-
1
-
-
34248594090
-
A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity
-
DOI 10.1126/science.1141634
-
Frayling TM, Timpson NJ, Weedon MN, Zeggini E, Freathy RM, Lindgren CM, Perry JR, Elliott KS, Lango H, Rayner NW, Shields B, Harries LW, Barrett JC, Ellard S, Groves CJ, Knight B, Patch AM, Ness AR, Ebrahim S, Lawlor DA, Ring SM, Ben-Shlomo Y, Jarvelin MR, Sovio U, Bennett AJ, Melzer D, Ferrucci L, Loos RJ, Barroso I,Wareham NJ, Karpe F, Owen KR, Cardon LR,Walker M, Hitman GA, Palmer CN, Doney AS, Morris AD, Smith GD, Hattersley AT, McCarthy MI (2007) A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. Science 316, 889-894. (Pubitemid 46764279)
-
(2007)
Science
, vol.316
, Issue.5826
, pp. 889-894
-
-
Frayling, T.M.1
Timpson, N.J.2
Weedon, M.N.3
Zeggini, E.4
Freathy, R.M.5
Lindgren, C.M.6
Perry, J.R.B.7
Elliott, K.S.8
Lango, H.9
Rayner, N.W.10
Shields, B.11
Harries, L.W.12
Barrett, J.C.13
Ellard, S.14
Groves, C.J.15
Knight, B.16
Patch, A.-M.17
Ness, A.R.18
Ebrahim, S.19
Lawlor, D.A.20
Ring, S.M.21
Ben-Shlomo, Y.22
Jarvelin, M.-R.23
Sovio, U.24
Bennett, A.J.25
Melzer, D.26
Ferrucci, L.27
Loos, R.J.F.28
Barroso, I.29
Wareham, N.J.30
Karpe, F.31
Owen, K.R.32
Cardon, L.R.33
Walker, M.34
Hitman, G.A.35
Palmer, C.N.A.36
Doney, A.S.F.37
Morris, A.D.38
Smith, G.D.39
Hattersley, A.T.40
McCarthy, M.I.41
more..
-
2
-
-
34548032087
-
Genome-wide association studies provide new insights into type 2 diabetes aetiology
-
DOI 10.1038/nrg2178, PII NRG2178
-
Frayling TM (2007) Genome-wide association studies provide newinsights into type 2 diabetes aetiology. Nat Rev Genet 8, 657-662. (Pubitemid 47281993)
-
(2007)
Nature Reviews Genetics
, vol.8
, Issue.9
, pp. 657-662
-
-
Frayling, T.M.1
-
3
-
-
77951623073
-
Crystal structure of the FTO protein reveals basis for its substrate specificity
-
Han Z, Niu T, Chang J, Lei X, Zhao M, Wang Q, Cheng W, Wang J, Feng Y, Chai J (2010) Crystal structure of the FTO protein reveals basis for its substrate specificity. Nature 464, 1205-1209.
