-
1
-
-
84871090162
-
Global obesity: trends, risk factors and policy implications
-
Malik V.S., Willett W.C., Hu F.B. Global obesity: trends, risk factors and policy implications. Nat. Rev. Endocrinol. 2013, 9:13-27.
-
(2013)
Nat. Rev. Endocrinol.
, vol.9
, pp. 13-27
-
-
Malik, V.S.1
Willett, W.C.2
Hu, F.B.3
-
2
-
-
84858077267
-
The medical care costs of obesity: an instrumental variables approach
-
Cawley J., Meyerhoefer C. The medical care costs of obesity: an instrumental variables approach. J. Health Econ. 2012, 31:219-230.
-
(2012)
J. Health Econ.
, vol.31
, pp. 219-230
-
-
Cawley, J.1
Meyerhoefer, C.2
-
3
-
-
70349207410
-
Annual medical spending attributable to obesity: payer-and service-specific estimates
-
Finkelstein E.A., Trogdon J.G., Cohen J.W., Dietz W. Annual medical spending attributable to obesity: payer-and service-specific estimates. Health Aff. (Millwood) 2009, 28:w822-w831.
-
(2009)
Health Aff. (Millwood)
, vol.28
, pp. w822-w831
-
-
Finkelstein, E.A.1
Trogdon, J.G.2
Cohen, J.W.3
Dietz, W.4
-
4
-
-
33845567553
-
Genetics of obesity in humans
-
Farooqi I.S., O'Rahilly S. Genetics of obesity in humans. Endocr. Rev. 2006, 27:710-718.
-
(2006)
Endocr. Rev.
, vol.27
, pp. 710-718
-
-
Farooqi, I.S.1
O'Rahilly, S.2
-
5
-
-
34547654219
-
The global epidemic of obesity: an overview
-
Caballero B. The global epidemic of obesity: an overview. Epidemiol. Rev. 2007, 29:1-5.
-
(2007)
Epidemiol. Rev.
, vol.29
, pp. 1-5
-
-
Caballero, B.1
-
6
-
-
84859575363
-
Genetic determinants of common obesity and their value in prediction
-
Loos R.J.F. Genetic determinants of common obesity and their value in prediction. Best Pract. Res. Clin. Endocrinol. Metab. 2012, 26:211-226.
-
(2012)
Best Pract. Res. Clin. Endocrinol. Metab.
, vol.26
, pp. 211-226
-
-
Loos, R.J.F.1
-
7
-
-
58149163142
-
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation
-
Willer C.J., Speliotes E.K., Loos R.J.F., Li S., Lindgren C.M., Heid I.M., Berndt S.I., Elliott A.L., Jackson A.U., Lamina C., Lettre G., Lim N., Lyon H.N., McCarroll S.A., Papadakis K., Qi L., Randall J.C., Roccasecca R.M., Sanna S., Scheet P., et al. Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nat. Genet. 2009, 41:25-34.
-
(2009)
Nat. Genet.
, vol.41
, pp. 25-34
-
-
Willer, C.J.1
Speliotes, E.K.2
Loos, R.J.F.3
Li, S.4
Lindgren, C.M.5
Heid, I.M.6
Berndt, S.I.7
Elliott, A.L.8
Jackson, A.U.9
Lamina, C.10
Lettre, G.11
Lim, N.12
Lyon, H.N.13
McCarroll, S.A.14
Papadakis, K.15
Qi, L.16
Randall, J.C.17
Roccasecca, R.M.18
Sanna, S.19
Scheet, P.20
more..
-
8
-
-
34249777814
-
Variation in FTO contributes to childhood obesity and severe adult obesity
-
Dina C., Meyre D., Gallina S., Durand E., Körner A., Jacobson P., Carlsson L.M.S., Kiess W., Vatin V., Lecoeur C., Delplanque J., Vaillant E., Pattou F., Ruiz J., Weill J., Levy-Marchal C., Horber F., Potoczna N., Hercberg S., Le Stunff C., et al. Variation in FTO contributes to childhood obesity and severe adult obesity. Nat. Genet. 2007, 39:724-726.
-
(2007)
Nat. Genet.
, vol.39
, pp. 724-726
-
-
Dina, C.1
Meyre, D.2
Gallina, S.3
Durand, E.4
Körner, A.5
Jacobson, P.6
Carlsson, L.M.S.7
Kiess, W.8
Vatin, V.9
Lecoeur, C.10
Delplanque, J.11
Vaillant, E.12
Pattou, F.13
Ruiz, J.14
Weill, J.15
Levy-Marchal, C.16
Horber, F.17
Potoczna, N.18
Hercberg, S.19
Le Stunff, C.20
more..
-
9
-
-
34547625955
-
Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits
-
Scuteri A., Sanna S., Chen W.-M., Uda M., Albai G., Strait J., Najjar S., Nagaraja R., Orrú M., Usala G., Dei M., Lai S., Maschio A., Busonero F., Mulas A., Ehret G.B., Fink A.A., Weder A.B., Cooper R.S., Galan P., et al. Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits. PLoS Genet. 2007, 3:e115.
-
(2007)
PLoS Genet.
, vol.3
, pp. e115
-
-
Scuteri, A.1
Sanna, S.2
Chen, W.-M.3
Uda, M.4
Albai, G.5
Strait, J.6
Najjar, S.7
Nagaraja, R.8
Orrú, M.9
Usala, G.10
Dei, M.11
Lai, S.12
Maschio, A.13
Busonero, F.14
Mulas, A.15
Ehret, G.B.16
Fink, A.A.17
Weder, A.B.18
Cooper, R.S.19
Galan, P.20
more..
-
10
-
-
34248594090
-
A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity
-
Frayling T.M., Timpson N.J., Weedon M.N., Zeggini E., Freathy R.M., Lindgren C.M., Perry J.R.B., Elliott K.S., Lango H., Rayner N.W., Shields B., Harries L.W., Barrett J.C., Ellard S., Groves C.J., Knight B., Patch A.-M., Ness A.R., Ebrahim S., Lawlor D.A., et al. A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. Science 2007, 316:889-894.
-
(2007)
Science
, vol.316
, pp. 889-894
-
-
Frayling, T.M.1
Timpson, N.J.2
Weedon, M.N.3
Zeggini, E.4
Freathy, R.M.5
Lindgren, C.M.6
Perry, J.R.B.7
Elliott, K.S.8
Lango, H.9
Rayner, N.W.10
Shields, B.11
Harries, L.W.12
Barrett, J.C.13
Ellard, S.14
Groves, C.J.15
Knight, B.16
Patch, A.-M.17
Ness, A.R.18
Ebrahim, S.19
Lawlor, D.A.20
more..
-
11
-
-
0032886705
-
Cloning of Fatso (Fto), a novel gene deleted by the Fused toes (Ft) mouse mutation
-
Peters T., Ausmeier K., Rüther U. Cloning of Fatso (Fto), a novel gene deleted by the Fused toes (Ft) mouse mutation. Mamm. Genome 1999, 10:983-986.
-
(1999)
Mamm. Genome
, vol.10
, pp. 983-986
-
-
Peters, T.1
Ausmeier, K.2
Rüther, U.3
-
12
-
-
0028025622
-
Programmed cell death is affected in the novel mouse mutant Fused toes (Ft)
-
van der Hoeven F., Schimmang T., Volkmann A., Mattei M.G., Kyewski B., Rüther U. Programmed cell death is affected in the novel mouse mutant Fused toes (Ft). Development 1994, 120:2601-2607.
-
(1994)
Development
, vol.120
, pp. 2601-2607
-
-
van der Hoeven, F.1
Schimmang, T.2
Volkmann, A.3
Mattei, M.G.4
Kyewski, B.5
Rüther, U.6
-
13
-
-
84868545869
-
The impact of intronic single nucleotide polymorphisms and ethnic diversity for studies on the obesity gene FTO
-
Jacobsson J.A., Schiöth H.B., Fredriksson R. The impact of intronic single nucleotide polymorphisms and ethnic diversity for studies on the obesity gene FTO. Obes. Rev. 2012, 13:1096-1109.
-
(2012)
Obes. Rev.
