-
1
-
-
0030239828
-
Induction of NK activity in murine and human cells by CpG motifs in oligodeoxynucleotides and bacterial DNA
-
Ballas, Z. K., W. L. Rasmussen, and A. M. Krieg. Induction of NK activity in murine and human cells by CpG motifs in oligodeoxynucleotides and bacterial DNA. J. Immunol. 157: 1840-1845, 1996.
-
(1996)
J. Immunol.
, vol.157
, pp. 1840-1845
-
-
Ballas, Z.K.1
Rasmussen, W.L.2
Krieg, A.M.3
-
2
-
-
17344368550
-
Effects of complement depletion on the pharmacokinetics and gene delivery mediated by cationic lipid DNA complexes
-
Barron, L. G., K. B. Meyer, and F. C. Szoka. Effects of complement depletion on the pharmacokinetics and gene delivery mediated by cationic lipid DNA complexes. Hum. Gene Ther. 9: 315-323, 1998.
-
(1998)
Hum. Gene Ther.
, vol.9
, pp. 315-323
-
-
Barron, L.G.1
Meyer, K.B.2
Szoka, F.C.3
-
3
-
-
0028269736
-
Protection of rabbit lungs from endotoxin injury by in vivo hyperexpression of the prostaglandin G/H synthase gene
-
Conary, J. T., R. E. Parker, B. W. Christman, R. D. Faulks, G. A. King, B. O. Meyrick, and K. L. Brigham. Protection of rabbit lungs from endotoxin injury by in vivo hyperexpression of the prostaglandin G/H synthase gene. J. Clin. Invest. 93: 1834-1840, 1994.
-
(1994)
J. Clin. Invest.
, vol.93
, pp. 1834-1840
-
-
Conary, J.T.1
Parker, R.E.2
Christman, B.W.3
Faulks, R.D.4
King, G.A.5
Meyrick, B.O.6
Brigham, K.L.7
-
4
-
-
0030749978
-
Spatial-temporal patterns of gene expression in mouse skeletal muscle after injection of lacz plasmid DNA
-
Doh, S. G., H. L. Vahlsing, J. Hartikka, X. Liang, and M. Manthorpe. Spatial-temporal patterns of gene expression in mouse skeletal muscle after injection of lacZ plasmid DNA. Gene Ther. 4: 648-663, 1997.
-
(1997)
Gene Ther.
, vol.4
, pp. 648-663
-
-
Doh, S.G.1
Vahlsing, H.L.2
Hartikka, J.3
Liang, X.4
Manthorpe, M.5
-
5
-
-
0032080647
-
Cationic lipids enhance cytokine and cell influx levels in the lung following administration of plasmidcationic lipid complexes
-
Freimark, B. D., H. P. Blezinger, V. J. Florack, J. L. Nordstrom, S. D. Long, D. S. Deshpande, S. Nochumson, and K. L. Petrak. Cationic lipids enhance cytokine and cell influx levels in the lung following administration of plasmidcationic lipid complexes. J. Immunol. 160: 4580-4586, 1998.
-
(1998)
J. Immunol.
, vol.160
, pp. 4580-4586
-
-
Freimark, B.D.1
Blezinger, H.P.2
Florack, V.J.3
Nordstrom, J.L.4
Long, S.D.5
Deshpande, D.S.6
Nochumson, S.7
Petrak, K.L.8
-
6
-
-
0030729199
-
Repression of retrovirus-mediated transgene expression by interferons: Implications for gene therapy
-
Ghazizadeh, S., J. M. Carroll, and L. B. Taichman. Repression of retrovirus-mediated transgene expression by interferons: implications for gene therapy. J. Virol. 71: 9163-9169, 1997.
-
(1997)
J. Virol.
, vol.71
, pp. 9163-9169
-
-
Ghazizadeh, S.1
Carroll, J.M.2
Taichman, L.B.3
-
7
-
-
0030459813
-
Synergy between tumor necrosis factor alpha and interleukin 1 beta in inducing transcriptional down-regulation of muscarinic M2 receptor gene expression. Involvement of protein kinase A and ceramide pathways
-
Haddad, E. B., J. Rousell, M. A. Lindsay, and P. J. Barnes. Synergy between tumor necrosis factor alpha and interleukin 1 beta in inducing transcriptional down-regulation of muscarinic M2 receptor gene expression. Involvement of protein kinase A and ceramide pathways. J. Biol. Chem. 271: 32586-32592, 1996.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 32586-32592
-
-
Haddad, E.B.1
Rousell, J.2
Lindsay, M.A.3
Barnes, P.J.4
-
8
-
-
0030784482
-
Lipopolysaccharide induces disseminated endothelial apoptosis requiring ceramide generation
-
Haimovitz-Friedman, A., C. Cordon-Cardo, S. Bayoumy, M. Garzotto, M. McLoughlin, R. Gallily, C. K. Edwards III, E. H. Schuchman, Z. Fuks, and R. Kolesnick. Lipopolysaccharide induces disseminated endothelial apoptosis requiring ceramide generation. J. Exp. Med. 186: 1831-1841, 1997.
