expression of human leukocyte antigen molecules and the B7-1 costimulatory molecule (CD80) on human melanoma cells after particle mediated gene transfer
-
Albertini MR, Emler CA, Schell K, Tans KJ, King DM, Sheehy MJ. Dual expression of human leukocyte antigen molecules and the B7-1 costimulatory molecule (CD80) on human melanoma cells after particle mediated gene transfer. Cancer Gene Ther 1996; 3:192-201.
-
(1996)
Cancer Gene Ther
, vol.3
, pp. 192-201
-
-
Albertini, M.R.1
Emler, C.A.2
Schell, K.3
Tans, K.J.4
King, D.M.5
Sheehy, M.J.6
-
106
-
-
0032603733
-
Preclinical development of human granulocyte-macrophage colony-stimulating factor-transfected melanoma cell vaccine using established canine cell lines and normal dogs
-
Hogge GS, Burkholder JK, Culp J, Albertini MR, Dubielzig RR, Yang NS, MacEwen EG. Preclinical development of human granulocyte-macrophage colony-stimulating factor-transfected melanoma cell vaccine using established canine cell lines and normal dogs. Cancer Gene Ther 1999; 6:26-36.
-
(1999)
Cancer Gene Ther
, vol.6
, pp. 26-36
-
-
Hogge, G.S.1
Burkholder, J.K.2
Culp, J.3
Albertini, M.R.4
Dubielzig, R.R.5
Yang, N.S.6
Macewen, E.G.7
-
107
-
-
0032170665
-
Development of human granulocyte-macrophage colony-stimulating factor-transfected tumor cell vaccines for the treatment of spontaneous canine cancer
-
Hogge GS, Burkholder JK, Culp J, Albertini MR, Dubielzig RR, Keller ET, Yang NS, MacEwen EG. Development of human granulocyte-macrophage colony-stimulating factor-transfected tumor cell vaccines for the treatment of spontaneous canine cancer. Hum Gene Ther 1998; 9:1851-1861.
-
(1998)
Hum Gene Ther
, vol.9
, pp. 1851-1861
-
-
Hogge, G.S.1
Burkholder, J.K.2
Culp, J.3
Albertini, M.R.4
Dubielzig, R.R.5
Keller, E.T.6
Yang, N.S.7
Macewen, E.G.8
-
108
-
-
0029947820
-
Gene gun-mediated skin transfection with interleukin 12 gene results in regression of established primary and metastatic murine tumors
-
Rakhmilevich AL, Turner J, Ford MJ, McCabe D, Sun WH, Sondel PM, Grota K, Yang NS. Gene gun-mediated skin transfection with interleukin 12 gene results in regression of established primary and metastatic murine tumors. Proc Natl Acad Sci USA 1996; 93:6291-6296.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 6291-6296
-
-
Rakhmilevich, A.L.1
Turner, J.2
Ford, M.J.3
McCabe, D.4
Sun, W.H.5
Sondel, P.M.6
Grota, K.7
Yang, N.S.8
-
109
-
-
0032922137
-
In vivo gene therapy with interleukin-12 inhibits primary vascular tumor growth and induces apoptosis in a mouse model
-
Wang C, Quevedo ME, Lannutti BJ, Gordon KB, Guo D, Sun W, Paller AS. In vivo gene therapy with interleukin-12 inhibits primary vascular tumor growth and induces apoptosis in a mouse model. J Invest Dermatol 1999; 112:775-781.
-
(1999)
J Invest Dermatol
, vol.112
, pp. 775-781
-
-
Wang, C.1
Quevedo, M.E.2
Lannutti, B.J.3
Gordon, K.B.4
Guo, D.5
Sun, W.6
Paller, A.S.7
-
110
-
-
0033399436
-
Particle-mediated gene transfer of murine interleukin-12 cDNA suppresses the growth of Lewis lung carcinoma
-
Oshikawa K, Ishii Y, Hamamoto T, Sugiyama Y, Kitamura S, Kagawa Y. Particle-mediated gene transfer of murine interleukin-12 cDNA suppresses the growth of Lewis lung carcinoma. In Vivo 1999; 13:397-402.