, vol.13
, pp. 1096-1109
-
-
Jacobsson, J.A.1
Schiöth, H.B.2
Fredriksson, R.3
-
14
-
-
79952262429
-
Association between common variation at the FTO locus and changes in body mass index from infancy to late childhood: the complex nature of genetic association through growth and development
-
Sovio U., Mook-Kanamori D.O., Warrington N.M., Lawrence R., Briollais L., Palmer C.N.A., Cecil J., Sandling J.K., Syvänen A.-C., Kaakinen M., Beilin L.J., Millwood I.Y., Bennett A.J., Laitinen J., Pouta A., Molitor J., Davey Smith G., Ben-Shlomo Y., Jaddoe V.W.V., Palmer L.J., et al. Association between common variation at the FTO locus and changes in body mass index from infancy to late childhood: the complex nature of genetic association through growth and development. PLoS Genet. 2011, 7:e1001307.
-
(2011)
PLoS Genet.
, vol.7
, pp. e1001307
-
-
Sovio, U.1
Mook-Kanamori, D.O.2
Warrington, N.M.3
Lawrence, R.4
Briollais, L.5
Palmer, C.N.A.6
Cecil, J.7
Sandling, J.K.8
Syvänen, A.-C.9
Kaakinen, M.10
Beilin, L.J.11
Millwood, I.Y.12
Bennett, A.J.13
Laitinen, J.14
Pouta, A.15
Molitor, J.16
Davey Smith, G.17
Ben-Shlomo, Y.18
Jaddoe, V.W.V.19
Palmer, L.J.20
more..
-
15
-
-
79951867607
-
The obesity related gene, FTO, interacts with APOE, and is associated with Alzheimer's disease risk: a prospective cohort study
-
Keller L., Xu W., Wang H.-X., Winblad B., Fratiglioni L., Graff C. The obesity related gene, FTO, interacts with APOE, and is associated with Alzheimer's disease risk: a prospective cohort study. J. Alzheimers Dis. 2011, 23:461-469.
-
(2011)
J. Alzheimers Dis.
, vol.23
, pp. 461-469
-
-
Keller, L.1
Xu, W.2
Wang, H.-X.3
Winblad, B.4
Fratiglioni, L.5
Graff, C.6
-
16
-
-
57749121512
-
An obesity-associated FTO gene variant and increased energy intake in children
-
Cecil J.E., Tavendale R., Watt P., Hetherington M.M., Palmer C.N.A. An obesity-associated FTO gene variant and increased energy intake in children. N. Engl. J. Med. 2008, 359:2558-2566.
-
(2008)
N. Engl. J. Med.
, vol.359
, pp. 2558-2566
-
-
Cecil, J.E.1
Tavendale, R.2
Watt, P.3
Hetherington, M.M.4
Palmer, C.N.A.5
-
17
-
-
67649852402
-
Variation in the FTO gene influences food intake but not energy expenditure
-
Haupt A., Thamer C., Staiger H., Tschritter O., Kirchhoff K., Machicao F., Häring H.-U., Stefan N., Fritsche A. Variation in the FTO gene influences food intake but not energy expenditure. Exp. Clin. Endocrinol. Diabetes 2009, 117:194-197.
-
(2009)
Exp. Clin. Endocrinol. Diabetes
, vol.117
, pp. 194-197
-
-
Haupt, A.1
Thamer, C.2
Staiger, H.3
Tschritter, O.4
Kirchhoff, K.5
Machicao, F.6
Häring, H.-U.7
Stefan, N.8
Fritsche, A.9
-
18
-
-
48749132799
-
Polymorphisms of the FTO gene are associated with variation in energy intake, but not energy expenditure
-
Speakman J.R., Rance K.A., Johnstone A.M. Polymorphisms of the FTO gene are associated with variation in energy intake, but not energy expenditure. Obesity 2008, 16:1961-1965.
-
(2008)
Obesity
, vol.16
, pp. 1961-1965
-
-
Speakman, J.R.1
Rance, K.A.2
Johnstone, A.M.3
-
19
-
-
53849088890
-
The fat mass- and obesity-associated locus and dietary intake in children
-
Timpson N.J., Emmett P.M., Frayling T.M., Rogers I., Hattersley A.T., McCarthy M.I., Smith G.D. The fat mass- and obesity-associated locus and dietary intake in children. Am. J. Clin. Nutr. 2008, 88:971-978.
-
(2008)
Am. J. Clin. Nutr.
, vol.88
, pp. 971-978
-
-
Timpson, N.J.1
Emmett, P.M.2
Frayling, T.M.3
Rogers, I.4
Hattersley, A.T.5
McCarthy, M.I.6
Smith, G.D.7
-
20
-
-
58149508094
-
The FTO gene and measured food intake in children
-
Wardle J., Llewellyn C., Sanderson S., Plomin R. The FTO gene and measured food intake in children. Int. J. Obes. (Lond.) 2009, 33:42-45.
-
(2009)
Int. J. Obes. (Lond.)
, vol.33
, pp. 42-45
-
-
Wardle, J.1
Llewellyn, C.2
Sanderson, S.3
Plomin, R.4
-
21
-
-
72749115949
-
The FTO gene rs9939609 obesity-risk allele and loss of control over eating
-
Tanofsky-Kraff M., Han J.C., Anandalingam K., Shomaker L.B., Columbo K.M., Wolkoff L.E., Kozlosky M., Elliott C., Ranzenhofer L.M., Roza C.A., Yanovski S.Z., Yanovski J.A. The FTO gene rs9939609 obesity-risk allele and loss of control over eating. Am. J. Clin. Nutr. 2009, 90:1483-1488.
-
(2009)
Am. J. Clin. Nutr.
, vol.90
, pp. 1483-1488
-
-
Tanofsky-Kraff, M.1
Han, J.C.2
Anandalingam, K.3
Shomaker, L.B.4
Columbo, K.M.5
Wolkoff, L.E.6
Kozlosky, M.7
Elliott, C.8
Ranzenhofer, L.M.9
Roza, C.A.10
Yanovski, S.Z.11
Yanovski, J.A.12
-
22
-
-
51649128621
-
Obesity associated genetic variation in FTO is associated with diminished satiety
-
Wardle J., Carnell S., Haworth C.M.A., Farooqi I.S., O'Rahilly S., Plomin R. Obesity associated genetic variation in FTO is associated with diminished satiety. J. Clin. Endocrinol. Metab. 2008, 93:3640-3643.
-
(2008)
J. Clin. Endocrinol. Metab.
, vol.93
, pp. 3640-3643
-
-
Wardle, J.1
Carnell, S.2
Haworth, C.M.A.3
Farooqi, I.S.4
O'Rahilly, S.5
Plomin, R.6
-
23
-
-
84869102944
-
FTO at rs9939609, food responsiveness, emotional control and symptoms of ADHD in preschool children
-
Velders F.P., De Wit J.E., Jansen P.W., Jaddoe V.W.V., Hofman A., Verhulst F.C., Tiemeier H. FTO at rs9939609, food responsiveness, emotional control and symptoms of ADHD in preschool children. PLoS ONE 2012, 7:e49131.
-
(2012)
PLoS ONE
, vol.7
, pp. e49131
-
-
Velders, F.P.1
De Wit, J.E.2
Jansen, P.W.3
Jaddoe, V.W.V.4
Hofman, A.5
Verhulst, F.C.6
Tiemeier, H.7
-
24
-
-
70350647201
-
Postprandial responses in hunger and satiety are associated with the rs9939609 single nucleotide polymorphism in FTO
-
den Hoed M., Westerterp-Plantenga M.S., Bouwman F.G., Mariman E.C.M., Westerterp K.R. Postprandial responses in hunger and satiety are associated with the rs9939609 single nucleotide polymorphism in FTO. Am. J. Clin. Nutr. 2009, 90:1426-1432.
-
(2009)
Am. J. Clin. Nutr.
, vol.90
, pp. 1426-1432
-
-
den Hoed, M.1
Westerterp-Plantenga, M.S.2
Bouwman, F.G.3
Mariman, E.C.M.4
Westerterp, K.R.5
-
25
-
-
84881257670
-
A link between FTO, ghrelin, and impaired brain food-cue responsivity
-
Karra E., O'Daly O.G., Choudhury A.I., Yousseif A., Millership S., Neary M.T., Scott W.R., Chandarana K., Manning S., Hess M.E., Iwakura H., Akamizu T., Millet Q., Gelegen C., Drew M.E., Rahman S., Emmanuel J.J., Williams S.C.R., Rüther U.U., Brüning J.C., et al. A link between FTO, ghrelin, and impaired brain food-cue responsivity. J. Clin. Invest. 2013, 123:3539-3551.
