Inverse association of the obesity predisposing FTO rs9939609 genotype with alcohol consumption and risk for alcohol dependence

Addiction

Volumn 106, Issue 4, 2011, Pages 739-748

  Sobczyk Kopciol, Agnieszka ^a   Broda, Grazyna ^b   Wojnar, Marcin ^a,c   Kurjata, Pawel ^b   Jakubczyk, Andrzej ^a   Klimkiewicz, Anna ^a   Ploski, Rafal ^a  

^a MEDICAL UNIVERSITY OF WARSAW   (Poland)

^b INSTITUTE OF CARDIOLOGY   (Poland)

^c UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

Author keywords

Alcohol; Dependence; FTO; Genetics; Obesity; Smoking; Tobacco

Indexed keywords

FTO PROTEIN, HUMAN; PROTEIN;

ADULT; AGED; ALCOHOLIC BEVERAGE; ALCOHOLISM; ARTICLE; BODY MASS; BODY WEIGHT; CLASSIFICATION; CLINICAL TRIAL; DRINKING BEHAVIOR; EPIDEMIOLOGY; FEMALE; GENETIC PREDISPOSITION; GENETICS; GENOTYPE; HUMAN; MALE; MIDDLE AGED; MULTICENTER STUDY; OBESITY; ONSET AGE; POLAND; POLYMERASE CHAIN REACTION; SMOKING; UTILIZATION REVIEW; WAIST CIRCUMFERENCE;

ADULT; AGE OF ONSET; AGED; ALCOHOL DRINKING; ALCOHOLIC BEVERAGES; ALCOHOLISM; BODY MASS INDEX; BODY WEIGHT; EPIDEMIOLOGIC METHODS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; MALE; MIDDLE AGED; OBESITY; POLAND; POLYMERASE CHAIN REACTION; PROTEINS; SMOKING; WAIST CIRCUMFERENCE; YOUNG ADULT;

EID: 79952305733     PISSN: 09652140     EISSN: 13600443     Source Type: Journal    
DOI: 10.1111/j.1360-0443.2010.03248.x     Document Type: Article

References (51)

