A truncating mutation of Alms1 reduces the number of hypothalamic neuronal cilia in obese mice

Developmental Neurobiology

Volumn 73, Issue 1, 2013, Pages 1-13

  Heydet, Déborah ^a   Chen, Lesley X ^b   Larter, Claire Z ^a   Inglis, Chrystal ^b   Silverman, Michael A ^b   Farrell, Geoffrey C ^a   Leroux, Michel R ^b  

^a CANBERRA HOSPITAL   (Australia)

^b SIMON FRASER UNIVERSITY   (Canada)

Author keywords

Alms1; Hypothalamus; Obesity; Primary cilium

Indexed keywords

ALSTROM SYNDROME PROTEIN; BIOLOGICAL MARKER; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BARDET BIEDL SYNDROME; CELL ORGANELLE; CONTROLLED STUDY; DISEASE MARKER; FEMALE; GENE EXPRESSION; GENE MUTATION; GENETIC ANALYSIS; HEARING DISORDER; HYPERPHAGIA; HYPOTHALAMIC NEURONAL CILIA; IN VIVO STUDY; MORBID OBESITY; MOUSE; NERVE CELL; NONHUMAN; OBESITY; PHENOTYPE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; SATIETY; SIGNAL TRANSDUCTION; TRUNCATING MUTATION; VISUAL IMPAIRMENT; WESTERN BLOTTING;

ADENYLATE CYCLASE; ADIPOSE TISSUE; ADP-RIBOSYLATION FACTORS; AGE FACTORS; ANIMALS; ANIMALS, NEWBORN; CELLS, CULTURED; CILIA; DIABETES MELLITUS, EXPERIMENTAL; DNA-BINDING PROTEINS; EMBRYO, MAMMALIAN; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HIPPOCAMPUS; HYPOTHALAMUS; MICE; MICE, INBRED NOD; MICROTUBULE-ASSOCIATED PROTEINS; MUTATION; NEURONS; RECEPTORS, SOMATOSTATIN; RNA, MESSENGER;

EID: 84870761696     PISSN: 19328451     EISSN: 10974695     Source Type: Journal    
DOI: 10.1002/dneu.22031     Document Type: Article

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