In vivo gene delivery to the liver using reconstituted chylomicron remnants as a novel nonviral vector

Proceedings of the National Academy of Sciences of the United States of America

Volumn 94, Issue 26, 1997, Pages 14547-14552

  Hara, Toshifumi ^a,b   Tan, Yadi ^a   Huang, Leaf ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b TAISHO PHARMACEUTICAL CO LTD   (Japan)

Author keywords

Apolipoprotein; Cationic lipid; Emulsion; Gene transfer; Human 1 antitrypsin

Indexed keywords

ALPHA 1 ANTITRYPSIN; APOLIPOPROTEIN; CHYLOMICRON; DNA; LIPID;

ANIMAL TISSUE; ARTICLE; CLONING VECTOR; CONTROLLED STUDY; EMULSION; GENE EXPRESSION; GENE TRANSFER; LIVER; MOUSE; NONHUMAN; PRIORITY JOURNAL; TRANSGENE;

ALPHA 1-ANTITRYPSIN; ANIMALS; CHYLOMICRONS; FEMALE; GENE EXPRESSION; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; HUMANS; LIVER; MICE; PLASMIDS;

EID: 0031446338     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.94.26.14547     Document Type: Article

References (58)

1. Wilson, J. M. (1996) Nat. Genet. 12, 232-233.
2. Wilson, J. M., Grossman, M., Wu, C. H., Chowdhury, N. R., Wu, G. Y. & Chowdhury, J. R. (1992) J. Biol. Chem. 267, 963-967.
3. Ferkol, T., Lindberg, G. L., Ghen, J., Perales, J. C., Crawford, D. R., Ratnoff, O. D. & Hanson, R. W. (1993) FASEB J. 7, 1081-1091.
4. Kay, M. A., Baley, P., Rothemberg, S., Leland, F., Fleming, L., Ponder, K. P., Liu, T., Finegold, M., Darlington, G., Pokorny, W. & Woo, S. L. C. (1992) Proc. Natl. Acad. Sci. USA 89, 89-93.
5. Chao, J., Jin, L., Chen, L.-M., Chen, V. C. & Chao, L. (1996) Hum. Gene Ther. 7, 901-911.
6. Miller, D. G., Adam, M. A. & Miller, A. D. (1990) Mol. Cell. Biol. 10, 4239-4242.
7. Grossman, M., Raper, S. E., Kozarsky, K., Stein, E. A., Engelhardt, J. F., Muller, D., Lupien, P. J. & Wilson, J. M. (1994) Nat. Genet. 6, 335-341.
8. Ledley, F., Darlington, G., Hahn, T. & Woo, S. (1987) Proc. Natl. Acad. Sci. USA 84, 5335-5339.
9. Ferry, N., Duplessis, O., Houssin, D., Danos, O. & Heard, J.-L. (1991) Proc. Natl. Acad. Sci. USA 88, 8377-8381.
10. Kay, M. A., Li, Q. T., Liu, T. J., Leland, F., Finegold, M. & Woo, S. L. C. (1992) Hum. Gene Ther. 3, 641-647.
11. Rosefeld, M. A., Siegfried, W., Yoshimura, K., Yoneyama, K., Fukayama, M., Stier, L. E., Paakko, P. K., Gilardi, P., Stratford-Perricaudet, L. D., Perricaudet, M., Jallat, S., Pavirani, A., Lecocq, J.-P. & Crystal, R. G. (1991) Science 252, 431-434.
12. Li, Q. T., Kay, M. A., Finegold, M., Stratford-Perricaudet, L. D. & Woo, S. L. C. (1993) Hum. Gene Ther. 4, 403-409.
13. Yang, Y., Ertl, H. C. J. & Wilson, J. M. (1994) Immunity 1, 433-442.