-
(1999)
In Vivo
, vol.13
, pp. 397-402
-
-
Oshikawa, K.1
Ishii, Y.2
Hamamoto, T.3
Sugiyama, Y.4
Kitamura, S.5
Kagawa, Y.6
-
111
-
-
0028940375
-
In vivo cytokine gene transfer by gene gun reduces tumor growth in mice
-
Sun WH, Burkholder JK, Sun J, Culp J, Turner J, Lu XG, Pugh TD, Ershler WB, Yang NS. In vivo cytokine gene transfer by gene gun reduces tumor growth in mice. Proc Natl Acad Sci USA 1995; 92:2889-2893.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 2889-2893
-
-
Sun, W.H.1
Burkholder, J.K.2
Sun, J.3
Culp, J.4
Turner, J.5
Lu, X.G.6
Pugh, T.D.7
Ershler, W.B.8
Yang, N.S.9
-
112
-
-
0028913411
-
Liposome-mediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis
-
[see comments] published erratum appears in Nat Med 1995 Mar; 1(3):272]
-
Caplen NJ, Alton EW, Middleton PG, Dorin JR, Stevenson BJ, Gao X, Durham SR, Jeffery PK, Hodson ME, Coutelle C, et al. Liposome-mediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis [see comments] published erratum appears in Nat Med 1995 Mar; 1(3):272]. Nat Med 1995; 1:39-46.
-
(1995)
Nat Med
, vol.1
, pp. 39-46
-
-
Caplen, N.J.1
Alton, E.W.2
Middleton, P.G.3
Dorin, J.R.4
Stevenson, B.J.5
Gao, X.6
Durham, S.R.7
Jeffery, P.K.8
Hodson, M.E.9
Coutelle, C.10
-
113
-
-
0027517321
-
Direct gene transfer with DNA-liposome complexes in melanoma: Expression, biologic activity, and lack of toxicity in humans
-
Nabel GJ, Nabel E, Yang ZY, Fox BA, Plautz G, Gao X, Huang L, Shu S, Gordon D, Chang AE. Direct gene transfer with DNA-liposome complexes in melanoma: Expression, biologic activity, and lack of toxicity in humans. PNAS 1993; 90: 11307-11311.
-
(1993)
PNAS
, vol.90
, pp. 11307-11311
-
-
Nabel, G.J.1
Nabel, E.2
Yang, Z.Y.3
Fox, B.A.4
Plautz, G.5
Gao, X.6
Huang, L.7
Shu, S.8
Gordon, D.9
Chang, A.E.10
-
114
-
-
0030845845
-
Phase I study of immunotheraphy of cutaneous metastases of human carcinoma using allogeneic and xenogeneic MHC-DNA-liposome complexes
-
Hui KM, Ang PT, Huang L, Tay SK. Phase I study of immunotheraphy of cutaneous metastases of human carcinoma using allogeneic and xenogeneic MHC-DNA-liposome complexes. Gene Ther 1997; 4:783-790.
-
(1997)
Gene Ther
, vol.4
, pp. 783-790
-
-
Hui, K.M.1
Ang, P.T.2
Huang, L.3
Tay, S.K.4
-
115
-
-
0031446338
-
In vivo delivery to the liver using reconstituted chylomicron remnants as a novel non-viral vector
-
Hara T, Tan Y, Huang L. In vivo delivery to the liver using reconstituted chylomicron remnants as a novel non-viral vector. PNAS 1997; 94:14547-14552.
-
(1997)
PNAS
, vol.94
, pp. 14547-14552
-
-
Hara, T.1
Tan, Y.2
Huang, L.3
-
116
-
-
0032475867
-
Proteoglycans mediated cationic liposome-DNA complex-based gene delivery in vitro and in vivo
-
Mounkes LC, Zhong W, Cipres-Palacin G, Heath TD, Debs RJ. Proteoglycans mediated cationic liposome-DNA complex-based gene delivery in vitro and in vivo. J Biol Chem 1998; 273:26164-26170.