-
(2013)
J. Clin. Invest.
, vol.123
, pp. 3539-3551
-
-
Karra, E.1
O'Daly, O.G.2
Choudhury, A.I.3
Yousseif, A.4
Millership, S.5
Neary, M.T.6
Scott, W.R.7
Chandarana, K.8
Manning, S.9
Hess, M.E.10
Iwakura, H.11
Akamizu, T.12
Millet, Q.13
Gelegen, C.14
Drew, M.E.15
Rahman, S.16
Emmanuel, J.J.17
Williams, S.C.R.18
Rüther, U.U.19
Brüning, J.C.20
more..
-
26
-
-
64349124477
-
Obesity FTO gene variant, and energy intake in children
-
(author reply 1572)
-
Jonsson A., Franks P.W. Obesity FTO gene variant, and energy intake in children. N. Engl. J. Med. 2009, 360:1571-1572. (author reply 1572).
-
(2009)
N. Engl. J. Med.
, vol.360
, pp. 1571-1572
-
-
Jonsson, A.1
Franks, P.W.2
-
27
-
-
65249108267
-
FTO genotype is associated with body mass index after the age of seven years but not with energy intake or leisure-time physical activity
-
Hakanen M., Raitakari O.T., Lehtimäki T., Peltonen N., Pahkala K., Sillanmäki L., Lagström H., Viikari J., Simell O., Rönnemaa T. FTO genotype is associated with body mass index after the age of seven years but not with energy intake or leisure-time physical activity. J. Clin. Endocrinol. Metab. 2009, 94:1281-1287.
-
(2009)
J. Clin. Endocrinol. Metab.
, vol.94
, pp. 1281-1287
-
-
Hakanen, M.1
Raitakari, O.T.2
Lehtimäki, T.3
Peltonen, N.4
Pahkala, K.5
Sillanmäki, L.6
Lagström, H.7
Viikari, J.8
Simell, O.9
Rönnemaa, T.10
-
28
-
-
67449141659
-
NUGENOB consortium, several obesity- and nutrient-related gene polymorphisms but not FTO and UCP variants modulate postabsorptive resting energy expenditure and fat-induced thermogenesis in obese individuals: the NUGENOB study
-
Goossens G.H., Petersen L., Blaak E.E., Hul G., Arner P., Astrup A., Froguel P., Patel K., Pedersen O., Polak J., Oppert J.-M., Martinez J.A., Sørensen T.I.A., Saris W.H.M. NUGENOB consortium, several obesity- and nutrient-related gene polymorphisms but not FTO and UCP variants modulate postabsorptive resting energy expenditure and fat-induced thermogenesis in obese individuals: the NUGENOB study. Int. J. Obes. (Lond.) 2009, 33:669-679.
-
(2009)
Int. J. Obes. (Lond.)
, vol.33
, pp. 669-679
-
-
Goossens, G.H.1
Petersen, L.2
Blaak, E.E.3
Hul, G.4
Arner, P.5
Astrup, A.6
Froguel, P.7
Patel, K.8
Pedersen, O.9
Polak, J.10
Oppert, J.-M.11
Martinez, J.A.12
Sørensen, T.I.A.13
Saris, W.H.M.14
-
29
-
-
47549107452
-
Lack of association of fatness-related FTO gene variants with energy expenditure or physical activity
-
Berentzen T., Kring S.I.I., Holst C., Zimmermann E., Jess T., Hansen T., Pedersen O., Toubro S., Astrup A., Sørensen T.I.A. Lack of association of fatness-related FTO gene variants with energy expenditure or physical activity. J. Clin. Endocrinol. Metab. 2008, 93:2904-2908.
-
(2008)
J. Clin. Endocrinol. Metab.
, vol.93
, pp. 2904-2908
-
-
Berentzen, T.1
Kring, S.I.I.2
Holst, C.3
Zimmermann, E.4
Jess, T.5
Hansen, T.6
Pedersen, O.7
Toubro, S.8
Astrup, A.9
Sørensen, T.I.A.10
-
30
-
-
67949120377
-
Physical activity attenuates the body mass index-increasing influence of genetic variation in the FTO gene
-
Vimaleswaran K.S., Li S., Zhao J.H., Luan J., Bingham S.A., Khaw K.-T., Ekelund U., Wareham N.J., Loos R.J.F. Physical activity attenuates the body mass index-increasing influence of genetic variation in the FTO gene. Am. J. Clin. Nutr. 2009, 90:425-428.
-
(2009)
Am. J. Clin. Nutr.
, vol.90
, pp. 425-428
-
-
Vimaleswaran, K.S.1
Li, S.2
Zhao, J.H.3
Luan, J.4
Bingham, S.A.5
Khaw, K.-T.6
Ekelund, U.7
Wareham, N.J.8
Loos, R.J.F.9
-
31
-
-
41749092048
-
Regulation of Fto/Ftm gene expression in mice and humans
-
Stratigopoulos G., Padilla S.L., Leduc C.A., Watson E., Hattersley A.T., McCarthy M.I., Zeltser L.M., Chung W.K., Leibel R.L. Regulation of Fto/Ftm gene expression in mice and humans. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2008, 294:R1185-R1196.
-
(2008)
Am. J. Physiol. Regul. Integr. Comp. Physiol.
, vol.294
, pp. R1185-R1196
-
-
Stratigopoulos, G.1
Padilla, S.L.2
Leduc, C.A.3
Watson, E.4
Hattersley, A.T.5
McCarthy, M.I.6
Zeltser, L.M.7
Chung, W.K.8
Leibel, R.L.9
-
32
-
-
78649464259
-
Cut-like homeobox 1 (CUX1) regulates expression of the fat mass and obesity-associated and retinitis pigmentosa GTPase regulator-interacting protein-1-like (RPGRIP1L) genes and coordinates leptin receptor signaling
-
Stratigopoulos G., Leduc C.A., Cremona M.L., Chung W.K., Leibel R.L. Cut-like homeobox 1 (CUX1) regulates expression of the fat mass and obesity-associated and retinitis pigmentosa GTPase regulator-interacting protein-1-like (RPGRIP1L) genes and coordinates leptin receptor signaling. J. Biol. Chem. 2011, 286:2155-2170.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 2155-2170
-
-
Stratigopoulos, G.1
Leduc, C.A.2
Cremona, M.L.3
Chung, W.K.4
Leibel, R.L.5
-
33
-
-
34547800833
-
Ftm is a novel basal body protein of cilia involved in Shh signalling
-
Vierkotten J., Dildrop R., Peters T., Wang B., Rüther U. Ftm is a novel basal body protein of cilia involved in Shh signalling. Development 2007, 134:2569-2577.
-
(2007)
Development
, vol.134
, pp. 2569-2577
-
-
Vierkotten, J.1
Dildrop, R.2
Peters, T.3
Wang, B.4
Rüther, U.5
-
34
-
-
34347324031
-
The ciliary gene RPGRIP1L is mutated in cerebello-oculo-renal syndrome (Joubert syndrome type B) and Meckel syndrome
-
Delous M., Baala L., Salomon R., Laclef C., Vierkotten J., Tory K., Golzio C., Lacoste T., Besse L., Ozilou C., Moutkine I., Hellman N.E., Anselme I., Silbermann F., Vesque C., Gerhardt C., Rattenberry E., Wolf M.T.F., Gubler M.C., Martinovic J., et al. The ciliary gene RPGRIP1L is mutated in cerebello-oculo-renal syndrome (Joubert syndrome type B) and Meckel syndrome. Nat. Genet. 2007, 39:875-881.
-
(2007)
Nat. Genet.
, vol.39
, pp. 875-881
-
-
Delous, M.1
Baala, L.2
Salomon, R.3
Laclef, C.4
Vierkotten, J.5
Tory, K.6
Golzio, C.7
Lacoste, T.8
Besse, L.9
Ozilou, C.10
Moutkine, I.11
Hellman, N.E.12
Anselme, I.13
Silbermann, F.14
Vesque, C.15
Gerhardt, C.16
Rattenberry, E.17
Wolf, M.T.F.18
Gubler, M.C.19
Martinovic, J.20
more..
