Cell-Autonomous Progeroid Changes in Conditional Mouse Models for Repair Endonuclease XPG Deficiency

PLoS Genetics

Volumn 10, Issue 10, 2014, Pages

  Barnhoorn, Sander ^a   Uittenboogaard, Lieneke M ^a   Jaarsma, Dick ^a   Vermeij, Wilbert P ^a   Tresini, Maria ^a   Weymaere, Michael ^a   Menoni, Hervé ^a   Brandt, Renata M C ^a   de Waard, Monique C ^b   Botter, Sander M ^c   Sarker, Altaf H ^d   Jaspers, Nicolaas G J ^a   van der Horst, Gijsbertus T J ^a   Cooper, Priscilla K ^d   Hoeijmakers, Jan H J ^a   van der Pluijm, Ingrid ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^c BALGRIST UNIVERSITY HOSPITAL   (Switzerland)

^d LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENDONUCLEASE; UNCLASSIFIED DRUG; XPG PROTEIN; DNA BINDING PROTEIN; DNA EXCISION REPAIR PROTEIN ERCC-5; NUCLEAR PROTEIN; TRANSCRIPTION FACTOR;

AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CACHEXIA; CELL LOSS; DNA DAMAGE; DNA REPAIR; EMBRYO; ENZYME DEFICIENCY; FEMALE; GENE DELETION; GENETIC DISORDER; HUMAN; HUMAN CELL; HYBRID GENE; KYPHOSIS; LIFESPAN; LIPOLYSIS; LIVER FATTY DEGENERATION; MALE; MOUSE; MOUSE MODEL; NERVE DEGENERATION; NONHUMAN; OSTEOPOROSIS; PHENOTYPE; PHOTORECEPTOR CELL; PROGEROID DISORDER; WEIGHT REDUCTION; XPG GENE; ANIMAL; BRAIN; C57BL MOUSE; CENTRAL NERVOUS SYSTEM; DEFICIENCY; DEFICIENCY DISEASES; DISEASE MODEL; GENETICS; LIVER; LONGEVITY; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; PREGNANCY; TRANSGENIC MOUSE;

AGING; ANIMALS; BRAIN; CACHEXIA; CENTRAL NERVOUS SYSTEM; DEFICIENCY DISEASES; DISEASE MODELS, ANIMAL; DNA REPAIR; DNA-BINDING PROTEINS; ENDONUCLEASES; FEMALE; LIVER; LONGEVITY; MALE; MICE, INBRED C57BL; MICE, TRANSGENIC; NUCLEAR PROTEINS; OSTEOPOROSIS; PREGNANCY; TRANSCRIPTION FACTORS;

EID: 84908333668     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1004686     Document Type: Article

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