-
(1998)
J Biol Chem
, vol.273
, pp. 26164-26170
-
-
Mounkes, L.C.1
Zhong, W.2
Cipres-Palacin, G.3
Heath, T.D.4
Debs, R.J.5
-
117
-
-
0029981092
-
Evidence for the role of proteoglycans in cationmediated gene transfer
-
Mislick KA, Baldeschwieler JD. Evidence for the role of proteoglycans in cationmediated gene transfer. PNAS 1996; 93:12349-12354.
-
(1996)
PNAS
, vol.93
, pp. 12349-12354
-
-
Mislick, K.A.1
Baldeschwieler, J.D.2
-
118
-
-
0031851486
-
Characterization of cationic lipid prota-mine-DNA (LPD) complexes for intravenous gene delivery
-
Li S, Rizzo MA, Bhattacharya S, Huang L. Characterization of cationic lipid prota-mine-DNA (LPD) complexes for intravenous gene delivery. Gene Ther 1998; 5: 930-937.
-
(1998)
Gene Ther
, vol.5
, pp. 930-937
-
-
Li, S.1
Rizzo, M.A.2
Bhattacharya, S.3
Huang, L.4
-
119
-
-
0029949266
-
Mechanism of DNA release from cationic liposome/DNA complexes used in cell transfection
-
Xu Y, Szoka FC. Mechanism of DNA release from cationic liposome/DNA complexes used in cell transfection. Biochemistry 1996; 35:5616-5623.
-
(1996)
Biochemistry
, vol.35
, pp. 5616-5623
-
-
Xu, Y.1
Szoka, F.C.2
-
120
-
-
0031974554
-
DNA vector chemistry: The covalent attachment of signal peptides to plasmid DNA
-
Sebestyen MG, Ludtke JJ, Bassik MC, Zhang G, Budker V, Lukhtanov EA, Hagstrom JE, Wolff JA. DNA vector chemistry: the covalent attachment of signal peptides to plasmid DNA. Nat Biotechnol 1998; 16:80-85.
-
(1998)
Nat Biotechnol
, vol.16
, pp. 80-85
-
-
Sebestyen, M.G.1
Ludtke, J.J.2
Bassik, M.C.3
Zhang, G.4
Budker, V.5
Lukhtanov, E.A.6
Hagstrom, J.E.7
Wolff, J.A.8
-
121
-
-
0034059514
-
Cell cycle dependence of gene transfer by lipoplex, polyplex and recombinant adenovirus
-
Brunner S, Sauer T, Carotta S, Cotten M, Saltik M, Wagner E. Cell cycle dependence of gene transfer by lipoplex, polyplex and recombinant adenovirus. Gene Ther 2000; 7:401-407.
-
(2000)
Gene Ther
, vol.7
, pp. 401-407
-
-
Brunner, S.1
Sauer, T.2
Carotta, S.3
Cotten, M.4
Saltik, M.5
Wagner, E.6
-
122
-
-
0032991780
-
A novel T7 RNA polymerase autogene for efficient cytoplasmic expression of target genes
-
Brisson M, He Y, Li S, Yang JP, Huang L. A novel T7 RNA polymerase autogene for efficient cytoplasmic expression of target genes. Gene Therapy 1999; 6:263-270.
-
(1999)
Gene Therapy
, vol.6
, pp. 263-270
-
-
Brisson, M.1
He, Y.2
Li, S.3
Yang, J.P.4
Huang, L.5
-
123
-
-
0027290777
-
Cytoplasmic expression of a reporter gene by co-delivery of T7 RNA polymerase and T7 promoter sequence with cationic liposomesc
-
Gao X, Huang L. Cytoplasmic expression of a reporter gene by co-delivery of T7 RNA polymerase and T7 promoter sequence with cationic liposomesc. Nucleic Acids Res 1993; 21:2867-2872.
-
(1993)
Nucleic Acids Res
, vol.21
, pp. 2867-2872
-
-
Gao, X.1
Huang, L.2
-
124
-
-
0032125910
-
Synthesis of novel polyampholyte comb-type copolymers consisting of a poly(L-lysine) backbone and hyaluronic acid side chains for a DNA carrier
-
Asayama S, Nogawa M, Takei Y, Akaike T, Maruyama A. Synthesis of novel polyampholyte comb-type copolymers consisting of a poly(L-lysine) backbone and hyaluronic acid side chains for a DNA carrier. Bioconjug Chem 1998; 9:476-481.