-
(1997)
J. Exp. Med.
, vol.186
, pp. 1831-1841
-
-
Haimovitz-Friedman, A.1
Cordon-Cardo, C.2
Bayoumy, S.3
Garzotto, M.4
McLoughlin, M.5
Gallily, R.6
Edwards C.K. III7
Schuchman, E.H.8
Fuks, Z.9
Kolesnick, R.10
-
9
-
-
0030950392
-
In vivo gene transfer by intravenous administration of stable cationic lipid/DNA complex
-
Hofland, H. E. J., D. Nagy, J. J. Liu, K. Spratt, Y. L. Lee, O. Danos, and S. M. Sullivan. In vivo gene transfer by intravenous administration of stable cationic lipid/DNA complex. Pharm. Res. 14: 742-749, 1997.
-
(1997)
Pharm. Res.
, vol.14
, pp. 742-749
-
-
Hofland, H.E.J.1
Nagy, D.2
Liu, J.J.3
Spratt, K.4
Lee, Y.L.5
Danos, O.6
Sullivan, S.M.7
-
10
-
-
0031023264
-
Stabilization of cationic liposome-plasmid DNA complexes by polyamines and poly(ethylene glycol)-phospholipid conjugates for efficient in vivo gene delivery
-
Hong, K. L., W. W. Zheng, A, Baker, and D. Papahadjopoulos. Stabilization of cationic liposome-plasmid DNA complexes by polyamines and poly(ethylene glycol)-phospholipid conjugates for efficient in vivo gene delivery. FEBS Lett. 400: 233-237, 1997.
-
(1997)
FEBS Lett.
, vol.400
, pp. 233-237
-
-
Hong, K.L.1
Zheng, W.W.2
Baker, A.3
Papahadjopoulos, D.4
-
11
-
-
0031183472
-
Liposomal gene delivery - A complex package
-
Huang, L., and S. Li. Liposomal gene delivery - a complex package. Nat. Biotechnol. 15: 620-621, 1997.
-
(1997)
Nat. Biotechnol.
, vol.15
, pp. 620-621
-
-
Huang, L.1
Li, S.2
-
12
-
-
0031569601
-
Contribution of CpG motifs to the immunogenicity of DNA vaccines
-
Klinman, D. M., G. Yamshchikov, and Y. Ishigatsubo. Contribution of CpG motifs to the immunogenicity of DNA vaccines. J. Immunol. 158: 3635-3639, 1997.
-
(1997)
J. Immunol.
, vol.158
, pp. 3635-3639
-
-
Klinman, D.M.1
Yamshchikov, G.2
Ishigatsubo, Y.3
-
13
-
-
0028931102
-
CpG motifs in bacterial DNA trigger direct B-cell activation
-
Krieg, A. M., A. K. Yi, S. Matson, T. J. Waldschmidt, G. A. Bishop, R. Teasdale, G. A. Koretzky, and D. M. Klinman. CpG motifs in bacterial DNA trigger direct B-cell activation. Nature 374: 546-549, 1995.
-
(1995)
Nature
, vol.374
, pp. 546-549
-
-
Krieg, A.M.1
Yi, A.K.2
Matson, S.3
Waldschmidt, T.J.4
Bishop, G.A.5
Teasdale, R.6
Koretzky, G.A.7
Klinman, D.M.8
-
14
-
-
0030866645
-
In vivo gene transfer via intravenous administration of cationic lipid-protamine-DNA (LPD) complexes
-
Li, S., and L. Huang. In vivo gene transfer via intravenous administration of cationic lipid-protamine-DNA (LPD) complexes. Gene Ther. 4: 891-900, 1997.
-
(1997)
Gene Ther.
