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Volumn 120, Issue 4, 2010, Pages 461-475

Age-related motor neuron degeneration in DNA repair-deficient Ercc1 mice

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 3; EXCISION REPAIR CROSS COMPLEMENTING PROTEIN 1; PROTEIN P53;

EID: 77956189163     PISSN: 00016322     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00401-010-0715-9     Document Type: Article
Times cited : (84)

References (70)
  • 1
    • 49449084673 scopus 로고    scopus 로고
    • ERCC1-XPF endonuclease facilitates DNA double-strand break repair
    • 10.1128/MCB.00293-08 18541667
    • A Ahmad AR Robinson A Duensing, et al. 2008 ERCC1-XPF endonuclease facilitates DNA double-strand break repair Mol Cell Biol 28 5082 5092 10.1128/MCB.00293-08 18541667
    • (2008) Mol Cell Biol , vol.28 , pp. 5082-5092
    • Ahmad, A.1    Robinson, A.R.2    Duensing, A.3
  • 2
    • 77950455401 scopus 로고    scopus 로고
    • Mislocalization of XPF-ERCC1 nuclease contributes to reduced DNA repair in XP-F patients
    • 10.1371/journal.pgen.1000871 20221251
    • A Ahmad JH Enzlin NR Bhagwat, et al. 2010 Mislocalization of XPF-ERCC1 nuclease contributes to reduced DNA repair in XP-F patients PLoS Genet 6 e1000871 10.1371/journal.pgen.1000871 20221251
    • (2010) PLoS Genet , vol.6 , pp. 1000871
    • Ahmad, A.1    Enzlin, J.H.2    Bhagwat, N.R.3
  • 3
    • 45449115731 scopus 로고    scopus 로고
    • Cytotoxicity and mutagenicity of endogenous DNA base lesions as potential cause of human aging
    • 10.1016/j.mad.2008.01.007 18355895
    • M Akbari HE Krokan 2008 Cytotoxicity and mutagenicity of endogenous DNA base lesions as potential cause of human aging Mech Ageing Dev 129 353 365 10.1016/j.mad.2008.01.007 18355895
    • (2008) Mech Ageing Dev , vol.129 , pp. 353-365
    • Akbari, M.1    Krokan, H.E.2
  • 4
    • 3142559735 scopus 로고    scopus 로고
    • Molecular basis for Golgi maintenance and biogenesis
    • 10.1016/j.ceb.2004.06.011 15261668
    • N Altan-Bonnet R Sougrat J Lippincott-Schwartz 2004 Molecular basis for Golgi maintenance and biogenesis Curr Opin Cell Biol 16 364 372 10.1016/j.ceb.2004.06.011 15261668
    • (2004) Curr Opin Cell Biol , vol.16 , pp. 364-372
    • Altan-Bonnet, N.1    Sougrat, R.2    Lippincott-Schwartz, J.3
  • 5
    • 0025865829 scopus 로고
    • The kinetics and morphological characteristics of the macrophage-microglial response to kainic acid-induced neuronal degeneration
    • 10.1016/0306-4522(91)90159-L 1713656
    • PB Andersson VH Perry S Gordon 1991 The kinetics and morphological characteristics of the macrophage-microglial response to kainic acid-induced neuronal degeneration Neuroscience 42 201 214 10.1016/0306-4522(91)90159-L 1713656
    • (1991) Neuroscience , vol.42 , pp. 201-214
    • Andersson, P.B.1    Perry, V.H.2    Gordon, S.3
  • 6
    • 61749093727 scopus 로고    scopus 로고
    • An Xpb mouse model for combined xeroderma pigmentosum and cockayne syndrome reveals progeroid features upon further attenuation of DNA repair
    • 10.1128/MCB.01229-08 19114557
    • JO Andressoo G Weeda J de Wit, et al. 2009 An Xpb mouse model for combined xeroderma pigmentosum and cockayne syndrome reveals progeroid features upon further attenuation of DNA repair Mol Cell Biol 29 1276 1290 10.1128/MCB.01229-08 19114557
    • (2009) Mol Cell Biol , vol.29 , pp. 1276-1290
    • Andressoo, J.O.1    Weeda, G.2    De Wit, J.3
  • 7
    • 49449096533 scopus 로고    scopus 로고
    • Neurological symptoms and natural course of xeroderma pigmentosum
    • 10.1093/brain/awn126 18567921
    • A Anttinen L Koulu E Nikoskelainen, et al. 2008 Neurological symptoms and natural course of xeroderma pigmentosum Brain 131 1979 1989 10.1093/brain/awn126 18567921
    • (2008) Brain , vol.131 , pp. 1979-1989
    • Anttinen, A.1    Koulu, L.2    Nikoskelainen, E.3
  • 8
    • 44949085340 scopus 로고    scopus 로고
    • The role of the DNA damage response in neuronal development, organization and maintenance
    • 10.1016/j.dnarep.2008.03.005 18458000
    • A Barzilai S Biton Y Shiloh 2008 The role of the DNA damage response in neuronal development, organization and maintenance DNA Repair 7 1010 1027 10.1016/j.dnarep.2008.03.005 18458000
    • (2008) DNA Repair , vol.7 , pp. 1010-1027
    • Barzilai, A.1    Biton, S.2    Shiloh, Y.3
  • 9
    • 38549146496 scopus 로고    scopus 로고
    • Interstrand crosslink repair: Can XPF-ERCC1 be let off the hook?