-
(2010)
Nature
, vol.464
, pp. 1205-1209
-
-
Han, Z.1
Niu, T.2
Chang, J.3
Lei, X.4
Zhao, M.5
Wang, Q.6
Cheng, W.7
Wang, J.8
Feng, Y.9
Chai, J.10
-
4
-
-
42249083837
-
The obesity gene, FTO, is of ancient origin, up-regulated during food deprivation and expressed in neurons of feeding-related nuclei of the brain
-
DOI 10.1210/en.2007-1457
-
Fredriksson R, Hagglund M, Olszewski PK, Stephansson O, Jacobsson JA, Olszewska AM, Levine AS, Lindblom J, Schioth HB (2008) The obesity gene, FTO, is of ancient origin, up-regulated during food deprivation and expressed in neurons of feeding-related nuclei of the brain. Endocrinology 149, 2062-2071. (Pubitemid 351574484)
-
(2008)
Endocrinology
, vol.149
, Issue.5
, pp. 2062-2071
-
-
Fredriksson, R.1
Hagglund, M.2
Olszewski, P.K.3
Stephansson, O.4
Jacobsson, J.A.5
Olszewska, A.M.6
Levine, A.S.7
Lindblom, J.8
Schioth, H.B.9
-
5
-
-
34249777814
-
Variation in FTO contributes to childhood obesity and severe adult obesity
-
DOI 10.1038/ng2048, PII NG2048
-
Dina C, Meyre D, Gallina S, Durand E, Korner A, Jacobson P, Carlsson LM, Kiess W, Vatin V, Lecoeur C, Delplanque J, Vaillant E, Pattou F, Ruiz J, Weill J, Levy-Marchal C, Horber F, Potoczna N, Hercberg S, Le Stunff C, Bougneres P, Kovacs P, Marre M, Balkau B, Cauchi S, Chevre JC, Froguel P (2007) Variation in FTO contributes to childhood obesity and severe adult obesity. Nat Genet 39, 724-726. (Pubitemid 46848595)
-
(2007)
Nature Genetics
, vol.39
, Issue.6
, pp. 724-726
-
-
Dina, C.1
Meyre, D.2
Gallina, S.3
Durand, E.4
Korner, A.5
Jacobson, P.6
Carlsson, L.M.S.7
Kiess, W.8
Vatin, V.9
Lecoeur, C.10
Delplanque, J.11
Vaillant, E.12
Pattou, F.13
Ruiz, J.14
Weill, J.15
Levy-Marchal, C.16
Horber, F.17
Potoczna, N.18
Hercberg, S.19
Le Stunff, C.20
Bougneres, P.21
Kovacs, P.22
Marre, M.23
Balkau, B.24
Cauchi, S.25
Chevre, J.-C.26
Froguel, P.27
more..
-
6
-
-
33747058235
-
The cerebrocortical response to hyperinsulinemia is reduced in overweight humans: A magnetoencephalographic study
-
DOI 10.1073/pnas.0604404103
-
Tschritter O, Preissl H, Hennige AM, Stumvoll M, Porubska K, Frost R, Marx H, Klosel B, LutzenbergerW, Birbaumer N, Haring HU, Fritsche A (2006) The cerebrocortical response to hyperinsulinemia is reduced in overweight humans: a magnetoencephalographic study. Proc Natl Acad Sci U S A 103, 12103-12108. (Pubitemid 44215818)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.32
, pp. 12103-12108
-
-
Tschritter, O.1
Preissl, H.2
Hennige, A.M.3
Stumvoll, M.4
Porubska, K.5
Frost, R.6
Marx, H.7
Klosel, B.8
Lutzenberger, W.9
Birbaumer, N.10
Haring, H.-U.11
Fritsche, A.12
-
7
-
-
77950358315
-
Leptin reduces pathology and improves memory in a transgenic mouse model of Alzheimer's disease
-
Greco SJ, Bryan KJ, Sarkar S, Zhu X, Smith MA, Ashford JW, Johnston JM, Tezapsidis N, Casadesus G (2010) Leptin reduces pathology and improves memory in a transgenic mouse model of Alzheimer's disease. J Alzheimers Dis 19,1155-1167.
-
(2010)
J Alzheimers Dis
, vol.19
, pp. 1155-1167
-
-
Greco, S.J.1
Bryan, K.J.2
Sarkar, S.3
Zhu, X.4
Smith, M.A.5
Ashford, J.W.6
Johnston, J.M.7
Tezapsidis, N.8
Casadesus, G.9
-
8
-
-
77649303960
-
Hypothalamic-specific manipulation of FTO, the ortholog of the human obesity gene FTO, affects food intake in rats
-
Tung YC, Ayuso E, Shan X, Bosch F, O'Rahilly S, Coll AP, Yeo GS (2010) Hypothalamic-Specific Manipulation of FTO, the Ortholog of the Human Obesity Gene FTO, Affects Food Intake in Rats. PLoS ONE 5, e8771.
