Celastrol inhibits Plasmodium falciparum enoyl-acyl carrier protein reductase

Bioorganic and Medicinal Chemistry

Volumn 22, Issue 21, 2014, Pages 6053-6061

  Tallorin, Lorillee ^a   Durrant, Jacob D ^a,b   Nguyen, Quynh G ^a   McCammon, J Andrew ^a,b,c,d   Burkart, Michael D ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c San Diego   (United States)

^d HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

Celastrol; Enoyl acyl carrier protein reductase in silico; Malaria; Plasmodium falciparum

Indexed keywords

CELASTROL; ENOYL ACYL CARRIER PROTEIN REDUCTASE (NADH); ANTIMALARIAL AGENT; TRIPTERINE; TRITERPENE;

ARTICLE; BACTERIUM IDENTIFICATION; DRUG DETERMINATION; DRUG SCREENING; DRUG STRUCTURE; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME INHIBITION; ENZYME STRUCTURE; FOOD AND DRUG ADMINISTRATION; IN VITRO STUDY; PLASMODIUM FALCIPARUM; VALIDATION PROCESS; ANTAGONISTS AND INHIBITORS; CHEMISTRY; DRUG EFFECTS; ENZYMOLOGY; HUMAN; MALARIA, FALCIPARUM; METABOLISM; MICROBIOLOGY; MOLECULAR DOCKING;

ANTIMALARIALS; ENOYL-(ACYL-CARRIER-PROTEIN) REDUCTASE (NADH); HUMANS; MALARIA, FALCIPARUM; MOLECULAR DOCKING SIMULATION; PLASMODIUM FALCIPARUM; TRITERPENES;

EID: 84908432141     PISSN: 09680896     EISSN: 14643391     Source Type: Journal    
DOI: 10.1016/j.bmc.2014.09.002     Document Type: Article

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