    • 10.1016/j.tig.2007.11.003 18192062
    • DT Bergstralh J Sekelsky 2008 Interstrand crosslink repair: can XPF-ERCC1 be let off the hook? Trends Genet 24 70 76 10.1016/j.tig.2007.11.003 18192062
    • (2008) Trends Genet , vol.24 , pp. 70-76
    • Bergstralh, D.T.1    Sekelsky, J.2
  • 10
    • 71949083551 scopus 로고    scopus 로고
    • XPF-ERCC1 participates in the Fanconi anemia pathway of cross-link repair
    • 10.1128/MCB.00086-09 19805513
    • N Bhagwat AL Olsen AT Wang, et al. 2009 XPF-ERCC1 participates in the Fanconi anemia pathway of cross-link repair Mol Cell Biol 29 6427 6437 10.1128/MCB.00086-09 19805513
    • (2009) Mol Cell Biol , vol.29 , pp. 6427-6437
    • Bhagwat, N.1    Olsen, A.L.2    Wang, A.T.3
  • 11
    • 44949263779 scopus 로고    scopus 로고
    • The 8, 5′-cyclopurine-2′-deoxynucleosides: Candidate neurodegenerative DNA lesions in xeroderma pigmentosum, and unique probes of transcription and nucleotide excision repair
    • 10.1016/j.dnarep.2008.03.016 18495558
    • PJ Brooks 2008 The 8, 5′-cyclopurine-2′-deoxynucleosides: candidate neurodegenerative DNA lesions in xeroderma pigmentosum, and unique probes of transcription and nucleotide excision repair DNA Repair 7 1168 1179 10.1016/j.dnarep.2008.03.016 18495558
    • (2008) DNA Repair , vol.7 , pp. 1168-1179
    • Brooks, P.J.1
  • 12
    • 43849107357 scopus 로고    scopus 로고
    • Do all of the neurologic diseases in patients with DNA repair gene mutations result from the accumulation of DNA damage?
    • 10.1016/j.dnarep.2008.01.017 18339586
    • PJ Brooks TF Cheng L Cooper 2008 Do all of the neurologic diseases in patients with DNA repair gene mutations result from the accumulation of DNA damage? DNA Repair 7 834 848 10.1016/j.dnarep.2008.01.017 18339586
    • (2008) DNA Repair , vol.7 , pp. 834-848
    • Brooks, P.J.1    Cheng, T.F.2    Cooper, L.3
  • 13
    • 21044448079 scopus 로고    scopus 로고
    • Two separate motifs cooperate to target stathmin-related proteins to the Golgi complex
    • 10.1242/jcs.02349 15870110
    • E Charbaut S Chauvin H Enslen, et al. 2005 Two separate motifs cooperate to target stathmin-related proteins to the Golgi complex J Cell Sci 118 2313 2323 10.1242/jcs.02349 15870110
    • (2005) J Cell Sci , vol.118 , pp. 2313-2323
    • Charbaut, E.1    Chauvin, S.2    Enslen, H.3
  • 14
    • 2442658908 scopus 로고    scopus 로고
    • DNA/RNA helicase gene mutations in a form of juvenile amyotrophic lateral sclerosis (ALS4)
    • 10.1086/421054 15106121
    • YZ Chen CL Bennett HM Huynh, et al. 2004 DNA/RNA helicase gene mutations in a form of juvenile amyotrophic lateral sclerosis (ALS4) Am J Hum Genet 74 1128 1135 10.1086/421054 15106121
    • (2004) Am J Hum Genet , vol.74 , pp. 1128-1135
    • Chen, Y.Z.1    Bennett, C.L.2    Huynh, H.M.3
  • 15
    • 77649310360 scopus 로고    scopus 로고
    • Association study between XRCC1 gene polymorphisms and sporadic amyotrophic lateral sclerosis
    • Coppede F, Migheli F, Lo Gerfo A et al (2010) Association study between XRCC1 gene polymorphisms and sporadic amyotrophic lateral sclerosis. Amyotroph Lateral Scler 11(1-2):122-124
    • (2010) Amyotroph Lateral Scler , vol.11 , Issue.1-2 , pp. 122-124
    • Coppede, F.1    Migheli, F.2    Lo Gerfo, A.3
  • 16
    • 34547098357 scopus 로고    scopus 로고
    • The role of the phosphoinositides at the Golgi complex
    • De Matteis MA, D'Angelo G (2007) The role of the phosphoinositides at the Golgi complex. Biochem Soc Symp (74):107-116
    • (2007) Biochem Soc Symp , vol.74 , pp. 107-116
    • De Matteis, M.A.1    D'Angelo, G.2
  • 17
    • 33645980992 scopus 로고    scopus 로고
    • Increased genomic instability is not a prerequisite for shortened lifespan in DNA repair deficient mice
    • 16472827
    • ME Dolle RA Busuttil AM Garcia, et al. 2006 Increased genomic instability is not a prerequisite for shortened lifespan in DNA repair deficient mice Mutat Res 596 22 35 16472827
    • (2006) Mutat Res , vol.596 , pp. 22-35
    • Dolle, M.E.1    Busuttil, R.A.2    Garcia, A.M.3
  • 18
