-
1
-
-
51849146897
-
Global burden of obesity in 2005 and projections to 2030
-
Kelly T, Yang W, Chen C-S, Reynolds K, He J, (2008) Global burden of obesity in 2005 and projections to 2030. International journal of obesity (2005) 32: 1431-1437.
-
(2008)
International Journal of Obesity in 2005
, vol.32
, pp. 1431-1437
-
-
Kelly, T.1
Yang, W.2
Chen, C.-S.3
Reynolds, K.4
He, J.5
-
2
-
-
34248594090
-
A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity
-
Frayling TM, Timpson NJ, Weedon MN, Zeggini E, Freathy RM, et al. (2007) A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. Science 316: 889-894.
-
(2007)
Science
, vol.316
, pp. 889-894
-
-
Frayling, T.M.1
Timpson, N.J.2
Weedon, M.N.3
Zeggini, E.4
Freathy, R.M.5
-
3
-
-
34249777814
-
Variation in FTO contributes to childhood obesity and severe adult obesity
-
Dina C, Meyre D, Gallina S, Durand E, Körner A, et al. (2007) Variation in FTO contributes to childhood obesity and severe adult obesity. Nat Genet 39: 724-726.
-
(2007)
Nat Genet
, vol.39
, pp. 724-726
-
-
Dina, C.1
Meyre, D.2
Gallina, S.3
Durand, E.4
Körner, A.5
-
4
-
-
34547625955
-
Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits
-
Scuteri A, Sanna S, Chen WM, Uda M, Albai G, et al. (2007) Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits. PLoS Genet 3: e115.
-
(2007)
PLoS Genet
, vol.3
-
-
Scuteri, A.1
Sanna, S.2
Chen, W.M.3
Uda, M.4
Albai, G.5
-
5
-
-
57749121512
-
An obesity-associated FTO gene variant and increased energy intake in children
-
Cecil JE, Tavendale R, Watt P, Hetherington MM, Palmer CN, (2008) An obesity-associated FTO gene variant and increased energy intake in children. N Engl J Med 359: 2558-2566.
-
(2008)
N Engl J Med
, vol.359
, pp. 2558-2566
-
-
Cecil, J.E.1
Tavendale, R.2
Watt, P.3
Hetherington, M.M.4
Palmer, C.N.5
-
6
-
-
48749132799
-
Polymorphisms of the FTO gene are associated with variation in energy intake, but not energy expenditure
-
(Silver Spring)
-
Speakman JR, Rance KA, Johnstone AM, (2008) Polymorphisms of the FTO gene are associated with variation in energy intake, but not energy expenditure. Obesity (Silver Spring) 16: 1961-1965.
-
(2008)
Obesity
, vol.16
, pp. 1961-1965
-
-
Speakman, J.R.1
Rance, K.A.2
Johnstone, A.M.3
-
8
-
-
53849088890
-
The fat mass- and obesity-associated locus and dietary intake in children
-
Timpson NJ, Emmett PM, Frayling TM, Rogers I, Hattersley AT, et al. (2008) The fat mass- and obesity-associated locus and dietary intake in children. Am J Clin Nutr 88: 971-978.
-
(2008)
Am J Clin Nutr
, vol.88
, pp. 971-978
-
-
Timpson, N.J.1
Emmett, P.M.2
Frayling, T.M.3
Rogers, I.4
Hattersley, A.T.5
-
9
-
-
72749115949
-
The FTO gene rs9939609 obesity-risk allele and loss of control over eating
-
Tanofsky-Kraff M, Han JC, Anandalingam K, Shomaker LB, Columbo KM, et al. (2009) The FTO gene rs9939609 obesity-risk allele and loss of control over eating. Am J Clin Nutr 90: 1483-1488.
-
(2009)
Am J Clin Nutr
, vol.90
, pp. 1483-1488
-
-
Tanofsky-Kraff, M.1
Han, J.C.2
Anandalingam, K.3
Shomaker, L.B.4
Columbo, K.M.5
-
10
-
-
78649459183
-
Overexpression of Fto leads to increased food intake and results in obesity
-
Church C, Moir L, Mcmurray F, Girard C, Banks GT, et al. (2010) Overexpression of Fto leads to increased food intake and results in obesity. Nat Genet 42: 1086-1092.