14. Barr, D., Tubb, J., Ferguson, D., Lieber, A., Perkins, A. J. & Kay, M. A. (1995) Gene Ther. 2, 151-155.
15. Malone, R. W., Hickman, M. A., Lehmann-Bruinsma, K., Sih, T. R., Walzem, R., Carlson, D. M. & Powell, J. S. (1994) J. Biol. Chem. 269, 29903-29907.
16. Hickman, M. A., Malone, R. W., Lehmann-Bruinsma, K., Sih, T. R., Knoell, D., Szoka, F. C., Walzem, R., Carlson, D. M. & Powell, J. S. (1994) Hum. Gene Ther. 5, 1477-1483.
17. Wu, G. Y. & Wu, C. H. (1988) J. Biol. Chem. 263, 14621-14624.
18. Wu, G. Y., Wilson, J. M., Shalaby, F., Grossman, M., Shafritz, D. A. & Wu, C. H. (1991) J. Biol. Chem. 266, 14338-14342.
19. Kaneda, A., Iwai, K. & Uchida, T. (1989) Science 243, 375-378.
20. Alino, S. F., Crespo, J., Bobadilla, M., Lejarreta, M., Blaya, C. & Crespo, A. (1994) Biochem. Biophys. Res. Commun. 204, 1023-1030.
21. Hara, T., Aramaki, Y., Takada, S., Koike, K. & Tsuchiya, S. (1995) Gene Ther. 2, 784-788.
22. Havel, R. J., Eder, H. A. & Bragdon, J. H. (1955) J. Clin. Chem. 34, 1345-1353.
23. Windler, E., Chao, Y.-S. & Havel, R. J. (1980) J. Biol. Chem. 255, 8303-8307.
24. Huettinger, M., Retzek, H., Eder, M. & Goldenberg, H. (1988) Clin. Biochem. 21, 87-92.
25. Mahley, R. W. & Hussain, M. M. (1991) Curr. Opin. Lipidol. 2, 170-176.
26. Rensen, P. C. N., Van Dijk, M. C. R., Havenaar, E. C., Bijsterbosch, M. K., Kruijt, J. K. & Van Berkel, T. J. C. (1995) Nat. Med. 1, 221-225.
27. Guo, Z. S., Wang, L. H., Eisensmith, R. C. & Woo, S. L. C. (1996) Gene Ther. 3, 802-810.
28. Kaplitt, M. G., Leon, P., Xiao, X., Samulski, R. J., Pfaff, D. W., O'Malley, K. L. & During, M. J. (1994) Nat. Genet. 8, 148-154.
29. Sambrook, J., Fritsch, E. F. & Maniatis, T. (1989) Molecular Cloning: A Laboratory Manual (Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY).
30. Gao, X. & Huang, L. (1991) Biochem. Biophys. Res. Commun. 179, 280-285.
31. Reimer, D. L., Zhang, Y.-P., Kong, S., Wheeler, J. J., Graham, R. W. & Bally, M. B. (1995) Biochemistry 34, 12877-12883.
32. Redgrave, T. G. & Maranhao, R. C. (1985) Biochim. Biophys. Acta 835, 104-112.
33. Kay, M. A., Graham, F., Leland, F. & Woo, S. L. C. (1995) Hepatology 21, 815-819.
34. Ruysschaert, J., El Ouahabi, A., Willeaume, V., Huez, G., Fuks, R., Vandenbranden, M. & Di Stefano, P. (1994) Biochem. Biophys. Res. Commun. 203, 1622-1628.
35. Wong, F. M. P., Reimer, D. L. & Bally, M. B. (1996) Biochemistry 35, 5756-5763.
36. Farhood, H., Serbina, N. & Huang, L. (1995) Biochim. Biophys. Acta 1235, 289-295.
37. Nabel, G. J., Nabel, E. G., Yang, Z. Y., Fox, B. A., Plautz, G. E., Gao, X., Huang, L., Shu, S., Gordon, D. & Chang, A. E. (1993) Proc. Natl. Acad. Sci. USA 90, 11307-11311.