    • 34548473612 scopus 로고    scopus 로고
    • Factors contributing to neuromuscular impairment and sarcopenia during aging
    • 10.1016/j.physbeh.2007.05.040 17585972
    • E Edstrom M Altun E Bergman, et al. 2007 Factors contributing to neuromuscular impairment and sarcopenia during aging Physiol Behav 92 129 135 10.1016/j.physbeh.2007.05.040 17585972
    • (2007) Physiol Behav , vol.92 , pp. 129-135
    • Edstrom, E.1    Altun, M.2    Bergman, E.3
  • 19
    • 4444339833 scopus 로고    scopus 로고
    • Oxidative DNA damage and disease: Induction, repair and significance
    • 10.1016/j.mrrev.2003.11.001 15341901
    • MD Evans M Dizdaroglu MS Cooke 2004 Oxidative DNA damage and disease: induction, repair and significance Mutat Res 567 1 61 10.1016/j.mrrev.2003.11. 001 15341901
    • (2004) Mutat Res , vol.567 , pp. 1-61
    • Evans, M.D.1    Dizdaroglu, M.2    Cooke, M.S.3
  • 20
    • 18644381734 scopus 로고    scopus 로고
    • ATF3 induction following DNA damage is regulated by distinct signaling pathways and over-expression of ATF3 protein suppresses cells growth
    • 10.1038/sj.onc.1205896 12386811
    • F Fan S Jin SA Amundson, et al. 2002 ATF3 induction following DNA damage is regulated by distinct signaling pathways and over-expression of ATF3 protein suppresses cells growth Oncogene 21 7488 7496 10.1038/sj.onc.1205896 12386811
    • (2002) Oncogene , vol.21 , pp. 7488-7496
    • Fan, F.1    Jin, S.2    Amundson, S.A.3
  • 22
    • 33845518305 scopus 로고    scopus 로고
    • DNA repair in neurons: So if they don't divide what's to repair?
    • 16879837
    • ML Fishel MR Vasko MR Kelley 2007 DNA repair in neurons: so if they don't divide what's to repair? Mutat Res 614 24 36 16879837
    • (2007) Mutat Res , vol.614 , pp. 24-36
    • Fishel, M.L.1    Vasko, M.R.2    Kelley, M.R.3
  • 23
    • 0026648674 scopus 로고
    • Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation
    • 10.1083/jcb.119.3.493 1400587
    • Y Gavrieli Y Sherman SA Ben-Sasson 1992 Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation J Cell Biol 119 493 501 10.1083/jcb.119.3.493 1400587
    • (1992) J Cell Biol , vol.119 , pp. 493-501
    • Gavrieli, Y.1    Sherman, Y.2    Ben-Sasson, S.A.3
  • 24
    • 33744531110 scopus 로고    scopus 로고
    • Fragmentation of the Golgi apparatus in neurodegenerative diseases and cell death
    • 10.1016/j.jns.2006.01.019 16545397
    • NK Gonatas A Stieber JO Gonatas 2006 Fragmentation of the Golgi apparatus in neurodegenerative diseases and cell death J Neurol Sci 246 21 30 10.1016/j.jns.2006.01.019 16545397
    • (2006) J Neurol Sci , vol.246 , pp. 21-30
    • Gonatas, N.K.1    Stieber, A.2    Gonatas, J.O.3
  • 25
    • 0035948624 scopus 로고    scopus 로고
    • The molecular biology and nomenclature of the activating transcription factor/cAMP responsive element binding family of transcription factors: Activating transcription factor proteins and homeostasis
    • 10.1016/S0378-1119(01)00551-0 11483355
    • T Hai MG Hartman 2001 The molecular biology and nomenclature of the activating transcription factor/cAMP responsive element binding family of transcription factors: activating transcription factor proteins and homeostasis Gene 273 1 11 10.1016/S0378-1119(01)00551-0 11483355
    • (2001) Gene , vol.273 , pp. 1-11
    • Hai, T.1    Hartman, M.G.2
  • 26
    • 70349859881 scopus 로고    scopus 로고
    • DNA damage, aging, and cancer
    • 10.1056/NEJMra0804615 19812404
    • JH Hoeijmakers 2009 DNA damage, aging, and cancer N Engl J Med 361 1475 1485 10.1056/NEJMra0804615 19812404
    • (2009) N Engl J Med , vol.361 , pp. 1475-1485
    • Hoeijmakers, J.H.1
  • 27
    • 0033532342 scopus 로고    scopus 로고
    • Action of DNA repair endonuclease ERCC1/XPF in living cells
    • 10.1126/science.284.5416.958 10320375
    • AB Houtsmuller S Rademakers AL Nigg, et al. 1999 Action of DNA repair endonuclease ERCC1/XPF in living cells Science 284 958 961 10.1126/science.284. 5416.958 10320375
    • (1999) Science , vol.284 , pp. 958-961
    • Houtsmuller, A.B.1    Rademakers, S.2    Nigg, A.L.3