-
35
-
-
84877313950
-
Leptin resistance is a secondary consequence of the obesity in ciliopathy mutant mice
-
Berbari N.F., Pasek R.C., Malarkey E.B., Yazdi S.M.Z., McNair A.D., Lewis W.R., Nagy T.R., Kesterson R.A., Yoder B.K. Leptin resistance is a secondary consequence of the obesity in ciliopathy mutant mice. Proc. Natl. Acad. Sci. 2013, 110:7796-7801.
-
(2013)
Proc. Natl. Acad. Sci.
, vol.110
, pp. 7796-7801
-
-
Berbari, N.F.1
Pasek, R.C.2
Malarkey, E.B.3
Yazdi, S.M.Z.4
McNair, A.D.5
Lewis, W.R.6
Nagy, T.R.7
Kesterson, R.A.8
Yoder, B.K.9
-
36
-
-
84870761696
-
A truncating mutation of Alms1 reduces the number of hypothalamic neuronal cilia in obese mice
-
Heydet D., Chen L.X., Larter C.Z., Inglis C., Silverman M.A., Farrell G.C., Leroux M.R. A truncating mutation of Alms1 reduces the number of hypothalamic neuronal cilia in obese mice. Dev. Neurobiol. 2013, 73:1-13.
-
(2013)
Dev. Neurobiol.
, vol.73
, pp. 1-13
-
-
Heydet, D.1
Chen, L.X.2
Larter, C.Z.3
Inglis, C.4
Silverman, M.A.5
Farrell, G.C.6
Leroux, M.R.7
-
37
-
-
79451474853
-
Alström syndrome: insights into the pathogenesis of metabolic disorders
-
Girard D., Petrovsky N. Alström syndrome: insights into the pathogenesis of metabolic disorders. Nat. Rev. Endocrinol. 2011, 7:77-88.
-
(2011)
Nat. Rev. Endocrinol.
, vol.7
, pp. 77-88
-
-
Girard, D.1
Petrovsky, N.2
-
38
-
-
0142104970
-
Basal body dysfunction is a likely cause of pleiotropic Bardet-Biedl syndrome
-
Ansley S.J., Badano J.L., Blacque O.E., Hill J., Hoskins B.E., Leitch C.C., Kim J.C., Ross A.J., Eichers E.R., Teslovich T.M., Mah A.K., Johnsen R.C., Cavender J.C., Lewis R.A., Leroux M.R., Beales P.L., Katsanis N. Basal body dysfunction is a likely cause of pleiotropic Bardet-Biedl syndrome. Nature 2003, 425:628-633.
-
(2003)
Nature
, vol.425
, pp. 628-633
-
-
Ansley, S.J.1
Badano, J.L.2
Blacque, O.E.3
Hill, J.4
Hoskins, B.E.5
Leitch, C.C.6
Kim, J.C.7
Ross, A.J.8
Eichers, E.R.9
Teslovich, T.M.10
Mah, A.K.11
Johnsen, R.C.12
Cavender, J.C.13
Lewis, R.A.14
Leroux, M.R.15
Beales, P.L.16
Katsanis, N.17
-
39
-
-
34548490748
-
Disruption of intraflagellar transport in adult mice leads to obesity and slow-onset cystic kidney disease
-
Davenport J.R., Watts A.J., Roper V.C., Croyle M.J., van Groen T., Wyss J.M., Nagy T.R., Kesterson R.A., Yoder B.K. Disruption of intraflagellar transport in adult mice leads to obesity and slow-onset cystic kidney disease. Curr. Biol. 2007, 17:1586-1594.
-
(2007)
Curr. Biol.
, vol.17
, pp. 1586-1594
-
-
Davenport, J.R.1
Watts, A.J.2
Roper, V.C.3
Croyle, M.J.4
van Groen, T.5
Wyss, J.M.6
Nagy, T.R.7
Kesterson, R.A.8
Yoder, B.K.9
-
40
-
-
44449116559
-
Mutations in RPGRIP1L: extending the clinical spectrum of ciliopathies
-
Devuyst O., Arnould V.J. Mutations in RPGRIP1L: extending the clinical spectrum of ciliopathies. Nephrol. Dial. Transplant. 2008, 23:1500-1503.
-
(2008)
Nephrol. Dial. Transplant.
, vol.23
, pp. 1500-1503
-
-
Devuyst, O.1
Arnould, V.J.2
-
41
-
-
79952305733
-
Inverse association of the obesity predisposing FTO rs9939609 genotype with alcohol consumption and risk for alcohol dependence
-
Sobczyk-Kopciol A., Broda G., Wojnar M., Kurjata P., Jakubczyk A., Klimkiewicz A., Ploski R. Inverse association of the obesity predisposing FTO rs9939609 genotype with alcohol consumption and risk for alcohol dependence. Addiction 2011, 106:739-748.
-
(2011)
Addiction
, vol.106
, pp. 739-748
-
-
Sobczyk-Kopciol, A.1
Broda, G.2
Wojnar, M.3
Kurjata, P.4
Jakubczyk, A.5
Klimkiewicz, A.6
Ploski, R.7
-
42
-
-
36749041363
-
The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase
-
Gerken T., Girard C.A., Tung Y.-C.L., Webby C.J., Saudek V., Hewitson K.S., Yeo G.S.H., McDonough M.A., Cunliffe S., McNeill L.A., Galvanovskis J., Rorsman P., Robins P., Prieur X., Coll A.P., Ma M., Jovanovic Z., Farooqi I.S., Sedgwick B., Barroso I., et al. The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase. Science 2007, 318:1469-1472.
-
(2007)
Science
, vol.318
, pp. 1469-1472
-
-
Gerken, T.1
Girard, C.A.2
Tung, Y.-C.L.3
Webby, C.J.4
Saudek, V.5
Hewitson, K.S.6
Yeo, G.S.H.7
McDonough, M.A.8
Cunliffe, S.9
McNeill, L.A.10
Galvanovskis, J.11
Rorsman, P.12
Robins, P.13
Prieur, X.14
Coll, A.P.15
Ma, M.16
Jovanovic, Z.17
Farooqi, I.S.18
Sedgwick, B.19
Barroso, I.20
more..
-
43
-
-
84889632492
-
Association between obesity-related gene FTO and ADHD
-
Choudhry Z., Sengupta S.M., Grizenko N., Thakur G.A., Fortier M.-E., Schmitz N., Joober R. Association between obesity-related gene FTO and ADHD. Obesity 2013, 21(12):E738-E744.
-
(2013)
Obesity
, vol.21
, Issue.12
, pp. E738-E744
-
-
Choudhry, Z.1
Sengupta, S.M.2
Grizenko, N.3
Thakur, G.A.4
Fortier, M.-E.5
Schmitz, N.6
Joober, R.7
-
44
-
-
48249135775
-
Overweight in children and adolescents in relation to attention-deficit/hyperactivity disorder: results from a national sample
-
Waring M.E., Waring M.E., Lapane K.L., Lapane K.L. Overweight in children and adolescents in relation to attention-deficit/hyperactivity disorder: results from a national sample. Pediatrics 2008, 122:e1-e6.
-
(2008)
Pediatrics
, vol.122
, pp. e1-e6
-
-
Waring, M.E.1
Waring, M.E.2
Lapane, K.L.3
Lapane, K.L.4
-
45
-
-
84861427419
-
Depressive disorder moderates the effect of the FTO gene on body mass index
-
Rivera M., Cohen-Woods S., Kapur K., Breen G., Ng M.Y., Butler A.W., Craddock N., Gill M., Korszun A., Maier W., Mors O., Owen M.J., Preisig M., Bergmann S., Tozzi F., Rice J., Rietschel M., Rucker J., Schosser A., Aitchison K.J., et al. Depressive disorder moderates the effect of the FTO gene on body mass index. Mol. Psychiatry 2012, 17:604-611.
-
(2012)
Mol. Psychiatry
, vol.17
, pp. 604-611
-
-
Rivera, M.1
Cohen-Woods, S.2
Kapur, K.3
Breen, G.4
Ng, M.Y.5
Butler, A.W.6
Craddock, N.7
Gill, M.8
Korszun, A.9
Maier, W.10
Mors, O.11
Owen, M.J.12
Preisig, M.13
Bergmann, S.14
Tozzi, F.15
Rice, J.16
Rietschel, M.17
Rucker, J.18
Schosser, A.19
Aitchison, K.J.20
more..