-
(2010)
PLoS ONE
, vol.5
-
-
Tung, Y.C.1
Ayuso, E.2
Shan, X.3
Bosch, F.4
O'Rahilly, S.5
Coll, A.P.6
Yeo, G.S.7
-
9
-
-
42449153273
-
Genetic variants of FTO influence adiposity, insulin sensitivity, leptin levels, and resting metabolic rate in the quebec family study
-
Do R, Bailey SD, Desbiens K, Belisle A, Montpetit A, Bouchard C, Perusse L, Vohl MC, Engert JC (2008) Genetic variants of FTO influence adiposity, insulin sensitivity, leptin levels, and resting metabolic rate in the Quebec Family Study. Diabetes 57, 1147-1150.
-
(2008)
Diabetes
, vol.57
, pp. 1147-1150
-
-
Do, R.1
Bailey, S.D.2
Desbiens, K.3
Belisle, A.4
Montpetit, A.5
Bouchard, C.6
Perusse, L.7
Vohl, M.C.8
Engert, J.C.9
-
10
-
-
77949331704
-
The FTO gene is associated with an atherogenic lipid profile and myocardial infarction in patients with type 2 diabetes: A Genetics of Diabetes Audit and Research Study in Tayside Scotland (Go-DARTS) study
-
Doney AS, Dannfald J, Kimber CH, Donnelly LA, Pearson E, Morris AD, Palmer CN (2009) The FTO gene is associated with an atherogenic lipid profile and myocardial infarction in patients with type 2 diabetes: a Genetics of Diabetes Audit and Research Study in Tayside Scotland (Go-DARTS) study. Circ Cardiovasc Genet 2, 255-259.
-
(2009)
Circ Cardiovasc Genet
, vol.2
, pp. 255-259
-
-
Doney, A.S.1
Dannfald, J.2
Kimber, C.H.3
Donnelly, L.A.4
Pearson, E.5
Morris, A.D.6
Palmer, C.N.7
-
11
-
-
77952340870
-
A commonly carried allele of the obesity-related FTO gene is associated with reduced brain volume in the healthy elderly
-
Ho AJ, Stein JL, Hua X, Lee S, Hibar DP, Leow AD, Dinov ID, Toga AW, Saykin AJ, Shen L, Foroud T, Pankratz N, Huentelman MJ, Craig DW, Gerber JD, Allen AN, Corneveaux JJ, Stephan DA, Decarli CS, Dechairo BM, Potkin SG, Jack CR, Jr., Weiner MW, Raji CA, Lopez OL, Becker JT, Carmichael OT, Thompson PM (2010) A commonly carried allele of the obesity-related FTO gene is associated with reduced brain volume in the healthy elderly. Proc Natl Acad Sci U S A 107, 8404-8409.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 8404-8409
-
-
Ho, A.J.1
Stein, J.L.2
Hua, X.3
Lee, S.4
Hibar, D.P.5
Leow, A.D.6
Dinov, I.D.7
Toga, A.W.8
Saykin, A.J.9
Shen, L.10
Foroud, T.11
Pankratz, N.12
Huentelman, M.J.13
Craig, D.W.14
Gerber, J.D.15
Allen, A.N.16
Corneveaux, J.J.17
Stephan, D.A.18
Decarli, C.S.19
Dechairo, B.M.20
Potkin, S.G.21
Jack Jr., C.R.22
Weiner, M.W.23
Raji, C.A.24
Lopez, O.L.25
Becker, J.T.26
Carmichael, O.T.27
Thompson, P.M.28
more..