-
(1998)
Bioconjug Chem
, vol.9
, pp. 476-481
-
-
Asayama, S.1
Nogawa, M.2
Takei, Y.3
Akaike, T.4
Maruyama, A.5
-
125
-
-
0033972869
-
Nonviral gene therapy: Promises and challenges
-
Li S, Huang L. Nonviral gene therapy: promises and challenges. Gene Ther 2000; 7:31-34.
-
(2000)
Gene Ther
, vol.7
, pp. 31-34
-
-
Li, S.1
Huang, L.2
-
126
-
-
0000207484
-
Polyethylenimines: A family of potent polymers for nucleic acid delivery
-
Huang L, Hung MC, Wagner E, eds., San Diego: Academic Press
-
Kichler A, Behr J-P, Erbacher P. Polyethylenimines: a family of potent polymers for nucleic acid delivery. In: Huang L, Hung MC, Wagner E, eds. Nonviral Vectors for Gene Therapy. San Diego: Academic Press, 1999; pp 191-206.
-
(1999)
Nonviral Vectors for Gene Therapy
, pp. 191-206
-
-
Kichler, A.1
Behr, J.-P.2
Erbacher, P.3
-
127
-
-
0003008343
-
Synthetic DNA delivery systems
-
Luo D, Saltzman WM. Synthetic DNA delivery systems. Nat Biotechnol 2000; 18: 33-37.
-
(2000)
Nat Biotechnol
, vol.18
, pp. 33-37
-
-
Luo, D.1
Saltzman, W.M.2
-
128
-
-
0005867445
-
Biopolymer-DNA nanospheres
-
Huang L, Hung MC, Wagner E, eds., San Diego: Academic Press
-
Leong KW. Biopolymer-DNA nanospheres. In: Huang L, Hung MC, Wagner E, eds. Nonviral Vectors for Gene Therapy. San Diego: Academic Press, 1999, pp 267-287.
-
(1999)
Nonviral Vectors for Gene Therapy
, pp. 267-287
-
-
Leong, K.W.1
-
129
-
-
0038004448
-
A novel non-viral vector for DNA delivery based on low molecular weight, branched polyethylenimine: Effect of molecular weight on transfection efficiency and cytotoxicity
-
Fischer D, Bieber T, Li Y, Elsasser HP, Kissel T. A novel non-viral vector for DNA delivery based on low molecular weight, branched polyethylenimine: effect of molecular weight on transfection efficiency and cytotoxicity. Pharm Res 1999; 16:1273-1279.
-
(1999)
Pharm Res
, vol.16
, pp. 1273-1279
-
-
Fischer, D.1
Bieber, T.2
Li, Y.3
Elsasser, H.P.4
Kissel, T.5
-
130
-
-
0000942981
-
Ligand-polycation conjugates for receptor-targeted gene transfer
-
Huang L, Hung MC, Wagner E, eds., San Diego: Academic Press
-
Wagner E. Ligand-polycation conjugates for receptor-targeted gene transfer. In: Huang L, Hung MC, Wagner E, eds. Nonviral Vectors for Gene Therapy. San Diego: Academic Press, 1999, pp 207-227.
-
(1999)
Nonviral Vectors for Gene Therapy
, pp. 207-227
-
-
Wagner, E.1
-
131
-
-
0033084717
-
Complexes for tumor-targeted gene delivery in vivo
-
Kircheis R, Schuller S, Brunner S, Ogris M, Heider KH, Zauner W, Wagner E. Polycation-based DNA complexes for tumor-targeted gene delivery in vivo. J Gene Med 1999; 1:111-120.
-
(1999)
J Gene Med
, vol.1
, pp. 111-120
-
-
Kircheis, R.1
Schuller, S.2
Brunner, S.3
Ogris, M.4
Heider, K.H.5
Zauner, W.6
Wagner, E.7
Polycation-Based, D.8
-
133
-
-
0031953510
-
Intercellular delivery of functional p53 by the herpesvirus protein VP22
-
Phelan A, Elliott G, O’Hare P. Intercellular delivery of functional p53 by the herpesvirus protein VP22. Nat Biotechnol 1998; 16:440-443.