  • 28
    • 39849103473 scopus 로고    scopus 로고
    • Neuron-specific expression of mutant superoxide dismutase is sufficient to induce amyotrophic lateral sclerosis in transgenic mice
    • 10.1523/JNEUROSCI.5258-07.2008 18305242
    • D Jaarsma E Teuling ED Haasdijk, et al. 2008 Neuron-specific expression of mutant superoxide dismutase is sufficient to induce amyotrophic lateral sclerosis in transgenic mice J Neurosci 28 2075 2088 10.1523/JNEUROSCI.5258-07. 2008 18305242
    • (2008) J Neurosci , vol.28 , pp. 2075-2088
    • Jaarsma, D.1    Teuling, E.2    Haasdijk, E.D.3
  • 29
    • 33847056347 scopus 로고    scopus 로고
    • First reported patient with human ERCC1 deficiency has cerebro-oculo-facio-skeletal syndrome with a mild defect in nucleotide excision repair and severe developmental failure
    • 10.1086/512486 17273966
    • NG Jaspers A Raams MC Silengo, et al. 2007 First reported patient with human ERCC1 deficiency has cerebro-oculo-facio-skeletal syndrome with a mild defect in nucleotide excision repair and severe developmental failure Am J Hum Genet 80 457 466 10.1086/512486 17273966
    • (2007) Am J Hum Genet , vol.80 , pp. 457-466
    • Jaspers, N.G.1    Raams, A.2    Silengo, M.C.3
  • 30
    • 34247169028 scopus 로고    scopus 로고
    • Xeroderma pigmentosum, trichothiodystrophy and Cockayne syndrome: A complex genotype-phenotype relationship
    • 10.1016/j.neuroscience.2006.12.020 17276014
    • KH Kraemer NJ Patronas R Schiffmann, et al. 2007 Xeroderma pigmentosum, trichothiodystrophy and Cockayne syndrome: a complex genotype-phenotype relationship Neuroscience 145 1388 1396 10.1016/j.neuroscience.2006.12.020 17276014
    • (2007) Neuroscience , vol.145 , pp. 1388-1396
    • Kraemer, K.H.1    Patronas, N.J.2    Schiffmann, R.3
  • 31
    • 62149141328 scopus 로고    scopus 로고
    • Rethinking ALS: The FUS about TDP-43
    • 10.1016/j.cell.2009.03.006 19303844
    • C Lagier-Tourenne DW Cleveland 2009 Rethinking ALS: the FUS about TDP-43 Cell 136 1001 1004 10.1016/j.cell.2009.03.006 19303844
    • (2009) Cell , vol.136 , pp. 1001-1004
    • Lagier-Tourenne, C.1    Cleveland, D.W.2
  • 32
    • 0028921023 scopus 로고
    • Effects of ageing on the motor unit
    • 10.1016/0301-0082(95)98601-Z 7617890
    • L Larsson T Ansved 1995 Effects of ageing on the motor unit Prog Neurobiol 45 397 458 10.1016/0301-0082(95)98601-Z 7617890
    • (1995) Prog Neurobiol , vol.45 , pp. 397-458
    • Larsson, L.1    Ansved, T.2
  • 33
    • 37549033922 scopus 로고    scopus 로고
    • A neurological phenotype in mice with DNA repair gene Ercc1 deficiency
    • 10.1016/j.dnarep.2007.10.005 18221731
    • NJ Lawrence JJ Sacco DG Brownstein, et al. 2008 A neurological phenotype in mice with DNA repair gene Ercc1 deficiency DNA Repair 7 281 291 10.1016/j.dnarep.2007.10.005 18221731
    • (2008) DNA Repair , vol.7 , pp. 281-291
    • Lawrence, N.J.1    Sacco, J.J.2    Brownstein, D.G.3
  • 34
    • 33646807832 scopus 로고    scopus 로고
    • The P53 pathway: What questions remain to be explored?
    • 10.1038/sj.cdd.4401910 16557269
    • AJ Levine W Hu Z Feng 2006 The P53 pathway: what questions remain to be explored? Cell Death Differ 13 1027 1036 10.1038/sj.cdd.4401910 16557269
    • (2006) Cell Death Differ , vol.13 , pp. 1027-1036
    • Levine, A.J.1    Hu, W.2    Feng, Z.3
  • 35
    • 4544259868 scopus 로고    scopus 로고
    • Transcription-guarding the genome by sensing DNA damage
    • 10.1038/nrc1435 15343279
    • M Ljungman DP Lane 2004 Transcription-guarding the genome by sensing DNA damage Nat Rev Cancer 4 727 737 10.1038/nrc1435 15343279
    • (2004) Nat Rev Cancer , vol.4 , pp. 727-737
    • Ljungman, M.1    Lane, D.P.2
  • 36
    • 43249118458 scopus 로고    scopus 로고
    • DNA damage and repair: Relevance to mechanisms of neurodegeneration
    • 10.1097/NEN.0b013e31816ff780 18431258
    • LJ Martin 2008 DNA damage and repair: relevance to mechanisms of neurodegeneration J Neuropathol Exp Neurol 67 377 387 10.1097/NEN. 0b013e31816ff780 18431258