-
(2010)
Nat Genet
, vol.42
, pp. 1086-1092
-
-
Church, C.1
Moir, L.2
McMurray, F.3
Girard, C.4
Banks, G.T.5
-
11
-
-
67349211789
-
Inactivation of the Fto gene protects from obesity
-
Fischer J, Koch L, Emmerling C, Vierkotten J, Peters T, et al. (2009) Inactivation of the Fto gene protects from obesity. Nature pp. 1-6.
-
(2009)
Nature
, pp. 1-6
-
-
Fischer, J.1
Koch, L.2
Emmerling, C.3
Vierkotten, J.4
Peters, T.5
-
12
-
-
70149100469
-
A mouse model for the metabolic effects of the human fat mass and obesity associated FTO gene
-
Church C, Lee S, Bagg EA, McTaggart JS, Deacon R, et al. (2009) A mouse model for the metabolic effects of the human fat mass and obesity associated FTO gene. PLoS Genet 5: e1000599.
-
(2009)
PLoS Genet
, vol.5
-
-
Church, C.1
Lee, S.2
Bagg, E.A.3
McTaggart, J.S.4
Deacon, R.5
-
13
-
-
77649303960
-
Hypothalamic-specific manipulation of Fto, the ortholog of the human obesity gene FTO, affects food intake in rats
-
Tung YC, Ayuso E, Shan X, Bosch F, O'Rahilly S, et al. (2010) Hypothalamic-specific manipulation of Fto, the ortholog of the human obesity gene FTO, affects food intake in rats. PLoS ONE 5: e8771.
-
(2010)
PLoS ONE
, vol.5
-
-
Tung, Y.C.1
Ayuso, E.2
Shan, X.3
Bosch, F.4
O'Rahilly, S.5
-
14
-
-
33748931457
-
Central nervous system control of food intake and body weight
-
Morton GJ, Cummings DE, Baskin DG, Barsh GS, Schwartz MW, (2006) Central nervous system control of food intake and body weight. Nature 443: 289-295.
-
(2006)
Nature
, vol.443
, pp. 289-295
-
-
Morton, G.J.1
Cummings, D.E.2
Baskin, D.G.3
Barsh, G.S.4
Schwartz, M.W.5
-
15
-
-
42249083837
-
The obesity gene, FTO, is of ancient origin, up-regulated during food deprivation and expressed in neurons of feeding-related nuclei of the brain
-
Fredriksson R, Hägglund M, Olszewski PK, Stephansson O, Jacobsson JA, et al. (2008) The obesity gene, FTO, is of ancient origin, up-regulated during food deprivation and expressed in neurons of feeding-related nuclei of the brain. Endocrinology 149: 2062-2071.
-
(2008)
Endocrinology
, vol.149
, pp. 2062-2071
-
-
Fredriksson, R.1
Hägglund, M.2
Olszewski, P.K.3
Stephansson, O.4
Jacobsson, J.A.5
-
16
-
-
36749041363
-
The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase
-
Gerken T, Girard CA, Tung YC, Webby CJ, Saudek V, et al. (2007) The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase. Science 318: 1469-1472.
-
(2007)
Science
, vol.318
, pp. 1469-1472
-
-
Gerken, T.1
Girard, C.A.2
Tung, Y.C.3
Webby, C.J.4
Saudek, V.5
-
17
-
-
41749092048
-
Regulation of Fto/Ftm gene expression in mice and humans
-
Stratigopoulos G, Padilla SL, LeDuc CA, Watson E, Hattersley AT, et al. (2008) Regulation of Fto/Ftm gene expression in mice and humans. Am J Physiol Regul Integr Comp Physiol 294: R1185-1196.
-
(2008)
Am J Physiol Regul Integr Comp Physiol
, vol.294
-
-
Stratigopoulos, G.1
Padilla, S.L.2
LeDuc, C.A.3
Watson, E.4
Hattersley, A.T.5
-
18
-
-
77957657096
-
In vivo differential effects of fasting, re-feeding, insulin and insulin stimulation time course on insulin signaling pathway components in peripheral tissues
-
Agouni A, Owen C, Czopek A, Mody N, Delibegovic M, (2010) In vivo differential effects of fasting, re-feeding, insulin and insulin stimulation time course on insulin signaling pathway components in peripheral tissues. Biochem Biophys Res Commun 401: 104-111.