, vol.4
, pp. 891-900
-
-
Li, S.1
Huang, L.2
-
15
-
-
0031851486
-
Characterization of cationic lipid-protamine-DNA (LPD) complexes for intravenous gene delivery
-
Li, S., M. A. Rizzo, S. Bhattacharya, and L. Huang. Characterization of cationic lipid-protamine-DNA (LPD) complexes for intravenous gene delivery. Gene Ther. 5: 930-937, 1998.
-
(1998)
Gene Ther.
, vol.5
, pp. 930-937
-
-
Li, S.1
Rizzo, M.A.2
Bhattacharya, S.3
Huang, L.4
-
16
-
-
0032962978
-
Dynamic changes in the characteristics of cationic lipidic vectors after exposure to mouse serum: Implications for intravenous lipofection
-
In press
-
Li, S., W. C. Tseng, D. B. Stolz, S. P. Wu, S. C. Watkins, and L. Huang. Dynamic changes in the characteristics of cationic lipidic vectors after exposure to mouse serum: implications for intravenous lipofection. Gene Ther. In press.
-
Gene Ther.
-
-
Li, S.1
Tseng, W.C.2
Stolz, D.B.3
Wu, S.P.4
Watkins, S.C.5
Huang, L.6
-
17
-
-
0030946393
-
Peripheral blood mono-nuclear cells induce programmed cell death in human endothelial cells and may prevent repair: Role of cytokines
-
Lindner, H., E. Holler, B. Ertl, G. Multhoff, M. Schreglmann, I. Klauke, S. Schultz-Hector, and G. Eissner. Peripheral blood mono-nuclear cells induce programmed cell death in human endothelial cells and may prevent repair: role of cytokines. Blood 89: 1931-1938, 1997.
-
(1997)
Blood
, vol.89
, pp. 1931-1938
-
-
Lindner, H.1
Holler, E.2
Ertl, B.3
Multhoff, G.4
Schreglmann, M.5
Klauke, I.6
Schultz-Hector, S.7
Eissner, G.8
-
18
-
-
0030813879
-
Factors controlling the efficiency of cationic lipid-mediated transfection in vivo via intravenous administration
-
Liu, F., H. Qi, L. Huang, and D. Liu. Factors controlling the efficiency of cationic lipid-mediated transfection in vivo via intravenous administration. Gene Ther. 4: 517-523, 1997.
-
(1997)
Gene Ther.
, vol.4
, pp. 517-523
-
-
Liu, F.1
Qi, H.2
Huang, L.3
Liu, D.4
-
19
-
-
0031049765
-
Factors influencing the efficiency of cationic liposome-mediated intravenous gene delivery
-
Liu, Y., L. C. Mounkes, H. D. Liggitt, C. S. Brown, I. Solodin, T. D. Heath, and R. J. Debs. Factors influencing the efficiency of cationic liposome-mediated intravenous gene delivery. Nat. Biotechnol. 15: 167-173, 1997.
-
(1997)
Nat. Biotechnol.
, vol.15
, pp. 167-173
-
-
Liu, Y.1
Mounkes, L.C.2
Liggitt, H.D.3
Brown, C.S.4
Solodin, I.5
Heath, T.D.6
Debs, R.J.7
-
20
-
-
25544432128
-
RB-mediated suppression of spontaneous multiple neuroendocrine neoplasia and lung metastases in RB+/-mice
-
In press
-
Nikitin, A. Y., M. I. Juarez-Perez, S. Li, L. Huang, and W. H. Lee. RB-mediated suppression of spontaneous multiple neuroendocrine neoplasia and lung metastases in RB+/-mice. Proc. Natl. Acad. Sci. USA. In press.
-
Proc. Natl. Acad. Sci. USA
-
-
Nikitin, A.Y.1
Juarez-Perez, M.I.2
Li, S.3
Huang, L.4
Lee, W.H.5
-
21
-
-
0031581174
-
Promoter attenuation in gene therapy: Interferon-gamma and tumor necrosis factor-alpha inhibit transgene expression
-
Qin, L., Y. Ding, D. R. Pahud, E. Chang, M. J. Imperiale, and J. S. Bromberg. Promoter attenuation in gene therapy: interferon-gamma and tumor necrosis factor-alpha inhibit transgene expression. Hum. Gene Ther. 8: 2019-2029, 1997.
-
(1997)
Hum. Gene Ther.
