AAC-11 overexpression induces invasion and protects cervical cancer cells from apoptosis

Laboratory Investigation

Volumn 80, Issue 4, 2000, Pages 587-594

  Kim, Jin Woo ^a,b   Cho, Hyun Suk ^b   Kim, Jeong Hyun ^b   Hur, Soo Young ^a   Kim, Tae Eung ^a   Lee, Joon Mo ^a   Kim, In Kyung ^b   Namkoong, Sung Eun ^a  

^a The Catholic University of Korea   (South Korea)

^b The Catholic University of Korea   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; COLLAGENASE; GELATINASE A;

APOPTOSIS; ARTICLE; CANCER CELL; CANCER INVASION; CARCINOGENESIS; CONTROLLED STUDY; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE INDUCTION; GENE LOSS; GENE MUTATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; METASTASIS; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; UTERINE CERVIX CANCER;

EID: 0343294335     PISSN: 00236837     EISSN: None     Source Type: Journal    
DOI: 10.1038/labinvest.3780063     Document Type: Article

References (27)

1. Albini A, Iwamoto Y, Kleinman HK, Martin GR, Aarronson SA, Kozlowski JM, and McEwan RN (1987). A rapid in vitro assay for quantitating the invasive potential of tumor cells. Cancer Res 47:3239-3245.
2. Brooks PC, Stromblad S, Sanders LC, von Schalscha TL, Aimes RT, Stetler-Stevenson WG, Quigley JP, and Cheresh DA (1996). Localization of matrix metalloproteinase MMP-2 to the surface of invasive cells by interaction with integrin αvβ3. Cell 85:683-693.
3. Choo KB, Chong KY, Chou HF, Liew LN, and Liou CC (1989). Analysis of the structure and expression of the c-myc oncogene in cervical tumor and in cervical tumor-derived cell lines. Biochem Biophys Res Commun 158:334-340.
4. Feinberg AP and Vogelstein B (1983). A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal Biochem 132:6-13.
5. Fujita M, Inoue M, Tanizawa O, Iwamoto S, and Enomoto T (1992). Alterations of the p53 gene in human primary cervical carcinoma with and without human papillomavirus infection. Cancer Res 52:5323-5328.
6. Holmen SL, Vanbrockin MW, Eversole RR, Stapleton SR, and Ginsberg LC (1995). Efficient lipid-mediated transfection of DNA into primary rat hepatocytes. In Vitro Cell Dev Biol Anim 31:347-351.
7. Kim JW, Cho YH, Lyu MS, Lee CG, Jung JK, Kim SJ, and Namkoong SE (1995). Establishment and characterization of a cell line (CUMC-3) derived from a human squamous carcinoma of the uterine cervix. Gynecol Oncol 57:47-60.
8. Kim JW, Lee CG, Cho YH, Kim JH, Kim SJ, Kim HK, Park TC, Song SK, and Namkoong SE (1996). CUMC-6, a new diploid human cell line derived from a squamous carcinoma of the uterine cervix. Gynecol Oncol 62:230-240.
9. Kristensen GB, Holm R, Abeler VM, and Trop CG (1996). Evaluation of the prognostic significance of cathepsin D, epidermal growth factor receptor, and c-erbB-2 in early cervical squamous cell carcinoma: An immunohistochemical study. Cancer 78:433-440.
10. Laemmli UK (1970). Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680-685.
11. Liang P and Pardee AB (1992). Differential display of eukaryotic messenger RNA by means of the polymerase chain reaction. Science 257:967-971.
12. Liotta LA, Tryggvason K, Garbisa S, Ian H, Foltz CM, and Shafie S (1980). Metastatic potential correlates with enzymatic degradation of basement membrane collagen. Nature 284:67-68.
13. Martorana AM, Zheng G, Crowe TC, O'Grady RL, and Lyons JG (1998). Epithelial cells up-regulate matrix metalloproteinases in cells within the same mammary carcinoma that have undergone an epithelial-mesenchymal transition. Cancer Res 58:4970-4979.
14. Merzak A, Koocheckpour S, and Pilkington GJ (1994). CD44 mediates human glioma cell adhesion and invasion in vitro. Cancer Res 54:3988-3992.
15. Ng SY, Gunning P, Eddy R, Ponte P, Leavitt J, Shows T, and Kedes L (1985). Evolution of the functional human beta-actin gene and its multi-pseudogene family: conservation of non-coding regions and chromosomal dispersion of pseudogenes. Mol Cell Biol 5:2720-2732.
16. Park TW, Fujiwara H, and Wright TC (1995). Molecular biology of cervical cancer and its precursors. Cancer 76: 1902-1913.
17. Peifer M (1997). Beta-catenin as oncogene: the smoking gun. Science 275:1752-1753.
18. Sambrook J, Fritsch EF, and Maniatis T (1989). Molecular cloning: A laboratory manual. New York: Cold Spring Harbor Laboratory.
19. Sato H, Takino T, Okada Y, Cao J, Shinagawa A, Yamamoto E, and Seiki M (1994). A matrix metalloproteinase expressed on the surface of invasive tumor cells. Nature 370:61-65.
20. Stetler-Stevenson WG, Brown PD, Onisto M, Levy AT, and Liotta LA (1990). Tissue inhibitor of metalloproteinase-2 (TIMP-2) mRNA expression in tumor cell lines and human tumor tissues. J Biol Chem 23:13933-13938.
21. Stetler-Stevenson WG, Talano JA, Gallager ME, Krutzsch HC, and Liotta LA (1991). Inhibition of human type IV collagenase by a highly conserved peptide sequence derived from its prosegment. Am J Med Sci 302:163-170.
22. Takayama T, Shiozaki H, Shibamoto S, Oka H, Kimura Y, Tamura S, Inoue M, Monden T, Ito F, and Monden M (1996). Beta-catenin expression in human cancers. Am J Pathol 148:39-46.
23. Tewari M, Yu M, Ross B, Dean C, Giordano A, and Rubin R (1997). AAC-11, a novel cDNA that inhibits apoptosis after growth factor withdrawal. Cancer Res 57:4063-4069.
24. Tryggvason K, Hoyhtya M, and Pyke C (1993). Type IV collagenase in invasive tumors. Breast Cancer Res Treat 24:209-218.
25. Valente P, Fassina G, Melchiori A, Masiello L, Cilli M, Vacca A, Onisto M, Santi L, Stetler-Stevenson WG, and Albini A (1998). TIMP-2 overexpression reduces invasion and angiogenesis and protects B16F10 melanoma cells from apoptosis. Int J Cancer 75:246-253.
26. Wright TC, Ferenczy AF, and Kurman RJ (1994). Precancerous lesions of the cervix. In: Kurman RJ, editor. Blaustein's pathology of the female genital tract. New York: Springer-Verlag, 229-278.
27. zur Hausen H (1991). Viruses in human cancer. Science 254:1167-1173.