-
46
-
-
84888286267
-
The protective effect of the obesity-associated rs9939609 a variant in fat mass- and obesity-associated gene on depression
-
Samaan Z., Anand S., Zhang X., Desai D., Rivera M., Pare G., Thabane L., Xie C., Gerstein H., Engert J.C., Craig I., Cohen-Woods S., Mohan V., Diaz R., Wang X., Liu L., Corre T., Preisig M., Kutalik Z., Bergmann S., et al. The protective effect of the obesity-associated rs9939609 a variant in fat mass- and obesity-associated gene on depression. Mol. Psychiatry 2013, 18:1281-1286.
-
(2013)
Mol. Psychiatry
, vol.18
, pp. 1281-1286
-
-
Samaan, Z.1
Anand, S.2
Zhang, X.3
Desai, D.4
Rivera, M.5
Pare, G.6
Thabane, L.7
Xie, C.8
Gerstein, H.9
Engert, J.C.10
Craig, I.11
Cohen-Woods, S.12
Mohan, V.13
Diaz, R.14
Wang, X.15
Liu, L.16
Corre, T.17
Preisig, M.18
Kutalik, Z.19
Bergmann, S.20
more..
-
47
-
-
0035023919
-
The association between childhood depression and adulthood body mass index
-
Pine D.S., Goldstein R.B., Wolk S., Weissman M.M. The association between childhood depression and adulthood body mass index. Pediatrics 2001, 107:1049-1056.
-
(2001)
Pediatrics
, vol.107
, pp. 1049-1056
-
-
Pine, D.S.1
Goldstein, R.B.2
Wolk, S.3
Weissman, M.M.4
-
48
-
-
70349110046
-
Depression, cortisol reactivity, and obesity in childhood and adolescence
-
Dockray S., Susman E.J., Dorn L.D. Depression, cortisol reactivity, and obesity in childhood and adolescence. J. Adolesc. Health 2009, 45:344-350.
-
(2009)
J. Adolesc. Health
, vol.45
, pp. 344-350
-
-
Dockray, S.1
Susman, E.J.2
Dorn, L.D.3
-
49
-
-
79955956506
-
The fat mass and obesity gene is linked to reduced verbal fluency in overweight and obese elderly men
-
Benedict C., Jacobsson J.A., Rönnemaa E., Sallman Almen M., Brooks S., Schultes B., Fredriksson R., Lannfelt L., Kilander L., Schiöth H.B. The fat mass and obesity gene is linked to reduced verbal fluency in overweight and obese elderly men. Neurobiol. Aging 2011, 32:1159.e1-1159.e5.
-
(2011)
Neurobiol. Aging
, vol.32
, pp. 1159.e1-1159.e5
-
-
Benedict, C.1
Jacobsson, J.A.2
Rönnemaa, E.3
Sallman Almen, M.4
Brooks, S.5
Schultes, B.6
Fredriksson, R.7
Lannfelt, L.8
Kilander, L.9
Schiöth, H.B.10
-
50
-
-
84875664101
-
Reduced memory in fat mass and obesity-associated allele carriers among older adults with cardiovascular disease
-
Alosco M.L., Benitez A., Gunstad J., Spitznagel M.B., McCaffery J.M., McGeary J.E., Poppas A., Paul R.H., Sweet L.H., Cohen R.A. Reduced memory in fat mass and obesity-associated allele carriers among older adults with cardiovascular disease. Psychogeriatrics 2013, 13:35-40.
-
(2013)
Psychogeriatrics
, vol.13
, pp. 35-40
-
-
Alosco, M.L.1
Benitez, A.2
Gunstad, J.3
Spitznagel, M.B.4
McCaffery, J.M.5
McGeary, J.E.6
Poppas, A.7
Paul, R.H.8
Sweet, L.H.9
Cohen, R.A.10
-
51
-
-
84873668493
-
Fat mass and obesity gene and cognitive decline: the atherosclerosis risk in communities study
-
Bressler J., Fornage M., Demerath E.W., Knopman D.S., Monda K.L., North K.E., Penman A., Mosley T.H., Boerwinkle E. Fat mass and obesity gene and cognitive decline: the atherosclerosis risk in communities study. Neurology 2013, 80:92-99.
-
(2013)
Neurology
, vol.80
, pp. 92-99
-
-
Bressler, J.1
Fornage, M.2
Demerath, E.W.3
Knopman, D.S.4
Monda, K.L.5
North, K.E.6
Penman, A.7
Mosley, T.H.8
Boerwinkle, E.9
-
52
-
-
77952340870
-
A commonly carried allele of the obesity-related FTO gene is associated with reduced brain volume in the healthy elderly
-
Ho A.J., Stein J.L., Hua X., Lee S., Hibar D.P., Leow A.D., Dinov I.D., Toga A.W., Saykin A.J., Shen L., Foroud T., Pankratz N., Huentelman M.J., Craig D.W., Gerber J.D., Allen A.N., Corneveaux J.J., Stephan D.A., Decarli C.S., Dechairo B.M., et al. A commonly carried allele of the obesity-related FTO gene is associated with reduced brain volume in the healthy elderly. Proc. Natl. Acad. Sci. U. S. A. 2010, 107(18):8404-8409.
-
(2010)
Proc. Natl. Acad. Sci. U. S. A.
, vol.107
, Issue.18
, pp. 8404-8409
-
-
Ho, A.J.1
Stein, J.L.2
Hua, X.3
Lee, S.4
Hibar, D.P.5
Leow, A.D.6
Dinov, I.D.7
Toga, A.W.8
Saykin, A.J.9
Shen, L.10
Foroud, T.11
Pankratz, N.12
Huentelman, M.J.13
Craig, D.W.14
Gerber, J.D.15
Allen, A.N.16
Corneveaux, J.J.17
Stephan, D.A.18
Decarli, C.S.19
Dechairo, B.M.20
more..
-
53
-
-
84887212356
-
Fatness-associated FTO gene variant increases mortality independent of fatness-in cohorts of Danish men
-
Zimmermann E., Kring S.I.I., Berentzen T.L., Holst C., Pers T.H., Hansen T., Pedersen O., Sorensen T.I.A., Jess T. Fatness-associated FTO gene variant increases mortality independent of fatness-in cohorts of Danish men. PLoS ONE 2009, 4:e4428.
-
(2009)
PLoS ONE
, vol.4
, pp. e4428
-
-
Zimmermann, E.1
Kring, S.I.I.2
Berentzen, T.L.3
Holst, C.4
Pers, T.H.5
Hansen, T.6
Pedersen, O.7
Sorensen, T.I.A.8
Jess, T.9
-
54
-
-
67649875640
-
Loss-of-function mutation in the dioxygenase-encoding FTO gene causes severe growth retardation and multiple malformations
-
Boissel S., Reish O., Proulx K., Kawagoe-Takaki H., Sedgwick B., Yeo G.S.H., Meyre D., Golzio C., Molinari F., Kadhom N., Etchevers H.C., Saudek V., Farooqi I.S., Froguel P., Lindahl T., O'Rahilly S., Munnich A., Colleaux L. Loss-of-function mutation in the dioxygenase-encoding FTO gene causes severe growth retardation and multiple malformations. Am. J. Hum. Genet. 2009, 85:106-111.
-
(2009)
Am. J. Hum. Genet.
, vol.85
, pp. 106-111
-
-
Boissel, S.1
Reish, O.2
Proulx, K.3
Kawagoe-Takaki, H.4
Sedgwick, B.5
Yeo, G.S.H.6
Meyre, D.7
Golzio, C.8
Molinari, F.9
Kadhom, N.10
Etchevers, H.C.11
Saudek, V.12
Farooqi, I.S.13
Froguel, P.14
Lindahl, T.15
O'Rahilly, S.16
Munnich, A.17
Colleaux, L.18
-
55
-
-
33748452843
-
Duplications of proximal 16q flanked by heterochromatin are not euchromatic variants and show no evidence of heterochromatic position effect
-
Barber J.C.K., Zhang S., Friend N., Collins A.L., Maloney V.K., Hastings R., Farren B., Barnicoat A., Polityko A.D., Rumyantseva N.V., Starke H., Ye S. Duplications of proximal 16q flanked by heterochromatin are not euchromatic variants and show no evidence of heterochromatic position effect. Cytogenet. Genome Res. 2006, 114:351-358.