, vol.8
, pp. 2019-2029
-
-
Qin, L.1
Ding, Y.2
Pahud, D.R.3
Chang, E.4
Imperiale, M.J.5
Bromberg, J.S.6
-
24
-
-
8944253295
-
Immunostimulatory DNA sequences necessary for effective intradermal gene immunization
-
Sato, Y., M. Roman, H. Tighe, D. Lee, M. Corr, M. D. Nguyen, G. J. Silverman, M. Lotz, D. A. Carson, and E. Raz. Immunostimulatory DNA sequences necessary for effective intradermal gene immunization. Science 273: 352-354, 1996.
-
(1996)
Science
, vol.273
, pp. 352-354
-
-
Sato, Y.1
Roman, M.2
Tighe, H.3
Lee, D.4
Corr, M.5
Nguyen, M.D.6
Silverman, G.J.7
Lotz, M.8
Carson, D.A.9
Raz, E.10
-
25
-
-
16944364834
-
Basis of pulmonary toxicity associated with cationic lipid-mediated gene transfer to the mammalian lung
-
Scheule, R. K., J. A. St. George, R. G. Bagley, J. Marshall, J. M. Kaplan, G. Y. Akita, K. X. Wang, E. R. Lee, D. J. Harris, C. Jiang, N. S. Yew, A. E. Smith, and S. H. Cheng. Basis of pulmonary toxicity associated with cationic lipid-mediated gene transfer to the mammalian lung. Hum. Gene Ther. 8: 689-707, 1997.
-
(1997)
Hum. Gene Ther.
, vol.8
, pp. 689-707
-
-
Scheule, R.K.1
St. George, J.A.2
Bagley, R.G.3
Marshall, J.4
Kaplan, J.M.5
Akita, G.Y.6
Wang, K.X.7
Lee, E.R.8
Harris, D.J.9
Jiang, C.10
Yew, N.S.11
Smith, A.E.12
Cheng, S.H.13
-
26
-
-
0030859292
-
CpG motifs in bacterial DNA cause inflammation in the lower respiratory tract
-
Schwartz, D. A., T. J. Quinn, P. S. Thorne, S. Sayeed, A. K. Yi, and A. M. Krieg. CpG motifs in bacterial DNA cause inflammation in the lower respiratory tract. J. Clin. Invest. 100: 68-73, 1997.
-
(1997)
J. Clin. Invest.
, vol.100
, pp. 68-73
-
-
Schwartz, D.A.1
Quinn, T.J.2
Thorne, P.S.3
Sayeed, S.4
Yi, A.K.5
Krieg, A.M.6
-
27
-
-
0030668116
-
Characterization of cationic liposome-mediated gene transfer in vivo by intravenous administration
-
Song, Y. K., F. Liu, S. Y. Chu, and D. X. Liu. Characterization of cationic liposome-mediated gene transfer in vivo by intravenous administration. Hum. Gene Ther. 8: 1585-1594, 1997.
-
(1997)
Hum. Gene Ther.
, vol.8
, pp. 1585-1594
-
-
Song, Y.K.1
Liu, F.2
Chu, S.Y.3
Liu, D.X.4
-
28
-
-
0030816325
-
Macrophages sense pathogens via DNA motifs: Induction of tumor necrosis factor-alpha-mediated shock
-
Sparwasser, T., T. Miethke, G. Lipford, A. Erdmann, H. Hacker, K. Heeg, and H. Wagner. Macrophages sense pathogens via DNA motifs: induction of tumor necrosis factor-alpha-mediated shock. Eur. J. Immunol. 27: 1671-1679, 1997.
-
(1997)
Eur. J. Immunol.
, vol.27
, pp. 1671-1679
-
-
Sparwasser, T.1
Miethke, T.2
Lipford, G.3
Erdmann, A.4
Hacker, H.5
Heeg, K.6
Wagner, H.7
-
29
-
-
0030760143
-
Improved DNA: Liposome complexes for increased systemic delivery and gene expression
-
Templeton, N. S., D. D. Lasic, P. M. Frederik, H. H. Strey, D. D. Roberts, and G. N. Pavlakis. Improved DNA: liposome complexes for increased systemic delivery and gene expression. Nat. Biotechnol. 15: 647-652, 1997.
-
(1997)
Nat. Biotechnol.