-
13
-
-
29044449855
-
Risk of dementia in diabetes mellitus: A systematic review
-
DOI 10.1016/S1474-4422(05)70284-2, PII S1474442205702842
-
Biessels GJ, Staekenborg S, Brunner E, Brayne C, Scheltens P (2006) Risk of dementia in diabetes mellitus: a systematic review. Lancet Neurol 5, 64-74. (Pubitemid 41790697)
-
(2006)
Lancet Neurology
, vol.5
, Issue.1
, pp. 64-74
-
-
Biessels, G.J.1
Staekenborg, S.2
Brunner, E.3
Brayne, C.4
Scheltens, P.5
-
14
-
-
72549091935
-
Association of plasma leptin levels with incident Alzheimer disease and MRI measures of brain aging
-
Lieb W, Beiser AS, Vasan RS, Tan ZS, Au R, Harris TB, Roubenoff R, Auerbach S, DeCarli C, Wolf PA, Seshadri S (2009) Association of plasma leptin levels with incident Alzheimer disease and MRI measures of brain aging. JAMA 302, 2565-2572.
-
(2009)
JAMA
, vol.302
, pp. 2565-2572
-
-
Lieb, W.1
Beiser, A.S.2
Vasan, R.S.3
Tan, Z.S.4
Au, R.5
Harris, T.B.6
Roubenoff, R.7
Auerbach, S.8
Decarli, C.9
Wolf, P.A.10
Seshadri, S.11
-
15
-
-
0026701491
-
Clinical diagnosis of Alzheimer's disease and other dementias in a population survey. Agreement and causes of disagreement in applying Diagnostic and Statistical Manual of Mental Disorders, Revised Third Edition, Criteria
-
Fratiglioni L, Grut M, Forsell Y, Viitanen M, Winblad B (1992) Clinical diagnosis of Alzheimer's disease and other dementias in a population survey. Agreement and causes of disagreement in applying Diagnostic and Statistical Manual of Mental Disorders, Revised Third Edition, Criteria. Arch Neurol 49, 927-932.
-
(1992)
Arch Neurol
, vol.49
, pp. 927-932
-
-
Fratiglioni, L.1
Grut, M.2
Forsell, Y.3
Viitanen, M.4
Winblad, B.5
-
16
-
-
30844436811
-
Mental, physical and social components in leisure activities equally contribute to decrease dementia risk
-
DOI 10.1159/000089919
-
Karp A, Paillard-Borg S,Wang HX, Silverstein M,Winblad B, Fratiglioni L (2006) Mental, physical and social components in leisure activities equally contribute to decrease dementia risk. Dement Geriatr Cogn Disord 21, 65-73. (Pubitemid 43107131)
-
(2006)
Dementia and Geriatric Cognitive Disorders
, vol.21
, Issue.2
, pp. 65-73
-
-
Karp, A.1
Paillard-Borg, S.2
Wang, H.-X.3
Silverstein, M.4
Winblad, B.5
Fratiglioni, L.6
-
18
-
-
0007601432
-
Epidemiology of Alzheimer's disease: The Kungsholmen Project
-
Fratiglioni L (1999) Epidemiology of Alzheimer's disease: The Kungsholmen Project. Neurol Rev Int 3, 12-15.
-
(1999)
Neurol Rev Int
, vol.3
, pp. 12-15
-
-
Fratiglioni, L.1
-
19
-
-
0031024278
-
Very old women at highest risk of dementia and Alzheimer's disease: Incidence data from the Kungsholmen Project, Stockholm
-
Fratiglioni L, Viitanen M, von Strauss E, Tontodonati V, Herlitz A,Winblad B (1997), Very old women at highest risk of dementia and Alzheimer's disease: incidence data from the Kungsholmen Project, Stockholm. Neurology 48, 132-138. (Pubitemid 27039531)
-
(1997)
Neurology
, vol.48
, Issue.1
, pp. 132-138
-
-
Fratiglioni, L.1
Viitanen, M.2
Von Strauss, E.3
Tontodonati, V.4
Herlitz, A.5
Winblad, B.6
-
20
-
-
5344237420
-
Diabetes mellitus and risk of dementia in the Kungsholmen project: A 6-year follow-up study
-
Xu WL, Qiu CX, Wahlin A, Winblad B, Fratiglioni L (2004) Diabetes mellitus and risk of dementia in the Kungsholmen project: a 6-year follow-up study. Neurology 63, 1181-1186. (Pubitemid 39350014)
-
(2004)
Neurology
, vol.63
, Issue.7
, pp. 1181-1186
-
-
Xu, W.L.1
Qiu, C.X.2
Wahlin, A.3
Winblad, B.4
Fratiglioni, L.5
-
21
-
-
67349085203
-
Uncontrolled diabetes increases the risk of Alzheimer's disease: A population-based cohort study
-
Xu WL, von Strauss E, Qiu CX, Winblad B, Fratiglioni L (2009) Uncontrolled diabetes increases the risk of Alzheimer's disease: a population-based cohort study. Diabetologia 52, 1031-1039.