-
(2006)
Cytogenet. Genome Res.
, vol.114
, pp. 351-358
-
-
Barber, J.C.K.1
Zhang, S.2
Friend, N.3
Collins, A.L.4
Maloney, V.K.5
Hastings, R.6
Farren, B.7
Barnicoat, A.8
Polityko, A.D.9
Rumyantseva, N.V.10
Starke, H.11
Ye, S.12
-
56
-
-
77649223723
-
Investigation of a patient with a partial trisomy 16q including the fat mass and obesity associated gene (FTO): fine mapping and FTO gene expression study
-
van den Berg L., de Waal H.D.-V., Han J.C., Ylstra B., Eijk P., Nesterova M., Heutink P., Stratakis C.A. Investigation of a patient with a partial trisomy 16q including the fat mass and obesity associated gene (FTO): fine mapping and FTO gene expression study. Am. J. Med. Genet. A 2010, 152A:630-637.
-
(2010)
Am. J. Med. Genet. A
, vol.152 A
, pp. 630-637
-
-
van den Berg, L.1
de Waal, H.D.-V.2
Han, J.C.3
Ylstra, B.4
Eijk, P.5
Nesterova, M.6
Heutink, P.7
Stratakis, C.A.8
-
57
-
-
77649303960
-
Hypothalamic-specific manipulation of Fto, the ortholog of the human obesity gene FTO, affects food intake in rats
-
Tung Y.-C.L., Ayuso E., Shan X., Bosch F., O'Rahilly S., Coll A.P., Yeo G.S.H. Hypothalamic-specific manipulation of Fto, the ortholog of the human obesity gene FTO, affects food intake in rats. PLoS ONE 2010, 5:e8771.
-
(2010)
PLoS ONE
, vol.5
, pp. e8771
-
-
Tung, Y.-C.L.1
Ayuso, E.2
Shan, X.3
Bosch, F.4
O'Rahilly, S.5
Coll, A.P.6
Yeo, G.S.H.7
-
58
-
-
82355194591
-
FTO is expressed in neurones throughout the brain and its expression is unaltered by fasting
-
McTaggart J.S., Lee S., Iberl M., Church C., Cox R.D., Ashcroft F.M. FTO is expressed in neurones throughout the brain and its expression is unaltered by fasting. PLoS ONE 2011, 6.
-
(2011)
PLoS ONE
, vol.6
-
-
McTaggart, J.S.1
Lee, S.2
Iberl, M.3
Church, C.4
Cox, R.D.5
Ashcroft, F.M.6
-
59
-
-
42249083837
-
The obesity gene FTO, is of ancient origin, up-regulated during food deprivation and expressed in neurons of feeding-related nuclei of the brain
-
Fredriksson R., Hägglund M., Olszewski P.K., Stephansson O., Jacobsson J.A., Olszewska A.M., Levine A.S., Lindblom J., Schiöth H.B. The obesity gene FTO, is of ancient origin, up-regulated during food deprivation and expressed in neurons of feeding-related nuclei of the brain. Endocrinology 2008, 149:2062-2071.
-
(2008)
Endocrinology
, vol.149
, pp. 2062-2071
-
-
Fredriksson, R.1
Hägglund, M.2
Olszewski, P.K.3
Stephansson, O.4
Jacobsson, J.A.5
Olszewska, A.M.6
Levine, A.S.7
Lindblom, J.8
Schiöth, H.B.9
-
60
-
-
81355146483
-
N6-methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO
-
Jia G., Fu Y., Zhao X., Dai Q., Zheng G., Yang Y., Yi C., Lindahl T., Pan T., Yang Y.-G., He C. N6-methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO. Nat. Chem. Biol. 2011, 7:885-887.
-
(2011)
Nat. Chem. Biol.
, vol.7
, pp. 885-887
-
-
Jia, G.1
Fu, Y.2
Zhao, X.3
Dai, Q.4
Zheng, G.5
Yang, Y.6
Yi, C.7
Lindahl, T.8
Pan, T.9
Yang, Y.-G.10
He, C.11
-
61
-
-
84874113202
-
FTO levels affect RNA modification and the transcriptome
-
Berulava T., Ziehe M., Klein-Hitpass L., Mladenov E., Thomale J., Rüther U., Horsthemke B. FTO levels affect RNA modification and the transcriptome. Eur. J. Hum. Genet. 2013, 21:317-323.
-
(2013)
Eur. J. Hum. Genet.
, vol.21
, pp. 317-323
-
-
Berulava, T.1
Ziehe, M.2
Klein-Hitpass, L.3
Mladenov, E.4
Thomale, J.5
Rüther, U.6
Horsthemke, B.7
-
62
-
-
79957945033
-
Involvement of leptin receptor long isoform (LepRb)-STAT3 signaling pathway in brain fat mass- and obesity-associated (FTO) downregulation during energy restriction
-
Wang P., Yang F.-J., Du H., Guan Y.-F., Xu T.-Y., Xu X.-W., Su D.-F., Miao C.-Y. Involvement of leptin receptor long isoform (LepRb)-STAT3 signaling pathway in brain fat mass- and obesity-associated (FTO) downregulation during energy restriction. Mol. Med. 2011, 17:523-532.
-
(2011)
Mol. Med.
, vol.17
, pp. 523-532
-
-
Wang, P.1
Yang, F.-J.2
Du, H.3
Guan, Y.-F.4
Xu, T.-Y.5
Xu, X.-W.6
Su, D.-F.7
Miao, C.-Y.8
-
63
-
-
78649459183
-
Overexpression of Fto leads to increased food intake and results in obesity
-
Church C., Moir L., McMurray F., Girard C., Banks G.T., Teboul L., Wells S., Brüning J.C., Nolan P.M., Ashcroft F.M., Cox R.D. Overexpression of Fto leads to increased food intake and results in obesity. Nat. Genet. 2010, 42:1086-1092.
-
(2010)
Nat. Genet.
, vol.42
, pp. 1086-1092
-
-
Church, C.1
Moir, L.2
McMurray, F.3
Girard, C.4
Banks, G.T.5
Teboul, L.6
Wells, S.7
Brüning, J.C.8
Nolan, P.M.9
Ashcroft, F.M.10
Cox, R.D.11
-
64
-
-
84877577199
-
FTO expression is regulated by availability of essential amino acids
-
Cheung M.K., Gulati P., O'Rahilly S., Yeo G.S.H. FTO expression is regulated by availability of essential amino acids. Int. J. Obes. (Lond.) 2013, 37:744-747.
-
(2013)
Int. J. Obes. (Lond.)
, vol.37
, pp. 744-747
-
-
Cheung, M.K.1
Gulati, P.2
O'Rahilly, S.3
Yeo, G.S.H.4
-
65
-
-
67349211789
-
Inactivation of the Fto gene protects from obesity
-
Fischer J., Koch L., Emmerling C., Vierkotten J., Peters T., Brüning J.C., Rüther U. Inactivation of the Fto gene protects from obesity. Nature 2009, 458:894-898.
-
(2009)
Nature
, vol.458
, pp. 894-898
-
-
Fischer, J.1
Koch, L.2
Emmerling, C.3
Vierkotten, J.4
Peters, T.5
Brüning, J.C.6
Rüther, U.7
-
66
-
-
84873735640
-
Role for the obesity-related FTO gene in the cellular sensing of amino acids
-
Gulati P., Cheung M.K., Antrobus R., Church C.D., Harding H.P., Tung Y.-C.L., Rimmington D., Ma M., Ron D., Lehner P.J., Ashcroft F.M., Cox R.D., Coll A.P., O'Rahilly S., Yeo G.S.H. Role for the obesity-related FTO gene in the cellular sensing of amino acids. Proc. Natl. Acad. Sci. 2013, 110(7):2557-2562.
-
(2013)
Proc. Natl. Acad. Sci.
