Cell-specific expression of the diphtheria toxin A-chain coding sequence under the control of the upstream region of the human alpha-fetoprotein gene

Journal of Surgical Oncology

Volumn 70, Issue 3, 1999, Pages 145-149

  Murayama, Yoshihiko ^a,d   Tadakuma, Takushi ^b   Kunitomi, Michito ^b   Kumai, Koichiro ^a   Tsutsui, Ken ^c   Yasuda, Tatsuji ^c   Kitajima, Masaki ^a  

^a KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b NATIONAL DEFENSE MEDICAL COLLEGE   (Japan)

^c OKAYAMA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^d Nerima General Hospital   (Japan)

Author keywords

Alpha fetoprotein; Diphtheria toxin; Gene therapy

Indexed keywords

ALPHA FETOPROTEIN; DIPHTHERIA TOXIN;

ARTICLE; CELL SPECIFICITY; CONTROLLED STUDY; ENHANCER REGION; GENE EXPRESSION; GENE THERAPY; GENE TRANSFER; HUMAN; HUMAN CELL; PLASMID; PRIORITY JOURNAL; PROMOTER REGION; REPORTER GENE; SUICIDE GENE;

ALPHA-FETOPROTEINS; CARCINOMA, HEPATOCELLULAR; CHLORAMPHENICOL O-ACETYLTRANSFERASE; DIPHTHERIA TOXIN; ENHANCER ELEMENTS (GENETICS); GENE THERAPY; HUMANS; LIVER NEOPLASMS; PEPTIDE FRAGMENTS; PROMOTER REGIONS (GENETICS); TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0033050462     PISSN: 00224790     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-9098(199903)70:3<145::AID-JSO1>3.0.CO;2-O     Document Type: Article

References (37)