1. Kalsi G., Prescott C. A., Kendler K. S., Riley B. P. Unraveling the molecular mechanisms of alcohol dependence. Trends Genet 2009; 25: 49-55.
2. Frayling T. M., Timpson N. J., Weedon M. N., Zeggini E., Freathy R. M., Lindgren C. M. etal. A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. Science 2007; 316: 889-94.
3. Hinney A., Vogel C. I., Hebebrand J. From monogenic to polygenic obesity: recent advances. Eur Child Adolesc Psychiatry 2010; 19: 297-310.
4. Cecil J. E., Tavendale R., Watt P., Hetherington M. M., Palmer C. N. A. An obesity-associated FTO gene variant and increased energy intake in children. N Engl J Med 2008; 359: 2558-66.
5. Wahlen K., Sjolin E., Hoffstedt J. The common rs9939609 gene variant of the fat mass- and obesity-associated gene FTO is related to fat cell lipolysis. J Lipid Res 2008; 49: 607-11.
6. Fischer J., Koch L., Emmerling C., Vierkotten J., Peters T., Bruning J. C. etal. Inactivation of the Fto gene protects from obesity. Nature 2009; 458: 894-8.
7. Speakman J. R., Rance K. A., Johnstone A. M. Polymorphisms of the FTO gene are associated with variation in energy intake, but not energy expenditure. Obesity 2008; 16: 1961-5.
8. Timpson N. J., Emmett P. M., Frayling T. M., Rogers I., Hattersley A. T., McCarthy M. I. etal. The fat mass- and obesity-associated locus and dietary intake in children. Am J Clin Nutr 2008; 88: 971-8.
9. Wardle J., Carnell S., Haworth C. M., Farooqi I. S., O'Rahilly S., Plomin R. Obesity associated genetic variation in FTO is associated with diminished satiety. J Clin Endocrinol Metab 2008; 93: 3640-3.
10. Wardle J., Llewellyn C., Sanderson S., Plomin R. The FTO gene and measured food intake in children. Int J Obes 2008; 33: 42-5.
11. den Hoed M., Westerterp-Plantenga M. S., Bouwman F. G., Mariman E. C., Westerterp K. R. Postprandial responses in hunger and satiety are associated with the rs9939609 single nucleotide polymorphism in FTO. Am J Clin Nutr 2009; 90: 1426-32.
12. Haupt A., Thamer C., Staiger H., Tschritter O., Kirchhoff K., Machicao F. etal. Variation in the FTO gene influences food intake but not energy expenditure. Exp Clin Endocrinol Diabetes 2009; 117: 194-7.
13. Tanofsky-Kraff M., Han J. C., Anandalingam K., Shomaker L. B., Columbo K. M., Wolkoff L. E. etal. The FTO gene rs9939609 obesity-risk allele and loss of control over eating. Am J Clin Nutr 2009; 90: 1483-8.
14. Barry D., Clarke M., Petry N. M. Obesity and its relationship to addictions: is overeating a form of addictive behavior. Am J Addict 2009; 18: 439-51.
15. Galanti K., Gluck M. E., Geliebter A. Test meal intake in obese binge eaters in relation to impulsivity and compulsivity. Int J Eat Disord 2007; 40: 727-32.
16. Davis C., Levitan R. D., Muglia P., Bewell C., Kennedy J. L. Decision-making deficits and overeating: a risk model for obesity. Obes Res 2004; 12: 929-35.
17. Dom G., D'haene P., Hulstijn W., Sabbe B. Impulsivity in abstinent early- and late-onset alcoholics: differences in self-report measures and a discounting task. Addiction 2006; 101: 50-9.
18. Trinko R., Sears R. M., Guarnieri D. J., DiLeone R. J. Neural mechanisms underlying obesity and drug addiction. Physiol Behav 2007; 91: 499-505.
19. Istvan J., Murray R., Voelker H. The relationship between patterns of alcohol consumption and body weight. Lung Health Study Research Group. Int J Epidemiol 1995; 24: 543-6.
20. Dorn J. M., Hovey K., Muti P., Freudenheim J. L., Russell M., Nochajski T. H. etal. Alcohol drinking patterns differentially affect central adiposity as measured by abdominal height in women and men. J Nutr 2003; 133: 2655-62.
21. Tolstrup J. S., Heitmann B. L., Tjonneland A. M., Overvad O. K., Sorensen T. I., Gronbaek M. N. The relation between drinking pattern and body mass index and waist and hip circumference. Int J Obes (Lond) 2005; 29: 490-7.
22. Kauhanen J., Kaplan G. A., Goldberg D. E., Salonen R., Salonen J. T. Pattern of alcohol drinking and progression of atherosclerosis. Arterioscler Thromb Vasc Biol 1999; 19: 3001-6.
23. O'Keefe J. H., Bybee K. A., Lavie C. J. Alcohol and cardiovascular health: the razor-sharp double-edged sword. J Am Coll Cardiol 2007; 50: 1009-14.
24. Buemann B., Astrup A. How does the body deal with energy from alcohol? Nutrition 2001; 17: 638-41.
25. Lands W. E., Zakhari S. The case of the missing calories. Am J Clin Nutr 1991; 54: 47-8.
26. Badaoui A., De Saeger C., Duchemin J., Gihousse D., de Timary P., Starkel P. Alcohol dependence is associated with reduced plasma and fundic ghrelin levels. Eur J Clin Invest 2008; 38: 397-403.