, vol.110
, Issue.7
, pp. 2557-2562
-
-
Gulati, P.1
Cheung, M.K.2
Antrobus, R.3
Church, C.D.4
Harding, H.P.5
Tung, Y.-C.L.6
Rimmington, D.7
Ma, M.8
Ron, D.9
Lehner, P.J.10
Ashcroft, F.M.11
Cox, R.D.12
Coll, A.P.13
O'Rahilly, S.14
Yeo, G.S.H.15
-
67
-
-
39049154918
-
The FTO (fat mass and obesity associated) gene codes for a novel member of the non-heme dioxygenase superfamily
-
Sanchez-Pulido L., Andrade-Navarro M.A. The FTO (fat mass and obesity associated) gene codes for a novel member of the non-heme dioxygenase superfamily. BMC Biochem. 2007, 8:23.
-
(2007)
BMC Biochem.
, vol.8
, pp. 23
-
-
Sanchez-Pulido, L.1
Andrade-Navarro, M.A.2
-
68
-
-
77951623073
-
Crystal structure of the FTO protein reveals basis for its substrate specificity
-
Han Z., Niu T., Chang J., Lei X., Zhao M., Wang Q., Cheng W., Wang J., Feng Y., Chai J. Crystal structure of the FTO protein reveals basis for its substrate specificity. Nature 2010, 464:1205-1209.
-
(2010)
Nature
, vol.464
, pp. 1205-1209
-
-
Han, Z.1
Niu, T.2
Chang, J.3
Lei, X.4
Zhao, M.5
Wang, Q.6
Cheng, W.7
Wang, J.8
Feng, Y.9
Chai, J.10
-
69
-
-
84860871770
-
Kinetic analysis of FTO (fat mass and obesity-associated) reveals that it is unlikely to function as a sensor for 2-oxoglutarate
-
Ma M., Harding H.P., O'Rahilly S., Ron D., Yeo G.S.H. Kinetic analysis of FTO (fat mass and obesity-associated) reveals that it is unlikely to function as a sensor for 2-oxoglutarate. Biochem. J. 2012, 444:183-187.
-
(2012)
Biochem. J.
, vol.444
, pp. 183-187
-
-
Ma, M.1
Harding, H.P.2
O'Rahilly, S.3
Ron, D.4
Yeo, G.S.H.5
-
70
-
-
54849381000
-
Oxidative demethylation of 3-methylthymine and 3-methyluracil in single-stranded DNA and RNA by mouse and human FTO
-
Jia G., Yang C.-G., Yang S., Jian X., Yi C., Zhou Z., He C. Oxidative demethylation of 3-methylthymine and 3-methyluracil in single-stranded DNA and RNA by mouse and human FTO. FEBS Lett. 2008, 582:3313-3319.
-
(2008)
FEBS Lett.
, vol.582
, pp. 3313-3319
-
-
Jia, G.1
Yang, C.-G.2
Yang, S.3
Jian, X.4
Yi, C.5
Zhou, Z.6
He, C.7
-
71
-
-
84862649489
-
Comprehensive analysis of mRNA methylation reveals enrichment in 3' UTRs and near stop codons
-
Meyer K.D., Saletore Y., Zumbo P., Elemento O., Mason C.E., Jaffrey S.R. Comprehensive analysis of mRNA methylation reveals enrichment in 3' UTRs and near stop codons. Cell 2012, 149:1635-1646.
-
(2012)
Cell
, vol.149
, pp. 1635-1646
-
-
Meyer, K.D.1
Saletore, Y.2
Zumbo, P.3
Elemento, O.4
Mason, C.E.5
Jaffrey, S.R.6
-
72
-
-
0016285746
-
Identification of methylated nucleosides in messenger RNA from Novikoff hepatoma cells
-
Desrosiers R., Friderici K., Rottman F. Identification of methylated nucleosides in messenger RNA from Novikoff hepatoma cells. Proc. Natl. Acad. Sci. U. S. A. 1974, 71:3971-3975.
-
(1974)
Proc. Natl. Acad. Sci. U. S. A.
, vol.71
, pp. 3971-3975
-
-
Desrosiers, R.1
Friderici, K.2
Rottman, F.3
-
73
-
-
84872847340
-
Reversible RNA adenosine methylation in biological regulation
-
Jia G., Fu Y., He C. Reversible RNA adenosine methylation in biological regulation. Trends Genet. 2012, 29:108-115.
-
(2012)
Trends Genet.
, vol.29
, pp. 108-115
-
-
Jia, G.1
Fu, Y.2
He, C.3
-
74
-
-
23844464444
-
Suppression of RNA recognition by Toll-like receptors: the impact of nucleoside modification and the evolutionary origin of RNA
-
Karikó K., Buckstein M., Ni H., Weissman D. Suppression of RNA recognition by Toll-like receptors: the impact of nucleoside modification and the evolutionary origin of RNA. Immunity 2005, 23:165-175.
-
(2005)
Immunity
, vol.23
, pp. 165-175
-
-
Karikó, K.1
Buckstein, M.2
Ni, H.3
Weissman, D.4
-
75
-
-
84860779086
-
6A-seq
-
6A-seq. Nature 2012, 485:201-206.
-
(2012)
Nature
, vol.485
, pp. 201-206
-
-
Dominissini, D.1
Moshitch-Moshkovitz, S.2
Schwartz, S.3
Salmon-Divon, M.4
Ungar, L.5
Osenberg, S.6
Cesarkas, K.7
Jacob-Hirsch, J.8
Amariglio, N.9
Kupiec, M.10
Sorek, R.11
Rechavi, G.12
-
76
-
-
84880916638
-
The fat mass and obesity associated gene (Fto) regulates activity of the dopaminergic midbrain circuitry
-
Hess M.E., Hess S., Meyer K.D., Verhagen L.A.W., Koch L., Brönneke H.S., Dietrich M.O., Jordan S.D., Saletore Y., Elemento O., Belgardt B.F., Franz T., Horvath T.L., Rüther U., Jaffrey S.R., Kloppenburg P., Brüning J.C. The fat mass and obesity associated gene (Fto) regulates activity of the dopaminergic midbrain circuitry. Nat. Neurosci. 2013, 16:1042-1048.
-
(2013)
Nat. Neurosci.
, vol.16
, pp. 1042-1048
-
-
Hess, M.E.1
Hess, S.2
Meyer, K.D.3
Verhagen, L.A.W.4
Koch, L.5
Brönneke, H.S.6
Dietrich, M.O.7
Jordan, S.D.8
Saletore, Y.9
Elemento, O.10
Belgardt, B.F.11
Franz, T.12
Horvath, T.L.13
Rüther, U.14
Jaffrey, S.R.15
Kloppenburg, P.16
Brüning, J.C.17
-
77
-
-
84872274463
-
ALKBH5 is a mammalian RNA demethylase that impacts RNA metabolism and mouse fertility
-
Zheng G., Dahl J.A., Niu Y., Fedorcsak P., Huang C.-M., Li C.J., Vågbø C.B., Shi Y., Wang W.-L., Song S.-H., Lu Z., Bosmans R.P.G., Dai Q., Hao Y.-J., Yang X., Zhao W.-M., Tong W.-M., Wang X.-J., Bogdan F., Furu K., et al. ALKBH5 is a mammalian RNA demethylase that impacts RNA metabolism and mouse fertility. Mol. Cell 2013, 49(1):18-29.
-
(2013)
Mol. Cell
, vol.49
, Issue.1
, pp. 18-29
-
-
Zheng, G.1
Dahl, J.A.2
Niu, Y.3
Fedorcsak, P.4
Huang, C.-M.5
Li, C.J.6
Vågbø, C.B.7
Shi, Y.8
Wang, W.-L.9
Song, S.-H.10
Lu, Z.11
Bosmans, R.P.G.12
Dai, Q.13
Hao, Y.-J.14
Yang, X.15
Zhao, W.-M.16
Tong, W.-M.17
Wang, X.-J.18
Bogdan, F.19
Furu, K.20
more..
-
78
-
-
84873520661
-
Adult onset global loss of the fto gene alters body composition and metabolism in the mouse
-
McMurray F., Church C.D., Larder R., Nicholson G., Wells S., Teboul L., Tung Y.C.L., Rimmington D., Bosch F., Jimenez V., Yeo G.S.H., O'Rahilly S., Ashcroft F.M., Coll A.P., Cox R.D. Adult onset global loss of the fto gene alters body composition and metabolism in the mouse. PLoS Genet. 2013, 9:e1003166.
-
(2013)
PLoS Genet.