    • (2008) J Neuropathol Exp Neurol , vol.67 , pp. 377-387
    • Martin, L.J.1
  • 37
    • 58549092574 scopus 로고    scopus 로고
    • DNA repair deficiency and neurological disease
    • 10.1038/nrn2559 19145234
    • PJ McKinnon 2009 DNA repair deficiency and neurological disease Nat Rev Neurosci 10 100 112 10.1038/nrn2559 19145234
    • (2009) Nat Rev Neurosci , vol.10 , pp. 100-112
    • McKinnon, P.J.1
  • 38
    • 0027378895 scopus 로고
    • Mice with DNA repair gene (ERCC-1) deficiency have elevated levels of p53, liver nuclear abnormalities and die before weaning
    • 10.1038/ng1193-217 8275084
    • J McWhir J Selfridge DJ Harrison, et al. 1993 Mice with DNA repair gene (ERCC-1) deficiency have elevated levels of p53, liver nuclear abnormalities and die before weaning Nat Genet 5 217 224 10.1038/ng1193-217 8275084
    • (1993) Nat Genet , vol.5 , pp. 217-224
    • McWhir, J.1    Selfridge, J.2    Harrison, D.J.3
  • 39
    • 40449112147 scopus 로고    scopus 로고
    • Mouse models for xeroderma pigmentosum group A and group C show divergent cancer phenotypes
    • 10.1158/0008-5472.CAN-07-6067 18316597
    • JP Melis SW Wijnhoven RB Beems, et al. 2008 Mouse models for xeroderma pigmentosum group A and group C show divergent cancer phenotypes Cancer Res 68 1347 1353 10.1158/0008-5472.CAN-07-6067 18316597
    • (2008) Cancer Res , vol.68 , pp. 1347-1353
    • Melis, J.P.1    Wijnhoven, S.W.2    Beems, R.B.3
  • 40
    • 41149113045 scopus 로고    scopus 로고
    • Selective vulnerability of motor neurons and dissociation of pre- and post-synaptic pathology at the neuromuscular junction in mouse models of spinal muscular atrophy
    • 10.1093/hmg/ddm367 18065780
    • LM Murray LH Comley D Thomson, et al. 2008 Selective vulnerability of motor neurons and dissociation of pre- and post-synaptic pathology at the neuromuscular junction in mouse models of spinal muscular atrophy Hum Mol Genet 17 949 962 10.1093/hmg/ddm367 18065780
    • (2008) Hum Mol Genet , vol.17 , pp. 949-962
    • Murray, L.M.1    Comley, L.H.2    Thomson, D.3
  • 41
    • 77949889554 scopus 로고    scopus 로고
    • Pre-symptomatic development of lower motor neuron connectivity in a mouse model of severe spinal muscular atrophy
    • 10.1093/hmg/ddp506 19884170
    • LM Murray S Lee D Baumer, et al. 2010 Pre-symptomatic development of lower motor neuron connectivity in a mouse model of severe spinal muscular atrophy Hum Mol Genet 19 420 433 10.1093/hmg/ddp506 19884170
    • (2010) Hum Mol Genet , vol.19 , pp. 420-433
    • Murray, L.M.1    Lee, S.2    Baumer, D.3
  • 42
    • 77949909934 scopus 로고    scopus 로고
    • Neuromuscular synaptic vulnerability in motor neurone disease: Amyotrophic lateral sclerosis and spinal muscular atrophy
    • 20202121
    • LM Murray K Talbot TH Gillingwater 2010 Neuromuscular synaptic vulnerability in motor neurone disease: amyotrophic lateral sclerosis and spinal muscular atrophy Neuropathol Appl Neurobiol 36 133 156 20202121
    • (2010) Neuropathol Appl Neurobiol , vol.36 , pp. 133-156
    • Murray, L.M.1    Talbot, K.2    Gillingwater, T.H.3
  • 43
    • 0020973516 scopus 로고
    • Use of excitatory amino acids to make axon sparing lesions of the hypothalamus
    • 10.1016/S0076-6879(83)03027-X 6199648
    • JV Nadler DA Evenson 1983 Use of excitatory amino acids to make axon sparing lesions of the hypothalamus Meth Enzymol 103 393 400 10.1016/S0076-6879(83)03027-X 6199648
    • (1983) Meth Enzymol , vol.103 , pp. 393-400
    • Nadler, J.V.1    Evenson, D.A.2
  • 44
    • 0029595302 scopus 로고
    • Characterization of a cis-Golgi matrix protein, GM130
    • 10.1083/jcb.131.6.1715 8557739
    • N Nakamura C Rabouille R Watson, et al. 1995 Characterization of a cis-Golgi matrix protein, GM130 J Cell Biol 131 1715 1726 10.1083/jcb.131.6.1715 8557739
    • (1995) J Cell Biol , vol.131 , pp. 1715-1726
    • Nakamura, N.1    Rabouille, C.2    Watson, R.3
  • 45
    • 55149113452 scopus 로고    scopus 로고
    • Impaired spermatogenesis and elevated spontaneous tumorigenesis in xeroderma pigmentosum group A gene (Xpa)-deficient mice