27. Duncan B. B., Chambless L. E., Schmidt M. I., Folsom A. R., Szklo M., Crouse J. R. etal. Association of the waist-to-hip ratio is different with wine than with beer or hard liquor consumption. Atherosclerosis Risk in Communities Study Investigators. Am J Epidemiol 1995; 142: 1034-8.
28. Lapidus L., Bengtsson C., Hallstrom T., Bjorntorp P. Obesity, adipose tissue distribution and health in women-results from a population study in Gothenburg, Sweden. Appetite 1989; 13: 25-35.
29. Slattery M. L., McDonald A., Bild D. E., Caan B. J., Hilner J. E., Jacobs D. R. etal. Associations of body fat and its distribution with dietary intake, physical activity, alcohol, and smoking in blacks and whites. Am J Clin Nutr 1992; 55: 943-9.
30. Wannamethee S. G., Shaper A. G., Whincup P. H. Alcohol and adiposity: effects of quantity and type of drink and time relation with meals. Int J Obes (Lond) 2005; 29: 1436-44.
31. Dallongeville J., Marecaux N., Ducimetiere P., Ferrieres J., Arveiler D., Bingham A. etal. Influence of alcohol consumption and various beverages on waist girth and waist-to-hip ratio in a sample of French men and women. Int J Obes Relat Metab Disord 1998; 22: 1178-83.
32. Rosmond R., Bjorntorp P. Psychosocial and socio-economic factors in women and their relationship to obesity and regional body fat distribution. Int J Obes Relat Metab Disord 1999; 23: 138-45.
33. Bobak M., Skodova Z., Marmot M. Beer and obesity: a cross-sectional study. Eur J Clin Nutr 2003; 57: 1250-3.
34. Kostrzewa G., Broda G., Kurjata P., Piotrowski W., Ploski R. Effect of protein convertase subtilisin/kexin type 9 (PCSK9) 46L gene polymorphism on LDL cholesterol concentration in a Polish adult population. Mol Genet Metab 2008; 94: 259-62.
35. Broda G., Rywik S. Multi-center all-polish health survey-WOBASZ project. Defining the Problem and Aims of the Study. Pol Popul Rev 2005; 27: 29-36.
36. Rywik S., Kupsc W., Piotrowski W., Broda G. Multi-center all-Polish health survey-WOBASZ project. Methodological assumptions and logistics. Pol Popul Rev 2005; 27: 37-50.
37. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, 4th edn, text revised. Washington, DC: American Psychiatric Association; 2000.
38. Wojnar M., Ilgen M. A., Jakubczyk A., Wnorowska A., Klimkiewicz A., Brower K. J. Impulsive suicide attempts predict post-treatment relapse in alcohol-dependent patients. Drug Alcohol Depend 2008; 97: 268-75.
39. Wojnar M., Brower K. J., Strobbe S., Ilgen M., Matsumoto H., Nowosad I. etal. Association between Val66Met brain-derived neurotrophic factor (BDNF) gene polymorphism and post-treatment relapse in alcohol dependence. Alcohol Clin Exp Res 2009; 33: 693-702.
40. Ye S., Humphries S., Green F. Allele specific amplification by tetra-primer PCR. Nucleic Acids Res 1992; 20: 1152.
41. Kleiner K. D., Gold M. S., Frost-Pineda K., Lenz-Brunsman B., Perri M. G., Jacobs W. S. Body mass index and alcohol use. J Addict Dis 2004; 23: 105-18.
42. McCarty M. F. The alcohol paradox. Am J Clin Nutr 1999; 70: 940-1.
43. Suter P. M. The paradox of the alcohol-paradox-another step towards the resolution of the 'alcohol energy wastage' controversy. Eur J Clin Invest 2000; 30: 749-50.
44. Yeomans M. R. Alcohol, appetite and energy balance: is alcohol intake a risk factor for obesity. Physiol Behav 2010; 100: 82-9.
45. Arif A., Rohrer J. Patterns of alcohol drinking and its association with obesity: data from the third national health and nutrition examination survey, 1988-1994. BMC Public Health 2005; 5: 126.
46. Breslow R. A., Smothers B. A. Drinking patterns and body mass index in never smokers: National Health Interview Survey, 1997-2001. Am J Epidemiol 2005; 161: 368-76.
47. Jequier E. Alcohol intake and body weight: a paradox. Am J Clin Nutr 1999; 69: 173-4.
48. Ploski R., Wozniak M., Pawlowski R., Monies D. M., Branicki W., Kupiec T. etal. Homogeneity and distinctiveness of Polish paternal lineages revealed by Y chromosome microsatellite haplotype analysis. Hum Genet 2002; 110: 592-600.
49. Hennig B. J., Fulford A. J., Sirugo G., Rayco-Solon P., Hattersley A. T., Frayling T. M. etal. FTO gene variation and measures of body mass in an African population. BMC Med Genet 2009; 10: 21.
50. Scott R. A., Bailey M. E., Moran C. N., Wilson R. H., Fuku N., Tanaka M. etal. FTO genotype and adiposity in children: physical activity levels influence the effect of the risk genotype in adolescent males. Eur J Hum Genet 2010.
51. Feunekes G. I. J., van't Veer P., van Staveren W. A., Kok F. J. Alcohol intake assessment: the sober facts. Am J Epidemiol 1999; 150: 105-12.