, vol.9
, pp. e1003166
-
-
McMurray, F.1
Church, C.D.2
Larder, R.3
Nicholson, G.4
Wells, S.5
Teboul, L.6
Tung, Y.C.L.7
Rimmington, D.8
Bosch, F.9
Jimenez, V.10
Yeo, G.S.H.11
O'Rahilly, S.12
Ashcroft, F.M.13
Coll, A.P.14
Cox, R.D.15
-
79
-
-
77955981202
-
The obesity-associated SNPs in intron 1 of the FTO gene affect primary transcript levels
-
Berulava T., Horsthemke B. The obesity-associated SNPs in intron 1 of the FTO gene affect primary transcript levels. Eur. J. Hum. Genet. 2010, 18:1054-1056.
-
(2010)
Eur. J. Hum. Genet.
, vol.18
, pp. 1054-1056
-
-
Berulava, T.1
Horsthemke, B.2
-
80
-
-
41149087641
-
Inverse relationship between obesity and FTO gene expression in visceral adipose tissue in humans
-
Kloeting N., Schleinitz D., Ruschke K., Berndt J., Fasshauer M., Toenjes A., Schoen M.R., Kovacs P., Stumvoll M., Blueher M. Inverse relationship between obesity and FTO gene expression in visceral adipose tissue in humans. Diabetologia 2008, 51:641-647.
-
(2008)
Diabetologia
, vol.51
, pp. 641-647
-
-
Kloeting, N.1
Schleinitz, D.2
Ruschke, K.3
Berndt, J.4
Fasshauer, M.5
Toenjes, A.6
Schoen, M.R.7
Kovacs, P.8
Stumvoll, M.9
Blueher, M.10
-
81
-
-
78650959240
-
Regulation of FTO and FTM expression during human preadipocyte differentiation
-
Tews D., Fischer-Posovszky P., Wabitsch M. Regulation of FTO and FTM expression during human preadipocyte differentiation. Horm. Metab. Res. 2011, 43:17-21.
-
(2011)
Horm. Metab. Res.
, vol.43
, pp. 17-21
-
-
Tews, D.1
Fischer-Posovszky, P.2
Wabitsch, M.3
-
82
-
-
42949102733
-
The common rs9939609 gene variant of the fat mass- and obesity-associated gene FTO is related to fat cell lipolysis
-
Wåhlén K., Sjölin E., Hoffstedt J. The common rs9939609 gene variant of the fat mass- and obesity-associated gene FTO is related to fat cell lipolysis. J. Lipid Res. 2008, 49:607-611.
-
(2008)
J. Lipid Res.
, vol.49
, pp. 607-611
-
-
Wåhlén, K.1
Sjölin, E.2
Hoffstedt, J.3
-
83
-
-
84883169345
-
FTO deficiency induces UCP-1 expression and mitochondrial uncoupling in adipocytes
-
Tews D., Fischer-Posovszky P., Fromme T. FTO deficiency induces UCP-1 expression and mitochondrial uncoupling in adipocytes. Endocrinology 2013, 154(9):3141-3151.
-
(2013)
Endocrinology
, vol.154
, Issue.9
, pp. 3141-3151
-
-
Tews, D.1
Fischer-Posovszky, P.2
Fromme, T.3
-
85
-
-
78649512744
-
The fat mass and obesity associated gene FTO functions in the brain to regulate postnatal growth in mice
-
Gao X., Shin Y., Li M., Wang F., Tong Q., Zhang P. The fat mass and obesity associated gene FTO functions in the brain to regulate postnatal growth in mice. PLoS ONE 2010, 5(11):e14005.
-
(2010)
PLoS ONE
, vol.5
, Issue.11
, pp. e14005
-
-
Gao, X.1
Shin, Y.2
Li, M.3
Wang, F.4
Tong, Q.5
Zhang, P.6
-
86
-
-
77955405459
-
Nestin-Cre mice are affected by hypopituitarism, which is not due to significant activity of the transgene in the pituitary gland
-
Galichet C., Lovell-Badge R., Rizzoti K. Nestin-Cre mice are affected by hypopituitarism, which is not due to significant activity of the transgene in the pituitary gland. PLoS ONE 2010, 5:e11443.
-
(2010)
PLoS ONE
, vol.5
, pp. e11443
-
-
Galichet, C.1
Lovell-Badge, R.2
Rizzoti, K.3
-
87
-
-
79960836822
-
Cocaine supersensitivity and enhanced motivation for reward in mice lacking dopamine D2 autoreceptors
-
Bello E.P., Mateo Y., Gelman D.M., Noaín D., Shin J.H., Low M.J., Alvarez V.A., Lovinger D.M., Rubinstein M. Cocaine supersensitivity and enhanced motivation for reward in mice lacking dopamine D2 autoreceptors. Nat. Neurosci. 2011, 14:1033-1038.
-
(2011)
Nat. Neurosci.
, vol.14
, pp. 1033-1038
-
-
Bello, E.P.1
Mateo, Y.2
Gelman, D.M.3
Noaín, D.4
Shin, J.H.5
Low, M.J.6
Alvarez, V.A.7
Lovinger, D.M.8
Rubinstein, M.9
-
88
-
-
84871241900
-
Obesity and addiction: neurobiological overlaps
-
Volkow N.D., Wang G.J., Tomasi D., Baler R.D. Obesity and addiction: neurobiological overlaps. Obes. Rev. 2013, 14:2-18.
-
(2013)
Obes. Rev.
, vol.14
, pp. 2-18
-
-
Volkow, N.D.1
Wang, G.J.2
Tomasi, D.3
Baler, R.D.4
-
89
-
-
79952032110
-
The physiology, signaling, and pharmacology of dopamine receptors
-
Beaulieu J.-M., Gainetdinov R.R. The physiology, signaling, and pharmacology of dopamine receptors. Pharmacol. Rev. 2011, 63:182-217.
-
(2011)
Pharmacol. Rev.
, vol.63
, pp. 182-217
-
-
Beaulieu, J.-M.1
Gainetdinov, R.R.2
-
90
-
-
84898423633
-
Ghrelin and eating behavior: evidence and insights from genetically-modified mouse models
-
Uchida A., Zigman J.M., Perelló M. Ghrelin and eating behavior: evidence and insights from genetically-modified mouse models. Front. Neurosci. 2013, 7:121.
-
(2013)
Front. Neurosci.
, vol.7
, pp. 121
-
-
Uchida, A.1
Zigman, J.M.2
Perelló, M.3
-
91
-
-
84863449483
-
Obesity and ADHD: clinical and neurobiological implications
-
Cortese S., Vincenzi B. Obesity and ADHD: clinical and neurobiological implications. Curr. Top. Behav. Neurosci. 2012, 9:199-218.
-
(2012)
Curr. Top. Behav. Neurosci.
, vol.9
, pp. 199-218
-
-
Cortese, S.1
Vincenzi, B.2
-
92
-
-
77649217019
-
Overweight, obesity, and depression: a systematic review and meta-analysis of longitudinal studies
-
Luppino F.S., de Wit L.M., Bouvy P.F., Stijnen T., Cuijpers P., Penninx B.W.J.H., Zitman F.G. Overweight, obesity, and depression: a systematic review and meta-analysis of longitudinal studies. Arch. Gen. Psychiatry 2010, 67:220-229.
-
(2010)
Arch. Gen. Psychiatry
, vol.67
, pp. 220-229
-
-
Luppino, F.S.1
de Wit, L.M.2
Bouvy, P.F.3
Stijnen, T.4
Cuijpers, P.5
Penninx, B.W.J.H.6
Zitman, F.G.7
-
93
-
-
68649118810
-
'Liking' and 'wanting' food rewards: brain substrates and roles in eating disorders
-
Berridge K.C. 'Liking' and 'wanting' food rewards: brain substrates and roles in eating disorders. Physiol. Behav. 2009, 97:537-550.
-
(2009)
Physiol. Behav.
, vol.97
, pp. 537-550
-
-
Berridge, K.C.1
-
94
-
-
77649200393
-
Development of hypothalamic neural networks controlling appetite
-
Bouret S.G. Development of hypothalamic neural networks controlling appetite. Forum Nutr. 2010, 63:84-93.
-
(2010)
Forum Nutr.
, vol.63
, pp. 84-93
-
-
Bouret, S.G.1
|