38. Rose, J. K., Buonocore, L. & Whitt, M. A. (1991) BioTechniques 10, 520-525.
39. Budker, V., Zhang, G., Knechtle, S. & Wolff, J. A. (1996) Gene Ther. 3, 593-598.
40. Felgner, P. L., Gadek, P. R., Holm, M., Roman, R., Chan, H. W., Wenz, M., Northrop, J. P., Ringold, G. M. & Danielsen, M. (1987) Proc. Natl. Acad. Sci. USA 84, 7413-7417.
41. Koshizaka, T., Hayashi, Y. & Yagi, K. (1989) J. Clin. Biochem. Nutr. 7, 185-192.
42. Ito, A., Miyazoe, R., Mitoma, J., Akao, T., Osaki, T. & Kunitake, T. (1990) Biochem. Int. 22, 235-241.
43. Leventis, R. & Silvius, J. R. (1990) Biochim. Biophys. Acta 1023, 124-132.
44. Felgner, J. H., Kumar, R., Sridhar, C. N., Wheeler, C. J., Tsai, Y. J., Border, R., Ramsey, P., Martin, M. & Felgner, P. L. (1994) J. Biol. Chem. 269, 2550-2561.
45. Staedel, C., Remy, J., Hua, Z., Broker, T. R., Chow, L. T. & Behr, J. (1994) J. Invest. Dermatol. 102, 768-772.
46. Nabel, G. J., Chang, A. E., Nabel, E. G., Plautz, G. E., Ensminger, W., Fox, B. A., Felgner, F., Shu, S. & Cho, K. (1994) Hum. Gene Ther. 5, 57-77.
47. Porteous, D. J., Dorin, J. R., McLachlan, G., Davidson-Smith, H., Davidson, H., Stevenson, B. J., Carothers, A. D., Wallace, W. A. H., Moralee, S., Hoenes, C., Kallmeyer, G., Michaelis, U., Naujoks, K., Ho, L.-P., Samways, J. M., Imrie, M., Greening, A. P. & Innes, J. A. (1997) Gene Ther. 4, 210-218.
48. Nopanitaya, W., Lamb, J., Grisham, J. & Carson, J. (1976) Br. J. Exp. Pathol. 57, 604-609.
49. Hara, T., Aramaki, Y., Tsuchiya, S., Hosoi, K. & Okada, A. (1987) Biopharm. Drug Dispos. 8, 327-339.
50. Bijsterbosch, M. K., Ziere, G. J. & Van Berkel, T. J. C. (1989) Mol. Pharmacol. 36, 484-489.
51. Bijsterbosch, M. K., Schouten, D. & Van Berkel, T. J. C. (1994) Biochemistry 33, 14073-14080.
52. Okuyama, T., Huber, R. M., Bowling, W., Pearline, R., Kennedy, S. C., Flye, M. W. & Ponder, K. P. (1996) Hum. Gene Ther. 7, 637-645.
53. Marie-Jeanne, T. F. D., Peeters, V., Lieber, A., Perkins, J. & Kay, M. A. (1996) BioTechniques 20, 278-285.
54. Ilan, Y., Droguett, G., Chowdhury, N. R., Li, Y., Sengupta, K., Thummala, N. R., Davidson, A., Chowdhury, J. R. & Horwitz, M. S. (1997) Proc. Natl. Acad. Sci. USA 94, 2587-2592.
55. Ilan, Y., Parkash, R., Davidson, A., Jona, V., Droguett, G., Horwitz, M. S., Chowdhury, N. R. & Chowdhury, J. R. (1997) J. Clin. Invest. 99, 1098-1106.
56. McKeon, C. & Samulski, R. J. (1996) Hum. Gene Ther. 7, 1615-1619.
57. Koeberl, D. D., Alexander, I. E., Halbert, C. L., Russell, D. W. & Miller, A. D. (1997) Proc. Natl. Acad. Sci. USA 94, 1426-1431.
58. Marie-Jeanne, T. F. D., Peeters, V., Patijn, G. A., Lieber, A., Meuse, L. & Kay, M. A. (1996) Hum. Gene Ther. 7, 1693-1699.