-
(1998)
Nat Biotechnol
, vol.16
, pp. 440-443
-
-
Phelan, A.1
Elliott, G.2
O’Hare, P.3
-
134
-
-
0033962107
-
Cytoplasm-to-nucleus translocation of a herpesvirus tegument protein during cell division
-
Elliott G, O’Hare P. Cytoplasm-to-nucleus translocation of a herpesvirus tegument protein during cell division. J Virol 2000; 74:2131-2141.
-
(2000)
J Virol
, vol.74
, pp. 2131-2141
-
-
Elliott, G.1
O’Hare, P.2
-
135
-
-
0032896455
-
Intercellular delivery of thymidine kinase prodrug activating enzyme by the herpes simplex virus protein, VP22
-
Dilber MS, Phelan A, Aints A, Mohamed AJ, Elliott G, Smith CI, O’Hare P. Intercellular delivery of thymidine kinase prodrug activating enzyme by the herpes simplex virus protein, VP22. Gene Ther 1999; 6:12-21.
-
(1999)
Gene Ther
, vol.6
, pp. 12-21
-
-
Dilber, M.S.1
Phelan, A.2
Aints, A.3
Mohamed, A.J.4
Elliott, G.5
Smith, C.I.6
O’Hare, P.7
-
136
-
-
0034103009
-
Somatic integration and long-term transgene expression in normal and haemophilic mice using a DNA transposon system
-
Yant SR, Meuse L, Chiu W, Ivics Z, Izsvak Z, Kay MA. Somatic integration and long-term transgene expression in normal and haemophilic mice using a DNA transposon system. Nat Genet 2000; 25:35-41.
-
(2000)
Nat Genet
, vol.25
, pp. 35-41
-
-
Yant, S.R.1
Meuse, L.2
Chiu, W.3
Ivics, Z.4
Izsvak, Z.5
Kay, M.A.6
-
137
-
-
0034029495
-
Increasing endothelial cell specific expression by the use of heterologous hypoxic and cytokine-inducible enhancers
-
Modlich U, Pugh CW, Bicknell R. Increasing endothelial cell specific expression by the use of heterologous hypoxic and cytokine-inducible enhancers. Gene Ther 2000; 7:896-902.
-
(2000)
Gene Ther
, vol.7
, pp. 896-902
-
-
Modlich, U.1
Pugh, C.W.2
Bicknell, R.3
-
138
-
-
0034175969
-
Gene therapy: Designer promoters for tumour targeting
-
Nettelbeck DM, Jerome V, Muller R. Gene therapy: designer promoters for tumour targeting. Trends Genet 2000; 16:174-181.
-
(2000)
Trends Genet
, vol.16
, pp. 174-181
-
-
Nettelbeck, D.M.1
Jerome, V.2
Muller, R.3
-
139
-
-
0033946373
-
Breast cancer-specific expression of the Candida albicans cytosine deaminase gene using a transcriptional targeting approach
-
Anderson LM, Krotz S, Weitzman SA, Thimmapaya B. Breast cancer-specific expression of the Candida albicans cytosine deaminase gene using a transcriptional targeting approach. Cancer Gene Ther 2000; 7:845-852.
-
(2000)
Cancer Gene Ther
, vol.7
, pp. 845-852
-
-
Anderson, L.M.1
Krotz, S.2
Weitzman, S.A.3
Thimmapaya, B.4
-
140
-
-
0034168328
-
Osteocalcin-directed gene therapy for prostate-cancer bone metastasis
-
Koeneman KS, Kao C, Ko SC, Yang L, Wada Y, Kallmes DF, Gillenwater JY, Zhau HE, Chung LW, Gardner TA. Osteocalcin-directed gene therapy for prostate-cancer bone metastasis. World J Urol 2000; 18:102-110.
-
(2000)
World J Urol
, vol.18
, pp. 102-110
-
-
Koeneman, K.S.1
Kao, C.2
Ko, S.C.3
Yang, L.4
Wada, Y.5
Kallmes, D.F.6
Gillenwater, J.Y.7
Zhau, H.E.8
Chung, L.W.9
Gardner, T.A.10
-
141
-
-
0034685453
-
Transactivation of the metallothionein promoter in cisplatin-resistant cancer cells: A specific gene therapy strategy
-
Vandier D, Calvez V, Massade L, Gouyette A, Mickley L, Fojo T, Rixe O. Transactivation of the metallothionein promoter in cisplatin-resistant cancer cells: a specific gene therapy strategy. J Natl Cancer Inst 2000; 92:642-647.
