Non-competitive inhibition by active site binders

Chemical Biology and Drug Design

Volumn 75, Issue 6, 2010, Pages 535-540

  Blat, Yuval ^a  

^a BRISTOL MYERS SQUIBB   (United States)

Author keywords

Active site; Competitive inhibition; Enzymes; Non competitive inhibition; Reaction mechanism

Indexed keywords

BETA SECRETASE; BLOOD CLOTTING FACTOR 10A; PROTEIN KINASE; SERINE PROTEINASE;

BINDING AFFINITY; BINDING SITE; COMPETITIVE INHIBITION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME BINDING; ENZYME INHIBITION; ENZYME INHIBITOR INTERACTION; ENZYME MECHANISM; ENZYME STABILITY; ENZYME SUBSTRATE; ENZYME SUBSTRATE COMPLEX; EXPERIMENTAL DESIGN; MOLECULAR WEIGHT; NONCOMPETITIVE INHIBITION; PRIORITY JOURNAL; REVIEW;

BINDING, COMPETITIVE; CATALYTIC DOMAIN; ENZYME INHIBITORS; ENZYMES;

EID: 77951953170     PISSN: 17470277     EISSN: 17470285     Source Type: Journal    
DOI: 10.1111/j.1747-0285.2010.00972.x     Document Type: Review

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