    • 10.1016/j.dnarep.2008.08.003 18790090
    • H Nakane S Hirota PJ Brooks, et al. 2008 Impaired spermatogenesis and elevated spontaneous tumorigenesis in xeroderma pigmentosum group A gene (Xpa)-deficient mice DNA Repair 7 1938 1950 10.1016/j.dnarep.2008.08.003 18790090
    • (2008) DNA Repair , vol.7 , pp. 1938-1950
    • Nakane, H.1    Hirota, S.2    Brooks, P.J.3
  • 46
    • 33749632259 scopus 로고    scopus 로고
    • Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
    • 10.1126/science.1134108 17023659
    • M Neumann DM Sampathu LK Kwong, et al. 2006 Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis Science 314 130 133 10.1126/science.1134108 17023659
    • (2006) Science , vol.314 , pp. 130-133
    • Neumann, M.1    Sampathu, D.M.2    Kwong, L.K.3
  • 47
    • 59649086176 scopus 로고    scopus 로고
    • Molecular neuropathology of TDP-43 proteinopathies
    • 10.3390/ijms10010232 19333444
    • M Neumann 2009 Molecular neuropathology of TDP-43 proteinopathies Int J Mol Sci 10 232 246 10.3390/ijms10010232 19333444
    • (2009) Int J Mol Sci , vol.10 , pp. 232-246
    • Neumann, M.1
  • 48
    • 65249161758 scopus 로고    scopus 로고
    • Oxysterol binding protein-related Protein 9 (ORP9) is a cholesterol transfer protein that regulates Golgi structure and function
    • 10.1091/mbc.E08-09-0905 19129476
    • M Ngo ND Ridgway 2009 Oxysterol binding protein-related Protein 9 (ORP9) is a cholesterol transfer protein that regulates Golgi structure and function Mol Biol Cell 20 1388 1399 10.1091/mbc.E08-09-0905 19129476
    • (2009) Mol Biol Cell , vol.20 , pp. 1388-1399
    • Ngo, M.1    Ridgway, N.D.2
  • 49
    • 33845914051 scopus 로고    scopus 로고
    • A new progeroid syndrome reveals that genotoxic stress suppresses the somatotroph axis
    • 10.1038/nature05456 17183314
    • LJ Niedernhofer GA Garinis A Raams, et al. 2006 A new progeroid syndrome reveals that genotoxic stress suppresses the somatotroph axis Nature 444 1038 1043 10.1038/nature05456 17183314
    • (2006) Nature , vol.444 , pp. 1038-1043
    • Niedernhofer, L.J.1    Garinis, G.A.2    Raams, A.3
  • 50
    • 49949152164 scopus 로고    scopus 로고
    • Nucleotide excision repair deficient mouse models and neurological disease
    • 10.1016/j.dnarep.2007.12.006 18272436
    • LJ Niedernhofer 2008 Nucleotide excision repair deficient mouse models and neurological disease DNA Repair 7 1180 1189 10.1016/j.dnarep.2007.12.006 18272436
    • (2008) DNA Repair , vol.7 , pp. 1180-1189
    • Niedernhofer, L.J.1
  • 51
    • 34247178359 scopus 로고    scopus 로고
    • DNA repair in differentiated cells: Some new answers to old questions
    • 10.1016/j.neuroscience.2006.07.006 16920273
    • T Nouspikel 2007 DNA repair in differentiated cells: some new answers to old questions Neuroscience 145 1213 1221 10.1016/j.neuroscience.2006.07.006 16920273
    • (2007) Neuroscience , vol.145 , pp. 1213-1221
    • Nouspikel, T.1
  • 52
    • 34548614799 scopus 로고    scopus 로고
    • Defective DNA repair and neurodegenerative disease
    • 10.1016/j.cell.2007.08.043 17889645
    • U Rass I Ahel SC West 2007 Defective DNA repair and neurodegenerative disease Cell 130 991 1004 10.1016/j.cell.2007.08.043 17889645
    • (2007) Cell , vol.130 , pp. 991-1004
    • Rass, U.1    Ahel, I.2    West, S.C.3
  • 53
    • 58149343875 scopus 로고    scopus 로고
    • Galectin-3/MAC-2, Ras and PI3K activate complement receptor-3 and scavenger receptor-AI/II mediated myelin phagocytosis in microglia
    • 10.1002/glia.20713 18615637
    • S Rotshenker F Reichert M Gitik, et al. 2008 Galectin-3/MAC-2, Ras and PI3K activate complement receptor-3 and scavenger receptor-AI/II mediated myelin phagocytosis in microglia Glia 56 1607 1613 10.1002/glia.20713 18615637
    • (2008) Glia , vol.56 , pp. 1607-1613
    • Rotshenker, S.1    Reichert, F.2    Gitik, M.3
  • 54
    • 33644661156 scopus 로고    scopus 로고
    • RNA polymerase encounters with DNA damage: Transcription-coupled repair or transcriptional mutagenesis?