, vol.15
, pp. 647-652
-
-
Templeton, N.S.1
Lasic, D.D.2
Frederik, P.M.3
Strey, H.H.4
Roberts, D.D.5
Pavlakis, G.N.6
-
30
-
-
0032543524
-
Synthesis and characterization of long chain alkyl acyl carnitine esters. Potentially biodegradable cationic lipids for use in gene delivery
-
Wang, J. K., X. Guo, Y. H. Xu, L. Barron, and F. C. Szoka. Synthesis and characterization of long chain alkyl acyl carnitine esters. Potentially biodegradable cationic lipids for use in gene delivery. J. Med. Chem. 41: 2207-2215, 1998.
-
(1998)
J. Med. Chem.
, vol.41
, pp. 2207-2215
-
-
Wang, J.K.1
Guo, X.2
Xu, Y.H.3
Barron, L.4
Szoka, F.C.5
-
31
-
-
0026464967
-
DNA from bacteria, but not from vertebrates, induces interferons, activates natural killer cells and inhibits tumor growth
-
Yamamoto, S., T. Yamamoto, S. Shimada, E. Kuramoto, O. Yano, T. Kataoka, and T. Tokunaga. DNA from bacteria, but not from vertebrates, induces interferons, activates natural killer cells and inhibits tumor growth. Microbiol. Immunol. 36: 983-997, 1992.
-
(1992)
Microbiol. Immunol.
, vol.36
, pp. 983-997
-
-
Yamamoto, S.1
Yamamoto, T.2
Shimada, S.3
Kuramoto, E.4
Yano, O.5
Kataoka, T.6
Tokunaga, T.7
-
32
-
-
0029891426
-
Direct gene transfer to mouse melanoma by intratumor injection of free DNA
-
Yang, J. P., and L. Huang. Direct gene transfer to mouse melanoma by intratumor injection of free DNA. Gene Ther. 3: 542-548, 1996.
-
(1996)
Gene Ther.
, vol.3
, pp. 542-548
-
-
Yang, J.P.1
Huang, L.2
-
33
-
-
0029670726
-
IFN-gamma promotes IL-6 and IgM secretion in response to CpG motifs in bacterial DNA and oligodeoxynucleotides
-
Yi, A. K., J. H. Chace, J. S. Cowdery, and A. M. Krieg. IFN-gamma promotes IL-6 and IgM secretion in response to CpG motifs in bacterial DNA and oligodeoxynucleotides. J. Immunol. 156: 558-564, 1996.
-
(1996)
J. Immunol.
, vol.156
, pp. 558-564
-
-
Yi, A.K.1
Chace, J.H.2
Cowdery, J.S.3
Krieg, A.M.4
-
34
-
-
0030772278
-
Pattern and kinetics of cytokine production following administration of phosphorothioate oligonucleotides in mice
-
Zhao, Q. Y., J. Temsamani, R. Z. Zhou, and S. Agrawal. Pattern and kinetics of cytokine production following administration of phosphorothioate oligonucleotides in mice. Antisense Nucleic Acid Drug Dev. 1: 495-502, 1997.
-
(1997)
Antisense Nucleic Acid Drug Dev.
, vol.1
, pp. 495-502
-
-
Zhao, Q.Y.1
Temsamani, J.2
Zhou, R.Z.3
Agrawal, S.4
-
35
-
-
0032103369
-
In vivo expression of neutrophil inhibitory factor via gene transfer prevents lipopolysaccharideinduced lung neutrophil infiltration and injury by a beta(2) integrin-dependent mechanism
-
Zhou, M. Y., S. K. Lo, M. Bergenfeldt, C. Tiruppathi, A. Jaffe, N. Xu, and A. B. Malik. In vivo expression of neutrophil inhibitory factor via gene transfer prevents lipopolysaccharideinduced lung neutrophil infiltration and injury by a beta(2) integrin-dependent mechanism. J. Clin. Invest. 101: 2427-2437, 1998.
-
(1998)
J. Clin. Invest.
, vol.101
, pp. 2427-2437
-
-
Zhou, M.Y.1
Lo, S.K.2
Bergenfeldt, M.3
Tiruppathi, C.4
Jaffe, A.5
Xu, N.6
Malik, A.B.7
-
36
-
-
0027313072
-
Systemic gene expression after intravenous DNA delivery into adult mice
-
Zhu, N., D. Liggitt, Y. Liu, and R. Debs. Systemic gene expression after intravenous DNA delivery into adult mice. Science 261: 209-211, 1993.
-
(1993)
Science
, vol.261
, pp. 209-211
-
-
Zhu, N.1
Liggitt, D.2
Liu, Y.3
Debs, R.4
|