-
(2009)
Diabetologia
, vol.52
, pp. 1031-1039
-
-
Xu, W.L.1
Von Strauss, E.2
Qiu, C.X.3
Winblad, B.4
Fratiglioni, L.5
-
22
-
-
0029845764
-
Apolipoprotein E polymorphism and stroke in a population sample aged 75 years or more
-
Basun H, Corder EH, Guo Z, Lannfelt L, Corder LS, Manton KG, Winblad B, Viitanen M (1996) Apolipoprotein E polymorphism and stroke in a population sample aged 75 years or more. Stroke 27, 1310-1315. (Pubitemid 26286159)
-
(1996)
Stroke
, vol.27
, Issue.8
, pp. 1310-1315
-
-
Basun, H.1
Corder, E.H.2
Guo, Z.3
Lannfelt, L.4
Corder, L.S.5
Manton, K.G.6
Winblad, B.7
Viitanen, M.8
-
23
-
-
34249745769
-
GAB2 Alleles Modify Alzheimer's Risk in APOE ε4 Carriers
-
DOI 10.1016/j.neuron.2007.05.022, PII S0896627307003790
-
Reiman EM, Webster JA, Myers AJ, Hardy J, Dunckley T, Zismann VL, Joshipura KD, Pearson JV, Hu-Lince D, Huentelman MJ, Craig DW, Coon KD, Liang WS, Herbert RH, Beach T, Rohrer KC, Zhao AS, Leung D, Bryden L, Marlowe L, Kaleem M, Mastroeni D, Grover A, Heward CB, Ravid R, Rogers J, Hutton ML, Melquist S, Petersen RC, Alexander GE, Caselli RJ, Kukull W, Papassotiropoulos A, Stephan DA (2007) GAB2 alleles modify Alzheimer's risk in APOE epsilon4 carriers. Neuron 54, 713-720. (Pubitemid 46843528)
-
(2007)
Neuron
, vol.54
, Issue.5
, pp. 713-720
-
-
Reiman, E.M.1
Webster, J.A.2
Myers, A.J.3
Hardy, J.4
Dunckley, T.5
Zismann, V.L.6
Joshipura, K.D.7
Pearson, J.V.8
Hu-Lince, D.9
Huentelman, MatthewJ.10
Craig, D.W.11
Coon, K.D.12
Liang, W.S.13
Herbert, R.H.14
Beach, T.15
Rohrer, K.C.16
Zhao, A.S.17
Leung, D.18
Bryden, L.19
Marlowe, L.20
Kaleem, M.21
Mastroeni, D.22
Grover, A.23
Heward, C.B.24
Ravid, R.25
Rogers, J.26
Hutton, M.L.27
Melquist, S.28
Petersen, R.C.29
Alexander, G.E.30
Caselli, RichardJ.31
Kukull, W.32
Papassotiropoulos, A.33
Stephan, D.A.34
more..