    • 10.1021/cr040466q 16464015
    • TT Saxowsky PW Doetsch 2006 RNA polymerase encounters with DNA damage: transcription-coupled repair or transcriptional mutagenesis? Chem Rev 106 474 488 10.1021/cr040466q 16464015
    • (2006) Chem Rev , vol.106 , pp. 474-488
    • Saxowsky, T.T.1    Doetsch, P.W.2
  • 55
    • 0035890838 scopus 로고    scopus 로고
    • Correction of liver dysfunction in DNA repair-deficient mice with an ERCC1 transgene
    • 10.1093/nar/29.22.4541 11713303
    • J Selfridge KT Hsia NJ Redhead DW Melton 2001 Correction of liver dysfunction in DNA repair-deficient mice with an ERCC1 transgene Nucleic Acids Res 29 4541 4550 10.1093/nar/29.22.4541 11713303
    • (2001) Nucleic Acids Res , vol.29 , pp. 4541-4550
    • Selfridge, J.1    Hsia, K.T.2    Redhead, N.J.3    Melton, D.W.4
  • 56
    • 34250775522 scopus 로고    scopus 로고
    • Senataxin, defective in ataxia oculomotor apraxia type 2, is involved in the defense against oxidative DNA damage
    • 10.1083/jcb.200701042 17562789
    • A Suraweera OJ Becherel P Chen, et al. 2007 Senataxin, defective in ataxia oculomotor apraxia type 2, is involved in the defense against oxidative DNA damage J Cell Biol 177 969 979 10.1083/jcb.200701042 17562789
    • (2007) J Cell Biol , vol.177 , pp. 969-979
    • Suraweera, A.1    Becherel, O.J.2    Chen, P.3
  • 57
    • 34848904785 scopus 로고    scopus 로고
    • Motor neuron disease-associated mutant vesicle-associated membrane protein-associated protein (VAP) B recruits wild-type VAPs into endoplasmic reticulum-derived tubular aggregates
    • 10.1523/JNEUROSCI.2661-07.2007 17804640
    • E Teuling S Ahmed E Haasdijk, et al. 2007 Motor neuron disease-associated mutant vesicle-associated membrane protein-associated protein (VAP) B recruits wild-type VAPs into endoplasmic reticulum-derived tubular aggregates J Neurosci 27 9801 9815 10.1523/JNEUROSCI.2661-07.2007 17804640
    • (2007) J Neurosci , vol.27 , pp. 9801-9815
    • Teuling, E.1    Ahmed, S.2    Haasdijk, E.3
  • 58
    • 50849110466 scopus 로고    scopus 로고
    • A novel mouse model with impaired dynein/dynactin function develops amyotrophic lateral sclerosis (ALS)-like features in motor neurons and improves lifespan in SOD1-ALS mice
    • 10.1093/hmg/ddn182 18579581
    • E Teuling V van Dis PS Wulf, et al. 2008 A novel mouse model with impaired dynein/dynactin function develops amyotrophic lateral sclerosis (ALS)-like features in motor neurons and improves lifespan in SOD1-ALS mice Hum Mol Genet 17 2849 2862 10.1093/hmg/ddn182 18579581
    • (2008) Hum Mol Genet , vol.17 , pp. 2849-2862
    • Teuling, E.1    Van Dis, V.2    Wulf, P.S.3
  • 59
    • 1542309071 scopus 로고    scopus 로고
    • Growth retardation, early death, and DNA repair defects in mice deficient for the nucleotide excision repair enzyme XPF
    • 10.1128/MCB.24.3.1200-1205.2004 14729965
    • M Tian R Shinkura N Shinkura FW Alt 2004 Growth retardation, early death, and DNA repair defects in mice deficient for the nucleotide excision repair enzyme XPF Mol Cell Biol 24 1200 1205 10.1128/MCB.24.3.1200-1205.2004 14729965
    • (2004) Mol Cell Biol , vol.24 , pp. 1200-1205
    • Tian, M.1    Shinkura, R.2    Shinkura, N.3    Alt, F.W.4
  • 60
    • 66849138115 scopus 로고    scopus 로고
    • ATF3 and p15PAF are novel gatekeepers of genomic integrity upon UV stress
    • 10.1038/cdd.2009.2 19219066
    • L Turchi M Fareh E Aberdam, et al. 2009 ATF3 and p15PAF are novel gatekeepers of genomic integrity upon UV stress Cell Death Differ 16 728 737 10.1038/cdd.2009.2 19219066
    • (2009) Cell Death Differ , vol.16 , pp. 728-737
    • Turchi, L.1    Fareh, M.2    Aberdam, E.3
  • 61
    • 64649086140 scopus 로고    scopus 로고
    • Recent advances in the genetics of amyotrophic lateral sclerosis
    • 10.1007/s11910-009-0030-9 19348708
    • PN Valdmanis H Daoud PA Dion GA Rouleau 2009 Recent advances in the genetics of amyotrophic lateral sclerosis Curr Neurol Neurosci Rep 9 198 205 10.1007/s11910-009-0030-9 19348708
    • (2009) Curr Neurol Neurosci Rep , vol.9 , pp. 198-205
    • Valdmanis, P.N.1    Daoud, H.2    Dion, P.A.3    Rouleau, G.A.4
  • 62
    • 33846030099 scopus 로고    scopus 로고
    • Impaired genome maintenance suppresses the growth hormone-insulin-like growth factor 1 axis in mice with Cockayne syndrome
    • 10.1371/journal.pbio.0050002 17326724
    • I van der Pluijm GA Garinis RM Brandt, et al. 2007 Impaired genome maintenance suppresses the growth hormone-insulin-like growth factor 1 axis in mice with Cockayne syndrome PLoS Biol 5 e2 10.1371/journal.pbio.0050002 17326724