1. Maxwell IH, Glode LM, Maxwell F: Expression of the diphtheria toxin A-chain coding sequence under control of promoters and enhancers from immunoglobulin genes as a means of directing toxicity to B-lymphoid cells. Cancer Res 1991;51:4299-4304.
2. Caruso M, Panis Y, Singh, G. et al.: Regression of an established macroscopic liver tumor by in vivo retroviral-mediated transfer of a suicide gene. Proc Natl Acad Sei USA 1993;90:7024-7028.
3. Kuriyama S, Nakatani T, Masui K, et al.: Bystander effect caused by suicide gene expression indicates the feasibility of gene therapy for hepatocellular carcinoma. Hum Gene Ther 1995;8:349-358.
4. Brand K, Arnold W, Bartels T, et al.: Liver-associated toxicity of the HSV-tk/GCV approach and adenoviral vectors. Cancer Gene Ther 1997;4:9-16.
5. Nagy H, Panis Y, Fabre M, et al.: Are hepatomas a good target for suicide gene therapy? An experimental study in rats using retroviral-mediated transfer of thymidine kinase gene. Surgery 1998; 123:19-24.
6. Collier RJ: Diphtheria toxin: Mode of action and structure. Bacteriol Rev 1975;39:54-85.
7. Greenfield L, Bjorn MJ, Horn G, et al.: Nucleotide sequence of the structural gene for diphtheria toxin carried by corynebacteriophage β. Proc Natl Acad Sei USA 1983;80:6853-6857.
8. Kaczorek M, Delpeyroux F, Chenciner M, et al.: Nucleotide sequence and expression of the diphtheria tox 228 gene in Escherichia coli. Science 1983;22:855-858.
9. Pappenheimer AM Jr: Diphtheria toxin. Annu Rev Biochem 1977; 46:69-94.
10. Moehring TJ, Danley DE, Moehring JM: In vitro biosynthesis of diphthamide, studied with mutant Chinese hamster ovary cells resistant to diphtheria toxin. Mol Cell Biol 1984;4:642-650.
11. Kohno K, Uchida T, Ohkubo H, et al.: Amino acid sequence of mammalian elongation factor 2 deduced from the cDNA sequence: Homology with GTP-binding proteins. Proc Natl Acad Sci USA 1986;83:4978-4982.
12. Yamaizumi M, Mekada E, Uchida E, et al.: One molecule of diphtheria toxin fragment A introduced into a cell can kill the cell. Cell 1978;15:245-250.
13. Palmiter RD, Behringer RR, Quaife CJ, et al.: Cell lineage ablation in transgenic mice by cell-specific expression of a toxin gene. Cell 1987;50:435-443.
14. Breitman ML, Clapoff S, Rossant J, et al.: Genetic ablation: Programmed lineage suicide by tissue-specific expression of the diphtheria toxin A gene in transgenic mice. Science 1987;238:1563-1565.
15. Maxwell F, Maxwell IH, Glode M: Cloning, sequence determination, and expression in transfected cells of the coding sequence for the tox 176 attenuated diphtheria toxin A chain. Mol Cell Biol 1987;7:1576-1579.
16. Abelev GI: Alpha-fetoprotein in ontogenesis and its association with malignant tumors. Adv Cancer Res 1971;14:295-355.
17. Camper SA, Godbout R, Tilghman SM: The developmental regulation of albumin and alpha-fetoprotein gene expression. Prog Nucleic Acid Res Mol Biol 1989;36:131-144.
18. Belanger L, Baril P, Gurtin M, et al.: Oncodevelopmental and hormonal regulation of alpha-fetoprotein gene expression. Adv Enzyme Regul 1983;23:73-99.
19. Nahon J-L: The regulation of albumin and alpha-fetoprotein gene expression in mammals. Biochimie 1987;69:445-459.
20. Tamaoki T, Fausto N: Expression of the alpha-fetoprotein gene during development, regeneration and carcinogenesis. In Stein G, Stein J (eds): "Recombinant DNA and Cell Proliferation." New York: Academic Press, 1984:145-168.
21. Tilghman SM, Belayew A: Transcriptional control of the murine albumin/alpha-fetoprotein locus during development. Proc Natl Acad Sei USA 1982;79:5254-5257.
22. Watanabe K, Saito A, Tamaoki T: Cell-specific enhancer activity in a far upstream region of the human alpha-fetoprotein gene. J Biol Chem 1987;262:4812-4818.
23. Kakidani H, Watari S, Yasuda T, et al.: Suppressive effect of liposome containing DNA coding for diphtheria toxin A-chain on cells transformed with bovine leukemia virus. Microbiol Immunol 1993;37:713-720.
24. Nakabayashi H, Takeda K, Yamane T, et al.: Phenotypic stability of a human hepatoma cell line. HuH-7, in long-term culture with chemically defined medium. Gann 1984;75:151-158.
25. Aden DP, Fogel A, Plotkin S: Controlled synthesis of HBs-Ag in a differentiated human liver carcinoma-derived cell line. Nature 1979;282:615-616.
26. Behr JP, Demeneix B, Loeffler JP, et al.: Efficient gene transfer into mammalian primary endocrine cells with lipopolyamine-coated DNA. Proc Natl Acad Sei USA 1989;86:6982-6986.
27. Gao X, Huang L: A novel cationic liposome reagent for efficient transfection of mammalian cells. Biochem Biophys Res Commun 1991;179:280-285.
28. Gorman CM, Moffat LF, Howard BH: Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells. Mol Cell Biol 1982;2:1044-1051.
29. Crystal RG: Transfer of genes to humans: Early lessons and obstacles to success. Science 1995;270:404-410.
30. Lee J-T, Watari S, Yasuda T, et al.: Evaluation of cationic liposomes for delivery of diphtheria toxin A-chain gene to cells infected with bovine leukemia virus. Jpn J Vet Sci 1997;59:169-174.
31. Kanai F, Lan K-H, Shiratori Y, et al.: In vivo gene therapy for alpha-fetoprotein-producing hepatocellular carcinoma by adenovirus-mediated transfer of cytosine deaminase gene. Cancer Res 1997;57:461-465.
32. Ido A, Nakata K, Kato Y, et al.: Gene therapy for hepatoma cells using a retrovirus vector carrying herpes simplex virus thymidine kinase gene under the control of human alpha-fetoprotein gene promoter. Cancer Res 1995;55:3105-3109.
33. Tanaka T, Kanai F, Okabe S, et al.: Adenovirus-mediated prodrug gene therapy for carcinoembryonic antigen-producing human gastric carcinoma cells in vitro. Cancer Res 1996;56:1341-1345.
34. Rodriguez R, Schuur ER, Lin HY, et al.: Prostate attenuated replication competent adenovirus (ARCA) CN706: A selective cytotoxic for prostate-specific antigen-positive prostate cancer cells. Cancer Res 1997;57:2559-2563.
35. Huber BE, Richards CA, Krenitsky TA: Retroviral-mediated gene therapy for the treatment of hepatocellular carcinoma: An innovative approach for cancer therapy. Proc Natl Acad Sci USA 1991;88:8039-8043.
36. Kaneko S, Hallenbeck P, Kotani T, et al.: Adenovirus-mediated gene therapy of hepatocellular carcinoma using cancer-specific gene expression. Cancer Res 1995;55:5283-5287.
37. Konno H, Suzuki H, Tadakuma T, et al.: Anti-tumor effect of adriamycin entrapped in liposomes conjugated with anti-human alpha-fetoprotein monoclonal antibody. Cancer Res 1987;47: 4471-4477.