-
24
-
-
70349558522
-
Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease
-
Harold D, Abraham R, Hollingworth P, Sims R, Gerrish A, Hamshere ML, Pahwa JS, Moskvina V, Dowzell K,Williams A, Jones N, Thomas C, Stretton A, Morgan AR, Lovestone S, Powell J, Proitsi P, Lupton MK, Brayne C, Rubinsztein DC, Gill M, Lawlor B, Lynch A, Morgan K, Brown KS, Passmore PA, Craig D, McGuinness B, Todd S, Holmes C, Mann D, Smith AD, Love S, Kehoe PG, Hardy J, Mead S, Fox N, Rossor M, Collinge J, Maier W, Jessen F, Schurmann B, van den Bussche H, Heuser I, Kornhuber J, Wiltfang J, Dichgans M, Frolich L, Hampel H, Hull M, Rujescu D, Goate AM, Kauwe JS, Cruchaga C, Nowotny P, Morris JC, Mayo K, Sleegers K, Bettens K, Engelborghs S, De Deyn PP, Van BroeckhovenC,Livingston G, Bass NJ, Gurling H, McQuillin A, Gwilliam R, Deloukas P, Al-Chalabi A, Shaw CE, Tsolaki M, Singleton AB, Guerreiro R, Muhleisen TW, Nothen MM, Moebus S, Jockel KH, Klopp N,Wichmann HE, Carrasquillo MM, Pankratz VS, Younkin SG, Holmans PA, O'Donovan M, Owen MJ, Williams J (2009) Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease. Nat Genet 41, 1088-1093.
-
(2009)
Nat Genet
, vol.41
, pp. 1088-1093
-
-
Harold, D.1
Abraham, R.2
Hollingworth, P.3
Sims, R.4
Gerrish, A.5
Hamshere, M.L.6
Pahwa, J.S.7
Moskvina, V.8
Dowzell Kwilliams, A.9
Jones, N.10
Thomas, C.11
Stretton, A.12
Morgan, A.R.13
Lovestone, S.14
Powell, J.15
Proitsi, P.16
Lupton, M.K.17
Brayne, C.18
Rubinsztein, D.C.19
Gill, M.20
Lawlor, B.21
Lynch, A.22
Morgan, K.23
Brown, K.S.24
Passmore, P.A.25
Craig, D.26
McGuinness, B.27
Todd, S.28
Holmes, C.29
Mann, D.30
Smith, A.D.31
Love, S.32
Kehoe, P.G.33
Hardy, J.34
Mead, S.35
Fox, N.36
Rossor, M.37
Collinge, J.38
Maier, W.39
Jessen, F.40
Schurmann, B.41
Van Den Bussche, H.42
Heuser, I.43
Kornhuber, J.44
Wiltfang, J.45
Dichgans, M.46
Frolich, L.47
Hampel, H.48
Hull, M.49
Rujescu, D.50
Goate, A.M.51
Kauwe, J.S.52
Cruchaga, C.53
Nowotny, P.54
Morris, J.C.55
Mayo, K.56
Sleegers, K.57
Bettens, K.58
Engelborghs, S.59
De Deyn, P.P.60
Van Broeckhoven, C.61
Livingston, G.62
Bass, N.J.63
Gurling, H.64
McQuillin, A.65
Gwilliam, R.66
Deloukas, P.67
Al-Chalabi, A.68
Shaw, C.E.69
Tsolaki, M.70
Singleton, A.B.71
Guerreiro, R.72
Muhleisen, T.W.73
Nothen, M.M.74
Moebus, S.75
Jockel, K.H.76
Klopp Nwichmann, H.E.77
Carrasquillo, M.M.78
Pankratz, V.S.79
Younkin, S.G.80
Holmans, P.A.81
O'Donovan, M.82
Owen, M.J.83
Williams, J.84
more..
