-
4
-
-
0000140697
-
Developing antisense oligonucleotides from the laboratory to clinical trials
-
Szymkoswki, D.E. 1996. Developing antisense oligonucleotides from the laboratory to clinical trials. Drug Discovery Today 1:415-428.
-
(1996)
Drug Discovery Today
, vol.1
, pp. 415-428
-
-
Szymkoswki, D.E.1
-
5
-
-
0030004872
-
Facilitating oligonucleotide delivery: Helping antisense deliver on its promise
-
Gewirtz, A.M., Stein, C.A., and Glazer, P.M. 1996. Facilitating oligonucleotide delivery: Helping antisense deliver on its promise. Proc. Natl. Acad. Sci. USA 93:3161-3163.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 3161-3163
-
-
Gewirtz, A.M.1
Stein, C.A.2
Glazer, P.M.3
-
6
-
-
0029268478
-
Inhibition of viral growth by antisense olginucleotides directed against the IE110 and the UL30 mRNA of Herpes Simplex Virus type-1
-
Peyman, A., Helsberg, M., Kretzschmar, G., Mag, M., Grabley, S., and Uhlmann, E. 1995. Inhibition of viral growth by antisense olginucleotides directed against the IE110 and the UL30 mRNA of Herpes Simplex Virus type-1. Biol. Chem 376:195-198.
-
(1995)
Biol. Chem
, vol.376
, pp. 195-198
-
-
Peyman, A.1
Helsberg, M.2
Kretzschmar, G.3
Mag, M.4
Grabley, S.5
Uhlmann, E.6
-
7
-
-
0029977448
-
Antitumor activity of a phosphorothioate antisense oligodeoxynucleotide targeted against C-raf kinase
-
Monia, B.P., Johnston, J.F., Geiger, T., Muller, M., and Fabbro, D. 1996. Antitumor activity of a phosphorothioate antisense oligodeoxynucleotide targeted against C-raf kinase. Nat. Med. 2:668-675.
-
(1996)
Nat. Med.
, vol.2
, pp. 668-675
-
-
Monia, B.P.1
Johnston, J.F.2
Geiger, T.3
Muller, M.4
Fabbro, D.5
-
8
-
-
0028292570
-
Inhibition of protein kinase C-α expression in human A549 cells by antisense oligonucleotides inhibits induction of intercellular adhesion molecule 1 (ICAM-1) mRNA by phorbol esters
-
Dean, N.M., McKay, R., Condon, T.P., and Bennett, C.F. 1994. Inhibition of protein kinase C-α expression in human A549 cells by antisense oligonucleotides inhibits induction of intercellular adhesion molecule 1 (ICAM-1) mRNA by phorbol esters. J. Biol. Chem. 269:16416-16424.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 16416-16424
-
-
Dean, N.M.1
McKay, R.2
Condon, T.P.3
Bennett, C.F.4
-
9
-
-
0029938209
-
Potent antisense oligonucleotides to the human multidrug resistance-1 mRNA are rationally selected by mapping RNA-accessible sites with oligonucleotide libraries
-
Ho, S.P., Britton, D.H.O., Stone, B.A., Behrens, D.L., Leffet, L.M., Hobbs, F.W., et al. 1996. Potent antisense oligonucleotides to the human multidrug resistance-1 mRNA are rationally selected by mapping RNA-accessible sites with oligonucleotide libraries. Nucl. Acids Res. 24:1901-1907.
-
(1996)
Nucl. Acids Res.
, vol.24
, pp. 1901-1907
-
-
Ho, S.P.1
Britton, D.H.O.2
Stone, B.A.3
Behrens, D.L.4
Leffet, L.M.5
Hobbs, F.W.6
-
10
-
-
10544245678
-
Altered mRNA splicing and inhibition of human E-selectin expression by an antisense oligonucleotide in human umbilical vein endothelial cells
-
Condon, T.P. and Bennett, C.F. 1996. Altered mRNA splicing and inhibition of human E-selectin expression by an antisense oligonucleotide in human umbilical vein endothelial cells. J. Biol. Chem. 271:30398-30403.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 30398-30403
-
-
Condon, T.P.1
Bennett, C.F.2
-
11
-
-
0027168725
-
Evaluation of 2′-modified oligonucleotides containing 2′-deoxy gaps as antisense inhibitors of gene expression
-
Monia, B.P., Lesnik, E.A., Gonzalez, C., Lima, W.F., McGee, D., Guinosso, C.J., et al. 1993. Evaluation of 2′-modified oligonucleotides containing 2′-deoxy gaps as antisense inhibitors of gene expression. J. Biol. Chem. 268:14514-14522.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 14514-14522
-
-
Monia, B.P.1
Lesnik, E.A.2
Gonzalez, C.3
Lima, W.F.4
McGee, D.5
Guinosso, C.J.6
-
12
-
-
0029089239
-
Detection of ribonuclease H-generated mRNA fragments in human leukemia cells following reversible membrane permeabilization in the presence of antisense oligodeoxynucleotides
-
Giles, R.V., Spiller, D.G., and Tidd, D.M. 1995. Detection of ribonuclease H-generated mRNA fragments in human leukemia cells following reversible membrane permeabilization in the presence of antisense oligodeoxynucleotides. Antisense Res. Dev. 5:23-31.
-
(1995)
Antisense Res. Dev.