-
(2000)
J Natl Cancer Inst
, vol.92
, pp. 642-647
-
-
Vandier, D.1
Calvez, V.2
Massade, L.3
Gouyette, A.4
Mickley, L.5
Fojo, T.6
Rixe, O.7
-
142
-
-
0034029495
-
Increasing endothelial cell specific expression by the use of heterologous hypoxic and cytokine-inducible enhancers
-
Modlich U, Pugh CW, Bicknell R. Increasing endothelial cell specific expression by the use of heterologous hypoxic and cytokine-inducible enhancers. Gene Ther 2000; 7:896-902.
-
(2000)
Gene Ther
, vol.7
, pp. 896-902
-
-
Modlich, U.1
Pugh, C.W.2
Bicknell, R.3
-
143
-
-
0034163475
-
Strength and specificity of different gene promoters in oral cancer cells
-
Shillitoe EJ, Noonan S. Strength and specificity of different gene promoters in oral cancer cells. Oral Oncol 2000; 36:214-220.
-
(2000)
Oral Oncol
, vol.36
, pp. 214-220
-
-
Shillitoe, E.J.1
Noonan, S.2
-
144
-
-
0034235413
-
A novel telomerase-specific gene therapy: Gene transfer of caspase-8 utilizing the human telomerase catalytic subunit gene promoter
-
Koga S, Hirohata S, Kondo Y, Komata T, Takakura M, Inoue M, Kyo S, Kondo S. A novel telomerase-specific gene therapy: gene transfer of caspase-8 utilizing the human telomerase catalytic subunit gene promoter. Hum Gene Ther 2000; 11: 1397-1406.
-
(2000)
Hum Gene Ther
, vol.11
, pp. 1397-1406
-
-
Koga, S.1
Hirohata, S.2
Kondo, Y.3
Komata, T.4
Takakura, M.5
Inoue, M.6
Kyo, S.7
Kondo, S.8
-
145
-
-
0034123875
-
Cancer gene therapy by thyroid hormone-mediated expression of toxin genes
-
Martin V, Cortes ML, de Felipe P, Farsetti A, Calcaterra NB, Izquierdo M. Cancer gene therapy by thyroid hormone-mediated expression of toxin genes. Cancer Res 2000; 60:3218-3224.
-
(2000)
Cancer Res
, vol.60
, pp. 3218-3224
-
-
Martin, V.1
Cortes, M.L.2
De Felipe, P.3
Farsetti, A.4
Calcaterra, N.B.5
Izquierdo, M.6
-
146
-
-
0034100789
-
Eradication of murine mammary adenocarcinoma through HSVtk expression directed by the glucose-starvation inducible grp78 promoter
-
Chen X, Zhang D, Dennert G, Hung G, Lee AS. Eradication of murine mammary adenocarcinoma through HSVtk expression directed by the glucose-starvation inducible grp78 promoter. Breast Cancer Res Treat 2000; 59:81-90.
-
(2000)
Breast Cancer Res Treat
, vol.59
, pp. 81-90
-
-
Chen, X.1
Zhang, D.2
Dennert, G.3
Hung, G.4
Lee, A.S.5
-
147
-
-
0010276632
-
Lipid-DNA complexes induce potent activation of innate immune responses and antitumor activity when administered intravenously
-
Dow SW, Fradkin LG, Liggitt DH, Willson AP, Heath TD, Potter TA. Lipid-DNA complexes induce potent activation of innate immune responses and antitumor activity when administered intravenously. J Immunol 1999; 163:1552-1561.