-
25
-
-
78549264026
-
Genome-wide association study identifies variants atCLUandCR1associated with Alzheimer's disease
-
Lambert JC, Heath S, Even G, Campion D, Sleegers K, Hiltunen M, Combarros O, Zelenika D, Bullido MJ, Tavernier B, Letenneur L, Bettens K, Berr C, Pasquier F, Fievet N, Barberger-Gateau P, Engelborghs S, De Deyn P, Mateo I, Franck A, Helisalmi S, Porcellini E, Hanon O, de Pancorbo MM,Lendon C, Dufouil C, Jaillard C, LeveillardT, AlvarezV, Bosco P, Mancuso M, Panza F, Nacmias B, Bossu P, Piccardi P, Annoni G, Seripa D, Galimberti D, Hannequin D, Licastro F, Soininen H, Ritchie K, Blanche H, Dartigues JF, Tzourio C, Gut I, Van Broeckhoven C, Alperovitch A, Lathrop M, Amouyel P (2009) Genome-wide association study identifies variants atCLUandCR1associated with Alzheimer's disease. Nat Genet 41, 1094-1099.
-
(2009)
Nat Genet
, vol.41
, pp. 1094-1099
-
-
Lambert, J.C.1
Heath, S.2
Even, G.3
Campion, D.4
Sleegers, K.5
Hiltunen, M.6
Combarros, O.7
Zelenika, D.8
Bullido, M.J.9
Tavernier, B.10
Letenneur, L.11
Bettens, K.12
Berr, C.13
Pasquier, F.14
Fievet, N.15
Barberger-Gateau, P.16
Engelborghs, S.17
De Deyn, P.18
Mateo, I.19
Franck, A.20
Helisalmi, S.21
Porcellini, E.22
Hanon, O.23
De Pancorbo Mmlendon, C.24
Dufouil, C.25
Jaillard, C.26
Alvarezv, L.27
Bosco, P.28
Mancuso, M.29
Panza, F.30
Nacmias, B.31
Bossu, P.32
Piccardi, P.33
Annoni, G.34
Seripa, D.35
Galimberti, D.36
Hannequin, D.37
Licastro, F.38
Soininen, H.39
Ritchie, K.40
Blanche, H.41
Dartigues, J.F.42
Tzourio, C.43
Gut, I.44
Van Broeckhoven, C.45
Alperovitch, A.46
Lathrop, M.47
Amouyel, P.48
more..
-
26
-
-
58149340093
-
Fat mass-and obesity-associated (FTO) gene variant is associated with obesity: Longitudinal analyses in two cohort studies and functional test
-
Qi L, Kang K, Zhang C, van Dam RM, Kraft P, Hunter D, Lee CH, Hu FB (2008) Fat mass-and obesity-associated (FTO) gene variant is associated with obesity: longitudinal analyses in two cohort studies and functional test. Diabetes 57, 3145-3151.
-
(2008)
Diabetes
, vol.57
, pp. 3145-3151
-
-
Qi, L.1
Kang, K.2
Zhang, C.3
Van Dam, R.M.4
Kraft, P.5
Hunter, D.6
Lee, C.H.7
Hu, F.B.8
-
27
-
-
84887212356
-
Fatnessassociated FTO gene variant increases mortality independent of fatness-in cohorts of Danish men
-
Zimmermann E, Kring SI, Berentzen TL, Holst C, Pers TH, Hansen T, Pedersen O, Sorensen TI, Jess T (2009) Fatnessassociated FTO gene variant increases mortality independent of fatness-in cohorts of Danish men. PLoS ONE 4, e4428.