, vol.5
, pp. 23-31
-
-
Giles, R.V.1
Spiller, D.G.2
Tidd, D.M.3
-
13
-
-
0023650861
-
Sequence-dependent hydrolysis of RNA using modified oligonucleotide splints and RNase H
-
Inoue, H., Hayase, Y., Iwai, S., and Ohtsuka, E. 1987. Sequence-dependent hydrolysis of RNA using modified oligonucleotide splints and RNase H. FEBS Lett. 215:327-330.
-
(1987)
FEBS Lett.
, vol.215
, pp. 327-330
-
-
Inoue, H.1
Hayase, Y.2
Iwai, S.3
Ohtsuka, E.4
-
14
-
-
0029619816
-
Kinetic characteristics of Escherichia coli RNase H: Cleavage of various antisense oligonucleotide-RNA duplexes
-
Crooke, S.T., Lemonidis, K.M., Neilson, L., Griffey, R., Lesnik, E.A., and Monia, B.P. 1995. Kinetic characteristics of Escherichia coli RNase H: cleavage of various antisense oligonucleotide-RNA duplexes. Biochemistry Journal 312:599-608.
-
(1995)
Biochemistry Journal
, vol.312
, pp. 599-608
-
-
Crooke, S.T.1
Lemonidis, K.M.2
Neilson, L.3
Griffey, R.4
Lesnik, E.A.5
Monia, B.P.6
-
15
-
-
0030849094
-
The influence of antisense oligonucleotide-induced RNA structure on Escherichia coli RNase H1 activity
-
Lima, W.F., Mohan, V., and Crooke, S.T. 1997. The influence of antisense oligonucleotide-induced RNA structure on Escherichia coli RNase H1 activity. J. Biol. Chem. 272:18191-18199.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 18191-18199
-
-
Lima, W.F.1
Mohan, V.2
Crooke, S.T.3
-
16
-
-
0028180664
-
Intracerebroventricular administration of AT, receptor antisense oligonucleotides inhibits the behavioral actions of angiotensin II
-
Sakai, R.R., He, P.F., Yang, X.D., Ma, L.Y., Guo, Y.F., Reilly, J.J., et al. 1994. Intracerebroventricular administration of AT, receptor antisense oligonucleotides inhibits the behavioral actions of angiotensin II. J. Neurochem. 62:2053-2056.
-
(1994)
J. Neurochem.
, vol.62
, pp. 2053-2056
-
-
Sakai, R.R.1
He, P.F.2
Yang, X.D.3
Ma, L.Y.4
Guo, Y.F.5
Reilly, J.J.6
-
17
-
-
0031032603
-
Combinatorial screening and rational optimization for hybridization to folded hepatitis C virus RNA of oligonucleotides with biological antisense activity
-
Lima, W.F., Brown-Driver, V., Fox, M., Hanecak, R., and Bruice, T.W. 1997. Combinatorial screening and rational optimization for hybridization to folded hepatitis C virus RNA of oligonucleotides with biological antisense activity. J. Biol. Chem. 272:626-638.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 626-638
-
-
Lima, W.F.1
Brown-Driver, V.2
Fox, M.3
Hanecak, R.4
Bruice, T.W.5
-
18
-
-
0030952735
-
Probing accessible sites for ribozymes on human acetylcholinesterase RNA
-
Birikh, K.R., Berlin, Y.A., Soreq, H., and Eckstein, F. 1997. Probing accessible sites for ribozymes on human acetylcholinesterase RNA. RNA 3:429-437.
-
(1997)
RNA
, vol.3
, pp. 429-437
-
-
Birikh, K.R.1
Berlin, Y.A.2
Soreq, H.3
Eckstein, F.4
-
19
-
-
0030902471
-
Selecting effective antisense reagents on combinatorial oligonucleotide arrays
-
Milner, N., Mir, K.U., and Southern, E.M. 1997. Selecting effective antisense reagents on combinatorial oligonucleotide arrays. Nature Biotechnology 15:537-544.
-
(1997)
Nature Biotechnology
, vol.15
, pp. 537-544
-
-
Milner, N.1
Mir, K.U.2
Southern, E.M.3
-
20
-
-
0028943217
-
Selection of efficient cleavage sites in target RNAs by using a ribozyme expression library
-
Lieber, A. and Strauss, M. 1995. Selection of efficient cleavage sites in target RNAs by using a ribozyme expression library. Mol. Cell. Biol. 15:540-551.
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 540-551
-
-
Lieber, A.1
Strauss, M.2
-
21
-
-
0027340373
-
Characterization of angiotensin AT1 a receptor isoform by its ligand binding signature
-
Chiu, A.T., Dunscomb, J., McCall, D.E., Benfield, P., Baubonis, W., and Sauer, B. 1993. Characterization of angiotensin AT1 a receptor isoform by its ligand binding signature. Regulatory Peptides 44:141-147.
-
(1993)
Regulatory Peptides
, vol.44
, pp. 141-147
-
-
Chiu, A.T.1
Dunscomb, J.2
McCall, D.E.3
Benfield, P.4
Baubonis, W.5
Sauer, B.6
-
22
-
-
0027340373
-
Characterization of angiotensin AT1a receptor isoform by its ligand binding signature
-
Chiu, A.T., Dunscomb, J., McCall, D.E., Benfield, P., Baubonis, W., and Sauer, B. 1993. Characterization of angiotensin AT1a receptor isoform by its ligand binding signature. Regul. Pept. 44:141-147.
-
(1993)
Regul. Pept.
, vol.44
, pp. 141-147
-
-
Chiu, A.T.1
Dunscomb, J.2
McCall, D.E.3
Benfield, P.4
Baubonis, W.5
Sauer, B.6
|