    • (2007) PLoS Biol , vol.5 , pp. 2
    • Van Der Pluijm, I.1    Garinis, G.A.2    Brandt, R.M.3
  • 63
    • 33847210262 scopus 로고    scopus 로고
    • Rescue of neurological deficits in a mouse model for Angelman syndrome by reduction of alphaCaMKII inhibitory phosphorylation
    • 10.1038/nn1845 17259980
    • GM van Woerden KD Harris MR Hojjati, et al. 2007 Rescue of neurological deficits in a mouse model for Angelman syndrome by reduction of alphaCaMKII inhibitory phosphorylation Nat Neurosci 10 280 282 10.1038/nn1845 17259980
    • (2007) Nat Neurosci , vol.10 , pp. 280-282
    • Van Woerden, G.M.1    Harris, K.D.2    Hojjati, M.R.3
  • 64
    • 27644485845 scopus 로고    scopus 로고
    • ATF3 expression precedes death of spinal motoneurons in amyotrophic lateral sclerosis-SOD1 transgenic mice and correlates with c-Jun phosphorylation, CHOP expression, somato-dendritic ubiquitination and Golgi fragmentation
    • 10.1111/j.1460-9568.2005.04389.x 16262628
    • AS Vlug E Teuling ED Haasdijk, et al. 2005 ATF3 expression precedes death of spinal motoneurons in amyotrophic lateral sclerosis-SOD1 transgenic mice and correlates with c-Jun phosphorylation, CHOP expression, somato-dendritic ubiquitination and Golgi fragmentation Eur J Neurosci 22 1881 1894 10.1111/j.1460-9568.2005.04389.x 16262628
    • (2005) Eur J Neurosci , vol.22 , pp. 1881-1894
    • Vlug, A.S.1    Teuling, E.2    Haasdijk, E.D.3
  • 65
    • 12644266319 scopus 로고    scopus 로고
    • Disruption of mouse ERCC1 results in a novel repair syndrome with growth failure, nuclear abnormalities and senescence
    • 10.1016/S0960-9822(06)00190-4 9197240
    • G Weeda I Donker J de Wit, et al. 1997 Disruption of mouse ERCC1 results in a novel repair syndrome with growth failure, nuclear abnormalities and senescence Curr Biol 7 427 439 10.1016/S0960-9822(06)00190-4 9197240
    • (1997) Curr Biol , vol.7 , pp. 427-439
    • Weeda, G.1    Donker, I.2    De Wit, J.3
  • 66
    • 33847007529 scopus 로고    scopus 로고
    • The mechanics of base excision repair, and its relationship to aging and disease
    • 10.1016/j.dnarep.2006.10.017 17112792
    • DM Wilson 3rd VA Bohr 2007 The mechanics of base excision repair, and its relationship to aging and disease DNA Repair 6 544 559 10.1016/j.dnarep.2006. 10.017 17112792
    • (2007) DNA Repair , vol.6 , pp. 544-559
    • Wilson III, D.M.1    Bohr, V.A.2
  • 67
    • 33751243629 scopus 로고    scopus 로고
    • Neuronal intermediate filaments and ALS: A new look at an old question
    • 17045786
    • S Xiao J McLean J Robertson 2006 Neuronal intermediate filaments and ALS: a new look at an old question Biochim Biophys Acta 1762 1001 1012 17045786
    • (2006) Biochim Biophys Acta , vol.1762 , pp. 1001-1012
    • Xiao, S.1    McLean, J.2    Robertson, J.3
  • 68
    • 22744442218 scopus 로고    scopus 로고
    • Activating transcription factor 3, a stress sensor, activates p53 by blocking its ubiquitination
    • 10.1038/sj.emboj.7600712 15933712
    • C Yan D Lu T Hai DD Boyd 2005 Activating transcription factor 3, a stress sensor, activates p53 by blocking its ubiquitination EMBO J 24 2425 2435 10.1038/sj.emboj.7600712 15933712
    • (2005) EMBO J , vol.24 , pp. 2425-2435
    • Yan, C.1    Lu, D.2    Hai, T.3    Boyd, D.D.4
  • 69
    • 0030817291 scopus 로고    scopus 로고
    • Neurofilaments and orthograde transport are reduced in ventral root axons of transgenic mice that express human SOD1 with a G93A mutation
    • 10.1083/jcb.139.5.1307 9382875
    • B Zhang P Tu F Abtahian, et al. 1997 Neurofilaments and orthograde transport are reduced in ventral root axons of transgenic mice that express human SOD1 with a G93A mutation J Cell Biol 139 1307 1315 10.1083/jcb.139.5.1307 9382875
    • (1997) J Cell Biol , vol.139 , pp. 1307-1315
    • Zhang, B.1    Tu, P.2    Abtahian, F.3
  • 70
    • 0347416975 scopus 로고    scopus 로고
    • ERCC1/XPF removes the 3′ overhang from uncapped telomeres and represses formation of telomeric DNA-containing double minute chromosomes
    • 10.1016/S1097-2765(03)00478-7 14690602
    • XD Zhu L Niedernhofer B Kuster, et al. 2003 ERCC1/XPF removes the 3′ overhang from uncapped telomeres and represses formation of telomeric DNA-containing double minute chromosomes Mol Cell 12 1489 1498 10.1016/S1097-2765(03)00478-7 14690602
    • (2003) Mol Cell , vol.12 , pp. 1489-1498
    • Zhu, X.D.1    Niedernhofer, L.2    Kuster, B.3


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