-
(2009)
PLoS ONE
, vol.4
-
-
Zimmermann, E.1
Kring, S.I.2
Berentzen, T.L.3
Holst, C.4
Pers, T.H.5
Hansen, T.6
Pedersen, O.7
Sorensen, T.I.8
Jess, T.9
-
28
-
-
35848938196
-
Variation in the FTO gene locus is associated with cerebrocortical insulin resistance in humans [2]
-
DOI 10.1007/s00125-007-0839-1
-
Tschritter O, Preissl H, Yokoyama Y, Machicao F, Haring HU, Fritsche A (2007) Variation in the FTO gene locus is associated with cerebrocortical insulin resistance in humans. Diabetologia. 50, 2602-2603. (Pubitemid 350060655)
-
(2007)
Diabetologia
, vol.50
, Issue.12
, pp. 2602-2603
-
-
Tschritter, O.1
Preissl, H.2
Yokoyama, Y.3
Machicao, F.4
Haring, H.-U.5
Fritsche, A.6
-
29
-
-
67649875640
-
Loss-offunction mutation in the dioxygenase-encoding FTO gene causes severe growth retardation and multiple malformations
-
Boissel S, Reish O, Proulx K, Kawagoe-Takaki H, Sedgwick B, Yeo GS, Meyre D, Golzio C, Molinari F, Kadhom N, Etchevers HC, Saudek V, Farooqi IS, Froguel P, Lindahl T, O'Rahilly S, Munnich A, Colleaux L (2009) Loss-offunction mutation in the dioxygenase-encoding FTO gene causes severe growth retardation and multiple malformations. Am J Hum Genet 85, 106-111.
-
(2009)
Am J Hum Genet
, vol.85
, pp. 106-111
-
-
Boissel, S.1
Reish, O.2
Proulx, K.3
Kawagoe-Takaki, H.4
Sedgwick, B.5
Yeo, G.S.6
Meyre, D.7
Golzio, C.8
Molinari, F.9
Kadhom, N.10
Etchevers, H.C.11
Saudek, V.12
Farooqi, I.S.13
Froguel, P.14
Lindahl, T.15
O'Rahilly, S.16
Munnich, A.17
Colleaux, L.18
-
30
-
-
26844483210
-
Leisure-time physical activity at midlife and the risk of dementia and Alzheimer's disease
-
DOI 10.1016/S1474-4422(05)70198-8, PII S1474442205701988
-
Rovio S, Kareholt I, Helkala EL, Viitanen M, Winblad B, Tuomilehto J, Soininen H, Nissinen A, Kivipelto M (2005) Leisure-time physical activity at midlife and the risk of dementia and Alzheimer's disease. Lancet Neurol 4, 705-711. (Pubitemid 41457285)
-
(2005)
Lancet Neurology
, vol.4
, Issue.11
, pp. 705-711
-
-
Rovio, S.1
Kareholt, I.2
Helkala, E.-L.3
Viitanen, M.4
Winblad, B.5
Tuomilehto, J.6
Soininen, H.7
Nissinen, A.8
Kivipelto, M.9
-
31
-
-
51649128621
-
Obesity associated genetic variation in FTO is associated with diminished satiety
-
Wardle J, Carnell S, Haworth CM, Farooqi IS, O'Rahilly S, Plomin R (2008) Obesity associated genetic variation in FTO is associated with diminished satiety. J Clin Endocrinol Metab 93, 3640-3643.
-
(2008)
J Clin Endocrinol Metab
, vol.93
, pp. 3640-3643
-
-
Wardle, J.1
Carnell, S.2
Haworth, C.M.3
Farooqi, I.S.4
O'Rahilly, S.5
Plomin, R.6
-
32
-
-
33745191471
-
Fat intake at midlife and risk of dementia and Alzheimer's disease: A population-based study
-
Laitinen MH, Ngandu T, Rovio S, Helkala EL, Uusitalo U, Viitanen M, Nissinen A, Tuomilehto J, Soininen H, Kivipelto M (2006) Fat intake at midlife and risk of dementia and Alzheimer's disease: a population-based study. Dement Geriatr Cogn Disord 22, 99-107.
-
(2006)
Dement Geriatr Cogn Disord
, vol.22
, pp. 99-107
-
-
Laitinen, M.H.1
Ngandu, T.2
Rovio, S.3
Helkala, E.L.4
Uusitalo, U.5
Viitanen, M.6
Nissinen, A.7
Tuomilehto, J.8
Soininen, H.9
Kivipelto, M.10
|