-
(2010)
Biochem Biophys Res Commun
, vol.401
, pp. 104-111
-
-
Agouni, A.1
Owen, C.2
Czopek, A.3
Mody, N.4
Delibegovic, M.5
-
19
-
-
77951212602
-
Impaired glucose tolerance and predisposition to the fasted state in liver glycogen synthase knock-out mice
-
Irimia JM, Meyer CM, Peper CL, Zhai L, Bock CB, et al. (2010) Impaired glucose tolerance and predisposition to the fasted state in liver glycogen synthase knock-out mice. J Biol Chem 285: 12851-12861.
-
(2010)
J Biol Chem
, vol.285
, pp. 12851-12861
-
-
Irimia, J.M.1
Meyer, C.M.2
Peper, C.L.3
Zhai, L.4
Bock, C.B.5
-
20
-
-
0020623557
-
Comparison of carbohydrate and lipid metabolism in mice and rats during fasting
-
Menahan LA, Sobocinski KA, (1983) Comparison of carbohydrate and lipid metabolism in mice and rats during fasting. Comp Biochem Physiol, B 74: 859-864.
-
(1983)
Comp Biochem Physiol, B
, vol.74
, pp. 859-864
-
-
Menahan, L.A.1
Sobocinski, K.A.2
-
21
-
-
69949189508
-
Accelerated fatty acid oxidation in muscle averts fasting-induced hepatic steatosis in SJL/J mice
-
Guan HP, Goldstein JL, Brown MS, Liang G, (2009) Accelerated fatty acid oxidation in muscle averts fasting-induced hepatic steatosis in SJL/J mice. J Biol Chem 284: 24644-24652.
-
(2009)
J Biol Chem
, vol.284
, pp. 24644-24652
-
-
Guan, H.P.1
Goldstein, J.L.2
Brown, M.S.3
Liang, G.4
-
22
-
-
34948883169
-
Lipids of the Fasting Mouse
-
Hodge H, MacLachlan P, Bloor W, Stoneburg C, Oleson M, et al. (1941) Lipids of the Fasting Mouse. Journal of Biological Chemistry 139: 897.
-
(1941)
Journal of Biological Chemistry
, vol.139
, pp. 897
-
-
Hodge, H.1
MacLachlan, P.2
Bloor, W.3
Stoneburg, C.4
Oleson, M.5
-
23
-
-
60849128805
-
Effect of starvation on the survival of male and female mice
-
Jikumaru M, Hiramoto K, Honma T, Sato EF, Sekiyama A, et al. (2007) Effect of starvation on the survival of male and female mice. Physiol Chem Phys Med NMR 39: 247-257.
-
(2007)
Physiol Chem Phys Med NMR
, vol.39
, pp. 247-257
-
-
Jikumaru, M.1
Hiramoto, K.2
Honma, T.3
Sato, E.F.4
Sekiyama, A.5
-
24
-
-
70549105941
-
Hypothalamic FTO is associated with the regulation of energy intake not feeding reward
-
Olszewski PK, Fredriksson R, Olszewska AM, Stephansson O, Alsiö J, et al. (2009) Hypothalamic FTO is associated with the regulation of energy intake not feeding reward. BMC neuroscience 10: 129.
-
(2009)
BMC Neuroscience
, vol.10
, pp. 129
-
-
Olszewski, P.K.1
Fredriksson, R.2
Olszewska, A.M.3
Stephansson, O.4
Alsiö, J.5
-
25
-
-
84873091557
-
-
Molecular medicine (Cambridge, Mass)
-
Wang P, Yang F, Du H, Guan Y, Xu T, et al. (2011) Involvement of Leptin Receptor (LepRb)-STAT3 Signaling Pathway in Brain FTO Downregulation during Energy Restriction Molecular medicine (Cambridge, Mass).
-
(2011)
Involvement of Leptin Receptor (LepRb)-STAT3 Signaling Pathway in Brain FTO Downregulation during Energy Restriction
-
-
Wang, P.1
Yang, F.2
Du, H.3
Guan, Y.4
Xu, T.5
-
26
-
-
0020392253
-
Correlation of parvalbumin concentration with relaxation speed in mammalian muscles
-
Heizmann CW, Berchtold MW, Rowlerson AM, (1982) Correlation of parvalbumin concentration with relaxation speed in mammalian muscles. Proc Natl Acad Sci USA 79: 7243-7247.