-
(1999)
J Immunol
, vol.163
, pp. 1552-1561
-
-
Dow, S.W.1
Fradkin, L.G.2
Liggitt, D.H.3
Willson, A.P.4
Heath, T.D.5
Potter, T.A.6
-
148
-
-
0033585425
-
Contribution of plasmid DNA to inflammation in the lung after administration of cationic lipid:PDNA complexes
-
Yew NS, Wang KX, Przybylska M, Bagley RG, Stedman M, Marshall J, Scheule RK, Cheng SH. Contribution of plasmid DNA to inflammation in the lung after administration of cationic lipid:pDNA complexes. Hum Gene Ther 1999; 10:223-234.
-
(1999)
Hum Gene Ther
, vol.10
, pp. 223-234
-
-
Yew, N.S.1
Wang, K.X.2
Przybylska, M.3
Bagley, R.G.4
Stedman, M.5
Marshall, J.6
Scheule, R.K.7
Cheng, S.H.8
-
149
-
-
0032732516
-
LPD lipopolyplex initiates a potent cytokine response and inhibits tumor growth
-
Whitmore M, Li S, Huang L. LPD lipopolyplex initiates a potent cytokine response and inhibits tumor growth. Gene Ther 1999; 6:1867-1875.
-
(1999)
Gene Ther
, vol.6
, pp. 1867-1875
-
-
Whitmore, M.1
Li, S.2
Huang, L.3
-
150
-
-
0032599950
-
Direct immunologic activities of CpG DNA and implications for gene therapy
-
Krieg AM. Direct immunologic activities of CpG DNA and implications for gene therapy. J Gene Med 1999; 1:56-63.
-
(1999)
J Gene Med
, vol.1
, pp. 56-63
-
-
Krieg, A.M.1
-
151
-
-
0034073872
-
Immuno-stimulatory DNA-based vaccines induce cytotoxic lymphocyte activity by a T-helper cell-independent mechanism
-
Cho HJ, Takabayashi K, Cheng PM, Nguyen MD, Corr M, Tuck S, Raz E. Immuno-stimulatory DNA-based vaccines induce cytotoxic lymphocyte activity by a T-helper cell-independent mechanism. Nat Biotechnol 2000; 18:509-514.
-
(2000)
Nat Biotechnol
, vol.18
, pp. 509-514
-
-
Cho, H.J.1
Takabayashi, K.2
Cheng, P.M.3
Nguyen, M.D.4
Corr, M.5
Tuck, S.6
Raz, E.7
-
152
-
-
0034149827
-
Reduced inflammatory response to plasmid DNA vectors by elimination and inhibition of immunostimulatory CpG motifs
-
Yew NS, Zhao H, Wu I-H, Song A, Tousignant JD, Przybylska M, Cheng SH. Reduced inflammatory response to plasmid DNA vectors by elimination and inhibition of immunostimulatory CpG motifs. Molecular Therapy 2000; 1:1-8.
-
(2000)
Molecular Therapy
, vol.1
, pp. 1-8
-
-
Yew, N.S.1
Zhao, H.2
Wu, I.-H.3
Song, A.4
Tousignant, J.D.5
Przybylska, M.6
Cheng, S.H.7
-
153
-
-
0033199598
-
The inhibitory role of CpG immunostimulatory motifs in cationic lipid vector-mediated transgene expression in vivo [see comments]
-
Tan Y, Li S, Pitt BR, Huang L. The inhibitory role of CpG immunostimulatory motifs in cationic lipid vector-mediated transgene expression in vivo [see comments]. Hum Gene Ther 1999; 10:2153-2161.
-
(1999)
Hum Gene Ther
, vol.10
, pp. 2153-2161
-
-
Tan, Y.1
Li, S.2
Pitt, B.R.3
Huang, L.4
-
154
-
-
0033005285
-
Effect of immune response on gene transfer to the lung via systemic administration of cationic lipidic vectors
-
Li S, Wu SP, Whitmore M, Loeffert EJ, Wang L, Watkins SC, Pitt BR, Huang L. Effect of immune response on gene transfer to the lung via systemic administration of cationic lipidic vectors. Am J Physiol 1999; 276:L796-804
-
(1999)
Am J Physiol
, vol.276
, pp. L796-L804
-
-
Li, S.1
Wu, S.P.2
Whitmore, M.3
Loeffert, E.J.4
Wang, L.5
Watkins, S.C.6
Pitt, B.R.7
Huang, L.8
|