-
(1982)
Proc Natl Acad Sci USA
, vol.79
, pp. 7243-7247
-
-
Heizmann, C.W.1
Berchtold, M.W.2
Rowlerson, A.M.3
-
27
-
-
8844276054
-
Regulation of muscle fiber type and running endurance by PPARdelta
-
Wang YX, Zhang CL, Yu RT, Cho HK, Nelson MC, et al. (2004) Regulation of muscle fiber type and running endurance by PPARdelta. PLoS Biol 2: e294.
-
(2004)
PLoS Biol
, vol.2
-
-
Wang, Y.X.1
Zhang, C.L.2
Yu, R.T.3
Cho, H.K.4
Nelson, M.C.5
-
28
-
-
0026697724
-
NeuN, a neuronal specific nuclear protein in vertebrates
-
Mullen RJ, Buck CR, Smith AM, (1992) NeuN, a neuronal specific nuclear protein in vertebrates. Development 116: 201-211.
-
(1992)
Development
, vol.116
, pp. 201-211
-
-
Mullen, R.J.1
Buck, C.R.2
Smith, A.M.3
-
29
-
-
84873097401
-
N6-Methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO
-
Jia G, Fu Y, Zhao X, Dai Q, Zheng G, et al. N6-Methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO. Nat Chem Biol.
-
Nat Chem Biol
-
-
Jia, G.1
Fu, Y.2
Zhao, X.3
Dai, Q.4
Zheng, G.5
-
30
-
-
79951992387
-
AGRP neurons are sufficient to orchestrate feeding behavior rapidly and without training
-
Aponte Y, Atasoy D, Sternson SM, (2011) AGRP neurons are sufficient to orchestrate feeding behavior rapidly and without training. Nat Neurosci 14: 351-355.
-
(2011)
Nat Neurosci
, vol.14
, pp. 351-355
-
-
Aponte, Y.1
Atasoy, D.2
Sternson, S.M.3
-
31
-
-
2942733252
-
Leptin receptor signaling in POMC neurons is required for normal body weight homeostasis
-
Balthasar N, Coppari R, McMinn J, Liu SM, Lee CE, et al. (2004) Leptin receptor signaling in POMC neurons is required for normal body weight homeostasis. Neuron 42: 983-991.
-
(2004)
Neuron
, vol.42
, pp. 983-991
-
-
Balthasar, N.1
Coppari, R.2
McMinn, J.3
Liu, S.M.4
Lee, C.E.5
-
32
-
-
33846252240
-
Genome-wide atlas of gene expression in the adult mouse brain
-
Lein ES, Hawrylycz MJ, Ao N, Ayres M, Bensinger A, et al. (2007) Genome-wide atlas of gene expression in the adult mouse brain. Nature 445: 168-176.
-
(2007)
Nature
, vol.445
, pp. 168-176
-
-
Lein, E.S.1
Hawrylycz, M.J.2
Ao, N.3
Ayres, M.4
Bensinger, A.5
-
33
-
-
0029794358
-
NeuN: a useful neuronal marker for diagnostic histopathology
-
Wolf HK, Buslei R, Schmidt-Kastner R, Schmidt-Kastner PK, Pietsch T, et al. (1996) NeuN: a useful neuronal marker for diagnostic histopathology. J Histochem Cytochem 44: 1167-1171.
-
(1996)
J Histochem Cytochem
, vol.44
, pp. 1167-1171
-
-
Wolf, H.K.1
Buslei, R.2
Schmidt-Kastner, R.3
Schmidt-Kastner, P.K.4
Pietsch, T.5
-
34
-
-
77958150921
-
The obesity-associated Fto gene is a transcriptional coactivator
-
Wu Q, Saunders RA, Szkudlarek-Mikho M, Serna Idl, Chin K, (2010) The obesity-associated Fto gene is a transcriptional coactivator. Biochem Biophys Res Commun 401: 390-395.
-
(2010)
Biochem Biophys Res Commun
, vol.401
, pp. 390-395
-
-
Wu, Q.1
Saunders, R.A.2
Szkudlarek-Mikho, M.3
Serna, I.4
Chin, K.5
-
36
-
-
17344392308
-
A new mathematical model for relative quantification in real-time RT-PCR
-
Pfaffl MW, (2001) A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res 29: e45.
-
(2001)
Nucleic Acids Res
, vol.29
-
-
Pfaffl, M.W.1
|